NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1881484931|gb|QMG02914|]
View 

multidrug efflux RND transporter permease AcrD [Escherichia coli]

Protein Classification

efflux RND transporter permease subunit( domain architecture ID 11484794)

efflux RND transporter permease subunit is an efflux membrane protein similar to Escherichia coli aminoglycoside efflux pump AcrD, which participates in the efflux of aminoglycosides and confers resistance to a variety of these substances

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK10555 PRK10555
multidrug efflux RND transporter permease AcrD;
1-1037 0e+00

multidrug efflux RND transporter permease AcrD;


:

Pssm-ID: 182544 [Multi-domain]  Cd Length: 1037  Bit Score: 2235.07  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:PRK10555     1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
Cdd:PRK10555    81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
Cdd:PRK10555   161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  241 QTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHG 320
Cdd:PRK10555   241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVL 400
Cdd:PRK10555   321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL 480
Cdd:PRK10555   401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  481 SVLVAMILTPALCATLLKPLKKGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPT 560
Cdd:PRK10555   481 SVLVAMILTPALCATLLKPLKKGEHHGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPT 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSKT 640
Cdd:PRK10555   561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSKT 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLD 720
Cdd:PRK10555   641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNPELTRVRHNGLD 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  721 DSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS 800
Cdd:PRK10555   721 DSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  801 AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL 880
Cdd:PRK10555   801 AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  881 VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA 960
Cdd:PRK10555   881 VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA 960
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1881484931  961 TLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRPE 1037
Cdd:PRK10555   961 TLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLVRRRFPLKPRPE 1037
 
Name Accession Description Interval E-value
PRK10555 PRK10555
multidrug efflux RND transporter permease AcrD;
1-1037 0e+00

multidrug efflux RND transporter permease AcrD;


Pssm-ID: 182544 [Multi-domain]  Cd Length: 1037  Bit Score: 2235.07  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:PRK10555     1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
Cdd:PRK10555    81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
Cdd:PRK10555   161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  241 QTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHG 320
Cdd:PRK10555   241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVL 400
Cdd:PRK10555   321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL 480
Cdd:PRK10555   401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  481 SVLVAMILTPALCATLLKPLKKGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPT 560
Cdd:PRK10555   481 SVLVAMILTPALCATLLKPLKKGEHHGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPT 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSKT 640
Cdd:PRK10555   561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSKT 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLD 720
Cdd:PRK10555   641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNPELTRVRHNGLD 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  721 DSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS 800
Cdd:PRK10555   721 DSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  801 AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL 880
Cdd:PRK10555   801 AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  881 VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA 960
Cdd:PRK10555   881 VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA 960
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1881484931  961 TLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRPE 1037
Cdd:PRK10555   961 TLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLVRRRFPLKPRPE 1037
2A0602 TIGR00915
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ...
1-1037 0e+00

The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 273335 [Multi-domain]  Cd Length: 1044  Bit Score: 1878.66  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:TIGR00915    1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
Cdd:TIGR00915   81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
Cdd:TIGR00915  161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  241 QTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHG 320
Cdd:TIGR00915  241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVL 400
Cdd:TIGR00915  321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL 480
Cdd:TIGR00915  401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  481 SVLVAMILTPALCATLLKPLKKGEHHGQK-GFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLP 559
Cdd:TIGR00915  481 SVLVALILTPALCATMLKPIEKGEHHEKKgGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSK 639
Cdd:TIGR00915  561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  640 TGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGL 719
Cdd:TIGR00915  641 ENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALTRVRPNGL 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  720 DDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPF 799
Cdd:TIGR00915  721 EDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVPF 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  800 SAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISL 879
Cdd:TIGR00915  801 SAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALSL 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  880 LVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFE 959
Cdd:TIGR00915  881 LVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVE 960
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1881484931  960 ATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRPE 1037
Cdd:TIGR00915  961 AALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEK 1038
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
1-1027 0e+00

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 1475.99  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:pfam00873    1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSgTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
Cdd:pfam00873   81 QSS-YGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYG-SQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLggtpsvDKQALNATINAQSL 239
Cdd:pfam00873  160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  240 LQTPEQFRDITLRvNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPH 319
Cdd:pfam00873  234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  320 GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMV 399
Cdd:pfam00873  313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  400 LAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMV 479
Cdd:pfam00873  393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  480 LSVLVAMILTPALCATLLKPLKKGEHHgqkGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLP 559
Cdd:pfam00873  473 LSVLVALTLTPALCATLLKPRREPKHG---GFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIP 549
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYftHEKDNIMSVFATVGSGPGG--NGQNVARMFIRLKDWSERD 637
Cdd:pfam00873  550 TEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKIL--KEKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKERP 627
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  638 SKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQD-HAGAGHDALMAARNQLLALAAENPELTRVRH 716
Cdd:pfam00873  628 GPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPGLSDVRS 707
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  717 NGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGM 796
Cdd:pfam00873  708 DGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKM 787
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  797 VPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQ--LPNGFGLEWTAMSYQERLSGAQAPAL 874
Cdd:pfam00873  788 IPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLPIL 867
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  875 YAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMN-QK 953
Cdd:pfam00873  868 IALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELReQE 947
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1881484931  954 GHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVR 1027
Cdd:pfam00873  948 GKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
1-1030 0e+00

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 1280.04  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:COG0841      3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSgTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDgsMDKQDIADYVAS 160
Cdd:COG0841     83 TSS-EGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGtpsvdkQALNATINAQSL 239
Cdd:COG0841    160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNGR 233
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  240 LQTPEQFRDITLRVNqDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPH 319
Cdd:COG0841    234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  320 GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMV 399
Cdd:COG0841    313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  400 LAIGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMV 479
Cdd:COG0841    393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  480 LSVLVAMILTPALCATLLKPlkkGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLP 559
Cdd:COG0841    472 ISLFVALTLTPALCARLLKP---HPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLP 548
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYftHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSk 639
Cdd:COG0841    549 TEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEIL--LEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDR- 625
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  640 tgTSFAIIERATKAFNKIKEARVIASSPPAiSGLGSSAGFDMELQdhaGAGHDALMAARNQLLALAAENPELTRVRHNGL 719
Cdd:COG0841    626 --SADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDVRSDLQ 699
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  720 DDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPF 799
Cdd:COG0841    700 LGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPL 779
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  800 SAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQ--LPNGFGLEWTAMSYQERLSGAQAPALYAI 877
Cdd:COG0841    780 SSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAFLL 859
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  878 SLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDL 957
Cdd:COG0841    860 ALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSL 939
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1881484931  958 FEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF 1030
Cdd:COG0841    940 REAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLR 1012
RND_permease_2 NF033617
multidrug efflux RND transporter permease subunit;
5-1028 0e+00

multidrug efflux RND transporter permease subunit;


