NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1679351195|sp|Q9XX11|]
View 

RecName: Full=ATP synthase subunit C lysine N-methyltransferase

Protein Classification

methyltransferase domain-containing protein( domain architecture ID 1012635)

methyltransferase domain-containing protein similar to Caenorhabditis elegans small RNA 2'-O-methyltransferase that adds a 2'-O-methyl group at the 3'-end of PIWI-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) which are classes of regulatory RNAs that are involved in gene silencing in endogenous RNA interference (RNAi) pathways

EC:  2.1.1.-
Gene Ontology:  GO:0008168|GO:0032259
PubMed:  22536158

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
UbiG super family cl34436
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 64-105 8.72e-04

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


The actual alignment was detected with superfamily member COG2227:

Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 37.69  E-value: 8.72e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1679351195  64 KKGTLIDLGSGDGRVVLQCAREGFNSTGVELNSILVAYSKYR 105
Cdd:COG2227    24 AGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARER 65
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 64-105 8.72e-04

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 37.69  E-value: 8.72e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1679351195  64 KKGTLIDLGSGDGRVVLQCAREGFNSTGVELNSILVAYSKYR 105
Cdd:COG2227    24 AGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARER 65
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 69-111 4.07e-03

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 35.33  E-value: 4.07e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1679351195  69 IDLGSGDGRVVLQCAREGFNSTGVELNSILVAYSKYRSIREGL 111
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGL 43
 
Name Accession Description Interval E-value
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 64-105 8.72e-04

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 37.69  E-value: 8.72e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1679351195  64 KKGTLIDLGSGDGRVVLQCAREGFNSTGVELNSILVAYSKYR 105
Cdd:COG2227    24 AGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARER 65
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 69-111 4.07e-03

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 35.33  E-value: 4.07e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1679351195  69 IDLGSGDGRVVLQCAREGFNSTGVELNSILVAYSKYRSIREGL 111
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGL 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH