|
Name |
Accession |
Description |
Interval |
E-value |
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-257 |
0e+00 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 539.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 1 MSM-VDTAPGKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNI 79
Cdd:COG1117 1 MTApASTLEPKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMNDLIPGARVEGEILLDGEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 80 LTNTQDIALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQ 159
Cdd:COG1117 81 YDPDVDVVELRRRVGMVFQKPNPFPKSIYDNVAYGLRLHGIKSKSELDEIVEESLRKAALWDEVKDRLKKSALGLSGGQQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:COG1117 161 QRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQI 240
|
250
....*....|....*...
gi 1897751821 240 FTKPAKKQTEDYITGRYG 257
Cdd:COG1117 241 FTNPKDKRTEDYITGRFG 258
|
|
| 3a0107s01c2 |
TIGR00972 |
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ... |
10-256 |
1.02e-165 |
|
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]
Pssm-ID: 273372 [Multi-domain] Cd Length: 247 Bit Score: 457.91 E-value: 1.02e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 10 KIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNTQDIALL 89
Cdd:TIGR00972 1 AIEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLNRMNDLVPGVRIEGKVLFDGQDIYDKKIDVVEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIA 169
Cdd:TIGR00972 81 RRRVGMVFQKPNPFPMSIYDNIAYGPRLHGIKDKKELDEIVEESLKKAALWDEVKDRLHDSALGLSGGQQQRLCIARALA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQTE 249
Cdd:TIGR00972 161 VEPEVLLLDEPTSALDPIATGKIEELIQELKKKYTIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNPKEKRTE 240
|
....*..
gi 1897751821 250 DYITGRY 256
Cdd:TIGR00972 241 DYISGRF 247
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
11-239 |
1.29e-144 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 403.87 E-value: 1.29e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNTQDIALLR 90
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGAPDEGEVLLDGKDIYDLDVDVLELR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHqsGYSLSGGQQQRLCIARGIAI 170
Cdd:cd03260 81 RRVGMVFQKPNPFPGSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALWDEVKDRLH--ALGLSGGQQQRLCLARALAN 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 171 RPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:cd03260 159 EPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
10-257 |
3.69e-129 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 366.41 E-value: 3.69e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 10 KIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNTQDIALL 89
Cdd:PRK14243 10 VLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLIPGFRVEGKVTFHGKNLYAPDVDPVEV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFPMSIYDNIAFGVRLfeKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIA 169
Cdd:PRK14243 90 RRRIGMVFQKPNPFPKSIYDNIAYGARI--NGYKGDMDELVERSLRQAALWDEVKDKLKQSGLSLSGGQQQRLCIARAIA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFM---------YLGELIEFSNTDDLF 240
Cdd:PRK14243 168 VQPEVILMDEPCSALDPISTLRIEELMHELKEQYTIIIVTHNMQQAARVSDMTAFFnveltegggRYGYLVEFDRTEKIF 247
|
250
....*....|....*..
gi 1897751821 241 TKPAKKQTEDYITGRYG 257
Cdd:PRK14243 248 NSPQQQATRDYVSGRFG 264
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
11-257 |
4.29e-119 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 340.21 E-value: 4.29e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNTQDIALLR 90
Cdd:PRK14239 6 LQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAI 170
Cdd:PRK14239 86 KEIGMVFQQPNPFPMSIYENVVYGLRLKGIKDKQVLDEAVEKSLKGASIWDEVKDRLHDSALGLSGGQQQRVCIARVLAT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 171 RPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQTED 250
Cdd:PRK14239 166 SPKIILLDEPTSALDPISAGKIEETLLGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNPKHKETED 245
|
....*..
gi 1897751821 251 YITGRYG 257
Cdd:PRK14239 246 YISGKFG 252
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
11-257 |
1.30e-104 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 303.69 E-value: 1.30e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNTQDIALLR 90
Cdd:PRK14267 5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNEEARVEGEVRLFGRNIYSPDVDPIEVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKL--SRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARG 167
Cdd:PRK14267 85 REVGMVFQYPNPFPhLTIYDNVAIGVKL-NGLvkSKKELDERVEWALKKAALWDEVKDRLNDYPSNLSGGQRQRLVIARA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQ 247
Cdd:PRK14267 164 LAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENPEHEL 243
|
250
....*....|
gi 1897751821 248 TEDYITGRYG 257
Cdd:PRK14267 244 TEKYVTGALG 253
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
10-255 |
1.74e-99 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 290.66 E-value: 1.74e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 10 KIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTntQDIALL 89
Cdd:PRK14247 3 KIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIELYPEARVSGEVYLDGQDIFK--MDVIEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKL-SRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARG 167
Cdd:PRK14247 81 RRRVQMVFQIPNPIPnLSIFENVALGLKLNRLVkSKKELQERVRWALEKAQLWDEVKDRLDAPAGKLSGGQQQRLCIARA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQ 247
Cdd:PRK14247 161 LAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHEL 240
|
....*...
gi 1897751821 248 TEDYITGR 255
Cdd:PRK14247 241 TEKYVTGR 248
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
11-257 |
2.24e-91 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 270.37 E-value: 2.24e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNTQDIALLR 90
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESEVRVEGRVEFFNQNIYERRVNLNRLR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAI 170
Cdd:PRK14258 88 RQVSMVHPKPNLFPMSVYDNVAYGVKIVGWRPKLEIDDIVESALKDADLWDEIKHKIHKSALDLSGGQQQRLCIARALAV 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 171 RPEVLLLDEPCSALDPISTGRIEELI--TELKEDYTVVIVTHNMQQAARCSDHTAFMY-----LGELIEFSNTDDLFTKP 243
Cdd:PRK14258 168 KPKVLLMDEPCFGLDPIASMKVESLIqsLRLRSELTMVIVSHNLHQVSRLSDFTAFFKgnenrIGQLVEFGLTKKIFNSP 247
|
250
....*....|....
gi 1897751821 244 AKKQTEDYITGRYG 257
Cdd:PRK14258 248 HDSRTREYVLSRLG 261
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
11-252 |
1.85e-76 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 231.42 E-value: 1.85e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILTNTQDIALLR 90
Cdd:COG1126 2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLL-----EEPDSGTITVDGEDLTDSKKDINKLR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIA 169
Cdd:COG1126 77 RKVGMVFQQFNLFPhLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGL----ADKADAYPAQLSGGQQQRVAIARALA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQT 248
Cdd:COG1126 153 MEPKVMLFDEPTSALDPELVGEVLDVMRDLaKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQHERT 232
|
....
gi 1897751821 249 EDYI 252
Cdd:COG1126 233 RAFL 236
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
4-257 |
1.50e-71 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 220.35 E-value: 1.50e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 4 VDTAPGKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILtNT 83
Cdd:PRK14271 15 VDAAAPAMAAVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSIF-NY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 84 QDIALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLC 163
Cdd:PRK14271 94 RDVLEFRRRVGMLFQRPNPFPMSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEVGLWDAVKDRLSDSPFRLSGGQQQLLC 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKP 243
Cdd:PRK14271 174 LARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSP 253
|
250
....*....|....
gi 1897751821 244 AKKQTEDYITGRYG 257
Cdd:PRK14271 254 KHAETARYVAGLSG 267
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
1-255 |
7.58e-71 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 217.99 E-value: 7.58e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 1 MSMVDTAPGKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQ-RAEGEILLDGDNI 79
Cdd:PRK14246 1 MEAGKSAEDVFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKiKVDGKVLYFGKDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 80 LTntQDIALLRAKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQ 158
Cdd:PRK14246 81 FQ--IDAIKLRKEVGMVFQQPNPFPhLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRLNSPASQLSGGQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDD 238
Cdd:PRK14246 159 QQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNE 238
|
250
....*....|....*..
gi 1897751821 239 LFTKPAKKQTEDYITGR 255
Cdd:PRK14246 239 IFTSPKNELTEKYVIGR 255
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
11-225 |
2.03e-70 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 215.47 E-value: 2.03e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILTNTQDIALLR 90
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLL-----EEPDSGTIIIDGLKLTDDKKNINELR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIA 169
Cdd:cd03262 76 QKVGMVFQQFNLFPhLTVLENITLAPIKVKGMSKAEAEERALELLEKVGL----ADKADAYPAQLSGGQQQRVAIARALA 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFM 225
Cdd:cd03262 152 MNPKVMLFDEPTSALDPELVGEVLDVMKDLaEEGMTMVVVTHEMGFAREVADRVIFM 208
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
11-243 |
1.42e-67 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 217.46 E-value: 1.42e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY-----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILT-NTQ 84
Cdd:COG1123 261 LEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGL-----LRPTSGSILFDGKDLTKlSRR 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIALLRAKVGMVFQKPT----PFpMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKL-HQsgysLSGGQQ 159
Cdd:COG1123 336 SLRELRRRVQMVFQDPYsslnPR-MTVGDIIAEPLRLHGLLSRAERRERVAELLERVGLPPDLADRYpHE----LSGGQR 410
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTD 237
Cdd:COG1123 411 QRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELglTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTE 490
|
....*.
gi 1897751821 238 DLFTKP 243
Cdd:COG1123 491 EVFANP 496
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
11-243 |
5.56e-67 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 207.18 E-value: 5.56e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY-GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGDNIltNTQDIALL 89
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGL--LKPT---SGEVLVDGKDI--TKKNLREL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTP--FPMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALWnetkDKLHQSGYSLSGGQQQRLCIARG 167
Cdd:COG1122 74 RRKVGLVFQNPDDqlFAPTVEEDVAFGPENL-GLPREEIRERVEEALELVGLE----HLADRPPHELSGGQKQRVAIAGV 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKP 243
Cdd:COG1122 149 LAMEPEVLVLDEPTAGLDPRGRRELLELLKRLnKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDY 225
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
11-241 |
5.79e-67 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 207.35 E-value: 5.79e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQRaeGEILLDGDNI--LTNTQDIAL 88
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRL---IVGLLRPDS--GEVLIDGEDIsgLSEAELYRL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 lRAKVGMVFQKPTPF-PMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARG 167
Cdd:cd03261 76 -RRRMGMLFQSGALFdSLTVFENVAFPLREHTRLSEEEIREIVLEKLEAVGL----RGAEDLYPAELSGGMKKRVALARA 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFT 241
Cdd:cd03261 151 LALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELglTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
11-241 |
6.33e-65 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 202.13 E-value: 6.33e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPEqraEGEILLDGDNILT-NTQDIALL 89
Cdd:COG1127 6 IEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLI--IGLLRPD---SGEILVDGQDITGlSEKELYEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPF-PMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwNETKDKL-HQsgysLSGGQQQRLCIARG 167
Cdd:COG1127 81 RRRIGMLFQGGALFdSLTVFENVAFPLREHTDLSEAEIRELVLEKLELVGL-PGAADKMpSE----LSGGMRKRVALARA 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFT 241
Cdd:COG1127 156 LALDPEILLYDEPTAGLDPITSAVIDELIRELRDELglTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLA 231
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-244 |
1.41e-63 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 202.25 E-value: 1.41e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 1 MSMVDtapgkIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRT---FnkmfelypEQRAEGEILLDGd 77
Cdd:COG3842 1 MAMPA-----LELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMiagF--------ETPDSGRILLDG- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 78 niltntQDIALLRA---KVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALtkaalwnetkDKLHQSGYS 153
Cdd:COG3842 67 ------RDVTGLPPekrNVGMVFQDYALFPhLTVAENVAFGLRM-RGVPKAEIRARVAELL----------ELVGLEGLA 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 154 ------LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPistGRIEELITELKE-----DYTVVIVTHNMQQAARCSDHT 222
Cdd:COG3842 130 dryphqLSGGQQQRVALARALAPEPRVLLLDEPLSALDA---KLREEMREELRRlqrelGITFIYVTHDQEEALALADRI 206
|
250 260
....*....|....*....|..
gi 1897751821 223 AFMYLGELIEFSNTDDLFTKPA 244
Cdd:COG3842 207 AVMNDGRIEQVGTPEEIYERPA 228
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
11-229 |
1.24e-62 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 194.33 E-value: 1.24e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqRAEGEILLDGDNILTNTQDIALLR 90
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEE-----PDSGSILIDGEDLTDLEDELPPLR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGvrlfeklsradmdervqwaltkaalwnetkdklhqsgysLSGGQQQRLCIARGIA 169
Cdd:cd03229 76 RRIGMVFQDFALFPhLTVLENIALG---------------------------------------LSGGQQQRVALARALA 116
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKED--YTVVIVTHNMQQAARCSDHTAFMYLGE 229
Cdd:cd03229 117 MDPDVLLLDEPTSALDPITRREVRALLKSLQAQlgITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-225 |
2.12e-60 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 191.46 E-value: 2.12e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 1 MSMvdtAPGKIQVRDLNFYY----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRT---FnkmfelypEQRAEGEIL 73
Cdd:COG1116 1 MSA---AAPALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLiagL--------EKPTSGEVL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 74 LDGdniltntQDIALLRAKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALwNETKDKL-HQsg 151
Cdd:COG1116 70 VDG-------KPVTGPGPDRGVVFQEPALLPwLTVLDNVALGLEL-RGVPKAERRERARELLELVGL-AGFEDAYpHQ-- 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 152 ysLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFM 225
Cdd:COG1116 139 --LSGGMRQRVAIARALANDPEVLLMDEPFGALDALTRERLQDELLRLwqETGKTVLFVTHDVDEAVFLADRVVVL 212
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
11-245 |
4.18e-60 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 197.82 E-value: 4.18e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPEQRAEGEILLDGDNILTntQDIAL 88
Cdd:COG1123 5 LEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALAL--MGLLPHGGRISGEVLLDGRDLLE--LSEAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKVGMVFQKPTP--FPMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIAR 166
Cdd:COG1123 81 RGRRIGMVFQDPMTqlNPVTVGDQIAEALENL-GLSRAEARARVLELLEAVGLERRLDRYPHQ----LSGGQRQRVAIAM 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:COG1123 156 ALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERgtTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQ 235
|
.
gi 1897751821 245 K 245
Cdd:COG1123 236 A 236
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
11-233 |
5.33e-60 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 188.88 E-value: 5.33e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIltntQDIALLR 90
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGL-----ERPDSGEILIDGRDV----TGVPPER 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIA 169
Cdd:cd03259 72 RNIGMVFQDYALFPhLTVAENIAFGLKL-RGVPKAEIRARVRELLELVGLEGLLNRYPHE----LSGGQQQRVALARALA 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 170 IRPEVLLLDEPCSALDPISTgriEELITELKE-----DYTVVIVTHNMQQAARCSDHTAFMYLGELIEF 233
Cdd:cd03259 147 REPSLLLLDEPLSALDAKLR---EELREELKElqrelGITTIYVTHDQEEALALADRIAVMNEGRIVQV 212
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
11-239 |
3.83e-59 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 187.19 E-value: 3.83e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGDNILTNTQDIallR 90
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGL--LRPT---SGEVRVLGEDVARDPAEV---R 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALWnetkDKLHQSGYSLSGGQQQRLCIARGIA 169
Cdd:COG1131 73 RRIGYVPQEPALYPdLTVRENLRFFARLY-GLPRKEARERIDELLELFGLT----DAADRKVGTLSGGMKQRLGLALALL 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:COG1131 148 HDPELLILDEPTSGLDPEARRELWELLRELAAEgKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
11-230 |
5.95e-59 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 185.79 E-value: 5.95e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIltNTQDIALLR 90
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADL-----DPPTSGEIYLDGKPL--SAMPPPEWR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFPMSIYDNIAFGVRLFEKlsRADMdERVQWALTKAALwneTKDKLHQSGYSLSGGQQQRLCIARGIAI 170
Cdd:COG4619 74 RQVAYVPQEPALWGGTVRDNLPFPFQLRER--KFDR-ERALELLERLGL---PPDILDKPVERLSGGERQRLALIRALLL 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 171 RPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGEL 230
Cdd:COG4619 148 QPDVLLLDEPTSALDPENTRRVEELLREYlaEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
12-225 |
1.25e-58 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 184.98 E-value: 1.25e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFH--ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIltNTQDIALL 89
Cdd:cd03225 1 ELKNLSFSYPDGArpALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGL-----LGPTSGEVLVDGKDL--TKLSLKEL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKP-TPFPM-SIYDNIAFGVRLFeKLSRADMDERVQWALTKAALWnetkDKLHQSGYSLSGGQQQRLCIARG 167
Cdd:cd03225 74 RRKVGLVFQNPdDQFFGpTVEEEVAFGLENL-GLPEEEIEERVEEALELVGLE----GLRDRSPFTLSGGQKQRVAIAGV 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFM 225
Cdd:cd03225 149 LAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAEgKTIIIVTHDLDLLLELADRVIVL 207
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
11-243 |
5.22e-58 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 185.73 E-value: 5.22e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK-----FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGDNILTNT-Q 84
Cdd:TIGR04521 1 IKLKNVSYIYQPgtpfeKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGL--LKPT---SGTVTIDGRDITAKKkK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIALLRAKVGMVFQKPTP--FPMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALwneTKDKLHQSGYSLSGGQQQRL 162
Cdd:TIGR04521 76 KLKDLRKKVGLVFQFPEHqlFEETVYKDIAFGPKNL-GLSEEEAEERVKEALELVGL---DEEYLERSPFELSGGQMRRV 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 163 CIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLF 240
Cdd:TIGR04521 152 AIAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKglTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVF 231
|
...
gi 1897751821 241 TKP 243
Cdd:TIGR04521 232 SDV 234
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
11-252 |
8.28e-58 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 184.04 E-value: 8.28e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFH-ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEqraEGEILLDGDNIltNTQDIALL 89
Cdd:cd03295 1 IEFENVTKRYGGGKkAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIE--PT---SGEIFIDGEDI--REQDPVEL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFP-MSIYDNIAFgVRLFEKLSRADMDERVQWALTKAALwnETKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:cd03295 74 RRKIGYVIQQIGLFPhMTVEENIAL-VPKLLKWPKEKIRERADELLALVGL--DPAEFADRYPHELSGGQQQRVGVARAL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKK 246
Cdd:cd03295 151 AADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELgkTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPAND 230
|
....*.
gi 1897751821 247 QTEDYI 252
Cdd:cd03295 231 FVAEFV 236
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
11-244 |
1.01e-57 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 187.28 E-value: 1.01e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkmfelypeqrA------EGEILLDGDNILTN-- 82
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRII-----------AgletpdSGRIVLNGRDLFTNlp 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 83 TQDiallRaKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERV-QWaLTKAALwnetkDKL-----HQsgysLS 155
Cdd:COG1118 72 PRE----R-RVGFVFQHYALFPhMTVAENIAFGLRV-RPPSKAEIRARVeEL-LELVQL-----EGLadrypSQ----LS 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 156 GGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEF 233
Cdd:COG1118 136 GGQRQRVALARALAVEPEVLLLDEPFGALDAKVRKELRRWLRRLHDELggTTVFVTHDQEEALELADRVVVMNQGRIEQV 215
|
250
....*....|.
gi 1897751821 234 SNTDDLFTKPA 244
Cdd:COG1118 216 GTPDEVYDRPA 226
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
11-241 |
1.74e-57 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 183.71 E-value: 1.74e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPeqrAEGEILLDGDNILT-NTQDIAll 89
Cdd:COG1120 2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAG--LLKP---SSGEVLLDGRDLASlSRRELA-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 rAKVGMVFQKPT-PFPMSIYDNIAFG----VRLFEKLSRADmDERVQWALTKAALWnetkDKLHQSGYSLSGGQQQRLCI 164
Cdd:COG1120 75 -RRIAYVPQEPPaPFGLTVRELVALGryphLGLFGRPSAED-REAVEEALERTGLE----HLADRPVDELSGGERQRVLI 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 165 ARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFT 241
Cdd:COG1120 149 ARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLarERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLT 227
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
9-244 |
1.06e-56 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 184.51 E-value: 1.06e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRT---FnkmfelypEQRAEGEILLDGdniltntQD 85
Cdd:COG3839 2 ASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMiagL--------EDPTSGEILIGG-------RD 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IALLRAK---VGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALtkaalwnetkDKLHQSGY------SLS 155
Cdd:COG3839 67 VTDLPPKdrnIAMVFQSYALYPhMTVYENIAFPLKL-RKVPKAEIDRRVREAA----------ELLGLEDLldrkpkQLS 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 156 GGQQQRLCIARGIAIRPEVLLLDEPCSALDPIStgRiEELITELKE-----DYTVVIVTHNMQQAARCSDHTAFMYLGEL 230
Cdd:COG3839 136 GGQRQRVALGRALVREPKVFLLDEPLSNLDAKL--R-VEMRAEIKRlhrrlGTTTIYVTHDQVEAMTLADRIAVMNDGRI 212
|
250
....*....|....
gi 1897751821 231 IEFSNTDDLFTKPA 244
Cdd:COG3839 213 QQVGTPEELYDRPA 226
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
11-233 |
1.87e-56 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 180.01 E-value: 1.87e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILTNTQDI 86
Cdd:cd03257 2 LEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGL-----LKPTSGSIIFDGKDLLKLSRRL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAK-VGMVFQKP----TPFpMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAAlwNETKDKLHQSGYSLSGGQQQR 161
Cdd:cd03257 77 RKIRRKeIQMVFQDPmsslNPR-MTIGEQIAEPLRIHGKLSKKEARKEAVLLLLVGV--GLPEEVLNRYPHELSGGQRQR 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 162 LCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEF 233
Cdd:cd03257 154 VAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELglTLLFITHDLGVVAKIADRVAVMYAGKIVEE 227
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
11-221 |
3.67e-55 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 176.51 E-value: 3.67e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYG----KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLR---TFnkmfelypEQRAEGEILLDGdniltnt 83
Cdd:cd03293 1 LEVRNVSKTYGggggAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRiiaGL--------ERPTSGEVLVDG------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 84 QDIALLRAKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALwNETKDKL-HQsgysLSGGQQQR 161
Cdd:cd03293 66 EPVTGPGPDRGYVFQQDALLPwLTVLDNVALGLEL-QGVPKAEARERAEELLELVGL-SGFENAYpHQ----LSGGMRQR 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 162 LCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDH 221
Cdd:cd03293 140 VALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETgkTVLLVTHDIDEAVFLADR 201
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
11-232 |
1.79e-54 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 175.23 E-value: 1.79e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYG----KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLR--------TfnkmfelypeqraEGEILLDGDN 78
Cdd:COG1136 5 LELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNilggldrpT-------------SGEVLIDGQD 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 79 ILT-NTQDIALLRA-KVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLS 155
Cdd:COG1136 72 ISSlSERELARLRRrHIGFVFQFFNLLPeLTALENVALPLLL-AGVSRKERRERARELLERVGL----GDRLDHRPSQLS 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 156 GGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCsDHTAFMYLGELIE 232
Cdd:COG1136 147 GGQQQRVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELgtTIVMVTHDPELAARA-DRVIRLRDGRIVS 224
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
11-218 |
2.11e-54 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 174.60 E-value: 2.11e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYG----KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNI--LTNTQ 84
Cdd:cd03255 1 IELKNLSKTYGgggeKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGL-----DRPTSGEVRVDGTDIskLSEKE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIALLRAKVGMVFQKPTPFP-MSIYDNIAFGVrLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLC 163
Cdd:cd03255 76 LAAFRRRHIGFVFQSFNLLPdLTALENVELPL-LLAGVPKKERRERAEELLERVGL----GDRLNHYPSELSGGQQQRVA 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARC 218
Cdd:cd03255 151 IARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAgtTIVVVTHDPELAEYA 207
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
11-243 |
2.18e-54 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 175.38 E-value: 2.18e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK----FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEqrAEGEILLDGDNIltNTQDI 86
Cdd:COG1124 2 LEVRNLSVSYGQggrrVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRA---LAGLERP--WSGEVTFDGRPV--TRRRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKPT----PFpMSIYDNIAFGVRLfekLSRADMDERVQWALTKAALWNETKDKL-HQsgysLSGGQQQR 161
Cdd:COG1124 75 KAFRRRVQMVFQDPYaslhPR-HTVDRILAEPLRI---HGLPDREERIAELLEQVGLPPSFLDRYpHQ----LSGGQRQR 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 162 LCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:COG1124 147 VAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERglTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADL 226
|
....
gi 1897751821 240 FTKP 243
Cdd:COG1124 227 LAGP 230
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
11-244 |
3.13e-54 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 177.55 E-value: 3.13e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEQRAEGEILLDGDNILTNTQ-D 85
Cdd:COG0444 2 LEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLP--PPGITSGEILFDGEDLLKLSEkE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IALLRAK-VGMVFQKPT----PFpMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwNETKDKL----HQsgysLSG 156
Cdd:COG0444 80 LRKIRGReIQMIFQDPMtslnPV-MTVGDQIAEPLRIHGGLSKAEARERAIELLERVGL-PDPERRLdrypHE----LSG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 157 GQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFS 234
Cdd:COG0444 154 GMRQRVMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELglAILFITHDLGVVAEIADRVAVMYAGRIVEEG 233
|
250
....*....|
gi 1897751821 235 NTDDLFTKPA 244
Cdd:COG0444 234 PVEELFENPR 243
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
11-252 |
1.81e-53 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 176.04 E-value: 1.81e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILT-NTQD 85
Cdd:COG1135 2 IELENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLL-----ERPTSGSVLVDGVDLTAlSERE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IALLRAKVGMVFQKptpFP-MS---IYDNIAFGVRLfEKLSRADMDERVqwaltkaalwNET------KDKLHQsgY--S 153
Cdd:COG1135 77 LRAARRKIGMIFQH---FNlLSsrtVAENVALPLEI-AGVPKAEIRKRV----------AELlelvglSDKADA--YpsQ 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 154 LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:COG1135 141 LSGGQKQRVGIARALANNPKVLLCDEATSALDPETTRSILDLLKDINRELglTIVLITHEMDVVRRICDRVAVLENGRIV 220
|
250 260
....*....|....*....|.
gi 1897751821 232 EFSNTDDLFTKPAKKQTEDYI 252
Cdd:COG1135 221 EQGPVLDVFANPQSELTRRFL 241
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
11-244 |
1.63e-52 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 172.58 E-value: 1.63e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLN-FYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNILTntQDIALL 89
Cdd:COG1125 2 IEFENVTkRYPDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEP-----TSGRILIDGEDIRD--LDPVEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNET-KDKL-HQsgysLSGGQQQRLCIAR 166
Cdd:COG1125 75 RRRIGYVIQQIGLFPhMTVAENIATVPRL-LGWDKERIRARVDELLELVGLDPEEyRDRYpHE----LSGGQQQRVGVAR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:COG1125 150 ALAADPPILLMDEPFGALDPITREQLQDELLRLQRELgkTIVFVTHDIDEALKLGDRIAVMREGRIVQYDTPEEILANPA 229
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
26-182 |
1.72e-52 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 167.44 E-value: 1.72e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIltNTQDIALLRAKVGMVFQKPTPFP- 104
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGL-----LSPTEGTILLDGQDL--TDDERKSLRKEIGYVFQDPQLFPr 73
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 105 MSIYDNIAFGVRLFEkLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCS 182
Cdd:pfam00005 74 LTVRENLRLGLLLKG-LSKREKDARAEEALEKLGLGDLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
11-244 |
2.58e-52 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 169.72 E-value: 2.58e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRT---FnkmfelypEQRAEGEILLDGDNILtntqDIA 87
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLiagF--------ETPTSGEILLDGKDIT----NLP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIAR 166
Cdd:cd03300 69 PHKRPVNTVFQNYALFPhLTVFENIAFGLRL-KKLPKAEIKERVAEALDLVQLEGYANRKPSQ----LSGGQQQRVAIAR 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPistgRI-EELITELKE-----DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLF 240
Cdd:cd03300 144 ALVNEPKVLLLDEPLGALDL----KLrKDMQLELKRlqkelGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIY 219
|
....
gi 1897751821 241 TKPA 244
Cdd:cd03300 220 EEPA 223
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
11-225 |
3.32e-52 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 167.17 E-value: 3.32e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYG--KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGDNIltNTQDIAL 88
Cdd:cd03228 1 IEFKNVSFSYPgrPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPT-----SGEILIDGVDL--RDLDLES 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKVGMVFQKPTPFPMSIYDNIafgvrlfeklsradmdervqwaltkaalwnetkdklhqsgysLSGGQQQRLCIARGI 168
Cdd:cd03228 74 LRKNIAYVPQDPFLFSGTIRENI------------------------------------------LSGGQRQRIAIARAL 111
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHTAFM 225
Cdd:cd03228 112 LRDPPILILDEATSALDPETEALILEALRALAKGKTVIVIAHRLSTIRDA-DRIIVL 167
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
11-252 |
9.27e-52 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 168.73 E-value: 9.27e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILTNTQDIALLR 90
Cdd:PRK09493 2 IEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKL-----EEITSGDLIVDGLKVNDPKVDERLIR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIA 169
Cdd:PRK09493 77 QEAGMVFQQFYLFPhLTALENVMFGPLRVRGASKEEAEKQARELLAKVGL----AERAHHYPSELSGGQQQRVAIARALA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQT 248
Cdd:PRK09493 153 VKPKLMLFDEPTSALDPELRHEVLKVMQDLAEEgMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRL 232
|
....
gi 1897751821 249 EDYI 252
Cdd:PRK09493 233 QEFL 236
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
9-239 |
1.18e-51 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 178.87 E-value: 1.18e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYYGKFH--ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQraEGEILLDGDNIltNTQDI 86
Cdd:COG2274 472 GDIELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKL---LLGLYEPT--SGRILIDGIDL--RQIDP 544
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKPTPFPMSIYDNIAFGvrlfekLSRADmDERVQWALTKAALWNETKD-------KLHQSGYSLSGGQQ 159
Cdd:COG2274 545 ASLRRQIGVVLQDVFLFSGTIRENITLG------DPDAT-DEEIIEAARLAGLHDFIEAlpmgydtVVGEGGSNLSGGQR 617
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHTAFMYLGELIEFSNTDDL 239
Cdd:COG2274 618 QRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAHRLSTIRLA-DRIIVLDKGRIVEDGTHEEL 696
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
11-241 |
2.92e-50 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 164.88 E-value: 2.92e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPeqRAEGEILLDGdniltntQDIALLR 90
Cdd:COG1121 7 IELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKA---ILGLLP--PTSGTVRLFG-------KPPRRAR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPT---PFPMSIYDNIAFG----VRLFEKLSRADmDERVQWALTKAALWnetkDKLHQSGYSLSGGQQQRLC 163
Cdd:COG1121 75 RRIGYVPQRAEvdwDFPITVRDVVLMGrygrRGLFRRPSRAD-REAVDEALERVGLE----DLADRPIGELSGGQQQRVL 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMyLGELIEFSNTDDLFT 241
Cdd:COG1121 150 LARALAQDPDLLLLDEPFAGVDAATEEALYELLRELrREGKTILVVTHDLGAVREYFDRVLLL-NRGLVAHGPPEEVLT 227
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
11-243 |
3.02e-50 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 164.29 E-value: 3.02e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYG----KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIlTNTQDI 86
Cdd:cd03258 2 IELKNVSKVFGdtggKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGL-----ERPTSGSVLVDGTDL-TLLSGK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 AL--LRAKVGMVFQKptpFPM----SIYDNIAFGVRLfEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQ 160
Cdd:cd03258 76 ELrkARRRIGMIFQH---FNLlssrTVFENVALPLEI-AGVPKAEIEERVLELLELVGL----EDKADAYPAQLSGGQKQ 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 161 RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDD 238
Cdd:cd03258 148 RVGIARALANNPKVLLCDEATSALDPETTQSILALLRDInrELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEE 227
|
....*
gi 1897751821 239 LFTKP 243
Cdd:cd03258 228 VFANP 232
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
4-210 |
3.06e-50 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 173.04 E-value: 3.06e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 4 VDTAPGKIQVRDLNFYYGKFH-ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEqraEGEILLDGDNIltn 82
Cdd:COG1132 333 LPPVRGEIEFENVSFSYPGDRpVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYD--PT---SGRILIDGVDI--- 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 83 tQDIAL--LRAKVGMVFQKPTPFPMSIYDNIAFGvrlfeklsRADM-DERVQWALTKAALW---NETKDKLH----QSGY 152
Cdd:COG1132 405 -RDLTLesLRRQIGVVPQDTFLFSGTIRENIRYG--------RPDAtDEEVEEAAKAAQAHefiEALPDGYDtvvgERGV 475
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 153 SLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTH 210
Cdd:COG1132 476 NLSGGQRQRIAIARALLKDPPILILDEATSALDTETEALIQEALERLMKGRTTIVIAH 533
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
11-252 |
6.36e-50 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 164.03 E-value: 6.36e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNI----LTNTQDI 86
Cdd:COG4161 3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLL-----ETPDSGQLNIAGHQFdfsqKPSEKAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKPTPFP-MSIYDN-IAFGVRLFeKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCI 164
Cdd:COG4161 78 RLLRQKVGMVFQQYNLWPhLTVMENlIEAPCKVL-GLSKEQAREKAMKLLARLRL----TDKADRFPLHLSGGQQQRVAI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 165 ARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSnTDDLFTKP 243
Cdd:COG4161 153 ARALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQtGITQVIVTHEVEFARKVASQVVYMEKGRIIEQG-DASHFTQP 231
|
....*....