Pssm-ID: 411236 [Multi-domain]  Cd Length: 1009  Bit Score: 759.55  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    5 FIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSG 84
Cdd:NF033617     4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSL 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   85 tGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTvRKTG--DTNILTIAFVSTdgSMDKQDIADYVASNI 162
Cdd:NF033617    84 -GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVY-RKANsaDTPIMYIGLTSE--EMPRGQLTDYAERVL 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  163 QDPLSRVNGVGDIDAYGSQY-SMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQlggtpsVDKQALNATINAQSLLQ 241
Cdd:NF033617   160 APKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGA------VRGDSVVSTVRANDQLK 233
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  242 TPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHGL 321
Cdd:NF033617   234 TAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNI 313
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  322 EYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLA 401
Cdd:NF033617   314 KVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLA 393
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  402 IGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVLS 481
Cdd:NF033617   394 IGLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  482 VLVAMILTPALCATLLKPLKKGEHhgqkgffawFNQMFNRNAERYEKGVAKILHRSL--RWIVIYVLL--LGGMVFLFLR 557
Cdd:NF033617   473 GIVALTLTPMMCSRLLKANEKPGR---------FARAVDRFFDGLTARYGRGLKWVLkhRPLTLVVALatLALLPLLYVF 543
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  558 LPTSFLPLEDRGMFTTSVQLPSGS-------TQQQTLKVVEQIEKYYFThekdnimSVFATVGsgpGGNGQNVARMFIRL 630
Cdd:NF033617   544 IPKELAPSEDRGVIFGMIQAPQSIsldymsaKMRDVEKILSSDPEVQSL-------TSFNGVG---GNPGDNTGFGIINL 613
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  631 KDWSERDSktgTSFAIIERATKAFNKIKEARVIASSPPAISGlgsSAGFDMELQDHA--GAGHDALMAARNQLLALAAEN 708
Cdd:NF033617   614 KPWDERDV---SAQEIIDRLRPKLAKVPGMDLFLFPLQDLPG---GAGSSLPQYQVTltPSDYDSLFTWAEKLKEKLRKS 687
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  709 PELTRVRHNGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWY 788
Cdd:NF033617   688 PQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIY 767
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  789 VRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMD-IMESLVKQLPNGFGLEWTAMSYQERLS 867
Cdd:NF033617   768 VRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEaLDQAAKELLPSGISGSFQGAARAFQEE 847
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  868 GAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFA 947
Cdd:NF033617   848 GSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFA 927
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  948 NEMN-QKGHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLV 1026
Cdd:NF033617   928 NELQrHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLL 1007

                   ..
gi 1881484931 1027 RR 1028
Cdd:NF033617  1008 AR 1009
 
Name Accession Description Interval E-value
PRK10555 PRK10555
multidrug efflux RND transporter permease AcrD;
1-1037 0e+00

multidrug efflux RND transporter permease AcrD;


Pssm-ID: 182544 [Multi-domain]  Cd Length: 1037  Bit Score: 2235.07  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:PRK10555     1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
Cdd:PRK10555    81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
Cdd:PRK10555   161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  241 QTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHG 320
Cdd:PRK10555   241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVL 400
Cdd:PRK10555   321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL 480
Cdd:PRK10555   401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  481 SVLVAMILTPALCATLLKPLKKGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPT 560
Cdd:PRK10555   481 SVLVAMILTPALCATLLKPLKKGEHHGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPT 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSKT 640
Cdd:PRK10555   561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSKT 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLD 720
Cdd:PRK10555   641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNPELTRVRHNGLD 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  721 DSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS 800
Cdd:PRK10555   721 DSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  801 AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL 880
Cdd:PRK10555   801 AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  881 VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA 960
Cdd:PRK10555   881 VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA 960
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1881484931  961 TLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRPE 1037
Cdd:PRK10555   961 TLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLVRRRFPLKPRPE 1037
2A0602 TIGR00915
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ...
1-1037 0e+00

The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 273335 [Multi-domain]  Cd Length: 1044  Bit Score: 1878.66  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:TIGR00915    1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
Cdd:TIGR00915   81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
Cdd:TIGR00915  161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  241 QTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHG 320
Cdd:TIGR00915  241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVL 400
Cdd:TIGR00915  321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL 480
Cdd:TIGR00915  401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  481 SVLVAMILTPALCATLLKPLKKGEHHGQK-GFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLP 559
Cdd:TIGR00915  481 SVLVALILTPALCATMLKPIEKGEHHEKKgGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSK 639
Cdd:TIGR00915  561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  640 TGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGL 719
Cdd:TIGR00915  641 ENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALTRVRPNGL 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  720 DDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPF 799
Cdd:TIGR00915  721 EDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVPF 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  800 SAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISL 879
Cdd:TIGR00915  801 SAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALSL 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  880 LVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFE 959
Cdd:TIGR00915  881 LVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQGKSIVE 960
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1881484931  960 ATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRPE 1037
Cdd:TIGR00915  961 AALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEK 1038
PRK15127 PRK15127
multidrug efflux RND transporter permease subunit AcrB;
1-1033 0e+00

multidrug efflux RND transporter permease subunit AcrB;


Pssm-ID: 185081 [Multi-domain]  Cd Length: 1049  Bit Score: 1553.34  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:PRK15127     1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
Cdd:PRK15127    81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
Cdd:PRK15127   161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  241 QTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHG 320
Cdd:PRK15127   241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVL 400
Cdd:PRK15127   321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL 480
Cdd:PRK15127   401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  481 SVLVAMILTPALCATLLKPLKKGEH-HGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLP 559
Cdd:PRK15127   481 SVLVALILTPALCATMLKPIAKGDHgEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSK 639
Cdd:PRK15127   561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  640 TGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPE-LTRVRHNG 718
Cdd:PRK15127   641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDmLVGVRPNG 720
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  719 LDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP 798
Cdd:PRK15127   721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  799 FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAIS 878
Cdd:PRK15127   801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQERLSGNQAPALYAIS 880
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  879 LLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANE-MNQKGHDL 957
Cdd:PRK15127   881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDlMDKEGKGL 960
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1881484931  958 FEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLK 1033
Cdd:PRK15127   961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRK 1036
ACR_tran pfam00873
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ...
1-1027 0e+00

AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.


Pssm-ID: 395701 [Multi-domain]  Cd Length: 1021  Bit Score: 1475.99  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:pfam00873    1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSgTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
Cdd:pfam00873   81 QSS-YGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYG-SQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLggtpsvDKQALNATINAQSL 239
Cdd:pfam00873  160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  240 LQTPEQFRDITLRvNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPH 319
Cdd:pfam00873  234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  320 GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMV 399
Cdd:pfam00873  313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  400 LAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMV 479
Cdd:pfam00873  393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  480 LSVLVAMILTPALCATLLKPLKKGEHHgqkGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLP 559
Cdd:pfam00873  473 LSVLVALTLTPALCATLLKPRREPKHG---GFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIP 549
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYftHEKDNIMSVFATVGSGPGG--NGQNVARMFIRLKDWSERD 637
Cdd:pfam00873  550 TEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKIL--KEKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKERP 627
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  638 SKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQD-HAGAGHDALMAARNQLLALAAENPELTRVRH 716
Cdd:pfam00873  628 GPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPGLSDVRS 707
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  717 NGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGM 796
Cdd:pfam00873  708 DGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKM 787
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  797 VPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQ--LPNGFGLEWTAMSYQERLSGAQAPAL 874
Cdd:pfam00873  788 IPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLPIL 867
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  875 YAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMN-QK 953
Cdd:pfam00873  868 IALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELReQE 947
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1881484931  954 GHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVR 1027
Cdd:pfam00873  948 GKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
AcrB COG0841
Multidrug efflux pump subunit AcrB [Defense mechanisms];
1-1030 0e+00

Multidrug efflux pump subunit AcrB [Defense mechanisms];


Pssm-ID: 440603 [Multi-domain]  Cd Length: 1015  Bit Score: 1280.04  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:COG0841      3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSgTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDgsMDKQDIADYVAS 160
Cdd:COG0841     83 TSS-EGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGtpsvdkQALNATINAQSL 239
Cdd:COG0841    160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNGR 233
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  240 LQTPEQFRDITLRVNqDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPH 319
Cdd:COG0841    234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  320 GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMV 399
Cdd:COG0841    313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  400 LAIGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMV 479
Cdd:COG0841    393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  480 LSVLVAMILTPALCATLLKPlkkGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLP 559
Cdd:COG0841    472 ISLFVALTLTPALCARLLKP---HPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLP 548
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYftHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSk 639
Cdd:COG0841    549 TEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEIL--LEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDR- 625
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  640 tgTSFAIIERATKAFNKIKEARVIASSPPAiSGLGSSAGFDMELQdhaGAGHDALMAARNQLLALAAENPELTRVRHNGL 719
Cdd:COG0841    626 --SADEIIARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDVRSDLQ 699
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  720 DDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPF 799
Cdd:COG0841    700 LGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPL 779
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  800 SAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQ--LPNGFGLEWTAMSYQERLSGAQAPALYAI 877
Cdd:COG0841    780 SSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAFLL 859
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  878 SLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDL 957
Cdd:COG0841    860 ALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSL 939
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1881484931  958 FEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF 1030
Cdd:COG0841    940 REAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLR 1012
PRK09577 PRK09577
multidrug efflux RND transporter permease subunit;
1-1036 0e+00

multidrug efflux RND transporter permease subunit;


Pssm-ID: 169981 [Multi-domain]  Cd Length: 1032  Bit Score: 1220.86  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
Cdd:PRK09577     1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   81 QSSgTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
Cdd:PRK09577    81 TSS-AGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
Cdd:PRK09577   160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  241 QTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHG 320
Cdd:PRK09577   240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVL 400
Cdd:PRK09577   320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL 480
Cdd:PRK09577   400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  481 SVLVAMILTPALCATLLKPLKkGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPT 560
Cdd:PRK09577   480 SAFLALSLTPALCATLLKPVD-GDHHEKRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPT 558
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKdnIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSKT 640
Cdd:PRK09577   559 AFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP--VAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAAR 636
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  641 GTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLD 720
Cdd:PRK09577   637 DHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDPALTDLMFAGTQ 716
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  721 DSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS 800
Cdd:PRK09577   717 DAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVPLA 796
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  801 AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL 880
Cdd:PRK09577   797 AFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERLSGAQAPMLFALSVL 876
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  881 VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA 960
Cdd:PRK09577   877 VVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADA 956
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1881484931  961 TLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRP 1036
Cdd:PRK09577   957 ALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRLFDVGPRR 1032
RND_permease_2 NF033617
multidrug efflux RND transporter permease subunit;
5-1028 0e+00

multidrug efflux RND transporter permease subunit;


Pssm-ID: 411236 [Multi-domain]  Cd Length: 1009  Bit Score: 759.55  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    5 FIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSG 84
Cdd:NF033617     4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSL 83
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   85 tGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTvRKTG--DTNILTIAFVSTdgSMDKQDIADYVASNI 162
Cdd:NF033617    84 -GYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVY-RKANsaDTPIMYIGLTSE--EMPRGQLTDYAERVL 159
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  163 QDPLSRVNGVGDIDAYGSQY-SMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQlggtpsVDKQALNATINAQSLLQ 241
Cdd:NF033617   160 APKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGA------VRGDSVVSTVRANDQLK 233
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  242 TPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHGL 321
Cdd:NF033617   234 TAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNI 313
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  322 EYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLA 401
Cdd:NF033617   314 KVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLA 393
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  402 IGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVLS 481
Cdd:NF033617   394 IGLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  482 VLVAMILTPALCATLLKPLKKGEHhgqkgffawFNQMFNRNAERYEKGVAKILHRSL--RWIVIYVLL--LGGMVFLFLR 557
Cdd:NF033617   473 GIVALTLTPMMCSRLLKANEKPGR---------FARAVDRFFDGLTARYGRGLKWVLkhRPLTLVVALatLALLPLLYVF 543
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  558 LPTSFLPLEDRGMFTTSVQLPSGS-------TQQQTLKVVEQIEKYYFThekdnimSVFATVGsgpGGNGQNVARMFIRL 630
Cdd:NF033617   544 IPKELAPSEDRGVIFGMIQAPQSIsldymsaKMRDVEKILSSDPEVQSL-------TSFNGVG---GNPGDNTGFGIINL 613
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  631 KDWSERDSktgTSFAIIERATKAFNKIKEARVIASSPPAISGlgsSAGFDMELQDHA--GAGHDALMAARNQLLALAAEN 708
Cdd:NF033617   614 KPWDERDV---SAQEIIDRLRPKLAKVPGMDLFLFPLQDLPG---GAGSSLPQYQVTltPSDYDSLFTWAEKLKEKLRKS 687
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  709 PELTRVRHNGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWY 788
Cdd:NF033617   688 PQFADVDSDLQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIY 767
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  789 VRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMD-IMESLVKQLPNGFGLEWTAMSYQERLS 867
Cdd:NF033617   768 VRSNDGKLVPLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEaLDQAAKELLPSGISGSFQGAARAFQEE 847
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  868 GAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFA 947
Cdd:NF033617   848 GSSLLFLFLLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFA 927
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  948 NEMN-QKGHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLV 1026
Cdd:NF033617   928 NELQrHQGLSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLL 1007

                   ..
gi 1881484931 1027 RR 1028
Cdd:NF033617  1008 AR 1009
PRK09579 PRK09579
multidrug efflux RND transporter permease subunit;
5-1031 2.22e-180

multidrug efflux RND transporter permease subunit;


