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Conserved domains on  [gi|32469819|sp|Q8X6C0|]
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RecName: Full=Putative carbamoyltransferase YgeW

Protein Classification

knotted carbamoyltransferase YgeW( domain architecture ID 11482624)

knotted carbamoyltransferase YgeW is a putative carbamoyltransferase, but no activity can be detected with allantoin or 25 other related compounds, including 20 naturally occurring amino acids, N-acetyl-L-ornithine, N-succinyl-L-ornithine, L-ornithine, oxamate, beta-alanine and putrescine

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
2-396 0e+00

aspartate/ornithine carbamoyltransferase family protein; Validated


:

Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 863.28  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819    2 MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASA 81
Cdd:PRK07200   1 MKTVNELIKDLNSLTSHMHEKDFLLTWEKTPDELKAVLDVADALRALREENISTKVFNSGLGISVFRDNSTRTRFSYASA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   82 LNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC 161
Cdd:PRK07200  81 CNLLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMREVGAAVDDGYKQGVLPQRPTLVNLQC 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  162 DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAK 241
Cdd:PRK07200 161 DIDHPTQSMADLLHLIEHFGGLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLMPEVVEVAK 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTR 321
Cdd:PRK07200 241 KNAKASGGSFRQVNSMEEAFKDADIVYPKSWAPYKVMEERTELYRAGDHEGIKALEKELLAQNAQHKDWHCTEEMMKLTK 320
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 32469819  322 DGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK 396
Cdd:PRK07200 321 DGKALYMHCLPADISGVSCKEGEVTESVFDRYRIALYKEASWKPYIIAAMIFLRKYKNPGALLEQLLKEAQPRVK 395
 
Name Accession Description Interval E-value
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
2-396 0e+00

aspartate/ornithine carbamoyltransferase family protein; Validated


Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 863.28  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819    2 MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASA 81
Cdd:PRK07200   1 MKTVNELIKDLNSLTSHMHEKDFLLTWEKTPDELKAVLDVADALRALREENISTKVFNSGLGISVFRDNSTRTRFSYASA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   82 LNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC 161
Cdd:PRK07200  81 CNLLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMREVGAAVDDGYKQGVLPQRPTLVNLQC 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  162 DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAK 241
Cdd:PRK07200 161 DIDHPTQSMADLLHLIEHFGGLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLMPEVVEVAK 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTR 321
Cdd:PRK07200 241 KNAKASGGSFRQVNSMEEAFKDADIVYPKSWAPYKVMEERTELYRAGDHEGIKALEKELLAQNAQHKDWHCTEEMMKLTK 320
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 32469819  322 DGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK 396
Cdd:PRK07200 321 DGKALYMHCLPADISGVSCKEGEVTESVFDRYRIALYKEASWKPYIIAAMIFLRKYKNPGALLEQLLKEAQPRVK 395
ygeW TIGR03316
knotted carbamoyltransferase YgeW; Members of this protein family include the ygeW gene ...
5-394 0e+00

knotted carbamoyltransferase YgeW; Members of this protein family include the ygeW gene product of Escherichia coli. The function is unknown. Members show homology to ornithine carbamoyltransferase (TIGR00658) and aspartate carbamoyltransferase (carbamoyltransferase), and therefore may belong to the carbamoyltransferases in function. Members often are found in a large, conserved genomic region associated with selenium-dependent molybdenum hydroxylases.


Pssm-ID: 274517 [Multi-domain]  Cd Length: 391  Bit Score: 722.28  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819     5 VNELIKDINSL-TSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALN 83
Cdd:TIGR03316   1 IKEYIEKLNKLdFKKMYNNDFFLTWEKTDDELKAVFTVADALRALRENNISTKIFDSGLGISLFRDNSTRTRFSFASACN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819    84 LLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQCDI 163
Cdd:TIGR03316  81 LLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMHEVSDSVQEGYKDGVLEQRPTLVNLQCDI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   164 DHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNN 243
Cdd:TIGR03316 161 DHPTQSMADMLHLIHEFGGIENLKGKKVAMTWAYSPSYGKPLSVPQGVIGLFTRFGMDVVLAHPEGYEVMPEVEEVAKKN 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   244 AKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDG 323
Cdd:TIGR03316 241 AAESGGSFTKTNSMAEAFKDADIVYPKSWAPFAAMEKRTNLYGEGDFAGIDALEKELLAQNATHKDWECTEELMKTTKDG 320
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 32469819   324 EALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQER 394
Cdd:TIGR03316 321 KALYLHCLPADITGVSCEEGEVEASVFDRYRVPLYKEASYKPYIIAAMIFLSKVKNPAATLEKLEEKATPR 391
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
17-373 2.83e-105