gi 1897751821 244 AKKQTEDYI 252
Cdd:COG4161 232 QTEAFAHYL 240
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
11-253 |
1.47e-49 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 162.88 E-value: 1.47e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNI----LTNTQDI 86
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLL-----EMPRSGTLNIAGNHFdfskTPSDKAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKPTPFP-MSIYDN-IAFGVRLFeKLSRADMDERVQWALTKAALwNETKDK--LHqsgysLSGGQQQRL 162
Cdd:PRK11124 78 RELRRNVGMVFQQYNLWPhLTVQQNlIEAPCRVL-GLSKDQALARAEKLLERLRL-KPYADRfpLH-----LSGGQQQRV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 163 CIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEfSNTDDLFT 241
Cdd:PRK11124 151 AIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAETgITQVIVTHEVEVARKTASRVVYMENGHIVE-QGDASCFT 229
|
250
....*....|..
gi 1897751821 242 KPAKKQTEDYIT 253
Cdd:PRK11124 230 QPQTEAFKNYLS 241
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
11-239 |
3.33e-49 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 162.98 E-value: 3.33e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGDNILT--NTQDI 86
Cdd:TIGR04520 1 IEVENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGL--LLPT---SGKVTVDGLDTLDeeNLWEI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 allRAKVGMVFQKPtpfpmsiyDN----------IAFGVrlfE--KLSRADMDERVQWALTKAALWnetkDKLHQSGYSL 154
Cdd:TIGR04520 76 ---RKKVGMVFQNP--------DNqfvgatveddVAFGL---EnlGVPREEMRKRVDEALKLVGME----DFRDREPHLL 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 155 SGGQQQRLCIARGIAIRPEVLLLDEPCSALDPIstGRIE--ELITELKEDY--TVVIVTHNMQQAARcSDHTAFMYLGEL 230
Cdd:TIGR04520 138 SGGQKQRVAIAGVLAMRPDIIILDEATSMLDPK--GRKEvlETIRKLNKEEgiTVISITHDMEEAVL-ADRVIVMNKGKI 214
|
250
....*....|....*.
gi 1897751821 231 IE-------FSNTDDL 239
Cdd:TIGR04520 215 VAegtpreiFSQVELL 230
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
11-220 |
5.09e-48 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 159.07 E-value: 5.09e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNF-YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNILT-NTQDIAL 88
Cdd:COG3638 3 LELRNLSKrYPGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGL--VEP---TSGEILVDGQDVTAlRGRALRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKVGMVFQKptpFP----MSIYDNIAFGvRL---------FEKLSRADMdERVQWALTKAALwnetKDKLHQSGYSLS 155
Cdd:COG3638 78 LRRRIGMIFQQ---FNlvprLSVLTNVLAG-RLgrtstwrslLGLFPPEDR-ERALEALERVGL----ADKAYQRADQLS 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 156 GGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSD 220
Cdd:COG3638 149 GGQQQRVAIARALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDgiTVVVNLHQVDLARRYAD 215
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
5-239 |
6.55e-48 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 166.47 E-value: 6.55e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 5 DTAPGKIQVRDLNFYY-GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGDNIltNT 83
Cdd:COG4988 331 AAGPPSIELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPY-----SGSILINGVDL--SD 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 84 QDIALLRAKVGMVFQKPTPFPMSIYDNIAFGVRlfeklsRADmDERVQWALTKAALWNETKD-------KLHQSGYSLSG 156
Cdd:COG4988 404 LDPASWRRQIAWVPQNPYLFAGTIRENLRLGRP------DAS-DEELEAALEAAGLDEFVAAlpdgldtPLGEGGRGLSG 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 157 GQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHTAFMYLGELIEFSNT 236
Cdd:COG4988 477 GQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAKGRTVILITHRLALLAQA-DRILVLDDGRIVEQGTH 555
|
...
gi 1897751821 237 DDL 239
Cdd:COG4988 556 EEL 558
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
11-252 |
1.10e-47 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 158.10 E-value: 1.10e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGDNIltnTQDIALLR 90
Cdd:COG4555 2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGL--LKPD---SGSILIDGEDV---RKEPREAR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPtPFP--MSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALWNETKDKLHqsgySLSGGQQQRLCIARGI 168
Cdd:COG4555 74 RQIGVLPDER-GLYdrLTVRENIRYFAELY-GLFDEELKKRIEELIELLGLEEFLDRRVG----ELSTGMKKKVALARAL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQ 247
Cdd:COG4555 148 VHDPKVLLLDEPTNGLDVMARRLLREILRALKkEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEEN 227
|
....*
gi 1897751821 248 TEDYI 252
Cdd:COG4555 228 LEDAF 232
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
11-213 |
1.34e-47 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 157.14 E-value: 1.34e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFH-ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkmfeLYPEQRA-EGEILLDGDNILT-NTQDIA 87
Cdd:COG2884 2 IRFENVSKRYPGGReALSDVSLEIEKGEFVFLTGPSGAGKSTLLKL------LYGEERPtSGQVLVNGQDLSRlKRREIP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKptpFP----MSIYDNIAFGVRLFEKlSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLC 163
Cdd:COG2884 76 YLRRRIGVVFQD---FRllpdRTVYENVALPLRVTGK-SRKEIRRRVREVLDLVGL----SDKAKALPHELSGGEQQRVA 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQ 213
Cdd:COG2884 148 IARALVNRPELLLADEPTGNLDPETSWEIMELLEEInRRGTTVLIATHDLE 198
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
3-243 |
1.44e-47 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 158.43 E-value: 1.44e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 3 MVDTAPGKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILT- 81
Cdd:COG4598 1 MTDTAPPALEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLL-----ETPDSGEIRVGGEEIRLk 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 82 ----------NTQDIALLRAKVGMVFQKptpFP----MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWnetkDKL 147
Cdd:COG4598 76 pdrdgelvpaDRRQLQRIRTRLGMVFQS---FNlwshMTVLENVIEAPVHVLGRPKAEAIERAEALLAKVGLA----DKR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 148 HQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPistgrieELITE-LK-------EDYTVVIVTHNMQQAARCS 219
Cdd:COG4598 149 DAYPAHLSGGQQQRAAIARALAMEPEVMLFDEPTSALDP-------ELVGEvLKvmrdlaeEGRTMLVVTHEMGFARDVS 221
|
250 260
....*....|....*....|....
gi 1897751821 220 DHTAFMYLGELIEFSNTDDLFTKP 243
Cdd:COG4598 222 SHVVFLHQGRIEEQGPPAEVFGNP 245
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
11-229 |
2.07e-47 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 156.83 E-value: 2.07e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPeqRAEGEILLDGDNIlTNTQDIALLR 90
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKT---IMGLLP--PRSGSIRFDGRDI-TGLPPHERAR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLfekLSRADMDERVQWALtkaALWNETKDKLHQSGYSLSGGQQQRLCIARGIA 169
Cdd:cd03224 75 AGIGYVPEGRRIFPeLTVEENLLLGAYA---RRRAKRKARLERVY---ELFPRLKERRKQLAGTLSGGEQQMLAIARALM 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTHNMQQAARCSDHTAFMYLGE 229
Cdd:cd03224 149 SRPKLLLLDEPSEGLAPKIVEEIFEAIRELRdEGVTILLVEQNARFALEIADRAYVLERGR 209
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
25-254 |
3.94e-47 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 157.42 E-value: 3.94e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPeqrAEGEILLDGDNI--LTNTQDIALLRAKVGMVFQKPTP 102
Cdd:cd03294 39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIE--P---TSGKVLIDGQDIaaMSRKELRELRRKKISMVFQSFAL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 103 FP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPC 181
Cdd:cd03294 114 LPhRTVLENVAFGLEV-QGVPRAEREERAAEALELVGL----EGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAF 188
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 182 SALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITG 254
Cdd:cd03294 189 SALDPLIRREMQDELLRLqaELQKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREFFRG 263
|
|
| proV |
TIGR01186 |
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ... |
25-254 |
4.15e-47 |
|
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 160.40 E-value: 4.15e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqRAEGEILLDGDNIlTNTQDIALL---RAKVGMVFQKPT 101
Cdd:TIGR01186 8 GVNDADLAIAKGEIFVIMGLSGSGKSTTVRMLNRLIE-----PTAGQIFIDGENI-MKQSPVELRevrRKKIGMVFQQFA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 102 PFP-MSIYDNIAFGVrlfeKLSRADMDERVQWALTKAALWNeTKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEP 180
Cdd:TIGR01186 82 LFPhMTILQNTSLGP----ELLGWPEQERKEKALELLKLVG-LEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEA 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 181 CSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITG 254
Cdd:TIGR01186 157 FSALDPLIRDSMQDELKKLQATLqkTIVFITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGK 232
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
11-231 |
9.07e-47 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 155.67 E-value: 9.07e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLlrtFNKMFELYPeqRAEGEILLDGDNIlTNTQDIALLR 90
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTL---FNLISGFLR--PTSGSVLFDGEDI-TGLPPHEIAR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLS---------RADMDERVQWALTKAALWnetkDKLHQSGYSLSGGQQQ 160
Cdd:cd03219 75 LGIGRTFQIPRLFPeLTVLENVMVAAQARTGSGlllararreEREARERAEELLERVGLA----DLADRPAGELSYGQQR 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 161 RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:cd03219 151 RLEIARALATDPKLLLLDEPAAGLNPEETEELAELIRELRErGITVLLVEHDMDVVMSLADRVTVLDQGRVI 222
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
12-229 |
1.04e-46 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 152.78 E-value: 1.04e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPeqrAEGEILLDGDNILTNtqDIALLRA 91
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAI--AGLLKP---TSGEILIDGKDIAKL--PLEELRR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 92 KVGMVFQkptpfpmsiydniafgvrlfeklsradmdervqwaltkaalwnetkdklhqsgysLSGGQQQRLCIARGIAIR 171
Cdd:cd00267 74 RIGYVPQ-------------------------------------------------------LSGGQRQRVALARALLLN 98
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 172 PEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGE 229
Cdd:cd00267 99 PDLLLLDEPTSGLDPASRERLLELLRELaEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
11-230 |
2.64e-46 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 152.17 E-value: 2.64e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGDNILTNTQDIallR 90
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPD-----SGEIKVLGKDIKKEPEEV---K 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIafgvrlfeklsradmdervqwaltkaalwnetkdklhqsgySLSGGQQQRLCIARGIA 169
Cdd:cd03230 73 RRIGYLPEEPSLYEnLTVRENL-----------------------------------------KLSGGMKQRLALAQALL 111
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGEL 230
Cdd:cd03230 112 HDPELLILDEPTSGLDPESRREFWELLRELkKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
11-252 |
5.58e-46 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 156.50 E-value: 5.58e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILT-NTQD 85
Cdd:PRK11153 2 IELKNISKVFpqggRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLL-----ERPTSGRVLVDGQDLTAlSEKE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IALLRAKVGMVFQKptpFPM----SIYDNIAFGVRLfEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQR 161
Cdd:PRK11153 77 LRKARRQIGMIFQH---FNLlssrTVFDNVALPLEL-AGTPKAEIKARVTELLELVGL----SDKADRYPAQLSGGQKQR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 162 LCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:PRK11153 149 VAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRELglTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEV 228
|
250
....*....|...
gi 1897751821 240 FTKPAKKQTEDYI 252
Cdd:PRK11153 229 FSHPKHPLTREFI 241
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
11-244 |
3.32e-45 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 151.72 E-value: 3.32e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIltntQDIALLR 90
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGL-----ERPDSGTILFGGEDA----TDVPVQE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRL---FEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIAR 166
Cdd:cd03296 74 RNVGFVFQHYALFRhMTVFDNVAFGLRVkprSERPPEAEIRAKVHELLKLVQLDWLADRYPAQ----LSGGQRQRVALAR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPISTGRIEELITELKED--YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:cd03296 150 ALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDElhVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPA 229
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
11-230 |
1.02e-44 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 149.71 E-value: 1.02e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGdniltntQDIALLR 90
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGL-----EEPTSGRIYIGG-------RDVTDLP 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AK---VGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIAR 166
Cdd:cd03301 69 PKdrdIAMVFQNYALYPhMTVYDNIAFGLKL-RKVPKDEIDERVREVAELLQIEHLLDRKPKQ----LSGGQRQRVALGR 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 167 GIAIRPEVLLLDEPCSALDpiSTGRIeELITELKE-----DYTVVIVTHNMQQAARCSDHTAFMYLGEL 230
Cdd:cd03301 144 AIVREPKVFLMDEPLSNLD--AKLRV-QMRAELKRlqqrlGTTTIYVTHDQVEAMTMADRIAVMNDGQI 209
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
11-252 |
1.90e-44 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 149.79 E-value: 1.90e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHaLKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEQraeGEILLDGDNIlTNTQDIallR 90
Cdd:cd03299 1 LKVENLSKDWKEFK-LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIK--PDS---GKILLNGKDI-TNLPPE---K 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVqwaLTKAALWNETKdKLHQSGYSLSGGQQQRLCIARGIA 169
Cdd:cd03299 71 RDISYVPQNYALFPhMTVYKNIAYGLKK-RKVDKKEIERKV---LEIAEMLGIDH-LLNRKPETLSGGEQQRVAIARALV 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQ 247
Cdd:cd03299 146 VNPKILLLDEPFSALDVRTKEKLREELKKIRKEFgvTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEF 225
|
....*
gi 1897751821 248 TEDYI 252
Cdd:cd03299 226 VAEFL 230
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
11-252 |
3.43e-44 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 152.50 E-value: 3.43e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGdniltntQDIALL- 89
Cdd:TIGR03265 5 LSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGL-----ERQTAGTIYQGG-------RDITRLp 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 --RAKVGMVFQKPTPFP-MSIYDNIAFGVRlFEKLSRADMDERVQWALTKAALWNeTKDKlhqsgY--SLSGGQQQRLCI 164
Cdd:TIGR03265 73 pqKRDYGIVFQSYALFPnLTVADNIAYGLK-NRGMGRAEVAERVAELLDLVGLPG-SERK-----YpgQLSGGQQQRVAL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 165 ARGIAIRPEVLLLDEPCSALDpistGRI-EELITELKE-----DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDD 238
Cdd:TIGR03265 146 ARALATSPGLLLLDEPLSALD----ARVrEHLRTEIRQlqrrlGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQE 221
|
250
....*....|....
gi 1897751821 239 LFTKPAKKQTEDYI 252
Cdd:TIGR03265 222 IYRHPATPFVADFV 235
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
12-223 |
1.87e-43 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 146.52 E-value: 1.87e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPeqRAEGEILLDGdniltntQDIALLRA 91
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKA---ILGLLK--PTSGSIRVFG-------KPLEKERK 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 92 KVGMVFQK---PTPFPMSIYDNIAFG----VRLFEKLSRADMdERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCI 164
Cdd:cd03235 69 RIGYVPQRrsiDRDFPISVRDVVLMGlyghKGLFRRLSKADK-AKVDEALERVGL----SELADRQIGELSGGQQQRVLL 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 165 ARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTA 223
Cdd:cd03235 144 ARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRREgMTILVVTHDLGLVLEYFDRVL 203
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-252 |
5.74e-43 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 146.43 E-value: 5.74e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 1 MSMvdtapgkIQVRDLNfyyGKFHA---LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGD 77
Cdd:PRK11264 1 MSA-------IEVKNLV---KKFHGqtvLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 78 NILTNTQD-IALLRAKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNEtkdklhQSGY--S 153
Cdd:PRK11264 71 RSLSQQKGlIRQLRQHVGFVFQNFNLFPhRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGK------ETSYprR 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 154 LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIE 232
Cdd:PRK11264 145 LSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLaQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVE 224
|
250 260
....*....|....*....|
gi 1897751821 233 FSNTDDLFTKPAKKQTEDYI 252
Cdd:PRK11264 225 QGPAKALFADPQQPRTRQFL 244
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
7-254 |
9.03e-43 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 145.88 E-value: 9.03e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 7 APGKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNkmfelYPEQRAEGEILLDGDNI------- 79
Cdd:PRK10619 2 SENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCIN-----FLEKPSEGSIVVNGQTInlvrdkd 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 80 ----LTNTQDIALLRAKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwnetkDKLHQSGY-- 152
Cdd:PRK10619 77 gqlkVADKNQLRLLRTRLTMVFQHFNLWShMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGI-----DERAQGKYpv 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 153 SLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:PRK10619 152 HLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEgKTMVVVTHEMGFARHVSSHVIFLHQGKIE 231
|
250 260
....*....|....*....|...
gi 1897751821 232 EFSNTDDLFTKPAKKQTEDYITG 254
Cdd:PRK10619 232 EEGAPEQLFGNPQSPRLQQFLKG 254
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
11-252 |
1.06e-42 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 149.22 E-value: 1.06e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGdniltntQDIALL- 89
Cdd:PRK11607 20 LEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGF-----EQPTAGQIMLDG-------VDLSHVp 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 --RAKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIAR 166
Cdd:PRK11607 88 pyQRPINMMFQSYALFPhMTVEQNIAFGLKQ-DKLPKAEIASRVNEMLGLVHMQEFAKRKPHQ----LSGGQRQRVALAR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPISTGRIEELITELKE--DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:PRK11607 163 SLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILErvGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPT 242
|
....*...
gi 1897751821 245 KKQTEDYI 252
Cdd:PRK11607 243 TRYSAEFI 250
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
7-232 |
1.46e-42 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 152.23 E-value: 1.46e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 7 APGKIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEQraeGEILLDGDNIltNTQ 84
Cdd:COG4987 330 GGPSLELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLD--PQS---GSITLGGVDL--RDL 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIALLRAKVGMVFQKPTPFPMSIYDNIAFGvrlfekLSRADmDERVQWALTKAAL--WNETKDK-----LHQSGYSLSGG 157
Cdd:COG4987 403 DEDDLRRRIAVVPQRPHLFDTTLRENLRLA------RPDAT-DEELWAALERVGLgdWLAALPDgldtwLGEGGRRLSGG 475
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 158 QQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHTAFMYLGELIE 232
Cdd:COG4987 476 ERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGRTVLLITHRLAGLERM-DRILVLEDGRIVE 549
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
11-252 |
1.70e-42 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 144.51 E-value: 1.70e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHalKNINLDIAKNQVTAFIGPSGCGKSTLLRT---FnkmfelypEQRAEGEILLDGDNILtnTQDIA 87
Cdd:COG3840 2 LRLDDLTYRYGDFP--LRFDLTIAAGERVAILGPSGAGKSTLLNLiagF--------LPPDSGRILWNGQDLT--ALPPA 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 llRAKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMdERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIAR 166
Cdd:COG3840 70 --ERPVSMLFQENNLFPhLTVAQNIGLGLRPGLKLTAEQR-AQVEQALERVGL----AGLLDRLPGQLSGGQRQRVALAR 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 167 giAI---RPeVLLLDEPCSALDPIStgRIE--ELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:COG3840 143 --CLvrkRP-ILLLDEPFSALDPAL--RQEmlDLVDELCRERglTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAAL 217
|
250
....*....|...
gi 1897751821 240 FTKPAKKQTEDYI 252
Cdd:COG3840 218 LDGEPPPALAAYL 230
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
11-239 |
1.92e-42 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 144.60 E-value: 1.92e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY---GKFHALKNINLDIAKNQVTAFIGPSGCGKST----LLRTFNkmfelyPEqraEGEILLDGDNIltNT 83
Cdd:cd03249 1 IEFKNVSFRYpsrPDVPILKGLSLTIPPGKTVALVGSSGCGKSTvvslLERFYD------PT---SGEILLDGVDI--RD 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 84 QDIALLRAKVGMVFQKPTPFPMSIYDNIAFGvrlfekLSRADMDERVQwALTKAALWN---ETKDKLH----QSGYSLSG 156
Cdd:cd03249 70 LNLRWLRSQIGLVSQEPVLFDGTIAENIRYG------KPDATDEEVEE-AAKKANIHDfimSLPDGYDtlvgERGSQLSG 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 157 GQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMqQAARCSDHTAFMYLGELIEFSNT 236
Cdd:cd03249 143 GQKQRIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMKGRTTIVIAHRL-STIRNADLIAVLQNGQVVEQGTH 221
|
...
gi 1897751821 237 DDL 239
Cdd:cd03249 222 DEL 224
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
11-244 |
5.78e-42 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 146.03 E-value: 5.78e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY-----------GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPeqrAEGEILLDGDNI 79
Cdd:COG4608 8 LEVRDLKKHFpvrgglfgrtvGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEE--P---TSGEILFDGQDI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 80 LT-NTQDIALLRAKVGMVFQKPtpF----P-MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKL-HQsgy 152
Cdd:COG4608 83 TGlSGRELRPLRRRMQMVFQDP--YaslnPrMTVGDIIAEPLRIHGLASKAERRERVAELLELVGLRPEHADRYpHE--- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 153 sLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDpIStgrIE----ELITELKEDY--TVVIVTHNMQQAARCSDHTAFMY 226
Cdd:COG4608 158 -FSGGQRQRIGIARALALNPKLIVCDEPVSALD-VS---IQaqvlNLLEDLQDELglTYLFISHDLSVVRHISDRVAVMY 232
|
250
....*....|....*...
gi 1897751821 227 LGELIEFSNTDDLFTKPA 244
Cdd:COG4608 233 LGKIVEIAPRDELYARPL 250
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
12-247 |
1.26e-41 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 142.43 E-value: 1.26e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPeqRAEGEILLDGDNIlTN--TQDIAll 89
Cdd:COG0410 5 EVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKA---ISGLLP--PRSGSIRFDGEDI-TGlpPHRIA-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVfqkptP-----FP-MSIYDNIAFGVRLfeKLSRADMDERVQWALtkaALWNETKDKLHQSGYSLSGGQQQRLC 163
Cdd:COG0410 77 RLGIGYV-----PegrriFPsLTVEENLLLGAYA--RRDRAEVRADLERVY---ELFPRLKERRRQRAGTLSGGEQQMLA 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:COG0410 147 IGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNREgVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLAD 226
|
....*
gi 1897751821 243 PAKKQ 247
Cdd:COG0410 227 PEVRE 231
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
10-232 |
2.63e-41 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 142.85 E-value: 2.63e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 10 KIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQraeGEILLDGdnILTNTQDIA 87
Cdd:PRK13635 5 IIRVEHISFRYpdAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGL--LLPEA---GTITVGG--MVLSEETVW 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKP-TPF-PMSIYDNIAFGVrlfEK--LSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLC 163
Cdd:PRK13635 78 DVRRQVGMVFQNPdNQFvGATVQDDVAFGL---ENigVPREEMVERVDQALRQVGM----EDFLNREPHRLSGGQKQRVA 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPIstGRIE--ELITELKE--DYTVVIVTHNMQQAARcSDHTAFMYLGELIE 232
Cdd:PRK13635 151 IAGVLALQPDIIILDEATSMLDPR--GRREvlETVRQLKEqkGITVLSITHDLDEAAQ-ADRVIVMNKGEILE 220
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
11-242 |
3.37e-41 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 142.68 E-value: 3.37e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK-FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNILTNTQDIALL 89
Cdd:PRK13636 6 LKVEELNYNYSDgTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGI--LKP---SSGRILFDGKPIDYSRKGLMKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTP--FPMSIYDNIAFGVrLFEKLSRADMDERVQWALTKAALwNETKDKlhqSGYSLSGGQQQRLCIARG 167
Cdd:PRK13636 81 RESVGMVFQDPDNqlFSASVYQDVSFGA-VNLKLPEDEVRKRVDNALKRTGI-EHLKDK---PTHCLSFGQKKRVAIAGV 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITELKE--DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:PRK13636 156 LVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKelGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAE 232
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
12-231 |
5.16e-41 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 139.11 E-value: 5.16e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNILT-NTQDIALLR 90
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKP-----SSGEILLDGKDLASlSPKELARKI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVfqkptpfpmsiydniafgvrlfekLSRADMDervqwaltkaalwnetkDKLHQSGYSLSGGQQQRLCIARGIAI 170
Cdd:cd03214 76 AYVPQA------------------------LELLGLA-----------------HLADRPFNELSGGERQRVLLARALAQ 114
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 171 RPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:cd03214 115 EPPILLLDEPTSHLDIAHQIELLELLRRLARERgkTVVMVLHDLNLAARYADRVILLKDGRIV 177
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
11-225 |
5.20e-41 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 144.70 E-value: 5.20e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGdniltntQDIALLR 90
Cdd:PRK09452 15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGF-----ETPDSGRIMLDG-------QDITHVP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AK---VGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIAR 166
Cdd:PRK09452 83 AEnrhVNTVFQSYALFPhMTVFENVAFGLRM-QKTPAAEITPRVMEALRMVQLEEFAQRKPHQ----LSGGQQQRVAIAR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 167 GIAIRPEVLLLDEPCSALDpiSTGRiEELITELKE-----DYTVVIVTHNMQQAARCSDHTAFM 225
Cdd:PRK09452 158 AVVNKPKVLLLDESLSALD--YKLR-KQMQNELKAlqrklGITFVFVTHDQEEALTMSDRIVVM 218
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
11-231 |
5.60e-41 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 140.33 E-value: 5.60e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK--FHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfnKMfeLYPEQRA-EGEILLDGDNILTNTQDIa 87
Cdd:cd03263 1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTL----KM--LTGELRPtSGTAYINGYSIRTDRKAA- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 llRAKVGMVFQKPTPFP-MSIYDNIAFGVRLfeK-LSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIA 165
Cdd:cd03263 74 --RQSLGYCPQFDALFDeLTVREHLRFYARL--KgLPKSEIKEEVELLLRVLGL----TDKANKRARTLSGGMKRKLSLA 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 166 RGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:cd03263 146 IALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDRIAIMSDGKLR 211
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
11-240 |
8.45e-41 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 141.72 E-value: 8.45e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK---FH--ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNILTNTQD 85
Cdd:PRK13637 3 IKIENLTHIYMEgtpFEkkALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGL--LKP---TSGKIIIDGVDITDKKVK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IALLRAKVGMVFQKP--TPFPMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAAL-WNETKDKlhqSGYSLSGGQQQRL 162
Cdd:PRK13637 78 LSDIRKKVGLVFQYPeyQLFEETIEKDIAFGPINL-GLSEEEIENRVKRAMNIVGLdYEDYKDK---SPFELSGGQKRRV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 163 CIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLF 240
Cdd:PRK13637 154 AIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYnmTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVF 233
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
9-242 |
1.14e-40 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 139.67 E-value: 1.14e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY-GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfeLYPEQraEGEILLDGDNIltNTQDIA 87
Cdd:cd03254 1 GEIEFENVNFSYdEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMR---FYDPQ--KGQILIDGIDI--RDISRK 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKPTPFPMSIYDNIAFGVrlfeklSRADMDERVQWALTKAA------LWNETKDKLHQSGYSLSGGQQQR 161
Cdd:cd03254 74 SLRSMIGVVLQDTFLFSGTIMENIRLGR------PNATDEEVIEAAKEAGAhdfimkLPNGYDTVLGENGGNLSQGERQL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 162 LCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMqQAARCSDHTAFMYLGELIEFSNTDDLFT 241
Cdd:cd03254 148 LAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGRTSIIIAHRL-STIKNADKILVLDDGKIIEEGTHDELLA 226
|
.
gi 1897751821 242 K 242
Cdd:cd03254 227 K 227
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
42-244 |
2.32e-40 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 141.48 E-value: 2.32e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 42 IGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIltnTQDIALLRAkVGMVFQKPTPFP-MSIYDNIAFGVRLfEK 120
Cdd:TIGR01187 2 LGPSGCGKTTLLRLLAGF-----EQPDSGSIMLDGEDV---TNVPPHLRH-INMVFQSYALFPhMTVEENVAFGLKM-RK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 121 LSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIE-ELITEL 199
Cdd:TIGR01187 72 VPRAEIKPRVLEALRLVQLEEFADRKPHQ----LSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQlELKTIQ 147
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1897751821 200 KE-DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:TIGR01187 148 EQlGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPA 193
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
19-221 |
5.00e-40 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 138.47 E-value: 5.00e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNIlTNTQDIAL--LRAKVGMV 96
Cdd:cd03256 10 YPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEP-----TSGSVLIDGTDI-NKLKGKALrqLRRQIGMI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 97 FQKPTPFP-MSIYDNIAFG-------VR-LFEKLSRADMdERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARG 167
Cdd:cd03256 84 FQQFNLIErLSVLENVLSGrlgrrstWRsLFGLFPKEEK-QRALAALERVGL----LDKAYQRADQLSGGQQQRVAIARA 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDH 221
Cdd:cd03256 159 LMQQPKLILADEPVASLDPASSRQVMDLLKRInrEEGITVIVSLHQVDLAREYADR 214
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
12-231 |
5.24e-40 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 138.63 E-value: 5.24e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLlrtFNKMFELYPEQraEGEILLDGdniltntQDIALL-- 89
Cdd:COG0411 6 EVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTL---FNLITGFYRPT--SGRILFDG-------RDITGLpp 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 --RAKVGMV--FQKPTPFP-MSIYDNIAFGV------RLFEKLSR--------ADMDERVQWALTKAALwnetKDKLHQS 150
Cdd:COG0411 74 hrIARLGIArtFQNPRLFPeLTVLENVLVAAharlgrGLLAALLRlprarreeREARERAEELLERVGL----ADRADEP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 151 GYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED--YTVVIVTHNMQQAARCSDHTAFMYLG 228
Cdd:COG0411 150 AGNLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDErgITILLIEHDMDLVMGLADRIVVLDFG 229
|
...
gi 1897751821 229 ELI 231
Cdd:COG0411 230 RVI 232
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
11-257 |
5.13e-39 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 135.89 E-value: 5.13e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFH-ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNIlTNTQ--DIA 87
Cdd:TIGR02315 2 LEVENLSKVYPNGKqALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEP-----SSGSILLEGTDI-TKLRgkKLR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKPTPFP-MSIYDNIAFGvRL---------FEKLSRADMdERVQWALTKAALwnetKDKLHQSGYSLSGG 157
Cdd:TIGR02315 76 KLRRRIGMIFQHYNLIErLTVLENVLHG-RLgykptwrslLGRFSEEDK-ERALSALERVGL----ADKAYQRADQLSGG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 158 QQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL-KED-YTVVIVTHNMQQAARCSDHTAFMYLGELIefsn 235
Cdd:TIGR02315 150 QQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRInKEDgITVIINLHQVDLAKKYADRIVGLKAGEIV---- 225
|
250 260
....*....|....*....|..