Pssm-ID: 169983 [Multi-domain]  Cd Length: 1017  Bit Score: 552.52  E-value: 2.22e-180
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    5 FIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSqSSG 84
Cdd:PRK09579     7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTS-VSR 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   85 TGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVStdGSMDKQDIADYVASNIQD 164
Cdd:PRK09579    86 QNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYS--EEMSNPQITDYLSRVIQP 163
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  165 PLSRVNGVGDIDAYGSQ-YSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGtpsvdkQALNATINAQSLLQTP 243
Cdd:PRK09579   164 KLATLPGMAEAEILGNQvFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKG------EYVVTSINASTELKSA 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  244 EQFRDITLRVNQDgSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHGLEY 323
Cdd:PRK09579   238 EAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKV 316
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  324 KVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLAIG 403
Cdd:PRK09579   317 SIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIG 396
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  404 LLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVL 483
Cdd:PRK09579   397 LVVDDAIVVVENIHRHI-EEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGI 475
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  484 VAMILTPALCATLLKPlkkgeHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFL 563
Cdd:PRK09579   476 VALTLSPMMCALLLRH-----EENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELA 550
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  564 PLEDRG---MFTTSVQLPS----GSTQQQTLKVVEQIEKYYFTHEkdniMSVFATVGSGPGGngqnvarmfIRLKDWSER 636
Cdd:PRK09579   551 PEEDQGiifMMSSSPQPANldylNAYTDEFTPIFKSFPEYYSSFQ----INGFNGVQSGIGG---------FLLKPWNER 617
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  637 DSktgTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELqdHAGAGHDALMAARNQLLALAAENPELTRVRH 716
Cdd:PRK09579   618 ER---TQMELLPLVQAKLEEIPGLQIFGFNLPSLPGTGEGLPFQFVI--NTANDYESLLQVAQRVKQRAQESGKFAFLDI 692
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  717 NGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGM 796
Cdd:PRK09579   693 DLAFDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQL 772
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  797 VPFSAFATSRWETGSPRLERYNGYSAVEIVGeaAPGVSTGTAMDIMESLVK-QLPNGFGLEWTAMSYQERLSGAQAPALY 875
Cdd:PRK09579   773 LPLSTLITLSDRARPRQLNQFQQLNSAIISG--FPIVSMGEAIETVQQIAReEAPEGFAFDYAGASRQYVQEGSALWVTF 850
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  876 AISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEM-NQKG 954
Cdd:PRK09579   851 GLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLrHEQG 930
                          970       980       990      1000      1010      1020      1030
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1881484931  955 HDLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFP 1031
Cdd:PRK09579   931 LSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAKPDA 1007
CusA COG3696
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
4-1036 6.51e-153

Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];


Pssm-ID: 442911 [Multi-domain]  Cd Length: 1031  Bit Score: 480.68  E-value: 6.51e-153
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    4 FFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSqSS 83
Cdd:COG3696      8 FSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRS-IS 86
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   84 GTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQavqnqGVTVRKTGDTN----ILTIAFVSTDGS---MDKQDIAD 156
Cdd:COG3696     87 RFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPA-----GVTPELGPISTglgeIYQYTLESDPGKyslMELRTLQD 161
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  157 YVasnIQDPLSRVNGVGDIDAYG---SQYsmRIWLDPAKLNSFQMTAKDVTDAIESQNAQiaVGqlGGTPSVDKQALnaT 233
Cdd:COG3696    162 WV---IRPQLRSVPGVAEVNSFGgfvKQY--QVLVDPAKLRAYGLTLDDVIEALERNNAN--VG--GGYIERGGQEY--L 230
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  234 INAQSLLQTPEQFRDITLRvNQDGSEVRLGDVATVEMGAE-KYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDD 312
Cdd:COG3696    231 VRGIGLIRSLEDIENIVVK-TRNGTPVLLRDVAEVRIGPApRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAE 309
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  313 LAQYFPHGLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNT 392
Cdd:COG3696    310 LKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANL 389
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  393 LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATR-----KSMGQIQGALV-GIAMVLsAVFVPMAFFGGTTGAI 466
Cdd:COG3696    390 MSLGGLAIDFGIIVDGAVVMVENILRRLEENRAAGTPRERlevvlEAAREVRRPIFfATLIII-LVFLPIFTLEGVEGKL 468
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  467 YRQFSITIVAAMVLSVLVAMILTPALCATLLKPlKKGEHHGqkgffaWFNQMFNRnaeRYEKGVAKILHRSLRWIVIYVL 546
Cdd:COG3696    469 FRPMALTVIFALLGALLLSLTLVPVLASLLLRG-KVPEKEN------PLVRWLKR---LYRPLLRWALRHPKLVLAVALV 538
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  547 LLGGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYyfTHEKDNIMSVFATVGSGPGGN---GQNV 623
Cdd:COG3696    539 LLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERI--LKSFPEVESVVSRTGRAEDATdpmGVNM 616
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  624 ARMFIRLK---DWSERDSKTgtsfAIIERATKAFNKIKEARVIASSP------PAISGLGSS-----AGFDM-ELQDHAg 688
Cdd:COG3696    617 SETFVILKprsEWRSGRTKE----ELIAEMREALEQIPGVNFNFSQPiqmrvdELLSGVRADvavkiFGDDLdVLRRLA- 691
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  689 aghdalmaarNQLLALAAENPELTRV---RHNGLddsPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGR 765
Cdd:COG3696    692 ----------EQIEAVLKTVPGAADVqveRVTGL---PQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGER 758
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  766 VKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNG--YSAVEI----------VGEaapgv 833
Cdd:COG3696    759 RFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGrrRIVVQAnvrgrdlgsfVAE----- 833
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  834 stgtAMDIMESLVKqLPNGFGLEWTAMS-YQERlsgAQAPALYA--ISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGA 910
Cdd:COG3696    834 ----AQAKVAEQVK-LPPGYYIEWGGQFeNLQR---ATARLAIVvpLALLLIFLLLYLAFGSVRDALLILLNVPFALIGG 905
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  911 LLATWMRGLendvYFQ----VGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPILMTSLAFIFGVLPM 986
Cdd:COG3696    906 VLALWLRGM----PLSvsagVGFIALFGVAVLNGVVLVSYINQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPM 981
                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|
gi 1881484931  987 ATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRP 1036
Cdd:COG3696    982 ALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRAAA 1031
PRK10503 PRK10503
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
5-1031 2.28e-136

MdtB/MuxB family multidrug efflux RND transporter permease subunit;