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 312.76  E-value: 2.83e-105
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  17 SHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGK 96
Cdd:COG0078   1 TNLKGRHFLSLLDLTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPGD 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  97 SQIAHGETVRETANMISFCADAIGIRddmylGAGNAYMREVGAAlddgykqgvlpQRPALVNLQCDIDHPTQSMADLAWL 176
Cdd:COG0078  81 SQLGRGESIKDTARVLSRYVDGIMIR-----TFGHETLEELAKY-----------AGVPVINGLTDLFHPCQALADLLTI 144
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819 177 REHFGSlenLKGKKIAMTWAyspsygkPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTS 256
Cdd:COG0078 145 REHFGK---LKGLKVAYVGD-------GNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHD 214
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819 257 MEEAFKDADIVYPKSWAPykvMEQrtellrandheglkalEKQCLAQNAQHKDWHCTEEMMELTRDgEALYMHCLPADIs 336
Cdd:COG0078 215 PAEAVKGADVVYTDVWVS---MGQ----------------EEEAEERIKAFKPYQVNEELMALAKP-DAIFMHCLPAHR- 273
                       330       340       350
                ....*....|....*....|....*....|....*..
gi 32469819 337 gvsckEGEVTEGVFEKYRIATYKEASWKPYIIAAMIL 373
Cdd:COG0078 274 -----GEEVTDEVIDGPQSVVFDEAENRLHAQKALLA 305
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
190-374 2.46e-36

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 129.65  E-value: 2.46e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   190 KIAMTWayspsyGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYP 269
Cdd:pfam00185   1 KIAYVG------DGHNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKSGGSIEITDDPAEAVKGADVVYT 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   270 KSWAPykvMEQrtellrandheglkalEKQCLAQNAQHKDWHCTEEMMELTRDgEALYMHCLPADisgvscKEGEVTEGV 349
Cdd:pfam00185  75 DVWQS---MGQ----------------EKEREERLKAFKPYQVNEELMKLAKK-DAIFMHCLPAH------RGEEVTDDV 128
                         170       180
                  ....*....|....*....|....*
gi 32469819   350 FEKYRIATYKEASWKPYIIAAMILS 374
Cdd:pfam00185 129 FDGPRSVVFDQAENRLHAQKALLAL 153
 
Name Accession Description Interval E-value
PRK07200 PRK07200
aspartate/ornithine carbamoyltransferase family protein; Validated
2-396 0e+00

aspartate/ornithine carbamoyltransferase family protein; Validated


Pssm-ID: 235961 [Multi-domain]  Cd Length: 395  Bit Score: 863.28  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819    2 MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASA 81
Cdd:PRK07200   1 MKTVNELIKDLNSLTSHMHEKDFLLTWEKTPDELKAVLDVADALRALREENISTKVFNSGLGISVFRDNSTRTRFSYASA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   82 LNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC 161
Cdd:PRK07200  81 CNLLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMREVGAAVDDGYKQGVLPQRPTLVNLQC 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  162 DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAK 241
Cdd:PRK07200 161 DIDHPTQSMADLLHLIEHFGGLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLMPEVVEVAK 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTR 321
Cdd:PRK07200 241 KNAKASGGSFRQVNSMEEAFKDADIVYPKSWAPYKVMEERTELYRAGDHEGIKALEKELLAQNAQHKDWHCTEEMMKLTK 320
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 32469819  322 DGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK 396
Cdd:PRK07200 321 DGKALYMHCLPADISGVSCKEGEVTESVFDRYRIALYKEASWKPYIIAAMIFLRKYKNPGALLEQLLKEAQPRVK 395
ygeW TIGR03316
knotted carbamoyltransferase YgeW; Members of this protein family include the ygeW gene ...
5-394 0e+00

knotted carbamoyltransferase YgeW; Members of this protein family include the ygeW gene product of Escherichia coli. The function is unknown. Members show homology to ornithine carbamoyltransferase (TIGR00658) and aspartate carbamoyltransferase (carbamoyltransferase), and therefore may belong to the carbamoyltransferases in function. Members often are found in a large, conserved genomic region associated with selenium-dependent molybdenum hydroxylases.


Pssm-ID: 274517 [Multi-domain]  Cd Length: 391  Bit Score: 722.28  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819     5 VNELIKDINSL-TSHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALN 83
Cdd:TIGR03316   1 IKEYIEKLNKLdFKKMYNNDFFLTWEKTDDELKAVFTVADALRALRENNISTKIFDSGLGISLFRDNSTRTRFSFASACN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819    84 LLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQCDI 163
Cdd:TIGR03316  81 LLGLEVQDLDEGKSQIAHGETVRETANMISFMADVIGIRDDMYIGKGNAYMHEVSDSVQEGYKDGVLEQRPTLVNLQCDI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   164 DHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNN 243
Cdd:TIGR03316 161 DHPTQSMADMLHLIHEFGGIENLKGKKVAMTWAYSPSYGKPLSVPQGVIGLFTRFGMDVVLAHPEGYEVMPEVEEVAKKN 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   244 AKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDG 323
Cdd:TIGR03316 241 AAESGGSFTKTNSMAEAFKDADIVYPKSWAPFAAMEKRTNLYGEGDFAGIDALEKELLAQNATHKDWECTEELMKTTKDG 320
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 32469819   324 EALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQER 394
Cdd:TIGR03316 321 KALYLHCLPADITGVSCEEGEVEASVFDRYRVPLYKEASYKPYIIAAMIFLSKVKNPAATLEKLEEKATPR 391
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
17-373 2.83e-105

