|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
1-548 |
0e+00 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 753.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 1 MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQaqqttqttttaagsaadqgvPASGQGKLITVKTDVLDLTINTRGGDVE 80
Cdd:PRK01318 1 MDNKRLLLAIALSFVIFLGWQYWQQDKAQAAA--------------------QAPAPQARITVETDVLRLSIDTKGGRID 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 81 QASLPAYPKELGSTEPFQLLETTPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQNELQIPMTYTDAAGNT 160
Cdd:PRK01318 61 DLLLKKYKETLDSSPPVVLLSPSTEHPYFAQSGLTGADGPDNVPNPDRTLYTADGDSLVLADGQNELPVTLTWTNGNGLT 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 161 FTKTFVLKRGEYAVNVNYSVQNAGEKPLEVSTFGQLKQsinlpshrdTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAE 240
Cdd:PRK01318 141 FTKTYTLDRGDYMFTVEYSVNNNSGAPVNLSPYGQLKR---------TGSSNFASYTFHGGAIGTPDEKYEKYTYKDIDD 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 241 NENlnVNAKDGWVAMLQQYFATAWVPrNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMTSTLWVGPEIQDKMA-A 319
Cdd:PRK01318 212 NLN--ISSKGGWVAILDKYFATALIP-QNGQNNFYSKNLGNGLYQVGFKSPPVTVAPGQSASTTARLYAGPKEVKLLAkE 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 320 VAPHLDLTVDYGWLWFISQPLFKLLKWIHSFLGNWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGD 399
Cdd:PRK01318 289 IAPGLDLAVDYGWLWFITKPLFWLLDFLHSFVGNWGWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKYKD 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 400 DKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFALWIHDLSAQDPYYIL-----PILMGVT 474
Cdd:PRK01318 369 DPQKMQQEMMELYKKEKVNPLGGCLPILIQIPIFFALYKVLLVSIELRHAPFIGWIHDLSAPDPYFILhigllPILMGIT 448
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1880759852 475 MFFIQKMSPTTvTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKNS 548
Cdd:PRK01318 449 MFLQQKLNPTP-TDPMQAKIMKFMPLIFTFFFLSFPAGLVLYWIVNNLLTIIQQYLINRRLEKKKLLAANKKKK 521
|
|
| yidC_nterm |
TIGR03593 |
membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Essentially all bacteria have ... |
3-352 |
1.04e-127 |
|
membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Essentially all bacteria have a member of the YidC family, whose C-terminal domain is modeled by TIGR03592. The two copies are found in endospore-forming bacteria such as Bacillus subtilis appear redundant during vegetative growth, although the member designated spoIIIJ (stage III sporulation protein J) has a distinct role in spore formation. YidC, its mitochondrial homolog Oxa1, and its chloroplast homolog direct insertion into the bacterial/organellar inner (or only) membrane. This model describes an N-terminal sequence region, including a large periplasmic domain lacking in YidC members from Gram-positive species. The multifunctional YidC protein acts both with and independently of the Sec system. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274666 Cd Length: 366 Bit Score: 377.83 E-value: 1.04e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 3 SQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPA-----------------SGQGKLITVKT 65
Cdd:TIGR03593 1 NRRLILAIALSFVIFLLWQAWQSDPGPPPPKPPAAAQEASAASATAAATSAAapaaadapsaaaaadaaAATAKRITVET 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 66 DVLDLTINTRGGDVEQASLPAYPKELGSTE-PFQLLETTPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQ 144
Cdd:TIGR03593 81 DVLRASISTKGGDIDSLELKKYKETLDKDSpPVLLLSDGAERLYVAQSGLIGANGADLALPGHRTVWQAEGGEYTLTPGQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 145 neLQIPMTYTDAAGNTFTKTFVLKRGEYAVNVNYSVQNAGEKPLEVSTFGQLKQSINLPshrdTGSSNFALHTFRGAAYS 224
Cdd:TIGR03593 161 --LPVTLTWDNSNGVTVTKTYTFDRDSYLIDVEYKVTNNGDAPVSLSLYGQLKRDLSPT----EKSTYFLHETFTGAAYY 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 225 TPDEKYEKYKFDTIAENeNLNV--NAKDGWVAMLQQYFATAWVPRN--DGTNNFYTAN-LGNGIAAIGYKSQPVLVQPGQ 299
Cdd:TIGR03593 235 TDGEKYQKVSFKDIEKK-KLNVetKGGAGWVGMLQHYFASAWIPPAgsDGTTAFYYGRkLGNNVYIAGFVSPVVTVAPGQ 313
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1880759852 300 TGAMTSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFLG 352
Cdd:TIGR03593 314 SATIKSRLYAGPKEQDVLKAIAPGLDLAVDYGWLWFIAKPLFWLLDFFHSLVG 366
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
328-539 |
3.99e-122 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 357.51 E-value: 3.99e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 328 VDYGWLWFISQPLFKLLKWIHSFLGNWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQE 407
Cdd:COG0706 1 IDYGWFGFIAKPLFWLLNFLHSLVGNWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKDDPQKLQQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 408 MMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFaLWIHDLSAQDPYYI-LPILMGVTMFFIQKMSPTTV 486
Cdd:COG0706 81 MMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPF-LGIPDLSAPDPYYIfLPILMGVTMFLQQKLNPAPA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1880759852 487 TDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRG 539
Cdd:COG0706 160 QDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDKKK 212
|
|
| YidC_periplas |
pfam14849 |
YidC periplasmic domain; This is the periplasmic domain of YidC, a bacterial membrane protein ... |
61-330 |
2.02e-105 |
|
YidC periplasmic domain; This is the periplasmic domain of YidC, a bacterial membrane protein which is required for the insertion and assembly of inner membrane proteins.
Pssm-ID: 464346 Cd Length: 266 Bit Score: 316.91 E-value: 2.02e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 61 ITVKTDVLDLTINTRGGDVEQASLPAYPKELGS-TEPFQLLETTPQFIYQAQSGLTGRDGPDNPAngPRPLYNVEKDAFV 139
Cdd:pfam14849 1 ITVETDVLRGSISLKGGRIDDLELKKYRETLDDdSPPVVLLSPSGGRTYVAQSGLIGAGGPDLPP--HDTVFTAEGGSYT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 140 LADGQNELQIPMTYTDAAGNTFTKTFVLKRGEYAVNVNYSVQNAGEKPLEVSTFGQLKQSinlpSHRDTGSSNFALHTfr 219
Cdd:pfam14849 79 LADGTDELPVTLTWDNGNGVTFTKTYTFDRGSYLIDVTYEVENTSGAPVTLQPYGQLVRD----PGEPEGSSFYITYT-- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 220 GAAYSTPDEKYEKYKFDTIAENENLNVN--AKDGWVAMLQQYFATAWVPRNDGT-NNFYTANLGNGIAAIGYKSQPVLVQ 296
Cdd:pfam14849 153 GAAGSTDEGKYQKVSFDDIEKGGKLKVDttTGGGWVAMTQHYFLSAWIPDQDGTtNEFYTRFLGGNLYQAGYISPAVTVA 232
|
250 260 270
....*....|....*....|....*....|....
gi 1880759852 297 PGQTGAMTSTLWVGPEIQDKMAAVAPHLDLTVDY 330
Cdd:pfam14849 233 PGASATVTARLFAGPKEQKVLEAIAPGLDLAVDY 266
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
355-533 |
9.42e-99 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 296.60 E-value: 9.42e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 355 GFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFL 434
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDDKQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 435 ALYYMLMGSIELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVT--DPMQQKIMTFMPVIFTVFFLWFPSG 512
Cdd:cd20070 81 ALYQVLRNSIELRGAPFLWWILDLSAPDPYYILPILMGVTMFLQQKLTPTPTDdqAPQQKMMMYFMPVMFTFIFLSFPSG 160
|
170 180
....*....|....*....|.
gi 1880759852 513 LVLYYIVSNLVTIIQQQLIYR 533
Cdd:cd20070 161 LVLYWLVSNLFSIIQQLIINK 181
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
1-548 |
0e+00 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 753.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 1 MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQaqqttqttttaagsaadqgvPASGQGKLITVKTDVLDLTINTRGGDVE 80
Cdd:PRK01318 1 MDNKRLLLAIALSFVIFLGWQYWQQDKAQAAA--------------------QAPAPQARITVETDVLRLSIDTKGGRID 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 81 QASLPAYPKELGSTEPFQLLETTPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQNELQIPMTYTDAAGNT 160
Cdd:PRK01318 61 DLLLKKYKETLDSSPPVVLLSPSTEHPYFAQSGLTGADGPDNVPNPDRTLYTADGDSLVLADGQNELPVTLTWTNGNGLT 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 161 FTKTFVLKRGEYAVNVNYSVQNAGEKPLEVSTFGQLKQsinlpshrdTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAE 240
Cdd:PRK01318 141 FTKTYTLDRGDYMFTVEYSVNNNSGAPVNLSPYGQLKR---------TGSSNFASYTFHGGAIGTPDEKYEKYTYKDIDD 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 241 NENlnVNAKDGWVAMLQQYFATAWVPrNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMTSTLWVGPEIQDKMA-A 319
Cdd:PRK01318 212 NLN--ISSKGGWVAILDKYFATALIP-QNGQNNFYSKNLGNGLYQVGFKSPPVTVAPGQSASTTARLYAGPKEVKLLAkE 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 320 VAPHLDLTVDYGWLWFISQPLFKLLKWIHSFLGNWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGD 399
Cdd:PRK01318 289 IAPGLDLAVDYGWLWFITKPLFWLLDFLHSFVGNWGWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKYKD 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 400 DKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFALWIHDLSAQDPYYIL-----PILMGVT 474
Cdd:PRK01318 369 DPQKMQQEMMELYKKEKVNPLGGCLPILIQIPIFFALYKVLLVSIELRHAPFIGWIHDLSAPDPYFILhigllPILMGIT 448
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1880759852 475 MFFIQKMSPTTvTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKNS 548
Cdd:PRK01318 449 MFLQQKLNPTP-TDPMQAKIMKFMPLIFTFFFLSFPAGLVLYWIVNNLLTIIQQYLINRRLEKKKLLAANKKKK 521
|
|
| yidC_nterm |
TIGR03593 |
membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Essentially all bacteria have ... |
3-352 |
1.04e-127 |
|
membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Essentially all bacteria have a member of the YidC family, whose C-terminal domain is modeled by TIGR03592. The two copies are found in endospore-forming bacteria such as Bacillus subtilis appear redundant during vegetative growth, although the member designated spoIIIJ (stage III sporulation protein J) has a distinct role in spore formation. YidC, its mitochondrial homolog Oxa1, and its chloroplast homolog direct insertion into the bacterial/organellar inner (or only) membrane. This model describes an N-terminal sequence region, including a large periplasmic domain lacking in YidC members from Gram-positive species. The multifunctional YidC protein acts both with and independently of the Sec system. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274666 Cd Length: 366 Bit Score: 377.83 E-value: 1.04e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 3 SQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPA-----------------SGQGKLITVKT 65
Cdd:TIGR03593 1 NRRLILAIALSFVIFLLWQAWQSDPGPPPPKPPAAAQEASAASATAAATSAAapaaadapsaaaaadaaAATAKRITVET 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 66 DVLDLTINTRGGDVEQASLPAYPKELGSTE-PFQLLETTPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQ 144
Cdd:TIGR03593 81 DVLRASISTKGGDIDSLELKKYKETLDKDSpPVLLLSDGAERLYVAQSGLIGANGADLALPGHRTVWQAEGGEYTLTPGQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 145 neLQIPMTYTDAAGNTFTKTFVLKRGEYAVNVNYSVQNAGEKPLEVSTFGQLKQSINLPshrdTGSSNFALHTFRGAAYS 224
Cdd:TIGR03593 161 --LPVTLTWDNSNGVTVTKTYTFDRDSYLIDVEYKVTNNGDAPVSLSLYGQLKRDLSPT----EKSTYFLHETFTGAAYY 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 225 TPDEKYEKYKFDTIAENeNLNV--NAKDGWVAMLQQYFATAWVPRN--DGTNNFYTAN-LGNGIAAIGYKSQPVLVQPGQ 299
Cdd:TIGR03593 235 TDGEKYQKVSFKDIEKK-KLNVetKGGAGWVGMLQHYFASAWIPPAgsDGTTAFYYGRkLGNNVYIAGFVSPVVTVAPGQ 313
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1880759852 300 TGAMTSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFLG 352
Cdd:TIGR03593 314 SATIKSRLYAGPKEQDVLKAIAPGLDLAVDYGWLWFIAKPLFWLLDFFHSLVG 366
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
328-539 |
3.99e-122 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 357.51 E-value: 3.99e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 328 VDYGWLWFISQPLFKLLKWIHSFLGNWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQE 407
Cdd:COG0706 1 IDYGWFGFIAKPLFWLLNFLHSLVGNWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKDDPQKLQQE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 408 MMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFaLWIHDLSAQDPYYI-LPILMGVTMFFIQKMSPTTV 486
Cdd:COG0706 81 MMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPF-LGIPDLSAPDPYYIfLPILMGVTMFLQQKLNPAPA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1880759852 487 TDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRG 539
Cdd:COG0706 160 QDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDKKK 212
|
|
| YidC_periplas |
pfam14849 |
YidC periplasmic domain; This is the periplasmic domain of YidC, a bacterial membrane protein ... |
61-330 |
2.02e-105 |
|
YidC periplasmic domain; This is the periplasmic domain of YidC, a bacterial membrane protein which is required for the insertion and assembly of inner membrane proteins.
