|
Name |
Accession |
Description |
Interval |
E-value |
| DSRM_SON-like |
cd19870 |
double-stranded RNA binding motif of protein SON and similar proteins; Protein SON (also known ... |
2387-2437 |
3.85e-28 |
|
double-stranded RNA binding motif of protein SON and similar proteins; Protein SON (also known as Bax antagonist selected in saccharomyces 1 (BASS1), negative regulatory element-binding protein (NRE-binding protein), or protein DBP-5, or SON3) is an RNA-binding protein which acts as an mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. It specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Members of this group contain a double-stranded RNA binding motif (DSRM) at the C-terminus. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380699 Cd Length: 75 Bit Score: 109.29 E-value: 3.85e-28
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 338817942 2387 GKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPYQPNC 2437
Cdd:cd19870 1 GKHPVSALMELCNKRKWGPPEFRLVEESGPPHRKHFLFKVVVNGVEYQPSV 51
|
|
| G-patch |
pfam01585 |
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ... |
2323-2367 |
6.00e-17 |
|
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.
Pssm-ID: 396249 [Multi-domain] Cd Length: 45 Bit Score: 76.39 E-value: 6.00e-17
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 338817942 2323 TGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAV 2367
Cdd:pfam01585 1 TSNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEAKIKKDRRGLGAE 45
|
|
| G_patch |
smart00443 |
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ... |
2321-2367 |
2.35e-15 |
|
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.
Pssm-ID: 197727 [Multi-domain] Cd Length: 47 Bit Score: 71.81 E-value: 2.35e-15
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 338817942 2321 PVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAV 2367
Cdd:smart00443 1 ISTSNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLGAV 47
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1323-1501 |
1.65e-10 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 66.99 E-value: 1.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1323 PAVTISQPAENSLELPSMTVPAPstmTTTESPVVAVTEippVAVPEPPIMAVPELPTMAVVKTPAVAVPEPLVAAPEPPT 1402
Cdd:PRK10811 846 PVVRPQDVQVEEQREAEEVQVQP---VVAEVPVAAAVE---PVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEV 919
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1403 MATPelcslsvseppvaVSELPALADPEHAITAVSGVSSLEPSVPILEPAVSVLQPV----MIVSEPSVPVQEPTVAVSE 1478
Cdd:PRK10811 920 IAAP-------------VTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAetaeVVVAEPEVVAQPAAPVVAE 986
|
170 180
....*....|....*....|...
gi 338817942 1479 PAVIVSEHtqiTSPEMAVESSPV 1501
Cdd:PRK10811 987 VAAEVETV---TAVEPEVAPAQV 1006
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
173-456 |
1.12e-08 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 60.55 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 173 GLSEASETALVLEPPVVSMEVQESHVLETLKPATKAA---ELSVVSTSVISEQSEQPMPGmLEPSMTKILDSFTaaPVPM 249
Cdd:NF033839 146 DSSSSSSSGSSTKPETPQPENPEHQKPTTPAPDTKPSpqpEGKKPSVPDINQEKEKAKLA-VATYMSKILDDIQ--KHHL 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 250 STAALKSPEPVVTMSVEYQKSVLKSLETMPPETSKTTLVELPIAKV--VEPSETLTIVSETPTE-VHPEPS---PSTMDF 323
Cdd:NF033839 223 QKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMdaVVTKFKKGLTQDTPKEpGNKKPSapkPGMQPS 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 324 PESSTTDVQRLPEQPVEAPSEIADSSMTRPQESLELPKTTA---VELQESTVASALELPGPPATSILELQGPPVTPVPEL 400
Cdd:NF033839 303 PQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVkpqLETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPET 382
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 338817942 401 PGPSATPVPELSGPLSTPVPELPGPPATVVPELPGPSVTPVPQLSQE--LPGPPAPSM 456
Cdd:NF033839 383 PKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPevKPQPEKPKP 440
|
|
| DSRM |
smart00358 |
Double-stranded RNA binding motif; |
2390-2433 |
2.43e-07 |
|
Double-stranded RNA binding motif;
Pssm-ID: 214634 [Multi-domain] Cd Length: 67 Bit Score: 49.95 E-value: 2.43e-07
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 338817942 2390 PVSALMEICNKRRWqPPEFLLVHDSGPDHRKHFLFRVLRNGSPY 2433
Cdd:smart00358 1 PKSLLQELAQKRKL-PPEYELVKEEGPDHAPRFTVTVKVGGKRT 43
|
|
| DND1_DSRM |
pfam14709 |
double strand RNA binding domain from DEAD END PROTEIN 1; A C-terminal domain in human dead ... |
2390-2441 |
3.27e-07 |
|
double strand RNA binding domain from DEAD END PROTEIN 1; A C-terminal domain in human dead end protein 1 (DND1_HUMAN) homologous to double strand RNA binding domains (PF00035, PF00333)
Pssm-ID: 405408 Cd Length: 80 Bit Score: 50.03 E-value: 3.27e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 338817942 2390 PVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNG--SPYQPNCMFFL 2441
Cdd:pfam14709 3 AVSHLEELCQKNKWGSPVYELHSTAGPDGKQLFTYKVVIPGieTPFPGVIWIFM 56
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
233-482 |
5.25e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.71 E-value: 5.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 233 PSMTKILDSFTAAPVPMSTAALKSPEPVVTMSVEYQKSVlksleTMPPETSKTTLVELPIAKVVEPSETLTIVSETPTEV 312
Cdd:PHA03247 2760 PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESL-----PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSA 2834
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 313 HPEPSPSTMDFPESSTT---------DVQRLP--EQPV---EAPSEIADSSMTRPQeslelpkttaveLQESTVASALEL 378
Cdd:PHA03247 2835 QPTAPPPPPGPPPPSLPlggsvapggDVRRRPpsRSPAakpAAPARPPVRRLARPA------------VSRSTESFALPP 2902
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 379 PGPPATSILELQGPPVTPVPELPGPSATPVPElsgplSTPVPELPGPPATVVPELPGPS-VTPVPQLSQELPG------- 450
Cdd:PHA03247 2903 DQPERPPQPQAPPPPQPQPQPPPPPQPQPPPP-----PPPRPQPPLAPTTDPAGAGEPSgAVPQPWLGALVPGrvavprf 2977
|
250 260 270
....*....|....*....|....*....|....*
gi 338817942 451 ---PPAPSMgleppqEVPEPPVMAQELSGVPAVSA 482
Cdd:PHA03247 2978 rvpQPAPSR------EAPASSTPPLTGHSLSRVSS 3006
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
209-454 |
6.22e-06 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 51.69 E-value: 6.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 209 AELSVVSTSVISEQSEQPMPGMLEPSMTKILDSFTA-APVPMSTAALKSPEPVVTMSVEYQKSVLKSlETMPPETSKTTL 287
Cdd:NF033839 246 SEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQdTPKEPGNKKPSAPKPGMQPSPQPEKKEVKP-EPETPKPEVKPQ 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 288 VELPIAKVVEPSETltivseTPTEVHPE---PSPSTMDFPESSTTDVQRLPEQPVEAPSEIADSSMTRPQESLELPK--- 361
Cdd:NF033839 325 LEKPKPEVKPQPEK------PKPEVKPQletPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKpev 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 362 TTAVELQESTVASALELPGPPATSILELQGPPVTPVPELPGPSATPVPELSGPLSTPVPELPGPPATVVPELPGPSVTPV 441
Cdd:NF033839 399 KPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQ 478
|
250
....*....|...