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 312.76  E-value: 2.83e-105
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  17 SHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGK 96
Cdd:COG0078   1 TNLKGRHFLSLLDLTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKPSTRTRVSFEVGMAQLGGHAIYLDPGD 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  97 SQIAHGETVRETANMISFCADAIGIRddmylGAGNAYMREVGAAlddgykqgvlpQRPALVNLQCDIDHPTQSMADLAWL 176
Cdd:COG0078  81 SQLGRGESIKDTARVLSRYVDGIMIR-----TFGHETLEELAKY-----------AGVPVINGLTDLFHPCQALADLLTI 144
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819 177 REHFGSlenLKGKKIAMTWAyspsygkPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTS 256
Cdd:COG0078 145 REHFGK---LKGLKVAYVGD-------GNNVANSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHD 214
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819 257 MEEAFKDADIVYPKSWAPykvMEQrtellrandheglkalEKQCLAQNAQHKDWHCTEEMMELTRDgEALYMHCLPADIs 336
Cdd:COG0078 215 PAEAVKGADVVYTDVWVS---MGQ----------------EEEAEERIKAFKPYQVNEELMALAKP-DAIFMHCLPAHR- 273
                       330       340       350
                ....*....|....*....|....*....|....*..
gi 32469819 337 gvsckEGEVTEGVFEKYRIATYKEASWKPYIIAAMIL 373
Cdd:COG0078 274 -----GEEVTDEVIDGPQSVVFDEAENRLHAQKALLA 305
PRK04523 PRK04523
N-acetylornithine carbamoyltransferase; Reviewed
22-332 2.13e-45

N-acetylornithine carbamoyltransferase; Reviewed


Pssm-ID: 235304 [Multi-domain]  Cd Length: 335  Bit Score: 159.53  E-value: 2.13e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   22 KDFLLTWEQTPDELKQVLDVAAALKALRaenISTKVFNSGLGIsVFRDNSTRTRFSYASALNLLGLAQQDLDEGKS--QI 99
Cdd:PRK04523   4 KHFLNTQDWSRAELDALLTQAAAFKRNK---LGSALKGKSIAL-VFFNPSLRTRTSFELGAFQLGGHAVVLQPGKDawPI 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  100 AHG----------ETVRETANMISFCADAIGIRddmylgagnAYMREVGAALDdgyKQGVLPQRPA------LVNLQcDI 163
Cdd:PRK04523  80 EFElgavmdgeteEHIREVARVLSRYVDLIGVR---------AFPKFVDWSKD---RQDQVLNSFAkystvpVINME-TI 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  164 DHPTQSMADLAWLREHFGSLenLKGKKIAMTWAYSPsygKPL--SVPQGIIGLMTRFGMDVTLAHP-EGYDLIPDVVEVA 240
Cdd:PRK04523 147 THPCQELAHALALQEHFGTT--LRGKKYVLTWTYHP---KPLntAVANSALLIATRLGMDVTLLCPtPDYILDERYMDWA 221
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  241 KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQ--RTELLRandheglkalekqclaqnAQHKDWHCTEEMME 318
Cdd:PRK04523 222 EQNAAESGGSLTVSHDIDSAYAGADVVYAKSWGALPFFGNwePEKPIR------------------DQYQHFIVDERKMA 283
                        330
                 ....*....|....
gi 32469819  319 LTRDGeaLYMHCLP 332
Cdd:PRK04523 284 LTNNG--VFSHCLP 295
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
22-373 9.44e-42

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 148.65  E-value: 9.44e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819    22 KDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFnSGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIA 100
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLKKGKKKGKEHKKL-KGKTLAlIFEKPSTRTRVSFEVAAYQLGGHPLYLNPNDLQLG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   101 HGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQGVLpQRPA------LVNLQCDIDHPTQSMADLA 174
Cdd:TIGR00658  80 RGESIKDTARVLSRYVDGIMAR---------------------VYKHEDV-EELAkyasvpVINGLTDLFHPCQALADLL 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   175 WLREHFGSLENLKgkkiaMTWAyspsyGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQV 254
Cdd:TIGR00658 138 TIIEHFGKLKGVK-----VVYV-----GDGNNVCNSLMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELT 207
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   255 TSMEEAFKDADIVYPKSWAPykvMEQRTEllranDHEGLKALekqclaqnaqhKDWHCTEEMMELTRDgEALYMHCLPAD 334
Cdd:TIGR00658 208 HDPVEAVKGADVIYTDVWVS---MGEEDK-----KEERLKLF-----------RPYQVNEELMELAKP-EVIFMHCLPAH 267
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 32469819   335 isgvscKEGEVTEGVFEKYRIATYKEASWKPYIIAAMIL 373
Cdd:TIGR00658 268 ------RGEEVTDEVIEGPHSIVFDQAENRLHAQKAVMV 300
PRK00779 PRK00779
ornithine carbamoyltransferase; Provisional
22-351 7.29e-41

ornithine carbamoyltransferase; Provisional


Pssm-ID: 234835 [Multi-domain]  Cd Length: 304  Bit Score: 146.39  E-value: 7.29e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   22 KDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVF-NSGLGIsVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIA 100
Cdd:PRK00779   5 RHFLSLDDLSPEELEELLDLAAELKKKRKAGEPHPPLkGKTLAM-IFEKPSTRTRVSFEVGMAQLGGHAIFLSPRDTQLG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  101 HGETVRETANMISFCADAIGIRDdmylgagnaymrevgaalddgYKQGVL---------PqrpaLVNLQCDIDHPTQSMA 171
Cdd:PRK00779  84 RGEPIEDTARVLSRYVDAIMIRT---------------------FEHETLeelaeystvP----VINGLTDLSHPCQILA 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  172 DLAWLREHFGSLenlKGKKIAmtW-------AYSpsygkplsvpqgiigLM---TRFGMDVTLAHPEGYDLIPDVVEvak 241
Cdd:PRK00779 139 DLLTIYEHRGSL---KGLKVA--WvgdgnnvANS---------------LLlaaALLGFDLRVATPKGYEPDPEIVE--- 195
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPykvMEQRTEllranDHEGLKALekqclaqnaqhKDWHCTEEMMELTR 321
Cdd:PRK00779 196 KIAKETGASIEVTHDPKEAVKGADVVYTDVWVS---MGQEAE-----AEERLKAF-----------APYQVNEELMALAK 256
                        330       340       350
                 ....*....|....*....|....*....|
gi 32469819  322 DgEALYMHCLPADisgvscKEGEVTEGVFE 351
Cdd:PRK00779 257 P-DAIFMHCLPAH------RGEEVTDEVID 279
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
190-374 2.46e-36

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 129.65  E-value: 2.46e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   190 KIAMTWayspsyGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYP 269
Cdd:pfam00185   1 KIAYVG------DGHNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKSGGSIEITDDPAEAVKGADVVYT 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   270 KSWAPykvMEQrtellrandheglkalEKQCLAQNAQHKDWHCTEEMMELTRDgEALYMHCLPADisgvscKEGEVTEGV 349
Cdd:pfam00185  75 DVWQS---MGQ----------------EKEREERLKAFKPYQVNEELMKLAKK-DAIFMHCLPAH------RGEEVTDDV 128
                         170       180
                  ....*....|....*....|....*
gi 32469819   350 FEKYRIATYKEASWKPYIIAAMILS 374
Cdd:pfam00185 129 FDGPRSVVFDQAENRLHAQKALLAL 153
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
23-178 5.50e-32

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 117.91  E-value: 5.50e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819    23 DFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHG 102
Cdd:pfam02729   1 HFLSLEDLSREEIEALLDLAAELKEARKRGKKLPLLKGKTVALLFEEPSTRTRVSFEVAAKRLGGHVIYLSSSDIQLSSG 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 32469819   103 ETVRETANMISFCADAIGIRddmylGAGNAYMREVGAAlddgykqgvlpQRPALVNLQCDIDHPTQSMADLAWLRE 178
Cdd:pfam02729  81 ESLADTARVLSRYVDAIVIR-----HFGHEDLEELAEY-----------ASVPVINAGGDHEHPTQALADLLTIRE 140
PRK02102 PRK02102
ornithine carbamoyltransferase; Validated
17-374 4.55e-31

ornithine carbamoyltransferase; Validated


Pssm-ID: 179366 [Multi-domain]  Cd Length: 331  Bit Score: 120.76  E-value: 4.55e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   17 SHLHEKDFlltweqTPDELKQVLDVAAALKALRAENISTKVFnSGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEG 95
Cdd:PRK02102   9 SFLKLLDF------TPEEIEYLIDLSIELKAAKKAGIEHQYL-EGKNIAlIFEKTSTRTRCAFEVAAIDLGAHVTYLGPN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   96 KSQIAHGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQ----------GVlpqrPALVNLQcDIDH 165
Cdd:PRK02102  82 DSQLGKKESIEDTARVLGRMYDGIEYR---------------------GFKQeiveelakysGV----PVWNGLT-DEWH 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  166 PTQSMADLAWLREHFGSLENLKgkkiamtWAYspsygkplsvpqgiIG---------LM---TRFGMDVTLAHPEGYDLI 233
Cdd:PRK02102 136 PTQMLADFMTMKEHFGPLKGLK-------LAY--------------VGdgrnnmansLMvggAKLGMDVRICAPKELWPE 194
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  234 PDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVY---------PKSWapykvmEQRTELLrandheglkalekqclaqn 304
Cdd:PRK02102 195 EELVALAREIAKETGAKITITEDPEEAVKGADVIYtdvwvsmgeEDEW------EERIKLL------------------- 249
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  305 aqhKDWHCTEEMMELTRDGEALYMHCLPA----------DISGVSCKEG-EVTEGVFEKYRIATYKEASWKPYIIAAMIL 373
Cdd:PRK02102 250 ---KPYQVNMDLMKATGNPDVIFMHCLPAfhdtetkvgkEIAEKYGLKGlEVTDEVFESKYSIVFDEAENRMHTIKAVMV 326

                 .
gi 32469819  374 S 374
Cdd:PRK02102 327 A 327
PLN02342 PLN02342
ornithine carbamoyltransferase
21-387 7.69e-26

ornithine carbamoyltransferase


Pssm-ID: 177976 [Multi-domain]  Cd Length: 348  Bit Score: 106.80  E-value: 7.69e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   21 EKDFLLTWEQTPDELKQVLDVAAALKA-LRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQI 99
Cdd:PLN02342  45 PKHFLHIDDFDKEEILGLLDRAKEVKAlLKSGDRSFQPFKGKSMAMIFTKPSMRTRVSFETGFFLLGGHALYLGPDDIQL 124
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  100 AHGETVRETANMISFCADAIgirddmylgagnayMREVGAALD--DGYKQGVLPqrpaLVNLQCDIDHPTQSMADLAWLR 177
Cdd:PLN02342 125 GKREETRDIARVLSRYNDII--------------MARVFAHQDvlDLAEYSSVP----VINGLTDYNHPCQIMADALTII 186
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  178 EHFGSLENLK------GKKIAMTWAYspsygkplsvpqgiigLMTRFGMDVTLAHPEGYDLIPDVVEvaknNAKASGGSF 251
Cdd:PLN02342 187 EHIGRLEGTKvvyvgdGNNIVHSWLL----------------LAAVLPFHFVCACPKGYEPDAKTVE----KARAAGISK 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  252 RQVTS-MEEAFKDADIVYPKSWAPykvMEQRTEL-LRANDHEGLKALEKqclaqnaqhkdwhcteeMMELTRDGeALYMH 329
Cdd:PLN02342 247 IEITNdPAEAVKGADVVYTDVWAS---MGQKEEAeKRKKAFQGFQVNEA-----------------LMKLAGPQ-AYFMH 305
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 32469819  330 CLPADisgvscKEGEVTEGVFEKYRIATYKEASwkpyiiaamilSRKYAKPGALLEQL 387
Cdd:PLN02342 306 CLPAE------RGVEVTDGVMEAPNSIVFPQAE-----------NRMHAQNAIMLHQL 346
PRK04284 PRK04284
ornithine carbamoyltransferase; Provisional
19-374 3.35e-24

ornithine carbamoyltransferase; Provisional


Pssm-ID: 235269 [Multi-domain]  Cd Length: 332  Bit Score: 101.74  E-value: 3.35e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   19 LHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQ 98
Cdd:PRK04284   4 LRNRSFLTLLDFTPKEIEYLLDLSEDLKRAKYAGIEVQKLKGKNIALIFEKDSTRTRCAFEVAAYDQGAHVTYLGPTGSQ 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   99 IAHGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQ----------GVlpqrpALVNLQCDIDHPTQ 168
Cdd:PRK04284  84 MGKKESTKDTARVLGGMYDGIEYR---------------------GFSQrtvetlaeysGV-----PVWNGLTDEDHPTQ 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  169 SMADLAWLREHF-GSLENLKgkkiaMTW--------AYSPSYGKPLsvpqgiiglmtrFGMDVTLAHPEGYDLIPDVVEV 239
Cdd:PRK04284 138 VLADFLTAKEHLkKPYKDIK-----FTYvgdgrnnvANALMQGAAI------------MGMDFHLVCPKELNPDDELLNK 200
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  240 AKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWA----PYKVMEQRTELLRAndheglkalekqclaqnaqhkdWHCTEE 315
Cdd:PRK04284 201 CKEIAAETGGKITITDDIDEGVKGSDVIYTDVWVsmgePDEVWEERIKLLKP----------------------YQVNKE 258
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  316 MMELTRDGEALYMHCLPA--DISGVSCK---------EGEVTEGVFEKYRIATYKEASWKPYIIAAMILS 374
Cdd:PRK04284 259 MMKKTGNPNAIFEHCLPSfhDLDTKVGKeifekyglkEMEVTDEVFESKASVVFDEAENRMHTIKAVMVA 328
pyrB PRK00856
aspartate carbamoyltransferase catalytic subunit;
25-268 4.64e-21

aspartate carbamoyltransferase catalytic subunit;


Pssm-ID: 234849 [Multi-domain]  Cd Length: 305  Bit Score: 92.44  E-value: 4.64e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   25 LLTWEQ-TPDELKQVLDVAAALKALRAENISTKVFNSGLGI-SVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHG 102
Cdd:PRK00856   8 LLSIEDlSREEIELLLDTAEEFKEVLRREVKKVPLLRGKTVaNLFFEPSTRTRLSFELAAKRLGADVINFSASTSSVSKG 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  103 ETVRETANMIS-FCADAIGIRDDMylgAGNAYM--REVGAAL---DDGYKQgvlpqrpalvnlqcdidHPTQSMADLAWL 176
Cdd:PRK00856  88 ETLADTIRTLSaMGADAIVIRHPQ---SGAARLlaESSDVPVinaGDGSHQ-----------------HPTQALLDLLTI 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  177 REHFGSLENLkgkKIAmtwayspsygkplsvpqgIIG-------------LMTRFGMDVTLAHPEGydLIPDVVEvaknn 243
Cdd:PRK00856 148 REEFGRLEGL---KVA------------------IVGdikhsrvarsniqALTRLGAEVRLIAPPT--LLPEGMP----- 199
                        250       260
                 ....*....|....*....|....*
gi 32469819  244 akasggSFRQVTSMEEAFKDADIVY 268
Cdd:PRK00856 200 ------EYGVHTDLDEVIEDADVVM 218
PRK14805 PRK14805
ornithine carbamoyltransferase; Provisional
22-351 4.11e-20

ornithine carbamoyltransferase; Provisional


Pssm-ID: 237819 [Multi-domain]  Cd Length: 302  Bit Score: 89.75  E-value: 4.11e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   22 KDFLLTWEQTPDELKQVLDVAAALKALRAEnistkvFNSGL-GISV---FRDNSTRTRFSYASALNLLG-----LAQQDL 92
Cdd:PRK14805   2 KHLLSIKELTQQQLLDLLALAKTIKANPAE------YRQALaGKSVvmlFEKPSLRTRVSFDIGINKLGghclyLDQQNG 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   93 DEGKSqiahgETVRETANMISFCADAIGIRDDMYlgagnaymrevgAALDDGYKQGVLPqrpaLVNLQCDIDHPTQSMAD 172
Cdd:PRK14805  76 ALGKR-----ESVADFAANLSCWADAIVARVFSH------------STIEQLAEHGSVP----VINALCDLYHPCQALAD 134
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  173 LAWLREHFGSLENLKgkkiamtWAYspsYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFr 252
Cdd:PRK14805 135 FLTLAEQFGDVSKVK-------LAY---VGDGNNVTHSLMYGAAILGATMTVICPPGHFPDGQIVAEAQELAAKSGGKL- 203
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  253 QVTSMEEAFKDADIVYPKSWAPykvMEQRTELlrandhEGLKalekqclaqnAQHKDWHCTEEMMELTrdGEALYMHCLP 332
Cdd:PRK14805 204 VLTSDIEAIEGHDAIYTDTWIS---MGDDTPL------AEIK----------AKFAPYQVNKALMEKA--GATFVMHCQP 262
                        330
                 ....*....|....*....
gi 32469819  333 ADisgvscKEGEVTEGVFE 351
Cdd:PRK14805 263 AH------RGVEITSEVMD 275
PRK03515 PRK03515
ornithine carbamoyltransferase subunit I; Provisional
17-374 2.48e-19

ornithine carbamoyltransferase subunit I; Provisional


Pssm-ID: 179587 [Multi-domain]  Cd Length: 336  Bit Score: 88.23  E-value: 2.48e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   17 SHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFNsGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEG 95
Cdd:PRK03515   2 NQFYQRHFLRLLDFTPAELNSLLQLAAKLKADKKNGKEEQKLT-GKNIAlIFEKDSTRTRCSFEVAAYDQGARVTYLGPS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   96 KSQIAHGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQGVL---------PQRPALVNLQcdidHP 166
Cdd:PRK03515  81 GSQIGHKESIKDTARVLGRMYDGIQYR---------------------GYGQEIVetlaeyagvPVWNGLTNEF----HP 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  167 TQSMADLAWLREHfgslenLKGKKI-AMTWAY----SPSYGKPLSVPQGIIglmtrfGMDVTLAHPEGYDLIPDVVEVAK 241
Cdd:PRK03515 136 TQLLADLLTMQEH------LPGKAFnEMTLAYagdaRNNMGNSLLEAAALT------GLDLRLVAPKACWPEAALVTECR 203
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  242 NNAKASGGSFRQVTSMEEAFKDADIVYPKSWA----PYKVMEQRTELLRandheglkalekqclaqnaqhkDWHCTEEMM 317
Cdd:PRK03515 204 ALAQKNGGNITLTEDIAEGVKGADFIYTDVWVsmgePKEVWAERIALLR----------------------PYQVNSKMM 261
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 32469819  318 ELTRDGEALYMHCLPA-----DISGVSCKEG-------EVTEGVFEKYRIATYKEASWKPYIIAAMILS 374
Cdd:PRK03515 262 QLTGNPQVKFLHCLPAfhddqTTLGKKMAEEyglhggmEVTDEVFESAHSIVFDQAENRLHTIKAVMVA 330
PRK01713 PRK01713
ornithine carbamoyltransferase; Provisional
18-374 1.15e-17

ornithine carbamoyltransferase; Provisional


Pssm-ID: 167263 [Multi-domain]  Cd Length: 334  Bit Score: 83.11  E-value: 1.15e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   18 HLHEKDFLLTWEQTPDELKQVLDVAAALKalRAENISTKVFN-SGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEG 95
Cdd:PRK01713   4 NLKNRHLLSLVNHTEREIKYLLDLSRDLK--RAKYAGTEQQRlKGKNIAlIFEKTSTRTRCAFEVAAYDQGAQVTYIDPN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   96 KSQIAHGETVRETANMISFCADAIGIRddmylgagnaymrevgaalddGYKQGVLPQRP-----ALVNLQCDIDHPTQSM 170
Cdd:PRK01713  82 SSQIGHKESMKDTARVLGRMYDAIEYR---------------------GFKQSIVNELAeyagvPVFNGLTDEFHPTQML 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  171 ADLAWLREHFGSLENlkgkkiAMTWAYSPSYGKPLSVPQGIIGlmTRFGMDVTLAHPEGydLIPD--VVEVAKNNAKASG 248
Cdd:PRK01713 141 ADVLTMIENCDKPLS------EISYVYIGDARNNMGNSLLLIG--AKLGMDVRICAPKA--LLPEasLVEMCEKFAKESG 210
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  249 GSFRQVTSMEEAFKDADIVYPKSWA----PYKVMEQRTELLRAndheglkalekqclaqnaqhkdWHCTEEMMELTRDGE 324
Cdd:PRK01713 211 ARITVTDDIDKAVKGVDFVHTDVWVsmgePLETWGERIKLLMP----------------------YQVTPELMKRTGNPK 268
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 32469819  325 ALYMHCLPAdISGVSCKEG--------------EVTEGVFEKYRIATYKEASWKPYIIAAMILS 374
Cdd:PRK01713 269 VKFMHCLPA-FHNSETKVGrqiaekypelangiEVTEDVFESPMNIAFEQAENRMHTIKAVMVA 331
PRK12562 PRK12562
ornithine carbamoyltransferase subunit F; Provisional
17-374 2.71e-17

ornithine carbamoyltransferase subunit F; Provisional


Pssm-ID: 105755  Cd Length: 334  Bit Score: 82.03  E-value: 2.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   17 SHLHEKDFLLTWEQTPDELKQVLDVAAALKALRAENISTKVFnSGLGIS-VFRDNSTRTRFSYASALNLLGLAQQDLDEG 95
Cdd:PRK12562   2 SGFYKKHFLKLLDFTPAELNSLLQLAAKLKADKKNGKEVARL-TGKNIAlIFEKDSTRTRCSFEVAAYDQGARVTYLGPS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   96 KSQIAHGETVRETANMISFCADAIgirddMYLGAGnaymREVGAALDDgyKQGVlPQRPALVNLQcdidHPTQSMADLAW 175
Cdd:PRK12562  81 GSQIGHKESIKDTARVLGRMYDGI-----QYRGHG----QEVVETLAE--YAGV-PVWNGLTNEF----HPTQLLADLLT 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  176 LREHfgslenLKGKKI-AMTWAYSPSYGKPLSvpQGIIGLMTRFGMDVTLAHPEGydLIPDVVEVAKNNAKA--SGGSFR 252
Cdd:PRK12562 145 MQEH------LPGKAFnEMTLVYAGDARNNMG--NSMLEAAALTGLDLRLVAPQA--CWPEASLVAECSALAqkHGGKIT 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  253 QVTSMEEAFKDADIVYPKSWA----PYKVMEQRTELLRandheglkalekqclaqnaqhkDWHCTEEMMELTRDGEALYM 328
Cdd:PRK12562 215 LTEDIAAGVKGADFIYTDVWVsmgePKEKWAERIALLR----------------------GYQVNSKMMALTGNPQVKFL 272
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 32469819  329 HCLPA---DISGVSCKEG---------EVTEGVFEKYRIATYKEASWKPYIIAAMILS 374
Cdd:PRK12562 273 HCLPAfhdDQTTLGKKMAkefglhggmEVTDEVFESPASIVFDQAENRMHTIKAVMVA 330
PRK11891 PRK11891
aspartate carbamoyltransferase; Provisional
25-268 4.59e-10

aspartate carbamoyltransferase; Provisional


Pssm-ID: 183362 [Multi-domain]  Cd Length: 429  Bit Score: 61.03  E-value: 4.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   25 LLTWEQ-TPDELKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQD-LDEGKSQIAHG 102
Cdd:PRK11891  90 LLSVDQfSRDSVEALFRVADVMQPIARRQKISRVLEGAVLGNLFFEASTRTRVSFGAAFCRLGGSVCDtTGFTFSSMAKG 169
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  103 ETVRETANMISFCADAIGIRDDMyLGAGNAYMREVGAALDDGykqGVLPQrpalvnlqcdiDHPTQSMADLAWLREHFGS 182
Cdd:PRK11891 170 ESIYDTSRVMSGYVDALVIRHPE-QGSVAEFARATNLPVING---GDGPG-----------EHPSQALLDLYTIQREFSR 234
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  183 LENL-KGKKIAMTWAYspSYGKPLsvpQGIIGLMTRF-GMDVTLAHPEGYDLIPDVVEVAKNNakasGGSFRQVTSMEEA 260
Cdd:PRK11891 235 LGKIvDGAHIALVGDL--KYGRTV---HSLVKLLALYrGLKFTLVSPPTLEMPAYIVEQISRN----GHVIEQTDDLAAG 305

                 ....*...
gi 32469819  261 FKDADIVY 268
Cdd:PRK11891 306 LRGADVVY 313
PRK08192 PRK08192
aspartate carbamoyltransferase; Provisional
33-268 1.04e-07

aspartate carbamoyltransferase; Provisional


Pssm-ID: 169269 [Multi-domain]  Cd Length: 338  Bit Score: 53.19  E-value: 1.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   33 DELKQVLDVAAALK--ALRAEniSTKVFNSGLGISVFRDNSTRTRFSYASALNLL-GLAQQDLDEGKSQIAHGETVRETA 109
Cdd:PRK08192  17 DAIQRIFNVADRMEpyALREK--RTRVLEGAILGNLFFEPSTRTRVSFGCAFNLLgGHVRETTGMASSSLSKGESLYDTA 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  110 NMISFCADAIGIRD-DMYLGAGNAYMREV----GAaldDGYKQgvlpqrpalvnlqcdidHPTQSMADLAWLR---EHFG 181
Cdd:PRK08192  95 RVLSTYSDVIAMRHpDAGSVKEFAEGSRVpvinGG---DGSNE-----------------HPTQALLDLFTIQkelAHAG 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  182 slENLKGKKIAMTWAYspSYGKPLSVPQGIIGLMTRfgMDVTLAHPEGYDLiPDVVEVAKNNAkasGGSFRQVTSMEEAF 261
Cdd:PRK08192 155 --RGIDGMHIAMVGDL--KFGRTVHSLSRLLCMYKN--VSFTLVSPKELAM-PDYVISDIENA---GHKITITDQLEGNL 224

                 ....*..
gi 32469819  262 KDADIVY 268
Cdd:PRK08192 225 DKADILY 231
PLN02527 PLN02527
aspartate carbamoyltransferase
35-268 5.53e-06

aspartate carbamoyltransferase


Pssm-ID: 178142 [Multi-domain]  Cd Length: 306  Bit Score: 47.82  E-value: 5.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   35 LKQVLDVAAALKALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGK--SQIAHGETVRETANMI 112
Cdd:PLN02527  14 LELLFEVAREMEKVERGSPGSQMLKGYLMATLFYEPSTRTRLSFESAMKRLGGEVLTTENAGefSSAAKGETLEDTIRTV 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  113 SFCADAIGIRddmYLGAGNAymREVGAALD-------DGYKQgvlpqrpalvnlqcdidHPTQSMADLAWLREHFGSLEN 185
Cdd:PLN02527  94 EGYSDIIVLR---HFESGAA--RRAAATAEipvinagDGPGQ-----------------HPTQALLDVYTIQREIGRLDG 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  186 LkgkKIAMTWAYspSYGKPLsvpQGIIGLMTRFGmDVTLahpegYDLIPDVVEVA---KNNAKASGGSFRQVTSMEEAFK 262
Cdd:PLN02527 152 I---KVGLVGDL--ANGRTV---RSLAYLLAKYE-DVKI-----YFVAPDVVKMKddiKDYLTSKGVEWEESSDLMEVAS 217

                 ....*.
gi 32469819  263 DADIVY 268
Cdd:PLN02527 218 KCDVLY 223
PRK14804 PRK14804
ornithine carbamoyltransferase; Provisional
25-285 7.67e-06

ornithine carbamoyltransferase; Provisional


Pssm-ID: 173265 [Multi-domain]  Cd Length: 311  Bit Score: 47.33  E-value: 7.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819   25 LLTWEQTPD-ELKQVLDVAAALKALRAeNISTKVFNSGLGIsVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE 103
Cdd:PRK14804   9 LISWEDWSDsEILDLLDFAVHVKKNRV-NYAGHMSGRSLAM-LFQKTSTRTRVSFEVAMTEMGGHGIYLDWMASNFQLSD 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  104 T---VRETANMISFCADAIGIRDDMYLgagnaymrevgaalddgYKQGvlPQRPaLVNLQCDIDHPTQSMADLAWLrehf 180
Cdd:PRK14804  87 IdleARYLSRNVSVIMARLKKHEDLLV-----------------MKNG--SQVP-VINGCDNMFHPCQSLADIMTI---- 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32469819  181 gSLE--NLKGKKIAMTWayspsYGKPLSVPQGIIGLMTRFGMDVTLAHP--EGYDLIPDVVEVAKnnakaSGGSFRQVTS 256
Cdd:PRK14804 143 -ALDspEIPLNQKQLTY-----IGVHNNVVNSLIGITAALGIHLTLVTPiaAKENIHAQTVERAK-----KKGTLSWEMN 211
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 32469819  257 MEEAFKDADIVYPKSWAPYKVM---------EQRTELL 285
Cdd:PRK14804 212 LHKAVSHADYVYTDTWLDMEFFndpsyadkkKQRMELM 249
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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