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Conserved domains on  [gi|81878146|sp|Q8CHW5|]
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RecName: Full=BICD family-like cargo adapter 2; AltName: Full=Bicaudal D-related protein 2; Short=BICD-related protein 2; Short=BICDR-2; AltName: Full=Coiled-coil domain-containing protein 64B

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 53-298 2.03e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 2.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     53 QLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAE---WEARAVELEGDVEALR 129
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELE 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    130 AQLGEQRSERQDSGRERARALGE---LSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAEN 206
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEieeLEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    207 QMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQ 286
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          250
                   ....*....|..
gi 81878146    287 DTEISGASLQTE 298
Cdd:TIGR02168  921 REKLAQLELRLE 932
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 172-491 6.40e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 6.40e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 172 QELQRELDTLRERCQtQALAGAELGARLESLQAEnqMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEH 251
Cdd:COG1196 196 GELERQLEPLERQAE-KAERYRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 252 KLELERARFEAGEALRTLRGLQRRVSELE-----EESRLQDTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPE 326
Cdd:COG1196 273 RLELEELELELEEAQAEEYELLAELARLEqdiarLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 327 TQETSSPQPSIQEEILEppKKRASLSPVEILEEKEAEVARLQDEITLHRTELQTLRDELQRQKELRAQDnpEEALSSALS 406
Cdd:COG1196 353 LEEAEAELAEAEEALLE--AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL--EEELEELEE 428

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 407 DRDEAVNKAMKLSLELSRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSEAAAAPRRAKTR 486
Cdd:COG1196 429 ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508


                ....*
gi 81878146 487 FSLRL 491
Cdd:COG1196 509 GVKAA 513
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 53-298 2.03e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 2.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     53 QLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAE---WEARAVELEGDVEALR 129
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELE 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    130 AQLGEQRSERQDSGRERARALGE---LSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAEN 206
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEieeLEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    207 QMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQ 286
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          250
                   ....*....|..
gi 81878146    287 DTEISGASLQTE 298
Cdd:TIGR02168  921 REKLAQLELRLE 932
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 49-490 1.23e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.23e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  49 DLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEG--DVE 126
Cdd:COG1196 236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERrrELE 315

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 127 ALRAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAEN 206
Cdd:COG1196 316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 207 QMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQ 286
Cdd:COG1196 396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 287 DTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPETQETSSPQPSIQEEILEPPKKRASLSpveileekEAEVAR 366
Cdd:COG1196 476 EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE--------AALAAA 547

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 367 LQDEITLHRTELQTLRDELQRQKELRAqdnpEEALSSALSDRDEAVNKAMKLSLELSRVSLERDSLSRELLRAIRQKVAL 446
Cdd:COG1196 548 LQNIVVEDDEVAAAAIEYLKAAKAGRA----TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*
gi 81878146 447 TQELEAWQDDMQVVIGQQLR-SQRQKELSEAAAAPRRAKTRFSLR 490
Cdd:COG1196 624 GRTLVAARLEAALRRAVTLAgRLREVTLEGEGGSAGGSLTGGSRR 668
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 172-491 6.40e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 6.40e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 172 QELQRELDTLRERCQtQALAGAELGARLESLQAEnqMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEH 251
Cdd:COG1196 196 GELERQLEPLERQAE-KAERYRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 252 KLELERARFEAGEALRTLRGLQRRVSELE-----EESRLQDTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPE 326
Cdd:COG1196 273 RLELEELELELEEAQAEEYELLAELARLEqdiarLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 327 TQETSSPQPSIQEEILEppKKRASLSPVEILEEKEAEVARLQDEITLHRTELQTLRDELQRQKELRAQDnpEEALSSALS 406
Cdd:COG1196 353 LEEAEAELAEAEEALLE--AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL--EEELEELEE 428

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 407 DRDEAVNKAMKLSLELSRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSEAAAAPRRAKTR 486
Cdd:COG1196 429 ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508


                ....*
gi 81878146 487 FSLRL 491
Cdd:COG1196 509 GVKAA 513
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
78-482 2.41e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.42  E-value: 2.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146   78 LRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQrSERQDSGRERARALGELSEQN 157
Cdd:PRK02224 182 LSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEA-DEVLEEHEERREELETLEAEI 260

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  158 LRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQTT 237
Cdd:PRK02224 261 EDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  238 HEELLLLRRERKEHKLELERARFEAGE-------ALRTLRGLQRRVSELEEESRLQDTEISGASLQTELAHSLDSDQDQD 310
Cdd:PRK02224 341 NEEAESLREDADDLEERAEELREEAAEleseleeAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  311 QqvNECGGSQAILSPETQETsspQPSIQE--EILEPPKKRASLSPVE------ILEEKEAEVARLQDEITLHRTELQTLR 382
Cdd:PRK02224 421 R--DELREREAELEATLRTA---RERVEEaeALLEAGKCPECGQPVEgsphveTIEEDRERVEELEAELEDLEEEVEEVE 495

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  383 DELQRQKELRAQdnpeEALSSALSDRDEAVNKAmklsLELSRVSLERDSLSRELLRAirQKVALTQELEAWQDDmqvviG 462
Cdd:PRK02224 496 ERLERAEDLVEA----EDRIERLEERREDLEEL----IAERRETIEEKRERAEELRE--RAAELEAEAEEKREA-----A 560

                        410       420
                 ....*....|....*....|
gi 81878146  463 QQLRSQRQKELSEAAAAPRR 482
Cdd:PRK02224 561 AEAEEEAEEAREEVAELNSK 580
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 50-502 4.13e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 40.10  E-value: 4.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     50 LALQLQQKEKDLLLAAELGKMLLERN-------EELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELE 122
Cdd:pfam15921  382 LLADLHKREKELSLEKEQNKRLWDRDtgnsitiDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLE 461

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    123 gDVEALRAQLGEQRSERQDSGRE--RARALGELSEQNLR-LSQQLAQASRTEQELQRELDTLRERCQTQALAGAEL---G 196
Cdd:pfam15921  462 -KVSSLTAQLESTKEMLRKVVEEltAKKMTLESSERTVSdLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLkneG 540

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    197 ARLESLQAENQMLQDRRQDLEAQIRGLREEVDK-----GQNRlQTTHEELLLLRRERKE---HKLELERARFEAGEALRT 268
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEKDKVIEILRQQIENmtqlvGQHG-RTAGAMQVEKAQLEKEindRRLELQEFKILKDKKDAK 619

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    269 LRGLQRRVSELEEE---------SRLQDTEisgaSLQTELAHSLDSDQDQDQQVNECGGSQAILS------PETQETSSP 333
Cdd:pfam15921  620 IRELEARVSDLELEkvklvnagsERLRAVK----DIKQERDQLLNEVKTSRNELNSLSEDYEVLKrnfrnkSEEMETTTN 695

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    334 QPSIQEEIL--EPPKKRASLSPVEILEEKEAEVAR-LQDEITLHRTELQTLRDELQRQkelraqdnpEEALSSALSDRDE 410
Cdd:pfam15921  696 KLKMQLKSAqsELEQTRNTLKSMEGSDGHAMKVAMgMQKQITAKRGQIDALQSKIQFL---------EEAMTNANKEKHF 766

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    411 AVNKAMKLSLELSRVSLERDSLSREL------LRAIRQKVAlTQELEAWQDDMQVVIGQQLrSQRQKELSEaaaaprRAK 484
Cdd:pfam15921  767 LKEEKNKLSQELSTVATEKNKMAGELevlrsqERRLKEKVA-NMEVALDKASLQFAECQDI-IQRQEQESV------RLK 838

                          490
                   ....*....|....*...
gi 81878146    485 TRFSLRLGSGQSGGFLSN 502
Cdd:pfam15921  839 LQHTLDVKELQGPGYTSN 856
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 53-298 2.03e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 2.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     53 QLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAE---WEARAVELEGDVEALR 129
Cdd:TIGR02168  681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELE 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    130 AQLGEQRSERQDSGRERARALGE---LSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAEN 206
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEieeLEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    207 QMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQ 286
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          250
                   ....*....|..
gi 81878146    287 DTEISGASLQTE 298
Cdd:TIGR02168  921 REKLAQLELRLE 932
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 49-490 1.23e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.23e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  49 DLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEG--DVE 126
Cdd:COG1196 236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERrrELE 315