gi 1897751821 236 tddlFTKPAKKQTEDYITGRYG 257
Cdd:TIGR02315 226 ----FDGAPSELDDEVLRHIYG 243
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
11-243 |
1.03e-38 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 135.98 E-value: 1.03e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK-FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEqraEGEILLDGDNILTNTQDIALL 89
Cdd:PRK13639 2 LETRDLKYSYPDgTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILK--PT---SGEVLIKGEPIKYDKKSLLEV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTP--FPMSIYDNIAFGvRLFEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARG 167
Cdd:PRK13639 77 RKTVGIVFQNPDDqlFAPTVEEDVAFG-PLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHH----LSGGQKKRVAIAGI 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKP 243
Cdd:PRK13639 152 LAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLnKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDI 228
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
19-217 |
2.04e-38 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 133.53 E-value: 2.04e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILTNT-QDIALLRAKVGMVF 97
Cdd:TIGR02673 11 YPGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGA-----LTPSRGQVRIAGEDVNRLRgRQLPLLRRRIGVVF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 98 QKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLL 176
Cdd:TIGR02673 86 QDFRLLPdRTVYENVALPLEV-RGKKEREIQRRVGAALRQVGL----EHKADAFPEQLSGGEQQRVAIARAIVNSPPLLL 160
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1897751821 177 LDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAAR 217
Cdd:TIGR02673 161 ADEPTGNLDPDLSERILDLLKRLnKRGTTVIVATHDLSLVDR 202
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
25-245 |
2.09e-38 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 135.53 E-value: 2.09e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFelypeQRAEGEILLdGDNILTNT---QDIALLRAKVGMVFQKPT 101
Cdd:PRK13634 22 ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLL-----QPTSGTVTI-GERVITAGkknKKLKPLRKKVGIVFQFPE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 102 P--FPMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALwneTKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDE 179
Cdd:PRK13634 96 HqlFEETVEKDICFGPMNF-GVSEEDAKQKAREMIELVGL---PEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDE 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 180 PCSALDPisTGRIE--ELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAK 245
Cdd:PRK13634 172 PTAGLDP--KGRKEmmEMFYKLhkEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREIFADPDE 239
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-215 |
3.98e-38 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 134.22 E-value: 3.98e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 1 MSMvdtapgkIQVRDLNFYYGKF----HALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKM--FeLYPEqraEGEILL 74
Cdd:COG4525 1 MSM-------LTVRHVSVRYPGGgqpqPALQDVSLTIESGEFVVALGASGCGKTTLL---NLIagF-LAPS---SGEITL 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 75 DGDNILTNTQDiallRakvGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALwnetKDKLHQSGYS 153
Cdd:COG4525 67 DGVPVTGPGAD----R---GVVFQKDALLPwLNVLDNVAFGLRL-RGVPKAERRARAEELLALVGL----ADFARRRIWQ 134
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 154 LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQA 215
Cdd:COG4525 135 LSGGMRQRVGIARALAADPRFLLMDEPFGALDALTREQMQELLLDVwqRTGKGVFLITHSVEEA 198
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
11-220 |
5.65e-38 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 134.09 E-value: 5.65e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK-FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfeLYPEQRaeGEILLDGDNIltNTQDIALL 89
Cdd:PRK13647 5 IEVEDLHFRYKDgTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNG---IYLPQR--GRVKVMGREV--NAENEKWV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTP--FPMSIYDNIAFGVRLFEkLSRADMDERVQWALTKAALWnetkDKLHQSGYSLSGGQQQRLCIARG 167
Cdd:PRK13647 78 RSKVGLVFQDPDDqvFSSTVWDDVAFGPVNMG-LDKDEVERRVEEALKAVRMW----DFRDKPPYHLSYGQKKRVAIAGV 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSD 220
Cdd:PRK13647 153 LAMDPDVIVLDEPMAYLDPRGQETLMEILDRLhNQGKTVIVATHDVDLAAEWAD 206
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
5-243 |
9.25e-38 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 138.66 E-value: 9.25e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 5 DTAPGKIQVRDLNFYY-----------GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypeQRAEGEIL 73
Cdd:COG4172 270 PDAPPLLEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRL------IPSEGEIR 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 74 LDGDNILT-NTQDIALLRAKVGMVFQKPtpF----P-MSIYDNIAFGVRLFE-KLSRADMDERVQWALTKAALWNETKDK 146
Cdd:COG4172 344 FDGQDLDGlSRRALRPLRRRMQVVFQDP--FgslsPrMTVGQIIAEGLRVHGpGLSAAERRARVAEALEEVGLDPAARHR 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 147 L-HQsgysLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTA 223
Cdd:COG4172 422 YpHE----FSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQREHglAYLFISHDLAVVRALAHRVM 497
|
250 260
....*....|....*....|
gi 1897751821 224 FMYLGELIEFSNTDDLFTKP 243
Cdd:COG4172 498 VMKDGKVVEQGPTEQVFDAP 517
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
11-239 |
1.57e-37 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 131.34 E-value: 1.57e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQraeGEILLDGDNILTNTQDIallR 90
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTL--LKPTS---GRATVAGHDVVREPREV---R 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALWnETKDKLHQSgysLSGGQQQRLCIARGIA 169
Cdd:cd03265 73 RRIGIVFQDLSVDDeLTGWENLYIHARLY-GVPGAERRERIDELLDFVGLL-EAADRLVKT---YSGGMRRRLEIARSLV 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:cd03265 148 HRPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFgmTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
20-244 |
3.45e-37 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 134.08 E-value: 3.45e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 20 YGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILTNT---QDIAllrakvgMV 96
Cdd:PRK11432 16 FGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGL-----EKPTEGQIFIDGEDVTHRSiqqRDIC-------MV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 97 FQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALwnetkdklhqSGYS------LSGGQQQRLCIARGIA 169
Cdd:PRK11432 84 FQSYALFPhMSLGENVGYGLKM-LGVPKEERKQRVKEALELVDL----------AGFEdryvdqISGGQQQRVALARALI 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKE--DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:PRK11432 153 LKPKVLLFDEPLSNLDANLRRSMREKIRELQQqfNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPA 229
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
19-215 |
4.19e-37 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 129.47 E-value: 4.19e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQraeGEILLDGDNILTNTQDIALLRAKVGMVFQ 98
Cdd:TIGR01166 1 YPGGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGL--LRPQS---GAVLIDGEPLDYSRKGLLERRQRVGLVFQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 99 KPTP--FPMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIAIRPEVLL 176
Cdd:TIGR01166 76 DPDDqlFAADVDQDVAFGPLNL-GLSEAEVERRVREALTAVGASGLRERPTHC----LSGGEKKRVAIAGAVAMRPDVLL 150
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1897751821 177 LDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQA 215
Cdd:TIGR01166 151 LDEPTAGLDPAGREQMLAILRRLRAEgMTVVISTHDVDLA 190
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
11-210 |
4.45e-37 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 130.43 E-value: 4.45e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK--FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNIltntQDIAL 88
Cdd:cd03251 1 VEFKNVTFRYPGdgPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDV-----DSGRILIDGHDV----RDYTL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 --LRAKVGMVFQKPTPFPMSIYDNIAFGVRlfeklsRADMDERVQWAltKAALWNETKDKLHQS--------GYSLSGGQ 158
Cdd:cd03251 72 asLRRQIGLVSQDVFLFNDTVAENIAYGRP------GATREEVEEAA--RAANAHEFIMELPEGydtvigerGVKLSGGQ 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTH 210
Cdd:cd03251 144 RQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIAH 195
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
11-244 |
6.36e-37 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 133.29 E-value: 6.36e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGdniltntQDIALLR 90
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGL-----EHQTSGHIRFHG-------TDVSRLH 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AK---VGMVFQKPTPFP-MSIYDNIAFGVRLF---EKLSRADMDERVQWALTKAALwnetkDKLHQSGYS-LSGGQQQRL 162
Cdd:PRK10851 71 ARdrkVGFVFQHYALFRhMTVFDNIAFGLTVLprrERPNAAAIKAKVTQLLEMVQL-----AHLADRYPAqLSGGQKQRV 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 163 CIARGIAIRPEVLLLDEPCSALDpiSTGRIE------ELITELKedYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNT 236
Cdd:PRK10851 146 ALARALAVEPQILLLDEPFGALD--AQVRKElrrwlrQLHEELK--FTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTP 221
|
....*...
gi 1897751821 237 DDLFTKPA 244
Cdd:PRK10851 222 DQVWREPA 229
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
9-212 |
1.68e-36 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 128.48 E-value: 1.68e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQraEGEILLDGDNIltnTQ-D 85
Cdd:cd03245 1 GRIEFRNVSFSYpnQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKL---LAGLYKPT--SGSVLLDGTDI---RQlD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLfeklsrADmDERVQWALTKAALWNETKD-------KLHQSGYSLSGGQ 158
Cdd:cd03245 73 PADLRRNIGYVPQDVTLFYGTLRDNITLGAPL------AD-DERILRAAELAGVTDFVNKhpngldlQIGERGRGLSGGQ 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNM 212
Cdd:cd03245 146 RQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGDKTLIIITHRP 199
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
9-213 |
1.84e-36 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 136.53 E-value: 1.84e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNF-YYG-KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQraEGEILLDGDNIltnTQ-D 85
Cdd:TIGR03375 462 GEIEFRNVSFaYPGqETPALDNVSLTIRPGEKVAIIGRIGSGKSTLLKL---LLGLYQPT--EGSVLLDGVDI---RQiD 533
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEklsradmDERVQWALTKAALWNETKD-------KLHQSGYSLSGGQ 158
Cdd:TIGR03375 534 PADLRRNIGYVPQDPRLFYGTLRDNIALGAPYAD-------DEEILRAAELAGVTEFVRRhpdgldmQIGERGRSLSGGQ 606
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQ 213
Cdd:TIGR03375 607 RQAVALARALLRDPPILLLDEPTSAMDNRSEERFKDRLKRWLAGKTLVLVTHRTS 661
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
25-244 |
2.15e-36 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 132.53 E-value: 2.15e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPeqrAEGEILLDGDNILTNTQD--IALLRAKVGMVFQKPTP 102
Cdd:COG4175 42 GVNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIE--P---TAGEVLIDGEDITKLSKKelRELRRKKMSMVFQHFAL 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 103 FP-MSIYDNIAFG--VRlfeKLSRADMDERVQWALTKAAL--WnetKDKL-HQsgysLSGGQQQRLCIARGIAIRPEVLL 176
Cdd:COG4175 117 LPhRTVLENVAFGleIQ---GVPKAERRERAREALELVGLagW---EDSYpDE----LSGGMQQRVGLARALATDPDILL 186
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 177 LDEPCSALDPIstgrI-----EELIT---ELKEdyTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:COG4175 187 MDEAFSALDPL----IrremqDELLElqaKLKK--TIVFITHDLDEALRLGDRIAIMKDGRIVQIGTPEEILTNPA 256
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
11-244 |
1.23e-35 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 132.89 E-value: 1.23e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK----FHALKNINLDIAKNQVTAFIGPSGCGKS----TLLRtfnkmfeLYPEQ--RAEGEILLDGDNIL 80
Cdd:COG4172 7 LSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILR-------LLPDPaaHPSGSILFDGQDLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 81 TntQDIALLRA----KVGMVFQKP----TPFpMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwNETKDKL----H 148
Cdd:COG4172 80 G--LSERELRRirgnRIAMIFQEPmtslNPL-HTIGKQIAEVLRLHRGLSGAAARARALELLERVGI-PDPERRLdaypH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 149 QsgysLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMY 226
Cdd:COG4172 156 Q----LSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELgmALLLITHDLGVVRRFADRVAVMR 231
|
250
....*....|....*...
gi 1897751821 227 LGELIEFSNTDDLFTKPA 244
Cdd:COG4172 232 QGEIVEQGPTAELFAAPQ 249
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
26-231 |
1.37e-35 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 126.26 E-value: 1.37e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKN---QVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGDNILTNTQDIAL--LRAKVGMVFQKP 100
Cdd:cd03297 10 LPDFTLKIDFDlneEVTGIFGASGAGKSTLLRCIAGLEKPD-----GGTIVLNGTVLFDSRKKINLppQQRKIGLVFQQY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 101 TPFP-MSIYDNIAFGVRlfeKLSRADMDERVQWALTKAALwnetkDKLHQSG-YSLSGGQQQRLCIARGIAIRPEVLLLD 178
Cdd:cd03297 85 ALFPhLNVRENLAFGLK---RKRNREDRISVDELLDLLGL-----DHLLNRYpAQLSGGEKQRVALARALAAQPELLLLD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 179 EPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:cd03297 157 EPFSALDRALRLQLLPELKQIKKNLniPVIFVTHDLSEAEYLADRIVVMEDGRLQ 211
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
19-239 |
5.82e-35 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 126.74 E-value: 5.82e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGDNIltnTQDIALLRAKVGMVFQ 98
Cdd:TIGR01188 2 VYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTL--LRPT---SGTARVAGYDV---VREPRKVRRSIGIVPQ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 99 KPTPFP-MSIYDNIAFGVRLFEkLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIAIRPEVLLL 177
Cdd:TIGR01188 74 YASVDEdLTGRENLEMMGRLYG-LPKDEAEERAEELLELFELGEAADRPVGT----YSGGMRRRLDIAASLIHQPDVLFL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 178 DEPCSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:TIGR01188 149 DEPTTGLDPRTRRAIWDYIRALKEeGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEEL 211
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
20-218 |
2.89e-34 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 122.34 E-value: 2.89e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 20 YGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNI--LTNTQDIALLRAKVGMVF 97
Cdd:TIGR03608 8 FGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLL-----EKFDSGQVYLNGQETppLNSKKASKFRREKLGYLF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 98 QKptpFPM----SIYDNIAFGVrLFEKLSRADMDERVQWALTKAALWNetkdKLHQSGYSLSGGQQQRLCIARGIAIRPE 173
Cdd:TIGR03608 83 QN---FALieneTVEENLDLGL-KYKKLSKKEKREKKKEALEKVGLNL----KLKQKIYELSGGEQQRVALARAILKPPP 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1897751821 174 VLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARC 218
Cdd:TIGR03608 155 LILADEPTGSLDPKNRDEVLDLLLELnDEGKTIIIVTHDPEVAKQA 200
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
4-210 |
3.91e-34 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 128.98 E-value: 3.91e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 4 VDTAPGKIQVRDLNFYY-GKFH-ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGDNIlt 81
Cdd:PRK11176 335 IERAKGDIEFRNVTFTYpGKEVpALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDID-----EGEILLDGHDL-- 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 82 ntQDIAL--LRAKVGMVFQKPTPFPMSIYDNIAFGVRlfEKLSRADMDERvqwalTKAALWNETKDKLHQ--------SG 151
Cdd:PRK11176 408 --RDYTLasLRNQVALVSQNVHLFNDTIANNIAYART--EQYSREQIEEA-----ARMAYAMDFINKMDNgldtvigeNG 478
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 152 YSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTH 210
Cdd:PRK11176 479 VLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAH 537
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
10-241 |
4.31e-34 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 123.59 E-value: 4.31e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 10 KIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQraeGEILLDGDNILTNT-----Q 84
Cdd:PRK11231 2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARL--LTPQS---GTVFLGDKPISMLSsrqlaR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIALLRAkvgmvfQKPTPFPMSIYDNIAFG----VRLFEKLSRADmDERVQWALTKAALwNETKDKLHQsgySLSGGQQQ 160
Cdd:PRK11231 77 RLALLPQ------HHLTPEGITVRELVAYGrspwLSLWGRLSAED-NARVNQAMEQTRI-NHLADRRLT---DLSGGQRQ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 161 RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:PRK11231 146 RAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNtQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEV 225
|
..
gi 1897751821 240 FT 241
Cdd:PRK11231 226 MT 227
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
11-242 |
4.40e-34 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 122.98 E-value: 4.40e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYG--KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFelYPEQraeGEILLDGDNIltNTQDIAL 88
Cdd:cd03252 1 ITFEHVRFRYKpdGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFY--VPEN---GRVLVDGHDL--ALADPAW 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKVGMVFQKPTPFPMSIYDNIAfgvrlfekLSRADMD-ERVQWAlTKAALWNETKDKLH--------QSGYSLSGGQQ 159
Cdd:cd03252 74 LRRQVGVVLQENVLFNRSIRDNIA--------LADPGMSmERVIEA-AKLAGAHDFISELPegydtivgEQGAGLSGGQR 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMqQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:cd03252 145 QRIAIARALIHNPRILIFDEATSALDYESEHAIMRNMHDICAGRTVIIIAHRL-STVKNADRIIVMEKGRIVEQGSHDEL 223
|
...
gi 1897751821 240 FTK 242
Cdd:cd03252 224 LAE 226
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
12-225 |
5.03e-34 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 121.60 E-value: 5.03e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNF-YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILTNTqdialLR 90
Cdd:cd03226 1 RIENISFsYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGL-----IKESSGSILLNGKPIKAKE-----RR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTP--FPMSIYDNIAFGVRLFeklsrADMDERVQWALTKAALWnETKDKLHQSgysLSGGQQQRLCIARGI 168
Cdd:cd03226 71 KSIGYVMQDVDYqlFTDSVREELLLGLKEL-----DAGNEQAETVLKDLDLY-ALKERHPLS---LSGGQKQRLAIAAAL 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFM 225
Cdd:cd03226 142 LSGKDLLIFDEPTSGLDYKNMERVGELIRELaAQGKAVIVITHDYEFLAKVCDRVLLL 199
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
11-211 |
5.21e-34 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 122.13 E-value: 5.21e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY-GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNI--LTNTQdIA 87
Cdd:cd03292 1 IEFINVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKE-----ELPTSGTIRVNGQDVsdLRGRA-IP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKlSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIAR 166
Cdd:cd03292 75 YLRRKIGVVFQDFRLLPdRNVYENVAFALEVTGV-PPREIRKRVPAALELVGL----SHKHRALPAELSGGEQQRVAIAR 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHN 211
Cdd:cd03292 150 AIVNSPTILIADEPTGNLDPDTTWEIMNLLKKInKAGTTVVVATHA 195
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
11-247 |
6.21e-34 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 122.38 E-value: 6.21e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTllrTFNKMFELYPeqRAEGEILLDGdniltntQDIALL- 89
Cdd:TIGR04406 2 LVAENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTT---SFYMIVGLVR--PDAGKILIDG-------QDITHLp 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 ---RAKVGMVF--QKPTPF-PMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLC 163
Cdd:TIGR04406 70 mheRARLGIGYlpQEASIFrKLTVEENIMAVLEIRKDLDRAEREERLEALLEEFQI----SHLRDNKAMSLSGGERRRVE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:TIGR04406 146 IARALATNPKFILLDEPFAGVDPIAVGDIKKIIKHLKErGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEIVAN 225
|
....*
gi 1897751821 243 PAKKQ 247
Cdd:TIGR04406 226 EKVRR 230
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
11-212 |
6.54e-34 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 122.34 E-value: 6.54e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNF-YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQraEGEILLDGDNILTNTQDIalL 89
Cdd:cd03253 1 IEFENVTFaYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRL---LFRFYDVS--SGSILIDGQDIREVTLDS--L 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFPMSIYDNIAFG------VRLFEKLSRADMDERVQwaltkaALWNETKDKLHQSGYSLSGGQQQRLC 163
Cdd:cd03253 74 RRAIGVVPQDTVLFNDTIGYNIRYGrpdatdEEVIEAAKAAQIHDKIM------RFPDGYDTIVGERGLKLSGGEKQRVA 147
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNM 212
Cdd:cd03253 148 IARAILKNPPILLLDEATSALDTHTEREIQAALRDVSKGRTTIVIAHRL 196
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
3-230 |
6.95e-34 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 122.19 E-value: 6.95e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 3 MVDTAPGKIQVRDLNFYYGK---FHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMFELYPEQraEGEILLDGDNI 79
Cdd:cd03248 4 APDHLKGIVKFQNVTFAYPTrpdTLVLQDVSFTLHPGEVTALVGPSGSGKSTVV---ALLENFYQPQ--GGQVLLDGKPI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 80 ltNTQDIALLRAKVGMVFQKPTPFPMSIYDNIAFGvrlfekLSRADMDERVQWALTKAA----------LWNETKDKlhq 149
Cdd:cd03248 79 --SQYEHKYLHSKVSLVGQEPVLFARSLQDNIAYG------LQSCSFECVKEAAQKAHAhsfiselasgYDTEVGEK--- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 150 sGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARcSDHTAFMYLGE 229
Cdd:cd03248 148 -GSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVER-ADQILVLDGGR 225
|
.
gi 1897751821 230 L 230
Cdd:cd03248 226 I 226
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
26-243 |
8.63e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 123.40 E-value: 8.63e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNILTNTQDIAL--LRAKVGMVFQKPTP- 102
Cdd:PRK13641 23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNAL--LKP---SSGTITIAGYHITPETGNKNLkkLRKKVSLVFQFPEAq 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 103 -FPMSIYDNIAFGVRLFEKLSRADMDERVQWaLTKAALWNETKDKlhqSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPC 181
Cdd:PRK13641 98 lFENTVLKDVEFGPKNFGFSEDEAKEKALKW-LKKVGLSEDLISK---SPFELSGGQMRRVAIAGVMAYEPEILCLDEPA 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 182 SALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKP 243
Cdd:PRK13641 174 AGLDPEGRKEMMQLFKDYqKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDK 236
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
26-232 |
1.07e-33 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 121.80 E-value: 1.07e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILTNTQDIALlrakvgmVFQKPTPFP- 104
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGL-----AQPTSGGVILEGKQITEPGPDRMV-------VFQNYSLLPw 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 105 MSIYDNIAFGV-RLFEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIAIRPEVLLLDEPCSA 183
Cdd:TIGR01184 69 LTVRENIALAVdRVLPDLSKSERRAIVEEHIALVGLTEAADKRPGQ----LSGGMKQRVAIARALSIRPKVLLLDEPFGA 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 184 LDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFM------YLGELIE 232
Cdd:TIGR01184 145 LDALTRGNLQEELMQIWEEHrvTVLMVTHDVDEALLLSDRVVMLtngpaaNIGQILE 201
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
10-251 |
1.11e-33 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 123.35 E-value: 1.11e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 10 KIQVRDLNFYYGK-----FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNILTNTQ 84
Cdd:PRK13646 2 TIRFDNVSYTYQKgtpyeHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINAL--LKP---TTGTVTVDDITITHKTK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 D--IALLRAKVGMVFQKPTP--FPMSIYDNIAFGVRLFeklsRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ 160
Cdd:PRK13646 77 DkyIRPVRKRIGMVFQFPESqlFEDTVEREIIFGPKNF----KMNLDEVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 161 RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDD 238
Cdd:PRK13646 153 KIAIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLqtDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKE 232
|
250
....*....|...
gi 1897751821 239 LFTKpaKKQTEDY 251
Cdd:PRK13646 233 LFKD--KKKLADW 243
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
11-215 |
1.34e-33 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 124.76 E-value: 1.34e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIltntQDIALLR 90
Cdd:PRK11000 4 VTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGL-----EDITSGDLFIGEKRM----NDVPPAE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWA---LTKAALWnETKDKlhqsgySLSGGQQQRLCIAR 166
Cdd:PRK11000 75 RGVGMVFQSYALYPhLSVAENMSFGLKL-AGAKKEEINQRVNQVaevLQLAHLL-DRKPK------ALSGGQRQRVAIGR 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPI--STGRIEelITEL--KEDYTVVIVTHNMQQA 215
Cdd:PRK11000 147 TLVAEPSVFLLDEPLSNLDAAlrVQMRIE--ISRLhkRLGRTMIYVTHDQVEA 197
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
12-216 |
1.48e-33 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 120.66 E-value: 1.48e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMF-ELYPEQRAEGEILLDGdniltntQDIALLR 90
Cdd:COG4136 3 SLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLL---AAIAgTLSPAFSASGEVLLNG-------RRLTALP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 A---KVGMVFQKPTPFP-MSIYDNIAFGVRlfEKLSRADMDERVQWALTKAALwnetkdklhqSGY------SLSGGQQQ 160
Cdd:COG4136 73 AeqrRIGILFQDDLLFPhLSVGENLAFALP--PTIGRAQRRARVEQALEEAGL----------AGFadrdpaTLSGGQRA 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 161 RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELI-TELKE-DYTVVIVTHNMQQAA 216
Cdd:COG4136 141 RVALLRALLAEPRALLLDEPFSKLDAALRAQFREFVfEQIRQrGIPALLVTHDEEDAP 198
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
12-239 |
2.10e-33 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 120.71 E-value: 2.10e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQRaeGEILLDGDNIltnTQDIALLRA 91
Cdd:TIGR03410 2 EVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKT---LMGLLPVKS--GSIRLDGEDI---TKLPPHERA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 92 KVGM--VFQKPTPFP-MSIYDNIAFGvrlFEKLSRAD--MDERVqwaltkAALWNETKDKLHQSGYSLSGGQQQRLCIAR 166
Cdd:TIGR03410 74 RAGIayVPQGREIFPrLTVEENLLTG---LAALPRRSrkIPDEI------YELFPVLKEMLGRRGGDLSGGQQQQLAIAR 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPISTGRIEELITELKE--DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:TIGR03410 145 ALVTRPKLLLLDEPTEGIQPSIIKDIGRVIRRLRAegGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDEL 219
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
11-221 |
3.37e-33 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 121.41 E-value: 3.37e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPEQraeGEILLDGDNILTNT-QDIALL 89
Cdd:PRK11831 8 VDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGG--QIAPDH---GEILFDGENIPAMSrSRLYTV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETkdKLHQSgySLSGGQQQRLCIARGI 168
Cdd:PRK11831 83 RKRMSMLFQSGALFTdMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAA--KLMPS--ELSGGMARRAALARAI 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKE--DYTVVIVTHNMQQAARCSDH 221
Cdd:PRK11831 159 ALEPDLIMFDEPFVGQDPITMGVLVKLISELNSalGVTCVVVSHDVPEVLSIADH 213
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
11-210 |
5.20e-33 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 119.22 E-value: 5.20e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAkNQVTAFIGPSGCGKSTLLRTFNKMFElyPEqraEGEILLDGDNILTNTQDIallR 90
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLG-PGMYGLLGPNGAGKTTLMRILATLTP--PS---SGTIRIDGQDVLKQPQKL---R 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNETKDKLHqsgySLSGGQQQRLCIARGIA 169
Cdd:cd03264 72 RRIGYLPQEFGVYPnFTVREFLDYIAWL-KGIPSKEVKARVDEVLELVNLGDRAKKKIG----SLSGGMRRRVGIAQALV 146
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTH 210
Cdd:cd03264 147 GDPSILIVDEPTAGLDPEERIRFRNLLSELGEDRIVILSTH 187
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
11-222 |
6.31e-33 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 125.48 E-value: 6.31e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY-GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGDNILTNTQDiaLL 89
Cdd:TIGR02857 322 LEFSGVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPT-----EGSIAVNGVPLADADAD--SW 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFPMSIYDNIAFGvrlfeklsRADM-DERVQWALTKAALWNETKD-------KLHQSGYSLSGGQQQR 161
Cdd:TIGR02857 395 RDQIAWVPQHPFLFAGTIAENIRLA--------RPDAsDAEIREALERAGLDEFVAAlpqgldtPIGEGGAGLSGGQAQR 466
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 162 LCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHT 222
Cdd:TIGR02857 467 LALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQGRTVLLVTHRLALAALA-DRI 526
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
11-232 |
1.74e-32 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 117.70 E-value: 1.74e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQraEGEILLDGDNILTNTQDiallR 90
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKI---ILGLIKPD--SGEITFDGKSYQKNIEA----L 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLsradmDERVQWALTKAALWNETKDKLhqSGYSLsgGQQQRLCIARGIA 169
Cdd:cd03268 72 RRIGALIEAPGFYPnLTARENLRLLARLLGIR-----KKRIDEVLDVVGLKDSAKKKV--KGFSL--GMKQRLGIALALL 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIE 232
Cdd:cd03268 143 GNPDLLILDEPTNGLDPDGIKELRELILSLrDQGITVLISSHLLSEIQKVADRIGIINKGKLIE 206
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
11-243 |
2.29e-32 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 119.52 E-value: 2.29e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY-GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNIltNTQDIALL 89
Cdd:PRK13652 4 IETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGI--LKP---TSGSVLIRGEPI--TKENIREV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTP--FPMSIYDNIAFG-VRLfeKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIAR 166
Cdd:PRK13652 77 RKFVGLVFQNPDDqiFSPTVEQDIAFGpINL--GLDEETVAHRVSSALHMLGL----EELRDRVPHHLSGGEKKRVAIAG 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKP 243
Cdd:PRK13652 151 VIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYgmTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
11-231 |
2.84e-32 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 119.83 E-value: 2.84e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGDNIltnTQDIallR 90
Cdd:COG4152 2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGI--LAPD---SGEVLWDGEPL---DPED---R 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVG-M-----VFQKptpfpMSIYDNIAFGVRLfeK-LSRADMDERVQWALTK---AALWNetkDKLHqsgySLSGGQQQ 160
Cdd:COG4152 71 RRIGyLpeergLYPK-----MKVGEQLVYLARL--KgLSKAEAKRRADEWLERlglGDRAN---KKVE----ELSKGNQQ 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 161 RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIV-THNMQQAARCSDHTAFMYLGELI 231
Cdd:COG4152 137 KVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFsSHQMELVEELCDRIVIINKGRKV 208
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
11-241 |
2.87e-32 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 118.94 E-value: 2.87e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFH--ALKNINLDIAKNQVTAFIGPSGCGKSTllrtFNKMFE-LYPEQraEGEILLDGdnILTNTQDIA 87
Cdd:PRK13632 8 IKVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKST----ISKILTgLLKPQ--SGEIKIDG--ITISKENLK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKP-TPF-PMSIYDNIAFGVRlFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIA 165
Cdd:PRK13632 80 EIRKKIGIIFQNPdNQFiGATVEDDIAFGLE-NKKVPPKKMKDIIDDLAKKVGM----EDYLDKEPQNLSGGQKQRVAIA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 166 RGIAIRPEVLLLDEPCSALDPISTGRIEELITELKE--DYTVVIVTHNMQQAARCsDHTAFMYLGELIEFSNTDDLFT 241
Cdd:PRK13632 155 SVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKtrKKTLISITHDMDEAILA-DKVIVFSEGKLIAQGKPKEILN 231
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
25-254 |
3.78e-32 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 121.68 E-value: 3.78e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqRAEGEILLDGDNI--LTNTQDIALLRAKVGMVFQKPTP 102
Cdd:PRK10070 43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIE-----PTRGQVLIDGVDIakISDAELREVRRKKIAMVFQSFAL 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 103 FP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNetkdklHQSGY--SLSGGQQQRLCIARGIAIRPEVLLLDE 179
Cdd:PRK10070 118 MPhMTVLDNTAFGMEL-AGINAEERREKALDALRQVGLEN------YAHSYpdELSGGMRQRVGLARALAINPDILLMDE 190
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 180 PCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITG 254
Cdd:PRK10070 191 AFSALDPLIRTEMQDELVKLqaKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRG 267
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
11-240 |
4.18e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 119.04 E-value: 4.18e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK---FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGDNIltNTQDIA 87
Cdd:PRK13642 5 LEVENLVFKYEKesdVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEF-----EGKVKIDGELL--TAENVW 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKPTP--FPMSIYDNIAFGVRlFEKLSRADMDERVQWALTKAALWN-ETKDKLHqsgysLSGGQQQRLCI 164
Cdd:PRK13642 78 NLRRKIGMVFQNPDNqfVGATVEDDVAFGME-NQGIPREEMIKRVDEALLAVNMLDfKTREPAR-----LSGGQKQRVAV 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 165 ARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARcSDHTAFMYLGELIEFSNTDDLF 240
Cdd:PRK13642 152 AGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYqlTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF 228
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
5-232 |
8.53e-32 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 122.52 E-value: 8.53e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 5 DTAPGKIQVRDLNFYYG--KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEqraEGEILLDGDNIltn 82
Cdd:TIGR02203 325 ERARGDVEFRNVTFRYPgrDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYE--PD---SGQILLDGHDL--- 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 83 tQDIAL--LRAKVGMVFQKPTPFPMSIYDNIAFGVRlfEKLSRADMDERVQWALTKAaLWNETKDKLH----QSGYSLSG 156
Cdd:TIGR02203 397 -ADYTLasLRRQVALVSQDVVLFNDTIANNIAYGRT--EQADRAEIERALAAAYAQD-FVDKLPLGLDtpigENGVLLSG 472
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 157 GQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARcSDHTAFMYLGELIE 232
Cdd:TIGR02203 473 GQRQRLAIARALLKDAPILILDEATSALDNESERLVQAALERLMQGRTTLVIAHRLSTIEK-ADRIVVMDDGRIVE 547
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
25-240 |
9.04e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 117.92 E-value: 9.04e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDgDNILTNT---QDIALLRAKVGMVFQKPT 101
Cdd:PRK13649 22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGL--HVP---TQGSVRVD-DTLITSTsknKDIKQIRKKVGLVFQFPE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 102 P--FPMSIYDNIAFGVRLFEklsrADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDE 179
Cdd:PRK13649 96 SqlFEETVLKDVAFGPQNFG----VSQEEAEALAREKLALVGISESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDE 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 180 PCSALDPisTGRiEELITELKEDY----TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLF 240
Cdd:PRK13649 172 PTAGLDP--KGR-KELMTLFKKLHqsgmTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIF 233
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
11-242 |
1.99e-31 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 116.77 E-value: 1.99e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDgdNILTNTQDIAL 88
Cdd:PRK13648 8 IVFKNVSFQYqsDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGI-----EKVKSGEIFYN--NQAITDDNFEK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKVGMVFQKP-TPFPMSI--YDnIAFGVRLFeKLSRADMDERVQWALTKAALWNETKDKLHqsgySLSGGQQQRLCIA 165
Cdd:PRK13648 81 LRKHIGIVFQNPdNQFVGSIvkYD-VAFGLENH-AVPYDEMHRRVSEALKQVDMLERADYEPN----ALSGGQKQRVAIA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 166 RGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVI--VTHNMQQAARcSDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:PRK13648 155 GVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIisITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDH 232
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
11-231 |
2.69e-31 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 113.29 E-value: 2.69e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYpeQRAEGEILLDGDNILTNTQDIALlR 90
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKI---LSGLY--KPDSGEILVDGKEVSFASPRDAR-R 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQkptpfpmsiydniafgvrlfeklsradmdervqwaltkaalwnetkdklhqsgysLSGGQQQRLCIARGIAI 170
Cdd:cd03216 75 AGIAMVYQ-------------------------------------------------------LSVGERQMVEIARALAR 99
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 171 RPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:cd03216 100 NARLLILDEPTAALTPAEVERLFKVIRRLRAQgVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
11-248 |
3.43e-31 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 115.33 E-value: 3.43e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTllrTFNKMFELypEQRAEGEILLDGdniltntQDIALL- 89
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTT---TFYMIVGL--VKPDSGKILLDG-------QDITKLp 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 ---RAKVGMVF--QKPTPF-PMSIYDNIAfGVRLFEKLSRADMDERVQwaltkaALWNETK-DKL-HQSGYSLSGGQQQR 161
Cdd:cd03218 69 mhkRARLGIGYlpQEASIFrKLTVEENIL-AVLEIRGLSKKEREEKLE------ELLEEFHiTHLrKSKASSLSGGERRR 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 162 LCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLF 240
Cdd:cd03218 142 VEIARALATNPKFLLLDEPFAGVDPIAVQDIQKIIKILKDrGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIA 221
|
....*...
gi 1897751821 241 TKPAKKQT 248
Cdd:cd03218 222 ANELVRKV 229
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
8-211 |
3.60e-31 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 115.13 E-value: 3.60e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 8 PGKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTllrTFNKMFELypEQRAEGEILLDGdniltntQDIA 87
Cdd:COG1137 1 MMTLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTT---TFYMIVGL--VKPDSGRIFLDG-------EDIT 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LL----RAKVGM--------VFQKptpfpMSIYDNIAfGVRLFEKLSRADMDERVQwaltkaALWNETK-DKL-HQSGYS 153
Cdd:COG1137 69 HLpmhkRARLGIgylpqeasIFRK-----LTVEDNIL-AVLELRKLSKKEREERLE------ELLEEFGiTHLrKSKAYS 136
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 154 LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKE-DYTVVIVTHN 211
Cdd:COG1137 137 LSGGERRRVEIARALATNPKFILLDEPFAGVDPIAVADIQKIIRHLKErGIGVLITDHN 195
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
3-232 |
3.71e-31 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 115.22 E-value: 3.71e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 3 MVDTAPGKIQVRDLNFYY----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELypEQRAEGEILLDGDN 78
Cdd:COG4181 1 MSSSSAPIIELRGLTKTVgtgaGELTILKGISLEVEAGESVAIVGASGSGKSTLLGL---LAGL--DRPTSGTVRLAGQD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 79 ILTNTQD-IALLRA-KVGMVFQK----PTpfpMSIYDNIAfgVRLfEKLSRADMDERVQWALTKAALwnetKDKLHQSGY 152
Cdd:COG4181 76 LFALDEDaRARLRArHVGFVFQSfqllPT---LTALENVM--LPL-ELAGRRDARARARALLERVGL----GHRLDHYPA 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 153 SLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPiSTG-RIEELITELKEDY--TVVIVTHNMQQAARCsDHTAFMYLGE 229
Cdd:COG4181 146 QLSGGEQQRVALARAFATEPAILFADEPTGNLDA-ATGeQIIDLLFELNRERgtTLVLVTHDPALAARC-DRVLRLRAGR 223
|
...
gi 1897751821 230 LIE 232
Cdd:COG4181 224 LVE 226
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
3-243 |
1.98e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 114.51 E-value: 1.98e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 3 MVDTApgkIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQRAEGEILLDGDNIl 80
Cdd:PRK13640 1 MKDNI---VEFKHVSFTYpdSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGL--LLPDDNPNSKITVDGITL- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 81 tNTQDIALLRAKVGMVFQKP-TPF-PMSIYDNIAFGVRlFEKLSRADMDERVQWALTKAALWNETKDKLHqsgySLSGGQ 158
Cdd:PRK13640 75 -TAKTVWDIREKVGIVFQNPdNQFvGATVGDDVAFGLE-NRAVPRPEMIKIVRDVLADVGMLDYIDSEPA----NLSGGQ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED--YTVVIVTHNMQQAARcSDHTAFMYLGELIEFSNT 236
Cdd:PRK13640 149 KQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKnnLTVISITHDIDEANM-ADQVLVLDDGKLLAQGSP 227
|
....*..
gi 1897751821 237 DDLFTKP 243
Cdd:PRK13640 228 VEIFSKV 234
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
11-218 |
2.22e-30 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 111.15 E-value: 2.22e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHA--LKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQraEGEILLDGDNIltNTQDIAL 88
Cdd:cd03246 1 LEVENVSFRYPGAEPpvLRNVSFSIEPGESLAIIGPSGSGKSTLARL---ILGLLRPT--SGRVRLDGADI--SQWDPNE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKVGMVFQKPTPFPMSIYDNIafgvrlfeklsradmdervqwaltkaalwnetkdklhqsgysLSGGQQQRLCIARGI 168
Cdd:cd03246 74 LGDHVGYLPQDDELFSGSIAENI------------------------------------------LSGGQRQRLGLARAL 111
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARC 218
Cdd:cd03246 112 YGNPRILVLDEPNSHLDVEGERALNQAIAALKAaGATRIVIAHRPETLASA 162
|
|
| NHLM_micro_ABC2 |
TIGR03797 |
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ... |
9-185 |
2.44e-30 |
|
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 118.91 E-value: 2.44e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYYGK--FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkmfeLYPEQRAEGEILLDGDNILTntQDI 86
Cdd:TIGR03797 450 GAIEVDRVTFRYRPdgPLILDDVSLQIEPGEFVAIVGPSGSGKSTLLRLL-----LGFETPESGSVFYDGQDLAG--LDV 522
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLfeklsraDMDErVQWALTKAALWNETKD---KLH----QSGYSLSGGQQ 159
Cdd:TIGR03797 523 QAVRRQLGVVLQNGRLMSGSIFENIAGGAPL-------TLDE-AWEAARMAGLAEDIRAmpmGMHtvisEGGGTLSGGQR 594
|
170 180
....*....|....*....|....*.
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALD 185
Cdd:TIGR03797 595 QRLLIARALVRKPRILLFDEATSALD 620
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
11-210 |
2.50e-30 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 112.19 E-value: 2.50e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPeqRAEGEILLDGDNIltnTQDIALLR 90
Cdd:COG4133 3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRI---LAGLLP--PSAGEVLWNGEPI---RDAREDYR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLF-EKLSRADMDErvqwALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:COG4133 75 RRLAYLGHADGLKPeLTVRENLRFWAALYgLRADREAIDE----ALEAVGL----AGLADLPVRQLSAGQKRRVALARLL 146
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITE-LKEDYTVVIVTH 210
Cdd:COG4133 147 LSPAPLWLLDEPFTALDAAGVALLAELIAAhLARGGAVLLTTH 189
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
11-242 |
2.67e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 114.06 E-value: 2.67e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK---FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqrAE-GEILLDGDnILT--NTQ 84
Cdd:PRK13650 5 IEVKNLTFKYKEdqeKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLE------AEsGQIIIDGD-LLTeeNVW 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIallRAKVGMVFQKP-TPF-PMSIYDNIAFGVRlFEKLSRADMDERVQWALTKAALwNETKDKlhqSGYSLSGGQQQRL 162
Cdd:PRK13650 78 DI---RHKIGMVFQNPdNQFvGATVEDDVAFGLE-NKGIPHEEMKERVNEALELVGM-QDFKER---EPARLSGGQKQRV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 163 CIARGIAIRPEVLLLDEPCSALDPisTGRIE--ELITELKEDY--TVVIVTHNMQQAArCSDHTAFMYLGELIEFSNTDD 238
Cdd:PRK13650 150 AIAGAVAMRPKIIILDEATSMLDP--EGRLEliKTIKGIRDDYqmTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPRE 226
|
....
gi 1897751821 239 LFTK 242
Cdd:PRK13650 227 LFSR 230
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
9-247 |
4.33e-30 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 117.75 E-value: 4.33e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY-GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPeqrAEGEILLDGDNILTNTqdIA 87
Cdd:PRK13657 333 GAVEFDDVSFSYdNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFD--P---QSGRILIDGTDIRTVT--RA 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKPTPFPMSIYDNIAFGvrlfeklsRAD-MDERVQWALTKAALWN--ETKDKLHQS-----GYSLSGGQQ 159
Cdd:PRK13657 406 SLRRNIAVVFQDAGLFNRSIEDNIRVG--------RPDaTDEEMRAAAERAQAHDfiERKPDGYDTvvgerGRQLSGGER 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMqQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:PRK13657 478 QRLAIARALLKDPPILILDEATSALDVETEAKVKAALDELMKGRTTFIIAHRL-STVRNADRILVFDNGRVVESGSFDEL 556
|
250
....*....|....
gi 1897751821 240 ------FTKPAKKQ 247
Cdd:PRK13657 557 varggrFAALLRAQ 570
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
11-231 |
4.75e-30 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 111.69 E-value: 4.75e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK----FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEQraeGEILLDGDNILTNTQDI 86
Cdd:cd03266 2 ITADALTKRFRDvkktVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLE--PDA---GFATVDGFDVVKEPAEA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 allRAKVGMVFQKPTPFP-MSIYDNIAFGVRLFeKLSRADMDERVQWALTKAalwnETKDKLHQSGYSLSGGQQQRLCIA 165
Cdd:cd03266 77 ---RRRLGFVSDSTGLYDrLTARENLEYFAGLY-GLKGDELTARLEELADRL----GMEELLDRRVGGFSTGMRQKVAIA 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 166 RGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:cd03266 149 RALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRALgKCILFSTHIMQEVERLCDRVVVLHRGRVV 215
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
28-244 |
5.33e-30 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 114.81 E-value: 5.33e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 28 NINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELypEQRAEGEILLDGDNILTNTQDIALLRAK--VGMVFQKPTPFP- 104
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLLRA---IAGL--ERPDSGRIRLGGEVLQDSARGIFLPPHRrrIGYVFQEARLFPh 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 105 MSIYDNIAFGV-RLFEKLSRADMDERVQWaLTKAALwnetkdkLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSA 183
Cdd:COG4148 92 LSVRGNLLYGRkRAPRAERRISFDEVVEL-LGIGHL-------LDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAA 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 184 LDpisTGR-------IEELITELkeDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:COG4148 164 LD---LARkaeilpyLERLRDEL--DIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLSRPD 226
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
9-243 |
5.89e-30 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 117.90 E-value: 5.89e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY---GKFHALKNINLDIAKNQVTAFIGPSGCGKST---LLRTFnkmfelYpeQRAEGEILLDGDNIltn 82
Cdd:TIGR00958 477 GLIEFQDVSFSYpnrPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTvaaLLQNL------Y--QPTGGQVLLDGVPL--- 545
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 83 TQ-DIALLRAKVGMVFQKPTPFPMSIYDNIAFGvrlfekLSRADMDERVQWALTKAA------LWNETKDKLHQSGYSLS 155
Cdd:TIGR00958 546 VQyDHHYLHRQVALVGQEPVLFSGSVRENIAYG------LTDTPDEEIMAAAKAANAhdfimeFPNGYDTEVGEKGSQLS 619
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 156 GGQQQRLCIARGIAIRPEVLLLDEPCSALDpistGRIEELITELKE--DYTVVIVTHNMQQAARCsDHTAFMYLGELIEF 233
Cdd:TIGR00958 620 GGQKQRIAIARALVRKPRVLILDEATSALD----AECEQLLQESRSraSRTVLLIAHRLSTVERA-DQILVLKKGSVVEM 694
|
250
....*....|
gi 1897751821 234 SNTDDLFTKP 243
Cdd:TIGR00958 695 GTHKQLMEDQ 704
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
25-242 |
6.73e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 113.29 E-value: 6.73e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFelypeQRAEGEILLdGDNILTNT---QDIALLRAKVGMVFQKPT 101
Cdd:PRK13643 21 ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLL-----QPTEGKVTV-GDIVVSSTskqKEIKPVRKKVGVVFQFPE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 102 P--FPMSIYDNIAFGVRLFeKLSRadmDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDE 179
Cdd:PRK13643 95 SqlFEETVLKDVAFGPQNF-GIPK---EKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDE 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 180 PCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:PRK13643 171 PTAGLDPKARIEMMQLFESIHQSgQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQE 234
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
9-210 |
6.74e-30 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 111.43 E-value: 6.74e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNIltntQDI 86
Cdd:cd03244 1 GDIEFKNVSLRYrpNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVEL-----SSGSILIDGVDI----SKI 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 AL--LRAKVGMVFQKPTPFPMSIYDNIAFgvrlFEKLSradmDERVQWALTKAALWNETK-------DKLHQSGYSLSGG 157
Cdd:cd03244 72 GLhdLRSRISIIPQDPVLFSGTIRSNLDP----FGEYS----DEELWQALERVGLKEFVEslpggldTVVEEGGENLSVG 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 158 QQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELI-TELKeDYTVVIVTH 210
Cdd:cd03244 144 QRQLLCLARALLRKSKILVLDEATASVDPETDALIQKTIrEAFK-DCTVLTIAH 196
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
11-243 |
1.10e-29 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 113.52 E-value: 1.10e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY----GKF------HALKNINLDIAKNQVTAFIGPSGCGKSTLLRtfnkMFELYpEQRAEGEILLDGDNIL 80
Cdd:PRK11308 6 LQAIDLKKHYpvkrGLFkperlvKALDGVSFTLERGKTLAVVGESGCGKSTLAR----LLTMI-ETPTGGELYYQGQDLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 81 TN-TQDIALLRAKVGMVFQKPTPfpmSIYDNIAFGVRLFE------KLSRADMDERVQWALTKAALWNEtkdklHQSGYS 153
Cdd:PRK11308 81 KAdPEAQKLLRQKIQIVFQNPYG---SLNPRKKVGQILEEpllintSLSAAERREKALAMMAKVGLRPE-----HYDRYP 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 154 --LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTV--VIVTHNMQQAARCSDHTAFMYLGE 229
Cdd:PRK11308 153 hmFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLsyVFISHDLSVVEHIADEVMVMYLGR 232
|
250
....*....|....
gi 1897751821 230 LIEFSNTDDLFTKP 243
Cdd:PRK11308 233 CVEKGTKEQIFNNP 246
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
11-225 |
1.11e-29 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 110.25 E-value: 1.11e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK-----FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELypeQRAEGEILLDGdniltntqd 85
Cdd:cd03250 1 ISVEDASFTWDSgeqetSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSAL--LGEL---EKLSGSVSVPG--------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 iallraKVGMVFQKPTPFPMSIYDNIAFGvrlfeklsrADMD-ERVQWALTKAALwneTKD----------KLHQSGYSL 154
Cdd:cd03250 67 ------SIAYVSQEPWIQNGTIRENILFG---------KPFDeERYEKVIKACAL---EPDleilpdgdltEIGEKGINL 128
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 155 SGGQQQRLCIARGIAIRPEVLLLDEPCSALDPiSTGR--IEELIT-ELKEDYTVVIVTHNMQQAARCsDHTAFM 225
Cdd:cd03250 129 SGGQKQRISLARAVYSDADIYLLDDPLSAVDA-HVGRhiFENCILgLLLNNKTRILVTHQLQLLPHA-DQIVVL 200
|
|
| ABC_ATP_DarD |
NF038007 |
darobactin export ABC transporter ATP-binding protein; |
22-230 |
1.81e-29 |
|
darobactin export ABC transporter ATP-binding protein;
Pssm-ID: 411600 [Multi-domain] Cd Length: 218 Bit Score: 110.19 E-value: 1.81e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 22 KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNkMFElypeQRAEGEILLDGDNI--LTNTQDIALLRAKVGMVFQK 99
Cdd:NF038007 17 KTKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIG-MFD----SLDSGSLTLAGKEVtnLSYSQKIILRRELIGYIFQS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 100 PTPFP-MSIYDNIAFGVRlFEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIAIRPEVLLLD 178
Cdd:NF038007 92 FNLIPhLSIFDNVALPLK-YRGVAKKERIERVNQVLNLFGIDNRRNHKPMQ----LSGGQQQRVAIARAMVSNPALLLAD 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 179 EPCSALDPIST-GRIEELITELKEDYTVVIVTHNmQQAARCSDHTAFMYLGEL 230
Cdd:NF038007 167 EPTGNLDSKNArAVLQQLKYINQKGTTIIMVTHS-DEASTYGNRIINMKDGKL 218
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
4-211 |
2.41e-29 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 115.54 E-value: 2.41e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 4 VDTAPGkIQVRDLNFYY-GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQRaeGEILLDGDNILTN 82
Cdd:TIGR02868 329 GLGKPT-LELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLAT---LAGLLDPLQ--GEVTLDGVPVSSL 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 83 TQDiaLLRAKVGMVFQKPTPFPMSIYDNIAFGvrlfeklsRADM-DERVQWALTKAALWN---ETKD----KLHQSGYSL 154
Cdd:TIGR02868 403 DQD--EVRRRVSVCAQDAHLFDTTVRENLRLA--------RPDAtDEELWAALERVGLADwlrALPDgldtVLGEGGARL 472
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 155 SGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHN 211
Cdd:TIGR02868 473 SGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLAALSGRTVVLITHH 529
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
11-232 |
4.99e-29 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 108.17 E-value: 4.99e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYG--KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPEQraeGEILLDGDNILTNTqdiAL 88
Cdd:cd03247 1 LSINNVSFSYPeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTG--DLKPQQ---GEITLDGVPVSDLE---KA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKVGMVFQKPTPFPMSIYDNIafgvrlfeklsradmdervqwaltkaalwnetkdklhqsGYSLSGGQQQRLCIARGI 168
Cdd:cd03247 73 LSSLISVLNQRPYLFDTTLRNNL---------------------------------------GRRFSGGERQRLALARIL 113
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARcSDHTAFMYLGELIE 232
Cdd:cd03247 114 LQDAPIVLLDEPTVGLDPITERQLLSLIFEVLKDKTLIWITHHLTGIEH-MDKILFLENGKIIM 176
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
9-239 |
5.08e-29 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 115.22 E-value: 5.08e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYYG-KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFelypeQRAEGEILLDGDNIltNTQDIA 87
Cdd:TIGR01193 472 GDIVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFF-----QARSGEILLNGFSL--KDIDRH 544
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKPTPFPMSIYDNIAFGVRlfEKLSRADMDERVQWALTKAALWNET---KDKLHQSGYSLSGGQQQRLCI 164
Cdd:TIGR01193 545 TLRQFINYLPQEPYIFSGSILENLLLGAK--ENVSQDEIWAACEIAEIKDDIENMPlgyQTELSEEGSSISGGQKQRIAL 622
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 165 ARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKeDYTVVIVTHNMQQAARcSDHTAFMYLGELIEFSNTDDL 239
Cdd:TIGR01193 623 ARALLTDSKVLILDESTSNLDTITEKKIVNNLLNLQ-DKTIIFVAHRLSVAKQ-SDKIIVLDHGKIIEQGSHDEL 695
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
19-185 |
5.29e-29 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 112.24 E-value: 5.29e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRtfnkMFE-LypEQRAEGEILLDGDNIltNT-----QDIAllrak 92
Cdd:PRK11650 13 YDGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLR----MVAgL--ERITSGEIWIGGRVV--NElepadRDIA----- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 93 vgMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQwaltKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIR 171
Cdd:PRK11650 80 --MVFQNYALYPhMSVRENMAYGLKI-RGMPKAEIEERVA----EAARILELEPLLDRKPRELSGGQRQRVAMGRAIVRE 152
|
170
....*....|....
gi 1897751821 172 PEVLLLDEPCSALD 185
Cdd:PRK11650 153 PAVFLFDEPLSNLD 166
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
26-247 |
6.16e-29 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 110.28 E-value: 6.16e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkmfeLYPEQRAEGEILLDGDNI--LTNTQDIALLRaKVGMVFQK-PTP 102
Cdd:TIGR02769 27 LTNVSLSIEEGETVGLLGRSGCGKSTLARLL-----LGLEKPAQGTVSFRGQDLyqLDRKQRRAFRR-DVQLVFQDsPSA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 103 F--PMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSgysLSGGQQQRLCIARGIAIRPEVLLLDEP 180
Cdd:TIGR02769 101 VnpRMTVRQIIGEPLRHLTSLDESEQKARIAELLDMVGLRSEDADKLPRQ---LSGGQLQRINIARALAVKPKLIVLDEA 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 181 CSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFT--KPAKKQ 247
Cdd:TIGR02769 178 VSNLDMVLQAVILELLRKLQQAFgtAYLFITHDLRLVQSFCQRVAVMDKGQIVEECDVAQLLSfkHPAGRN 248
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
11-231 |
7.33e-29 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 110.18 E-value: 7.33e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY-----GKFH-ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNIlTNTQ 84
Cdd:PRK13633 5 IKCKNVSYKYesneeSTEKlALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNAL--LIP---SEGKVYVDGLDT-SDEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIALLRAKVGMVFQKPtpfpmsiyDN----------IAFGVrlfEKLSRA--DMDERVQWALTKAALWNETKDKLHQsgy 152
Cdd:PRK13633 79 NLWDIRNKAGMVFQNP--------DNqivativeedVAFGP---ENLGIPpeEIRERVDESLKKVGMYEYRRHAPHL--- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 153 sLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPIstGRIEEL--ITELKEDY--TVVIVTHNMQQAARcSDHTAFMYLG 228
Cdd:PRK13633 145 -LSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPS--GRREVVntIKELNKKYgiTIILITHYMEEAVE-ADRIIVMDSG 220
|
...
gi 1897751821 229 ELI 231
Cdd:PRK13633 221 KVV 223
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
22-244 |
8.06e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 111.10 E-value: 8.06e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 22 KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMF----------ELYPEQRAEGEILLDGDNiLTNTQDIALLRA 91
Cdd:PRK13631 38 ELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIkskygtiqvgDIYIGDKKNNHELITNPY-SKKIKNFKELRR 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 92 KVGMVFQKP--TPFPMSIYDNIAFG-VRLfeKLSRADMDERVQWALTKAALwneTKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:PRK13631 117 RVSMVFQFPeyQLFKDTIEKDIMFGpVAL--GVKKSEAKKLAKFYLNKMGL---DDSYLERSPFGLSGGQKRRVAIAGIL 191
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:PRK13631 192 AIQPEILIFDEPTAGLDPKGEHEMMQLILDAKaNNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTDQH 268
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
3-231 |
1.13e-28 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 109.69 E-value: 1.13e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 3 MVDTaPGKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNILT- 81
Cdd:PRK10253 1 MTES-VARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRL--MTP---AHGHVWLDGEHIQHy 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 82 NTQDIAllrAKVGMVFQKP-TPFPMSIYDNIAFGVR----LFEKLSRADMDervqwALTKAALWNETKDKLHQSGYSLSG 156
Cdd:PRK10253 75 ASKEVA---RRIGLLAQNAtTPGDITVQELVARGRYphqpLFTRWRKEDEE-----AVTKAMQATGITHLADQSVDTLSG 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 157 GQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED--YTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:PRK10253 147 GQRQRAWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREkgYTLAAVLHDLNQACRYASHLIALREGKIV 223
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
9-241 |
1.33e-28 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 109.71 E-value: 1.33e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYYGK-----FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDniLTNT 83
Cdd:PRK13645 5 KDIILDNVSYTYAKktpfeFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPAN--LKKI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 84 QDIALLRAKVGMVFQKP--TPFPMSIYDNIAFG-VRLFEklSRADMDERVQWALTKAALwneTKDKLHQSGYSLSGGQQQ 160
Cdd:PRK13645 83 KEVKRLRKEIGLVFQFPeyQLFQETIEKDIAFGpVNLGE--NKQEAYKKVPELLKLVQL---PEDYVKRSPFELSGGQKR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 161 RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYT--VVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDD 238
Cdd:PRK13645 158 RVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKkrIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFE 237
|
...
gi 1897751821 239 LFT 241
Cdd:PRK13645 238 IFS 240
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
11-225 |
2.62e-28 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 107.19 E-value: 2.62e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGkfHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmFELypeqRAEGEILLDGdniltntQDIALL- 89
Cdd:cd03298 1 VRLDKIRFSYG--EQPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAG-FET----PQSGRVLING-------VDVTAAp 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 --RAKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLsRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIAR 166
Cdd:cd03298 67 paDRPVSMLFQENNLFAhLTVEQNVGLGLSPGLKL-TAEDRQAIEVALARVGLAGLEKRLPGE----LSGGERQRVALAR 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPISTGRIEELITELKED--YTVVIVTHNMQQAARCSDHTAFM 225
Cdd:cd03298 142 VLVRDKPVLLLDEPFAALDPALRAEMLDLVLDLHAEtkMTVLMVTHQPEDAKRLAQRVVFL 202
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
11-231 |
2.78e-28 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 108.32 E-value: 2.78e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPEQraeGEILLDGDNIL-TNTQDIALL 89
Cdd:PRK13548 3 LEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSG--ELSPDS---GEVRLNGRPLAdWSPAELARR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAkvgMVFQKPT-PFPMSIYDNIAFGvRLFEKLSRADMDERVQWALTKAALWnETKDKLHQsgySLSGGQQQRLCIARGI 168
Cdd:PRK13548 78 RA---VLPQHSSlSFPFTVEEVVAMG-RAPHGLSRAEDDALVAAALAQVDLA-HLAGRDYP---QLSGGEQQRVQLARVL 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 169 A------IRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:PRK13548 150 AqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLahERGLAVIVVLHDLNLAARYADRIVLLHQGRLV 220
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
24-244 |
4.83e-28 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 109.82 E-value: 4.83e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 24 HALKnINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGDNILTNTQDIALL--RAKVGMVFQKPT 101
Cdd:TIGR02142 12 FSLD-ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPD-----EGEIVLNGRTLFDSRKGIFLPpeKRRIGYVFQEAR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 102 PFP-MSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALwnetkdkLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEP 180
Cdd:TIGR02142 86 LFPhLSVRGNLRYGMKRARPSERRISFERVIELLGIGHL-------LGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEP 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 181 CSALDPISTGRI----EELITELkeDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:TIGR02142 159 LAALDDPRKYEIlpylERLHAEF--GIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPD 224
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
11-221 |
1.17e-27 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 110.49 E-value: 1.17e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYpeQRAEGEILLDGDNI-LTNTQDiAlL 89
Cdd:COG1129 5 LEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKI---LSGVY--QPDSGEILLDGEPVrFRSPRD-A-Q 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFP-MSIYDNIAFGvrlFEKLSRADMDERVQWALTKAALwnetkDKLHQS-------GySLSGGQQQR 161
Cdd:COG1129 78 AAGIAIIHQELNLVPnLSVAENIFLG---REPRRGGLIDWRAMRRRARELL-----ARLGLDidpdtpvG-DLSVAQQQL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 162 LCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDH 221
Cdd:COG1129 149 VEIARALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQgVAIIYISHRLDEVFEIADR 209
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
11-215 |
1.69e-27 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 105.94 E-value: 1.69e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMFELYPEQraEGEILLDGdniltntQDIALLR 90
Cdd:PRK11248 2 LQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLL---NLIAGFVPYQ--HGSITLDG-------KPVEGPG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFP-MSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIA 169
Cdd:PRK11248 70 AERGVVFQNEGLLPwRNVQDNVAFGLQL-AGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQ----LSGGQRQRVGIARALA 144
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQA 215
Cdd:PRK11248 145 ANPQLLLLDEPFGALDAFTREQMQTLLLKLWQETgkQVLLITHDIEEA 192
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
6-242 |
1.94e-27 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 110.30 E-value: 1.94e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 6 TAPGKIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEQraeGEILLDGDNIltNT 83
Cdd:PRK11160 334 ADQVSLTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWD--PQQ---GEILLNGQPI--AD 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 84 QDIALLRAKVGMVFQKPTPFPMSIYDNIAFGvrlfekLSRADmDERVQWALTKAALWNETKDK------LHQSGYSLSGG 157
Cdd:PRK11160 407 YSEAALRQAISVVSQRVHLFSATLRDNLLLA------APNAS-DEALIEVLQQVGLEKLLEDDkglnawLGEGGRQLSGG 479
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 158 QQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHTAFMYLGELIEFSNTD 237
Cdd:PRK11160 480 EQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQNKTVLMITHRLTGLEQF-DRICVMDNGQIIEQGTHQ 558
|
....*
gi 1897751821 238 DLFTK 242
Cdd:PRK11160 559 ELLAQ 563
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
7-243 |
2.28e-27 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 110.33 E-value: 2.28e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 7 APGK--IQVRDL-----------NFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqRAEGEIL 73
Cdd:PRK10261 308 VDGEpiLQVRNLvtrfplrsgllNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVE-----SQGGEII 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 74 LDGDNILT-NTQDIALLRAKVGMVFQKP----TPfPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNEtkdklH 148
Cdd:PRK10261 383 FNGQRIDTlSPGKLQALRRDIQFIFQDPyaslDP-RQTVGDSIMEPLRVHGLLPGKAAAARVAWLLERVGLLPE-----H 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 149 QSGY--SLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTV--VIVTHNMQQAARCSDHTAF 224
Cdd:PRK10261 457 AWRYphEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIayLFISHDMAVVERISHRVAV 536
|
250
....*....|....*....
