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Conserved domains on  [gi|1797083315|gb|QHH84289|]
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protein-glutamate O-methyltransferase CheR [Bacillus paranthracis]

Protein Classification

CheR family methyltransferase( domain architecture ID 11442594)

CheR family methyltransferase is a class I SAM-dependent methyltransferase that catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor; such as chemotaxis protein methyltransferase that methylates membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0008168|GO:0032259|GO:1904047
PubMed:  9115443|12504684|23180741|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CheR COG1352
Methylase of chemotaxis methyl-accepting proteins [Signal transduction mechanisms];
1-260 1.10e-90

Methylase of chemotaxis methyl-accepting proteins [Signal transduction mechanisms];


:

Pssm-ID: 440963 [Multi-domain]  Cd Length: 272  Bit Score: 268.96  E-value: 1.10e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315   1 MIIEQDYDHFITSFKQQFNMDIASYKQDRMRRRIDAFISRKGFENYTTFLSTLRVDQNLFLSFIDYITINVSEFFRNKER 80
Cdd:COG1352     3 ELSDAEFERLLELLRERTGIDLSDYKRALLERRLERRMRALGLDSFSEYLELLRSDPEELQALIDALTINVTEFFRDPEH 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  81 WQTLESKALPKLLEQN--NGKLKVWSAACAAGEEPYTLSLILSKH---LSPFRYEILATDLDFHILESAKRGQYTERSLK 155
Cdd:COG1352    83 FEALREEVLPELLARRraGRPLRIWSAGCSTGEEPYSLAMLLAEAggeLAGWRVEILATDISEEALEKARAGIYPERSLR 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315 156 ELPSDLKERHFTKEDDIYSLHQNIKQHVTFKQHDLLM-QSFDTNYDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGGVLF 234
Cdd:COG1352   163 GLPPEYLSRYFTKEGGRYRIKPELREMVTFAQHNLLDdPPPFGRFDLIFCRNVLIYFDPELQRRVLRRFHDSLAPGGYLF 242

                         250       260
                  ....*....|....*....|....*...
gi 1797083315 235 VGSTEQIL-TPERFNLQRF-DTFFYEKI 260
Cdd:COG1352   243 LGHSESLGgLSDLFEPVDKkGRFIYRKR 270
 
Name Accession Description Interval E-value
CheR COG1352
Methylase of chemotaxis methyl-accepting proteins [Signal transduction mechanisms];
1-260 1.10e-90

Methylase of chemotaxis methyl-accepting proteins [Signal transduction mechanisms];


Pssm-ID: 440963 [Multi-domain]  Cd Length: 272  Bit Score: 268.96  E-value: 1.10e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315   1 MIIEQDYDHFITSFKQQFNMDIASYKQDRMRRRIDAFISRKGFENYTTFLSTLRVDQNLFLSFIDYITINVSEFFRNKER 80
Cdd:COG1352     3 ELSDAEFERLLELLRERTGIDLSDYKRALLERRLERRMRALGLDSFSEYLELLRSDPEELQALIDALTINVTEFFRDPEH 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  81 WQTLESKALPKLLEQN--NGKLKVWSAACAAGEEPYTLSLILSKH---LSPFRYEILATDLDFHILESAKRGQYTERSLK 155
Cdd:COG1352    83 FEALREEVLPELLARRraGRPLRIWSAGCSTGEEPYSLAMLLAEAggeLAGWRVEILATDISEEALEKARAGIYPERSLR 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315 156 ELPSDLKERHFTKEDDIYSLHQNIKQHVTFKQHDLLM-QSFDTNYDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGGVLF 234
Cdd:COG1352   163 GLPPEYLSRYFTKEGGRYRIKPELREMVTFAQHNLLDdPPPFGRFDLIFCRNVLIYFDPELQRRVLRRFHDSLAPGGYLF 242

                         250       260
                  ....*....|....*....|....*...
gi 1797083315 235 VGSTEQIL-TPERFNLQRF-DTFFYEKI 260
Cdd:COG1352   243 LGHSESLGgLSDLFEPVDKkGRFIYRKR 270
MeTrc smart00138
Methyltransferase, chemotaxis proteins; Methylates methyl-accepting chemotaxis proteins to ...
 4-257 2.05e-74

Methyltransferase, chemotaxis proteins; Methylates methyl-accepting chemotaxis proteins to form gamma-glutamyl methyl ester residues.


Pssm-ID: 214534 [Multi-domain]  Cd Length: 264  Bit Score: 227.55  E-value: 2.05e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315    4 EQDYDHFITSFKQQFNMDIASYKQDRMRRRIDAFISRKGFENYTTFLSTLRVDQNLFL--SFIDYITINVSEFFRNKERW 81
Cdd:smart00138   1 DADFRRFCVLIYSRTGIVLTDYKRTLLQSRLSRRLRVLGLKDFSEYLELLTSHRGEEElaELLDLMTTNETRFFRESKHF 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315   82 QTLESKALPKLLE--QNNGKLKVWSAACAAGEEPYTLSLILSKHL---SPFRYEILATDLDFHILESAKRGQYTERSLKE 156
Cdd:smart00138  81 EALEEKVLPLLIAsrRHGRRVRIWSAGCSTGEEPYSLAMLLAETLpkgREPDVKILATDIDLKALEKARAGIYPERELED 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  157 LPSDLKERHFTKEDDIYSLHQNIKQHVTFKQHDLLMQSF-DTNYDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGGVLFV 235
Cdd:smart00138 161 LPKALLARYFKEVEDKYRVKPELKERVRFAKHNLLAESPpLGDFDLIFCRNVLIYFDEPTQRKLLNRFAEALKPGGYLFL 240

                          250       260
                   ....*....|....*....|...
gi 1797083315  236 GSTEQILTPE-RFNLQRFDTFFY 257
Cdd:smart00138 241 GHSESLPGLTdKFEPIEGTVYFY 263
CheR pfam01739
CheR methyltransferase, SAM binding domain; CheR proteins are part of the chemotaxis signaling ...
 70-247 2.52e-61

CheR methyltransferase, SAM binding domain; CheR proteins are part of the chemotaxis signaling mechanism in bacteria. CheR methylates the chemotaxis receptor at specific glutamate residues. CheR is an S-adenosylmethionine- dependent methyltransferase - the C-terminal domain (this one) binds SAM.


Pssm-ID: 426403  Cd Length: 190  Bit Score: 191.34  E-value: 2.52e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  70 NVSEFFRNKERWQTLESKALPKLLEQNNGK-LKVWSAACAAGEEPYTLSLILSKHLS---PFRYEILATDLDFHILESAK 145
Cdd:pfam01739   1 NETRFFREPAHFEELKKYVLPLLAKAKNGKrVRIWSAGCSSGEEPYSLAMLLKETFPnaaRWDFKILATDIDLSVLEKAR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315 146 RGQYTERSLKELPSDLKERHFTK-EDDIYSLHQNIKQHVTFKQHDLL-MQSFDTNYDLIVCRNVMIYFTEEARVKLYEKF 223
Cdd:pfam01739  81 AGVYPERELEGLPEELLRRYFEKtAGGGYTVKPEIKSMVLFEYLNLLdEYPPLGDFDVIFCRNVLIYFDEETQRKILNRF 160

                         170       180
                  ....*....|....*....|....*
gi 1797083315 224 SRSLRKGGVLFVGSTEQILT-PERF 247
Cdd:pfam01739 161 AEKLKPGGYLFLGHSEALPGnPDKF 185
PRK10611 PRK10611
protein-glutamate O-methyltransferase CheR;
22-250 3.38e-32

protein-glutamate O-methyltransferase CheR;


Pssm-ID: 236725 [Multi-domain]  Cd Length: 287  Bit Score: 119.45  E-value: 3.38e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  22 IASYKQD----RMRRRIDAFisrkGFENYTTFLSTLRVDQNL--FLSFIDYITINVSEFFRnkerwqtlESKALPKLLE- 94
Cdd:PRK10611   42 LADHKREmvynRLVRRLRSL----GLNDFGQYLALLESNQNSaeWQAFINALTTNLTAFFR--------EAHHFPILAEh 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  95 --QNNGKLKVWSAACAAGEEPYTLSLILSKHL--SPFRYEILATDLDFHILESAKRGQYTERSLKELPSDLKERHFTKED 170
Cdd:PRK10611  110 arRRSGEYRVWSAAASTGEEPYSIAMTLADTLgtAPGRWKVFASDIDTEVLEKARSGIYRQEELKTLSPQQLQRYFMRGT 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315 171 DIYS----LHQNIKQHVTFKQHDLLMQ--SFDTNYDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGGVLFVGSTEQILTP 244
Cdd:PRK10611  190 GPHEglvrVRQELANYVDFQQLNLLAKqwAVPGPFDAIFCRNVMIYFDKTTQERILRRFVPLLKPDGLLFAGHSENFSQL 269


                  ....*..
gi 1797083315 245 ER-FNLQ 250
Cdd:PRK10611  270 SReFYLR 276
 
Name Accession Description Interval E-value
CheR COG1352
Methylase of chemotaxis methyl-accepting proteins [Signal transduction mechanisms];
1-260 1.10e-90

Methylase of chemotaxis methyl-accepting proteins [Signal transduction mechanisms];


Pssm-ID: 440963 [Multi-domain]  Cd Length: 272  Bit Score: 268.96  E-value: 1.10e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315   1 MIIEQDYDHFITSFKQQFNMDIASYKQDRMRRRIDAFISRKGFENYTTFLSTLRVDQNLFLSFIDYITINVSEFFRNKER 80
Cdd:COG1352     3 ELSDAEFERLLELLRERTGIDLSDYKRALLERRLERRMRALGLDSFSEYLELLRSDPEELQALIDALTINVTEFFRDPEH 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  81 WQTLESKALPKLLEQN--NGKLKVWSAACAAGEEPYTLSLILSKH---LSPFRYEILATDLDFHILESAKRGQYTERSLK 155
Cdd:COG1352    83 FEALREEVLPELLARRraGRPLRIWSAGCSTGEEPYSLAMLLAEAggeLAGWRVEILATDISEEALEKARAGIYPERSLR 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315 156 ELPSDLKERHFTKEDDIYSLHQNIKQHVTFKQHDLLM-QSFDTNYDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGGVLF 234
Cdd:COG1352   163 GLPPEYLSRYFTKEGGRYRIKPELREMVTFAQHNLLDdPPPFGRFDLIFCRNVLIYFDPELQRRVLRRFHDSLAPGGYLF 242

                         250       260
                  ....*....|....*....|....*...
gi 1797083315 235 VGSTEQIL-TPERFNLQRF-DTFFYEKI 260
Cdd:COG1352   243 LGHSESLGgLSDLFEPVDKkGRFIYRKR 270
MeTrc smart00138
Methyltransferase, chemotaxis proteins; Methylates methyl-accepting chemotaxis proteins to ...
 4-257 2.05e-74

Methyltransferase, chemotaxis proteins; Methylates methyl-accepting chemotaxis proteins to form gamma-glutamyl methyl ester residues.


Pssm-ID: 214534 [Multi-domain]  Cd Length: 264  Bit Score: 227.55  E-value: 2.05e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315    4 EQDYDHFITSFKQQFNMDIASYKQDRMRRRIDAFISRKGFENYTTFLSTLRVDQNLFL--SFIDYITINVSEFFRNKERW 81
Cdd:smart00138   1 DADFRRFCVLIYSRTGIVLTDYKRTLLQSRLSRRLRVLGLKDFSEYLELLTSHRGEEElaELLDLMTTNETRFFRESKHF 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315   82 QTLESKALPKLLE--QNNGKLKVWSAACAAGEEPYTLSLILSKHL---SPFRYEILATDLDFHILESAKRGQYTERSLKE 156
Cdd:smart00138  81 EALEEKVLPLLIAsrRHGRRVRIWSAGCSTGEEPYSLAMLLAETLpkgREPDVKILATDIDLKALEKARAGIYPERELED 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  157 LPSDLKERHFTKEDDIYSLHQNIKQHVTFKQHDLLMQSF-DTNYDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGGVLFV 235
Cdd:smart00138 161 LPKALLARYFKEVEDKYRVKPELKERVRFAKHNLLAESPpLGDFDLIFCRNVLIYFDEPTQRKLLNRFAEALKPGGYLFL 240

                          250       260
                   ....*....|....*....|...
gi 1797083315  236 GSTEQILTPE-RFNLQRFDTFFY 257
Cdd:smart00138 241 GHSESLPGLTdKFEPIEGTVYFY 263
CheR pfam01739
CheR methyltransferase, SAM binding domain; CheR proteins are part of the chemotaxis signaling ...
 70-247 2.52e-61

CheR methyltransferase, SAM binding domain; CheR proteins are part of the chemotaxis signaling mechanism in bacteria. CheR methylates the chemotaxis receptor at specific glutamate residues. CheR is an S-adenosylmethionine- dependent methyltransferase - the C-terminal domain (this one) binds SAM.


Pssm-ID: 426403  Cd Length: 190  Bit Score: 191.34  E-value: 2.52e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  70 NVSEFFRNKERWQTLESKALPKLLEQNNGK-LKVWSAACAAGEEPYTLSLILSKHLS---PFRYEILATDLDFHILESAK 145
Cdd:pfam01739   1 NETRFFREPAHFEELKKYVLPLLAKAKNGKrVRIWSAGCSSGEEPYSLAMLLKETFPnaaRWDFKILATDIDLSVLEKAR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315 146 RGQYTERSLKELPSDLKERHFTK-EDDIYSLHQNIKQHVTFKQHDLL-MQSFDTNYDLIVCRNVMIYFTEEARVKLYEKF 223
Cdd:pfam01739  81 AGVYPERELEGLPEELLRRYFEKtAGGGYTVKPEIKSMVLFEYLNLLdEYPPLGDFDVIFCRNVLIYFDEETQRKILNRF 160

                         170       180
                  ....*....|....*....|....*
gi 1797083315 224 SRSLRKGGVLFVGSTEQILT-PERF 247
Cdd:pfam01739 161 AEKLKPGGYLFLGHSEALPGnPDKF 185
PRK10611 PRK10611
protein-glutamate O-methyltransferase CheR;
22-250 3.38e-32

protein-glutamate O-methyltransferase CheR;


Pssm-ID: 236725 [Multi-domain]  Cd Length: 287  Bit Score: 119.45  E-value: 3.38e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  22 IASYKQD----RMRRRIDAFisrkGFENYTTFLSTLRVDQNL--FLSFIDYITINVSEFFRnkerwqtlESKALPKLLE- 94
Cdd:PRK10611   42 LADHKREmvynRLVRRLRSL----GLNDFGQYLALLESNQNSaeWQAFINALTTNLTAFFR--------EAHHFPILAEh 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315  95 --QNNGKLKVWSAACAAGEEPYTLSLILSKHL--SPFRYEILATDLDFHILESAKRGQYTERSLKELPSDLKERHFTKED 170
Cdd:PRK10611  110 arRRSGEYRVWSAAASTGEEPYSIAMTLADTLgtAPGRWKVFASDIDTEVLEKARSGIYRQEELKTLSPQQLQRYFMRGT 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1797083315 171 DIYS----LHQNIKQHVTFKQHDLLMQ--SFDTNYDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGGVLFVGSTEQILTP 244
Cdd:PRK10611  190 GPHEglvrVRQELANYVDFQQLNLLAKqwAVPGPFDAIFCRNVMIYFDKTTQERILRRFVPLLKPDGLLFAGHSENFSQL 269


                  ....*..
gi 1797083315 245 ER-FNLQ 250
Cdd:PRK10611  270 SReFYLR 276
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 182-231 7.59e-07

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 46.40  E-value: 7.59e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1797083315 182 HVTFKQHDLLMQSFDTN-YDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGG 231
Cdd:pfam13649  46 NVEFVQGDAEDLPFPDGsFDLVVSSGVLHHLPDPDLEAALREIARVLKPGG 96
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
182-235 1.80e-05

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 42.50  E-value: 1.80e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1797083315 182 HVTFKQHDLLMQSFDTNYDLIVCRNVMIYFTEeaRVKLYEKFSRSLRKGGVLFV 235
Cdd:COG4106    47 NVRFVVADLRDLDPPEPFDLVVSNAALHWLPD--HAALLARLAAALAPGGVLAV 98
CheR_N pfam03705
CheR methyltransferase, all-alpha domain; CheR proteins are part of the chemotaxis signaling ...
 5-57 3.90e-05

CheR methyltransferase, all-alpha domain; CheR proteins are part of the chemotaxis signaling mechanism in bacteria. CheR methylates the chemotaxis receptor at specific glutamate residues. CheR is an S-adenosylmethionine- dependent methyltransferase.


Pssm-ID: 461017 [Multi-domain]  Cd Length: 53  Bit Score: 40.11  E-value: 3.90e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1797083315   5 QDYDHFITSFKQQFNMDIASYKQDRMRRRIDAFISRKGFENYTTFLSTLRVDQ 57
Cdd:pfam03705   1 AEFERLLELIYRRTGIDLSDYKRSLLERRLSRRMRALGLDSFSEYLDLLRSDP 53
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 182-235 1.07e-04

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 42.21  E-value: 1.07e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1797083315 182 HVTFKQHDLLM--QSFDTNYDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGGVLFV 235
Cdd:COG0500    76 NVEFLVADLAEldPLPAESFDLVVAFGVLHHLPPEEREALLRELARALKPGGVLLL 131
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 182-235 7.65e-04

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 39.14  E-value: 7.65e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1797083315 182 HVTFKQHDLLMQSFDTNYDLIVCRNVMIYFTEEARVKLYEKFSRSLRKGGVLFV 235
Cdd:COG2230   102 RVEVRLADYRDLPADGQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLL 155
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 180-235 1.88e-03

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 37.30  E-value: 1.88e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1797083315 180 KQHVTFKQHDLL-MQSFDTNYDLIVCRNVMIYFTEEARVklYEKFSRSLRKGGVLFV 235
Cdd:COG2227    68 ELNVDFVQGDLEdLPLEDGSFDLVICSEVLEHLPDPAAL--LRELARLLKPGGLLLL 122
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 182-252 6.86e-03

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 36.13  E-value: 6.86e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1797083315 182 HVTFKQHDLLMQSFDTN-YDLIVCRNVMIYFTEEARVklYEKFSRSLRKGGVLFVGsteQILTPERFNLQRF 252
Cdd:COG2226    70 NVEFVVGDAEDLPFPDGsFDLVISSFVLHHLPDPERA--LAEIARVLKPGGRLVVV---DFSPPDLAELEEL 136
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
182-239 8.70e-03

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 36.13  E-value: 8.70e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1797083315 182 HVTFKQHDLL-MQSFDTNYDLIVCRNVMIYFteEARVKLYEKFSRSLRKGGvLFVGSTE 239
Cdd:COG4976    90 YDRLLVADLAdLAEPDGRFDLIVAADVLTYL--GDLAAVFAGVARALKPGG-LFIFSVE 145
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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