|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15069 |
PRK15069 |
histidine ABC transporter permease HisM; |
1-234 |
6.07e-162 |
|
histidine ABC transporter permease HisM;
Pssm-ID: 185029 [Multi-domain] Cd Length: 234 Bit Score: 447.19 E-value: 6.07e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 1 MIDIIQEYWKSLLWTDGYRFTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYS 80
Cdd:PRK15069 1 MIEILQEYWKALLWTDGYRFTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 81 GMYTLEIVKGTELLNAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIAL 160
Cdd:PRK15069 81 GMYSLEIVRGTDLLDAFFRSGLNCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRAL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1878644999 161 PAYSNEVILMLHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRWLQHIKP 234
Cdd:PRK15069 161 PAYSNEVILMLHATTLAFTATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERRWLAHLKP 234
|
|
| ArtM |
COG4160 |
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ... |
2-236 |
1.08e-106 |
|
ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 443325 [Multi-domain] Cd Length: 229 Bit Score: 307.02 E-value: 1.08e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 2 IDIIQEYWKSLLwtdgyrfTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSG 81
Cdd:COG4160 3 LDLLFEYLPLLL-------SGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 82 MYTLEIVKGTeLLNAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALP 161
Cdd:COG4160 76 LGQFEWVRES-WLWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALP 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1878644999 162 AYSNEVILMLHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRWLQHIKPSS 236
Cdd:COG4160 155 AYSNEVILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLRHLRPRR 229
|
|
| TM_PBP2 |
cd06261 |
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ... |
25-218 |
5.00e-15 |
|
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.
Pssm-ID: 119394 [Multi-domain] Cd Length: 190 Bit Score: 70.77 E-value: 5.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 25 ITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSGMytleivkGTELLNAFFRSGLNC 104
Cdd:cd06261 3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLF-------GVLLGWGILPGLGLP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 105 TVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALPAYSNEVILMLHSTALAFTATVPD 184
Cdd:cd06261 76 ALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE 155
|
170 180 190
....*....|....*....|....*....|....
gi 1878644999 185 LLKIARDINSATYQPFTAFGIAAVLYLIISYVLI 218
Cdd:cd06261 156 APGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
|
|
| HEQRo_perm_3TM |
TIGR01726 |
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ... |
20-123 |
7.03e-12 |
|
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130787 [Multi-domain] Cd Length: 99 Bit Score: 59.85 E-value: 7.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 20 FTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLeivkGTELlnaffr 99
Cdd:TIGR01726 6 LKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLI----GIRL------ 75
|
90 100
....*....|....*....|....
gi 1878644999 100 SGLNCTVLALTLNTCAYTTEIFAG 123
Cdd:TIGR01726 76 SPLTAAVIALTLFYGAYLAEIFRG 99
|
|
| BPD_transp_1 |
pfam00528 |
Binding-protein-dependent transport system inner membrane component; The alignments cover the ... |
37-227 |
4.93e-06 |
|
Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.
Pssm-ID: 334128 [Multi-domain] Cd Length: 183 Bit Score: 45.75 E-value: 4.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 37 GGILAVFLAIGRvssNKFIQFPIWLFTYIFRGTPLYVQLLVFYsgmytleivkgTELLNAFFRSGLNCTVLALTLNTCAY 116
Cdd:pfam00528 1 GIPLGIIAALRR---GRRLDRLLRPLIDLLQALPSFVLAILLV-----------VIAILSILGHGILPAIILALLGWAGY 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 117 TTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALPAYSNEVI-LMLHSTALAFTATVPDL--LKIARDIN 193
Cdd:pfam00528 67 ARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGgALGGAVLLEFLGSWPGLglLLIEAILG 146
|
170 180 190
....*....|....*....|....*....|....