gi 1897751821 225 MYLGELIEFSNTDDLFTKP 243
Cdd:PRK10261 537 MYLGQIVEIGPRRAVFENP 555
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
11-231 |
2.82e-27 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 104.28 E-value: 2.82e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGDNILTNTQD-IALL 89
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGI--ILPD---SGEVLFDGKPLDIAARNrIGYL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMvFQKptpfpMSIYDNIAFGVRLfEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIA 169
Cdd:cd03269 76 PEERGL-YPK-----MKVIDQLVYLAQL-KGLKKEEARRRIDEWLERLELSEYANKRVEE----LSKGNQQKVQFIAAVI 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:cd03269 145 HDPELLILDEPFSGLDPVNVELLKDVIRELARAgKTVILSTHQMELVEELCDRVLLLNKGRAV 207
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
20-220 |
3.65e-27 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 105.14 E-value: 3.65e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 20 YGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEiLLDGDNILTNTQDiallraKVGMVFQK 99
Cdd:PRK11247 22 YGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGL-----ETPSAGE-LLAGTAPLAEARE------DTRLMFQD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 100 PTPFP-MSIYDNIAFGVRlfeklsrADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLD 178
Cdd:PRK11247 90 ARLLPwKKVIDNVGLGLK-------GQWRDAALQALAAVGL----ADRANEWPAALSGGQKQRVALARALIHRPGLLLLD 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1897751821 179 EPCSALDPIStgRIE--ELITEL--KEDYTVVIVTHNMQQAARCSD 220
Cdd:PRK11247 159 EPLGALDALT--RIEmqDLIESLwqQHGFTVLLVTHDVSEAVAMAD 202
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
9-233 |
4.05e-27 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 104.03 E-value: 4.05e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYYGKF--HALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNIltNTQDI 86
Cdd:cd03369 5 GEIEVENLSVRYAPDlpPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEA-----EEGKIEIDGIDI--STIPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKPTPFPMSIYDNiafgVRLFEKLSradmDERVQWALtkaalwnetkdKLHQSGYSLSGGQQQRLCIAR 166
Cdd:cd03369 78 EDLRSSLTIIPQDPTLFSGTIRSN----LDPFDEYS----DEEIYGAL-----------RVSEGGLNLSQGQRQLLCLAR 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHTAFMYLGELIEF 233
Cdd:cd03369 139 ALLKRPRVLVLDEATASIDYATDALIQKTIREEFTNSTILTIAHRLRTIIDY-DKILVMDAGEVKEY 204
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
11-241 |
7.13e-27 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 104.40 E-value: 7.13e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPEQRAEGEILldgDNILTNTqDIALLR 90
Cdd:COG1119 4 LELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITG--DLPPTYGNDVRLF---GERRGGE-DVWELR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMV---FQKPTPFPMSIYDNI---AFG-VRLFEKLSRADMDERVQWAltkaALWnETKDKLHQSGYSLSGGQQQRLC 163
Cdd:COG1119 78 KRIGLVspaLQLRFPRDETVLDVVlsgFFDsIGLYREPTDEQRERARELL----ELL-GLAHLADRPFGTLSQGEQRRVL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFT 241
Cdd:COG1119 153 IARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGapTLVLVTHHVEEIPPGITHVLLLKDGRVVAAGPKEEVLT 232
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
15-242 |
1.33e-26 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 104.32 E-value: 1.33e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 15 DLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQraeGEILLDGDNILTNTQDIALLRAKVG 94
Cdd:PRK13638 6 DLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGL--LRPQK---GAVLWQGKPLDYSKRGLLALRQQVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 95 MVFQKPTP--FPMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAalwnETKDKLHQSGYSLSGGQQQRLCIARGIAIRP 172
Cdd:PRK13638 81 TVFQDPEQqiFYTDIDSDIAFSLRNL-GVPEAEITRRVDEALTLV----DAQHFRHQPIQCLSHGQKKRVAIAGALVLQA 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 173 EVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:PRK13638 156 RYLLLDEPTAGLDPAGRTQMIAIIRRIvAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFAC 226
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
19-220 |
1.58e-26 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 103.03 E-value: 1.58e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkmfeLYPEQRA-EGEILLDGDNIlTNTQDIALLRAKVGMVF 97
Cdd:PRK11614 14 HYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGT------LCGDPRAtSGRIVFDGKDI-TDWQTAKIMREAVAIVP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 98 QKPTPFP-MSIYDNIAFGVRLFEklsRADMDERVQWALtkaALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLL 176
Cdd:PRK11614 87 EGRRVFSrMTVEENLAMGGFFAE---RDQFQERIKWVY---ELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLL 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1897751821 177 LDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSD 220
Cdd:PRK11614 161 LDEPSLGLAPIIIQQIFDTIEQLREQgMTIFLVEQNANQALKLAD 205
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
11-245 |
1.92e-26 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 102.48 E-value: 1.92e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFelypeQRAEGEILLDGDNIltNTQDIAllr 90
Cdd:TIGR03740 1 LETKNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGIL-----RPTSGEIIFDGHPW--TRKDLH--- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 aKVGMVFQKPTPFP-MSIYDNIAFgVRLFEKLSradmDERVQWALTKAALWNETKDKLHQsgYSLsgGQQQRLCIARGIA 169
Cdd:TIGR03740 71 -KIGSLIESPPLYEnLTARENLKV-HTTLLGLP----DSRIDEVLNIVDLTNTGKKKAKQ--FSL--GMKQRLGIAIALL 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 170 IRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELI------EFSNTDDLFTK 242
Cdd:TIGR03740 141 NHPKLLILDEPTNGLDPIGIQELRELIRSFPEQgITVILSSHILSEVQQLADHIGIISEGVLGyqgkinKSENLEKLFVE 220
|
...
gi 1897751821 243 PAK 245
Cdd:TIGR03740 221 VVK 223
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
10-238 |
3.55e-26 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 103.63 E-value: 3.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 10 KIQVRDLNFYYGK-----FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQrAEGEILLDGDNILTNTQ 84
Cdd:PRK13651 2 QIKVKNIVKIFNKklpteLKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNAL--LLPDT-GTIEWIFKDEKNKKKTK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIAL--------------------LRAKVGMVFQ--KPTPFPMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALwne 142
Cdd:PRK13651 79 EKEKvleklviqktrfkkikkikeIRRRVGVVFQfaEYQLFEQTIEKDIIFGPVSM-GVSKEEAKKRAAKYIELVGL--- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 143 TKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDH 221
Cdd:PRK13651 155 DESYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLnKQGKTIILVTHDLDNVLEWTKR 234
|
250
....*....|....*..
gi 1897751821 222 TAFMYLGELIEFSNTDD 238
Cdd:PRK13651 235 TIFFKDGKIIKDGDTYD 251
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
24-231 |
3.56e-26 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 102.86 E-value: 3.56e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNIlTNTQDIAllRAK-VGMVFQKP-- 100
Cdd:COG1101 20 RALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPP-----DSGSILIDGKDV-TKLPEYK--RAKyIGRVFQDPmm 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 101 -TPFPMSIYDNIA--------FGVRLfeKLSRADMD---ERVqwaltkAALWNETKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:COG1101 92 gTAPSMTIEENLAlayrrgkrRGLRR--GLTKKRRElfrELL------ATLGLGLENRLDTKVGLLSGGQRQALSLLMAT 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:COG1101 164 LTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENnlTTLMVTHNMEQALDYGNRLIMMHEGRII 228
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
11-220 |
6.02e-26 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 101.33 E-value: 6.02e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEqraEGEILLDGDNILTNTQDIalLR 90
Cdd:PRK10247 8 LQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLIS--PT---SGTLLFEGEDISTLKPEI--YR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPFPMSIYDNIAFGVRLFEKlsRADMDeRVQWALTKAALWNETkdkLHQSGYSLSGGQQQRLCIARGIAI 170
Cdd:PRK10247 81 QQVSYCAQTPTLFGDTVYDNLIFPWQIRNQ--QPDPA-IFLDDLERFALPDTI---LTKNIAELSGGEKQRISLIRNLQF 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 171 RPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVI--VTHNMQQAARCSD 220
Cdd:PRK10247 155 MPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVlwVTHDKDEINHADK 206
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
11-243 |
1.40e-25 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 100.96 E-value: 1.40e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPeqrAEGEILLDGDNILT-NTQDIALL 89
Cdd:COG4559 2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTG--ELTP---SSGEVRLNGRPLAAwSPWELARR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAkvgmVFQKPTP--FPMSIYDNIAFGvRLFEKLSRADMDERVQWALTKAALWnetkDKLHQSGYSLSGGQQQRLCIAR- 166
Cdd:COG4559 77 RA----VLPQHSSlaFPFTVEEVVALG-RAPHGSSAAQDRQIVREALALVGLA----HLAGRSYQTLSGGEQQRVQLARv 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 167 ------GIAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL 239
Cdd:COG4559 148 laqlwePVDGGPRWLFLDEPTSALDLAHQHAVLRLARQLaRRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEV 227
|
....
gi 1897751821 240 FTKP 243
Cdd:COG4559 228 LTDE 231
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
20-223 |
1.61e-25 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 99.23 E-value: 1.61e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 20 YGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfnKMFE--LYPeqrAEGEILLDGDniltntqdiallrAKVGMVF 97
Cdd:NF040873 2 YGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLL----KVLAgvLRP---TSGTVRRAGG-------------ARVAYVP 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 98 QK---PTPFPMSIYDNIAFGV----RLFEKLSRADmDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAI 170
Cdd:NF040873 62 QRsevPDSLPLTVRDLVAMGRwarrGLWRRLTRDD-RAAVDDALERVGL----ADLAGRQLGELSGGQRQRALLAQGLAQ 136
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 171 RPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARcSDHTA 223
Cdd:NF040873 137 EADLLLLDEPTTGLDAESRERIIALLAEEHARgATVVVVTHDLELVRR-ADPCV 189
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
11-221 |
2.24e-25 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 100.45 E-value: 2.24e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLlrtFNKMFELYpeQRAEGEILLDGDNI--LTNtQDIAl 88
Cdd:PRK11300 6 LSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTV---FNCLTGFY--KPTGGTILLRGQHIegLPG-HQIA- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 lraKVGMV--FQKPTPF-PMSIYDNI------AFGVRLFEKL------SRADMDervqwALTKAALWNET---KDKLHQS 150
Cdd:PRK11300 79 ---RMGVVrtFQHVRLFrEMTVIENLlvaqhqQLKTGLFSGLlktpafRRAESE-----ALDRAATWLERvglLEHANRQ 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 151 GYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDH 221
Cdd:PRK11300 151 AGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHnvTVLLIEHDMKLVMGISDR 223
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
9-237 |
2.77e-25 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 104.73 E-value: 2.77e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY---GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFEL--------YPEQRAE-------- 69
Cdd:PTZ00265 1164 GKIEIMDVNFRYisrPNVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLkndhhivfKNEHTNDmtneqdyq 1243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 70 ---------------------------------GEILLDGDNILT-NTQDialLRAKVGMVFQKPTPFPMSIYDNIAFGV 115
Cdd:PTZ00265 1244 gdeeqnvgmknvnefsltkeggsgedstvfknsGKILLDGVDICDyNLKD---LRNLFSIVSQEPMLFNMSIYENIKFGK 1320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 116 rlfEKLSRADMDERVQWALTKA---ALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRI 192
Cdd:PTZ00265 1321 ---EDATREDVKRACKFAAIDEfieSLPNKYDTNVGPYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLI 1397
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1897751821 193 EELITELKE--DYTVVIVTHNMQQAARcSDhtafmylgELIEFSNTD 237
Cdd:PTZ00265 1398 EKTIVDIKDkaDKTIITIAHRIASIKR-SD--------KIVVFNNPD 1435
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
11-243 |
2.95e-25 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 100.16 E-value: 2.95e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMFELYPEQraEGEILLDGDNIL-TNTQDIA-- 87
Cdd:COG4604 2 IEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLL---SMISRLLPPD--SGEVLVDGLDVAtTPSRELAkr 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 --LLRakvgmvfQKPTpFPM--SIYDNIAFGvRlF----EKLSRADmDERVQWALTKAALwNETKDK-LHQsgysLSGGQ 158
Cdd:COG4604 77 laILR-------QENH-INSrlTVRELVAFG-R-FpyskGRLTAED-REIIDEAIAYLDL-EDLADRyLDE----LSGGQ 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNT 236
Cdd:COG4604 141 RQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELgkTVVIVLHDINFASCYADHIVAMKDGRVVAQGTP 220
|
....*..
gi 1897751821 237 DDLFTKP 243
Cdd:COG4604 221 EEIITPE 227
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
8-210 |
3.35e-25 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 103.75 E-value: 3.35e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 8 PGKIQVRDLNFYYGKFHA-LKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQraEGEILLDGDNILTNTQdi 86
Cdd:COG5265 355 GGEVRFENVSFGYDPERPiLKGVSFEVPAGKTVAIVGPSGAGKSTLARL---LFRFYDVT--SGRILIDGQDIRDVTQ-- 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKPTPFPMSIYDNIAFGvrlfeklsRADMDERVQWALTKAAlwnetkdKLHQ------SGYS------- 153
Cdd:COG5265 428 ASLRAAIGIVPQDTVLFNDTIAYNIAYG--------RPDASEEEVEAAARAA-------QIHDfieslpDGYDtrvgerg 492
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 154 --LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTH 210
Cdd:COG5265 493 lkLSGGEKQRVAIARTLLKNPPILIFDEATSALDSRTERAIQAALREVARGRTTLVIAH 551
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
30-236 |
8.35e-25 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 98.01 E-value: 8.35e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 30 NLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNILTntqdIALLRAKVGMVFQKPTPFP-MSIY 108
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGF--IEP---ASGSIKVNDQSHTG----LAPYQRPVSMLFQENNLFAhLTVR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 109 DNIAFGVRLFEKLSrADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPIS 188
Cdd:TIGR01277 89 QNIGLGLHPGLKLN-AEQQEKVVDAAQQVGI----ADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1897751821 189 TGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNT 236
Cdd:TIGR01277 164 REEMLALVKQLcsERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVSDC 213
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
26-247 |
2.14e-24 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 98.22 E-value: 2.14e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkmfeLYPEQRAEGEILLDGDNILT-NTQDIALLRAKVGMVFQKP---- 100
Cdd:PRK10419 28 LNNVSLSLKSGETVALLGRSGCGKSTLARLL-----VGLESPSQGNVSWRGEPLAKlNRAQRKAFRRDIQMVFQDSisav 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 101 TPfPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSgysLSGGQQQRLCIARGIAIRPEVLLLDEP 180
Cdd:PRK10419 103 NP-RKTVREIIREPLRHLLSLDKAERLARASEMLRAVDLDDSVLDKRPPQ---LSGGQLQRVCLARALAVEPKLLILDEA 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 181 CSALDPISTGRIEELITELKE--DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDL--FTKPAKKQ 247
Cdd:PRK10419 179 VSNLDLVLQAGVIRLLKKLQQqfGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPVGDKltFSSPAGRV 249
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
5-210 |
2.33e-24 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 101.33 E-value: 2.33e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 5 DTAP---GKIQVRDLNFYYGKFH-ALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMFELYPEQraEGEILLDGDNIL 80
Cdd:PRK10790 332 DDRPlqsGRIDIDNVSFAYRDDNlVLQNINLSVPSRGFVALVGHTGSGKSTLA---SLLMGYYPLT--EGEIRLDGRPLS 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 81 TNTQdiALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLFE-KLSRADmdERVQWALTKAALWNETKDKLHQSGYSLSGGQQ 159
Cdd:PRK10790 407 SLSH--SVLRQGVAMVQQDPVVLADTFLANVTLGRDISEeQVWQAL--ETVQLAELARSLPDGLYTPLGEQGNNLSVGQK 482
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTH 210
Cdd:PRK10790 483 QLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREHTTLVVIAH 533
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
11-231 |
3.56e-24 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 100.49 E-value: 3.56e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfnKMfeLYPEQRA-EGEILLDGDNI-LTNTQDiAL 88
Cdd:COG3845 6 LELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLM----KI--LYGLYQPdSGEILIDGKPVrIRSPRD-AI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 lRAKVGMVFQKPTPFP-MSIYDNIAFGvrlfeklsradMDERVQWALTKAALWNETKDKLHQSG---------YSLSGGQ 158
Cdd:COG3845 79 -ALGIGMVHQHFMLVPnLTVAENIVLG-----------LEPTKGGRLDRKAARARIRELSERYGldvdpdakvEDLSVGE 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPistGRIEELITELK----EDYTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:COG3845 147 QQRVEILKALYRGARILILDEPTAVLTP---QEADELFEILRrlaaEGKSIIFITHKLREVMAIADRVTVLRRGKVV 220
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
25-243 |
5.40e-24 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 98.24 E-value: 5.40e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNIL-TNTQDIALLRAKVGMVFQKP--- 100
Cdd:PRK15079 36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKA-----TDGEVAWLGKDLLgMKDDEWRAVRSDIQMIFQDPlas 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 101 -TPfPMSIYDNIAFGVRLFE-KLSRADMDERVQWALTKAALW-NETKDKLHQsgysLSGGQQQRLCIARGIAIRPEVLLL 177
Cdd:PRK15079 111 lNP-RMTIGEIIAEPLRTYHpKLSRQEVKDRVKAMMLKVGLLpNLINRYPHE----FSGGQCQRIGIARALILEPKLIIC 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 178 DEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKP 243
Cdd:PRK15079 186 DEPVSALDVSIQAQVVNLLQQLQREMglSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNP 253
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
19-217 |
6.80e-24 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 95.71 E-value: 6.80e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNI--LTNtQDIALLRAKVGMV 96
Cdd:PRK10908 11 YLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGI-----ERPSAGKIWFSGHDItrLKN-REVPFLRRQIGMI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 97 FQKP-TPFPMSIYDNIAFGVrLFEKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIAIRPEVL 175
Cdd:PRK10908 85 FQDHhLLMDRTVYDNVAIPL-IIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQ----LSGGEQQRVGIARAVVNKPAVL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1897751821 176 LLDEPCSALDpistGRIEELITELKEDY-----TVVIVTHNMQQAAR 217
Cdd:PRK10908 160 LADEPTGNLD----DALSEGILRLFEEFnrvgvTVLMATHDIGLISR 202
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
13-249 |
7.84e-24 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 99.93 E-value: 7.84e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 13 VRDLNFYY----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDN---ILTNTQD 85
Cdd:PRK10261 15 VENLNIAFmqeqQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSrqvIELSEQS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IALLR----AKVGMVFQKPTP-----FPMSiyDNIAFGVRLFEKLSRADMDERVQWALTKAALwNETKDKLHQSGYSLSG 156
Cdd:PRK10261 95 AAQMRhvrgADMAMIFQEPMTslnpvFTVG--EQIAESIRLHQGASREEAMVEAKRMLDQVRI-PEAQTILSRYPHQLSG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 157 GQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYT--VVIVTHNMQQAARCSDHTAFMYLGELIEFS 234
Cdd:PRK10261 172 GMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSmgVIFITHDMGVVAEIADRVLVMYQGEAVETG 251
|
250
....*....|....*
gi 1897751821 235 NTDDLFTKPAKKQTE 249
Cdd:PRK10261 252 SVEQIFHAPQHPYTR 266
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
26-218 |
1.07e-23 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 95.23 E-value: 1.07e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILT-NTQDIALLRAK-VGMVFQK---- 99
Cdd:PRK10584 26 LTGVELVVKRGETIALIGESGSGKSTLLAILAGL-----DDGSSGEVSLVGQPLHQmDEEARAKLRAKhVGFVFQSfmli 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 100 PTpfpMSIYDNIAFGVrLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDE 179
Cdd:PRK10584 101 PT---LNALENVELPA-LLRGESSRQSRNGAKALLEQLGL----GKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADE 172
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1897751821 180 PCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARC 218
Cdd:PRK10584 173 PTGNLDRQTGDKIADLLFSLNREHgtTLILVTHDLQLAARC 213
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
11-244 |
1.26e-23 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 97.10 E-value: 1.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTllRTFNKMFELYPEQRAEGEILLDGDNILT-NTQD 85
Cdd:PRK09473 13 LDVKDLRVTFstpdGDVTAVNDLNFSLRAGETLGIVGESGSGKSQ--TAFALMGLLAANGRIGGSATFNGREILNlPEKE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IALLRA-KVGMVFQKP----TPFpMSIYDNIAFGVRLFEKLSRAD-MDERVQwaLTKAALWNETKDKLHQSGYSLSGGQQ 159
Cdd:PRK09473 91 LNKLRAeQISMIFQDPmtslNPY-MRVGEQLMEVLMLHKGMSKAEaFEESVR--MLDAVKMPEARKRMKMYPHEFSGGMR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTD 237
Cdd:PRK09473 168 QRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFntAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNAR 247
|
....*..
gi 1897751821 238 DLFTKPA 244
Cdd:PRK09473 248 DVFYQPS 254
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
19-238 |
3.65e-23 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 94.38 E-value: 3.65e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGdniltntqDIA-LLRakVGMVF 97
Cdd:COG1134 35 RREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGI--LEPT---SGRVEVNG--------RVSaLLE--LGAGF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 98 QkptpfP-MSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLL 176
Cdd:COG1134 100 H-----PeLTGRENIYLNGRLL-GLSRKEIDEKFDEIVEFAEL----GDFIDQPVKTYSSGMRARLAFAVATAVDPDILL 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 177 LDEpcsALdpiSTG----------RIEELITELKedyTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDD 238
Cdd:COG1134 170 VDE---VL---AVGdaafqkkclaRIRELRESGR---TVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEE 232
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
9-238 |
7.59e-23 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 97.13 E-value: 7.59e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEQRaeGEILLDGDNILTNTQDi 86
Cdd:COG4618 329 GRLSVENLTVVPpgSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARL---LVGVWPPTA--GSVRLDGADLSQWDRE- 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 aLLRAKVGMVFQKPTPFPMSIYDNIAfgvRLFEklsrADmDERVQWALTKAALwNETKDKLHQ--------SGYSLSGGQ 158
Cdd:COG4618 403 -ELGRHIGYLPQDVELFDGTIAENIA---RFGD----AD-PEKVVAAAKLAGV-HEMILRLPDgydtrigeGGARLSGGQ 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMqQAARCSDHTAFMYLGELIEFSNTD 237
Cdd:COG4618 473 RQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKARgATVVVITHRP-SLLAAVDKLLVLRDGRVQAFGPRD 551
|
.
gi 1897751821 238 D 238
Cdd:COG4618 552 E 552
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
11-217 |
1.46e-22 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 93.15 E-value: 1.46e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQRAEGEILLDGDNILTN---TQDIA 87
Cdd:PRK09984 5 IRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGL--ITGDKSAGSHIELLGRTVQREgrlARDIR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKPTPFP-MSIYDNIAFG-----------VRLFEKLSRadmdERVQWALTKAALWNETkdklHQSGYSLS 155
Cdd:PRK09984 83 KSRANTGYIFQQFNLVNrLSVLENVLIGalgstpfwrtcFSWFTREQK----QRALQALTRVGMVHFA----HQRVSTLS 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 156 GGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED--YTVVIVTHNMQQAAR 217
Cdd:PRK09984 155 GGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdgITVVVTLHQVDYALR 218
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
26-232 |
1.78e-22 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 96.07 E-value: 1.78e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMFELYPEQraeGEILLDGdnILTNTQDIALLRAKVGMVFQKPTPFPM 105
Cdd:PRK11174 366 AGPLNFTLPAGQRIALVGPSGAGKTSLL---NALLGFLPYQ---GSLKING--IELRELDPESWRKHLSWVGQNPQLPHG 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 SIYDNIAFGvrlfeklsRADM-DERVQWALTKAALWNETKDKLH--------QSGySLSGGQQQRLCIARGIAIRPEVLL 176
Cdd:PRK11174 438 TLRDNVLLG--------NPDAsDEQLQQALENAWVSEFLPLLPQgldtpigdQAA-GLSVGQAQRLALARALLQPCQLLL 508
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 177 LDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHTAFMYLGELIE 232
Cdd:PRK11174 509 LDEPTASLDAHSEQLVMQALNAASRRQTTLMVTHQLEDLAQW-DQIWVMQDGQIVQ 563
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
19-240 |
4.06e-22 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 91.49 E-value: 4.06e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKfHALKNINLDIAKNQVTAFIGPSGCGKSTllrTFNKMFELYPeqRAEGEILLDGDniltntqDIALL------RAK 92
Cdd:PRK10895 13 YKGR-RVVEDVSLTVNSGEIVGLLGPNGAGKTT---TFYMVVGIVP--RDAGNIIIDDE-------DISLLplharaRRG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 93 VGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMDERVqwaltkaalwNETKDKLHQS------GYSLSGGQQQRLCIA 165
Cdd:PRK10895 80 IGYLPQEASIFRrLSVYDNLMAVLQIRDDLSAEQREDRA----------NELMEEFHIEhlrdsmGQSLSGGERRRVEIA 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 166 RGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLF 240
Cdd:PRK10895 150 RALAANPKFILLDEPFAGVDPISVIDIKRIIEHLRDSgLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEIL 225
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
30-217 |
5.04e-22 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 90.80 E-value: 5.04e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 30 NLDIAKNQVTAFIGPSGCGKSTLLrtfNKM--FeLYPEQraeGEILLDGDNiLTNTqdiALLRAKVGMVFQKPTPFP-MS 106
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLL---NLIagF-LTPAS---GSLTLNGQD-HTTT---PPSRRPVSMLFQENNLFShLT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 107 IYDNIAFGVRLFEKLSRADMDERVQWAlTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDP 186
Cdd:PRK10771 88 VAQNIGLGLNPGLKLNAAQREKLHAIA-RQMGI----EDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDP 162
|
170 180 190
....*....|....*....|....*....|...
gi 1897751821 187 ISTGRIEELITEL--KEDYTVVIVTHNMQQAAR 217
Cdd:PRK10771 163 ALRQEMLTLVSQVcqERQLTLLMVSHSLEDAAR 195
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
11-257 |
5.90e-22 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 91.77 E-value: 5.90e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLN--FYY--GKFH-----ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPeqrAEGEILLDGDNIlt 81
Cdd:PRK15112 5 LEVRNLSktFRYrtGWFRrqtveAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIE--P---TSGELLIDDHPL-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 82 NTQDIALLRAKVGMVFQKPT----PfPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNEtkdklHQSGYS--LS 155
Cdd:PRK15112 78 HFGDYSYRSQRIRMIFQDPStslnP-RQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGLLPD-----HASYYPhmLA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 156 GGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTV--VIVTHNMQQAARCSDHTAFMYLGELIEF 233
Cdd:PRK15112 152 PGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGIsyIYVTQHLGMMKHISDQVLVMHQGEVVER 231
|
250 260
....*....|....*....|....
gi 1897751821 234 SNTDDLFTKPAKKQTEDYITGRYG 257
Cdd:PRK15112 232 GSTADVLASPLHELTKRLIAGHFG 255
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
24-248 |
1.41e-21 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 93.23 E-value: 1.41e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKST----LLRTFnkmfelypeqRAEGEILLDGDNI-LTNTQDIALLRAKVGMVFQ 98
Cdd:PRK15134 300 VVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI----------NSQGEIWFDGQPLhNLNRRQLLPVRHRIQVVFQ 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 99 KP----TPfPMSIYDNIAFGVRLFEK-LSRADMDERVQWALTKAALWNETKdklHQSGYSLSGGQQQRLCIARGIAIRPE 173
Cdd:PRK15134 370 DPnsslNP-RLNVLQIIEEGLRVHQPtLSAAQREQQVIAVMEEVGLDPETR---HRYPAEFSGGQRQRIAIARALILKPS 445
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 174 VLLLDEPCSALDPISTGRIEELITELKEDYTV--VIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQT 248
Cdd:PRK15134 446 LIILDEPTSSLDKTVQAQILALLKSLQQKHQLayLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYT 522
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
25-246 |
2.20e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 90.05 E-value: 2.20e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQraeGEILLDGdnilTNTQDIALL---RAKVGMVFQKP- 100
Cdd:PRK13644 17 ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGL--LRPQK---GKVLVSG----IDTGDFSKLqgiRKLVGIVFQNPe 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 101 TPF-PMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDE 179
Cdd:PRK13644 88 TQFvGRTVEEDLAFGPENL-CLPPIEIRKRVDRALAEIGL----EKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDE 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 180 PCSALDPISTGRIEELITELKED-YTVVIVTHNMQQaARCSDHTAFMYLGELIEFSNTDDLFTKPAKK 246
Cdd:PRK13644 163 VTSMLDPDSGIAVLERIKKLHEKgKTIVYITHNLEE-LHDADRIIVMDRGKIVLEGEPENVLSDVSLQ 229
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
11-243 |
5.26e-21 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 90.19 E-value: 5.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK----FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElYPEQRAEGEILLDGDNI--LTNTQ 84
Cdd:PRK11022 4 LNVDKLSVHFGDesapFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLID-YPGRVMAEKLEFNGQDLqrISEKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIALLRAKVGMVFQKPTpfpMSIYDNIAFGVRLFEKL------SRADMDERVQWALTKAALwNETKDKLHQSGYSLSGGQ 158
Cdd:PRK11022 83 RRNLVGAEVAMIFQDPM---TSLNPCYTVGFQIMEAIkvhqggNKKTRRQRAIDLLNQVGI-PDPASRLDVYPHQLSGGM 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNT 236
Cdd:PRK11022 159 SQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELqqKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKA 238
|
....*..
gi 1897751821 237 DDLFTKP 243
Cdd:PRK11022 239 HDIFRAP 245
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
27-248 |
5.71e-21 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 88.60 E-value: 5.71e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 27 KNINLDIAKNQVTAFIGPSGCGKSTllrTFNKMFELYPE--QRAEGEILLDGDNILTNTqdialLRAK-VGMVFQKPTPF 103
Cdd:PRK10418 20 HGVSLTLQRGRVLALVGGSGSGKSL---TCAAALGILPAgvRQTAGRVLLDGKPVAPCA-----LRGRkIATIMQNPRSA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 104 PMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWN-ETKDKLHQsgYSLSGGQQQRLCIARGIAIRPEVLLLDEPCS 182
Cdd:PRK10418 92 FNPLHTMHTHARETCLALGKPADDATLTAALEAVGLENaARVLKLYP--FEMSGGMLQRMMIALALLCEAPFIIADEPTT 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 183 ALDPISTGRIEELITELKEDYT--VVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQT 248
Cdd:PRK10418 170 DLDVVAQARILDLLESIVQKRAlgMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVT 237
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
11-211 |
5.75e-21 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 87.20 E-value: 5.75e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkM-FELYPEqrAEGEILLDGDNILT-NTQDIAl 88
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTI--MgHPKYEV--TEGEILFKGEDITDlPPEERA- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 lRAKVGMVFQKPTPFPmsiydniafGVRLfeklsradmdervqwaltkaalwnetKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:cd03217 76 -RLGIFLAFQYPPEIP---------GVKN--------------------------ADFLRYVNEGFSGGEKKRNEILQLL 119
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTHN 211
Cdd:cd03217 120 LLEPDLAILDEPDSGLDIDALRLVAEVINKLReEGKSVLIITHY 163
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
11-213 |
1.57e-20 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 86.62 E-value: 1.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGK-FHALKNINLDIAKNQVTAFIGPSGCGKSTLL-RTFNKMfelypeQRAEGEILLDGDNILTNTQDIAL 88
Cdd:cd03290 1 VQVTNGYFSWGSgLATLSNINIRIPTGQLTMIVGQVGCGKSSLLlAILGEM------QTLEGKVHWSNKNESEPSFEATR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAK--VGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDE-RVQWALTKAALWNETKdkLHQSGYSLSGGQQQRLCIA 165
Cdd:cd03290 75 SRNRysVAYAAQKPWLLNATVEENITFGSPFNKQRYKAVTDAcSLQPDIDLLPFGDQTE--IGERGINLSGGQRQRICVA 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 166 RGIAIRPEVLLLDEPCSALD-PISTGRIEELITELKED--YTVVIVTHNMQ 213
Cdd:cd03290 153 RALYQNTNIVFLDDPFSALDiHLSDHLMQEGILKFLQDdkRTLVLVTHKLQ 203
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
22-225 |
2.35e-20 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 86.33 E-value: 2.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 22 KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkmfeLYPEQRA-EGEILLDGDNILTN-----TQDIALLRAK-VG 94
Cdd:COG4778 23 RLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKC------IYGNYLPdSGSILVRHDGGWVDlaqasPREILALRRRtIG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 95 MVFQkptpF----P-MSIYDNIAfgvrlfEKLSRADMDERVqwALTKAA-----------LWnetkdklHQSGYSLSGGQ 158
Cdd:COG4778 97 YVSQ----FlrviPrVSALDVVA------EPLLERGVDREE--ARARARellarlnlperLW-------DLPPATFSGGE 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVI-VTHNMQQAARCSDHTAFM 225
Cdd:COG4778 158 QQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIgIFHDEEVREAVADRVVDV 225
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
11-243 |
2.47e-20 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 86.81 E-value: 2.47e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPEQRAEGEILLDGDNI----LTNTQDI 86
Cdd:TIGR02323 4 LQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAG--RLAPDHGTATYIMRSGAELelyqLSEAERR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKPTP---FPMSIYDNI-----AFGVRLFEKLSRADMD--ERVQWALTKaalwneTKDKLHQsgysLSG 156
Cdd:TIGR02323 82 RLMRTEWGFVHQNPRDglrMRVSAGANIgerlmAIGARHYGNIRATAQDwlEEVEIDPTR------IDDLPRA----FSG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 157 GQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEFS 234
Cdd:TIGR02323 152 GMQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDLglAVIIVTHDLGVARLLAQRLLVMQQGRVVESG 231
|
....*....
gi 1897751821 235 NTDDLFTKP 243
Cdd:TIGR02323 232 LTDQVLDDP 240
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
10-212 |
2.64e-20 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 90.09 E-value: 2.64e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 10 KIQVRDLNFYYGK---FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqRAEGEILLDGDNiltNTQDI 86
Cdd:PTZ00265 382 KIQFKNVRFHYDTrkdVEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYD-----PTEGDIIINDSH---NLKDI 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 AL--LRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKL-------------SRADMDERVQWALTKAALWNE-----TKDK 146
Cdd:PTZ00265 454 NLkwWRSKIGVVSQDPLLFSNSIKNNIKYSLYSLKDLealsnyynedgndSQENKNKRNSCRAKCAGDLNDmsnttDSNE 533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 147 LHQ---------------------------------------SGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPI 187
Cdd:PTZ00265 534 LIEmrknyqtikdsevvdvskkvlihdfvsalpdkyetlvgsNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNK 613
|
250 260
....*....|....*....|....*..
gi 1897751821 188 STGRIEELITELK--EDYTVVIVTHNM 212
Cdd:PTZ00265 614 SEYLVQKTINNLKgnENRITIIIAHRL 640
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
26-217 |
7.17e-20 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 88.63 E-value: 7.17e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNkmfelYPEQRAEGEILLDGDNILT-NTQDIALLRAK-VGMVFQKPTPF 103
Cdd:PRK10535 24 LKGISLDIYAGEMVAIVGASGSGKSTLMNILG-----CLDKPTSGTYRVAGQDVATlDADALAQLRREhFGFIFQRYHLL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 104 P-MSIYDNIAFGVrLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCS 182
Cdd:PRK10535 99 ShLTAAQNVEVPA-VYAGLERKQRLLRAQELLQRLGL----EDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTG 173
|
170 180 190
....*....|....*....|....*....|....*....
gi 1897751821 183 ALDPISTgriEELITELKE----DYTVVIVTHNMQQAAR 217
Cdd:PRK10535 174 ALDSHSG---EEVMAILHQlrdrGHTVIIVTHDPQVAAQ 209
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
12-237 |
7.91e-20 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 85.75 E-value: 7.91e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPEQraeGEILLDG-DNILTNTQDIA--- 87
Cdd:PRK11701 8 SVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSA--RLAPDA---GEVHYRMrDGQLRDLYALSeae 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 ---LLRAKVGMVFQKPTP---FPMSIYDNI-----AFGVRLFEKLSRADMD--ERVQWALtkaalwnetkDKLHQSGYSL 154
Cdd:PRK11701 83 rrrLLRTEWGFVHQHPRDglrMQVSAGGNIgerlmAVGARHYGDIRATAGDwlERVEIDA----------ARIDDLPTTF 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 155 SGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIE 232
Cdd:PRK11701 153 SGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELglAVVIVTHDLAVARLLAHRLLVMKQGRVVE 232
|
....*
gi 1897751821 233 FSNTD 237
Cdd:PRK11701 233 SGLTD 237
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
28-249 |
8.40e-20 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 88.22 E-value: 8.40e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 28 NINLDIAKNQVTAFIGPSGCGKS----TLLRTFNKMFELYPEqraeGEILLDGDNIL-TNTQDIALLRA-KVGMVFQKPT 101
Cdd:PRK15134 27 DVSLQIEAGETLALVGESGSGKSvtalSILRLLPSPPVVYPS----GDIRFHGESLLhASEQTLRGVRGnKIAMIFQEPM 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 102 pfpMSIYDNIAFGVRLFEKLS----------RADMD---ERVqwALTKAAlwNETKDKLHQsgysLSGGQQQRLCIARGI 168
Cdd:PRK15134 103 ---VSLNPLHTLEKQLYEVLSlhrgmrreaaRGEILnclDRV--GIRQAA--KRLTDYPHQ----LSGGERQRVMIAMAL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKE--DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKK 246
Cdd:PRK15134 172 LTRPELLIADEPTTALDVSVQAQILQLLRELQQelNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPTHP 251
|
...
gi 1897751821 247 QTE 249
Cdd:PRK15134 252 YTQ 254
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
26-210 |
1.47e-19 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 83.37 E-value: 1.47e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfeLYPEQRAEGEILLDGDNIltntqDIALLRAKVGMVFQkptpfpm 105
Cdd:cd03213 25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAG---RRTGLGVSGEVLINGRPL-----DKRSFRKIIGYVPQ------- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 siyDNIafgvrLFEKLSradmderVQWALTKAAlwnetkdKLHqsgySLSGGQQQRLCIARGIAIRPEVLLLDEPCSALD 185
Cdd:cd03213 90 ---DDI-----LHPTLT-------VRETLMFAA-------KLR----GLSGGERKRVSIALELVSNPSLLFLDEPTSGLD 143
|
170 180
....*....|....*....|....*.
gi 1897751821 186 PISTGRIEELITEL-KEDYTVVIVTH 210
Cdd:cd03213 144 SSSALQVMSLLRRLaDTGRTIICSIH 169
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
20-233 |
1.87e-19 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 83.74 E-value: 1.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 20 YGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGdniltntQDIALLRAKVGMVFQk 99
Cdd:cd03220 32 VGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGI--YPPD---SGTVTVRG-------RVSSLLGLGGGFNPE- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 100 ptpfpMSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDE 179
Cdd:cd03220 99 -----LTGRENIYLNGRLL-GLSRKEIDEKIDEIIEFSEL----GDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDE 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 180 PCSALDPISTGRIEELITELKEDY-TVVIVTHNMQQAARCSDHTAFMYLGELIEF 233
Cdd:cd03220 169 VLAVGDAAFQEKCQRRLRELLKQGkTVILVSHDPSSIKRLCDRALVLEKGKIRFD 223
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
11-220 |
3.23e-19 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 86.05 E-value: 3.23e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPeqrAEGEILLDGDNIlTNTQDIALLR 90
Cdd:PRK09536 4 IDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGT--LTP---TAGTVLVAGDDV-EALSARAASR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 aKVGMVFQKPT-PFPMSIYDNIAFGVRlfEKLSRAD-MDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:PRK09536 78 -RVASVPQDTSlSFEFDVRQVVEMGRT--PHRSRFDtWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARAL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSD 220
Cdd:PRK09536 155 AQATPVLLLDEPTASLDINHQVRTLELVRRLVDDgKTAVAAIHDLDLAARYCD 207
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
12-211 |
1.06e-18 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 82.42 E-value: 1.06e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkM-FELYpeQRAEGEILLDGDNILT-NTQDIAll 89
Cdd:COG0396 2 EIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVL--MgHPKY--EVTSGSILLDGEDILElSPDERA-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFP-MSIYD--NIAFGVRLFEKLSRADMDERVQwalTKAALWNETKDKLHQS-GYSLSGGQQQRLCIA 165
Cdd:COG0396 76 RAGIFLAFQYPVEIPgVSVSNflRTALNARRGEELSAREFLKLLK---EKMKELGLDEDFLDRYvNEGFSGGEKKRNEIL 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1897751821 166 RGIAIRPEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTHN 211
Cdd:COG0396 153 QMLLLEPKLAILDETDSGLDIDALRIVAEGVNKLRsPDRGILIITHY 199
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
11-239 |
1.18e-18 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 85.18 E-value: 1.18e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfnKMFE-LYPEqrAEGEILLDGDNIltNTQDIAlL 89
Cdd:NF033858 267 IEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTM----KMLTgLLPA--SEGEAWLFGQPV--DAGDIA-T 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKptpFpmSIY------DNIAFGVRLFEkLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLC 163
Cdd:NF033858 338 RRRVGYMSQA---F--SLYgeltvrQNLELHARLFH-LPAAEIAARVAEMLERFDL----ADVADALPDSLPLGIRQRLS 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCsDHTAFMYLG---------ELIE 232
Cdd:NF033858 408 LAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELsrEDGVTIFISTHFMNEAERC-DRISLMHAGrvlasdtpaALVA 486
|
....*..
gi 1897751821 233 FSNTDDL 239
Cdd:NF033858 487 ARGAATL 493
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
6-221 |
2.46e-18 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 82.55 E-value: 2.46e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 6 TAPgkIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEQraeGEILLDGDNILTNTQd 85
Cdd:PRK13537 5 VAP--IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGL--THPDA---GSISLCGEPVPSRAR- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 iaLLRAKVGMVFQKPTPFP-MSIYDNIAFGVRLFeKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQQQRLCI 164
Cdd:PRK13537 77 --HARQRVGVVPQFDNLDPdFTVRENLLVFGRYF-GLSAAAARALVPPLLEFAKLENKADAKVGE----LSGGMKRRLTL 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 165 ARGIAIRPEVLLLDEPCSALDPISTGRI-EELITELKEDYTVVIVTHNMQQAARCSDH 221
Cdd:PRK13537 150 ARALVNDPDVLVLDEPTTGLDPQARHLMwERLRSLLARGKTILLTTHFMEEAERLCDR 207
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
26-241 |
2.74e-18 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 81.04 E-value: 2.74e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMFELYPeqrAEGEILLDGDNILT-NTQDIALLRAKVGMvfQKPTPFP 104
Cdd:COG4138 12 LGPISAQVNAGELIHLIGPNGAGKSTLL---ARMAGLLP---GQGEILLNGRPLSDwSAAELARHRAYLSQ--QQSPPFA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 105 MSIYDNIAFGVrlfEKLSRADMDERVQWALTkAALwnETKDKLHQSGYSLSGGQQQRLCIARGI-----AIRPE--VLLL 177
Cdd:COG4138 84 MPVFQYLALHQ---PAGASSEAVEQLLAQLA-EAL--GLEDKLSRPLTQLSGGEWQRVRLAAVLlqvwpTINPEgqLLLL 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 178 DEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFT 241
Cdd:COG4138 158 DEPMNSLDVAQQAALDRLLRELCQQgITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMT 222
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
9-239 |
2.77e-18 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 84.23 E-value: 2.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqRAEGEILLDGDNIltntQDI 86
Cdd:TIGR00957 1283 GRVEFRNYCLRYreDLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINE-----SAEGEIIIDGLNI----AKI 1353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 AL--LRAKVGMVFQKPTPFPMSIYDNIafgvRLFEKLSradmDERVQWALTKAALW---NETKDKL-HQ---SGYSLSGG 157
Cdd:TIGR00957 1354 GLhdLRFKITIIPQDPVLFSGSLRMNL----DPFSQYS----DEEVWWALELAHLKtfvSALPDKLdHEcaeGGENLSVG 1425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 158 QQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAArcsDHTAFMYL--GELIEFSN 235
Cdd:TIGR00957 1426 QRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIM---DYTRVIVLdkGEVAEFGA 1502
|
....
gi 1897751821 236 TDDL 239
Cdd:TIGR00957 1503 PSNL 1506
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
9-218 |
3.71e-18 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 81.44 E-value: 3.71e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqrAEGEILLDGDNilTNTQDI 86
Cdd:cd03289 1 GQMTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN------TEGDIQIDGVS--WNSVPL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKptpfpmsiydniafgVRLFEKLSRADMDERVQWalTKAALWNETKD----------------KLHQS 150
Cdd:cd03289 73 QKWRKAFGVIPQK---------------VFIFSGTFRKNLDPYGKW--SDEEIWKVAEEvglksvieqfpgqldfVLVDG 135
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 151 GYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARC 218
Cdd:cd03289 136 GCVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQVIRKTLKQAFADCTVILSEHRIEAMLEC 203
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
25-230 |
5.82e-18 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 83.14 E-value: 5.82e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTllrTFNKMFELYPEqrAEGEILLDGDNILTNtqdIALLRAKVGMVFQKPTPFP 104
Cdd:TIGR01257 945 AVDRLNITFYENQITAFLGHNGAGKTT---TLSILTGLLPP--TSGTVLVGGKDIETN---LDAVRQSLGMCPQHNILFH 1016
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 105 -MSIYDNIAFgvrlFEKLSRADMDERvqwALTKAALWNET--KDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPC 181
Cdd:TIGR01257 1017 hLTVAEHILF----YAQLKGRSWEEA---QLEMEAMLEDTglHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPT 1089
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1897751821 182 SALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGEL 230
Cdd:TIGR01257 1090 SGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRL 1138
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
21-242 |
1.01e-17 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 82.01 E-value: 1.01e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 21 GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPEqrAEGEILLDGDNIltNTQDIALLRAKVGMVFQKP 100
Cdd:TIGR01842 329 GKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARL---IVGIWPP--TSGSVRLDGADL--KQWDRETFGKHIGYLPQDV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 101 TPFPMSIYDNIAfgvRLFEKlsrADMDERVQWAltKAALWNETKDKLHQsGY---------SLSGGQQQRLCIARGIAIR 171
Cdd:TIGR01842 402 ELFPGTVAENIA---RFGEN---ADPEKIIEAA--KLAGVHELILRLPD-GYdtvigpggaTLSGGQRQRIALARALYGD 472
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 172 PEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTHNMqQAARCSDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:TIGR01842 473 PKLVVLDEPNSNLDEEGEQALANAIKALKaRGITVVVITHRP-SLLGCVDKILVLQDGRIARFGERDEVLAK 543
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
12-230 |
1.02e-17 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 78.24 E-value: 1.02e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYygkfHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPeqRAEGEILLDGDNILTNTQDIALlRA 91
Cdd:cd03215 6 EVRGLSVK----GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEA---LFGLRP--PASGEITLDGKPVTRRSPRDAI-RA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 92 KVGMVfqkptP--------FP-MSIYDNIAFGVRLfeklsradmdervqwaltkaalwnetkdklhqsgyslSGGQQQRL 162
Cdd:cd03215 76 GIAYV-----PedrkreglVLdLSVAENIALSSLL-------------------------------------SGGNQQKV 113
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 163 CIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGEL 230
Cdd:cd03215 114 VLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAgKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
6-210 |
1.30e-17 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 81.78 E-value: 1.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 6 TAPGKIQVRDLNFYYGKFHAL-KNINLDIAKNQVTAFIGPSGCGKSTLLRTFNkmfELYPeqRAEGEILL-DGDNILtnt 83
Cdd:COG4178 358 SEDGALALEDLTLRTPDGRPLlEDLSLSLKPGERLLITGPSGSGKSTLLRAIA---GLWP--YGSGRIARpAGARVL--- 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 84 qdiallrakvgmvF--QKPtpfpmsiYdnIAFGvRLFEKLSRADM-----DERVQWALTKAALwNETKDKLHQS---GYS 153
Cdd:COG4178 430 -------------FlpQRP-------Y--LPLG-TLREALLYPATaeafsDAELREALEAVGL-GHLAERLDEEadwDQV 485
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 154 LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTH 210
Cdd:COG4178 486 LSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLREELPGTTVISVGH 542
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
26-231 |
1.34e-17 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 78.85 E-value: 1.34e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPeqRAEGEILLDGDNIltntqDIALLRAKVGMVFQKPTPFP- 104
Cdd:cd03234 23 LNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGG--TTSGQILFNGQPR-----KPDQFQKCVAYVRQDDILLPg 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 105 MSIYDNIAFGV--RLFEKLSRADMDERV------QWALTKAAlwnetkdklHQSGYSLSGGQQQRLCIARGIAIRPEVLL 176
Cdd:cd03234 96 LTVRETLTYTAilRLPRKSSDAIRKKRVedvllrDLALTRIG---------GNLVKGISGGERRRVSIAVQLLWDPKVLI 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 177 LDEPCSALDPISTGRIEELITELKEDYTVVIVT-HnmQQAA---RCSDHTAFMYLGELI 231
Cdd:cd03234 167 LDEPTSGLDSFTALNLVSTLSQLARRNRIVILTiH--QPRSdlfRLFDRILLLSSGEIV 223
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
8-210 |
1.42e-17 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 81.68 E-value: 1.42e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 8 PGKIQVRDLNFYYGKFH--ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNIltntQD 85
Cdd:PRK10789 311 RGELDVNIRQFTYPQTDhpALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDV-----SEGDIRFHDIPL----TK 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 86 IAL--LRAKVGMVFQKPTPFPMSIYDNIAFGvrlfeklsRAD-MDERVQWAltkAALWNETKDKLH----------QSGY 152
Cdd:PRK10789 382 LQLdsWRSRLAVVSQTPFLFSDTVANNIALG--------RPDaTQQEIEHV---ARLASVHDDILRlpqgydtevgERGV 450
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1897751821 153 SLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDpistGRIEELI----TELKEDYTVVIVTH 210
Cdd:PRK10789 451 MLSGGQKQRISIARALLLNAEILILDDALSAVD----GRTEHQIlhnlRQWGEGRTVIISAH 508
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
12-231 |
1.75e-17 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 79.45 E-value: 1.75e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGdNILTNTQDIALLRA 91
Cdd:PRK10575 13 ALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRH-----QPPSEGEILLDA-QPLESWSSKAFARK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 92 KVGMVFQKPTPFPMSIYDNIAFGVRLFE----KLSRADMdERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARG 167
Cdd:PRK10575 87 VAYLPQQLPAAEGMTVRELVAIGRYPWHgalgRFGAADR-EKVEEAISLVGL----KPLAHRLVDSLSGGERQRAWIAML 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 168 IAIRPEVLLLDEPCSALDPISTGRIEELITELKED--YTVVIVTHNMQQAARCSDHTAFMYLGELI 231
Cdd:PRK10575 162 VAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQErgLTVIAVLHDINMAARYCDYLVALRGGEMI 227
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
11-231 |
2.41e-17 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 78.53 E-value: 2.41e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY--------------GKFH-------ALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfnKMFE--LYPEQr 67
Cdd:cd03267 1 IEVSNLSKSYrvyskepgligslkSLFKrkyreveALKGISFTIEKGEIVGFIGPNGAGKTTTL----KILSglLQPTS- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 68 aeGEILLDGdnILTNTQDIALLRaKVGMVF-QKPTpfpmSIYD-NIAFGVRLFEKLSRADmDERVQWALTKAALWNETKD 145
Cdd:cd03267 76 --GEVRVAG--LVPWKRRKKFLR-RIGVVFgQKTQ----LWWDlPVIDSFYLLAAIYDLP-PARFKKRLDELSELLDLEE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 146 KLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTA 223
Cdd:cd03267 146 LLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERgtTVLLTSHYMKDIEALARRVL 225
|
....*...
gi 1897751821 224 FMYLGELI 231
Cdd:cd03267 226 VIDKGRLL 233
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
21-219 |
2.54e-17 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 78.32 E-value: 2.54e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 21 GKFHA--LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGD--NILTNTQDIALLRAKVGMV 96
Cdd:PRK11629 18 GSVQTdvLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGL-----DTPTSGDVIFNGQpmSKLSSAAKAELRNQKLGFI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 97 FQKPTPFP-MSIYDNIAFGVrLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVL 175
Cdd:PRK11629 93 YQFHHLLPdFTALENVAMPL-LIGKKKPAEINSRALEMLAAVGL----EHRANHRPSELSGGERQRVAIARALVNNPRLV 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1897751821 176 LLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQQAARCS 219
Cdd:PRK11629 168 LADEPTGNLDARNADSIFQLLGELnrLQGTAFLVVTHDLQLAKRMS 213
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
26-211 |
4.01e-17 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 77.22 E-value: 4.01e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNILTNT--QDIALLRAKVGMvfqKPTpf 103
Cdd:PRK13539 18 FSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPP-----AAGTIKLDGGDIDDPDvaEACHYLGHRNAM---KPA-- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 104 pMSIYDNIAFGVRLfeklsRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSA 183
Cdd:PRK13539 88 -LTVAENLEFWAAF-----LGGEELDIAAALEAVGL----APLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAA 157
|
170 180
....*....|....*....|....*....
gi 1897751821 184 LDPISTGRIEELITE-LKEDYTVVIVTHN 211
Cdd:PRK13539 158 LDAAAVALFAELIRAhLAQGGIVIAATHI 186
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
9-218 |
5.31e-17 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 80.34 E-value: 5.31e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqrAEGEILLDGdnILTNTQDI 86
Cdd:TIGR01271 1216 GQMDVQGLTAKYteAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS------TEGEIQIDG--VSWNSVTL 1287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKptpfpmsiydniafgVRLFEKLSRADMDERVQWalTKAALWNETK------------DKLH----QS 150
Cdd:TIGR01271 1288 QTWRKAFGVIPQK---------------VFIFSGTFRKNLDPYEQW--SDEEIWKVAEevglksvieqfpDKLDfvlvDG 1350
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 151 GYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARC 218
Cdd:TIGR01271 1351 GYVLSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQIIRKTLKQSFSNCTVILSEHRVEALLEC 1418
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
11-239 |
8.16e-17 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 79.46 E-value: 8.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY-----GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPeqrAEGEI-LLDGDNILTNTQ 84
Cdd:TIGR03269 280 IKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLE--P---TSGEVnVRVGDEWVDMTK 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIALLRAKV----GMVFQKPTPFP-MSIYDNI--AFGVRLFEKLSRadmdERVQWALtKAALWNETKDK--LHQSGYSLS 155
Cdd:TIGR03269 355 PGPDGRGRAkryiGILHQEYDLYPhRTVLDNLteAIGLELPDELAR----MKAVITL-KMVGFDEEKAEeiLDKYPDELS 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 156 GGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQQAARCSDHTAFMYLGELIEF 233
Cdd:TIGR03269 430 EGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEMeqTFIIVSHDMDFVLDVCDRAALMRDGKIVKI 509
|
....*.
gi 1897751821 234 SNTDDL 239
Cdd:TIGR03269 510 GDPEEI 515
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
11-241 |
2.16e-16 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 76.46 E-value: 2.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFH-ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEIlldgdNILTNTQDIALL 89
Cdd:PRK15056 7 IVVNDVTVTWRNGHtALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRL-----ASGKI-----SILGQPTRQALQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPT---PFPMSIYDNIA---FGVRLFEKLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLC 163
Cdd:PRK15056 77 KNLVAYVPQSEEvdwSFPVLVEDVVMmgrYGHMGWLRRAKKRDRQIVTAALARVDM----VEFRHRQIGELSGGQKKRVF 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTHNMQQAARCSDHTAfMYLGELIEFSNTDDLFT 241
Cdd:PRK15056 153 LARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRdEGKTMLVSTHNLGSVTEFCDYTV-MVKGTVLASGPTETTFT 230
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
11-210 |
2.86e-16 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 73.25 E-value: 2.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGdniltntqdiallR 90
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPD-----EGIVTWGS-------------T 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQkptpfpmsiydniafgvrlfeklsradmdervqwaltkaalwnetkdklhqsgysLSGGQQQRLCIARGIAI 170
Cdd:cd03221 63 VKIGYFEQ-------------------------------------------------------LSGGEKMRLALAKLLLE 87
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1897751821 171 RPEVLLLDEPCSALDPIStgrIEELITELKEDY-TVVIVTH 210
Cdd:cd03221 88 NPNLLLLDEPTNHLDLES---IEALEEALKEYPgTVILVSH 125
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
11-239 |
3.81e-16 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 77.47 E-value: 3.81e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfnkmfELYPEQRA--EGEI-LLDGDniLTNTQDIA 87
Cdd:NF033858 2 ARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLL-------SLIAGARKiqQGRVeVLGGD--MADARHRR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQ---K---PTpfpMSIYDNIAFGVRLFeKLSRADMDERVQwALTKAalwnetkdklhqSGYS-------- 153
Cdd:NF033858 73 AVCPRIAYMPQglgKnlyPT---LSVFENLDFFGRLF-GQDAAERRRRID-ELLRA------------TGLApfadrpag 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 154 -LSGGQQQR--LCIArgiAIR-PEVLLLDEPCSALDPISTGRIEELITELKED---YTVVIVTHNMQQAARCsDHTAFMY 226
Cdd:NF033858 136 kLSGGMKQKlgLCCA---LIHdPDLLILDEPTTGVDPLSRRQFWELIDRIRAErpgMSVLVATAYMEEAERF-DWLVAMD 211
|
250 260
....*....|....*....|..
gi 1897751821 227 LG---------ELIEFSNTDDL 239
Cdd:NF033858 212 AGrvlatgtpaELLARTGADTL 233
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
28-244 |
5.48e-16 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 76.07 E-value: 5.48e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 28 NINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMFELYPEQraEGEILLdGDNILTNT-QDIALL--RAKVGMVFQKPTPFP 104
Cdd:PRK11144 16 TVNLTLPAQGITAIFGRSGAGKTSLI---NAISGLTRPQ--KGRIVL-NGRVLFDAeKGICLPpeKRRIGYVFQDARLFP 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 105 -MSIYDNIAFGVRlfeKLSRADMDERVQwALTKAALwnetkdkLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSA 183
Cdd:PRK11144 90 hYKVRGNLRYGMA---KSMVAQFDKIVA-LLGIEPL-------LDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLAS 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 184 LD-PistgRIEELITELKE-----DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPA 244
Cdd:PRK11144 159 LDlP----RKRELLPYLERlareiNIPILYVSHSLDEILRLADRVVVLEQGKVKAFGPLEEVWASSA 221
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
22-210 |
6.90e-16 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 74.22 E-value: 6.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 22 KFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRtfnKMFELYPEQRAEGEILLDGDNIltnTQDIALLRAkvgmvfqkpt 101
Cdd:COG2401 42 ERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLR---LLAGALKGTPVAGCVDVPDNQF---GREASLIDA---------- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 102 pfpMSIYDNIAFGVRLfekLSRAdmdervqwALTKAALWnetKDKLHQsgysLSGGQQQRLCIARGIAIRPEVLLLDEPC 181
Cdd:COG2401 106 ---IGRKGDFKDAVEL---LNAV--------GLSDAVLW---LRRFKE----LSTGQKFRFRLALLLAERPKLLVIDEFC 164
|
170 180 190
....*....|....*....|....*....|...
gi 1897751821 182 SALDPISTGR----IEELITELKEdyTVVIVTH 210
Cdd:COG2401 165 SHLDRQTAKRvarnLQKLARRAGI--TLVVATH 195
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
9-242 |
1.34e-15 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 74.17 E-value: 1.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYYGKF--HALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEILLDGDNIltNTQDI 86
Cdd:cd03288 18 GEIKIHDLCVRYENNlkPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIF-----DGKIVIDGIDI--SKLPL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 87 ALLRAKVGMVFQKPTPFPMSIYDNIafgvrlfeKLSRADMDERVQWALTKAALWNETKD-------KLHQSGYSLSGGQQ 159
Cdd:cd03288 91 HTLRSRLSIILQDPILFSGSIRFNL--------DPECKCTDDRLWEALEIAQLKNMVKSlpggldaVVTEGGENFSVGQR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARcSDHTAFMYLGELIEFSNTDDL 239
Cdd:cd03288 163 QLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVSTILD-ADLVLVLSRGILVECDTPENL 241
|
...
gi 1897751821 240 FTK 242
Cdd:cd03288 242 LAQ 244
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
5-237 |
1.72e-15 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 75.44 E-value: 1.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 5 DTAPGKI--QVRDLNfyygKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPeqRAEGEILLDGDNI-LT 81
Cdd:COG1129 249 AAAPGEVvlEVEGLS----VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARA---LFGADP--ADSGEIRLDGKPVrIR 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 82 NTQD-----IALL---RAKVGMVFqkptpfPMSIYDNIAFGVrlFEKLSRAD-MDERVQWALTKAALwnetkDKL----- 147
Cdd:COG1129 320 SPRDairagIAYVpedRKGEGLVL------DLSIRENITLAS--LDRLSRGGlLDRRRERALAEEYI-----KRLriktp 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 148 --HQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPcsaldpisTgR---------IEELITEL-KEDYTVVIVTHNMQQA 215
Cdd:COG1129 387 spEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEP--------T-RgidvgakaeIYRLIRELaAEGKAVIVISSELPEL 457
|
250 260
....*....|....*....|...
gi 1897751821 216 ARCSDHTAFMYLGELI-EFSNTD 237
Cdd:COG1129 458 LGLSDRILVMREGRIVgELDREE 480
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
13-210 |
3.89e-15 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 74.33 E-value: 3.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 13 VRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPEqraEGEILLDGDniltntqdiallrAK 92
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAG--ELEPD---SGEVSIPKG-------------LR 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 93 VGMVFQKPTPFP-MSIYDNIAFGV-RLFEKLSR------------ADMDE--RVQWALTKAALWN-ETK----------- 144
Cdd:COG0488 63 IGYLPQEPPLDDdLTVLDTVLDGDaELRALEAEleeleaklaepdEDLERlaELQEEFEALGGWEaEARaeeilsglgfp 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 145 -DKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDpISTgrIEELITELKE-DYTVVIVTH 210
Cdd:COG0488 143 eEDLDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLD-LES--IEWLEEFLKNyPGTVLVVSH 207
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
26-244 |
5.31e-15 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 72.55 E-value: 5.31e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFelyPEQ------RAEGEILLDGDNILT-NTQDIALLRAkvgMVFQ 98
Cdd:PRK13547 17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDL---TGGgaprgaRVTGDVTLNGEPLAAiDAPRLARLRA---VLPQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 99 KPTP-FPMSIYDNIAFG----VRLFEKLSRADMDerVQWaltkAALWNETKDKL-HQSGYSLSGGQQQRLCIARGIA--- 169
Cdd:PRK13547 91 AAQPaFAFSAREIVLLGryphARRAGALTHRDGE--IAW----QALALAGATALvGRDVTTLSGGELARVQFARVLAqlw 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 170 ------IRPEVLLLDEPCSALDPISTGRIEELITELKEDYT--VVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFT 241
Cdd:PRK13547 165 pphdaaQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNlgVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVLT 244
|
...
