|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05218 |
PRK05218 |
heat shock protein 90; Provisional |
4-623 |
0e+00 |
|
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain] Cd Length: 613 Bit Score: 1127.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGV 83
Cdd:PRK05218 3 METGEFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAIDKLRFEALTDPALYEGDGDLKIRISFDKEARTLTISDNGI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 84 GMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKpENGVFWESAGEGEYT 163
Cdd:PRK05218 83 GMTREEVIENLGTIAKSGTKEFLEKLKGDQKKDSQLIGQFGVGFYSAFMVADKVTVITRSAGPA-AEAVRWESDGEGEYT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 164 VADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREekdgetvisWEKINKAQALWTRNKSEITD 243
Cdd:PRK05218 162 IEEIEKEERGTEITLHLKEDEDEFLDEWRIRSIIKKYSDFIPVPIKLEKEE---------EETINSASALWTRSKSEITD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 244 EEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRG 323
Cdd:PRK05218 233 EEYKEFYKHLAHDFDDPLFWIHNNVEGPFEYTGLLYIPKKAPFDLFNRDRKGGLKLYVKRVFIMDDAEELLPEYLRFVKG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 324 LIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFA 403
Cdd:PRK05218 313 VIDSEDLPLNVSREILQEDRVVKKIRKAITKKVLDELEKLAKNDREKYEKFWKEFGPVLKEGLYEDFANREKLAKLLRFA 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 404 STHtdsSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSV 483
Cdd:PRK05218 393 STH---EGKYVSLAEYVERMKEGQKKIYYITGDSREAAKNSPHLELFKKKGIEVLLLTDPIDEFWISYLEEFDGKPFKSV 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 484 SKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPE 563
Cdd:PRK05218 470 ARGDLDLGKEDEEEKEEKEEAEEEFKPLLERLKEALGDKVKDVRLSHRLTDSPACLVADEGDMSTQMEKLLKAAGQEVPE 549
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 564 VKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLV 623
Cdd:PRK05218 550 SKPILEINPNHPLVKKLADEADEAKFKDLAELLYDQALLAEGGSLEDPAAFVKRLNELLL 609
|
|
| HtpG |
COG0326 |
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ... |
4-623 |
0e+00 |
|
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain] Cd Length: 616 Bit Score: 1061.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGV 83
Cdd:COG0326 3 KETGEFQAEVKQLLDLMIHSLYSNKEIFLRELISNASDAIDKLRFLALTDPELKEEDGDLKIRIEVDKEAKTLTISDNGI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 84 GMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPEnGVFWESAGEGEYT 163
Cdd:COG0326 83 GMTREEVIENLGTIAKSGTREFLEKLKGDQKKDSDLIGQFGVGFYSAFMVADKVEVVTRSAGEDAE-AVRWESDGDGEYT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 164 VADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGEtvisWEKINKAQALWTRNKSEITD 243
Cdd:COG0326 162 IEEAEKAERGTEITLHLKEDAEEFLEEWRLREIIKKYSDFIPVPIKMEGEEEETEE----DETINSATALWTRSKSEITD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 244 EEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRG 323
Cdd:COG0326 238 EEYKEFYKHLFHDFEDPLFWIHLNVEGPFEYTGLLYIPKKAPFDLYDRDRKGGIKLYVKRVFIMDDAEDLLPEYLRFVRG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 324 LIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFA 403
