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Conserved domains on  [gi|1751002388|gb|QET68492|]
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HTH-type transcriptional regulator [Citrobacter werkmanii]

Protein Classification

transcriptional regulator( domain architecture ID 10793339)

helix-turn-helix-type transcriptional regulator

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10072 PRK10072
HTH-type transcriptional regulator;
1-96 6.38e-62

HTH-type transcriptional regulator;


:

Pssm-ID: 182222  Cd Length: 96  Bit Score: 183.07  E-value: 6.38e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751002388  1 MEYKDPMFELLSSLEQIVFKDVSQTVTLTQKTNPFTEFEQLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKL 80
Cdd:PRK10072   1 MEYKDPMFELLSSLEQIVFKDETQKITLTQKTTSFTEFEQLRKGTGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKL 80

                         90
                 ....*....|....*.
gi 1751002388 81 MRLIQADPRLSKQLMD 96
Cdd:PRK10072  81 MRLIQANPALSKQLME 96
 
Name Accession Description Interval E-value
PRK10072 PRK10072
HTH-type transcriptional regulator;
1-96 6.38e-62

HTH-type transcriptional regulator;


Pssm-ID: 182222  Cd Length: 96  Bit Score: 183.07  E-value: 6.38e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751002388  1 MEYKDPMFELLSSLEQIVFKDVSQTVTLTQKTNPFTEFEQLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKL 80
Cdd:PRK10072   1 MEYKDPMFELLSSLEQIVFKDETQKITLTQKTTSFTEFEQLRKGTGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKL 80

                         90
                 ....*....|....*.
gi 1751002388 81 MRLIQADPRLSKQLMD 96
Cdd:PRK10072  81 MRLIQANPALSKQLME 96
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
29-90 4.12e-14

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 61.10  E-value: 4.12e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1751002388 29 TQKTNPFTEFEQLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLMRLIQADPRL 90
Cdd:COG2944    2 TKKPLTPEEIRALRERLGLSQAEFAALLGVSVSTVRRWEQGRRKPSGAALKLLRLLEKHPEL 63
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 37-94 7.41e-05

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 38.77  E-value: 7.41e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1751002388  37 EFEQLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLMRLIQADPRLSKQL 94
Cdd:TIGR03830  69 EIRRIRKKLGLSQREAAELLGGGVNAFSRYERGEVRPSKALDKLLRLLDKHPELLEEL 126
NadS NF041265
NadS family protein;
9-94 1.13e-04

NadS family protein;


Pssm-ID: 469165  Cd Length: 94  Bit Score: 37.46  E-value: 1.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751002388  9 ELLSSLEQIVfkDVSQTVtltQKTNPFTEFE-----QLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLMRL 83
Cdd:NF041265   6 ELKASLEEAV--EIKNGV---KAPARVTRYEvadvkAIRAQLNVSQAEMAKALGTSVDTIKSWESKRRNPTGLAAKVLAT 80

                         90
                 ....*....|.
gi 1751002388 84 IQADPRLSKQL 94
Cdd:NF041265  81 IQDNPAFFKEL 91
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 40-81 3.93e-04

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 35.22  E-value: 3.93e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 1751002388 40 QLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLM 81
Cdd:cd00093    6 ELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKL 47
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
40-81 3.99e-04

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 35.19  E-value: 3.99e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1751002388  40 QLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLM 81
Cdd:smart00530  4 ELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKL 45
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 37-90 5.11e-03

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 32.50  E-value: 5.11e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 1751002388 37 EFEQLRRGTGLKTDDFARVMGVTVAMVHEWES-KRVKPSTTEL-KLMRLIQADPRL 90
Cdd:pfam13560  5 RLRRLRERAGLSQEALARRLGVSRSTLSRLETgRRGRPSPAVVeRLARALGVDGAE 60
 
Name Accession Description Interval E-value
PRK10072 PRK10072
HTH-type transcriptional regulator;
1-96 6.38e-62

HTH-type transcriptional regulator;


Pssm-ID: 182222  Cd Length: 96  Bit Score: 183.07  E-value: 6.38e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751002388  1 MEYKDPMFELLSSLEQIVFKDVSQTVTLTQKTNPFTEFEQLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKL 80
Cdd:PRK10072   1 MEYKDPMFELLSSLEQIVFKDETQKITLTQKTTSFTEFEQLRKGTGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKL 80

                         90
                 ....*....|....*.
gi 1751002388 81 MRLIQADPRLSKQLMD 96
Cdd:PRK10072  81 MRLIQANPALSKQLME 96
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
29-90 4.12e-14

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 61.10  E-value: 4.12e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1751002388 29 TQKTNPFTEFEQLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLMRLIQADPRL 90
Cdd:COG2944    2 TKKPLTPEEIRALRERLGLSQAEFAALLGVSVSTVRRWEQGRRKPSGAALKLLRLLEKHPEL 63
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 37-94 7.41e-05

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 38.77  E-value: 7.41e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1751002388  37 EFEQLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLMRLIQADPRLSKQL 94
Cdd:TIGR03830  69 EIRRIRKKLGLSQREAAELLGGGVNAFSRYERGEVRPSKALDKLLRLLDKHPELLEEL 126
NadS NF041265
NadS family protein;
9-94 1.13e-04

NadS family protein;


Pssm-ID: 469165  Cd Length: 94  Bit Score: 37.46  E-value: 1.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1751002388  9 ELLSSLEQIVfkDVSQTVtltQKTNPFTEFE-----QLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLMRL 83
Cdd:NF041265   6 ELKASLEEAV--EIKNGV---KAPARVTRYEvadvkAIRAQLNVSQAEMAKALGTSVDTIKSWESKRRNPTGLAAKVLAT 80

                         90
                 ....*....|.
gi 1751002388 84 IQADPRLSKQL 94
Cdd:NF041265  81 IQDNPAFFKEL 91
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 40-81 3.93e-04

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 35.22  E-value: 3.93e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 1751002388 40 QLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLM 81
Cdd:cd00093    6 ELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLETLEKL 47
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
40-81 3.99e-04

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 35.19  E-value: 3.99e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1751002388  40 QLRRGTGLKTDDFARVMGVTVAMVHEWESKRVKPSTTELKLM 81
Cdd:smart00530  4 ELREEKGLTQEELAEKLGVSRSTLSRIENGKRKPSLETLKKL 45
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 37-90 5.11e-03

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 32.50  E-value: 5.11e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 1751002388 37 EFEQLRRGTGLKTDDFARVMGVTVAMVHEWES-KRVKPSTTEL-KLMRLIQADPRL 90
Cdd:pfam13560  5 RLRRLRERAGLSQEALARRLGVSRSTLSRLETgRRGRPSPAVVeRLARALGVDGAE 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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