gi 1897751821 242 kPA 244
Cdd:PRK13547 245 -PA 246
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
25-220 |
1.14e-14 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 73.02 E-value: 1.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFelypeQRAEGEILLDGDNI-LTNTQDIalLRAKVGMVFQKPTPF 103
Cdd:PRK11288 19 ALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNY-----QPDAGSILIDGQEMrFASTTAA--LAAGVAIIYQELHLV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 104 P-MSIYDNIAFGvRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYsLSGGQQQRLCIARGIAIRPEVLLLDEPCS 182
Cdd:PRK11288 92 PeMTVAENLYLG-QLPHKGGIVNRRLLNYEAREQLEHLGVDIDPDTPLKY-LSIGQRQMVEIAKALARNARVIAFDEPTS 169
|
170 180 190
....*....|....*....|....*....|....*....
gi 1897751821 183 ALDPISTGRIEELITELKEDYTVVI-VTHNMQQAARCSD 220
Cdd:PRK11288 170 SLSAREIEQLFRVIRELRAEGRVILyVSHRMEEIFALCD 208
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
26-217 |
2.04e-14 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 72.64 E-value: 2.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPeqrAEGEILLDGdniltntqdiallraKVGMVFQKPTPFPM 105
Cdd:TIGR01271 442 LKNISFKLEKGQLLAVAGSTGSGKSSLLMMI--MGELEP---SEGKIKHSG---------------RISFSPQTSWIMPG 501
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 SIYDNIAFGVRlFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALD 185
Cdd:TIGR01271 502 TIKDNIIFGLS-YDEYRYTSVIKACQLEEDIALFPEKDKTVLGEGGITLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
|
170 180 190
....*....|....*....|....*....|...
gi 1897751821 186 PISTGRI-EELITELKEDYTVVIVTHNMQQAAR 217
Cdd:TIGR01271 581 VVTEKEIfESCLCKLMSNKTRILVTSKLEHLKK 613
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
11-242 |
3.02e-14 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 71.76 E-value: 3.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEqraEGEIL----------------- 73
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYEPT---SGRIIyhvalcekcgyverpsk 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 74 --------------LDGDNILTNTQDIALLRAKVGMVFQKPtpfpMSIYDNIAFGVRLFEKLSRADM--DERVQWALTka 137
Cdd:TIGR03269 78 vgepcpvcggtlepEEVDFWNLSDKLRRRIRKRIAIMLQRT----FALYGDDTVLDNVLEALEEIGYegKEAVGRAVD-- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 138 aLWNETK--DKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL--KEDYTVVIVTHNMQ 213
Cdd:TIGR03269 152 -LIEMVQlsHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAvkASGISMVLTSHWPE 230
|
250 260
....*....|....*....|....*....
gi 1897751821 214 QAARCSDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:TIGR03269 231 VIEDLSDKAIWLENGEIKEEGTPDEVVAV 259
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
6-254 |
3.20e-14 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 71.62 E-value: 3.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 6 TAPGKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNI--LTNT 83
Cdd:PRK15439 7 TAPPLLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGI-----VPPDSGTLEIGGNPCarLTPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 84 QDIALlraKVGMVFQKPTPFP-MSIYDNIAFGVRlfeklSRADMDERVQWALtkAALwnETKDKLHQSGYSLSGGQQQRL 162
Cdd:PRK15439 82 KAHQL---GIYLVPQEPLLFPnLSVKENILFGLP-----KRQASMQKMKQLL--AAL--GCQLDLDSSAGSLEVADRQIV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 163 CIARGIAIRPEVLLLDEPCSALDPIST----GRIEELiteLKEDYTVVIVTHNMQQAARCSDHTAFM-----YLGELIEF 233
Cdd:PRK15439 150 EILRGLMRDSRILILDEPTASLTPAETerlfSRIREL---LAQGVGIVFISHKLPEIRQLADRISVMrdgtiALSGKTAD 226
|
250 260
....*....|....*....|.
gi 1897751821 234 SNTDDLFTKPAKKQTEDYITG 254
Cdd:PRK15439 227 LSTDDIIQAITPAAREKSLSA 247
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
24-213 |
3.89e-14 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 70.50 E-value: 3.89e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfnKMFE--LYPEqraEGEILLDGDNIltNTQDIALLRaKVGMVF-QK- 99
Cdd:COG4586 36 EAVDDISFTIEPGEIVGFIGPNGAGKSTTI----KMLTgiLVPT---SGEVRVLGYVP--FKRRKEFAR-RIGVVFgQRs 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 100 ------PT--PFPM--SIYDniafgvrlfekLSRADMDERVQWaLTKaALwnETKDKLHQSGYSLSGGQQQRLCIArgiA 169
Cdd:COG4586 106 qlwwdlPAidSFRLlkAIYR-----------IPDAEYKKRLDE-LVE-LL--DLGELLDTPVRQLSLGQRMRCELA---A 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1897751821 170 I---RPEVLLLDEPCSALDPISTGRIEELITELKEDY--TVVIVTHNMQ 213
Cdd:COG4586 168 AllhRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERgtTILLTSHDMD 216
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-220 |
7.65e-14 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 69.86 E-value: 7.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 1 MSMVDTApgkIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPEqraEGEILLDGDNIL 80
Cdd:PRK13536 35 GSMSTVA---IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTS--PD---AGKITVLGVPVP 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 81 TNTQdiaLLRAKVGMVFQKPTPFP-MSIYDN-IAFGvRLFeKLSRADMDERVQWALTKAALWNETKDKLHQsgysLSGGQ 158
Cdd:PRK13536 107 ARAR---LARARIGVVPQFDNLDLeFTVRENlLVFG-RYF-GMSTREIEAVIPSLLEFARLESKADARVSD----LSGGM 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRI-EELITELKEDYTVVIVTHNMQQAARCSD 220
Cdd:PRK13536 178 KRRLTLARALINDPQLLILDEPTTGLDPHARHLIwERLRSLLARGKTILLTTHFMEEAERLCD 240
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
9-242 |
8.14e-14 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 70.78 E-value: 8.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 9 GKIQVRDLNFYY--GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNI----LTN 82
Cdd:PLN03232 1233 GSIKFEDVHLRYrpGLPPVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVEL-----EKGRIMIDDCDVakfgLTD 1307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 83 tqdialLRAKVGMVFQKPTPFPMSIydniAFGVRLFEKLSRADMDERVQWALTKAALWNET---KDKLHQSGYSLSGGQQ 159
Cdd:PLN03232 1308 ------LRRVLSIIPQSPVLFSGTV----RFNIDPFSEHNDADLWEALERAHIKDVIDRNPfglDAEVSEGGENFSVGQR 1377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHTAFMYLGELIEFSNTDDL 239
Cdd:PLN03232 1378 QLLSLARALLRRSKILVLDEATASVDVRTDSLIQRTIREEFKSCTMLVIAHRLNTIIDC-DKILVLSSGQVLEYDSPQEL 1456
|
...
gi 1897751821 240 FTK 242
Cdd:PLN03232 1457 LSR 1459
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
11-252 |
8.24e-14 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 70.62 E-value: 8.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfeLYPEQRAEGEILLDGDNIL-TNTQDIAll 89
Cdd:TIGR02633 2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSG---VYPHGTWDGEIYWSGSPLKaSNIRDTE-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVGMVFQKPTPFP-MSIYDNIAFGVRLFEKLSRADMDERVQWAltkAALWNETK---DKLHQSGYSLSGGQQQRLCIA 165
Cdd:TIGR02633 77 RAGIVIIHQELTLVPeLSVAENIFLGNEITLPGGRMAYNAMYLRA---KNLLRELQldaDNVTRPVGDYGGGQQQLVEIA 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 166 RGIAIRPEVLLLDEPCSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARCSDHTAFMYLGELIEfsntddlfTKPA 244
Cdd:TIGR02633 154 KALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAhGVACVYISHKLNEVKAVCDTICVIRDGQHVA--------TKDM 225
|
....*...
gi 1897751821 245 KKQTEDYI 252
Cdd:TIGR02633 226 STMSEDDI 233
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
11-210 |
9.71e-14 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 70.09 E-value: 9.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPEqraEGEILLdGDNILTN--TQDIAL 88
Cdd:COG0488 316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLL--AGELEPD---SGTVKL-GETVKIGyfDQHQEE 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKvgmvfqkptpfpMSIYDNIafgvrlfeklSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:COG0488 390 LDPD------------KTVLDEL----------RDGAPGGTEQEVRGYLGRFLFSGDDAFKPVGVLSGGEKARLALAKLL 447
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 1897751821 169 AIRPEVLLLDEPCSALDPIStgrIEELiTELKEDY--TVVIVTH 210
Cdd:COG0488 448 LSPPNVLLLDEPTNHLDIET---LEAL-EEALDDFpgTVLLVSH 487
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
11-237 |
3.97e-13 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 68.66 E-value: 3.97e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElyPeqrAEGEILLDGDNILTNTQDIAlLR 90
Cdd:PRK09700 6 ISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHE--P---TKGTITINNINYNKLDHKLA-AQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMVFQKPTPF-PMSIYDNIAFGVRLFEK------LSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLC 163
Cdd:PRK09700 80 LGIGIIYQELSVIdELTVLENLYIGRHLTKKvcgvniIDWREMRVRAAMMLLRVGL----KVDLDEKVANLSISHKQMLE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 164 IARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYT-VVIVTHNMQQAARCSDHTAFM------YLGELIEFSNT 236
Cdd:PRK09700 156 IAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTaIVYISHKLAEIRRICDRYTVMkdgssvCSGMVSDVSND 235
|
.
gi 1897751821 237 D 237
Cdd:PRK09700 236 D 236
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
21-252 |
4.38e-13 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 67.91 E-value: 4.38e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 21 GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNI-LTNTQDIALLRAKVGMVFQK 99
Cdd:PRK15093 18 GWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDNWRVTADRMRFDDIDLLrLSPRERRKLVGHNVSMIFQE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 100 PtpfpMSIYD-NIAFGVRLFEKLS----RADMDERVQWALTKAALW------NETKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:PRK15093 98 P----QSCLDpSERVGRQLMQNIPgwtyKGRWWQRFGWRKRRAIELlhrvgiKDHKDAMRSFPYELTEGECQKVMIAIAL 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKED--YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKK 246
Cdd:PRK15093 174 ANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNnnTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTPHHP 253
|
....*.
gi 1897751821 247 QTEDYI 252
Cdd:PRK15093 254 YTQALI 259
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
41-243 |
6.71e-13 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 66.49 E-value: 6.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 41 FIGPSGCGKSTLLRTFNKMFElypeqrAEGEILLDGDNILTNTQ-DIALLRAKVGMvfQKPTPFPMSIYDNIAfgvrlfe 119
Cdd:PRK03695 27 LVGPNGAGKSTLLARMAGLLP------GSGSIQFAGQPLEAWSAaELARHRAYLSQ--QQTPPFAMPVFQYLT------- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 120 kLSRADM--DERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGI-----AIRPE--VLLLDEPCSALDPISTG 190
Cdd:PRK03695 92 -LHQPDKtrTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVlqvwpDINPAgqLLLLDEPMNSLDVAQQA 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 191 RIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKP 243
Cdd:PRK03695 171 ALDRLLSELCQQgIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPE 224
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
26-234 |
1.17e-12 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 67.50 E-value: 1.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDgdniltntQDIAllrakvgMVFQKPTPFPM 105
Cdd:PTZ00243 676 LRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEI-----SEGRVWAE--------RSIA-------YVPQQAWIMNA 735
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 SIYDNIAFgvrlFEKLSRADMDERVQ-------WALTKAALWNETKDKlhqsGYSLSGGQQQRLCIARGIAIRPEVLLLD 178
Cdd:PTZ00243 736 TVRGNILF----FDEEDAARLADAVRvsqleadLAQLGGGLETEIGEK----GVNLSGGQKARVSLARAVYANRDVYLLD 807
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 179 EPCSALDPISTGRI-EELITELKEDYTVVIVTHNMQQAARcSDHTAFMYLGElIEFS 234
Cdd:PTZ00243 808 DPLSALDAHVGERVvEECFLGALAGKTRVLATHQVHVVPR-ADYVVALGDGR-VEFS 862
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
26-217 |
1.32e-12 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 66.03 E-value: 1.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPeqrAEGEILLDGdniltntqdiallraKVGMVFQKPTPFPM 105
Cdd:cd03291 53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLI--LGELEP---SEGKIKHSG---------------RISFSSQFSWIMPG 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 SIYDNIAFGVrlfeklsraDMDERVQWALTKAALWNE------TKDK--LHQSGYSLSGGQQQRLCIARGIAIRPEVLLL 177
Cdd:cd03291 113 TIKENIIFGV---------SYDEYRYKSVVKACQLEEditkfpEKDNtvLGEGGITLSGGQRARISLARAVYKDADLYLL 183
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1897751821 178 DEPCSALDPISTGRI-EELITELKEDYTVVIVTHNMQQAAR 217
Cdd:cd03291 184 DSPFGYLDVFTEKEIfESCVCKLMANKTRILVTSKMEHLKK 224
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
13-210 |
1.42e-12 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 64.69 E-value: 1.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 13 VRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfeLYPEqraEGEILLDGDNILTN----TQDIAL 88
Cdd:TIGR01189 3 ARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGL--LRPD---SGEVRWNGTPLAEQrdepHENILY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKVGMvfqKPTpfpMSIYDNIAFGVRLFEKLSRADMDervqwALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:TIGR01189 78 LGHLPGL---KPE---LSALENLHFWAAIHGGAQRTIED-----ALAAVGL----TGFEDLPAAQLSAGQQRRLALARLW 142
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITE-LKEDYTVVIVTH 210
Cdd:TIGR01189 143 LSRRPLWILDEPTTALDKAGVALLAGLLRAhLARGGIVLLTTH 185
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
11-210 |
1.47e-12 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 65.43 E-value: 1.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfnKMFELYPE-QRAEGEILLDGDNILTNTQDIall 89
Cdd:CHL00131 8 LEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLS----KVIAGHPAyKILEGDILFKGESILDLEPEE--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 90 RAKVG--MVFQKPTPFPMsiYDNIAF------GVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQS---GYslSGGQ 158
Cdd:CHL00131 81 RAHLGifLAFQYPIEIPG--VSNADFlrlaynSKRKFQGLPELDPLEFLEIINEKLKLVGMDPSFLSRNvneGF--SGGE 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTH 210
Cdd:CHL00131 157 KKRNEILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMtSENSIILITH 209
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
4-237 |
1.51e-12 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 66.57 E-value: 1.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 4 VDTAPGKI--QVRDLNfyyGKfhALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPeqRAEGEILLDGDNILT 81
Cdd:PRK10762 249 LDKAPGEVrlKVDNLS---GP--GVNDVSFTLRKGEILGVSGLMGAGRTELMKV---LYGALP--RTSGYVTLDGHEVVT 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 82 NT-QD-----IALL---RAKVGMVFQkptpfpMSIYDNIAF-GVRLFEKLS-RADMDERVQWALTKAALWNETKDKLHQS 150
Cdd:PRK10762 319 RSpQDglangIVYIsedRKRDGLVLG------MSVKENMSLtALRYFSRAGgSLKHADEQQAVSDFIRLFNIKTPSMEQA 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 151 GYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGE 229
Cdd:PRK10762 393 IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEgLSIILVSSEMPEVLGMSDRILVMHEGR 472
|
....*....
gi 1897751821 230 LI-EFSNTD 237
Cdd:PRK10762 473 ISgEFTREQ 481
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
25-252 |
1.81e-12 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 66.49 E-value: 1.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfeLYPEQRAEGEILLDGDNI-LTNTQDIAllRAKVGMVFQKPTPF 103
Cdd:PRK13549 20 ALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSG---VYPHGTYEGEIIFEGEELqASNIRDTE--RAGIAIIHQELALV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 104 P-MSIYDNIAFGVRLfEKLSRADMDERVQWAltkAALWNETKDKL--HQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEP 180
Cdd:PRK13549 95 KeLSVLENIFLGNEI-TPGGIMDYDAMYLRA---QKLLAQLKLDInpATPVGNLGLGQQQLVEIAKALNKQARLLILDEP 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 181 CSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARCSDHTAFMYLGELIEfsntddlfTKPAKKQTEDYI 252
Cdd:PRK13549 171 TASLTESETAVLLDIIRDLKAhGIACIYISHKLNEVKAISDTICVIRDGRHIG--------TRPAAGMTEDDI 235
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
26-210 |
2.36e-12 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 63.33 E-value: 2.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYpeqraEGEI-LLDGDNILtntqdiallrakvgMVFQKPtpfp 104
Cdd:cd03223 17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWG-----SGRIgMPEGEDLL--------------FLPQRP---- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 105 msiYdnIAFGvRLFEKLSRAdmdervqwaltkaalWNETkdklhqsgysLSGGQQQRLCIARGIAIRPEVLLLDEPCSAL 184
Cdd:cd03223 74 ---Y--LPLG-TLREQLIYP---------------WDDV----------LSGGEQQRLAFARLLLHKPKFVFLDEATSAL 122
|
170 180
....*....|....*....|....*.
gi 1897751821 185 DPISTGRIEELITELKedYTVVIVTH 210
Cdd:cd03223 123 DEESEDRLYQLLKELG--ITVISVGH 146
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
12-239 |
6.88e-12 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 64.81 E-value: 6.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYygKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMFELYPeqRAEGEILLDGDNILTNTQDIALlra 91
Cdd:PRK09700 267 EVRNVTSR--DRKKVRDISFSVCRGEILGFAGLVGSGRTELM---NCLFGVDK--RAGGEIRLNGKDISPRSPLDAV--- 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 92 KVGMVF----QKPTPF--PMSIYDNIAFGVRLfeKLSR--------ADMDERvQWALTKAALWNETKDKLHQSGYSLSGG 157
Cdd:PRK09700 337 KKGMAYitesRRDNGFfpNFSIAQNMAISRSL--KDGGykgamglfHEVDEQ-RTAENQRELLALKCHSVNQNITELSGG 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 158 QQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIE-FSN 235
Cdd:PRK09700 414 NQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDgKVILMVSSELPEIITVCDRIAVFCEGRLTQiLTN 493
|
....
gi 1897751821 236 TDDL 239
Cdd:PRK09700 494 RDDM 497
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
11-212 |
7.07e-12 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 64.97 E-value: 7.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFH--ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkmfeLYPEQRAEGEILLDGdniltntqdial 88
Cdd:TIGR00957 637 ITVHNATFTWARDLppTLNGITFSIPEGALVAVVGQVGCGKSSLLSAL-----LAEMDKVEGHVHMKG------------ 699
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 lraKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMdERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:TIGR00957 700 ---SVAYVPQQAWIQNDSLRENILFGKALNEKYYQQVL-EACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAV 775
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELIT---ELKEDYTVVIVTHNM 212
Cdd:TIGR00957 776 YSNADIYLFDDPLSAVDAHVGKHIFEHVIgpeGVLKNKTRILVTHGI 822
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
26-242 |
2.43e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 63.60 E-value: 2.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNILTntQDIALLRAKVGMVFQKPTPFPM 105
Cdd:PLN03130 1255 LHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVEL-----ERGRILIDGCDISK--FGLMDLRKVLGIIPQAPVLFSG 1327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 SIydniAFGVRLFEKLSRADMDERVQWALTKAALWNETKD---KLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCS 182
Cdd:PLN03130 1328 TV----RFNLDPFNEHNDADLWESLERAHLKDVIRRNSLGldaEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEATA 1403
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 183 ALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCsDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:PLN03130 1404 AVDVRTDALIQKTIREEFKSCTMLIIAHRLNTIIDC-DRILVLDAGRVVEFDTPENLLSN 1462
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
26-240 |
2.91e-11 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 63.26 E-value: 2.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeqrAEGEILLDGDNIltNTQDIALLRAKVGMVFQKPTPFPM 105
Cdd:PTZ00243 1326 LRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEV-----CGGEIRVNGREI--GAYGLRELRRQFSMIPQDPVLFDG 1398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 SIYDNI-----AFGVRLFEKLSRADMDERVqwaltkaALWNETKD-KLHQSGYSLSGGQQQRLCIARGIAIRPE-VLLLD 178
Cdd:PTZ00243 1399 TVRQNVdpfleASSAEVWAALELVGLRERV-------ASESEGIDsRVLEGGSNYSVGQRQLMCMARALLKKGSgFILMD 1471
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 179 EPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCS-----DHTAFMYLG---ELIEfsNTDDLF 240
Cdd:PTZ00243 1472 EATANIDPALDRQIQATVMSAFSAYTVITIAHRLHTVAQYDkiivmDHGAVAEMGsprELVM--NRQSIF 1539
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
24-221 |
4.05e-11 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 61.12 E-value: 4.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTLL---------RTFNKMFELYPEQRAEGEILLDGDNILTNTQDIAL------ 88
Cdd:cd03270 9 HNLKNVDVDIPRNKLVVITGVSGSGKSSLAfdtiyaegqRRYVESLSAYARQFLGQMDKPDVDSIEGLSPAIAIdqktts 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 --LRAKVGMVfqkptpfpMSIYDNIAFgvrLFeklSRADMDERVQWaLTKAALWNETkdkLHQSGYSLSGGQQQRLCIAR 166
Cdd:cd03270 89 rnPRSTVGTV--------TEIYDYLRL---LF---ARVGIRERLGF-LVDVGLGYLT---LSRSAPTLSGGEAQRIRLAT 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 167 GIAIR-PEVL-LLDEPCSALDPISTGRIEELITELKE-DYTVVIVTHNmQQAARCSDH 221
Cdd:cd03270 151 QIGSGlTGVLyVLDEPSIGLHPRDNDRLIETLKRLRDlGNTVLVVEHD-EDTIRAADH 207
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
11-185 |
5.54e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 62.45 E-value: 5.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYY---GKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPeqRAEGEILLdgdniltntqdia 87
Cdd:PLN03130 615 ISIKNGYFSWdskAERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAM--LGELPP--RSDASVVI------------- 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 llRAKVGMVFQKPTPFPMSIYDNIAFGvrlfeklsrADMD-ERVQWALTKAALWNETK-------DKLHQSGYSLSGGQQ 159
Cdd:PLN03130 678 --RGTVAYVPQVSWIFNATVRDNILFG---------SPFDpERYERAIDVTALQHDLDllpggdlTEIGERGVNISGGQK 746
|
170 180
....*....|....*....|....*.
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALD 185
Cdd:PLN03130 747 QRVSMARAVYSNSDVYIFDDPLSALD 772
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
26-210 |
6.21e-11 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 61.89 E-value: 6.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNkmfelypeqraeGEILLDgDNILTNTQDIALLRAKvgmvfQKPtpfPM 105
Cdd:PRK11147 19 LDNAELHIEDNERVCLVGRNGAGKSTLMKILN------------GEVLLD-DGRIIYEQDLIVARLQ-----QDP---PR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 ----SIYDNIAFGV-------RLFEKLSRADMDE----------RVQWALTKAALW---NETKDKLHQSGY-------SL 154
Cdd:PRK11147 78 nvegTVYDFVAEGIeeqaeylKRYHDISHLVETDpseknlnelaKLQEQLDHHNLWqleNRINEVLAQLGLdpdaalsSL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 155 SGGQQQRLCIARGIAIRPEVLLLDEPCSALDpISTgrIEELITELKeDY--TVVIVTH 210
Cdd:PRK11147 158 SGGWLRKAALGRALVSNPDVLLLDEPTNHLD-IET--IEWLEGFLK-TFqgSIIFISH 211
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
25-254 |
2.98e-10 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 59.74 E-value: 2.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYpeQRAEGEILLDGDNILTNTQDIAlLRAKVGMVFQKPTPF- 103
Cdd:PRK10982 13 ALDNVNLKVRPHSIHALMGENGAGKSTLLKC---LFGIY--QKDSGSILFQGKEIDFKSSKEA-LENGISMVHQELNLVl 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 104 PMSIYDNIAFGvRLFEKLSRADMDErvqwaltkaaLWNETK---DKL------HQSGYSLSGGQQQRLCIARGIAIRPEV 174
Cdd:PRK10982 87 QRSVMDNMWLG-RYPTKGMFVDQDK----------MYRDTKaifDELdididpRAKVATLSVSQMQMIEIAKAFSYNAKI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 175 LLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEfsntddlfTKPAKKQTEDYIT 253
Cdd:PRK10982 156 VIMDEPTSSLTEKEVNHLFTIIRKLKERgCGIVYISHKMEEIFQLCDEITILRDGQWIA--------TQPLAGLTMDKII 227
|
.
gi 1897751821 254 G 254
Cdd:PRK10982 228 A 228
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
19-210 |
4.24e-10 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 59.56 E-value: 4.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 19 YYGKFHALKNINLDI---AKNQVtafIGPSGCGKSTLLRTfnkMFELypEQRAEGEILLDGDniltntqdiallrAKVGM 95
Cdd:TIGR03719 14 VPPKKEILKDISLSFfpgAKIGV---LGLNGAGKSTLLRI---MAGV--DKDFNGEARPQPG-------------IKVGY 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 96 VFQKPTPFP-MSIYDNIAFGVR-----------LFEKLSR--ADMDE------RVQWALTKAALWN-ETK-----DKLH- 148
Cdd:TIGR03719 73 LPQEPQLDPtKTVRENVEEGVAeikdaldrfneISAKYAEpdADFDKlaaeqaELQEIIDAADAWDlDSQleiamDALRc 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 149 ----QSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEdyTVVIVTH 210
Cdd:TIGR03719 153 ppwdADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEYPG--TVVAVTH 216
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
24-209 |
6.49e-10 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 58.91 E-value: 6.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPEQRAEGEILLDGDNIltntqDIALLRAKVGMVFQKPTPF 103
Cdd:TIGR00955 39 HLLKNVSGVAKPGELLAVMGSSGAGKTTLMNAL--AFRSPKGVKGSGSVLLNGMPI-----DAKEMRAISAYVQQDDLFI 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 104 PM-SIYDNIAFG--VRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGY--SLSGGQQQRLCIARGIAIRPEVLLLD 178
Cdd:TIGR00955 112 PTlTVREHLMFQahLRMPRRVTKKEKRERVDEVLQALGLRKCANTRIGVPGRvkGLSGGERKRLAFASELLTDPPLLFCD 191
|
170 180 190
....*....|....*....|....*....|.
gi 1897751821 179 EPCSALDPISTGRIEELITELKEDYTVVIVT 209
Cdd:TIGR00955 192 EPTSGLDSFMAYSVVQVLKGLAQKGKTIICT 222
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
26-210 |
1.04e-09 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 56.73 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNILTNTQDIAllRAKVGMVFQKPTPFPM 105
Cdd:cd03231 16 FSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGL-----SPPLAGRVLLNGGPLDFQRDSIA--RGLLYLGHAPGIKTTL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 SIYDNIAFgvrlfekLSRADMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALD 185
Cdd:cd03231 89 SVLENLRF-------WHADHSDEQVEEALARVGL----NGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALD 157
|
170 180
....*....|....*....|....*.
gi 1897751821 186 PISTGRIEELIT-ELKEDYTVVIVTH 210
Cdd:cd03231 158 KAGVARFAEAMAgHCARGGMVVLTTH 183
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
26-185 |
1.17e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 58.45 E-value: 1.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPEQRAEgeilldgdniltntqdiALLRAKVGMVFQKPTPFPM 105
Cdd:PLN03232 633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAM--LGELSHAETSS-----------------VVIRGSVAYVPQVSWIFNA 693
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 SIYDNIAFGVRlFEKlsradmdERVQWALTKAALWNE-------TKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLD 178
Cdd:PLN03232 694 TVRENILFGSD-FES-------ERYWRAIDVTALQHDldllpgrDLTEIGERGVNISGGQKQRVSMARAVYSNSDIYIFD 765
|
....*..
gi 1897751821 179 EPCSALD 185
Cdd:PLN03232 766 DPLSALD 772
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
11-221 |
1.42e-09 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 57.72 E-value: 1.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLL--------RTFNKMFELYPEQRAEGEILLDgdnIltn 82
Cdd:PRK10938 261 IVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLslitgdhpQGYSNDLTLFGRRRGSGETIWD---I--- 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 83 TQDIALLRAKVGMVFQKPTpfpmSIYDNIAFG----VRLFEKLSRADMDERVQWaLTKAALWNETKDKLHQSgysLSGGQ 158
Cdd:PRK10938 335 KKHIGYVSSSLHLDYRVST----SVRNVILSGffdsIGIYQAVSDRQQKLAQQW-LDILGIDKRTADAPFHS---LSWGQ 406
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPIStgR------IEELITElkEDYTVVIVTHNMQQAARCSDH 221
Cdd:PRK10938 407 QRLALIVRALVKHPTLLILDEPLQGLDPLN--RqlvrrfVDVLISE--GETQLLFVSHHAEDAPACITH 471
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
25-236 |
1.91e-09 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 57.43 E-value: 1.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFElypeqRAEGEILLDGDNILTNTQDIALL---------RAKVGM 95
Cdd:PRK10982 263 SIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIRE-----KSAGTITLHGKKINNHNANEAINhgfalvteeRRSTGI 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 96 VFQKPTPFPmSIYDNIAFGVRLFEKLSRADMDERVQWALTKAalwnETKDKLHQSGY-SLSGGQQQRLCIARGIAIRPEV 174
Cdd:PRK10982 338 YAYLDIGFN-SLISNIRNYKNKVGLLDNSRMKSDTQWVIDSM----RVKTPGHRTQIgSLSGGNQQKVIIGRWLLTQPEI 412
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1897751821 175 LLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNT 236
Cdd:PRK10982 413 LMLDEPTRGIDVGAKFEIYQLIAELaKKDKGIIIISSEMPELLGITDRILVMSNGLVAGIVDT 475
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
11-210 |
2.39e-09 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 56.34 E-value: 2.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELypeQRAEGEILLDGDNILTNTQDialLR 90
Cdd:PRK09580 2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDY---EVTGGTVEFKGKDLLELSPE---DR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVG--MVFQKPTPFP-------MSIYDNIAFGVRLFEKLSRADMDERVQwalTKAALWNETKDKLHQS-GYSLSGGQQQ 160
Cdd:PRK09580 76 AGEGifMAFQYPVEIPgvsnqffLQTALNAVRSYRGQEPLDRFDFQDLME---EKIALLKMPEDLLTRSvNVGFSGGEKK 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 161 RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELK-EDYTVVIVTH 210
Cdd:PRK09580 153 RNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRdGKRSFIIVTH 203
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
25-222 |
2.41e-09 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 57.11 E-value: 2.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLlrtfnkMFEL---YPEQRAEGEILLDGD-------------NILTNTQDIAL 88
Cdd:NF040905 16 ALDDVNLSVREGEIHALCGENGAGKSTL------MKVLsgvYPHGSYEGEILFDGEvcrfkdirdsealGIVIIHQELAL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LrakvgmvfqkptPFpMSIYDNIAFGvrlFEKLSRADMDervqWALTkaalWNETKDKLHQSGYSLS--------G-GQQ 159
Cdd:NF040905 90 I------------PY-LSIAENIFLG---NERAKRGVID----WNET----NRRARELLAKVGLDESpdtlvtdiGvGKQ 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 160 QRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARCSDHT 222
Cdd:NF040905 146 QLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLELKAqGITSIIISHKLNEIRRVADSI 209
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
25-224 |
2.90e-09 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 56.94 E-value: 2.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 25 ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFelypeQRAEGEILLDGDNILTN----TQDiallrAKVGMVFQKP 100
Cdd:PRK10762 19 ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIY-----TRDAGSILYLGKEVTFNgpksSQE-----AGIGIIHQEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 101 TPFP-MSIYDNIAFGVRLFEKLSRADMDERVQWA---LTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLL 176
Cdd:PRK10762 89 NLIPqLTIAENIFLGREFVNRFGRIDWKKMYAEAdklLARLNL----RFSSDKLVGELSIGEQQMVEIAKVLSFESKVII 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1897751821 177 LDEPCSALDPISTGRIEELITELK-EDYTVVIVTHNMQQAAR-CSDHTAF 224
Cdd:PRK10762 165 MDEPTDALTDTETESLFRVIRELKsQGRGIVYISHRLKEIFEiCDDVTVF 214
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
28-230 |
3.43e-09 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 56.76 E-value: 3.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 28 NINLDIAKNQVTAFIGPSGCGKSTLLRTfnkMFELYPeQRAEGEILLDGDNILTNTQDIALlRAKVGMV---FQKPTPFP 104
Cdd:TIGR02633 278 DVSFSLRRGEILGVAGLVGAGRTELVQA---LFGAYP-GKFEGNVFINGKPVDIRNPAQAI-RAGIAMVpedRKRHGIVP 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 105 -MSIYDNIAFGV-RLFEKLSRADmDERVQWALTKAAlwnetkDKLHQSGYS-------LSGGQQQRLCIARGIAIRPEVL 175
Cdd:TIGR02633 353 iLGVGKNITLSVlKSFCFKMRID-AAAELQIIGSAI------QRLKVKTASpflpigrLSGGNQQKAVLAKMLLTNPRVL 425
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 176 LLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGEL 230
Cdd:TIGR02633 426 ILDEPTRGVDVGAKYEIYKLINQLaQEGVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
2-242 |
3.75e-09 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 56.28 E-value: 3.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 2 SMVDTAPGKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTllrtfnkmfELYPEQRAEGEILLDGDNILT 81
Cdd:NF000106 5 TISNGARNAVEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**R---------GALPAHV*GPDAGRRPWRF*T 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 82 NTQDIALLRAKVGMvfQKPTPF----PMSIYDN---IAFGVRLFEKLSRADMDERVQ-WALTKAAlwnetkdklHQSGYS 153
Cdd:NF000106 76 WCANRRALRRTIG*--HRPVR*grreSFSGRENlymIGR*LDLSRKDARARADELLErFSLTEAA---------GRAAAK 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 154 LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRI-EELITELKEDYTVVIVTHNMQQAARCSDHTAFMYLGELIE 232
Cdd:NF000106 145 YSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVwDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIA 224
|
250
....*....|
gi 1897751821 233 FSNTDDLFTK 242
Cdd:NF000106 225 DGKVDELKTK 234
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
14-185 |
4.29e-09 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 54.56 E-value: 4.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 14 RDLNFY----YGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkmfelypEQRA-----EGEILLDGDNIltntq 84
Cdd:cd03232 7 KNLNYTvpvkGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVL--------AGRKtagviTGEILINGRPL----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 85 DIALLRaKVGMVFQKPTPFPMSIydniafgVR---LFEKLSRAdmdervqwaltkaalwnetkdklhqsgysLSGGQQQR 161
Cdd:cd03232 74 DKNFQR-STGYVEQQDVHSPNLT-------VRealRFSALLRG-----------------------------LSVEQRKR 116
|
170 180
....*....|....*....|....