Cdd:COG0326 318 VVDSPDLPLNVSREILQEDRQLKKIRKAITKKVLDELEKLAKNDREKYEKFWKEFGLVLKEGALEDFKNREKIADLLRFE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 404 STHTDssaQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSV 483
Cdd:COG0326 398 STKEG---GYVTLAEYVERMKEGQKKIYYITGESREAAEQSPHLEIFKAKGIEVLLLTDPIDEFLISHLEEFDGKKFKSV 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 484 SKVDESLEKLADEvdESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPE 563
Cdd:COG0326 475 DSGDLDLDKLEEK--KESEEEEEEFKPLLERFKEALGDKVKDVRVSARLTDSPACLVADEGDMSRRMEKMLKAMGQDMPE 552
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 564 VKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLV 623
Cdd:COG0326 553 AKPILEINPNHPLVKKLAAEEDEELFKDLAELLYDQALLAEGGLLEDPAAFVKRLNKLLE 612
|
|
| HSP90 |
pfam00183 |
Hsp90 protein; |
186-622 |
4.73e-144 |
|
Hsp90 protein;
Pssm-ID: 459703 Cd Length: 516 Bit Score: 427.74 E-value: 4.73e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 186 EFLDDWRVRSIISKYSDHIALP----------VEIEKREEKDG-----------------------------ETVISWEK 226
Cdd:pfam00183 1 EYLEEKKIKELVKKYSEFINFPiylwvekeeeVEVPDEEEEEEeeeeeeedddpkveeedeeeekkktkkvkETVWEWEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 227 INKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKH-GLKLYVQRVF 305
Cdd:pfam00183 81 LNKTKPIWTRNPKEVTEEEYAEFYKSLSKDWEDPLAVKHFSVEGEVEFKSLLFIPKRAPFDLFENKKKKnNIKLYVRRVF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 306 IMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDaEKYQTFWQQFGLVLKEG 385
Cdd:pfam00183 161 ITDDFEDLIPEYLNFVKGVVDSDDLPLNVSRETLQQNKILKVIKKKLVRKALDMFKEIAEEK-EDYKKFWKEFGKNLKLG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 386 PAEDFANQEAIAKLLRFASTHtdSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRID 465
Cdd:pfam00183 240 IIEDSSNRNKLAKLLRFYSSK--SGDELTSLDDYVSRMKEGQKHIYYITGESKEEVENSPFLERLKKKGYEVLYLTDPID 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 466 EWMMNYLTEFDGKPFQSVSKVDESLEKLADEvDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADE 545
Cdd:pfam00183 318 EYAVQQLKEFDGKKLVNVAKEGLELEEDEEE-KKKDEELKKEFEPLTKWLKDVLGDKVEKVVVSNRLVDSPCVLVTSQYG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 546 MSTQMAKLFAA-AGQKVP------EVKYIFELNPDHVLVK----RAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLF 614
Cdd:pfam00183 397 WSANMERIMKAqALRKDSsmssymSSKKTLEINPRHPIIKellkRVEADKDDKTAKDLALLLYETALLRSGFSLEDPASF 476
|
....*...
gi 1929623672 615 IRRMNQLL 622
Cdd:pfam00183 477 ASRIYRML 484
|
|
| HATPase_Hsp90-like |
cd16927 |
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ... |
14-204 |
1.52e-107 |
|
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain] Cd Length: 189 Bit Score: 321.78 E-value: 1.52e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 14 KQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDH 93
Cdd:cd16927 1 NQLLDLIIHSLYSNKEIFLRELISNASDALDKLRYLSLTDPSLLDDDPELEIRISPDKENRTLTISDTGIGMTKEELINN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 94 LGTIAKSGTKSFLESLGSDqAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEkpENGVFWESAGEGEYTVADITKE-DR 172
Cdd:cd16927 81 LGTIARSGTKAFLEALQEG-AKDSDLIGQFGVGFYSAFMVADKVTVTTKSAGD--DEGYRWESDGGGSYTIEEAEGElGR 157
|
170 180 190
....*....|....*....|....*....|..
gi 1929623672 173 GTEITLHLREGEDEFLDDWRVRSIISKYSDHI 204
Cdd:cd16927 158 GTKITLHLKEDAKEFLEEARIKELVKKYSDFI 189
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
27-154 |
8.07e-13 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 64.98 E-value: 8.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 27 NKEIFLRELISNASDAADKLRFRalsnpdlyegDGELRVRVSFDKDKRTLTISDNGVGMTrDEVIDHLgtiaksgtksFL 106
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPE----------GGRITVTLERDGDHVEITVEDNGPGIP-PEDLEKI----------FE 59
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1929623672 107 ESLGSDqaKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFW 154
Cdd:smart00387 60 PFFRTD--KRSRKIGGTGLGLSIVKKLVELHGGEISVESEPGGGTTFT 105
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05218 |
PRK05218 |
heat shock protein 90; Provisional |
4-623 |
0e+00 |
|
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain] Cd Length: 613 Bit Score: 1127.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGV 83
Cdd:PRK05218 3 METGEFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAIDKLRFEALTDPALYEGDGDLKIRISFDKEARTLTISDNGI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 84 GMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKpENGVFWESAGEGEYT 163
Cdd:PRK05218 83 GMTREEVIENLGTIAKSGTKEFLEKLKGDQKKDSQLIGQFGVGFYSAFMVADKVTVITRSAGPA-AEAVRWESDGEGEYT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 164 VADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREekdgetvisWEKINKAQALWTRNKSEITD 243
Cdd:PRK05218 162 IEEIEKEERGTEITLHLKEDEDEFLDEWRIRSIIKKYSDFIPVPIKLEKEE---------EETINSASALWTRSKSEITD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 244 EEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRG 323
Cdd:PRK05218 233 EEYKEFYKHLAHDFDDPLFWIHNNVEGPFEYTGLLYIPKKAPFDLFNRDRKGGLKLYVKRVFIMDDAEELLPEYLRFVKG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 324 LIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFA 403
Cdd:PRK05218 313 VIDSEDLPLNVSREILQEDRVVKKIRKAITKKVLDELEKLAKNDREKYEKFWKEFGPVLKEGLYEDFANREKLAKLLRFA 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 404 STHtdsSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSV 483
Cdd:PRK05218 393 STH---EGKYVSLAEYVERMKEGQKKIYYITGDSREAAKNSPHLELFKKKGIEVLLLTDPIDEFWISYLEEFDGKPFKSV 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 484 SKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPE 563
Cdd:PRK05218 470 ARGDLDLGKEDEEEKEEKEEAEEEFKPLLERLKEALGDKVKDVRLSHRLTDSPACLVADEGDMSTQMEKLLKAAGQEVPE 549
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 564 VKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLV 623
Cdd:PRK05218 550 SKPILEINPNHPLVKKLADEADEAKFKDLAELLYDQALLAEGGSLEDPAAFVKRLNELLL 609
|
|
| HtpG |
COG0326 |
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ... |
4-623 |
0e+00 |
|
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain] Cd Length: 616 Bit Score: 1061.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 4 QETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGV 83
Cdd:COG0326 3 KETGEFQAEVKQLLDLMIHSLYSNKEIFLRELISNASDAIDKLRFLALTDPELKEEDGDLKIRIEVDKEAKTLTISDNGI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 84 GMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPEnGVFWESAGEGEYT 163
Cdd:COG0326 83 GMTREEVIENLGTIAKSGTREFLEKLKGDQKKDSDLIGQFGVGFYSAFMVADKVEVVTRSAGEDAE-AVRWESDGDGEYT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 164 VADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGEtvisWEKINKAQALWTRNKSEITD 243
Cdd:COG0326 162 IEEAEKAERGTEITLHLKEDAEEFLEEWRLREIIKKYSDFIPVPIKMEGEEEETEE----DETINSATALWTRSKSEITD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 244 EEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRG 323
Cdd:COG0326 238 EEYKEFYKHLFHDFEDPLFWIHLNVEGPFEYTGLLYIPKKAPFDLYDRDRKGGIKLYVKRVFIMDDAEDLLPEYLRFVRG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 324 LIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFA 403
Cdd:COG0326 318 VVDSPDLPLNVSREILQEDRQLKKIRKAITKKVLDELEKLAKNDREKYEKFWKEFGLVLKEGALEDFKNREKIADLLRFE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 404 STHTDssaQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSV 483
Cdd:COG0326 398 STKEG---GYVTLAEYVERMKEGQKKIYYITGESREAAEQSPHLEIFKAKGIEVLLLTDPIDEFLISHLEEFDGKKFKSV 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 484 SKVDESLEKLADEvdESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPE 563
Cdd:COG0326 475 DSGDLDLDKLEEK--KESEEEEEEFKPLLERFKEALGDKVKDVRVSARLTDSPACLVADEGDMSRRMEKMLKAMGQDMPE 552
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 564 VKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLV 623
Cdd:COG0326 553 AKPILEINPNHPLVKKLAAEEDEELFKDLAELLYDQALLAEGGLLEDPAAFVKRLNKLLE 612
|
|
| PTZ00272 |
PTZ00272 |
heat shock protein 83 kDa (Hsp83); Provisional |
5-622 |
6.13e-168 |
|
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341 Cd Length: 701 Bit Score: 495.74 E-value: 6.13e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 5 ETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVG 84
Cdd:PTZ00272 3 ETFAFQAEINQLMSLIINTFYSNKEIFLRELISNASDACDKIRYQSLTDPSVLGESPRLCIRVVPDKENKTLTVEDNGIG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 85 MTRDEVIDHLGTIAKSGTKSFLESLgsDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPengVFWESAGEGEYTV 164
Cdd:PTZ00272 83 MTKADLVNNLGTIARSGTKAFMEAL--EAGGDMSMIGQFGVGFYSAYLVADRVTVTSKNNSDES---YVWESSAGGTFTI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 165 ADITKED--RGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVE--IEKREEKD----------------------- 217
Cdd:PTZ00272 158 TSTPESDmkRGTRITLHLKEDQMEYLEPRRLKELIKKHSEFIGYDIElmVEKTTEKEvtdedeedtkkadedgeepkvee 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 218 ---------------GETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPS 282
Cdd:PTZ00272 238 vkegdegkkkktkkvKEVTKEYEVQNKHKPLWTRDPKDVTKEEYAAFYKAISNDWEDPAATKHFSVEGQLEFRSIMFVPK 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 283 QAPWDMWNRDHK-HGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLE 361
Cdd:PTZ00272 318 RAPFDMFEPNKKrNNIKLYVRRVFIMDNCEDLCPDWLGFVKGVVDSEDLPLNISRENLQQNKILKVIRKNIVKKCLEMFD 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 362 KLAkDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFASthTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAA 441
Cdd:PTZ00272 398 EVA-ENKEDYKQFYEQFGKNIKLGIHEDTANRKKLMELLRFYS--TESGEEMTTLKDYVTRMKAGQKSIYYITGDSKKKL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 442 KSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKlADEVDESAKEAEKALTPFIDRVKALLGE 521
Cdd:PTZ00272 475 ETSPFIEQARRRGLEVLFMTEPIDEYVMQQVKDFEDKKFACLTKEGVHFEE-SEEEKQQREEEKAACEKLCKTMKEVLGD 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 522 RVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEV------KYIFELNPDHVLVK----RAADTEDEAKFSE 591
Cdd:PTZ00272 554 KVEKVIVSERLSTSPCILVTSEFGWSAHMEQIMRNQALRDSSMaqymmsKKTMELNPRHPIIKelrrRVGADENDKAVKD 633
|
650 660 670
....*....|....*....|....*....|.
gi 1929623672 592 WVELLLDQALLAERGTLEDPNLFIRRMNQLL 622
Cdd:PTZ00272 634 LVFLLFDTSLLTSGFQLEDPTGYAERINRMI 664
|
|
| HSP90 |
pfam00183 |
Hsp90 protein; |
186-622 |
4.73e-144 |
|
Hsp90 protein;
Pssm-ID: 459703 Cd Length: 516 Bit Score: 427.74 E-value: 4.73e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 186 EFLDDWRVRSIISKYSDHIALP----------VEIEKREEKDG-----------------------------ETVISWEK 226
Cdd:pfam00183 1 EYLEEKKIKELVKKYSEFINFPiylwvekeeeVEVPDEEEEEEeeeeeeedddpkveeedeeeekkktkkvkETVWEWEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 227 INKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKH-GLKLYVQRVF 305
Cdd:pfam00183 81 LNKTKPIWTRNPKEVTEEEYAEFYKSLSKDWEDPLAVKHFSVEGEVEFKSLLFIPKRAPFDLFENKKKKnNIKLYVRRVF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 306 IMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDaEKYQTFWQQFGLVLKEG 385
Cdd:pfam00183 161 ITDDFEDLIPEYLNFVKGVVDSDDLPLNVSRETLQQNKILKVIKKKLVRKALDMFKEIAEEK-EDYKKFWKEFGKNLKLG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 386 PAEDFANQEAIAKLLRFASTHtdSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRID 465
Cdd:pfam00183 240 IIEDSSNRNKLAKLLRFYSSK--SGDELTSLDDYVSRMKEGQKHIYYITGESKEEVENSPFLERLKKKGYEVLYLTDPID 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 466 EWMMNYLTEFDGKPFQSVSKVDESLEKLADEvDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADE 545
Cdd:pfam00183 318 EYAVQQLKEFDGKKLVNVAKEGLELEEDEEE-KKKDEELKKEFEPLTKWLKDVLGDKVEKVVVSNRLVDSPCVLVTSQYG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 546 MSTQMAKLFAA-AGQKVP------EVKYIFELNPDHVLVK----RAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLF 614
Cdd:pfam00183 397 WSANMERIMKAqALRKDSsmssymSSKKTLEINPRHPIIKellkRVEADKDDKTAKDLALLLYETALLRSGFSLEDPASF 476
|
....*...
gi 1929623672 615 IRRMNQLL 622
Cdd:pfam00183 477 ASRIYRML 484
|
|
| PTZ00130 |
PTZ00130 |
heat shock protein 90; Provisional |
2-610 |
3.61e-124 |
|
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain] Cd Length: 814 Bit Score: 386.32 E-value: 3.61e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 2 KGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDN 81
Cdd:PTZ00130 63 SGIEQHQYQTEVTRLMDIIVNSLYTQKEVFLRELISNAADALEKIRFLSLSDESVLGEEKKLEIRISANKEKNILSITDT 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 82 GVGMTRDEVIDHLGTIAKSGTKSFLESLgSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRaagEKPENGVFWESAGEGE 161
Cdd:PTZ00130 143 GIGMTKEDLINNLGTIAKSGTSNFLEAI-SKSGGDMSLIGQFGVGFYSAFLVADKVIVYTK---NNNDEQYIWESTADAK 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 162 YTVADITKE---DRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALP-----------------------------VE 209
Cdd:PTZ00130 219 FTIYKDPRGstlKRGTRISLHLKEDATNLMNDKKLVDLISKYSQFIQYPiyllhenvyteevladiakemendpnydsVK 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 210 IEKREEKDGET------VISWEKINKAQALWTRNKSEITDEEYKEFYKhIAHDFND-PLTWSHNRVEGKQEYTSLLYIPS 282
Cdd:PTZ00130 299 VEETDDPNKKTrtvekkVKKWKLMNEQKPIWLRPPKELTDEDYKKFFS-VLSGFNDePLYHIHFFAEGEIEFKCLIYIPS 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 283 QAPWdmwNRDH----KHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQ 358
Cdd:PTZ00130 378 RAPS---INDHlftkQNSIKLYVRRVLVADEFVEFLPRYMSFVKGVVDSDDLPLNVSREQLQQNKILKAVSKRIVRKILD 454
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 359 MLEKLAKD----------------DAEK-------------YQTFWQQFGLVLKEGPAEDFANQEAIAKLLRFastHTDS 409
Cdd:PTZ00130 455 TFRTLYKEgkknketlraelaketDEEKkkeiqkkinepstYKLIYKEYRKYLKTGCYEDDINRNKIVKLLLF---KTML 531
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 410 SAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDES 489
Cdd:PTZ00130 532 HPKSISLDTYIENMKPDQKFIYYASGDSYEYLSKIPQLQIFKKKNIDVVFLTESVDESCVQRVQEYDGKKFKSIQKGEIT 611
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 490 LEkLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTP-AIVSTDADeMSTQMAKLF-----------AAA 557
Cdd:PTZ00130 612 FE-LTEDEKKKEEKVKKMYKALIDVISDTLRNQIFKVEISRRLVDAPcAVVSTEWG-LSGQMEKLMkinvnnsdqikAMS 689
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1929623672 558 GQKvpevkyIFELNPDHV----LVKRAADTEDEAKFSEWVELLLDQALLAERGTLED 610
Cdd:PTZ00130 690 GQK------ILEINPDHPimidLLKRSVSNPKDSQLTESIKIIYQSAKLASGFDLED 740
|
|
| HATPase_Hsp90-like |
cd16927 |
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ... |
14-204 |
1.52e-107 |
|
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain] Cd Length: 189 Bit Score: 321.78 E-value: 1.52e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 14 KQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDH 93
Cdd:cd16927 1 NQLLDLIIHSLYSNKEIFLRELISNASDALDKLRYLSLTDPSLLDDDPELEIRISPDKENRTLTISDTGIGMTKEELINN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 94 LGTIAKSGTKSFLESLGSDqAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEkpENGVFWESAGEGEYTVADITKE-DR 172
Cdd:cd16927 81 LGTIARSGTKAFLEALQEG-AKDSDLIGQFGVGFYSAFMVADKVTVTTKSAGD--DEGYRWESDGGGSYTIEEAEGElGR 157
|
170 180 190
....*....|....*....|....*....|..
gi 1929623672 173 GTEITLHLREGEDEFLDDWRVRSIISKYSDHI 204
Cdd:cd16927 158 GTKITLHLKEDAKEFLEEARIKELVKKYSDFI 189
|
|
| PRK14083 |
PRK14083 |
HSP90 family protein; Provisional |
7-602 |
6.81e-50 |
|
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain] Cd Length: 601 Bit Score: 182.83 E-value: 6.81e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 7 RGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAadkLRFRALSNPDLyegdgELRVRVS-FDKDKRTLTISDNGVGM 85
Cdd:PRK14083 3 HRFQVDLRGVIDLLSRHLYSSPRVYVRELLQNAVDA---ITARRALDPTA-----PGRIRIElTDAGGGTLIVEDNGIGL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 86 TRDEVIDHLGTIAKSgtkSFLESLGSDQAKDsqLIGQFGVGFYSAFIVADKVTVRTRAAGEKPenGVFWESAGEGEYTVA 165
Cdd:PRK14083 75 TEEEVHEFLATIGRS---SKRDENLGFARND--FLGQFGIGLLSCFLVADEIVVVSRSAKDGP--AVEWRGKADGTYSVR 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 166 DITKEDR--GTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWekiNKAQALWTRNKSEI-- 241
Cdd:PRK14083 148 KLETERAepGTTVYLRPRPDAEEWLERETVEELAKKYGSLLPVPIRVEGEKGGVNETPPPW---TRDYPDPETRREALla 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 242 --TDEEYKEFYKHIahdfndPLTWSHNRVEGkqeytsLLYI-PSQAPWdmwNRDHKHglKLYVQRVFIMDDAEQFMPNYL 318
Cdd:PRK14083 225 ygEELLGFTPLDVI------PLDVPSGGLEG------VAYVlPYAVSP---AARRKH--RVYLKRMLLSEEAENLLPDWA 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 319 RFVRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAK 398
Cdd:PRK14083 288 FFVRCVVNTDELRPTASREALYEDDALAAVREELGEAIRKWLIGLATTDPERLRRLLAVHHLGVKALASHDDELLRLILP 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 399 LLRFasthtDSSAQTVSLEDYVSRMKEgqekIYYI-TADSY------AAAKSSP--------HLELLRKkgievllLSDR 463
Cdd:PRK14083 368 WLPF-----ETTDGRMTLAEIRRRHGV----IRYTsSVDEFrqlapiARAQGMGvinggytyDSELLER-------LPRL 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 464 IDEWmmnyltefdgkpfqSVSKVDesLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRL-TDTPAIVSTD 542
Cdd:PRK14083 432 RPGL--------------TVERLD--PAELTDRLEPLTPEEELALRPFLAEAREVLAPFGCDVVIRHFEpADLPALYLHD 495
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1929623672 543 ADEMSTQMAK--------LFAA-----AGQKVPEVKYIFeLNPDHVLVKRAADTEDEAKFSEWVELLLDQALL 602
Cdd:PRK14083 496 RAAQHSREREeaveeaddLWADilgslDESQPAPRARLV-LNLRNPLVRRLATLGDPKLLSRAVEALYVQALL 567
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
27-154 |
8.07e-13 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 64.98 E-value: 8.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 27 NKEIFLRELISNASDAADKLRFRalsnpdlyegDGELRVRVSFDKDKRTLTISDNGVGMTrDEVIDHLgtiaksgtksFL 106
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPE----------GGRITVTLERDGDHVEITVEDNGPGIP-PEDLEKI----------FE 59
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1929623672 107 ESLGSDqaKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFW 154
Cdd:smart00387 60 PFFRTD--KRSRKIGGTGLGLSIVKKLVELHGGEISVESEPGGGTTFT 105
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
27-184 |
9.90e-07 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 47.75 E-value: 9.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 27 NKEIFLRELISNASDAADKLRFRAlsnpdlyegdGELRVRVSfDKDKRTLTISDNGVGMTRDEvIDHLGTiaksgtkSFL 106
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKA----------GEITVTLS-EGGELTLTVEDNGIGIPPED-LPRIFE-------PFS 61
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1929623672 107 ESLGSDQakdsqliGQFGVGFYSAFIVADKVtvrtraagekpeNGVFWESagegeytvadiTKEDRGTEITLHLREGE 184
Cdd:pfam02518 62 TADKRGG-------GGTGLGLSIVRKLVELL------------GGTITVE-----------SEPGGGTTVTLTLPLAQ 109
|
|
| HATPase_TopVIB-like |
cd16933 |
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ... |
21-221 |
6.85e-06 |
|
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain] Cd Length: 203 Bit Score: 47.34 E-value: 6.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 21 IHSLYsnkeIFLRELISNASDAADKlrfrALSNPDLYegdgelrVRVS-FDKDKRTLTISDNGVGMTRDEVidhlgtiak 99
Cdd:cd16933 17 IRSLY----TTVRELVENSLDATEE----AGILPDIK-------VEIEeIGKDHYKVIVEDNGPGIPEEQI--------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 100 sgTKSFLESLGSDQAKDSQLIGQFGVG-----FYSAFIVADKVTVRTRAAGEKPENGV---FWESAGEG---EYTVADIT 168
Cdd:cd16933 73 --PKVFGKVLYGSKYHNKQSRGQQGLGisaavLYSQMTTGKPVEIISSTKDSNYAYVVklmIDTDKNEPeilEKEEVENR 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1929623672 169 KEDRGTEITLHLREgedeflDDWRVRSIISKYSDH---IALPVEIEKREEKDGETV 221
Cdd:cd16933 151 YKWHGTRVELELEG------NWVAARSQILEYYKRtavIAPYAEIIFIVPDGETEV 200
|
|
| HATPase_MORC-like |
cd16931 |
Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger ... |
34-129 |
3.46e-04 |
|
Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains. In addition to the HATPase domain, MORC family proteins have a CW-type zinc finger domain containing four conserved cysteines and two conserved tryptophans, and coiled-coil domains at the carboxy-terminus. MORC1 has cross-species differential methylation in association with early life stress, and genome-wide association with major depressive disorder (MDD). MORC2 is involved in several nuclear processes, including transcription modulation and DNA damage repair, and exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY. MORC3 regulates p53, and is an antiviral factor which plays an important role during HSV-1 and HCMV infection, and is a positive regulator of influenza virus transcription. MORC4 is highly expressed in a subset of diffuse large B-cell lymphomas and has potential as a lymphoma biomarker.
Pssm-ID: 340408 [Multi-domain] Cd Length: 118 Bit Score: 40.47 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 34 ELISNASDA-ADKLRFRALSNPDLyegdgelrvrvsfdKDKRTLTISDNGVGMTRDEVIdHLGTIAKSGTKSFleslgsd 112
Cdd:cd16931 18 ELVDNARDAdATRLDIFIDDINLL--------------RGGFMLSFLDDGNGMTPEEAH-HMISFGFSDKRSD------- 75
|
90
....*....|....*..
gi 1929623672 113 qakDSQLIGQFGVGFYS 129
Cdd:cd16931 76 ---DHDHIGRYGNGFKS 89
|
|
| HATPase_c_3 |
pfam13589 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ... |
29-168 |
1.38e-03 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain] Cd Length: 135 Bit Score: 39.24 E-value: 1.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 29 EIFLRELISNASDAadklrfRALSnpdlyegdgelrVRVSFDKDKRT---LTISDNGVGMTRDEVIDHLGtIAKSGTKSf 105
Cdd:pfam13589 2 EGALAELIDNSIDA------DATN------------IKIEVNKNRGGgteIVIEDDGHGMSPEELINALR-LATSAKEA- 61
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1929623672 106 leslgsdqAKDSQLIGQFGVGFYSA-FIVADKVTVRTRAAGEKPENGVFWE-SAGEGEYTVADIT 168
Cdd:pfam13589 62 --------KRGSTDLGRYGIGLKLAsLSLGAKLTVTSKKEGKSSTLTLDRDkISNENDWLLPLLT 118
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
35-94 |
1.63e-03 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 40.94 E-value: 1.63e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 35 LISNASDAADKLRfralsnpdlyegDGELRVRVSFDKDKRTLTISDNGVGMTrDEVIDHL 94
Cdd:COG4191 264 LLINAIDAMEEGE------------GGRITISTRREGDYVVISVRDNGPGIP-PEVLERI 310
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
35-94 |
3.21e-03 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 40.33 E-value: 3.21e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1929623672 35 LISNASDAAdklrfralsnpdlyEGDGELRVRVSFDKDKRTLTISDNGVGMTrDEVIDHL 94
Cdd:COG5000 325 LLKNAIEAI--------------EEGGEIEVSTRREDGRVRIEVSDNGPGIP-EEVLERI 369
|
|
| |