Pssm-ID: 182501 [Multi-domain]  Cd Length: 1040  Bit Score: 437.24  E-value: 2.28e-136
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    5 FIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSG 84
Cdd:PRK10503    16 FILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSG 95
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   85 tGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVR-KTGDTNILTIAFVSTdgSMDKQDIADYVASNIQ 163
Cdd:PRK10503    96 -GASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKvNPADPPIMTLAVTST--AMPMTQVEDMVETRVA 172
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  164 DPLSRVNGVGDIDAYGSQY-SMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGG-TPSVdkqalnaTINAQSLLQ 241
Cdd:PRK10503   173 QKISQVSGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGpTRAV-------TLSANDQMQ 245
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  242 TPEQFRDITLRVnQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHGL 321
Cdd:PRK10503   246 SAEEYRQLIIAY-QNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSV 324
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  322 EYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLA 401
Cdd:PRK10503   325 KVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIA 404
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  402 IGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVLS 481
Cdd:PRK10503   405 TGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILIS 483
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  482 VLVAMILTPALCATLLKP--LKKgehhgQKGFFAWFNQMFNRNAERYEKGVAKILHRSlrWIVIYVLL--LGGMVFLFLR 557
Cdd:PRK10503   484 AVVSLTLTPMMCARMLSQesLRK-----QNRFSRASERMFDRVIAAYGRGLAKVLNHP--WLTLSVALstLLLTVLLWIF 556
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  558 LPTSFLPLEDRGMFTTSVQLPS----GSTQQQTLKVVEQIEKyyftheKDNIMSVFATVGSGPGGNGQNVARMFIRLKDW 633
Cdd:PRK10503   557 IPKGFFPVQDNGIIQGTLQAPQsssfANMAQRQRQVADVILQ------DPAVQSLTSFVGVDGTNPSLNSARLQINLKPL 630
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  634 SERDSKTGTsfaIIERATKAFNKIKEARVI--ASSPPAISGLGSSAGFDMELQdhaGAGHDALMAARNQLLALAAENPEL 711
Cdd:PRK10503   631 DERDDRVQK---VIARLQTAVAKVPGVDLYlqPTQDLTIDTQVSRTQYQFTLQ---ATSLDALSTWVPKLMEKLQQLPQL 704
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  712 TRVRHNGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQ---AAAPYRMLPDDINLwy 788
Cdd:PRK10503   705 SDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEhntENTPGLAALDTIRL-- 782
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  789 vRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQL--PNGFGLEW--TAMSYQE 864
Cdd:PRK10503   783 -TSSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLnlPADITTQFqgSTLAFQS 861
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  865 RLSGAQAPALYAIslLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIV 944
Cdd:PRK10503   862 ALGSTVWLIVAAV--VAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMI 939
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  945 EF--ANEMNQkGHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLF 1022
Cdd:PRK10503   940 DFalAAEREQ-GMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVI 1018
                         1050
                   ....*....|....*.
gi 1881484931 1023 FVL-------VRRRFP 1031
Cdd:PRK10503  1019 YLLfdrlalyTKSRFP 1034
PRK10614 PRK10614
multidrug efflux system subunit MdtC; Provisional
5-1037 3.44e-127

multidrug efflux system subunit MdtC; Provisional


Pssm-ID: 182589 [Multi-domain]  Cd Length: 1025  Bit Score: 412.20  E-value: 3.44e-127
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931    5 FIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSg 84
Cdd:PRK10614     7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSS- 85
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   85 TGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGvTVRKT--GDTNILTIAFVSTDGSmdKQDIADYVASNI 162
Cdd:PRK10614    86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKAnpSDAPIMILTLTSDTYS--QGQLYDFASTQL 162
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  163 QDPLSRVNGVGDIDAYGSQY-SMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGqlggtpSVDKQALNATINAQSLLQ 241
Cdd:PRK10614   163 AQTISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQG------AVEDGTHRWQIQTNDELK 236
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  242 TPEQFRDITLRVNQdGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPHGL 321
Cdd:PRK10614   237 TAAEYQPLIIHYNN-GAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAI 315
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  322 EYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLA 401
Cdd:PRK10614   316 DLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIA 395
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  402 IGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVLS 481
Cdd:PRK10614   396 TGFVVDDAIVVLENISRHL-EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGIS 474
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  482 VLVAMILTPALCATLLKPLKKGEHHGQKGffawFNQMFNRNAERYEKGVAKILHRSlRWI-VIYVLLLGGMVFLFLRLPT 560
Cdd:PRK10614   475 LLVSLTLTPMMCAWLLKSSKPREQKRLRG----FGRMLVALQQGYGRSLKWVLNHT-RWVgVVLLGTIALNVWLYISIPK 549
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKyyFTHEKDNIMSVFATVgsgpGGNGQNVARMFIRLKDWSERDSkt 640
Cdd:PRK10614   550 TFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMK--IIRDDPAVDNVTGFT----GGSRVNSGMMFITLKPLSERSE-- 621
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  641 gTSFAIIERATKAFNKIKEAR--VIASSPPAISGLGSSAGFDMELQDhagaghDALMAARN---QLLALAAENPELTRVR 715
Cdd:PRK10614   622 -TAQQVIDRLRVKLAKEPGANlfLMAVQDIRVGGRQSNASYQYTLLS------DDLAALREwepKIRKALAALPELADVN 694
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  716 HNGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGG 795
Cdd:PRK10614   695 SDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINNEGK 774
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  796 MVPFSAFAtsRWE-TGSPRLERYNGYSAVE-IVGEAAPGVSTGTAMDIMESLVKQL--PNGF--GLEWTAMSYQERLSGA 869
Cdd:PRK10614   775 AIPLSYFA--KWQpANAPLSVNHQGLSAAStISFNLPTGKSLSDASAAIERAMTQLgvPSTVrgSFAGTAQVFQETMNSQ 852
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  870 QAPALYAISllVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANE 949
Cdd:PRK10614   853 LILILAAIA--TVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALE 930
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  950 MNQKGH-DLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVP---LFFVL 1025
Cdd:PRK10614   931 AQRNGNlTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPvvyLFFDR 1010
                         1050
                   ....*....|..
gi 1881484931 1026 VRRRFPLKPRPE 1037
Cdd:PRK10614  1011 LRLRFSRKPKQT 1022
2A0601 TIGR00914
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ...
10-1029 6.77e-91

heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 129992 [Multi-domain]  Cd Length: 1051  Bit Score: 313.62  E-value: 6.77e-91
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   10 IFAWVLAILlcltGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSgTGQAS 89
Cdd:TIGR00914   18 LATLVMAIL----GIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSR-YGLSQ 92
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931   90 VTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVrKTGDTNILTIAFVSTDGSMDKQDIADYVAS--NIQD--- 164
Cdd:TIGR00914   93 VTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPI-STGLGEIFLYTVEAEEGARKKDGGAYTLTDlrTIQDwii 171
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  165 --PLSRVNGVGDIDAYG---SQYSMRIwlDPAKLNSFQMTAKDVTDAIESQNAQIavgqlgGTPSVDKQALNATINAQSL 239
Cdd:TIGR00914  172 rpQLRTVPGVAEVNSIGgyvKQFLVAP--DPEKLAAYGLSLADVVNALERNNQNV------GAGYIERRGEQYLVRAPGQ 243
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  240 LQTPEQFRDITLRvNQDGSEVRLGDVATVEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDDLAQYFPH 319
Cdd:TIGR00914  244 VQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPE 322
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  320 GLEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAmv 399
Cdd:TIGR00914  323 GVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGA-- 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  400 LAIGLLVDDAIVVVENVERIMSE----EGLTPREATR-----KSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQF 470
Cdd:TIGR00914  401 LDFGLIVDGAVVIVENAHRRLAEaqhhHGRQLTLKERlhevfAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPM 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  471 SITIVAAMVLSVLVAMILTPALCATLL-KPLKKGEhhgqkgffawfNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLG 549
Cdd:TIGR00914  481 AFTVVLALAGAMILSLTFVPAAVALFIrGKVAEKE-----------NRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIV 549
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  550 GMVFLFLRLPTSFLPLEDRGMFT-TSVQLPsGSTQQQTLKVVEQIEKYYFTHEKdnIMSVFATVGSGPGGNGQ---NVAR 625
Cdd:TIGR00914  550 LVVWIASRVGGEFIPSLNEGDLAyQALRIP-GTSLAQSVAMQQTLEKLIKSFPE--VARVFAKTGTAEIATDPmppNASD 626
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  626 MFIRLKDWSE-RDSKTGTSFAIIERATKAfnkikeARVIAS----SPPA-------ISGLGSSAGFDMelqdhAGAGHDA 693
Cdd:TIGR00914  627 TYIILKPESQwPEGKKTKEDLIEEIQEAT------VRIPGNnyefTQPIqmrfnelISGVRSDVAVKV-----FGDDLDD 695
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  694 LMAARNQLLALAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQA 773
Cdd:TIGR00914  696 LDATAEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRL 775
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  774 AAPYRMLPD-----DINLWYVRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAApGVSTGTAMDIMESLVK- 847
Cdd:TIGR00914  776 PESLRESPQalrqlPIPLPLSEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVR-GRDLGSFVDDAKKAIAe 854
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  848 --QLPNGFGLEWTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYF 925
Cdd:TIGR00914  855 qvKLPPGYWITWGGQFEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISA 934
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  926 QVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVM 1005
Cdd:TIGR00914  935 AVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVI 1014
                         1050      1060
                   ....*....|....*....|....
gi 1881484931 1006 GGMISATILAIYFVPLFFVLVRRR 1029
Cdd:TIGR00914 1015 GGIITATLLTLFVLPALYRLVHRR 1038
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
311-1031 1.98e-25

