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Conserved domains on  [gi|1784287334|gb|QGW85137|]
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50S ribosomal protein L29 [Variovorax paradoxus]

Protein Classification

50S ribosomal protein L29( domain architecture ID 10000811)

50S ribosomal protein L29 binds 23S rRNA and is not essential for growth; it is one of the proteins that surrounds the polypeptide exit tunnel on the outside of the 50s ribosomal subunit

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RpmC COG0255
Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 ...
3-62 3.47e-17

Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 is part of the Pathway/BioSystem: Ribosome 50S subunit


:

Pssm-ID: 440025 [Multi-domain]  Cd Length: 65  Bit Score: 67.84  E-value: 3.47e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784287334  3 KAATLRTKDVAGLQAEIKDLQKAHFGLRMQKATQQLSNTSTLRVTRRDIARAKTILAQKQ 62
Cdd:COG0255    2 KAKELRELSDEELKEKLKELKKELFNLRFQHATGQLENPHRIREVRRDIARIKTVLREKE 61
 
Name Accession Description Interval E-value
RpmC COG0255
Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 ...
3-62 3.47e-17

Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440025 [Multi-domain]  Cd Length: 65  Bit Score: 67.84  E-value: 3.47e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784287334  3 KAATLRTKDVAGLQAEIKDLQKAHFGLRMQKATQQLSNTSTLRVTRRDIARAKTILAQKQ 62
Cdd:COG0255    2 KAKELRELSDEELKEKLKELKKELFNLRFQHATGQLENPHRIREVRRDIARIKTVLREKE 61
Ribosomal_L29_HIP cd00427
Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called ...
7-61 3.03e-15

Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it participates in forming a protein ring that surrounds the polypeptide exit channel, providing structural support for the ribosome. L29 is involved in forming the translocon binding site, along with L19, L22, L23, L24, and L31e. In addition, L29 and L23 form the interaction site for trigger factor (TF) on the ribosomal surface, adjacent to the exit tunnel. L29 forms numerous interactions with L23 and with the 23S rRNA. In some eukaryotes, L29 is referred to as L35, which is distinct from L35 found in bacteria and some eukaryotes (primarily plastids and mitochondria). The mammalian homolog, HIP, is found on the surface of many tissues and cell lines. It is believed to play a role in cell adhesion and modulation of blood coagulation. It has also been shown to inhibit apoptosis in cancer cells.


Pssm-ID: 238243  Cd Length: 57  Bit Score: 62.51  E-value: 3.03e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1784287334  7 LRTKDVAGLQAEIKDLQKAHFGLRMQKATQQLSNTSTLRVTRRDIARAKTILAQK 61
Cdd:cd00427    3 LREKSDEELQEKLDELKKELFNLRFQKATGQLENPHRIRKVRKDIARIKTVLNEK 57
Ribosomal_L29 pfam00831
Ribosomal L29 protein;
7-60 5.45e-15

Ribosomal L29 protein;


Pssm-ID: 459954  Cd Length: 56  Bit Score: 62.03  E-value: 5.45e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 1784287334  7 LRTKDVAGLQAEIKDLQKAHFGLRMQKATQQLSNTSTLRVTRRDIARAKTILAQ 60
Cdd:pfam00831  3 LRELSDEELEEKLKELKKELFNLRFQKATGQLENPSRIREVRRDIARIKTVLRE 56
L29 TIGR00012
ribosomal protein L29; This model describes a ribosomal large subunit protein, called L29 in ...
7-60 3.41e-09

ribosomal protein L29; This model describes a ribosomal large subunit protein, called L29 in prokaryotic (50S) large subunits and L35 in eukaryotic (60S) large subunits. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 272854  Cd Length: 55  Bit Score: 47.23  E-value: 3.41e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 1784287334  7 LRTKDVAGLQAEIKDLQKAHFGLRMQKATQQLSNTSTLRVTRRDIARAKTILAQ 60
Cdd:TIGR00012  2 LREKSKEELAKKLDELKKELFELRFQKATGQLEKPHRIRQVRRDIARLLTVLRE 55
PRK14549 PRK14549
50S ribosomal protein L29P; Provisional
3-65 4.84e-04