gi 338817942 442 PQLSQELPGPPAP 454
Cdd:NF033839 479 PEKPKPDNSKPQA 491
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
333-641 |
2.26e-05 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 50.06 E-value: 2.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 333 RLPEQPVEAPSEIADSSMTRPQESLELPKTTAVE-LQESTVASALELPGPPATSILElQGP---------------PVTP 396
Cdd:PHA03379 396 KLTERAREALEKASEPTYGTPRPPVEKPRPEVPQsLETATSHGSAQVPEPPPVHDLE-PGPlhdqhsmapcpvaqlPPGP 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 397 VP------ELPG------PSATPVPELSGPLSTP----VPELPG-PPATVVPE-LPGPSVtPVPQLSQELPGPPAPSMGL 458
Cdd:PHA03379 475 LQdlepgdQLPGvvqdgrPACAPVPAPAGPIVRPweasLSQVPGvAFAPVMPQpMPVEPV-PVPTVALERPVCPAPPLIA 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 459 EPPQEVPEPPVMAQELSGVPAVS-------AAIELTGQPA----------VTVAMELTEQPVTTTE--FEQPVAMTTVEH 519
Cdd:PHA03379 554 MQGPGETSGIVRVRERWRPAPWTpnpprspSQMSVRDRLArlraeaqpyqASVEVQPPQLTQVSPQqpMEYPLEPEQQMF 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 520 PGHP-----EVTTATGL--LGQPEAAMVLELP---GQPVATTALELSGQPSVTG-------VPELSGLPSATRALELSGQ 582
Cdd:PHA03379 634 PGSPfsqvaDVMRAGGVpaMQPQYFDLPLQQPisqGAPLAPLRASMGPVPPVPAtqpqyfdIPLTEPINQGASAAHFLPQ 713
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 338817942 583 SVATGALeLPGQLMATGALEFSGQSGAAGALELLGQPLATGVLElpGQPGAPELPGQPV 641
Cdd:PHA03379 714 QPMEGPL-VPERWMFQGATLSQSVRPGVAQSQYFDLPLTQPINH--GAPAAHFLHQPPM 769
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1272-1511 |
7.10e-05 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 48.37 E-value: 7.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1272 PMTYMVSETTMSVEPAVLTSEASVISETSETYDSMRPSGHAISEVTMSLlePAVT-----ISQPAEN--SLELPSMTVPA 1344
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKVIFSKAPESTTTSPTLNTTGFAAPNTTTGL--PSSThvptnLTAPASTgpTVSTADVTSPT 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1345 PSTMTTTESPVVAvteiPPVAVPEPPIMAVPEL--PTMAVVK-TPAVAVPEPLVAAPEP----PTMATPELCSLSVSEPP 1417
Cdd:pfam05109 478 PAGTTSGASPVTP----SPSPRDNGTESKAPDMtsPTSAVTTpTPNATSPTPAVTTPTPnatsPTLGKTSPTSAVTTPTP 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1418 VAVSELPALADPEhaitavsgvsslePSVPIlePAVSVLQPVMIVSEPSVPVQEPTVAVSEPAVIVSEHT-QITSPEMAV 1496
Cdd:pfam05109 554 NATSPTPAVTTPT-------------PNATI--PTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTlGGTSSTPVV 618
|
250
....*....|....*
gi 338817942 1497 ESSPVIVDSSVMSSQ 1511
Cdd:pfam05109 619 TSPPKNATSAVTTGQ 633
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1191-1393 |
1.82e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 46.96 E-value: 1.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1191 TEVTLSTGESLSQPEPPVSQSEISEPMAVPAnysmsesETSMLASEAVMTVPEPAREPEssVTSAPVESAVVAEHEMVPE 1270
Cdd:PRK10811 848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAA-------VEPVVSAPVVEAVAEVVEEPV--VVAEPQPEEVVVVETTHPE 918
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1271 rpmtymVSETTMSVEPAVLT-SEASVISETSETydsmrpsGHAISEVtmsllEPAVTISQPAENSLElpsMTVPAPSTMT 1349
Cdd:PRK10811 919 ------VIAAPVTEQPQVITeSDVAVAQEVAEH-------AEPVVEP-----QDETADIEEAAETAE---VVVAEPEVVA 977
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 338817942 1350 TTESPVVAVTEIPPVAVPEPPIMAVPELPTMAVV----------KTPAVA-VPEP 1393
Cdd:PRK10811 978 QPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVehnhatapmtRAPAPEyVPEA 1032
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
82-574 |
3.26e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.30 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 82 DLKEASRKSRCVSV--QTDPTDEVPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESE--SKLKSHHDGNLESDSFLKFD 157
Cdd:pfam03154 38 DLRSSGRNSPSAAStsSNDSKAESMKKSSKKIKEEAPSPLKSAKRQREKGASDTEEPEraTAKKSKTQEISRPNSPSEGE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 158 SEPSAAALEHPVRAFGLSEASETALVLEPPVVSMEVQESHvletlkpATKAAELSVVSTSVISEQSEQPMPGMLEPSMTK 237
Cdd:pfam03154 118 GESSDGRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESD-------SDSSAQQQILQTQPPVLQAQSGAASPPSPPPPG 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 238 ILDSFTAAPVPMSTAALKSPEPVVTMSVEYQKSvlksleTMPPETSKTTLVELPIAKVVEPSETLTIV------SETPTE 311
Cdd:pfam03154 191 TTQAATAGPTPSAPSVPPQGSPATSQPPNQTQS------TAAPHTLIQQTPTLHPQRLPSPHPPLQPMtqppppSQVSPQ 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 312 VHPEPSPSTMDFP-----ESSTTDVQR-LPEQPVEAPSEIADS------SMTRPQESLELPKTTAVELQESTVASALELP 379
Cdd:pfam03154 265 PLPQPSLHGQMPPmphslQTGPSHMQHpVPPQPFPLTPQSSQSqvppgpSPAAPGQSQQRIHTPPSQSQLQSQQPPREQP 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 380 GPPA-TSILELQGPPVTPVPELPGPSATPVP-ELSGPLSTPVP-ELPGPPA----TVVPELPGPSVTPVP-QL---SQEL 448
Cdd:pfam03154 345 LPPApLSMPHIKPPPTTPIPQLPNPQSHKHPpHLSGPSPFQMNsNLPPPPAlkplSSLSTHHPPSAHPPPlQLmpqSQQL 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 449 PGPPAPSMGLEPPQEVPEPPVMAQELSGVPAVSAAIELTGQPAVTVAMELTEQPvTTTEFEQPVAMTTVEHPGHPEVTTA 528
Cdd:pfam03154 425 PPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPP-SGPPTSTSSAMPGIQPPSSASVSSS 503
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 338817942 529 TGLLGQPEAAmvleLPGQPVATTALELSGQPSVTGVPELSGLPSAT 574
Cdd:pfam03154 504 GPVPAAVSCP----LPPVQIKEEALDEAEEPESPPPPPRSPSPEPT 545
|
|
| Rnc |
COG0571 |
dsRNA-specific ribonuclease [Transcription]; |
2380-2433 |
3.11e-03 |
|
dsRNA-specific ribonuclease [Transcription];
Pssm-ID: 440336 [Multi-domain] Cd Length: 229 Bit Score: 41.62 E-value: 3.11e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 338817942 2380 AAMKDLSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPY 2433
Cdd:COG0571 149 EIAPGGAGKDYKTALQEWLQARGLPLPEYEVVEEEGPDHAKTFTVEVLVGGKVL 202
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DSRM_SON-like |
cd19870 |
double-stranded RNA binding motif of protein SON and similar proteins; Protein SON (also known ... |
2387-2437 |
3.85e-28 |
|
double-stranded RNA binding motif of protein SON and similar proteins; Protein SON (also known as Bax antagonist selected in saccharomyces 1 (BASS1), negative regulatory element-binding protein (NRE-binding protein), or protein DBP-5, or SON3) is an RNA-binding protein which acts as an mRNA splicing cofactor by promoting efficient splicing of transcripts that possess weak splice sites. It specifically promotes splicing of many cell-cycle and DNA-repair transcripts that possess weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG. Members of this group contain a double-stranded RNA binding motif (DSRM) at the C-terminus. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380699 Cd Length: 75 Bit Score: 109.29 E-value: 3.85e-28
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 338817942 2387 GKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPYQPNC 2437
Cdd:cd19870 1 GKHPVSALMELCNKRKWGPPEFRLVEESGPPHRKHFLFKVVVNGVEYQPSV 51
|
|
| G-patch |
pfam01585 |
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ... |
2323-2367 |
6.00e-17 |
|
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.
Pssm-ID: 396249 [Multi-domain] Cd Length: 45 Bit Score: 76.39 E-value: 6.00e-17
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 338817942 2323 TGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAV 2367
Cdd:pfam01585 1 TSNIGFKLLQKMGWKEGQGLGKNEQGIAEPIEAKIKKDRRGLGAE 45
|
|
| G_patch |
smart00443 |
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ... |
2321-2367 |
2.35e-15 |
|
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.
Pssm-ID: 197727 [Multi-domain] Cd Length: 47 Bit Score: 71.81 E-value: 2.35e-15
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 338817942 2321 PVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGLVAV 2367
Cdd:smart00443 1 ISTSNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLGAV 47
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1323-1501 |
1.65e-10 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 66.99 E-value: 1.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1323 PAVTISQPAENSLELPSMTVPAPstmTTTESPVVAVTEippVAVPEPPIMAVPELPTMAVVKTPAVAVPEPLVAAPEPPT 1402
Cdd:PRK10811 846 PVVRPQDVQVEEQREAEEVQVQP---VVAEVPVAAAVE---PVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEV 919
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1403 MATPelcslsvseppvaVSELPALADPEHAITAVSGVSSLEPSVPILEPAVSVLQPV----MIVSEPSVPVQEPTVAVSE 1478
Cdd:PRK10811 920 IAAP-------------VTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAetaeVVVAEPEVVAQPAAPVVAE 986
|
170 180
....*....|....*....|...
gi 338817942 1479 PAVIVSEHtqiTSPEMAVESSPV 1501
Cdd:PRK10811 987 VAAEVETV---TAVEPEVAPAQV 1006
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
173-456 |
1.12e-08 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 60.55 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 173 GLSEASETALVLEPPVVSMEVQESHVLETLKPATKAA---ELSVVSTSVISEQSEQPMPGmLEPSMTKILDSFTaaPVPM 249
Cdd:NF033839 146 DSSSSSSSGSSTKPETPQPENPEHQKPTTPAPDTKPSpqpEGKKPSVPDINQEKEKAKLA-VATYMSKILDDIQ--KHHL 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 250 STAALKSPEPVVTMSVEYQKSVLKSLETMPPETSKTTLVELPIAKV--VEPSETLTIVSETPTE-VHPEPS---PSTMDF 323
Cdd:NF033839 223 QKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMdaVVTKFKKGLTQDTPKEpGNKKPSapkPGMQPS 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 324 PESSTTDVQRLPEQPVEAPSEIADSSMTRPQESLELPKTTA---VELQESTVASALELPGPPATSILELQGPPVTPVPEL 400
Cdd:NF033839 303 PQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVkpqLETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPET 382
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 338817942 401 PGPSATPVPELSGPLSTPVPELPGPPATVVPELPGPSVTPVPQLSQE--LPGPPAPSM 456
Cdd:NF033839 383 PKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPevKPQPEKPKP 440
|
|
| DSRM |
smart00358 |
Double-stranded RNA binding motif; |
2390-2433 |
2.43e-07 |
|
Double-stranded RNA binding motif;
Pssm-ID: 214634 [Multi-domain] Cd Length: 67 Bit Score: 49.95 E-value: 2.43e-07
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 338817942 2390 PVSALMEICNKRRWqPPEFLLVHDSGPDHRKHFLFRVLRNGSPY 2433
Cdd:smart00358 1 PKSLLQELAQKRKL-PPEYELVKEEGPDHAPRFTVTVKVGGKRT 43
|
|
| DND1_DSRM |
pfam14709 |
double strand RNA binding domain from DEAD END PROTEIN 1; A C-terminal domain in human dead ... |
2390-2441 |
3.27e-07 |
|
double strand RNA binding domain from DEAD END PROTEIN 1; A C-terminal domain in human dead end protein 1 (DND1_HUMAN) homologous to double strand RNA binding domains (PF00035, PF00333)
Pssm-ID: 405408 Cd Length: 80 Bit Score: 50.03 E-value: 3.27e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 338817942 2390 PVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNG--SPYQPNCMFFL 2441
Cdd:pfam14709 3 AVSHLEELCQKNKWGSPVYELHSTAGPDGKQLFTYKVVIPGieTPFPGVIWIFM 56
|
|
| DSRM_RNAse_III_family |
cd10845 |
double-stranded RNA binding motif of ribonuclease III (RNase III) and similar proteins; RNase ... |
2388-2433 |
4.07e-07 |
|
double-stranded RNA binding motif of ribonuclease III (RNase III) and similar proteins; RNase III (EC 3.1.26.3; also known as ribonuclease 3) digests double-stranded RNA formed within single-strand substrates, but not RNA-DNA hybrids. It is involved in the processing of rRNA precursors, viral transcripts, some mRNAs, and at least 1 tRNA (metY, a minor form of tRNA-init-Met). It cleaves the 30S primary rRNA transcript to yield the immediate precursors to the 16S and 23S rRNAs. The cleavage can occur in assembled 30S, 50S, and even 70S subunits and is influenced by the presence of ribosomal proteins. The RNase III family also includes the mitochondrion-specific ribosomal protein mL44 subfamily, which is composed of mitochondrial 54S ribosomal protein L3 (MRPL3) and mitochondrial 39S ribosomal protein L44 (MRPL44). Members of this family contain an RNase III domain and a C-terminal double-stranded RNA binding motif (DSRM). DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380682 [Multi-domain] Cd Length: 69 Bit Score: 49.03 E-value: 4.07e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 338817942 2388 KHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPY 2433
Cdd:cd10845 1 KDYKTALQEYLQKRGLPLPEYELVEEEGPDHNKTFTVEVKVNGKVI 46
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
233-482 |
5.25e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.71 E-value: 5.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 233 PSMTKILDSFTAAPVPMSTAALKSPEPVVTMSVEYQKSVlksleTMPPETSKTTLVELPIAKVVEPSETLTIVSETPTEV 312
Cdd:PHA03247 2760 PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESL-----PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSA 2834
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 313 HPEPSPSTMDFPESSTT---------DVQRLP--EQPV---EAPSEIADSSMTRPQeslelpkttaveLQESTVASALEL 378
Cdd:PHA03247 2835 QPTAPPPPPGPPPPSLPlggsvapggDVRRRPpsRSPAakpAAPARPPVRRLARPA------------VSRSTESFALPP 2902
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 379 PGPPATSILELQGPPVTPVPELPGPSATPVPElsgplSTPVPELPGPPATVVPELPGPS-VTPVPQLSQELPG------- 450
Cdd:PHA03247 2903 DQPERPPQPQAPPPPQPQPQPPPPPQPQPPPP-----PPPRPQPPLAPTTDPAGAGEPSgAVPQPWLGALVPGrvavprf 2977
|
250 260 270
....*....|....*....|....*....|....*
gi 338817942 451 ---PPAPSMgleppqEVPEPPVMAQELSGVPAVSA 482
Cdd:PHA03247 2978 rvpQPAPSR------EAPASSTPPLTGHSLSRVSS 3006
|
|
| DSRM_PRKRA-like_rpt2 |
cd19863 |
second double-stranded RNA binding motif of PRKRA, TARBP2 and similar proteins; The family ... |
2389-2422 |
2.63e-06 |
|
second double-stranded RNA binding motif of PRKRA, TARBP2 and similar proteins; The family includes protein activator of the interferon-induced protein kinase (PRKRA) and the RISC-loading complex subunit TARBP2. PRKRA (also known as interferon-inducible double-stranded RNA-dependent protein kinase activator A, PKR-associated protein X (RAX), PKR-associating protein X, protein kinase, interferon-inducible double-stranded RNA-dependent activator, PACT, or HSD14) is a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling. TARBP2 (also called TAR RNA-binding protein 2, or trans-activation-responsive RNA-binding protein (TRBP)) participates in the formation of the RNA-induced silencing complex (RISC). It is part of the RISC-loading complex (RLC), together with dicer1 and eif2c2/ago2, and is required to process precursor miRNAs. The family also includes Drosophila melanogaster Loquacious and similar proteins. Loquacious (Loqs) is a double-stranded RNA-binding domain (dsRBD) protein, a homolog of human TAR RNA binding protein (TRBP) that is a protein first identified as binding the HIV trans-activator RNA (TAR). Loqs interacts with Dicer1 (dmDcr1) to facilitate miRNA processing. PRKRA family proteins contain three double-stranded RNA binding motifs (DSRMs). This model describes the second motif. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380692 Cd Length: 67 Bit Score: 46.99 E-value: 2.63e-06
10 20 30
....*....|....*....|....*....|....
gi 338817942 2389 HPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHF 2422
Cdd:cd19863 1 NPVGILQELCVQRRWRLPEYEVEQESGPPHEKEF 34
|
|
| G-patch_2 |
pfam12656 |
G-patch domain; Yeast Spp2, a G-patch protein and spliceosome component, interacts with the ... |
2319-2364 |
2.95e-06 |
|
G-patch domain; Yeast Spp2, a G-patch protein and spliceosome component, interacts with the ATP-dependent DExH-box splicing factor Prp2. As this interaction involves the G-patch sequence in Spp2 and is required for the recruitment of Prp2 to the spliceosome before the first catalytic step of splicing, it is proposed that Spp2 might be an accessory factor that confers spliceosome specificity on Prp2.
Pssm-ID: 432700 [Multi-domain] Cd Length: 61 Bit Score: 46.50 E-value: 2.95e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 338817942 2319 AAPVtGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTDRKGL 2364
Cdd:pfam12656 11 KVPV-EEFGAAMLRGMGWKPGQGIGKNKKGDVKPKEYKRRPGGLGL 55
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1299-1502 |
5.15e-06 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 52.39 E-value: 5.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1299 TSETYDSMRP--SGHAISEvTMSLLEPAVTISQPAENSLELPSMTVPAPSTMTTTESPVVAVTEIPPVAVPEPPIMAVPE 1376
Cdd:PRK10263 300 TQPEYDEYDPllNGAPITE-PVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPE 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1377 -LPTMAVVKTPAVAVPEPLvAAPEPPTMATPELCSLSVSEPPVAVSELPALADPEHAITAVSGVSSLEPSVPilEPAVSV 1455
Cdd:PRK10263 379 gYPQQSQYAQPAVQYNEPL-QQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQA--EEQQST 455
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 338817942 1456 LQPvmivsepsVPVQEPTVAVSEPAVIVSEHT--QITSPEMAVESSPVI 1502
Cdd:PRK10263 456 FAP--------QSTYQTEQTYQQPAAQEPLYQqpQPVEQQPVVEPEPVV 496
|
|
| DSRM_DCL_plant |
cd19869 |
double-stranded RNA binding motif of plant Dicer-like proteins; The family includes plant ... |
2396-2426 |
6.11e-06 |
|
double-stranded RNA binding motif of plant Dicer-like proteins; The family includes plant Dicer-like (DCL) proteins and other ribonuclease (RNase) III-like (RTL) proteins. DCLs are endoribonucleases involved in RNA-mediated post-transcriptional gene silencing (PTGS). They function in the microRNA (miRNA) biogenesis pathway by cleaving primary miRNAs (pri-miRNAs) and precursor miRNAs (pre-miRNAs). Family members contain a double-stranded RNA binding motif (DSRM) at the C-terminus. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380698 Cd Length: 70 Bit Score: 45.82 E-value: 6.11e-06
10 20 30
....*....|....*....|....*....|.
gi 338817942 2396 EICNKRRWQPPEFLLVHDSGPDHRKHFLFRV 2426
Cdd:cd19869 2 EICLKRRWPMPVYRCVEEEGPAHAKRFTYMV 32
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
209-454 |
6.22e-06 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 51.69 E-value: 6.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 209 AELSVVSTSVISEQSEQPMPGMLEPSMTKILDSFTA-APVPMSTAALKSPEPVVTMSVEYQKSVLKSlETMPPETSKTTL 287
Cdd:NF033839 246 SEIDNVNTKVEIENTVHKIFADMDAVVTKFKKGLTQdTPKEPGNKKPSAPKPGMQPSPQPEKKEVKP-EPETPKPEVKPQ 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 288 VELPIAKVVEPSETltivseTPTEVHPE---PSPSTMDFPESSTTDVQRLPEQPVEAPSEIADSSMTRPQESLELPK--- 361
Cdd:NF033839 325 LEKPKPEVKPQPEK------PKPEVKPQletPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKpev 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 362 TTAVELQESTVASALELPGPPATSILELQGPPVTPVPELPGPSATPVPELSGPLSTPVPELPGPPATVVPELPGPSVTPV 441
Cdd:NF033839 399 KPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQ 478
|
250
....*....|...
gi 338817942 442 PQLSQELPGPPAP 454
Cdd:NF033839 479 PEKPKPDNSKPQA 491
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
1318-1495 |
1.57e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 50.25 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1318 MSLL-----EPAVTISQPAENSLELPSMTVPAPSTMTTTESPVVAVTEIPPVAVPEPPIMAVPelptmavvktPAVAVPE 1392
Cdd:PRK07994 351 MTLLrmlafHPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAV----------PLPETTS 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1393 PLVAAPEPPTMATPELcSLSVSEPPVAVSELPAlADPEHAITAVSGVSSLEPSVPILEPAVSVlqpvmivsEPSVPVQEP 1472
Cdd:PRK07994 421 QLLAARQQLQRAQGAT-KAKKSEPAAASRARPV-NSALERLASVRPAPSALEKAPAKKEAYRW--------KATNPVEVK 490
|
170 180
....*....|....*....|...
gi 338817942 1473 TVAVSEPAVIVSEHTQITSPEMA 1495
Cdd:PRK07994 491 KEPVATPKALKKALEHEKTPELA 513
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1311-1492 |
1.66e-05 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 50.42 E-value: 1.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1311 HAISEVTMSLLEPAVTISQPAEnsleLPSMTVPAPSTMTTTESPVVAVTEIPPVAVPEPPIMAV-PELPTMAVVKTPAVA 1389
Cdd:PRK10811 856 EEQREAEEVQVQPVVAEVPVAA----AVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETThPEVIAAPVTEQPQVI 931
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1390 VPEPLVAAPEPPTMATPelcslsVSEPPVAVSELPALADPEHAITAVSGVSSLEPSVPILEPAVSVLQPvmivsepsvPV 1469
Cdd:PRK10811 932 TESDVAVAQEVAEHAEP------VVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETV---------TA 996
|
170 180
....*....|....*....|...
gi 338817942 1470 QEPTVAVSEPAVIVSEHTQITSP 1492
Cdd:PRK10811 997 VEPEVAPAQVPEATVEHNHATAP 1019
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
203-456 |
1.82e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 50.71 E-value: 1.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 203 KPATKAAELSVVSTSVISEQSEQPMPGMLEPSMTKildsfTAAPVPMSTAALKSPEPVVTmsveyqksvlksLETMPPET 282
Cdd:PHA03247 2682 RPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALV-----SATPLPPGPAAARQASPALP------------AAPAPPAV 2744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 283 SKTTLVELPIAKVVEPSETLTIVSETPTEVHPEPSPSTMDFPESSTTDVQR--LPEQPVEAPSEIADSSMTRPQESLELP 360
Cdd:PHA03247 2745 PAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESResLPSPWDPADPPAAVLAPAAALPPAASP 2824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 361 KTTAVELQESTVASALELPGPPATSI-----------LELQGPPVTPVPELPGPSATPVPELSGPLSTPVPELPGPPATV 429
Cdd:PHA03247 2825 AGPLPPPTSAQPTAPPPPPGPPPPSLplggsvapggdVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQ 2904
|
250 260
....*....|....*....|....*..
gi 338817942 430 VPELPGPSVTPVPQLSQELPGPPAPSM 456
Cdd:PHA03247 2905 PERPPQPQAPPPPQPQPQPPPPPQPQP 2931
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1363-1481 |
2.20e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 49.71 E-value: 2.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1363 PVAVPEPPIMAVPELPTMAVVKTPAvAVPEPLVAAPEPPTMATPELCSLSVSEPPVAVSE---LPALADPEHAITAVSGV 1439
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPA-AAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPApvaAPAAAAPAAAPAAAPAA 444
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 338817942 1440 SSLEPSVPILEPAVSVLQPVMIVSEPSVPVQEPTVAVSEPAV 1481
Cdd:PRK14951 445 VALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAA 486
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
333-641 |
2.26e-05 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 50.06 E-value: 2.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 333 RLPEQPVEAPSEIADSSMTRPQESLELPKTTAVE-LQESTVASALELPGPPATSILElQGP---------------PVTP 396
Cdd:PHA03379 396 KLTERAREALEKASEPTYGTPRPPVEKPRPEVPQsLETATSHGSAQVPEPPPVHDLE-PGPlhdqhsmapcpvaqlPPGP 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 397 VP------ELPG------PSATPVPELSGPLSTP----VPELPG-PPATVVPE-LPGPSVtPVPQLSQELPGPPAPSMGL 458
Cdd:PHA03379 475 LQdlepgdQLPGvvqdgrPACAPVPAPAGPIVRPweasLSQVPGvAFAPVMPQpMPVEPV-PVPTVALERPVCPAPPLIA 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 459 EPPQEVPEPPVMAQELSGVPAVS-------AAIELTGQPA----------VTVAMELTEQPVTTTE--FEQPVAMTTVEH 519
Cdd:PHA03379 554 MQGPGETSGIVRVRERWRPAPWTpnpprspSQMSVRDRLArlraeaqpyqASVEVQPPQLTQVSPQqpMEYPLEPEQQMF 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 520 PGHP-----EVTTATGL--LGQPEAAMVLELP---GQPVATTALELSGQPSVTG-------VPELSGLPSATRALELSGQ 582
Cdd:PHA03379 634 PGSPfsqvaDVMRAGGVpaMQPQYFDLPLQQPisqGAPLAPLRASMGPVPPVPAtqpqyfdIPLTEPINQGASAAHFLPQ 713
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 338817942 583 SVATGALeLPGQLMATGALEFSGQSGAAGALELLGQPLATGVLElpGQPGAPELPGQPV 641
Cdd:PHA03379 714 QPMEGPL-VPERWMFQGATLSQSVRPGVAQSQYFDLPLTQPINH--GAPAAHFLHQPPM 769
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
315-672 |
3.35e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.40 E-value: 3.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 315 EPSPSTMDFPESSTTDVQRLPeQPVEAPSEIADSSMTRPQESL---ELPKTTAVELQESTVASALELP-GPPATSILELQ 390
Cdd:PHA03307 2 DNAPDLYDLIEAAAEGGEFFP-RPPATPGDAADDLLSGSQGQLvsdSAELAAVTVVAGAAACDRFEPPtGPPPGPGTEAP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 391 GPPVTPVPELPGPSATPVPELSGPLSTP--VPELPGPPATVVPELPGPSvtPVPQLSQELPGPPAPSmgleppqeVPEPP 468
Cdd:PHA03307 81 ANESRSTPTWSLSTLAPASPAREGSPTPpgPSSPDPPPPTPPPASPPPS--PAPDLSEMLRPVGSPG--------PPPAA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 469 VMAQELSGVPAVSAAIELTGQPAVTVAM-ELTEQPVTTTEFEQPVAMTTVEHPGHPEVttatglLGQPEAAMVLELPGQP 547
Cdd:PHA03307 151 SPPAAGASPAAVASDAASSRQAALPLSSpEETARAPSSPPAEPPPSTPPAAASPRPPR------RSSPISASASSPAPAP 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 548 VATTALELSGQPSVTGVPELSGLPSATRAlELSGQSVATGALELPGQLMATGALEFSG---QSGAAGALELLGQPlatgv 624
Cdd:PHA03307 225 GRSAADDAGASSSDSSSSESSGCGWGPEN-ECPLPRPAPITLPTRIWEASGWNGPSSRpgpASSSSSPRERSPSP----- 298
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 338817942 625 leLPGQPGAPELPGQPVAtVALEISVQSVVTTSELSTMTVSQSLEVPS 672
Cdd:PHA03307 299 --SPSSPGSGPAPSSPRA-SSSSSSSRESSSSSTSSSSESSRGAAVSP 343
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1272-1511 |
7.10e-05 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 48.37 E-value: 7.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1272 PMTYMVSETTMSVEPAVLTSEASVISETSETYDSMRPSGHAISEVTMSLlePAVT-----ISQPAEN--SLELPSMTVPA 1344
Cdd:pfam05109 400 PKTLIITRTATNATTTTHKVIFSKAPESTTTSPTLNTTGFAAPNTTTGL--PSSThvptnLTAPASTgpTVSTADVTSPT 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1345 PSTMTTTESPVVAvteiPPVAVPEPPIMAVPEL--PTMAVVK-TPAVAVPEPLVAAPEP----PTMATPELCSLSVSEPP 1417
Cdd:pfam05109 478 PAGTTSGASPVTP----SPSPRDNGTESKAPDMtsPTSAVTTpTPNATSPTPAVTTPTPnatsPTLGKTSPTSAVTTPTP 553
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1418 VAVSELPALADPEhaitavsgvsslePSVPIlePAVSVLQPVMIVSEPSVPVQEPTVAVSEPAVIVSEHT-QITSPEMAV 1496
Cdd:pfam05109 554 NATSPTPAVTTPT-------------PNATI--PTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTlGGTSSTPVV 618
|
250
....*....|....*
gi 338817942 1497 ESSPVIVDSSVMSSQ 1511
Cdd:pfam05109 619 TSPPKNATSAVTTGQ 633
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
247-516 |
7.41e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.40 E-value: 7.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 247 VPMSTAALKSPEPVVTmsveyqksvlkSLETMPPETSKTTLVELPIAKVVEPSETLTIVSETPTEVHPEPSPSTMDFPES 326
Cdd:PHA03247 2568 VPPPRPAPRPSEPAVT-----------SRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAN 2636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 327 STTDVQRLPEQPVEAPSEIADSSMTRPqeslelPKTTAVELQESTVASALELPGPPAT-----SILELQGPPVTPVPELP 401
Cdd:PHA03247 2637 EPDPHPPPTVPPPERPRDDPAPGRVSR------PRRARRLGRAAQASSPPQRPRRRAArptvgSLTSLADPPPPPPTPEP 2710
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 402 GP----SATPVPELSG------------PLSTPVPELPG----------PPATVVPELPGPSVTPVPQLSQELPGPPAPS 455
Cdd:PHA03247 2711 APhalvSATPLPPGPAaarqaspalpaaPAPPAVPAGPAtpggparparPPTTAGPPAPAPPAAPAAGPPRRLTRPAVAS 2790
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 338817942 456 MGLEPPQEVPEPPVmAQELSGVPAVSAAIELTGQPAVTVAMELTEQPVTTTEFEQPVAMTT 516
Cdd:PHA03247 2791 LSESRESLPSPWDP-ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL 2850
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1354-1503 |
9.58e-05 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 48.11 E-value: 9.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1354 PVVAVTEIPPVAVPEPPimavpelptmAVVKTPAVAVPEPLVAAPEPPTMATPELCSLSVSEPPVAVSELPALADP-EHA 1432
Cdd:PRK10811 846 PVVRPQDVQVEEQREAE----------EVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVvETT 915
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 338817942 1433 ITAVSGVSSLEPSVPILEPAVSVLQPVMIVSEPSVPVQEPTVAVSEPA----VIVSEHTQITSPEMAVESSPVIV 1503
Cdd:PRK10811 916 HPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAetaeVVVAEPEVVAQPAAPVVAEVAAE 990
|
|
| DSRM_A1CF |
cd19900 |
double-stranded RNA binding motif of APOBEC1 complementation factor (A1CF) and similar ... |
2388-2436 |
1.24e-04 |
|
double-stranded RNA binding motif of APOBEC1 complementation factor (A1CF) and similar proteins; A1CF (also known as APOBEC1-stimulating protein) is an essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the posttranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. A1CF binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. It contains three RNA recognition motifs (RRMs) and a C-terminal double-stranded RNA binding motif (DSRM) that is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380729 Cd Length: 81 Bit Score: 42.46 E-value: 1.24e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 338817942 2388 KHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRV--------LRNGSPYQPN 2436
Cdd:cd19900 1 KSPPQILEEICQKNNWGQPVYQLHSTIGPDQRQLFLYKVtipalasqYPNITPFQPN 57
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1191-1393 |
1.82e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 46.96 E-value: 1.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1191 TEVTLSTGESLSQPEPPVSQSEISEPMAVPAnysmsesETSMLASEAVMTVPEPAREPEssVTSAPVESAVVAEHEMVPE 1270
Cdd:PRK10811 848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAA-------VEPVVSAPVVEAVAEVVEEPV--VVAEPQPEEVVVVETTHPE 918
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1271 rpmtymVSETTMSVEPAVLT-SEASVISETSETydsmrpsGHAISEVtmsllEPAVTISQPAENSLElpsMTVPAPSTMT 1349
Cdd:PRK10811 919 ------VIAAPVTEQPQVITeSDVAVAQEVAEH-------AEPVVEP-----QDETADIEEAAETAE---VVVAEPEVVA 977
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 338817942 1350 TTESPVVAVTEIPPVAVPEPPIMAVPELPTMAVV----------KTPAVA-VPEP 1393
Cdd:PRK10811 978 QPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVehnhatapmtRAPAPEyVPEA 1032
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1213-1418 |
2.46e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 46.57 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1213 ISEPMAVPANYSMSESETSMLASEAVMTVPEPAREPESSVTSAPVESAVVAehemVPERPMTymVSETTMSVEPAVLTSE 1292
Cdd:PRK10811 843 IRYPVVRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAE----VVEEPVV--VAEPQPEEVVVVETTH 916
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1293 ASVISETSETydsmrpSGHAISEVTMSLLEPAVTISQPAEnslelpsmtvpapsTMTTTESPVVAVTEIPPVAVPEPPim 1372
Cdd:PRK10811 917 PEVIAAPVTE------QPQVITESDVAVAQEVAEHAEPVV--------------EPQDETADIEEAAETAEVVVAEPE-- 974
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 338817942 1373 avpelptmAVVKTPAVAVPEPLVAAPEPPTmATPELCSLSVSEPPV 1418
Cdd:PRK10811 975 --------VVAQPAAPVVAEVAAEVETVTA-VEPEVAPAQVPEATV 1011
|
|
| DSRM_PRKRA-like_rpt1 |
cd19862 |
first double-stranded RNA binding motif of protein activator of the interferon-induced protein ... |
2388-2426 |
3.11e-04 |
|
first double-stranded RNA binding motif of protein activator of the interferon-induced protein kinase (PRKRA) and similar proteins; This family includes protein activator of the interferon-induced protein kinase (PRKRA) and the RISC-loading complex subunit TARBP2. PRKRA (also known as interferon-inducible double-stranded RNA-dependent protein kinase activator A, PKR-associated protein X (RAX), PKR-associating protein X, protein kinase, interferon-inducible double-stranded RNA-dependent activator, PACT, or HSD14) is a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling. TARBP2 (also called TAR RNA-binding protein 2, or trans-activation-responsive RNA-binding protein (TRBP)), participates in the formation of the RNA-induced silencing complex (RISC). It is part of the RISC-loading complex (RLC), together with dicer1 and eif2c2/ago2, and is required to process precursor miRNAs. This family also includes Drosophila melanogaster Loquacious and similar proteins. Loquacious (Loqs) is a double-stranded RNA-binding domain (dsRBD) protein, a homolog of human TAR RNA binding protein (TRBP) that is a protein first identified as binding the HIV trans-activator RNA (TAR). Loqs interacts with Dicer1 (dmDcr1) to facilitate miRNA processing. PRKRA family proteins contain three double-stranded RNA binding motifs (DSRMs). This model describes the first motif. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380691 [Multi-domain] Cd Length: 70 Bit Score: 41.09 E-value: 3.11e-04
10 20 30
....*....|....*....|....*....|....*....
gi 338817942 2388 KHPVSALMEICNKRRWqPPEFLLVHDSGPDHRKHFLFRV 2426
Cdd:cd19862 1 KTPISVLQELCAKRGI-TPKYELISSEGAVHEPTFTFRV 38
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
82-574 |
3.26e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 46.30 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 82 DLKEASRKSRCVSV--QTDPTDEVPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESE--SKLKSHHDGNLESDSFLKFD 157
Cdd:pfam03154 38 DLRSSGRNSPSAAStsSNDSKAESMKKSSKKIKEEAPSPLKSAKRQREKGASDTEEPEraTAKKSKTQEISRPNSPSEGE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 158 SEPSAAALEHPVRAFGLSEASETALVLEPPVVSMEVQESHvletlkpATKAAELSVVSTSVISEQSEQPMPGMLEPSMTK 237
Cdd:pfam03154 118 GESSDGRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESD-------SDSSAQQQILQTQPPVLQAQSGAASPPSPPPPG 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 238 ILDSFTAAPVPMSTAALKSPEPVVTMSVEYQKSvlksleTMPPETSKTTLVELPIAKVVEPSETLTIV------SETPTE 311
Cdd:pfam03154 191 TTQAATAGPTPSAPSVPPQGSPATSQPPNQTQS------TAAPHTLIQQTPTLHPQRLPSPHPPLQPMtqppppSQVSPQ 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 312 VHPEPSPSTMDFP-----ESSTTDVQR-LPEQPVEAPSEIADS------SMTRPQESLELPKTTAVELQESTVASALELP 379
Cdd:pfam03154 265 PLPQPSLHGQMPPmphslQTGPSHMQHpVPPQPFPLTPQSSQSqvppgpSPAAPGQSQQRIHTPPSQSQLQSQQPPREQP 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 380 GPPA-TSILELQGPPVTPVPELPGPSATPVP-ELSGPLSTPVP-ELPGPPA----TVVPELPGPSVTPVP-QL---SQEL 448
Cdd:pfam03154 345 LPPApLSMPHIKPPPTTPIPQLPNPQSHKHPpHLSGPSPFQMNsNLPPPPAlkplSSLSTHHPPSAHPPPlQLmpqSQQL 424
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 449 PGPPAPSMGLEPPQEVPEPPVMAQELSGVPAVSAAIELTGQPAVTVAMELTEQPvTTTEFEQPVAMTTVEHPGHPEVTTA 528
Cdd:pfam03154 425 PPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPP-SGPPTSTSSAMPGIQPPSSASVSSS 503
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 338817942 529 TGLLGQPEAAmvleLPGQPVATTALELSGQPSVTGVPELSGLPSAT 574
Cdd:pfam03154 504 GPVPAAVSCP----LPPVQIKEEALDEAEEPESPPPPPRSPSPEPT 545
|
|
| DSRM_A1CF-like |
cd19872 |
double-stranded RNA binding motif of APOBEC1 complementation factor (A1CF), RNA-binding ... |
2389-2436 |
4.09e-04 |
|
double-stranded RNA binding motif of APOBEC1 complementation factor (A1CF), RNA-binding protein 46 (RBM46) and similar proteins; The family includes two dsRNA-binding motif-containing proteins, A1CF and RBM46. A1CF (also known as APOBEC1-stimulating protein) is an essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the posttranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. A1CF binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. RBM46 (also called cancer/testis antigen 68 (CT68), or RNA-binding motif protein 46) plays a novel role in the regulation of embryonic stem cell (ESC) differentiation by regulating the degradation of beta-catenin mRNA. It also regulates trophectoderm specification by stabilizing Cdx2 mRNA in early mouse embryos. Members of this family contain three RNA recognition motifs (RRMs) and a C-terminal double-stranded RNA binding motif (DSRM) that is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380701 Cd Length: 75 Bit Score: 41.12 E-value: 4.09e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 338817942 2389 HPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPYQPN 2436
Cdd:cd19872 1 NPVQILEEICQKNGWGEPVYQLLSTSSNNEVQLFIYKVTIPNLPNGRL 48
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1317-1500 |
5.49e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 45.23 E-value: 5.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1317 TMSLL-----EPAVTI-SQPAENSLELPSMTVPAPSTMTTTESPVVAVTEIPPVAVPePPIMAVPE--LPTMAVVKTPAV 1388
Cdd:PRK07003 349 TMTLLrmlafEPAVTGgGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGA-AGAALAPKaaAAAAATRAEAPP 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1389 AVPEPLVAAPEPPTMATPELCSLSVSEPPVAVSELPALAD--PEHAITAVSGVSSLEPSVPILEPAVSVLQPVMIVSEPS 1466
Cdd:PRK07003 428 AAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDaqPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAV 507
|
170 180 190
....*....|....*....|....*....|....*.
gi 338817942 1467 VPVQEPTVA--VSEPAVIVSEHTQITSPEMAVESSP 1500
Cdd:PRK07003 508 PDARAPAAAsrEDAPAAAAPPAPEARPPTPAAAAPA 543
|
|
| DSRM_DRADA |
cd19902 |
double-stranded RNA binding motif of double-stranded RNA-specific adenosine deaminase (DRADA) ... |
2388-2433 |
1.17e-03 |
|
double-stranded RNA binding motif of double-stranded RNA-specific adenosine deaminase (DRADA) and similar proteins; DRADA (EC 3.5.4.37; also known as 136 kDa double-stranded RNA-binding protein (p136), interferon-inducible protein 4 (IFI-4), K88DSRBP, ADAR1, G1P1, or ADAR) catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA), referred to as A-to-I RNA editing. DRADA family members contain at least one double-stranded RNA binding motifs (DSRM); vertebrate proteins contain three. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380731 Cd Length: 71 Bit Score: 39.58 E-value: 1.17e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 338817942 2388 KHPVSALMEICNKRRwQPPEFLLVHDSGPDHRKHFLFRVLRNGSPY 2433
Cdd:cd19902 1 KNPVSALMEYAQSRG-VTAEIEVLSQSGPPHNPRFKAAVFVGGRRF 45
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
1254-1439 |
1.47e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 43.87 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1254 SAPVesAVVAEHEMVPERPmtymvsETTMSVEPAVLTSEASVISETSETYDSMRpsghaisEVTMSLLEPAVTISQPAEN 1333
Cdd:PRK10811 844 RYPV--VRPQDVQVEEQRE------AEEVQVQPVVAEVPVAAAVEPVVSAPVVE-------AVAEVVEEPVVVAEPQPEE 908
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1334 SLELPSMTVPAPSTMTTTESPVVAVTEIPPVAVPEPPIMAVPELPTMAVVKTPAVAVPEPLVAAPEPPTMATPElcslSV 1413
Cdd:PRK10811 909 VVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAP----VV 984
|
170 180
....*....|....*....|....*.
gi 338817942 1414 SEPPVAVSELPALADPEHAITAVSGV 1439
Cdd:PRK10811 985 AEVAAEVETVTAVEPEVAPAQVPEAT 1010
|
|
| DSRM_EIF2AK2-like |
cd19875 |
double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 ... |
2388-2437 |
1.60e-03 |
|
double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins; The family includes EIF2AK2 and adenosine deaminase domain-containing proteins, ADAD1 and ADAD2. EIF2AK2 (EC 2.7.11.1/EC 2.7.10.2; also known as interferon-induced, double-stranded RNA-activated protein kinase, eIF-2A protein kinase 2, interferon-inducible RNA-dependent protein kinase, P1/eIF-2A protein kinase, protein kinase RNA-activated (PKR), protein kinase R, tyrosine-protein kinase EIF2AK2, or p68 kinase) acts as an IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. ADAD1 (also called testis nuclear RNA-binding protein (TENR)) and ADAD2 (also called testis nuclear RNA-binding protein-like (TENRL)) are phylogenetically related to a family of adenosine deaminases involved in RNA editing. ADAD1 plays an essential function in spermatid morphogenesis. It may be involved in testis-specific nuclear post-transcriptional processes such as heterogeneous nuclear RNA (hnRNA) packaging, alternative splicing, or nuclear/cytoplasmic transport of mRNAs. ADAD2 is a double-stranded RNA binding protein with unclear biological function. Members of this group contains varying numbers of double-stranded RNA binding motifs (DSRMs). DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380704 Cd Length: 67 Bit Score: 39.17 E-value: 1.60e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 338817942 2388 KHPVSALMEICNKRRwQPPEFLLVhDSGPDHRKHFLFRVLRNGSPYQPNC 2437
Cdd:cd19875 1 KNPVSALNEYCQKRG-LSLEFVDV-SVGPDHCPGFTASATIDGIVFASAT 48
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1314-1481 |
2.04e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 43.41 E-value: 2.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1314 SEVTMSLLEPAVTISQPAENSLELPSMTVPAPSTMTTTESPVVAVTEipPVAVPEPPIMAVpELPTMAVVKTPAVAVPEP 1393
Cdd:pfam17823 84 TEVTAEHTPHGTDLSEPATREGAADGAASRALAAAASSSPSSAAQSL--PAAIAALPSEAF-SAPRAAACRANASAAPRA 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1394 LVAAPEPPTMATPELCSlSVSEPPVAVSELPALADPEHAitAVSGVSSLEPSVPILEPAVSVLQPVMIVSEPSVPVQEPT 1473
Cdd:pfam17823 161 AIAAASAPHAASPAPRT-AASSTTAASSTTAASSAPTTA--ASSAPATLTPARGISTAATATGHPAAGTALAAVGNSSPA 237
|
....*...
gi 338817942 1474 VAVSEPAV 1481
Cdd:pfam17823 238 AGTVTAAV 245
|
|
| DSRM_DRADA_rpt1 |
cd19913 |
first double-stranded RNA binding motif of double-stranded RNA-specific adenosine deaminase ... |
2388-2435 |
2.33e-03 |
|
first double-stranded RNA binding motif of double-stranded RNA-specific adenosine deaminase (DRADA); DRADA (EC 3.5.4.37; also known as 136 kDa double-stranded RNA-binding protein (p136), interferon-inducible protein 4 (IFI-4), K88DSRBP, ADAR1, G1P1, or ADAR) catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA), referred to as A-to-I RNA editing. Vertebrate DRADA contains three double-stranded RNA binding motifs (DSRMs). This model describes the first motif. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380742 Cd Length: 71 Bit Score: 38.70 E-value: 2.33e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 338817942 2388 KHPVSALMEICnKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPYQP 2435
Cdd:cd19913 1 KNPVSGLMEYA-QFLGQTCEFLLLEQSGPSHDPRFKFQAVIDGRRFPP 47
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1176-1512 |
3.10e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 42.64 E-value: 3.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1176 LSTEQSALTADNTWSTEVTLSTGESLSQPeppvsqsEISEPMAVPANYSMSESETSMLASEAVMTVPEPAREPESSVTSA 1255
Cdd:pfam17823 72 LTKGTSAAHLNSTEVTAEHTPHGTDLSEP-------ATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSEAFSA 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1256 PVESAVVAEHEMVPERPMTYMVSETTMSvePAVLTSEASVISETSETYDSMRPSGHAISevTMSLLEPAVTISQPAensl 1335
Cdd:pfam17823 145 PRAAACRANASAAPRAAIAAASAPHAAS--PAPRTAASSTTAASSTTAASSAPTTAASS--APATLTPARGISTAA---- 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1336 elpsmtvpapsTMTTTESPVVAVTEIPPVAVPEPPIMAVPELPTMAVVKTPAVAVpEPLVAAPEPPTMATPELCSLSVSE 1415
Cdd:pfam17823 217 -----------TATGHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAALATLAAAA-GTVASAAGTINMGDPHARRLSPAK 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1416 --PPVAVSELPALADPEHAITAVSGVSSLEPSVPIL-EPAVSvlqPVMIVSEPSVPvqePTVAVSEPAVIVSEHTQITSP 1492
Cdd:pfam17823 285 hmPSDTMARNPAAPMGAQAQGPIIQVSTDQPVHNTAgEPTPS---PSNTTLEPNTP---KSVASTNLAVVTTTKAQAKEP 358
|
330 340
....*....|....*....|
gi 338817942 1493 emavESSPVIVDSSVMSSQI 1512
Cdd:pfam17823 359 ----SASPVPVLHTSMIPEV 374
|
|
| Rnc |
COG0571 |
dsRNA-specific ribonuclease [Transcription]; |
2380-2433 |
3.11e-03 |
|
dsRNA-specific ribonuclease [Transcription];
Pssm-ID: 440336 [Multi-domain] Cd Length: 229 Bit Score: 41.62 E-value: 3.11e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 338817942 2380 AAMKDLSGKHPVSALMEICNKRRWQPPEFLLVHDSGPDHRKHFLFRVLRNGSPY 2433
Cdd:COG0571 149 EIAPGGAGKDYKTALQEWLQARGLPLPEYEVVEEEGPDHAKTFTVEVLVGGKVL 202
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
246-458 |
4.31e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.22 E-value: 4.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 246 PVPMSTAALKSPEPVVTMSVEYQKSVLKSLETmPPEtskttlvelPIAKVVEPSETLTIVSETPTEVHPEPSPSTMDFPE 325
Cdd:PLN03209 328 VPPKESDAADGPKPVPTKPVTPEAPSPPIEEE-PPQ---------PKAVVPRPLSPYTAYEDLKPPTSPIPTPPSSSPAS 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 326 SSTTDVQRLPEQPVEAPSeiADSSMTRPQ-ESLELPKTTAVELQESTVASALELP-----------GPPATSILELQGPP 393
Cdd:PLN03209 398 SKSVDAVAKPAEPDVVPS--PGSASNVPEvEPAQVEAKKTRPLSPYARYEDLKPPtspsptaptgvSPSVSSTSSVPAVP 475
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 338817942 394 VTPVPELPGPSATPVPELSGPLST-PVPELPGPPATVVPELPGPSVTPVPQLSQELPGPPAPSMGL 458
Cdd:PLN03209 476 DTAPATAATDAAAPPPANMRPLSPyAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTAL 541
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
382-553 |
4.62e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.16 E-value: 4.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 382 PATSILELQGPPVTPVPeLPGPSATPVPELSGPLSTPVPELPGPPATVVPELPGPSVTPVPQLSQELPGPPAPSMGLEPP 461
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAP-AASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAK 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 462 QEVPEPPVMAQELSGV-----PAVSAAIELTGQPAVTVAMELTEQP---VTTTEFEQPVAMT-TVEHPGHPEVTTATGLL 532
Cdd:PRK07994 440 KSEPAAASRARPVNSAlerlaSVRPAPSALEKAPAKKEAYRWKATNpveVKKEPVATPKALKkALEHEKTPELAAKLAAE 519
|
170 180
....*....|....*....|....*.
gi 338817942 533 GQPE---AAMV--LELPGqPVATTAL 553
Cdd:PRK07994 520 AIERdpwAALVsqLGLPG-LVEQLAL 544
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
375-455 |
4.74e-03 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 41.36 E-value: 4.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 375 ALELPGPPAtSILELQGPPVTPVPELPGPSATPVPELSGPLSTPVPELPGPPATVVPELPgPSVTPVPQLSQELPGPPAP 454
Cdd:PLN02983 140 ALPQPPPPA-PVVMMQPPPPHAMPPASPPAAQPAPSAPASSPPPTPASPPPAKAPKSSHP-PLKSPMAGTFYRSPAPGEP 217
|
.
gi 338817942 455 S 455
Cdd:PLN02983 218 P 218
|
|
| DSRM_DRADA_rpt2 |
cd19914 |
second double-stranded RNA binding motif of double-stranded RNA-specific adenosine deaminase ... |
2388-2426 |
5.31e-03 |
|
second double-stranded RNA binding motif of double-stranded RNA-specific adenosine deaminase (DRADA) and similar proteins; DRADA (EC 3.5.4.37; also known as 136 kDa double-stranded RNA-binding protein (p136), interferon-inducible protein 4 (IFI-4), K88DSRBP, ADAR1, G1P1, or ADAR) catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA), referred to as A-to-I RNA editing. Vertebrate DRADA contains three double-stranded RNA binding motifs (DSRMs). This model describes the second motif. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380743 Cd Length: 71 Bit Score: 37.52 E-value: 5.31e-03
10 20 30
....*....|....*....|....*....|....*....
gi 338817942 2388 KHPVSALMEiCNKRRWQPPEFLLVHDSGPDHRKHFLFRV 2426
Cdd:cd19914 1 KNPISVLME-HSQKSGNMCEFQLLSQEGPPHDPKFTYCV 38
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
1342-1445 |
6.07e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.01 E-value: 6.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1342 VPAPSTMTTTESPVVAVTEIPPVAVPEPPIMAVPELPTMAVVKTPAVA-VPEPLVAAPEPPTMATPElcslsVSEPPVAV 1420
Cdd:PRK14951 392 APVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAaAPAAVALAPAPPAQAAPE-----TVAIPVRV 466
|
90 100
....*....|....*....|....*
gi 338817942 1421 SELPALADPEHAITAVSGVSSLEPS 1445
Cdd:PRK14951 467 APEPAVASAAPAPAAAPAAARLTPT 491
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
243-423 |
9.83e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 41.18 E-value: 9.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 243 TAAPVPMSTAAlKSPE----------PVVTmsVEYQKSVLKSLETMPPETskTTLVELPIAKVVEPSETLTIVSETPTEV 312
Cdd:PRK10811 821 TQSPMPLTVAC-ASPEmasgkvwiryPVVR--PQDVQVEEQREAEEVQVQ--PVVAEVPVAAAVEPVVSAPVVEAVAEVV 895
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 313 HPEP---SPSTMDFPESSTTDVQRLPEQPVEAPSEIADSSMTRPQESLELPK-TTAVELQESTVASALELPGPPATSILE 388
Cdd:PRK10811 896 EEPVvvaEPQPEEVVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEpVVEPQDETADIEEAAETAEVVVAEPEV 975
|
170 180 190
....*....|....*....|....*....|....*
gi 338817942 389 LQGPPVTPVPELPGPSATPVPELSGPLSTPVPELP 423
Cdd:PRK10811 976 VAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEAT 1010
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
1307-1447 |
9.87e-03 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 40.61 E-value: 9.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 338817942 1307 RPSGHaisevtmSLLEPAVTISQPAENSlelPSMTVPAPSTMTTTESPVVAVTEIPPVAVPEPPIMAVPELPTMAVVKTP 1386
Cdd:PHA02682 75 RPSGQ-------SPLAPSPACAAPAPAC---PACAPAAPAPAVTCPAPAPACPPATAPTCPPPAVCPAPARPAPACPPST 144
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 338817942 1387 AVAVPEPLVAAPEPPTMATPELCSLSVSEPPVAVSELPALAdpehaiTAVSGVSSLEPSVP 1447
Cdd:PHA02682 145 RQCPPAPPLPTPKPAPAAKPIFLHNQLPPPDYPAASCPTIE------TAPAASPVLEPRIP 199
|
|
| DSRM_TARBP2_rpt2 |
cd10844 |
second double-stranded RNA binding motif of the RISC-loading complex subunit TARBP2 and ... |
2390-2422 |
9.90e-03 |
|
second double-stranded RNA binding motif of the RISC-loading complex subunit TARBP2 and similar proteins; TARBP2 (also known as TAR RNA-binding protein 2, or trans-activation-responsive RNA-binding protein (TRBP)) participates in the formation of the RNA-induced silencing complex (RISC). It is part of the RISC-loading complex (RLC), together with dicer1 and eif2c2/ago2, and is required to process precursor miRNAs. TARBP2 contains three double-stranded RNA binding motifs (DSRMs). This model describes the second motif. DSRM is not sequence specific, but highly specific for dsRNAs of various origin and structure.
Pssm-ID: 380681 Cd Length: 67 Bit Score: 37.01 E-value: 9.90e-03
10 20 30
....*....|....*....|....*....|...
gi 338817942 2390 PVSALMEICNKRRWQPPEFLLVHDSGPDHRKHF 2422
Cdd:cd10844 2 PVGALQELVVQKGWRLPEYTVTQESGPAHRKEF 34
|
|
| |