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 113.42  E-value: 1.98e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  311 DDLAQYFPHGLEYKV---AYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFG 387
Cdd:COG1033    188 AIIAKYEDPGVEVYLtgfPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLG 267
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  388 YSVNTLTMFAMVLAIGLLVDDAIVVvenVERIMSE--EGLTPREATRKSMGQiqgalVGIAMVLSAV-----FVPMAFfg 460
Cdd:COG1033    268 IPLSPLTILVPPLLLAIGIDYGIHL---LNRYREErrKGLDKREALREALRK-----LGPPVLLTSLttaigFLSLLF-- 337
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  461 gTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQKGFFAWFNQMFNRNAERYEKGVakilhrslrw 540
Cdd:COG1033    338 -SDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLAKLARFVLRRPKVI---------- 406
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  541 IVIYVLLLGGMVFLFLRLPTSFLPLEDrgmfttsvqLPSGSTQQQTLKVVEqiEKYyfthekDNIMSVFATVGSGPGG-- 618
Cdd:COG1033    407 LVVALVLAVVSLYGISRLKVEYDFEDY---------LPEDSPIRQDLDFIE--ENF------GGSDPLEVVVDTGEPDgl 469
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  619 -NGQNVARMfIRLKDWSERDSKTGTSFAI---IERATKAFNKIKEA-RVIASSPPAISglgssagfdmelqdhagaghda 693
Cdd:COG1033    470 kDPEVLKEI-DRLQDYLESLPEVGKVLSLadlVKELNQALNEGDPKyYALPESRELLA---------------------- 526
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  694 lmaarnQLLALAAENPELTRVRhnglddspqlQIDIDQRKAQALgVAIDDIndtlqtawGSSYVNDFMDRgrvkkvyVQA 773
Cdd:COG1033    527 ------QLLLLLSSPPGDDLSR----------FVDEDYSAARVT-VRLKDL--------DSEEIKALVEE-------VRA 574
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  774 AAPYRMLPDDINlwyvrnkdggmvpfsafatsrwetgsprleryngysaVEIVGEAapgvstGTAMDIMESLVKQLPNGF 853
Cdd:COG1033    575 FLAENFPPDGVE-------------------------------------VTLTGSA------VLFAAINESVIESQIRSL 611
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  854 GLewtamsyqerlsgaqapalyaiSLLVVFLCLAALYESWSVPFSVML--VVPLGVIGALLAtWMrglenDVYFQVGLLT 931
Cdd:COG1033    612 LL----------------------ALLLIFLLLLLAFRSLRLGLISLIpnLLPILLTFGLMG-LL-----GIPLNIATAV 663
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  932 V----IGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATSTGagsGGQHAVGTGVMGG 1007
Cdd:COG1033    664 VasiaLGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSF---PPLADFGLLLALG 740
                          730       740
                   ....*....|....*....|....
gi 1881484931 1008 MISATILAIYFVPLFFVLVRRRFP 1031
Cdd:COG1033    741 LLVALLAALLLLPALLLLLDPRIA 764
YdfJ COG2409
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ...
295-592 4.37e-13

Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];


Pssm-ID: 441964 [Multi-domain]  Cd Length: 697  Bit Score: 73.65  E-value: 4.37e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  295 SGANEMATAELVLNRLDDLAQYFPHGLEYKV---AYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIA 371
Cdd:COG2409    123 DGDAGDEAAEAVDALRDAVAAAPAPGLTVYVtgpAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLT 202
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  372 VPVVLMGTFSVLYAFGYSV---NTLTMFAMVLAIGLLVDDAIVVV----ENVERimseeGLTPREATRKSMGQIQ----- 439
Cdd:COG2409    203 AGLAVGVALGLLALLAAFTdvsSFAPNLLTMLGLGVGIDYALFLVsryrEELRA-----GEDREEAVARAVATAGravlf 277
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  440 -GALVGIAMvLSAVFVPMAFFggttgaiyRQFSITIVAAMVLSVLVAMILTPALCATL-------LKPLKKGEHHGQKGF 511
Cdd:COG2409    278 sGLTVAIAL-LGLLLAGLPFL--------RSMGPAAAIGVAVAVLAALTLLPALLALLgrrvfwpRRPRRRRAAAPESGF 348
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  512 FAWFnqmfnrnaeryekgVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFlPLEDrgmfttsvQLPSGSTQQQTLKVVE 591
Cdd:COG2409    349 WRRL--------------ARAVVRRPVPVLVAAVAVLLALALPALGLRLGL-PDAD--------SLPADSPSRQGYDALA 405

                   .
gi 1881484931  592 Q 592
Cdd:COG2409    406 E 406
MMPL pfam03176
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ...
332-496 4.07e-09

MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.


