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Conserved domains on  [gi|74713515|sp|Q7Z4H9|]
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RecName: Full=Protein FAM220A; AltName: Full=STAT3-interacting protein as a repressor

Protein Classification

FAM220 domain-containing protein( domain architecture ID 10634591)

FAM220 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FAM220 pfam15487
FAM220 family; This protein family is a domain of unknown function which is found in ...
2-253 9.21e-101

FAM220 family; This protein family is a domain of unknown function which is found in eukaryotes. Proteins in this family are typically between 217 and 277 amino acids in length. There are two completely conserved residues (S and L) that may be functionally important.


:

Pssm-ID: 464743  Cd Length: 275  Bit Score: 294.79  E-value: 9.21e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74713515     2 RDRRGPLGTCLAQVQQAGGGD----SDKLSCSLKKRMP-EGPWPADAPSWMNKPVVDGNSQS---EALSLEMRKDPSGAG 73
Cdd:pfam15487   1 RDLRDLLCVSRLSVKDSDEEDfsqdSLKLACKLKKRSQkRSPSPSDAPSWTAQPVVDSNKRSrakEAKSLEMKRDQSKAG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74713515    74 LWLHSGGPVLPYVRESVRRNPASAATPSTAVGLFPAP-TECFARVSCSGVEALGRrDWLGGGPRATDGHRGQCPKGEP-- 150
Cdd:pfam15487  81 LLRHSGGKVLPPLKESSRRSSTSAATRVKAVALSPAPkEENFDGILCYIDEAVVS-DWLGRANKSVDNLTDWCHKGDNfv 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74713515   151 -----RVSRLPRHQKV----PEMGSFQDDPPSAFPKGL-GSELEPACLHSILSATLHVYPEVLLSEETKRIFLDRLKPMF 220
Cdd:pfam15487 160 qfahfWLSGLPDHQKLdliqMEVGIIRDEPQSAFPKGLqGTELELSDLRSLLSAILHEYPEVLLNDETKYVFLDYLNPLT 239
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 74713515   221 SKQTIEFKKMLKS---TSDGLQITLGLLALQPFELA 253
Cdd:pfam15487 240 SERTTEYKKLLSDvkcTTDNKQFAQWVLAMRSFALL 275
 
Name Accession Description Interval E-value
FAM220 pfam15487
FAM220 family; This protein family is a domain of unknown function which is found in ...
2-253 9.21e-101

FAM220 family; This protein family is a domain of unknown function which is found in eukaryotes. Proteins in this family are typically between 217 and 277 amino acids in length. There are two completely conserved residues (S and L) that may be functionally important.


Pssm-ID: 464743  Cd Length: 275  Bit Score: 294.79  E-value: 9.21e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74713515     2 RDRRGPLGTCLAQVQQAGGGD----SDKLSCSLKKRMP-EGPWPADAPSWMNKPVVDGNSQS---EALSLEMRKDPSGAG 73
Cdd:pfam15487   1 RDLRDLLCVSRLSVKDSDEEDfsqdSLKLACKLKKRSQkRSPSPSDAPSWTAQPVVDSNKRSrakEAKSLEMKRDQSKAG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74713515    74 LWLHSGGPVLPYVRESVRRNPASAATPSTAVGLFPAP-TECFARVSCSGVEALGRrDWLGGGPRATDGHRGQCPKGEP-- 150
Cdd:pfam15487  81 LLRHSGGKVLPPLKESSRRSSTSAATRVKAVALSPAPkEENFDGILCYIDEAVVS-DWLGRANKSVDNLTDWCHKGDNfv 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74713515   151 -----RVSRLPRHQKV----PEMGSFQDDPPSAFPKGL-GSELEPACLHSILSATLHVYPEVLLSEETKRIFLDRLKPMF 220
Cdd:pfam15487 160 qfahfWLSGLPDHQKLdliqMEVGIIRDEPQSAFPKGLqGTELELSDLRSLLSAILHEYPEVLLNDETKYVFLDYLNPLT 239
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 74713515   221 SKQTIEFKKMLKS---TSDGLQITLGLLALQPFELA 253
Cdd:pfam15487 240 SERTTEYKKLLSDvkcTTDNKQFAQWVLAMRSFALL 275
 
Name Accession Description Interval E-value
FAM220 pfam15487
FAM220 family; This protein family is a domain of unknown function which is found in ...
2-253 9.21e-101

FAM220 family; This protein family is a domain of unknown function which is found in eukaryotes. Proteins in this family are typically between 217 and 277 amino acids in length. There are two completely conserved residues (S and L) that may be functionally important.


Pssm-ID: 464743  Cd Length: 275  Bit Score: 294.79  E-value: 9.21e-101
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74713515     2 RDRRGPLGTCLAQVQQAGGGD----SDKLSCSLKKRMP-EGPWPADAPSWMNKPVVDGNSQS---EALSLEMRKDPSGAG 73
Cdd:pfam15487   1 RDLRDLLCVSRLSVKDSDEEDfsqdSLKLACKLKKRSQkRSPSPSDAPSWTAQPVVDSNKRSrakEAKSLEMKRDQSKAG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74713515    74 LWLHSGGPVLPYVRESVRRNPASAATPSTAVGLFPAP-TECFARVSCSGVEALGRrDWLGGGPRATDGHRGQCPKGEP-- 150
Cdd:pfam15487  81 LLRHSGGKVLPPLKESSRRSSTSAATRVKAVALSPAPkEENFDGILCYIDEAVVS-DWLGRANKSVDNLTDWCHKGDNfv 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74713515   151 -----RVSRLPRHQKV----PEMGSFQDDPPSAFPKGL-GSELEPACLHSILSATLHVYPEVLLSEETKRIFLDRLKPMF 220
Cdd:pfam15487 160 qfahfWLSGLPDHQKLdliqMEVGIIRDEPQSAFPKGLqGTELELSDLRSLLSAILHEYPEVLLNDETKYVFLDYLNPLT 239
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 74713515   221 SKQTIEFKKMLKS---TSDGLQITLGLLALQPFELA 253
Cdd:pfam15487 240 SERTTEYKKLLSDvkcTTDNKQFAQWVLAMRSFALL 275
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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