gi 1878644999 194 SATYQPFTAFGIAAVLYLIISYVLISLFRRAEKR 227
Cdd:pfam00528 147 YDYPEIQGPVLAAALILLLLNLLVDILQRLLDPR 180
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15069 |
PRK15069 |
histidine ABC transporter permease HisM; |
1-234 |
6.07e-162 |
|
histidine ABC transporter permease HisM;
Pssm-ID: 185029 [Multi-domain] Cd Length: 234 Bit Score: 447.19 E-value: 6.07e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 1 MIDIIQEYWKSLLWTDGYRFTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYS 80
Cdd:PRK15069 1 MIEILQEYWKALLWTDGYRFTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 81 GMYTLEIVKGTELLNAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIAL 160
Cdd:PRK15069 81 GMYSLEIVRGTDLLDAFFRSGLNCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRAL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1878644999 161 PAYSNEVILMLHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRWLQHIKP 234
Cdd:PRK15069 161 PAYSNEVILMLHATTLAFTATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERRWLAHLKP 234
|
|
| ArtM |
COG4160 |
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ... |
2-236 |
1.08e-106 |
|
ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 443325 [Multi-domain] Cd Length: 229 Bit Score: 307.02 E-value: 1.08e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 2 IDIIQEYWKSLLwtdgyrfTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSG 81
Cdd:COG4160 3 LDLLFEYLPLLL-------SGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 82 MYTLEIVKGTeLLNAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALP 161
Cdd:COG4160 76 LGQFEWVRES-WLWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALP 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1878644999 162 AYSNEVILMLHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRWLQHIKPSS 236
Cdd:COG4160 155 AYSNEVILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLRHLRPRR 229
|
|
| HisM |
COG0765 |
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ... |
2-228 |
3.80e-62 |
|
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440528 [Multi-domain] Cd Length: 218 Bit Score: 193.75 E-value: 3.80e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 2 IDIIQEYWKSLLwtdgyrfTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSG 81
Cdd:COG0765 5 FSVLLDYLPLLL-------EGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 82 MYTLEIVkgtelLNAFFRSglnctVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALP 161
Cdd:COG0765 78 LPLLGID-----LSPFVAA-----VIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILP 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1878644999 162 AYSNEVILMLHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRW 228
Cdd:COG0765 148 PLGNEFISLLKDTSLVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRL 214
|
|
| artM |
PRK11122 |
arginine ABC transporter permease ArtM; |
22-229 |
1.30e-41 |
|
arginine ABC transporter permease ArtM;
Pssm-ID: 182978 [Multi-domain] Cd Length: 222 Bit Score: 141.25 E-value: 1.30e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 22 GVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTELLNAFFRSG 101
Cdd:PRK11122 11 GLHTSLTLTVASLLVALVLALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPWLQEYPWLWHLLSQP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 102 LNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRcIILPSALRIALPAYSNEVILMLHSTALAFTAT 181
Cdd:PRK11122 91 WLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTLR-ILLPYAFKRALSSYSNEVVLVFKSTSLAYTIT 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1878644999 182 VPDLLKIARDINSATYQpFTAFGIAAVLYLIISYVLISLFRRAEKRWL 229
Cdd:PRK11122 170 LMDVMGYSQLLYGRTYD-VMVFGAAGIIYLVVNGLLTLLMRLIERKAL 216
|
|
| PRK15100 |
PRK15100 |
cystine ABC transporter permease; |
22-231 |
5.09e-31 |
|
cystine ABC transporter permease;
Pssm-ID: 185055 [Multi-domain] Cd Length: 220 Bit Score: 113.69 E-value: 5.09e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 22 GVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLeivkGTELlnaffrSG 101
Cdd:PRK15100 18 GAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQF----GIEL------DP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 102 LNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALPAYSNEVILMLHSTALAFTAT 181
Cdd:PRK15100 88 IPAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATIQ 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1878644999 182 VPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRWLQH 231
Cdd:PRK15100 168 VPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSALQNRFENQLNRQ 217
|
|
| PRK11123 |
PRK11123 |
arginine ABC transporter permease ArtQ; |
25-227 |
4.19e-30 |
|
arginine ABC transporter permease ArtQ;
