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Conserved domains on  [gi|12644413|sp|Q14202|]
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RecName: Full=Zinc finger MYM-type protein 3; AltName: Full=Zinc finger protein 261

Protein Classification

DHHC family palmitoyltransferase; LCP family protein( domain architecture ID 13363461)

DHHC family palmitoyltransferase may catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes| LytR-CpsA-Psr (LCP) family protein is implicated in the attachment of anionic polymers to cell wall peptidoglycan in bacteria

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1185-1353 1.06e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


:

Pssm-ID: 463430  Cd Length: 162  Bit Score: 270.29  E-value: 1.06e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   1185 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1264
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   1265 kGRDTGPGKRKREDEA--PILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1342
Cdd:pfam12012   73 -PDQVETGGRKKRDEGvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 12644413   1343 MLESMLNRILA 1353
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 2-305 1.95e-12

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 72.51  E-value: 1.95e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413     2 DPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPAGL-EKDPGVLDGA 76
Cdd:PHA03307   66 EPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLsEMLRPVGSPG 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    77 TELLGLGGLLYKAPSPPEVD--HGPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGllEPLAP----DSPI 150
Cdd:PHA03307  146 PPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISAsassPAPA 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   151 TLQSPHIEEEETTSIATARRGSP---GQEEELPQGQPQSPNAP-----PSPSVGETLGDGINSSQTKPGGSSPPAHPSLP 222
Cdd:PHA03307  224 PGRSAADDAGASSSDSSSSESSGcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPSPSPSSP 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   223 GDGLTAKASEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLR-SSVSQRAG 301
Cdd:PHA03307  304 GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRApSSPAASAG 383


                  ....
gi 12644413   302 RSAV 305
Cdd:PHA03307  384 RPTR 387
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 493-532 4.27e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.75  E-value: 4.27e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    493 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 532
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 446-488 7.34e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 7.34e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 12644413    446 LKTNCCDQCGAYIYTKtgsPGPELLFHEGQQKRFCNTTCLGAY 488
Cdd:pfam06467    1 LVKATCWFCKKLIKNK---PTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 348-389 8.43e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 8.43e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 12644413    348 SGKKTCTFCKKEIWNTKDsvVAQTGSGGSFHEFCTSVCLSLY 389
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPT--VIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 586-623 1.24e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.24e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    586 GIHLSCHYCHSLFSGKPE--VLDWQDQVFQFCCRDCCEDF 623
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 674-710 3.05e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 3.05e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    674 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKSKY 710
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 715-751 1.79e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.79e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    715 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 751
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 541-578 8.21e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.12  E-value: 8.21e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    541 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 578
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 628-664 1.82e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.82e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    628 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 664
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
311-347 3.14e-03

metallochaperone-like domain;


:

Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.59  E-value: 3.14e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 12644413     311 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTFSKKP 347
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 404-440 4.47e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.47e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    404 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 440
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1185-1353 1.06e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 270.29  E-value: 1.06e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   1185 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1264
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   1265 kGRDTGPGKRKREDEA--PILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1342
Cdd:pfam12012   73 -PDQVETGGRKKRDEGvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 12644413   1343 MLESMLNRILA 1353
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-305 1.95e-12

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 72.51  E-value: 1.95e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413     2 DPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPAGL-EKDPGVLDGA 76
Cdd:PHA03307   66 EPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLsEMLRPVGSPG 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    77 TELLGLGGLLYKAPSPPEVD--HGPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGllEPLAP----DSPI 150
Cdd:PHA03307  146 PPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISAsassPAPA 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   151 TLQSPHIEEEETTSIATARRGSP---GQEEELPQGQPQSPNAP-----PSPSVGETLGDGINSSQTKPGGSSPPAHPSLP 222
Cdd:PHA03307  224 PGRSAADDAGASSSDSSSSESSGcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPSPSPSSP 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   223 GDGLTAKASEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLR-SSVSQRAG 301
Cdd:PHA03307  304 GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRApSSPAASAG 383


                  ....
gi 12644413   302 RSAV 305
Cdd:PHA03307  384 RPTR 387
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 493-532 4.27e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.75  E-value: 4.27e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    493 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 532
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 12-251 1.02e-06

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 53.14  E-value: 1.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   12 PLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPAGLEKDPGVLD-GATELLGLGGLLYKAP 90
Cdd:COG5180  158 SDPILAKDPDGDSASTLPPPAEKLDKVLTEPRDALKDSPEKLDRPKVEVKDEAQEEPPDLTGGaDHPRPEAASSPKVDPP 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   91 SPPE-------VDHGPEGTLAWDAGDqtLEPGPGGQTPEvvPPDPGAGANSCSPEGlleplAPDSPITLQSPHIEEEETT 163
Cdd:COG5180  238 STSEarsrpatVDAQPEMRPPADAKE--RRRAAIGDTPA--AEPPGLPVLEAGSEP-----QSDAPEAETARPIDVKGVA 308

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413  164 SIATA-------------RRGSPGQEEELPQGQPQS---PNAPPSPSVgetlgdgiNSSQTKPGGSSPPAHPSlPGDGLT 227
Cdd:COG5180  309 SAPPAtrpvrppggardpGTPRPGQPTERPAGVPEAasdAGQPPSAYP--------PAEEAVPGKPLEQGAPR-PGSSGG 379

                        250       260
                 ....*....|....*....|....
gi 12644413  228 AKASEKPPERKRSERVRRAEPPKP 251
Cdd:COG5180  380 DGAPFQPPNGAPQPGLGRRGAPGP 403
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 34-270 6.39e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 50.69  E-value: 6.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413     34 LLESQTAPTRGWAPPGPSPSSGALDLLD-TPAGlekdpgVLDGATELlglggllykAPSPPEVDHGPEGT----LAWDAG 108
Cdd:pfam05109  448 LPSSTHVPTNLTAPASTGPTVSTADVTSpTPAG------TTSGASPV---------TPSPSPRDNGTESKapdmTSPTSA 512

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    109 DQTLEPGPGGQTPEVVPPDPgagaNSCSPEglLEPLAPDSPITLQSPHIEEEE---TTSIATARRGSPGQEEELPQGQPQ 185
Cdd:pfam05109  513 VTTPTPNATSPTPAVTTPTP----NATSPT--LGKTSPTSAVTTPTPNATSPTpavTTPTPNATIPTLGKTSPTSAVTTP 586

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    186 SPNAPpSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEkppERKRSERVRRAEPPKPEVVDSTESIPVSDE 265
Cdd:pfam05109  587 TPNAT-SPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTG---QHNITSSSTSSMSLRPSSISETLSPSTSDN 662


                   ....*
gi 12644413    266 DSDAM 270
Cdd:pfam05109  663 STSHM 667
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 446-488 7.34e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 7.34e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 12644413    446 LKTNCCDQCGAYIYTKtgsPGPELLFHEGQQKRFCNTTCLGAY 488
Cdd:pfam06467    1 LVKATCWFCKKLIKNK---PTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 348-389 8.43e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 8.43e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 12644413    348 SGKKTCTFCKKEIWNTKDsvVAQTGSGGSFHEFCTSVCLSLY 389
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPT--VIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 586-623 1.24e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.24e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    586 GIHLSCHYCHSLFSGKPE--VLDWQDQVFQFCCRDCCEDF 623
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 674-710 3.05e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 3.05e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    674 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKSKY 710
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
498-536 5.79e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.59  E-value: 5.79e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 12644413     498 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 536
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 102-289 1.04e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 46.30  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   102 TLAWDAGDQ------TLEPGPGGQTpeVVPPDPGAGAnscspegLLEPlAPDSPItlqsPHIeeeetTSIATARRGSPGQ 175
Cdd:NF040712  152 QLSWTAGGSentahwTFDPGAHGGT--VTALDDEARW-------LIDP-DFGRPL----RPL-----ATVPRLAREPADA 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   176 EEELPQGQPQSPNAPPSPSV---GETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKRSERVRRAEPPKPE 252
Cdd:NF040712  213 RPEEVEPAPAAEGAPATDSDpaeAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAA 292

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 12644413   253 vvDSTESIPVSDEDSDAM-VDDPNDEDFVPFRPRRSPR 289
Cdd:NF040712  293 --EPPAPAPAAPAAPAAPeAEEPARPEPPPAPKPKRRR 328
TRASH smart00746
metallochaperone-like domain;
451-492 1.11e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 40.82  E-value: 1.11e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 12644413     451 CDQCGAYIYTKTGspgPELLFHEGQQKRFCNTTCLGAYKKKN 492
Cdd:smart00746    1 CSFCGKDIYNPGT---GIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 715-751 1.79e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.79e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    715 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 751
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 106-254 1.80e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 45.53  E-value: 1.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   106 DAGDQTLEPGPGGQTPEVVP-PDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEEEETTSIATARR-----GSPGQEEEL 179
Cdd:NF040712  182 DEARWLIDPDFGRPLRPLATvPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRrragvEQPEDEPVG 261

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 12644413   180 PQGQPQSPNAPPSPSVGETLGDGINSS--QTKPGGSSP--PAHPSLPGDGLTAKASEKPPERKRSERVRRAEPPKPEVV 254
Cdd:NF040712  262 PGAAPAAEPDEATRDAGEPPAPGAAETpeAAEPPAPAPaaPAAPAAPEAEEPARPEPPPAPKPKRRRRRASVPSWDDVL 340
TRASH smart00746
metallochaperone-like domain;
591-627 3.36e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.28  E-value: 3.36e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 12644413     591 CHYCHSLFS--GKPEVLDWQDQVFQFCCRDCCEDFKRLR 627
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
679-711 6.01e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.51  E-value: 6.01e-04
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 12644413     679 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKSKYL 711
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 541-578 8.21e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.12  E-value: 8.21e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    541 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 578
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 628-664 1.82e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.82e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    628 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 664
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
311-347 3.14e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.59  E-value: 3.14e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 12644413     311 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTFSKKP 347
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 404-440 4.47e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.47e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    404 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 440
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
546-580 6.64e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 6.64e-03
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 12644413     546 CSFCRRSLSDPCYYNKV--DRTVYQFCSPSCWTKFQR 580
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFKK 37
TRASH smart00746
metallochaperone-like domain;
720-755 9.02e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 9.02e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 12644413     720 CHACKRQGKLLETIH---WRGQIRHFCNQQCLLRFYSQQ 755
Cdd:smart00746    1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1185-1353 1.06e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 270.29  E-value: 1.06e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   1185 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1264
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   1265 kGRDTGPGKRKREDEA--PILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1342
Cdd:pfam12012   73 -PDQVETGGRKKRDEGvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 12644413   1343 MLESMLNRILA 1353
Cdd:pfam12012  152 TLESMLTRILL 162
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 2-305 1.95e-12

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 72.51  E-value: 1.95e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413     2 DPSDFPSPFDPLTLPEKPLAGD----LPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPAGL-EKDPGVLDGA 76
Cdd:PHA03307   66 EPPTGPPPGPGTEAPANESRSTptwsLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLsEMLRPVGSPG 145

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    77 TELLGLGGLLYKAPSPPEVD--HGPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGllEPLAP----DSPI 150
Cdd:PHA03307  146 PPPAASPPAAGASPAAVASDaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRS--SPISAsassPAPA 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   151 TLQSPHIEEEETTSIATARRGSP---GQEEELPQGQPQSPNAP-----PSPSVGETLGDGINSSQTKPGGSSPPAHPSLP 222
Cdd:PHA03307  224 PGRSAADDAGASSSDSSSSESSGcgwGPENECPLPRPAPITLPtriweASGWNGPSSRPGPASSSSSPRERSPSPSPSSP 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   223 GDGLTAKASEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLR-SSVSQRAG 301
Cdd:PHA03307  304 GSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRApSSPAASAG 383


                  ....
gi 12644413   302 RSAV 305
Cdd:PHA03307  384 RPTR 387
PHA03247 PHA03247
large tegument protein UL36; Provisional
 39-261 1.14e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.87  E-value: 1.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    39 TAPTRGWAPPGPSPSSGALDLLDTPAGLEKDPgvldgatellglggllykAPSPPEVDHGPEGTLAWDAGDQTLEPGPGG 118
Cdd:PHA03247 2677 SSPPQRPRRRAARPTVGSLTSLADPPPPPPTP------------------EPAPHALVSATPLPPGPAAARQASPALPAA 2738

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   119 QTPE------VVPPDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEELPQGQPQSPNAPPS 192
Cdd:PHA03247 2739 PAPPavpagpATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL 2818

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   193 PSVGETLGDGINSSQTKPGGSSPPAHP---SLPGDGLTAKA---SEKPPER--------KRSERVRRAepPKPEVVDSTE 258
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPpppSLPLGGSVAPGgdvRRRPPSRspaakpaaPARPPVRRL--ARPAVSRSTE 2896


                  ...
gi 12644413   259 SIP 261
Cdd:PHA03247 2897 SFA 2899
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 493-532 4.27e-07

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 47.75  E-value: 4.27e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    493 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 532
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
PBP1 COG5180
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ...
 12-251 1.02e-06

PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];


Pssm-ID: 444064 [Multi-domain]  Cd Length: 548  Bit Score: 53.14  E-value: 1.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   12 PLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPAGLEKDPGVLD-GATELLGLGGLLYKAP 90
Cdd:COG5180  158 SDPILAKDPDGDSASTLPPPAEKLDKVLTEPRDALKDSPEKLDRPKVEVKDEAQEEPPDLTGGaDHPRPEAASSPKVDPP 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   91 SPPE-------VDHGPEGTLAWDAGDqtLEPGPGGQTPEvvPPDPGAGANSCSPEGlleplAPDSPITLQSPHIEEEETT 163
Cdd:COG5180  238 STSEarsrpatVDAQPEMRPPADAKE--RRRAAIGDTPA--AEPPGLPVLEAGSEP-----QSDAPEAETARPIDVKGVA 308

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413  164 SIATA-------------RRGSPGQEEELPQGQPQS---PNAPPSPSVgetlgdgiNSSQTKPGGSSPPAHPSlPGDGLT 227
Cdd:COG5180  309 SAPPAtrpvrppggardpGTPRPGQPTERPAGVPEAasdAGQPPSAYP--------PAEEAVPGKPLEQGAPR-PGSSGG 379

                        250       260
                 ....*....|....*....|....
gi 12644413  228 AKASEKPPERKRSERVRRAEPPKP 251
Cdd:COG5180  380 DGAPFQPPNGAPQPGLGRRGAPGP 403
PHA03247 PHA03247
large tegument protein UL36; Provisional
 2-260 1.57e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.02  E-value: 1.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413     2 DPSDFPSPFDPLTLPEKPLAGDLPvdmefGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPAGLEKDPGVLDGATELLG 81
Cdd:PHA03247 2604 DRGDPRGPAPPSPLPPDTHAPDPP-----PPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASS 2678

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    82 LGGLLYKAPSPPEVdhGPEGTLAwDAGDQ--TLEPGPGGQTPEVVPPDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEE 159
Cdd:PHA03247 2679 PPQRPRRRAARPTV--GSLTSLA-DPPPPppTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPA 2755

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   160 EETTSIATARRGSPGQEEELPQGQPQSPNAPPSPSVGETLgdgiNSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKR 239
Cdd:PHA03247 2756 RPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESR----ESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPP 2831

                         250       260
                  ....*....|....*....|.
gi 12644413   240 SERVRRAEPPKPEVVDSTESI 260
Cdd:PHA03247 2832 TSAQPTAPPPPPGPPPPSLPL 2852
PHA03247 PHA03247
large tegument protein UL36; Provisional
 3-278 4.39e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.48  E-value: 4.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413     3 PSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGP-SPSSGALDLLDTPAGLEKDPgvldgateLLG 81
Cdd:PHA03247 2763 TAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAvLAPAAALPPAASPAGPLPPP--------TSA 2834

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    82 LGGLLYKAPSPPEVDHGPEGTLAwdAGDQTLEPGPGGQTPEVV--PPDP-----GAGANSCSPEGLlePLAPDSPITLQS 154
Cdd:PHA03247 2835 QPTAPPPPPGPPPPSLPLGGSVA--PGGDVRRRPPSRSPAAKPaaPARPpvrrlARPAVSRSTESF--ALPPDQPERPPQ 2910

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   155 PHIEEEETTSiatarrgSPGQEEELPQGQPQSPNAPPSPSVGET----------------LGDGINSSQTKPGGSSPPAH 218
Cdd:PHA03247 2911 PQAPPPPQPQ-------PQPPPPPQPQPPPPPPPRPQPPLAPTTdpagagepsgavpqpwLGALVPGRVAVPRFRVPQPA 2983

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 12644413   219 PSLPgdglTAKASEKPPERKRSERVR--------RAEP-PKPEVVDSTESIPVSDEDSDA---MVDDPNDED 278
Cdd:PHA03247 2984 PSRE----APASSTPPLTGHSLSRVSswasslalHEETdPPPVSLKQTLWPPDDTEDSDAdslFDSDSERSD 3051
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 34-270 6.39e-06

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 50.69  E-value: 6.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413     34 LLESQTAPTRGWAPPGPSPSSGALDLLD-TPAGlekdpgVLDGATELlglggllykAPSPPEVDHGPEGT----LAWDAG 108
Cdd:pfam05109  448 LPSSTHVPTNLTAPASTGPTVSTADVTSpTPAG------TTSGASPV---------TPSPSPRDNGTESKapdmTSPTSA 512

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    109 DQTLEPGPGGQTPEVVPPDPgagaNSCSPEglLEPLAPDSPITLQSPHIEEEE---TTSIATARRGSPGQEEELPQGQPQ 185
Cdd:pfam05109  513 VTTPTPNATSPTPAVTTPTP----NATSPT--LGKTSPTSAVTTPTPNATSPTpavTTPTPNATIPTLGKTSPTSAVTTP 586

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    186 SPNAPpSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEkppERKRSERVRRAEPPKPEVVDSTESIPVSDE 265
Cdd:pfam05109  587 TPNAT-SPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTG---QHNITSSSTSSMSLRPSSISETLSPSTSDN 662


                   ....*
gi 12644413    266 DSDAM 270
Cdd:pfam05109  663 STSHM 667
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 446-488 7.34e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 7.34e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 12644413    446 LKTNCCDQCGAYIYTKtgsPGPELLFHEGQQKRFCNTTCLGAY 488
Cdd:pfam06467    1 LVKATCWFCKKLIKNK---PTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 348-389 8.43e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 8.43e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 12644413    348 SGKKTCTFCKKEIWNTKDsvVAQTGSGGSFHEFCTSVCLSLY 389
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPT--VIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 586-623 1.24e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.51  E-value: 1.24e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    586 GIHLSCHYCHSLFSGKPE--VLDWQDQVFQFCCRDCCEDF 623
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 674-710 3.05e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 3.05e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    674 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKSKY 710
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
PHA03247 PHA03247
large tegument protein UL36; Provisional
 7-263 3.36e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 3.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413     7 PSPFDPLTlPEKPLAGDLPVdmefgedlleSQTAPTRGWAPPGPSPSSGALDLLDTPAGLEKDPGVLDGATELLGLGGLL 86
Cdd:PHA03247 2734 ALPAAPAP-PAVPAGPATPG----------GPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPW 2802

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    87 YKAPsPPEVDHGPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGllePLAPDSPITLQSPhiEEEETTSIA 166
Cdd:PHA03247 2803 DPAD-PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGG---SVAPGGDVRRRPP--SRSPAAKPA 2876

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   167 TARR-----------GSPGQEEELPQGQPQSPNAPPSPSVGETLGDGINSSQTKP-----GGSSPPAHPSLPGDGLTAKA 230
Cdd:PHA03247 2877 APARppvrrlarpavSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPpppppPRPQPPLAPTTDPAGAGEPS 2956

                         250       260       270
                  ....*....|....*....|....*....|...
gi 12644413   231 SEKPPERKRSERVRRAEPPKPEVVDSTESIPVS 263
Cdd:PHA03247 2957 GAVPQPWLGALVPGRVAVPRFRVPQPAPSREAP 2989
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 88-274 4.41e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 48.06  E-value: 4.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    88 KAPSPPEVDH--GPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGLLEPLAP--DSPITLQSPHIEEEETT 163
Cdd:PRK07764  605 SSGPPEEAARpaAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGgdGWPAKAGGAAPAAPPPA 684

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   164 SIATARRGSPGQEEelPQGQPQSPNAPPSPSVGETLGDGINSSQT-------KPGGSSPPAHPSLPGDGLTAKASEKPPe 236
Cdd:PRK07764  685 PAPAAPAAPAGAAP--AQPAPAPAATPPAGQADDPAAQPPQAAQGasapspaADDPVPLPPEPDDPPDPAGAPAQPPPP- 761

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 12644413   237 rkRSERVRRAEPPKPEVVDSTESiPVSDEDSDAMVDDP 274
Cdd:PRK07764  762 --PAPAPAAAPAAAPPPSPPSEE-EEMAEDDAPSMDDE 796
TRASH smart00746
metallochaperone-like domain;
498-536 5.79e-05

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 41.59  E-value: 5.79e-05
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 12644413     498 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 536
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 102-289 1.04e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 46.30  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   102 TLAWDAGDQ------TLEPGPGGQTpeVVPPDPGAGAnscspegLLEPlAPDSPItlqsPHIeeeetTSIATARRGSPGQ 175
Cdd:NF040712  152 QLSWTAGGSentahwTFDPGAHGGT--VTALDDEARW-------LIDP-DFGRPL----RPL-----ATVPRLAREPADA 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   176 EEELPQGQPQSPNAPPSPSV---GETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKRSERVRRAEPPKPE 252
Cdd:NF040712  213 RPEEVEPAPAAEGAPATDSDpaeAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAA 292

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 12644413   253 vvDSTESIPVSDEDSDAM-VDDPNDEDFVPFRPRRSPR 289
Cdd:NF040712  293 --EPPAPAPAAPAAPAAPeAEEPARPEPPPAPKPKRRR 328
TRASH smart00746
metallochaperone-like domain;
451-492 1.11e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 40.82  E-value: 1.11e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 12644413     451 CDQCGAYIYTKTGspgPELLFHEGQQKRFCNTTCLGAYKKKN 492
Cdd:smart00746    1 CSFCGKDIYNPGT---GIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 715-751 1.79e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 40.05  E-value: 1.79e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    715 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 751
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 106-254 1.80e-04

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 45.53  E-value: 1.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   106 DAGDQTLEPGPGGQTPEVVP-PDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEEEETTSIATARR-----GSPGQEEEL 179
Cdd:NF040712  182 DEARWLIDPDFGRPLRPLATvPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRrragvEQPEDEPVG 261

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 12644413   180 PQGQPQSPNAPPSPSVGETLGDGINSS--QTKPGGSSP--PAHPSLPGDGLTAKASEKPPERKRSERVRRAEPPKPEVV 254
Cdd:NF040712  262 PGAAPAAEPDEATRDAGEPPAPGAAETpeAAEPPAPAPaaPAAPAAPEAEEPARPEPPPAPKPKRRRRRASVPSWDDVL 340
PHA03247 PHA03247
large tegument protein UL36; Provisional
 46-250 3.10e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 3.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    46 APPGPSPSSGALDLLDTPAGlekdPGVLDGATellglggllykAPSPPEVDHGPEGTLAWDAGDQTLEPGPGGQTPEVVP 125
Cdd:PHA03247 2492 AGAAPDPGGGGPPDPDAPPA----PSRLAPAI-----------LPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLP 2556

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   126 PDPgaganscspegllEPLAPDS--PITLQSPHIEEEETTSIAT--------ARRGSPGQEEELPQGQPQSPNAPPSPsv 195
Cdd:PHA03247 2557 PAA-------------PPAAPDRsvPPPRPAPRPSEPAVTSRARrpdappqsARPRAPVDDRGDPRGPAPPSPLPPDT-- 2621

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 12644413   196 getlgdginsSQTKPGGSSPPAHPSLPGDGLTAKASEkPPERKRSERVRRAEPPK 250
Cdd:PHA03247 2622 ----------HAPDPPPPSPSPAANEPDPHPPPTVPP-PERPRDDPAPGRVSRPR 2665
TRASH smart00746
metallochaperone-like domain;
591-627 3.36e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 39.28  E-value: 3.36e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 12644413     591 CHYCHSLFS--GKPEVLDWQDQVFQFCCRDCCEDFKRLR 627
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
679-711 6.01e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.51  E-value: 6.01e-04
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 12644413     679 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKSKYL 711
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 541-578 8.21e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.12  E-value: 8.21e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    541 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 578
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 93-228 1.33e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    93 PEVDHGPEGTLA--------WDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEEEETTS 164
Cdd:PRK07764  365 PSASDDERGLLArlerlerrLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSP 444

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 12644413   165 IATARRGSPGQEEELPQGQPQS-PNAPPSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTA 228
Cdd:PRK07764  445 AGNAPAGGAPSPPPAAAPSAQPaPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDA 509
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 628-664 1.82e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.82e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    628 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 664
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 90-301 1.90e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.85  E-value: 1.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    90 PSPPEVDHGPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGA---GANSCSPEGLLEPLAPDSPITLQSPHIeeeettsia 166
Cdd:PHA03307   30 DAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGpppGPGTEAPANESRSTPTWSLSTLAPASP--------- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   167 tARRGSPGQEEelPQGQPQSPNAPPSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKRS------ 240
Cdd:PHA03307  101 -AREGSPTPPG--PSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQaalpls 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 12644413   241 ---ERVRRAEPPKPEVVDST-----------ESIPVSDEDSDAMVDDPNDEDFvpfrPRRSPRMSLRSSVSQRAG 301
Cdd:PHA03307  178 speETARAPSSPPAEPPPSTppaaasprpprRSSPISASASSPAPAPGRSAAD----DAGASSSDSSSSESSGCG 248
PHA03169 PHA03169
hypothetical protein; Provisional
 31-251 1.93e-03

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 42.27  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    31 GEDLLESQTAPTRGWAP---PGPSPSSGALDLLDTPAGLEKDPGvlDGATELLGlggllykAPSPPEVD-----HGPEGT 102
Cdd:PHA03169   96 GSESVGSPTPSPSGSAEelaSGLSPENTSGSSPESPASHSPPPS--PPSHPGPH-------EPAPPESHnpspnQQPSSF 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   103 LAWDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGLLEPlaPDSPITLQSPHIEEEEttsiaTARRGSPGQEEELPQG 182
Cdd:PHA03169  167 LQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSP--PDEPGEPQSPTPQQAP-----SPNTQQAVEHEDEPTE 239

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 12644413   183 qPQSPNAPPSpsvgetlgdGINSSQTKPGGSSPPAHPslpgDG---LTAKASEKPPERKRSERVRRAEPPKP 251
Cdd:PHA03169  240 -PEREGPPFP---------GHRSHSYTVVGWKPSTRP----GGvpkLCLRCTSHPSHRSRLPEGQQSEDKVP 297
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 98-288 2.13e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 2.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    98 GPEGTLAWDAGDQTLEPGPGGQTPEVVPPDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEEEETTSI----ATARRGSP 173
Cdd:PRK07764  599 GPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGdgwpAKAGGAAP 678

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   174 GQEEELPQGQPQSPNAPPSPS----------VGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKRSERV 243
Cdd:PRK07764  679 AAPPPAPAPAAPAAPAGAAPAqpapapaatpPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQP 758

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 12644413   244 RRAEPPKPEVVDSTESIPVSDEDSDAMVDDpnDEDFVPFRPRRSP 288
Cdd:PRK07764  759 PPPPAPAPAAAPAAAPPPSPPSEEEEMAED--DAPSMDDEDRRDA 801
TRASH smart00746
metallochaperone-like domain;
311-347 3.14e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.59  E-value: 3.14e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 12644413     311 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTFSKKP 347
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 404-440 4.47e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 4.47e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 12644413    404 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 440
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
PHA03247 PHA03247
large tegument protein UL36; Provisional
 40-258 5.84e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 5.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    40 APTRGWAPPGPSPSSGALDLLDTPaglekDPGVLDGATELLGLGgllyKAPSPPEVDHGPEGTLAWDAGDQtlepgpggQ 119
Cdd:PHA03247  270 ETARGATGPPPPPEAAAPNGAAAP-----PDGVWGAALAGAPLA----LPAPPDPPPPAPAGDAEEEDDED--------G 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   120 TPEVVPPDPGAGAN-----------SCSPEGLLEPL-APDSPITLQSPHIEEEETTSIATA--RRGSPGQEEELPQ---- 181
Cdd:PHA03247  333 AMEVVSPLPRPRQHyplgfpkrrrpTWTPPSSLEDLsAGRHHPKRASLPTRKRRSARHAATpfARGPGGDDQTRPAapvp 412

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413   182 GQPQSPNAPPSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPE---RKRSERVRRAEPPKPEVVDSTE 258
Cdd:PHA03247  413 ASVPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPERQPPAPATEPAPDDPDdatRKALDALRERRPPEPPGADLAE 492
TRASH smart00746
metallochaperone-like domain;
546-580 6.64e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.82  E-value: 6.64e-03
                            10        20        30
                    ....*....|....*....|....*....|....*..
gi 12644413     546 CSFCRRSLSDPCYYNKV--DRTVYQFCSPSCWTKFQR 580
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVvnDGKVYYFCSSKCLSKFKK 37
TRASH smart00746
metallochaperone-like domain;
720-755 9.02e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 9.02e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 12644413     720 CHACKRQGKLLETIH---WRGQIRHFCNQQCLLRFYSQQ 755
Cdd:smart00746    1 CSFCGKDIYNPGTGImvvNDGKVYYFCSSKCLSKFKKKR 39
Pro-rich pfam15240
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
 157-252 9.06e-03

Proline-rich protein; This family includes several eukaryotic proline-rich proteins.


Pssm-ID: 464580 [Multi-domain]  Cd Length: 167  Bit Score: 38.48  E-value: 9.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12644413    157 IEEEETTSIATARRGSPGQEEELPQGQPQSPNAPPSPSVGETLG---DGINSSQTKPGGSSPPAHPSLPG-DGLTAKASE 232
Cdd:pfam15240   23 VSQEDSPSLISEEEGQSQQGGQGPQGPPPGGFPPQPPASDDPPGpppPGGPQQPPPQGGKQKPQGPPPQGgPRPPPGKPQ 102

                           90       100
                   ....*....|....*....|
gi 12644413    233 KPPERKRSERVRRAEPPKPE 252
Cdd:pfam15240  103 GPPPQGGNQQQGPPPPGKPQ 122
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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