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Conserved domains on  [gi|18203514|sp|Q9UUJ7|]
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RecName: Full=COP9 signalosome complex subunit 7

Protein Classification

PCI domain-containing protein( domain architecture ID 2851)

PCI (proteasome-COP9/CSN-initiation factor) domain-containing protein is a component of multiprotein complexes; Similar to Schizosaccharomyces pombe COP9 signalosome complex subunit 7 and Mus musculus PCI domain-containing protein 2

Gene Ontology:  GO:0000338|GO:0003690
PubMed:  9644972

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PINT super family cl02111
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 56-151 8.78e-04

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


The actual alignment was detected with superfamily member smart00088:

Pssm-ID: 470471 [Multi-domain]  Cd Length: 88  Bit Score: 37.22  E-value: 8.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18203514     56 WNELRfKKLRLLTLIDLANRHvgSSVSFETILVHLQLDRlppsdptFTVEYYIMQAMMNQILVGKINAKTQTLHVSWALE 135
Cdd:smart00088   3 VERLQ-RKIRLTNLLQLSEPY--SSISLSDLAKLLGLSV-------PEVEKLVSKAIRDGEISAKIDQVNGIVEFEEVDP 72

                           90
                   ....*....|....*.
gi 18203514    136 RflDSKRIDEMKYSLD 151
Cdd:smart00088  73 R--RSEPLAQFAETLK 86
 
Name Accession Description Interval E-value
PINT smart00088
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 56-151 8.78e-04

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


Pssm-ID: 214509 [Multi-domain]  Cd Length: 88  Bit Score: 37.22  E-value: 8.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18203514     56 WNELRfKKLRLLTLIDLANRHvgSSVSFETILVHLQLDRlppsdptFTVEYYIMQAMMNQILVGKINAKTQTLHVSWALE 135
Cdd:smart00088   3 VERLQ-RKIRLTNLLQLSEPY--SSISLSDLAKLLGLSV-------PEVEKLVSKAIRDGEISAKIDQVNGIVEFEEVDP 72

                           90
                   ....*....|....*.
gi 18203514    136 RflDSKRIDEMKYSLD 151
Cdd:smart00088  73 R--RSEPLAQFAETLK 86
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 56-132 3.55e-03

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


Pssm-ID: 460195  Cd Length: 105  Bit Score: 35.66  E-value: 3.55e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18203514    56 WNELRfKKLRLLTLIDLANRHvgSSVSFETILVHLQLdrlppsdPTFTVEYYIMQAMMNQILVGKINAKTQTLHVSW 132
Cdd:pfam01399  39 LEDLR-RKIREHNLRQLSKPY--SSISLSDLAKLLGL-------SVDEVEKILAKLIRDGRIRAKIDQVNGIVVFSK 105
 
Name Accession Description Interval E-value
PINT smart00088
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 56-151 8.78e-04

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


Pssm-ID: 214509 [Multi-domain]  Cd Length: 88  Bit Score: 37.22  E-value: 8.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18203514     56 WNELRfKKLRLLTLIDLANRHvgSSVSFETILVHLQLDRlppsdptFTVEYYIMQAMMNQILVGKINAKTQTLHVSWALE 135
Cdd:smart00088   3 VERLQ-RKIRLTNLLQLSEPY--SSISLSDLAKLLGLSV-------PEVEKLVSKAIRDGEISAKIDQVNGIVEFEEVDP 72

                           90
                   ....*....|....*.
gi 18203514    136 RflDSKRIDEMKYSLD 151
Cdd:smart00088  73 R--RSEPLAQFAETLK 86
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 56-132 3.55e-03

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


Pssm-ID: 460195  Cd Length: 105  Bit Score: 35.66  E-value: 3.55e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18203514    56 WNELRfKKLRLLTLIDLANRHvgSSVSFETILVHLQLdrlppsdPTFTVEYYIMQAMMNQILVGKINAKTQTLHVSW 132
Cdd:pfam01399  39 LEDLR-RKIREHNLRQLSKPY--SSISLSDLAKLLGL-------SVDEVEKILAKLIRDGRIRAKIDQVNGIVVFSK 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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