Pssm-ID: 182979 [Multi-domain] Cd Length: 238 Bit Score: 112.08 E-value: 4.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 25 ITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTP-----LYV-----QLLVFYSGMYTLEIVKGTELL 94
Cdd:PRK11123 13 MTVGLAVCALIVGLALAMLFAVWESAKWRPVAWPGTALVTLLRGLPeilvvLFIyfgssQLLLTLSDGFTLNLGFVQIPV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 95 ----NAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALPAYSNEVILM 170
Cdd:PRK11123 93 qmdiENFEVSPFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQWLVL 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1878644999 171 LHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKR 227
Cdd:PRK11123 173 LKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIIAAAIYLVITLISQYILKRIELR 229
|
|
| PRK15135 |
PRK15135 |
histidine ABC transporter permease HisQ; |
20-233 |
1.37e-24 |
|
histidine ABC transporter permease HisQ;
Pssm-ID: 185089 [Multi-domain] Cd Length: 228 Bit Score: 97.17 E-value: 1.37e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 20 FTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTP-LYVQLLVFYSGMYTLEIVKGTELLNAFF 98
Cdd:PRK15135 10 LQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPdLVLMLLIFYGLQIALNSVTEALGVGQID 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 99 RSGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALPAYSNEVILMLHSTALAF 178
Cdd:PRK15135 90 IDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQVILKATALVS 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1878644999 179 TATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRWLQHIK 233
Cdd:PRK15135 170 LLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLWLERRYSVGVK 224
|
|
| glnP |
PRK09494 |
glutamine ABC transporter permease protein; Reviewed |
20-227 |
3.43e-19 |
|
glutamine ABC transporter permease protein; Reviewed
Pssm-ID: 181907 [Multi-domain] Cd Length: 219 Bit Score: 82.80 E-value: 3.43e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 20 FTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYsgmYTLEIvkgteLLNAFFR 99
Cdd:PRK09494 16 LEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQVMFIY---FALPM-----AFNDLRI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 100 SGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALPAYSNEVILMLHSTALAFT 179
Cdd:PRK09494 88 DPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLGNQWIISIKDTSLFIV 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1878644999 180 ATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKR 227
Cdd:PRK09494 168 IGVAELTRQGQEIIAGNFRALEIWSAVAVIYLIITLVLSFILRRLERR 215
|
|
| TM_PBP2 |
cd06261 |
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ... |
25-218 |
5.00e-15 |
|
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.
Pssm-ID: 119394 [Multi-domain] Cd Length: 190 Bit Score: 70.77 E-value: 5.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 25 ITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSGMytleivkGTELLNAFFRSGLNC 104
Cdd:cd06261 3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLF-------GVLLGWGILPGLGLP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 105 TVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALPAYSNEVILMLHSTALAFTATVPD 184
Cdd:cd06261 76 ALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGE 155
|
170 180 190
....*....|....*....|....*....|....
gi 1878644999 185 LLKIARDINSATYQPFTAFGIAAVLYLIISYVLI 218
Cdd:cd06261 156 APGPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
|
|
| PRK15107 |
PRK15107 |
glutamate/aspartate ABC transporter permease GltK; |
9-227 |
2.83e-12 |
|
glutamate/aspartate ABC transporter permease GltK;
Pssm-ID: 185062 [Multi-domain] Cd Length: 224 Bit Score: 64.08 E-value: 2.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 9 WKSLLWTDGYRFTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYsgMYTLEIV 88
Cdd:PRK15107 6 WSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIPLVMVLLWFY--LIVPGFL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 89 KGTELLNAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALPAYSNEVI 168
Cdd:PRK15107 84 QNVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGI 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1878644999 169 LMLHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLIISYVLISLFRRAEKR 227
Cdd:PRK15107 164 VLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKKR 222
|
|
| HEQRo_perm_3TM |
TIGR01726 |
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ... |
20-123 |
7.03e-12 |
|
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130787 [Multi-domain] Cd Length: 99 Bit Score: 59.85 E-value: 7.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 20 FTGVAITLWLLISSVVMGGILAVFLAIGRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLeivkGTELlnaffr 99
Cdd:TIGR01726 6 LKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLI----GIRL------ 75
|
90 100
....*....|....*....|....