gi 1897751821 162 LCIARGIAIRPEVLLLDEPCSALD 185
Cdd:cd03232 117 LTIGVELAAKPSILFLDEPTSGLD 140
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
6-201 |
5.92e-09 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 55.80 E-value: 5.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 6 TAPGKI--QVRDLNFY-YGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTfnkmfeLYPEQRAE-GEILLDGDNIlT 81
Cdd:COG3845 251 AEPGEVvlEVENLSVRdDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEA------LAGLRPPAsGSIRLDGEDI-T 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 82 NtQDIALLRA-----------KVGMVfqkPTpfpMSIYDNIAFGVRLFEKLSRA---DMDERVQWALTKAALWNETKDKL 147
Cdd:COG3845 324 G-LSPRERRRlgvayipedrlGRGLV---PD---MSVAENLILGRYRRPPFSRGgflDRKAIRAFAEELIEEFDVRTPGP 396
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 148 HQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKE 201
Cdd:COG3845 397 DTPARSLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRD 450
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
20-212 |
7.87e-09 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 54.73 E-value: 7.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 20 YGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkmfeLYPEQRAEGEILLDGdniltntqdiallRAKVGMVFQK 99
Cdd:PRK09544 14 FGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVV-----LGLVAPDEGVIKRNG-------------KLRIGYVPQK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 100 ----PT-PFPMSIYDNIAFGVRlfeklsRADMD---ERVQwaltKAALWNETKDKLhqsgyslSGGQQQRLCIARGIAIR 171
Cdd:PRK09544 76 lyldTTlPLTVNRFLRLRPGTK------KEDILpalKRVQ----AGHLIDAPMQKL-------SGGETQRVLLARALLNR 138
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1897751821 172 PEVLLLDEPCSALDPISTGRIEELITELKE--DYTVVIVTHNM 212
Cdd:PRK09544 139 PQLLVLDEPTQGVDVNGQVALYDLIDQLRRelDCAVLMVSHDL 181
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
28-210 |
1.29e-08 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 53.65 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 28 NINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIltNTQDIALLRA------KVGMvfqKP- 100
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGL-----ARPDAGEVLWQGEPI--RRQRDEYHQDllylghQPGI---KTe 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 101 -TPFpmsiyDNIAFGVRLFEKLSradmDERVQWALTKAALwnetkdklhqSGY------SLSGGQQQRLCIARGIAIRPE 173
Cdd:PRK13538 89 lTAL-----ENLRFYQRLHGPGD----DEALWEALAQVGL----------AGFedvpvrQLSAGQQRRVALARLWLTRAP 149
|
170 180 190
....*....|....*....|....*....|....*...
gi 1897751821 174 VLLLDEPCSALDPISTGRIEELITE-LKEDYTVVIVTH 210
Cdd:PRK13538 150 LWILDEPFTAIDKQGVARLEALLAQhAEQGGMVILTTH 187
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
11-215 |
6.40e-08 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 51.17 E-value: 6.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFyygkfHALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMFElypeqrAEGEILLDGDniltntqdiallr 90
Cdd:cd03238 1 LTVSGANV-----HNLQNLDVSIPLNVLVVVTGVSGSGKSTLV---NEGLY------ASGKARLISF------------- 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 akvgmvfqKPTPFPMSIydnIAFGvrlfeKLSRadmdervqwaLTKAALwneTKDKLHQSGYSLSGGQQQRLCIARGIAI 170
Cdd:cd03238 54 --------LPKFSRNKL---IFID-----QLQF----------LIDVGL---GYLTLGQKLSTLSGGELQRVKLASELFS 104
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 171 RPE--VLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHN---MQQA 215
Cdd:cd03238 105 EPPgtLFILDEPSTGLHQQDINQLLEVIKGLiDLGNTVILIEHNldvLSSA 155
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
33-210 |
6.65e-08 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 52.96 E-value: 6.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 33 IAKNQVTAFIGPSGCGKSTLLRTFnkmfelypEQRAEGEILLDgdNILTNTQDIA--LLRaKVGMVFQKPTPFP-MSIYD 109
Cdd:PLN03211 91 ASPGEILAVLGPSGSGKSTLLNAL--------AGRIQGNNFTG--TILANNRKPTkqILK-RTGFVTQDDILYPhLTVRE 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 110 NIAFG--VRLFEKLSRadmDERVQWALTKAALWNETKDKLHQSGYS----LSGGQQQRLCIARGIAIRPEVLLLDEPCSA 183
Cdd:PLN03211 160 TLVFCslLRLPKSLTK---QEKILVAESVISELGLTKCENTIIGNSfirgISGGERKRVSIAHEMLINPSLLILDEPTSG 236
|
170 180
....*....|....*....|....*...
gi 1897751821 184 LDPISTGR-IEELITELKEDYTVVIVTH 210
Cdd:PLN03211 237 LDATAAYRlVLTLGSLAQKGKTIVTSMH 264
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
23-242 |
8.79e-08 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 51.74 E-value: 8.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 23 FHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKmfELYPeqrAEGEILLDGDniltntqdIALLRAKVGMVFQkptp 102
Cdd:PRK13546 37 FFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGG--SLSP---TVGKVDRNGE--------VSVIAISAGLSGQ---- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 103 fpMSIYDNIAFGVRLF---EKLSRADMDERVQWAltkaalwnETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDE 179
Cdd:PRK13546 100 --LTGIENIEFKMLCMgfkRKEIKAMTPKIIEFS--------ELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDE 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 180 PCSALDPISTGRIEELITELKE-DYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTK 242
Cdd:PRK13546 170 ALSVGDQTFAQKCLDKIYEFKEqNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGELDDVLPK 233
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
1-213 |
9.82e-08 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 52.26 E-value: 9.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 1 MSMVDTA-PGKI--QVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLL--------------RTFNKM---- 59
Cdd:PRK11147 307 MQVEEASrSGKIvfEMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLklmlgqlqadsgriHCGTKLevay 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 60 F-----ELYPEQR-----AEG--EILLDGD--NILTNTQDIaLLRAKVGMvfqkpTPfpmsiydniafgvrlfeklsrad 125
Cdd:PRK11147 387 FdqhraELDPEKTvmdnlAEGkqEVMVNGRprHVLGYLQDF-LFHPKRAM-----TP----------------------- 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 126 mdervqwalTKAalwnetkdklhqsgysLSGGQQQRLCIARgIAIRPEVLL-LDEPCSALDpistgrIE--ELITELKED 202
Cdd:PRK11147 438 ---------VKA----------------LSGGERNRLLLAR-LFLKPSNLLiLDEPTNDLD------VEtlELLEELLDS 485
|
250
....*....|...
gi 1897751821 203 Y--TVVIVTHNMQ 213
Cdd:PRK11147 486 YqgTVLLVSHDRQ 498
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
55-235 |
1.66e-07 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 51.47 E-value: 1.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 55 TFNKMFELYPeQRAEGEILLDGDNILTNT------QDIALL---RAKVGMVFQkptpfpMSIYDNIAFGV-RLFEKLSRA 124
Cdd:PRK13549 304 LVQCLFGAYP-GRWEGEIFIDGKPVKIRNpqqaiaQGIAMVpedRKRDGIVPV------MGVGKNITLAAlDRFTGGSRI 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 125 DMDERVQWAltkaalwNETKDKLH-------QSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELIT 197
Cdd:PRK13549 377 DDAAELKTI-------LESIQRLKvktaspeLAIARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLIN 449
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1897751821 198 EL-KEDYTVVIVTHNMQQAARCSDHTAFMYLGELI-EFSN 235
Cdd:PRK13549 450 QLvQQGVAIIVISSELPEVLGLSDRVLVMHEGKLKgDLIN 489
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
11-210 |
1.69e-07 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 51.43 E-value: 1.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 11 IQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkMFELYPEqraEGEILLdGDNiltntqdiallr 90
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTL--VGELEPD---SGTVKW-SEN------------ 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 91 AKVGMvfqkptpFPMSIYDNIAFGVRLFEKLSR----ADMDERVQWALTKAALwneTKDKLHQSGYSLSGGQQQRLCIAR 166
Cdd:PRK15064 382 ANIGY-------YAQDHAYDFENDLTLFDWMSQwrqeGDDEQAVRGTLGRLLF---SQDDIKKSVKVLSGGEKGRMLFGK 451
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1897751821 167 GIAIRPEVLLLDEPCSALDPIStgrIEELITELkEDY--TVVIVTH 210
Cdd:PRK15064 452 LMMQKPNVLVMDEPTNHMDMES---IESLNMAL-EKYegTLIFVSH 493
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
1-210 |
2.80e-07 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 50.89 E-value: 2.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 1 MSMVD---TAPGKIQVRD---LNFYYGkfhalkninldiAKNQVtafIGPSGCGKSTLLRTfnkMFELypEQRAEGE-IL 73
Cdd:PRK11819 7 YTMNRvskVVPPKKQILKdisLSFFPG------------AKIGV---LGLNGAGKSTLLRI---MAGV--DKEFEGEaRP 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 74 LDGdniltntqdiallrAKVGMVFQKPTPFP-MSIYDNIAFGVR-LFEKLSR------------ADMDE------RVQWA 133
Cdd:PRK11819 67 APG--------------IKVGYLPQEPQLDPeKTVRENVEEGVAeVKAALDRfneiyaayaepdADFDAlaaeqgELQEI 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 134 LTKAALWN-ETK-----DKLH-----QSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELItelkED 202
Cdd:PRK11819 133 IDAADAWDlDSQleiamDALRcppwdAKVTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLEQFL----HD 208
|
250
....*....|
gi 1897751821 203 Y--TVVIVTH 210
Cdd:PRK11819 209 YpgTVVAVTH 218
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
10-210 |
3.22e-07 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 50.74 E-value: 3.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 10 KIQVRDLNFYYGK--FhALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFelypeQRAEGEILLDGDNIltNTQDIA 87
Cdd:PRK10522 322 TLELRNVTFAYQDngF-SVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLY-----QPQSGEILLDGKPV--TAEQPE 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 88 LLRAKVGMVFQKptpfpmsiydniafgVRLFEKLsradMDERVQWALTKAA-LWNET---KDKLHQSGY-----SLSGGQ 158
Cdd:PRK10522 394 DYRKLFSAVFTD---------------FHLFDQL----LGPEGKPANPALVeKWLERlkmAHKLELEDGrisnlKLSKGQ 454
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1897751821 159 QQRLCIARGIAIRPEVLLLDEPCSALDPISTgRI--EELITELKE-DYTVVIVTH 210
Cdd:PRK10522 455 KKRLALLLALAEERDILLLDEWAADQDPHFR-REfyQVLLPLLQEmGKTIFAISH 508
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
149-230 |
7.72e-07 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 49.66 E-value: 7.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 149 QSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVI-VTHNMQQAARCSDHTAFMYL 227
Cdd:PRK15439 399 QAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNVAVLfISSDLEEIEQMADRVLVMHQ 478
|
...
gi 1897751821 228 GEL 230
Cdd:PRK15439 479 GEI 481
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
6-210 |
1.26e-06 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 49.03 E-value: 1.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 6 TAPGKIQVRDLNFYY------GKFHaLKNINLDIAKNQVTAFIGPSGCGKSTLLrtfnKMFE-LYPEQraEGEILLDGDN 78
Cdd:COG4615 323 ADFQTLELRGVTYRYpgedgdEGFT-LGPIDLTIRRGELVFIVGGNGSGKSTLA----KLLTgLYRPE--SGEILLDGQP 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 79 IltNTQDIALLRAKVGMVFqkpTPFpmsiYdniafgvrLFEKL---SRADMDERVQWALTKAALwnetKDKLH-QSGY-- 152
Cdd:COG4615 396 V--TADNREAYRQLFSAVF---SDF----H--------LFDRLlglDGEADPARARELLERLEL----DHKVSvEDGRfs 454
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 153 --SLSGGQQQRLciARGIAI---RPeVLLLDEPCSALDPISTgRI--EELITELKED-YTVVIVTH 210
Cdd:COG4615 455 ttDLSQGQRKRL--ALLVALledRP-ILVFDEWAADQDPEFR-RVfyTELLPELKARgKTVIAISH 516
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
24-221 |
1.84e-06 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 47.61 E-value: 1.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTLLrtfNKMfeLYP--EQRAEGEILLDGdniltNTQDIALLRA--KVGMVFQK 99
Cdd:cd03271 9 NNLKNIDVDIPLGVLTCVTGVSGSGKSSLI---NDT--LYPalARRLHLKKEQPG-----NHDRIEGLEHidKVIVIDQS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 100 P---TP--------------------------------------------FPMSIYDNIAFgvrlFEKLSRadMDERVQw 132
Cdd:cd03271 79 PigrTPrsnpatytgvfdeirelfcevckgkrynretlevrykgksiadvLDMTVEEALEF----FENIPK--IARKLQ- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 133 ALTKAALwnetkD--KLHQSGYSLSGGQQQRLCIARGIAIR---PEVLLLDEPCSALdpiSTGRIEELITELKE----DY 203
Cdd:cd03271 152 TLCDVGL-----GyiKLGQPATTLSGGEAQRIKLAKELSKRstgKTLYILDEPTTGL---HFHDVKKLLEVLQRlvdkGN 223
|
250
....*....|....*...
gi 1897751821 204 TVVIVTHNMqQAARCSDH 221
Cdd:cd03271 224 TVVVIEHNL-DVIKCADW 240
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
29-208 |
2.56e-06 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 47.98 E-value: 2.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 29 INLDIAKNQVTAFIGPSGCGKSTLLRTfnkmfeLY-PEQRAEGEILLDGDNILTNT------QDIALL---RAKVGMVfq 98
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKL------LYgATRRTAGQVYLDGKPIDIRSprdairAGIMLCpedRKAEGII-- 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 99 kptpfPM-SIYDNIA---------FGVRLFEKLSRADMDERVQwaltkaALWNETKDKlHQSGYSLSGGQQQRLCIARGI 168
Cdd:PRK11288 344 -----PVhSVADNINisarrhhlrAGCLINNRWEAENADRFIR------SLNIKTPSR-EQLIMNLSGGNQQKAILGRWL 411
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIV 208
Cdd:PRK11288 412 SEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLF 451
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
24-52 |
3.98e-06 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 47.71 E-value: 3.98e-06
10 20
....*....|....*....|....*....
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTL 52
Cdd:COG0178 14 HNLKNIDVDIPRNKLVVITGLSGSGKSSL 42
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
24-52 |
4.79e-06 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 47.37 E-value: 4.79e-06
10 20
....*....|....*....|....*....
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTL 52
Cdd:PRK00349 14 HNLKNIDLDIPRDKLVVFTGLSGSGKSSL 42
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
5-185 |
6.64e-06 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 46.78 E-value: 6.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 5 DTAPGK--IQVRDLNF-YYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRtfnkmfelypeqraegeiLLDGDniLT 81
Cdd:PLN03073 501 DDRPGPpiISFSDASFgYPGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILK------------------LISGE--LQ 560
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 82 NTQDIALLRAKVGM-VFQK-----------PTPFPMSIYDNIAfgvrlfEKLSRADMDErvqwaltkaalWNETKDKLHQ 149
Cdd:PLN03073 561 PSSGTVFRSAKVRMaVFSQhhvdgldlssnPLLYMMRCFPGVP------EQKLRAHLGS-----------FGVTGNLALQ 623
|
170 180 190
....*....|....*....|....*....|....*.
gi 1897751821 150 SGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALD 185
Cdd:PLN03073 624 PMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD 659
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
24-71 |
1.17e-05 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 46.16 E-value: 1.17e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTLlrTFNKMFelypeqrAEGE 71
Cdd:TIGR00630 10 HNLKNIDVEIPRDKLVVITGLSGSGKSSL--AFDTIY-------AEGQ 48
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
42-210 |
1.31e-05 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 45.90 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 42 IGPSGCGKSTLLRTFNkmfELYPeqraegeiLLDGdnILTNTQDIALLrakvgMVFQKP----------TPFPMSIYDNI 111
Cdd:TIGR00954 484 CGPNGCGKSSLFRILG---ELWP--------VYGG--RLTKPAKGKLF-----YVPQRPymtlgtlrdqIIYPDSSEDMK 545
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 112 AFGVR---LFEKLSRADMDErvqwALTKAALWNETKDKLHQsgysLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPIS 188
Cdd:TIGR00954 546 RRGLSdkdLEQILDNVQLTH----ILEREGGWSAVQDWMDV----LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDV 617
|
170 180
....*....|....*....|..
gi 1897751821 189 TGRIEELITELKedYTVVIVTH 210
Cdd:TIGR00954 618 EGYMYRLCREFG--ITLFSVSH 637
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
12-241 |
1.38e-05 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 45.65 E-value: 1.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 12 QVRDLNFYYGK--FH-ALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDniltntqdIAL 88
Cdd:PRK13545 23 KLKDLFFRSKDgeYHyALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGV-----TMPNKGTVDIKGS--------AAL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 89 LRAKVGMVFQkptpfpMSIYDNIAFgvrlfEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGI 168
Cdd:PRK13545 90 IAISSGLNGQ------LTGIENIEL-----KGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISV 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 169 AIRPEVLLLDEPCSALDPISTGRIEELITELKED-YTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFT 241
Cdd:PRK13545 159 HINPDILVIDEALSVGDQTFTKKCLDKMNEFKEQgKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVD 232
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
154-212 |
1.68e-05 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 45.57 E-value: 1.68e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1897751821 154 LSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNM 212
Cdd:PRK13409 213 LSGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQRLNVARLIRELAEGKYVLVVEHDL 271
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
35-235 |
5.96e-05 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 41.98 E-value: 5.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 35 KNQVTAFIGPSGCGKSTLLRTFNKMFelypEQRAEGEILLDGDNILTNTQDIALLrakvgmvfqkptpfpmsiydniafg 114
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALAREL----GPPGGGVIYIDGEDILEEVLDQLLL------------------------- 51
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 115 vrlfeklsradmdervqwaltkaalwnetkDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEE 194
Cdd:smart00382 52 ------------------------------IIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLL 101
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1897751821 195 LIT------ELKEDYTVVIVTHNMQQAARcsDHTAFMYLGELIEFSN 235
Cdd:smart00382 102 LEElrllllLKSEKNLTVILTTNDEKDLG--PALLRRRFDRRIVLLL 146
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
143-210 |
6.22e-05 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 44.08 E-value: 6.22e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 143 TKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELIteLKEDYTVVIVTH 210
Cdd:PLN03073 334 TPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYL--LKWPKTFIVVSH 399
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
38-210 |
7.03e-05 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 42.59 E-value: 7.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 38 VTAFIGPSGCGKSTLLRTFNkmFELYPEQRAeGEILLDGDNILTNTQDIallRAKVGMVFQKPTPFPM------SIYDNI 111
Cdd:cd03240 24 LTLIVGQNGAGKTTIIEALK--YALTGELPP-NSKGGAHDPKLIREGEV---RAQVKLAFENANGKKYtitrslAILENV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 112 AFgVRlfeklsradmDERVQWALTkaalwnETKDklhqsgySLSGGQQQ------RLCIARGIAIRPEVLLLDEPCSALD 185
Cdd:cd03240 98 IF-CH----------QGESNWPLL------DMRG-------RCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLD 153
|
170 180
....*....|....*....|....*...
gi 1897751821 186 PIS-TGRIEELITELKEDYT--VVIVTH 210
Cdd:cd03240 154 EENiEESLAEIIEERKSQKNfqLIVITH 181
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
26-185 |
1.03e-04 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 43.23 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFnkmfelypeqraEGEILLDGDNIlTNTQDIALlrakvGMVFQKPTPFPM 105
Cdd:PRK10636 17 LDNATATINPGQKVGLVGKNGCGKSTLLALL------------KNEISADGGSY-TFPGNWQL-----AWVNQETPALPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 106 SIYDNIAFGVRLFEKLSRA------------------DMDERVQWALTK--AALWNE---TKDKLHQSGYSLSGGQQQRL 162
Cdd:PRK10636 79 PALEYVIDGDREYRQLEAQlhdanerndghaiatihgKLDAIDAWTIRSraASLLHGlgfSNEQLERPVSDFSGGWRMRL 158
|
170 180
....*....|....*....|...
gi 1897751821 163 CIARGIAIRPEVLLLDEPCSALD 185
Cdd:PRK10636 159 NLAQALICRSDLLLLDEPTNHLD 181
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
147-225 |
1.30e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 42.89 E-value: 1.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 147 LHQSGYSLSGGQQQRLCIARGIAIRPE--VLLLDEPCSALDPISTGRIEELITELKEDYTVVIVTHNMQQAARCSDHTAF 224
Cdd:PRK00635 1381 LGQEQDTLSDGEHYRLHLAKKISSNLTdiIYLLEDPLSGLHPQDAPTLLQLIKELVTNNNTVIATDRSGSLAEHADHLIH 1460
|
.
gi 1897751821 225 M 225
Cdd:PRK00635 1461 L 1461
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
152-221 |
1.74e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 42.51 E-value: 1.74e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 152 YSLSGGQQQRLCIARGI---AIRPEVLLLDEPCSALdpiSTGRIEELITELK----EDYTVVIVTHNMqQAARCSDH 221
Cdd:PRK00635 808 SSLSGGEIQRLKLAYELlapSKKPTLYVLDEPTTGL---HTHDIKALIYVLQslthQGHTVVIIEHNM-HVVKVADY 880
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
154-226 |
1.77e-04 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 40.81 E-value: 1.77e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1897751821 154 LSGGQQQR--LCIARGIA-IRPEVL-LLDEPCSALDPISTGRIEELITE-LKEDYTVVIVTHNMQQAARcSDHTAFMY 226
Cdd:cd03227 78 LSGGEKELsaLALILALAsLKPRPLyILDEIDRGLDPRDGQALAEAILEhLVKGAQVIVITHLPELAEL-ADKLIHIK 154
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
37-226 |
2.35e-04 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 41.58 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 37 QVTAFIGPSGCGKSTLLRTFNKmfELYPE-QRAEGEIllDGDNILTNTQDIAL------LRAKVGMVFQKPtpfpmSIYD 109
Cdd:cd03236 27 QVLGLVGPNGIGKSTALKILAG--KLKPNlGKFDDPP--DWDEILDEFRGSELqnyftkLLEGDVKVIVKP-----QYVD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 110 NI--AFGVRLFEKLSRADmdERVQWALTKAALwnETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPI 187
Cdd:cd03236 98 LIpkAVKGKVGELLKKKD--ERGKLDELVDQL--ELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIK 173
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1897751821 188 STGRIEELITEL-KEDYTVVIVTHNMQQAARCSDHTAFMY 226
Cdd:cd03236 174 QRLNAARLIRELaEDDNYVLVVEHDLAVLDYLSDYIHCLY 213
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
153-212 |
2.44e-04 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 42.08 E-value: 2.44e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1897751821 153 SLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITEL-KEDYTVVIVTHNM 212
Cdd:COG1245 212 ELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIYQRLNVARLIRELaEEGKYVLVVEHDL 272
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
153-228 |
2.75e-04 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 41.92 E-value: 2.75e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1897751821 153 SLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITE-LKEDYTVVIVTHNMQQAARCSDHTAFMYLG 228
Cdd:TIGR01257 2070 TYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSiIREGRAVVLTSHSMEECEALCTRLAIMVKG 2146
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
26-179 |
3.86e-04 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 40.24 E-value: 3.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1897751821 26 LKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMfelypEQRAEGEILLDGDNIlTNTQD--IALLRAKVGMVFQkptpf 103
Cdd:PRK13541 16 LFDLSITFLPSAITYIKGANGCGKSSLLRMIAGI-----MQPSSGNIYYKNCNI-NNIAKpyCTYIGHNLGLKLE----- 84
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1897751821 104 pMSIYDNIAFGVRLFeklsraDMDERVQWALTKAALwnetKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDE 179
Cdd:PRK13541 85 -MTVFENLKFWSEIY------NSAETLYAAIHYFKL----HDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDE 149
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
146-212 |
4.29e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 41.54 E-value: 4.29e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 146 KLHQSGYSLSGGQQQRLCIARGIAIR---PEVLLLDEPCSALdpiSTGRIEELITEL----KEDYTVVIVTHNM 212
Cdd:TIGR00630 822 RLGQPATTLSGGEAQRIKLAKELSKRstgRTLYILDEPTTGL---HFDDIKKLLEVLqrlvDKGNTVVVIEHNL 892
|
|
| PRK00098 |
PRK00098 |
GTPase RsgA; Reviewed |
35-72 |
4.79e-04 |
|
GTPase RsgA; Reviewed
Pssm-ID: 234631 [Multi-domain] Cd Length: 298 Bit Score: 40.57 E-value: 4.79e-04
10 20 30
....*....|....*....|....*....|....*....
gi 1897751821 35 KNQVTAFIGPSGCGKSTLLrtfNKmfeLYPEQRAE-GEI 72
Cdd:PRK00098 163 AGKVTVLAGQSGVGKSTLL---NA---LAPDLELKtGEI 195
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
24-53 |
6.08e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 40.77 E-value: 6.08e-04
10 20 30
....*....|....*....|....*....|
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTLL 53
Cdd:TIGR00630 622 NNLKNITVSIPLGLFTCITGVSGSGKSTLI 651
|
|
| AAA_15 |
pfam13175 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
23-60 |
6.78e-04 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433011 [Multi-domain] Cd Length: 392 Bit Score: 40.27 E-value: 6.78e-04
10 20 30
....*....|....*....|....*....|....*...
gi 1897751821 23 FHALKNINLDIaKNQVTAFIGPSGCGKSTLLRTFNKMF 60
Cdd:pfam13175 11 FRCLKDTEIDL-DEDLTVLIGKNNSGKSSILEALDIFL 47
|
|
| RsgA_GTPase |
pfam03193 |
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are ... |
35-72 |
2.02e-03 |
|
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are broadly conserved in bacteria and are indispensable for growth. The GTPase domain of RsgA is very similar to several P-loop GTPases, but differs in having a circular permutation of the GTPase structure described by a G4-G1-G3 pattern.
Pssm-ID: 427191 [Multi-domain] Cd Length: 174 Bit Score: 37.91 E-value: 2.02e-03
10 20 30
....*....|....*....|....*....|....*....
gi 1897751821 35 KNQVTAFIGPSGCGKSTLLRTfnkmfeLYPEQRAE-GEI 72
Cdd:pfam03193 105 KGKTTVLAGQSGVGKSTLLNA------LLPELDLRtGEI 137
|
|
| YjeQ_EngC |
cd01854 |
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ... |
35-72 |
2.17e-03 |
|
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.
Pssm-ID: 206747 [Multi-domain] Cd Length: 211 Bit Score: 38.15 E-value: 2.17e-03
10 20 30
....*....|....*....|....*....|....*....
gi 1897751821 35 KNQVTAFIGPSGCGKSTLLRTfnkmfeLYPEQRAE-GEI 72
Cdd:cd01854 84 KGKTSVLVGQSGVGKSTLLNA------LLPELVLAtGEI 116
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
23-56 |
2.59e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 38.76 E-value: 2.59e-03
10 20 30
....*....|....*....|....*....|....
gi 1897751821 23 FHALKNINLDIAknQVTAFIGPSGCGKSTLLRTF 56
Cdd:COG4637 10 FKSLRDLELPLG--PLTVLIGANGSGKSNLLDAL 41
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
153-180 |
3.51e-03 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 38.23 E-value: 3.51e-03
10 20
....*....|....*....|....*...
gi 1897751821 153 SLSGGQQQRLCIARGIAIRPEVLLLDEP 180
Cdd:NF040905 404 NLSGGNQQKVVLSKWLFTDPDVLILDEP 431
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
152-211 |
3.81e-03 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 38.14 E-value: 3.81e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1897751821 152 YSLSGGQQQRLCIA---RGIAIRPEVLLLDEPCSALDPISTGRIEELITELKEDYT-VVIVTHN 211
Cdd:pfam13304 235 FELSDGTKRLLALLaalLSALPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAqLILTTHS 298
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
24-52 |
7.46e-03 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 37.31 E-value: 7.46e-03
10 20
....*....|....*....|....*....
gi 1897751821 24 HALKNINLDIAKNQVTAFIGPSGCGKSTL 52
Cdd:COG0178 619 NNLKNVDVEIPLGVLTCVTGVSGSGKSTL 647
|
|
| |