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 127 ALRAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAEN 206
Cdd:COG1196 316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 207 QMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQ 286
Cdd:COG1196 396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 287 DTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPETQETSSPQPSIQEEILEPPKKRASLSpveileekEAEVAR 366
Cdd:COG1196 476 EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE--------AALAAA 547

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 367 LQDEITLHRTELQTLRDELQRQKELRAqdnpEEALSSALSDRDEAVNKAMKLSLELSRVSLERDSLSRELLRAIRQKVAL 446
Cdd:COG1196 548 LQNIVVEDDEVAAAAIEYLKAAKAGRA----TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLL 623

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*
gi 81878146 447 TQELEAWQDDMQVVIGQQLR-SQRQKELSEAAAAPRRAKTRFSLR 490
Cdd:COG1196 624 GRTLVAARLEAALRRAVTLAgRLREVTLEGEGGSAGGSLTGGSRR 668
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 172-491 6.40e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 6.40e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 172 QELQRELDTLRERCQtQALAGAELGARLESLQAEnqMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEH 251
Cdd:COG1196 196 GELERQLEPLERQAE-KAERYRELKEELKELEAE--LLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 252 KLELERARFEAGEALRTLRGLQRRVSELE-----EESRLQDTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPE 326
Cdd:COG1196 273 RLELEELELELEEAQAEEYELLAELARLEqdiarLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 327 TQETSSPQPSIQEEILEppKKRASLSPVEILEEKEAEVARLQDEITLHRTELQTLRDELQRQKELRAQDnpEEALSSALS 406
Cdd:COG1196 353 LEEAEAELAEAEEALLE--AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL--EEELEELEE 428

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 407 DRDEAVNKAMKLSLELSRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSEAAAAPRRAKTR 486
Cdd:COG1196 429 ALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508


                ....*
gi 81878146 487 FSLRL 491
Cdd:COG1196 509 GVKAA 513
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 76-423 7.37e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 7.37e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     76 EELRRQLETLNTQhLEHEERLQQENHELRrglAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERARALGELSE 155
Cdd:TIGR02168  196 NELERQLKSLERQ-AEKAERYKELKAELR---ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    156 QNLRLSqqlaQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQ 235
Cdd:TIGR02168  272 LRLEVS----ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    236 TTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQDTEISGA-SLQTELAHSLDSDQDQDQQVN 314
Cdd:TIGR02168  348 ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLeARLERLEDRRERLQQEIEELL 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    315 ecggsQAILSPETQETSSPQPSIQEEILEppkkraslsPVEILEEKEAEVARLQDEITLHRTELQTLRDELQRqkeLRAQ 394
Cdd:TIGR02168  428 -----KKLEEAELKELQAELEELEEELEE---------LQEELERLEEALEELREELEEAEQALDAAERELAQ---LQAR 490

                          330       340
                   ....*....|....*....|....*....
gi 81878146    395 DNPEEALSSALSDRDEAVNKAMKLSLELS 423
Cdd:TIGR02168  491 LDSLERLQENLEGFSEGVKALLKNQSGLS 519
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 74-498 1.37e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 1.37e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  74 RNEELRRQLETLNTQHLEHEERLQQENHELRRgLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERARALGEL 153
Cdd:COG1196 219 KEELKELEAELLLLKLRELEAELEELEAELEE-LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL 297

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 154 SeqnlRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNR 233
Cdd:COG1196 298 A----RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 234 LQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQDTEISGASLQTELAHSLDSDQDQDQQV 313
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 314 NECGGSQAILSPETQETSSPQPSIQEEILEPPKKRA-----SLSPVEILEEKEAEVARLQDEITLHRTELQTLRDELQRQ 388
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAaarllLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 389 KELR-AQDNPEEALSSALSDRDEAVNKAMKLSL-----------ELSRVSLERDSLSRELLRAIRQKVALTQELEAWQDD 456
Cdd:COG1196 534 AAYEaALEAALAAALQNIVVEDDEVAAAAIEYLkaakagratflPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                       410       420       430       440
                ....*....|....*....|....*....|....*....|..
gi 81878146 457 MQVVIGQQLRSQRQKELSEAAAAPRRAKTRFSLRLGSGQSGG 498
Cdd:COG1196 614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 76-483 6.00e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 6.00e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  76 EELRRQLETLNTQhleheerlqqenhelrRGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDsgreraRALGELSE 155
Cdd:COG1196 196 GELERQLEPLERQ----------------AEKAERYRELKEELKELEAELLLLKLRELEAELEELE------AELEELEA 253

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 156 QNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQ 235
Cdd:COG1196 254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 236 TTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQDTEISGASLQTELAHSLDSDQDQDQQVNE 315
Cdd:COG1196 334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 316 cggsQAILSPETQETSSPQPSIQEEILEPPKKRASLSPVEILEEKEAEVARLQDEITLHRTELQTLRDELQRQKELRAQD 395
Cdd:COG1196 414 ----ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 396 NPEEALSSALSDRDEAVNKAMKLSLELSRVSLERDSLSRELLRAIRQKVALTQELEAWqddMQVVIGQQLRSQRQKELSE 475
Cdd:COG1196 490 AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA---LQNIVVEDDEVAAAAIEYL 566


                ....*...
gi 81878146 476 AAAAPRRA 483
Cdd:COG1196 567 KAAKAGRA 574
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
53-234 1.36e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.62  E-value: 1.36e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146   53 QLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELR-RGLAARGAEWEARAVELE---GDVEAL 128
Cdd:COG4913  611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDvASAEREIAELEAELERLDassDDLAAL 690

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  129 RAQLGEQRSERQDSGRERARALGELSeqnlRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAElgARLESLQAENQm 208
Cdd:COG4913  691 EEQLEELEAELEELEEELDELKGEIG----RLEKELEQAEEELDELQDRLEAAEDLARLELRALLE--ERFAAALGDAV- 763

                        170       180
                 ....*....|....*....|....*.
gi 81878146  209 LQDRRQDLEAQIRGLREEVDKGQNRL 234
Cdd:COG4913  764 ERELRENLEERIDALRARLNRAEEEL 789
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 50-486 1.45e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.45e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  50 LALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEwEARAVELEGDVEALR 129
Cdd:COG1196 328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA-LRAAAELAAQLEELE 406

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 130 AQLG--EQRSERQDSGRER--------ARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARL 199
Cdd:COG1196 407 EAEEalLERLERLEEELEEleealaelEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 200 ESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSEL 279
Cdd:COG1196 487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 280 EEESRLQDTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPETQETSSPQPSIQEEILEPPKKRASLSPVEILEE 359
Cdd:COG1196 567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRL 646

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 360 KEAEVARLQDEITLHRTELQTLRDELQRQKELRAQDNPEEALSSALSDRDEAVNKAMKLSLELSRVSLERDSLSRELLRA 439
Cdd:COG1196 647 REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAL 726

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*..
gi 81878146 440 IRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSEAAAAPRRAKTR 486
Cdd:COG1196 727 EEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 70-386 1.71e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 1.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     70 MLLERNEELRRQLETLnTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERARA 149
Cdd:TIGR02169  678 RLRERLEGLKRELSSL-QSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    150 LGELSEQNLRLSQQLAQASRTE---------------QELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQ 214
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEealndlearlshsriPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ 836

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    215 -------DLEAQIRGLREEVDKGQNRLQttheellllrrerkEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQD 287
Cdd:TIGR02169  837 elqeqriDLKEQIKSIEKEIENLNGKKE--------------ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE 902

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    288 TEISGASLQTELA-HSLDSDQDQDQQVNECGGSQAILSPETQETSSPQPS---IQEEILEPPKKRASLSPVEILEEKE-A 362
Cdd:TIGR02169  903 RKIEELEAQIEKKrKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSledVQAELQRVEEEIRALEPVNMLAIQEyE 982

                          330       340
                   ....*....|....*....|....
gi 81878146    363 EVARLQDEITLHRTELQTLRDELQ 386
Cdd:TIGR02169  983 EVLKRLDELKEKRAKLEEERKAIL 1006
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 76-291 9.45e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 9.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     76 EELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERARALGELSE 155
Cdd:TIGR02169  254 EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    156 qnlrlsqqlaqasrteqeLQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQ 235
Cdd:TIGR02169  334 ------------------LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 81878146    236 TTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQDTEIS 291
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIK 451
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 53-300 1.18e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.60  E-value: 1.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     53 QLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELR------RGLAARGAEWEARAVELEGDVE 126
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYalaneiSRLEQQKQILRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    127 ALRAQLGEQRSERQDSGRERAR---ALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQ 203
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAEleeKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    204 AENQMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEAlrTLRGLQRRVSELEEEs 283
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEE--ALEELREELEEAEQA- 476

                          250
                   ....*....|....*..
gi 81878146    284 rLQDTEISGASLQTELA 300
Cdd:TIGR02168  477 -LDAAERELAQLQARLD 492
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 61-283 2.04e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.04e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  61 LLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHElRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQ 140
Cdd:COG4942   8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKE-EKALLKQLAALERRIAALARRIRALEQELAALEAELA 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 141 DSGRERARALGELSEQNLRLSQQLAQASRTEQ--------------ELQRELDTLRERCQTQALAGAELGARLESLQAEN 206
Cdd:COG4942  87 ELEKEIAELRAELEAQKEELAELLRALYRLGRqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALR 166

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 81878146 207 QMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEES 283
Cdd:COG4942 167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 49-236 2.29e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.29e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  49 DLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVEL----EGD 124
Cdd:COG4942  52 ALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALllspEDF 131

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 125 VEALRAQ--LGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESL 202
Cdd:COG4942 132 LDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAEL 211

                       170       180       190
                ....*....|....*....|....*....|....
gi 81878146 203 QAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQT 236
Cdd:COG4942 212 AAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
78-482 2.41e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.42  E-value: 2.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146   78 LRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQrSERQDSGRERARALGELSEQN 157
Cdd:PRK02224 182 LSDQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEA-DEVLEEHEERREELETLEAEI 260

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  158 LRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQTT 237
Cdd:PRK02224 261 EDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  238 HEELLLLRRERKEHKLELERARFEAGE-------ALRTLRGLQRRVSELEEESRLQDTEISGASLQTELAHSLDSDQDQD 310
Cdd:PRK02224 341 NEEAESLREDADDLEERAEELREEAAEleseleeAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  311 QqvNECGGSQAILSPETQETsspQPSIQE--EILEPPKKRASLSPVE------ILEEKEAEVARLQDEITLHRTELQTLR 382
Cdd:PRK02224 421 R--DELREREAELEATLRTA---RERVEEaeALLEAGKCPECGQPVEgsphveTIEEDRERVEELEAELEDLEEEVEEVE 495

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  383 DELQRQKELRAQdnpeEALSSALSDRDEAVNKAmklsLELSRVSLERDSLSRELLRAirQKVALTQELEAWQDDmqvviG 462
Cdd:PRK02224 496 ERLERAEDLVEA----EDRIERLEERREDLEEL----IAERRETIEEKRERAEELRE--RAAELEAEAEEKREA-----A 560

                        410       420
                 ....*....|....*....|
gi 81878146  463 QQLRSQRQKELSEAAAAPRR 482
Cdd:PRK02224 561 AEAEEEAEEAREEVAELNSK 580
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 76-293 3.87e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.68  E-value: 3.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     76 EELRRQLETLNTQHLEHEE--RLQQENHELR-RGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERARALGE 152
Cdd:TIGR02169  194 DEKRQQLERLRREREKAERyqALLKEKREYEgYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQL 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    153 LSEQNLR------------------LSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQ 214
Cdd:TIGR02169  274 LEELNKKikdlgeeeqlrvkekigeLEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD 353

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 81878146    215 DLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQDTEISGA 293
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGI 432
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 50-235 4.22e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.67  E-value: 4.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     50 LALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQqenhELRRGLAARGAEWEARA---VELEGDVE 126
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE----ELESRLEELEEQLETLRskvAQLELQIA 396

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    127 ALRAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAqasrteQELQRELDTLRERCQTQALAGAELGARLESLQAEN 206
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL------KELQAELEELEEELEELQEELERLEEALEELREEL 470

                          170       180
                   ....*....|....*....|....*....
gi 81878146    207 QMLQDRRQDLEAQIRGLREEVDKGQNRLQ 235
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQE 499
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
71-282 5.78e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 5.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146   71 LLERNEELRRQLETLNTQHLEHEERLQQENHELR-RGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDsgreraRA 149
Cdd:COG4913  223 TFEAADALVEHFDDLERAHEALEDAREQIELLEPiRELAERYAAARERLAELEYLRAALRLWFAQRRLELLE------AE 296

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  150 LGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQAlagaelGARLESLQAENQMLQD-------RRQDLEAQIRG 222
Cdd:COG4913  297 LEELRAELARLEAELERLEARLDALREELDELEAQIRGNG------GDRLEQLEREIERLEReleererRRARLEALLAA 370

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  223 LREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRglqRRVSELEEE 282
Cdd:COG4913  371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR---RELRELEAE 427
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
29-235 1.13e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 1.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146   29 FVLERRDSFLGGGPGPEEPEDL------ALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHE 102
Cdd:COG4913  216 YMLEEPDTFEAADALVEHFDDLeraheaLEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEA 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  103 LRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERaraLGELSEQNLRLSQQLAQASRTEQELQRELDTLR 182
Cdd:COG4913  296 ELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDR---LEQLEREIERLERELEERERRRARLEALLAALG 372

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 81878146  183 ERCQTQALAGAELG----ARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQ 235
Cdd:COG4913  373 LPLPASAEEFAALRaeaaALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIA 429
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 37-265 2.50e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 2.50e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  37 FLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRgLAARGAEWEA 116
Cdd:COG4942  12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAA-LEAELAELEK 90

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 117 RAVELEGDVEALRAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELG 196
Cdd:COG4942  91 EIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 81878146 197 ARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEA 265
Cdd:COG4942 171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 115-475 1.34e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    115 EARAVELEGDVEALRAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAE 194
Cdd:TIGR02168  644 GYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    195 LGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQR 274
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    275 RVSELEEEsrLQDTEISGASLQTELAHSLDSDQDQDQQVNECggsqailspetqetsspqpsiqeeileppkkraslspV 354
Cdd:TIGR02168  804 ALDELRAE--LTLLNEEAANLRERLESLERRIAATERRLEDL-------------------------------------E 844

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    355 EILEEKEAEVARLQDEITlhrtELQTLRDELQRQkelraqdnpeeaLSSALSDRDEAVNKAMKLSLELSRVSLERDSLSR 434
Cdd:TIGR02168  845 EQIEELSEDIESLAAEIE----ELEELIEELESE------------LEALLNERASLEEALALLRSELEELSEELRELES 908

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 81878146    435 ELLRAIRQKVALTQELEAWQDDMQVVigQQLRSQRQKELSE 475
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGL--EVRIDNLQERLSE 947
mukB PRK04863
chromosome partition protein MukB;
73-221 3.24e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 3.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    73 ERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAA-RGAEWEARAVElegDVEALRAQLGEQR--SERQDSGRERARA 149
Cdd:PRK04863  307 YRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTAlRQQEKIERYQA---DLEELEERLEEQNevVEEADEQQEENEA 383

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146   150 LGELSEQN-LRLSQQLA-----------QASRTEQELQReLDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLE 217
Cdd:PRK04863  384 RAEAAEEEvDELKSQLAdyqqaldvqqtRAIQYQQAVQA-LERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSLE 462


                  ....
gi 81878146   218 AQIR 221
Cdd:PRK04863  463 QKLS 466
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
56-236 3.81e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 3.81e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  56 QKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAArgaeweARAVELEGDVEALRAQLGEQ 135
Cdd:COG3206 202 RQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA------LPELLQSPVIQQLRAQLAEL 275

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 136 RserqdsgRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQAlagAELGARLESLQAENQMLQDRRQD 215
Cdd:COG3206 276 E-------AELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAEL---EALQAREASLQAQLAQLEARLAE 345

                       170       180
                ....*....|....*....|....
gi 81878146 216 L---EAQIRGLREEVDKGQNRLQT 236
Cdd:COG3206 346 LpelEAELRRLEREVEVARELYES 369
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
49-184 7.26e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 7.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146   49 DLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEAL 128
Cdd:COG4913  299 ELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPAS 378

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 81878146  129 RAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRER 184
Cdd:COG4913  379 AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 51-235 8.20e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 8.20e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  51 ALQLQQKEKDLLLAAELGKMLLERNEELRRQL--ETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEAL 128
Cdd:COG1196 591 ALARGAIGAAVDLVASDLREADARYYVLGDTLlgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 129 RAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQM 208
Cdd:COG1196 671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750

                       170       180
                ....*....|....*....|....*..
gi 81878146 209 LQDRRQDLEAQIRGLREEVDKGQNRLQ 235
Cdd:COG1196 751 EALEELPEPPDLEELERELERLEREIE 777
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 76-167 1.73e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.09  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    76 EELRRQLETLNTQhLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERARALGELSE 155
Cdd:PRK11448  145 HALQQEVLTLKQQ-LELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQKRKEITD 223

                          90       100
                  ....*....|....*....|....
gi 81878146   156 Q---NLRLS---------QQLAQA 167
Cdd:PRK11448  224 QaakRLELSeeetrilidQQLRKA 247
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 49-491 3.25e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.43  E-value: 3.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     49 DLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRgLAARGAEWEARAVELEGDVEAL 128
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-LELQIASLNNEIERLEARLERL 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    129 RAQLGEQRSERQDSGRERARA-LGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQ 207
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    208 MLQDRRQDLEAQIRGLREEVDKgQNRLQTTHEELLLLRRERKEHKLELERARFEAGEAL--RTLRGLQRRVSELEEESR- 284
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKN-QSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVvvENLNAAKKAIAFLKQNELg 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    285 ----LQDTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPETQE-------TSSPQPSIQEEILEPPKKR----- 348
Cdd:TIGR02168  572 rvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvVDDLDNALELAKKLRPGYRivtld 651

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    349 ----------------ASLSPVEI---LEEKEAEVARLQDEITLHRTELQTLRDELQR-QKELRAQDNPEEALSSALSDR 408
Cdd:TIGR02168  652 gdlvrpggvitggsakTNSSILERrreIEELEEKIEELEEKIAELEKALAELRKELEElEEELEQLRKELEELSRQISAL 731

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    409 DEavnKAMKLSLELSRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQ-QLRSQRQKELSEAAAAPRRAKTRF 487
Cdd:TIGR02168  732 RK---DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEiEELEAQIEQLKEELKALREALDEL 808


                   ....
gi 81878146    488 SLRL 491
Cdd:TIGR02168  809 RAEL 812
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 50-502 4.13e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 40.10  E-value: 4.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146     50 LALQLQQKEKDLLLAAELGKMLLERN-------EELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELE 122
Cdd:pfam15921  382 LLADLHKREKELSLEKEQNKRLWDRDtgnsitiDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLE 461

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    123 gDVEALRAQLGEQRSERQDSGRE--RARALGELSEQNLR-LSQQLAQASRTEQELQRELDTLRERCQTQALAGAEL---G 196
Cdd:pfam15921  462 -KVSSLTAQLESTKEMLRKVVEEltAKKMTLESSERTVSdLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLkneG 540

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    197 ARLESLQAENQMLQDRRQDLEAQIRGLREEVDK-----GQNRlQTTHEELLLLRRERKE---HKLELERARFEAGEALRT 268
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEKDKVIEILRQQIENmtqlvGQHG-RTAGAMQVEKAQLEKEindRRLELQEFKILKDKKDAK 619

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    269 LRGLQRRVSELEEE---------SRLQDTEisgaSLQTELAHSLDSDQDQDQQVNECGGSQAILS------PETQETSSP 333
Cdd:pfam15921  620 IRELEARVSDLELEkvklvnagsERLRAVK----DIKQERDQLLNEVKTSRNELNSLSEDYEVLKrnfrnkSEEMETTTN 695

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    334 QPSIQEEIL--EPPKKRASLSPVEILEEKEAEVAR-LQDEITLHRTELQTLRDELQRQkelraqdnpEEALSSALSDRDE 410
Cdd:pfam15921  696 KLKMQLKSAqsELEQTRNTLKSMEGSDGHAMKVAMgMQKQITAKRGQIDALQSKIQFL---------EEAMTNANKEKHF 766

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146    411 AVNKAMKLSLELSRVSLERDSLSREL------LRAIRQKVAlTQELEAWQDDMQVVIGQQLrSQRQKELSEaaaaprRAK 484
Cdd:pfam15921  767 LKEEKNKLSQELSTVATEKNKMAGELevlrsqERRLKEKVA-NMEVALDKASLQFAECQDI-IQRQEQESV------RLK 838

                          490
                   ....*....|....*...
gi 81878146    485 TRFSLRLGSGQSGGFLSN 502
Cdd:pfam15921  839 LQHTLDVKELQGPGYTSN 856
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
72-238 4.28e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 39.75  E-value: 4.28e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  72 LERNEELRRQLETLNTQHleheERLQQENHELRRGLaaRGAEWEARAVELEGDVEALRAQLgEQRSERQDSGRERARALG 151
Cdd:COG4717  87 EEEYAELQEELEELEEEL----EELEAELEELREEL--EKLEKLLQLLPLYQELEALEAEL-AELPERLEELEERLEELR 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 152 ELSEQNLRLSQQLAQASRTEQELQRELDTLRERcqtqalAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQ 231
Cdd:COG4717 160 ELEEELEELEAELAELQEELEELLEQLSLATEE------ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE 233


                ....*..
gi 81878146 232 NRLQTTH 238
Cdd:COG4717 234 NELEAAA 240
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
143-287 4.82e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.90  E-value: 4.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  143 GRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQT-QALAG---------------AELGARLESLQAEN 206
Cdd:COG4913  605 GFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAlQRLAEyswdeidvasaereiAELEAELERLDASS 684

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  207 ---QMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLrgLQRRVSELEEES 283
Cdd:COG4913  685 ddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDA 762


                 ....
gi 81878146  284 RLQD 287
Cdd:COG4913  763 VERE 766
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
49-176 5.63e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 38.88  E-value: 5.63e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  49 DLALQLQQKEKDLLlAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRR--GLAARGAEWEARAVELEGDVE 126
Cdd:COG1566  80 DLQAALAQAEAQLA-AAEAQLARLEAELGAEAEIAAAEAQLAAAQAQLDLAQRELERyqALYKKGAVSQQELDEARAALD 158

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 81878146 127 ALRAQLGEQRSERQDSgRERARALGELSEQNLRLSQQLAQASRTEQELQR 176
Cdd:COG1566 159 AAQAQLEAAQAQLAQA-QAGLREEEELAAAQAQVAQAEAALAQAELNLAR 207
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 50-371 7.82e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.15  E-value: 7.82e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146  50 LALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQ----QENHELRRGLAARGAEWEARAVELEGDV 125
Cdd:COG1196 461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvkaALLLAGLRGLAGAVAVLIGVEAAYEAAL 540

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 126 EALRAQLGEQRSERQDsgRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAE 205
Cdd:COG1196 541 EAALAAALQNIVVEDD--EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL 618

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 206 NQMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRL 285
Cdd:COG1196 619 GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA 698

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81878146 286 QDTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPETQEtsspqpsiQEEILEPPKKRASLSPVEILEEKEAEVA 365
Cdd:COG1196 699 LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL--------EEEELLEEEALEELPEPPDLEELERELE 770


                ....*.
gi 81878146 366 RLQDEI 371
Cdd:COG1196 771 RLEREI 776
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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