50S ribosomal protein L29P; Provisional


Pssm-ID: 237751  Cd Length: 69  Bit Score: 34.58  E-value: 4.84e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1784287334  3 KAATLRTKDVAGLQAEIKDLQKAHFGLRMQKAT-QQLSNTSTLRVTRRDIARAKTILAQKQQET 65
Cdd:PRK14549   5 RASEIREMSPEEREEKLEELKLELLKERAQAAMgGAPENPGRIREIRRTIARILTIQREKKREA 68
 
Name Accession Description Interval E-value
RpmC COG0255
Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 ...
3-62 3.47e-17

Ribosomal protein L29 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L29 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 440025 [Multi-domain]  Cd Length: 65  Bit Score: 67.84  E-value: 3.47e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1784287334  3 KAATLRTKDVAGLQAEIKDLQKAHFGLRMQKATQQLSNTSTLRVTRRDIARAKTILAQKQ 62
Cdd:COG0255    2 KAKELRELSDEELKEKLKELKKELFNLRFQHATGQLENPHRIREVRRDIARIKTVLREKE 61
Ribosomal_L29_HIP cd00427
Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called ...
7-61 3.03e-15

Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it participates in forming a protein ring that surrounds the polypeptide exit channel, providing structural support for the ribosome. L29 is involved in forming the translocon binding site, along with L19, L22, L23, L24, and L31e. In addition, L29 and L23 form the interaction site for trigger factor (TF) on the ribosomal surface, adjacent to the exit tunnel. L29 forms numerous interactions with L23 and with the 23S rRNA. In some eukaryotes, L29 is referred to as L35, which is distinct from L35 found in bacteria and some eukaryotes (primarily plastids and mitochondria). The mammalian homolog, HIP, is found on the surface of many tissues and cell lines. It is believed to play a role in cell adhesion and modulation of blood coagulation. It has also been shown to inhibit apoptosis in cancer cells.


Pssm-ID: 238243  Cd Length: 57  Bit Score: 62.51  E-value: 3.03e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 1784287334  7 LRTKDVAGLQAEIKDLQKAHFGLRMQKATQQLSNTSTLRVTRRDIARAKTILAQK 61
Cdd:cd00427    3 LREKSDEELQEKLDELKKELFNLRFQKATGQLENPHRIRKVRKDIARIKTVLNEK 57
Ribosomal_L29 pfam00831
Ribosomal L29 protein;
7-60 5.45e-15

Ribosomal L29 protein;


Pssm-ID: 459954  Cd Length: 56  Bit Score: 62.03  E-value: 5.45e-15
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 1784287334  7 LRTKDVAGLQAEIKDLQKAHFGLRMQKATQQLSNTSTLRVTRRDIARAKTILAQ 60
Cdd:pfam00831  3 LRELSDEELEEKLKELKKELFNLRFQKATGQLENPSRIREVRRDIARIKTVLRE 56
L29 TIGR00012
ribosomal protein L29; This model describes a ribosomal large subunit protein, called L29 in ...
7-60 3.41e-09

ribosomal protein L29; This model describes a ribosomal large subunit protein, called L29 in prokaryotic (50S) large subunits and L35 in eukaryotic (60S) large subunits. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 272854  Cd Length: 55  Bit Score: 47.23  E-value: 3.41e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 1784287334  7 LRTKDVAGLQAEIKDLQKAHFGLRMQKATQQLSNTSTLRVTRRDIARAKTILAQ 60
Cdd:TIGR00012  2 LREKSKEELAKKLDELKKELFELRFQKATGQLEKPHRIRQVRRDIARLLTVLRE 55
PRK14549 PRK14549
50S ribosomal protein L29P; Provisional
3-65 4.84e-04

50S ribosomal protein L29P; Provisional


Pssm-ID: 237751  Cd Length: 69  Bit Score: 34.58  E-value: 4.84e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1784287334  3 KAATLRTKDVAGLQAEIKDLQKAHFGLRMQKAT-QQLSNTSTLRVTRRDIARAKTILAQKQQET 65
Cdd:PRK14549   5 RASEIREMSPEEREEKLEELKLELLKERAQAAMgGAPENPGRIREIRRTIARILTIQREKKREA 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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