Pssm-ID: 308676 [Multi-domain]  Cd Length: 332  Bit Score: 59.61  E-value: 4.07e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  332 FVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGY----SVNTLT-MFAMVLAIGLLV 406
Cdd:pfam03176  136 LRDAGDRDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAQGLVAILAHilgiGLSTFAlNLLVVLLIAVGT 215
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  407 DDAIVVvenVERIMSE--EGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFfggTTGAIYRQFSITIVAAMVLSVLV 484
Cdd:pfam03176  216 DYALFL---VSRYREElrAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSF---ARLPVFAQVGPTIAIGVLVDVLA 289
                          170
                   ....*....|..
gi 1881484931  485 AMILTPALCATL 496
Cdd:pfam03176  290 ALTLLPALLALL 301
2A0601 TIGR00914
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ...
150-508 2.68e-08

heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 129992 [Multi-domain]  Cd Length: 1051  Bit Score: 58.23  E-value: 2.68e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  150 DKQDIADyVASNIQDPLSRVNGVGDIDA---YGSQYsMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQL-GGTPSV 225
Cdd:TIGR00914  692 DLDDLDA-TAEKISAVLKGVPGAADVKVeqtTGLPY-LTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETfEGDRRF 769
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  226 DkqalnatINaqslLQTPEQFRD---------ITLRVNQDG--SEVRLGDVATVEMgAEKYDYLSRFNGKPASGL----- 289
Cdd:TIGR00914  770 D-------IV----IRLPESLREspqalrqlpIPLPLSEDArkQFIPLSDVADLRV-SPGPNQISRENGKRRVVVsanvr 837
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  290 GVKLASGANEMATaelvlnRLDDLAQyFPHG--LEYKVAYETTSFVKASIEDVVKTlleAIALVFLVMYLFLQNFRATLI 367
Cdd:TIGR00914  838 GRDLGSFVDDAKK------AIAEQVK-LPPGywITWGGQFEQLQSATKRLQIVVPV---TLLLIFVLLYAAFGNVKDALL 907
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  368 PTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLAIGLLVDDAIVVVENVeRIMSEEGLTPREATrksmgqIQGALVGI-- 445
Cdd:TIGR00914  908 VFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFI-RKLLEEGPSLDEAV------YEGALTRVrp 980
                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1881484931  446 ----AMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQ 508
Cdd:TIGR00914  981 vlmtALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHRRRHKGRKEHE 1047
MMPL COG1033
Predicted exporter protein, RND superfamily [General function prediction only];
876-1037 1.69e-07

Predicted exporter protein, RND superfamily [General function prediction only];


Pssm-ID: 440656 [Multi-domain]  Cd Length: 767  Bit Score: 55.25  E-value: 1.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  876 AISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGAL-LATWMrGLENDVYFQV--GLLTVIGLSakNAI-LIVEFANEMn 951
Cdd:COG1033    225 PLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLgLMGLL-GIPLSPLTILvpPLLLAIGID--YGIhLLNRYREER- 300
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  952 QKGHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATStgaGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFP 1031
Cdd:COG1033    301 RKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFS---DIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKP 377

                   ....*.
gi 1881484931 1032 LKPRPE 1037
Cdd:COG1033    378 KTRRLK 383
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
317-492 3.59e-07

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 54.46  E-value: 3.59e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  317 FPHGLEYKVAYE---TTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPtiaVPVVLMG---TFSVLYAFGYSV 390
Cdd:TIGR00921  169 PPSGKFLDVTGSpaiNYDIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLP---LVIILFGvawVLGIMGWLGIPL 245
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  391 NTLTMFAMVLAIGLLVDDAIVVVENVERiMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAiyrQF 470
Cdd:TIGR00921  246 YATTLLAVPMLIGVGIDYGIQTLNRYEE-ERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVS---EF 321
                          170       180
                   ....*....|....*....|..
gi 1881484931  471 SITIVAAMVLSVLVAMILTPAL 492
Cdd:TIGR00921  322 GLGLVAGLITAYLLTLLVLPAL 343
SecD COG0342
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ...
336-502 2.06e-06

Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440111 [Multi-domain]  Cd Length: 434  Bit Score: 51.27  E-value: 2.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  336 SIEDVVKTLLEAIALVFLVMYLFLQNFRatLIPTIAVPVVLMGTFSVLYAFGYsvnTLTM---FAMVLAIGLLVDDaivv 412
Cdd:COG0342    269 SIEKGLIAGLIGLLLVALFMLLYYRLPG--LVANIALALNVVLLLGVLSLLGA---TLTLpgiAGIILTIGMAVDA---- 339
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  413 veNV---ERIMSE--EGLTPREAT----RKSMGQIQGALV--GIAMvlsavfVPMAFFGgtTGAIyRQFSITIVAAMVLS 481
Cdd:COG0342    340 --NVlifERIREElrAGRSLRAAIeagfKRAFSTILDANVttLIAA------VVLFVLG--TGPV-KGFAVTLILGILIS 408
                          170       180
                   ....*....|....*....|...
gi 1881484931  482 VLVAMILTPALCATLL--KPLKK 502
Cdd:COG0342    409 MFTAVPVTRPLLNLLLgrRRLKK 431
Patched pfam02460
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ...
339-492 1.65e-05

Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.


Pssm-ID: 308203 [Multi-domain]  Cd Length: 793  Bit Score: 48.89  E-value: 1.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  339 DVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLAIGLLVDDAIVVVENver 418
Cdd:pfam02460  640 STIQNIVITLICMFIVCFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYH--- 716
                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1881484931  419 IMSEEGLTPREATRKSMGQI-----QGALVGIAMVLSAVFVPmaffggtTGAIyRQFSITIVAAMVLSVLVAMILTPAL 492
Cdd:pfam02460  717 FVRSRGDTPAERVVDALEALgwpvfQGGLSTILGVLVLLFVP-------SYMV-VVFFKTVFLVVAIGLLHGLFILPII 787
secD TIGR01129
protein-export membrane protein SecD; Members of this family are highly variable in length ...
324-492 3.42e-05

protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273456 [Multi-domain]  Cd Length: 397  Bit Score: 47.28  E-value: 3.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  324 KVAYETT---SFVKASIEDVVKTLLEAIALVFLVMYLFLQNFraTLIPTIAVPVVLMGTFSVLYAFGYsvnTLTM---FA 397
Cdd:TIGR01129  231 QILEERTigpSLGADSIEAGIKAGLIGLVLVLVFMILYYRLF--GLIAAIALVINIVLILAILSAFGA---TLTLpgiAG 305
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  398 MVLAIGLLVDDAIVVvenVERIMSE--EGLTPREAT----RKSMGQIQGAlvGIAMVLSAVFvpMAFFGgtTGAIyRQFS 471
Cdd:TIGR01129  306 LILTIGMAVDANVLI---YERIKEElrLGKSVRQAIeagfERAFSTIFDA--NITTLIAALI--LYVFG--TGPV-KGFA 375
                          170       180
                   ....*....|....*....|.
gi 1881484931  472 ITIVAAMVLSVLVAMILTPAL 492
Cdd:TIGR01129  376 VTLAIGIIASLFTALVFTRLL 396
2A0604s01 TIGR00916
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ...
331-485 4.88e-05

protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273336 [Multi-domain]  Cd Length: 192  Bit Score: 45.33  E-value: 4.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  331 SFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRA-TLIPTIAVPVVLmgTFSVLYAFGYSVNTLTMFAMVLAIGLLVDDA 409
Cdd:TIGR00916   40 TLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAiAAIAALVHDVIL--ILGVLSLFGATLTLPGIAGLLTIIGYSVDDT 117
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  410 IVVVENV-ERIMSEEGLTPREATRKSmgqIQGALVGIAMVLSAVFVPMA---FFGGttGAIyRQFSITIVAAMVLSVLVA 485
Cdd:TIGR00916  118 VVIFDRIrEELRKYKGRTFREAINLG---INQTLSRIIDTNVTTLLAVLalyVFGG--GAI-KGFALTLGIGVIAGTYSS 191
HpnN TIGR03480
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ...
334-565 5.04e-05

hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.