Pssm-ID: 464346 Cd Length: 266 Bit Score: 316.91 E-value: 2.02e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 61 ITVKTDVLDLTINTRGGDVEQASLPAYPKELGS-TEPFQLLETTPQFIYQAQSGLTGRDGPDNPAngPRPLYNVEKDAFV 139
Cdd:pfam14849 1 ITVETDVLRGSISLKGGRIDDLELKKYRETLDDdSPPVVLLSPSGGRTYVAQSGLIGAGGPDLPP--HDTVFTAEGGSYT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 140 LADGQNELQIPMTYTDAAGNTFTKTFVLKRGEYAVNVNYSVQNAGEKPLEVSTFGQLKQSinlpSHRDTGSSNFALHTfr 219
Cdd:pfam14849 79 LADGTDELPVTLTWDNGNGVTFTKTYTFDRGSYLIDVTYEVENTSGAPVTLQPYGQLVRD----PGEPEGSSFYITYT-- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 220 GAAYSTPDEKYEKYKFDTIAENENLNVN--AKDGWVAMLQQYFATAWVPRNDGT-NNFYTANLGNGIAAIGYKSQPVLVQ 296
Cdd:pfam14849 153 GAAGSTDEGKYQKVSFDDIEKGGKLKVDttTGGGWVAMTQHYFLSAWIPDQDGTtNEFYTRFLGGNLYQAGYISPAVTVA 232
|
250 260 270
....*....|....*....|....*....|....
gi 1880759852 297 PGQTGAMTSTLWVGPEIQDKMAAVAPHLDLTVDY 330
Cdd:pfam14849 233 PGASATVTARLFAGPKEQKVLEAIAPGLDLAVDY 266
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
353-531 |
1.81e-102 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 305.95 E-value: 1.81e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 353 NWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPI 432
Cdd:TIGR03592 1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKEDPQKLQQEMMKLYKEEGVNPLGGCLPLLIQMPI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 433 FLALYYMLMGSIELRHAPFaLWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMT-FMPVIFTVFFLWFPS 511
Cdd:TIGR03592 81 FIALYQVLLRSIELRHAPF-LWIIDLSSPDPYYILPILMGVTMFLQQKLSPKGPPDPAQQKMMMyFMPLMFLFFFLSFPA 159
|
170 180
....*....|....*....|
gi 1880759852 512 GLVLYYIVSNLVTIIQQQLI 531
Cdd:TIGR03592 160 GLVLYWVVSNLFTIIQQLII 179
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
354-533 |
8.95e-100 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 299.39 E-value: 8.95e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 354 WGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIF 433
Cdd:pfam02096 1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQKLQQEMMKLYKKEGVNPLGGCLPMLIQMPIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 434 LALYYMLMGSIELRHAPFALWIHDLSAQDP-----YYILPILMGVTMFFIQKMSPTTVTDPMQQKIMT--FMPVIFTVFF 506
Cdd:pfam02096 81 IALYRVLRNSIELRHAPFFLWIADLSAPDPisilhYYILPILMGVTMFLQQKLTPAPQDQPPQMKMMMlyFMPLMFLFFF 160
|
170 180
....*....|....*....|....*..
gi 1880759852 507 LWFPSGLVLYYIVSNLVTIIQQQLIYR 533
Cdd:pfam02096 161 LNFPAGLVLYWVVSNLLSIGQQLIINR 187
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
355-533 |
9.42e-99 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 296.60 E-value: 9.42e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 355 GFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFL 434
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDDKQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 435 ALYYMLMGSIELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVT--DPMQQKIMTFMPVIFTVFFLWFPSG 512
Cdd:cd20070 81 ALYQVLRNSIELRGAPFLWWILDLSAPDPYYILPILMGVTMFLQQKLTPTPTDdqAPQQKMMMYFMPVMFTFIFLSFPSG 160
|
170 180
....*....|....*....|.
gi 1880759852 513 LVLYYIVSNLVTIIQQQLIYR 533
Cdd:cd20070 161 LVLYWLVSNLFSIIQQLIINK 181
|
|
| 5TM_YidC_Oxa1_Alb3 |
cd19751 |
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ... |
355-533 |
7.44e-88 |
|
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410992 [Multi-domain] Cd Length: 189 Bit Score: 269.04 E-value: 7.44e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 355 GFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDK------QRQSQEMMALYKAEKVNPLGGCFPLII 428
Cdd:cd19751 1 GLSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYKEKAskdkvqQEMQKEMLGLYKKHGVNPMAGCLPLFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 429 QMPIFLALYYMLMGSIELRHAPFaLWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVT-----DPMQQKIMTFMPVIFT 503
Cdd:cd19751 81 QLPIFMAFYFAIMRTEEIRYHTF-LWFFDLGQPDYLYILPFVAGITTYFQFKMTMSHQQqmqmmQMQMKVMLYVMPVMII 159
|
170 180 190
....*....|....*....|....*....|
gi 1880759852 504 VFFLWFPSGLVLYYIVSNLVTIIQQQLIYR 533
Cdd:cd19751 160 IAGLSFPSALSLYWIISNLFMIIQTYFIVR 189
|
|
| EcYidC-like_peri |
cd19961 |
periplasmic beta-super sandwich fold domain of membrane protein insertase YidC from ... |
59-330 |
3.26e-68 |
|
periplasmic beta-super sandwich fold domain of membrane protein insertase YidC from Escherichia coli and similar domains; This subfamily is composed of Escherichia coli YidC and similar proteins. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC belongs to the YidC/Oxa1/Alb3 protein family of insertases that contain a core domain of five transmembrane (TM) segments that is essential to insertase function. In addition to this core transmembrane domain, YidC from Gram-negative bacteria contain an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. This periplasmic domain may have a role in protein assembly: a region of YidC that binds to SecF maps to one edge of the beta-super sandwich.
Pssm-ID: 411000 Cd Length: 255 Bit Score: 220.65 E-value: 3.26e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 59 KLITVKTDVLDLTINTRGGDVEQASLPAYPKELGSTEPFQLLEttPQFIYQAQSGLTGRDGPDNPANgpRPLYNVEKDAF 138
Cdd:cd19961 1 KRITVETDLLKASISTKGGRIKSVELKKYKETLPDSKPVELLS--PDGPYVAQLGLIGADGPLIPTA--DLLFTADSGSY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 139 vlaDGQNELQIPMTYTDAAGNTFTKTFVLKRGEYAVNVNYSVQNAGEKPLEVSTFGQLKQsinlpsHRDTGSSNFALHTF 218
Cdd:cd19961 77 ---EGGDSLTVTLTWTNGDGLTIEKTYTFDPDSYLIDVEVRVENNSSAPLSLSLYLQLQR------KGGEPEGSGSTITY 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 219 RGAAYsTPDEKYEKYKFDTIAENEnlNVNAKDGWVAMLQQYFATAWVPRNDGTNNFYTANLGNGIaAIGYKSQPVLVQPG 298
Cdd:cd19961 148 EGPAG-TEDGKLEKLSFKDLEEEK--LSSGKVGWVAFKQKYFLSALIPDQGFFYSAKLSGKDDGD-GVKLLSAALTLPPG 223
|
250 260 270
....*....|....*....|....*....|..
gi 1880759852 299 QTGAMTSTLWVGPEIQDKMAAVAPHLDLTVDY 330
Cdd:cd19961 224 GSGTFSFRLYAGPKDYDILKAYGPGLELAVDF 255
|
|
| PRK01001 |
PRK01001 |
putative inner membrane protein translocase component YidC; Provisional |
331-540 |
1.33e-50 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234887 [Multi-domain] Cd Length: 795 Bit Score: 185.77 E-value: 1.33e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 331 GWLWFISQP----LFKLLKWIHSFLGNWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQ 406
Cdd:PRK01001 549 GFFSFITEPfaalLFIIMKFFKFLTGSWGISIILLTVFLKLLLYPLNAWSIRSMRRMQKLSPYIQEIQQKYKKEPKRAQM 628
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 407 EMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPF-ALWIHDLSAQD--------------PYYILPILM 471
Cdd:PRK01001 629 EIMALYKTNKVNPITGCLPLLIQLPFLIAMFDLLKSSFLLRGASFiPGWIDNLTAPDvlfswetpiwfignEFHLLPILL 708
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1880759852 472 GVTMFFIQKMSPTTVTDPM-----QQKIM-TFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGL 540
Cdd:PRK01001 709 GVVMFAQQKISSLKRKGPVtdqqrQQEAMgTMMALLFTFMFYNFPSGLNIYWLSSMLLGVIQQWVTNKILDSKHL 783
|
|
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
345-548 |
3.73e-49 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 169.54 E-value: 3.73e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 345 KWIHSFLGNWGFS----IIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPL 420
Cdd:PRK00145 18 GFVSSVISNPNFSygiaIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKYKNDPQKLQQEMMKLYKEKGVNPL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 421 GGCFPLIIQMPIFLALYYMLMGSIELRHAPFaLWIHDLSAQDPYYILPILMGVTMFFIQKMspTTVTDPMQQKIMTFMPV 500
Cdd:PRK00145 98 GGCLPLLIQWPILIALYYVFNNLTGINGVSF-LWIKDLAKPDITWILPILSGATTYLSGYL--MTKADSSQAGQMKTMNI 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1880759852 501 IFTVFFLW----FPSGLVLYYIVSNLVTIIQQQLIYRgLEKRglHSREKKNS 548
Cdd:PRK00145 175 GMSIFMGVmswkFKSALVLYWVIGNLIQIIQTYFIKK-LELK--KKVEAKAA 223
|
|
| YidC_peri |
cd19960 |
periplasmic beta-super sandwich fold domain of membrane protein insertase YidC from ... |
59-329 |
2.37e-47 |
|
periplasmic beta-super sandwich fold domain of membrane protein insertase YidC from Gram-negative bacteria and similar domains; Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC belongs to the YidC/Oxa1/Alb3 protein family of insertases that contains a core domain of five transmembrane (TM) segments that is essential to insertase function. In addition to this core transmembrane domain, YidC from Gram-negative bacteria contain an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. This periplasmic domain may have a role in protein assembly: a region of YidC that binds to SecF maps to one edge of the beta-super sandwich. Other members of the YidC/Oxa1/Alb3 family include YidC1/YidC2 from gram-positive bacteria as well as eukaryotic members such as mitochondrial Oxa1/Oxa2 (or Cox18) and chloroplastic Alb3/Alb4; they are not part of this hierarchy as they do not possess the periplasmic domain.
Pssm-ID: 410999 Cd Length: 233 Bit Score: 164.73 E-value: 2.37e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 59 KLITVKTDVLDLTINTRGgDVEQASLPAYPKElgSTEPFQLLETTPQfiyqAQSGLTGRDGPD--NPANGPRPLYNVEKD 136
Cdd:cd19960 1 IIATVKSKDFELTIDTLG-RISQFYLKDKKYK--NEDGKQLELISPQ----APKPLEIRFSDPalNEEAFKTPYTASVSE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 137 afvLADGQNELQIPMTYTDAaGNTFTKTFVLKR-GEYAVNVNYSvqnagekpLEVSTFGQLKQSINLPShrdtgssnfAL 215
Cdd:cd19960 74 ---IDLESGPQSVVLTQTLS-GLTVTKTITFYPdGHYDVKVKLS--------KPVDYFITPGQRPNAAV---------DS 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 216 HTFRGAAYSTPDEKYEKYKFDtiaENENLNVNAKDGWVAMLQQYFATAWVPRNDGTNNFYTANlgngiaaigyKSQPVLV 295
Cdd:cd19960 133 YTVHGALVKTADGTITIIEDG---DAEGTESFSNVNIAASFDRYYATLFYNFDKGLNVVVTKD----------ASDNPLV 199
|
250 260 270
....*....|....*....|....*....|....
gi 1880759852 296 QPGQTGAMTSTLWVGPEIQDKMAAVAPHLDLTVD 329
Cdd:cd19960 200 FVKGNGNFSLHGYIGPKEYKLLKSIDPELTDVIE 233
|
|
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
332-531 |
2.90e-44 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 157.24 E-value: 2.90e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 332 WLWFISQPLFKLLKWIHSFLG-NWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDD----KQRQSQ 406
Cdd:PRK02944 36 WNEYFVYPLSQLITYFANLFGsNYGLAIIVVTLLIRLLILPLMIKQTKSTKAMQALQPEMQKLKEKYSSKdqatQQKLQQ 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 407 EMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFaLWIhDLSAQDPYYILPILMGVTMFFIQK-MSPTT 485
Cdd:PRK02944 116 EMMQLFQKNGVNPLAGCLPIFIQMPILIAFYHAIMRTSEISKHSF-LWF-DLGQADPYYILPIVAGITTFIQQKlMMAGT 193
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1880759852 486 VTDPMQQKIMTF-MPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLI 531
Cdd:PRK02944 194 AGQNPQMAMMLWlMPIMILIFAINFPAALSLYWVVGNIFMIAQTYLI 240
|
|
| PRK01315 |
PRK01315 |
putative inner membrane protein translocase component YidC; Provisional |
334-533 |
5.36e-42 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234941 Cd Length: 329 Bit Score: 153.36 E-value: 5.36e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 334 WFISQPLFkLLKWIHSFLGN------WGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQE 407
Cdd:PRK01315 17 WVISGILV-LFHTLLGFLFGpdsgltWVLSIVGLVIVIRALLIPLFVKQIKSQRNMQEIQPKMKKIQEKYKGDRERMSQE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 408 MMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIElRHAPFALWIHDL--SAQDPYY-------------------- 465
Cdd:PRK01315 96 MMKLYKETGTNPLSSCLPLLLQMPIFFALYRVLDSAAS-RGDGIGPINPPLleSFRHAHIfgaplaatflqalnagntav 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 466 -----ILPILMGVTMFFIQK------MSPTTVTDPM--QQKIMTFM-PVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLI 531
Cdd:PRK01315 175 qvvaaVLIILMSASQFITQLqlmtknMPPEAKTGPMaqQQKMLLYLfPLMFLVSGIAFPVGVLFYWLTSNVWTMGQQFYV 254
|
..
gi 1880759852 532 YR 533
Cdd:PRK01315 255 IR 256
|
|
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
318-537 |
4.93e-41 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 148.75 E-value: 4.93e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 318 AAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFL-GNWGFSIIVITFIVRGIMYPLTKAQYTSM----AKMRMLQPKIQA 392
Cdd:PRK01622 23 CSNAAPIDAHSDGFFDHYFVYPFSFLIQFVAHHIgGSYGIAIIIVTLIIRSLMIPLAVSQYKSQrgmqEKMAVMKPELDK 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 393 MRERLGD----DKQRQSQ-EMMALYKAEKVNPLG-GCFPLIIQMPIFLALYYMLMGSIELRHAPFaLWIhDLSAQDpyYI 466
Cdd:PRK01622 103 IQAKLKVtkdlEKQKEYQkEMMELYKSGNINPLAmGCLPLLIQMPILSAFYYAIRRTEEIASHSF-LWF-NLGHAD--HI 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1880759852 467 LPILMGVtMFFIQ-KMSPTTVTDPMQQ---KIMTFM-PVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEK 537
Cdd:PRK01622 179 LPIIAGL-TYFIQmKVSQSNGTSPEQVqmlKIQGIMmPAMILFMSFAAPSALVLYWITGGLFLMGQTIVLRKVMER 253
|
|
| 5TM_Oxa1-like |
cd20069 |
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ... |
354-530 |
9.54e-40 |
|
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410993 [Multi-domain] Cd Length: 201 Bit Score: 143.43 E-value: 9.54e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 354 WGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERL------GDDKQRQ--SQEMMALYKAEKVNPLGGCFP 425
Cdd:cd20069 4 WWATIAATTVALRLLLLPLVIKSQRNAARMANLQPELQKLQEKLkearasGDQLEAAeaRKELKELMKKHNVNPLKSLLL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 426 LIIQMPIFLALYYMLMGSIELRHAPF----ALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQ-----KIMT 496
Cdd:cd20069 84 PLVQAPVFISFFFALRKMANLPVPSFktggLLWFTDLTVPDPYYILPILTSLTFLATIELGAETGTSGSPQsktmkNVFR 163
|
170 180 190
....*....|....*....|....*....|....
gi 1880759852 497 FMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQL 530
Cdd:cd20069 164 GLPVLMIPFTANFPSAVFLYWITSNLFSLAQNLL 197
|
|
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
330-531 |
9.07e-28 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 113.29 E-value: 9.07e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 330 YGWLW-FISQPLFKLLKWIHSFLG-NWGFSIIVITFIVRGIMYPLT-----KAQYTSmAKMRMLQPKIQAMRERLG---- 398
Cdd:PRK02463 34 TGFIWnFLGAPMSYFIDYFANNLGlGFGLAIIIVTIIVRLIILPLGlyqswKATYQS-EKMAYLKPVFEPINERLKnatt 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 399 -DDKQRQSQEMMALYKAEKVNPLG--GCFPLIIQMPIFLALYYMLMGSIELRHAPFaLWIhDLSAQDpyYILPILMGVTM 475
Cdd:PRK02463 113 qEEKMAAQTELMAAQRENGISMLGgiGCLPLLIQMPFFSALYFAAQYTKGVSTSTF-LGI-DLGSPS--LVLTAIIGVLY 188
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1880759852 476 FFIQKMSPTTVTDPMQQKIMTF---MPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLI 531
Cdd:PRK02463 189 FFQSWLSMMGVPEEQREQMKAMmymMPIMMVVFSFSSPAGVGLYWLVGGFFSIIQQLIT 247
|
|
| PRK03449 |
PRK03449 |
putative inner membrane protein translocase component YidC; Provisional |
332-537 |
1.98e-27 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 179580 Cd Length: 304 Bit Score: 112.08 E-value: 1.98e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 332 WLWFisqplfkllkWIHSFLGN------WGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQS 405
Cdd:PRK03449 14 WFWH----------KLFSFVLGpdngfaWALSVMFLVFTLRALLYKPFVRQIRTTRKMQELQPQIKALQKKYGNDRQKMA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 406 QEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYML--------------MGSIELRH---------------------AP 450
Cdd:PRK03449 84 LEMQKLQKEHGFNPILGCLPMLAQIPVFLGLFHVLrsfnrtgtgfgqlgMSVEENRNtpnyvfsaedvqsfldarlfgAP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 451 FALWIHDLSAQDPYYI-------------LPILMGVTMFF-----IQKMSPTTVTDP---MQQKIMT-FMP--VIFTVFF 506
Cdd:PRK03449 164 LSAYITMPRSGLDAFVdftrtniilvgvpLMIIAGVATHFnsrasVARQSAEAAANPqtaMMNKLALwVFPlgVLVGGPF 243
|
250 260 270
....*....|....*....|....*....|.
gi 1880759852 507 LwfPSGLVLYYIVSNLVTIIQQQLIYRGLEK 537
Cdd:PRK03449 244 L--PLAILLYWVSNNIWTFGQQHYVFGKIDK 272
|
|
| PRK02654 |
PRK02654 |
putative inner membrane protein translocase component YidC; Provisional |
353-499 |
1.44e-24 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235058 Cd Length: 375 Bit Score: 105.45 E-value: 1.44e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 353 NWGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA----MRERLGDDKQRQSQEMMALYKaEKVNPLGGCFPLII 428
Cdd:PRK02654 26 SYGLAIVALTLVIRFALYPLSAGSIRNMRRMKIAQPVMQKrqaeIQERYKNDPQKQQEEMGKLMK-EFGNPLAGCLPLLV 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1880759852 429 QMPIFLALYYMLMGSielrhaPFALWIHDLSAQdpyyILP---ILMGVTMFFIQKMSPTTVTDPMQQKIMTFMP 499
Cdd:PRK02654 105 QMPILFALFATLRGS------PFADVNYTVNLQ----VLPseqIAAVQPQPFKSKPQNIFITDGVHFPVIASLP 168
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
325-532 |
3.35e-19 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 89.30 E-value: 3.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 325 DLTVDYG-WLWFISQPLFKLLKWIHSFLGNWG-------FSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPK---IQAM 393
Cdd:PRK02201 96 SWTWKYGpFYGLFVYPIAQIILSIMASQSLSElygwstiLAIIVVVLIIRLISFLITFKSTFNQEKQEELQGKkakIDAK 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 394 RERLGDD---KQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFaLWIhDLSAQdPY------ 464
Cdd:PRK02201 176 YKDYKKDkqmKQRKQQEIQELYKKHNISPFSPFVQMFVTLPIFIAVYRVVQSLPSIKVTTW-LGI-DLSAT-SWqeifag 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 465 ---YILPILMGVTMFFIQKMSPT----------TVTD------PMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTI 525
Cdd:PRK02201 253 nwiYLPILIIVVPVQALSQLLPQilnkkknkerTLNVkekealKKQNKTQNIISIVFIFFGVIFAAGVQIYWIIGGIWTI 332
|
....*..
gi 1880759852 526 IQQQLIY 532
Cdd:PRK02201 333 LQTLGIH 339
|
|
| PRK00247 |
PRK00247 |
putative inner membrane protein translocase component YidC; Validated |
339-538 |
7.81e-15 |
|
putative inner membrane protein translocase component YidC; Validated
Pssm-ID: 178945 [Multi-domain] Cd Length: 429 Bit Score: 76.81 E-value: 7.81e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 339 PLFKLLKWIHSFLGN---------WGFSIIVITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQS-QEM 408
Cdd:PRK00247 8 PVSGVMKLWHLLLHNvlglddslaWFASLFGLVITVRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKGKTDEASiREL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 409 MALYK-AEK---VNPLGGCFPLIIQMPIFLALYYMLM------GSIEL-RHAPFALwihdLSAQD--------------P 463
Cdd:PRK00247 88 QQKQKdLNKeygYNPLAGCVPALIQIPVFLGLYQVLLrmarpeGGLENpVHQPIGF----LTSEEvesflqgrvfnvplP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1880759852 464 YY---------------------ILPILMGVTMFFIQKMSPTTVTDPMQ-----------QKIMTFMPVIFTVFFLW--- 508
Cdd:PRK00247 164 AYvsmpaeqlaylgttqatvlafVLPLFIAAAVFTAINMAMSTYRSFQTndhdsgfavgmLKFLIVMAILAPIFPLSlgl 243
|
250 260 270
....*....|....*....|....*....|...
gi 1880759852 509 ---FPSGLVLYYIVSNLVTIIQQQLIYRGLEKR 538
Cdd:PRK00247 244 tgpFPTAIALYWVANNLWTLIQNIIMYLILERK 276
|
|
| |