gi 1878644999 100 SGLNCTVLALTLNTCAYTTEIFAG 123
Cdd:TIGR01726 76 SPLTAAVIALTLFYGAYLAEIFRG 99
|
|
| BPD_transp_1 |
pfam00528 |
Binding-protein-dependent transport system inner membrane component; The alignments cover the ... |
37-227 |
4.93e-06 |
|
Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.
Pssm-ID: 334128 [Multi-domain] Cd Length: 183 Bit Score: 45.75 E-value: 4.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 37 GGILAVFLAIGRvssNKFIQFPIWLFTYIFRGTPLYVQLLVFYsgmytleivkgTELLNAFFRSGLNCTVLALTLNTCAY 116
Cdd:pfam00528 1 GIPLGIIAALRR---GRRLDRLLRPLIDLLQALPSFVLAILLV-----------VIAILSILGHGILPAIILALLGWAGY 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 117 TTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSALRIALPAYSNEVI-LMLHSTALAFTATVPDL--LKIARDIN 193
Cdd:pfam00528 67 ARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGgALGGAVLLEFLGSWPGLglLLIEAILG 146
|
170 180 190
....*....|....*....|....*....|....
gi 1878644999 194 SATYQPFTAFGIAAVLYLIISYVLISLFRRAEKR 227
Cdd:pfam00528 147 YDYPEIQGPVLAAALILLLLNLLVDILQRLLDPR 180
|
|
| PhnE |
TIGR01097 |
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ... |
20-156 |
2.83e-03 |
|
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]
Pssm-ID: 273441 [Multi-domain] Cd Length: 250 Bit Score: 37.91 E-value: 2.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 20 FTGVAITLWLLISSVVMGGILAVFLAI---GRVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYsgmytleivkgtellnA 96
Cdd:TIGR01097 57 LKALLETLAMAILGTVLAAVLAVPLALlaaRNITPSPWLYGLARLLLNFLRAIPELVWALIFV----------------A 120
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 97 FFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSAL 156
Cdd:TIGR01097 121 AVGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVL 180
|
|
| TauC |
COG0600 |
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ... |
3-156 |
7.01e-03 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440365 [Multi-domain] Cd Length: 254 Bit Score: 36.66 E-value: 7.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1878644999 3 DIIQEYWKslLWTDGYRFTGVAITLWLLISSVVMGGILAVFLAIGrVSSNKFIQFPIWLFTYIFRGTPLYVQLLVFYsgm 82
Cdd:COG0600 45 AVLAALVE--LLASGELWEHLLASLLRVLLGFALAALLGVPLGLL-LGLSRLLRRLLDPLLVFLRPIPPLALAPLLI--- 118
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1878644999 83 ytleivkgtellnAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPAGEIEAARAYGFSSVKMYRCIILPSAL 156
Cdd:COG0600 119 -------------LWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAAL 179
|
|
| PTZ00370 |
PTZ00370 |
STEVOR; Provisional |
170-228 |
8.96e-03 |
|
STEVOR; Provisional
Pssm-ID: 240386 Cd Length: 296 Bit Score: 36.55 E-value: 8.96e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1878644999 170 MLHSTALAFTATVPDLLKIARDINSATYQPFtafGIAAVLYLIISYVLISLF----RRAEKRW 228
Cdd:PTZ00370 227 IISALKAGGVTCVSGLAGTAASAASSAFYPY---GIAALVLLILAVVLIILYiwlyRRRKNSW 286
|
|
| |