Pssm-ID: 274598 [Multi-domain]  Cd Length: 862  Bit Score: 47.30  E-value: 5.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  334 KASIEDVVKTLLEAIALVFLVMYLFLQNFR---ATLIPTIAVPVVLMGtFSVLyAFGySVNTLTMFAMVLAIGLLVDDAI 410
Cdd:TIGR03480  265 ATVSEGATVAGLLSFVLVLVLLWLALRSPRlvfAVLVTLIVGLILTAA-FATL-AVG-HLNLISVAFAVLFIGLGVDFAI 341
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  411 VVV----ENVERimseeGLTPREATRKSMGQIQGALVgIAMVLSAV----FVPMAFFGgttgaiYRQFSITIVAAMVLSV 482
Cdd:TIGR03480  342 QFSlryrEERFR-----GGNHREALSVAARRMGAALL-LAALATAAgffaFLPTDYKG------VSELGIIAGTGMFIAL 409
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  483 LVAMILTPALCaTLLKPLKKGEHHGqkgfFAWFnqmfnrnaeryeKGVAKILHRSLRWIVIYVLLLG-GMVFLFLRLPTS 561
Cdd:TIGR03480  410 FVTLTVLPALL-RLLRPPRRRKPPG----YATL------------APLDAFLRRHRRPVLGVTLILGiAALALLPQLRFD 472

                   ....
gi 1881484931  562 FLPL 565
Cdd:TIGR03480  473 FNPL 476
PRK13024 PRK13024
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
324-556 7.83e-05

bifunctional preprotein translocase subunit SecD/SecF; Reviewed


Pssm-ID: 237276 [Multi-domain]  Cd Length: 755  Bit Score: 46.76  E-value: 7.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  324 KVAYETT---SFVKASIEDVVKTLLEAIALVFLVMYLFLQnfRATLIPTIAVPVVLMGTFSVLYAFGysvNTLTM---FA 397
Cdd:PRK13024   249 KIIESRSvgpTLGQDAIDAGIIAGIIGFALIFLFMLVYYG--LPGLIANIALLLYIFLTLGALSSLG---AVLTLpgiAG 323
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  398 MVLAIGLLVDDAIVVvenVERIMSE--EGLTPREATRKSMgqiQGALVGIA-----MVLSAV--FvpmaFFGgtTGAIyR 468
Cdd:PRK13024   324 LVLGIGMAVDANVLI---FERIKEElrKGKSLKKAFKKGF---KNAFSTILdsnitTLIAAAilF----FFG--TGPV-K 390
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  469 QFSITIVAAMVLSVLVAMILTPALCATLLKPLKKgehhgqKGFFAWFNQMFNRNAERYEKGVAKI--LHRSLRWIVIYVL 546
Cdd:PRK13024   391 GFATTLIIGILASLFTAVFLTRLLLELLVKRGDK------KPFLFGVKKKKIHNINEGVTIFDRIdfVKKRKWFLIFSIV 464
                          250
                   ....*....|
gi 1881484931  547 LLGGMVFLFL 556
Cdd:PRK13024   465 LVIAGIIIFF 474
MMPL pfam03176
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ...
876-1037 3.04e-04

MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.


Pssm-ID: 308676 [Multi-domain]  Cd Length: 332  Bit Score: 44.20  E-value: 3.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  876 AISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGA--LLATWMRGLENDVY-FQVGLLTVIGLSAKN--AILIVEFANEM 950
Cdd:pfam03176  149 AVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAqgLVAILAHILGIGLStFALNLLVVLLIAVGTdyALFLVSRYREE 228
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  951 NQKGHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATstgAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF 1030
Cdd:pfam03176  229 LRAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSF---ARLPVFAQVGPTIAIGVLVDVLAALTLLPALLALLGRWG 305

                   ....*..
gi 1881484931 1031 PLKPRPE 1037
Cdd:pfam03176  306 LWPPKRD 312
YdfJ COG2409
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ...
289-497 1.00e-03

Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];


Pssm-ID: 441964 [Multi-domain]  Cd Length: 697  Bit Score: 43.22  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  289 LGVKLASGANEMATAELVlNRLDDLAQYFPHGLEYKVAYETTSFV---KASIEDVVKTLLEAIALVFLVMYLFlqnFRAt 365
Cdd:COG2409    466 LQVVPDGDPDSPEAIDLV-DRLRDAAAPALEGAEVLVGGTTAVNIdisDALADDLPLVIPVVLGLIFLLLLLL---FRS- 540
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  366 liptIAVPVVLMGTF--SVLYAFGYSV------------------NTLTMFAMVLAIGLLVDDAIVVVEnveRIM--SEE 423
Cdd:COG2409    541 ----VVAPLKAVLTNllSLGAALGVLVlvfqhgwlllgftpgpldSFVPLLLFVILFGLGMDYEVFLVS---RIReeYDR 613
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1881484931  424 GLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTgaiYRQFSITIVAAMVL-SVLVAMILTPALcATLL 497
Cdd:COG2409    614 GGGTREAVIRGLARTGRVITSAALIMAAVFAAFATSPLVF---LKQIGFGLAVGVLLdAFVVRMLLVPAL-MALL 684
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
850-1020 5.10e-03

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 40.98  E-value: 5.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  850 PNGFGLEWT---AMSYQ-ERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYF 925
Cdd:TIGR00921  170 PSGKFLDVTgspAINYDiEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATT 249
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  926 QVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPILMTSLAFIFGVLPMATStgaGSGGQHAVGTGVM 1005
Cdd:TIGR00921  250 LLAVPMLIGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALS---EFPMVSEFGLGLV 326
                          170
                   ....*....|....*
gi 1881484931 1006 GGMISATILAIYFVP 1020
Cdd:TIGR00921  327 AGLITAYLLTLLVLP 341
MelB COG2211
Na+/melibiose symporter or related transporter [Carbohydrate transport and metabolism];
368-490 5.77e-03

Na+/melibiose symporter or related transporter [Carbohydrate transport and metabolism];


Pssm-ID: 441813 [Multi-domain]  Cd Length: 447  Bit Score: 40.27  E-value: 5.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1881484931  368 PTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVLAIGLLVDDAI-VVVENVERIMSEegLTPREATRKSMGQIQGALVGIA 446
Cdd:COG2211     82 PWILIGAIPLALSFVLLFTAPDLSPTGKLIYALVTYLLLGLAYtLVNIPYSALGAE--LTPDYEERTRLSSWRFAFAGLG 159
                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 1881484931  447 MVLSAVFVP--MAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTP 490
Cdd:COG2211    160 GLLASVLPPplVAAFGGDAALGYRLTALIFAVLGLLAFLLTFFGTK 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH