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Conserved domains on  [gi|1936948409|gb|QPI29405|]
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ABC transporter permease (plasmid) [Sinorhizobium meliloti]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-330 6.85e-100

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 296.98  E-value: 6.85e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYSDYIRSQLINQggasfeeadAQAQAYRKEHGLDKPLPIQYVNWITG 80
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATP---------EAIAALRAELGLDQPLLVQYLDWLGG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  81 IVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFLMALI 160
Cdd:COG0601    72 LL-RGDLGTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 161 IVYILVFHFNVSEInsfhsaryGGAPWSWDKFVDLIKHVW-PVVAIAtFGGLAYNMRVMRGNLLDTLNAQYVETARAKGL 239
Cdd:COG0601   151 LILLFAVKLGWLPV--------SGRVSPWEDFLDALRHLIlPALTLA-LGSLAGIARLTRSSMLEVLGQDYVRTARAKGL 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 240 SEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNIIAD 319
Cdd:COG0601   222 SERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVD 301

                         330
                  ....*....|.
gi 1936948409 320 MMLAALDPRVR 330
Cdd:COG0601   302 LLYALLDPRIR 312
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-330 6.85e-100

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 296.98  E-value: 6.85e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYSDYIRSQLINQggasfeeadAQAQAYRKEHGLDKPLPIQYVNWITG 80
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATP---------EAIAALRAELGLDQPLLVQYLDWLGG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  81 IVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFLMALI 160
Cdd:COG0601    72 LL-RGDLGTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 161 IVYILVFHFNVSEInsfhsaryGGAPWSWDKFVDLIKHVW-PVVAIAtFGGLAYNMRVMRGNLLDTLNAQYVETARAKGL 239
Cdd:COG0601   151 LILLFAVKLGWLPV--------SGRVSPWEDFLDALRHLIlPALTLA-LGSLAGIARLTRSSMLEVLGQDYVRTARAKGL 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 240 SEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNIIAD 319
Cdd:COG0601   222 SERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVD 301

                         330
                  ....*....|.
gi 1936948409 320 MMLAALDPRVR 330
Cdd:COG0601   302 LLYALLDPRIR 312
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-337 1.44e-44

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 154.86  E-value: 1.44e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYS-DYIRSQLINQGGASFEEAdaqaqayRKEHGLDKPLPIQYVNWIT 79
Cdd:PRK10352    1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPAlDYLRLSNLPPTPEMLAST-------RTMLGLDQPLYVQYGTWLW 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  80 GIVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFLMAl 159
Cdd:PRK10352   74 KAL-HLDFGISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLA- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 160 iivYILVFHFNVsEINSFHSARYGGApwswdkfvdliKH-VWPVVAIAtFGGLAYNMRVMRGNLLDTLNAQYVETARAKG 238
Cdd:PRK10352  152 ---FLLVMAFSV-YLQWLPAMGYGGW-----------QHiILPAVSIA-FMSLAINARLLRASMLEVAGQRHVTWARLRG 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 239 LSEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNIIA 318
Cdd:PRK10352  216 LSERQVERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIV 295

                         330
                  ....*....|....*....
gi 1936948409 319 DMMLAALDPRVRMGGGVYA 337
Cdd:PRK10352  296 DLLNAALDPRIRRHEGAHA 314
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 123-330 4.48e-20

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 86.20  E-value: 4.48e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 123 GIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFLMALIIVYilvfhfnvseinsfhsaryggapwsWDKFVDLIKHVWPV 202
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVV-------------------------IAILSILGHGILPA 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 203 VAIATFGGLAYnMRVMRGNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALP 282
Cdd:pfam00528  56 IILALLGWAGY-ARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP 134

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1936948409 283 TVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNIIADMMLAALDPRVR 330
Cdd:pfam00528 135 GLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 105-317 7.69e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 63.45  E-value: 7.69e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 105 LPRTLALALVCHILASVIGIAFGIIAAtRQYSWIDSLLSTVSFLGMTVPRFLMALIIVYILVFHFNVSEINSFhsarygg 184
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILA-RKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL------- 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 185 apwswdkfvdlikhVWPVVAIATFGGLAYNMRVMRgNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIMYQGVV 264
Cdd:cd06261    73 --------------GLPALILALLLIAPFARLIRR-AALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLA 137

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1936948409 265 LPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNII 317
Cdd:cd06261   138 FARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-330 6.85e-100

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 296.98  E-value: 6.85e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYSDYIRSQLINQggasfeeadAQAQAYRKEHGLDKPLPIQYVNWITG 80
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATP---------EAIAALRAELGLDQPLLVQYLDWLGG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  81 IVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFLMALI 160
Cdd:COG0601    72 LL-RGDLGTSFVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 161 IVYILVFHFNVSEInsfhsaryGGAPWSWDKFVDLIKHVW-PVVAIAtFGGLAYNMRVMRGNLLDTLNAQYVETARAKGL 239
Cdd:COG0601   151 LILLFAVKLGWLPV--------SGRVSPWEDFLDALRHLIlPALTLA-LGSLAGIARLTRSSMLEVLGQDYVRTARAKGL 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 240 SEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNIIAD 319
Cdd:COG0601   222 SERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVD 301

                         330
                  ....*....|.
gi 1936948409 320 MMLAALDPRVR 330
Cdd:COG0601   302 LLYALLDPRIR 312
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-337 1.44e-44

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 154.86  E-value: 1.44e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYS-DYIRSQLINQGGASFEEAdaqaqayRKEHGLDKPLPIQYVNWIT 79
Cdd:PRK10352    1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPAlDYLRLSNLPPTPEMLAST-------RTMLGLDQPLYVQYGTWLW 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  80 GIVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFLMAl 159
Cdd:PRK10352   74 KAL-HLDFGISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLA- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 160 iivYILVFHFNVsEINSFHSARYGGApwswdkfvdliKH-VWPVVAIAtFGGLAYNMRVMRGNLLDTLNAQYVETARAKG 238
Cdd:PRK10352  152 ---FLLVMAFSV-YLQWLPAMGYGGW-----------QHiILPAVSIA-FMSLAINARLLRASMLEVAGQRHVTWARLRG 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 239 LSEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNIIA 318
Cdd:PRK10352  216 LSERQVERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIV 295

                         330
                  ....*....|....*....
gi 1936948409 319 DMMLAALDPRVRMGGGVYA 337
Cdd:PRK10352  296 DLLNAALDPRIRRHEGAHA 314
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-330 2.68e-41

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 145.98  E-value: 2.68e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYSDYIRsqlinqggASFEEADAQAQAyrkEHGLDKPLPIQYVNWITG 80
Cdd:PRK09471    1 MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGER--------TLPPEVMANIEA---KYHLNDPIMTQYFSYLKQ 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  81 IVtRGDFGHSL-YYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFLMAL 159
Cdd:PRK09471   70 LA-HGDFGPSFkYKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAP 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 160 IIVYILVFHFNVSEINSFHsaryGGAPwswdKFVDLikhvwPVVAIaTFGGLAYNMRVMRGNLLDTLNAQYVETARAKGL 239
Cdd:PRK09471  149 LLVLIFAITLHWLPGGGWN----GGAL----KFMIL-----PMVAL-SLAYIASIARITRGSMIEVLHSNFIRTARAKGL 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 240 SEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMWVGDvyvtatFMLVLSATLIVG----- 314
Cdd:PRK09471  215 PMRRIILRHALKPALLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRD------YSLVLSLTILVGaltil 288

                         330
                  ....*....|....*..
gi 1936948409 315 -NIIADMMLAALDPRVR 330
Cdd:PRK09471  289 fNAIVDVLYAVIDPKIR 305
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-330 9.91e-41

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 144.47  E-value: 9.91e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYSDYIRSQlinqggasfeEADAQAQAY-RKEHGLDKPLPIQYVNWIT 79
Cdd:PRK15081    1 MLNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAGP----------EADAQVVALvRQQLGLDQPLPHQFWHYIS 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  80 GIVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFlmAL 159
Cdd:PRK15081   71 NAL-QGDFGTSMVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAF--AL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 160 IIVYILVFHFNVSEINSFhsarygGAPwSWDKFVdlikhvwpVVAIATFGGLAYNM-RVMRGNLLDTLNAQYVETARAKG 238
Cdd:PRK15081  148 GMLLMQVFSVELGWLPTV------GAD-SWQHYI--------LPSLTLGAAVAAVMaRFTRASFVEVLSEDYMRTARAKG 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 239 LSEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNIIA 318
Cdd:PRK15081  213 VSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVV 292

                         330
                  ....*....|..
gi 1936948409 319 DMMLAALDPRVR 330
Cdd:PRK15081  293 DVLYAAINPAIR 304
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
1-330 1.80e-31

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 120.69  E-value: 1.80e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDysdyirSQLINQGGASFE-EADAQAQAyrkEHGLDKPLPIQYVNWIT 79
Cdd:PRK10914    1 MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGD------PVMIMAGERGISpERHAQLLA---ELGLDKPMWQQYLHYIW 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  80 GIVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFLMAL 159
Cdd:PRK10914   72 GVM-HGDLGISLKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGM 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 160 IIVYILVFHFNVSEInsfhSARYGGAPWSWDK-------------------FVDLIKH-VWPVVAIATFGgLAYNMRVMR 219
Cdd:PRK10914  151 MLIMLVSVHWNLTPV----SGRVSDMVFLDDSnpltgfmlidtaiwgedgnFIDAVAHmILPAIVLGTIP-LAVIVRMTR 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 220 GNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYV 299
Cdd:PRK10914  226 SSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPV 305

                         330       340       350
                  ....*....|....*....|....*....|.
gi 1936948409 300 TATFMLVLSATLIVGNIIADMMLAALDPRVR 330
Cdd:PRK10914  306 VQGGVLLVATMIILVNLLVDLLYGVVNPRIR 336
YejB COG4174
ABC-type microcin C transport system, permease component YejB [Secondary metabolites ...
 1-329 1.08e-29

ABC-type microcin C transport system, permease component YejB [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443333 [Multi-domain]  Cd Length: 363  Bit Score: 116.44  E-value: 1.08e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYSDYIRSQLINQGGASFEEADAQAQ------------AYR------- 61
Cdd:COG4174     1 MGAYILRRLLLMIPTLLGIMLINFVIVQFAPGGPVEQVIAQLQGTGGGATGRISGGGGdagggaaagggsKYRgargldp 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  62 -------KEHGLDKPLPIQYVNWITGIVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQ 134
Cdd:COG4174    81 efiaeleKQYGFDKPAHERFLLMLKNYL-RFDFGESYFRDISVIDLILEKLPVSISLGLWSTLLTYLISIPLGIRKAVRD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 135 YSWIDSLLSTVSFLGMTVPRFLMAliIVYILVF----HFNVSEINSFHSARYGGAPWsWDKFVDLIKH-VWPVVAIaTFG 209
Cdd:COG4174   160 GSRFDVWTSTVIIVGYAIPGFLFA--ILLIVLFaggsYFDWFPLRGLTSDNWDQLSW-WGKILDYLWHlTLPVTAM-VIG 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 210 GLAYNMRVMRGNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIM-YQGVVLPYMLTGE--IETaiIFALPTVG- 285
Cdd:COG4174   236 GFATLTLLTKNSFLDEIRKQYVLTARAKGLSERRVLYGHVFRNAMLIVIAgFPAAFIGAFFTGSllIET--IFSLDGLGl 313

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1936948409 286 -----------PAIVGSMWVgdvyvtatFmlvlsaTLI--VGNIIADMMLAALDPRV 329
Cdd:COG4174   314 lgfeavvnrdyPVVFGTLYI--------F------TLIglVLKLISDLTYVLVDPRI 356
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 4-333 1.39e-24

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 102.52  E-value: 1.39e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   4 FLLVRIASAIPVLLVLSVVTFGIIQAPPGDYSDYIRSQLINQGGASFeeADAQAQAYR-----------KEHGLDKPLPI 72
Cdd:PRK15133   24 FFIVQIAPGGPVDQAIAAIEFGQAGGLPGAGGEGVRASHAQTGVGNI--SDSNYRGGRgldpeviaeitHRYGFDKPLHE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  73 QYVNWITGIVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLGMTV 152
Cdd:PRK15133  102 RYFKMLWDYI-RFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSRFDVWSSAFIIIGYAI 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 153 PRFLMALIIVYILV--FHFNVSEINSFHSARYGGAPWsWDKFVDLIKHV-WPVVAiATFGGLAYNMRVMRGNLLDTLNAQ 229
Cdd:PRK15133  181 PAFLFAILLIVFFAggSYFDLFPLRGLVSANFDSLPW-YQKITDYLWHItLPVLA-TVIGGFAALTMLTKNSFLDEIRKQ 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 230 YVETARAKGLSEGAVVMRHAVPNALHPLIM-YQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYVTATFMLVLS 308
Cdd:PRK15133  259 YVVTARAKGVSEKNILWKHVFRNAMLLVIAgFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTLYIFT 338

                         330       340
                  ....*....|....*....|....*
gi 1936948409 309 ATLIVGNIIADMMLAALDPRVRMGG 333
Cdd:PRK15133  339 LIGLLLNIVSDISYTLVDPRIDFEG 363
PRK15110 PRK15110
peptide ABC transporter permease SapB;
70-327 2.29e-23

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 98.22  E-value: 2.29e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  70 LPIQYVNWITGIVtRGDFGHSLYYNKPVADVVGERLPRTLALALVCHILASVIGIAFGIIAATRQYSWIDSLLSTVSFLG 149
Cdd:PRK15110   40 LWDAWVFWFNGLL-HWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLG 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 150 MTVPRFLMALIIVYILVFH-------------FNVSEINSFH--SARYGGAPWSWDKFVDLIKH-VWPVVAIATfGGLAY 213
Cdd:PRK15110  119 FSIPVFWLALLLTLFFSLTlgwlpvsgrfdllYEVKPVTGFAliDAWLSDSPWRDEMIMSAIRHmILPVITLAV-APTTE 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 214 NMRVMRGNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALPTVGPAIVGSMW 293
Cdd:PRK15110  198 VIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIR 277

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1936948409 294 VGDVYVTATFMLVLSATLIVGNIIADMMLAALDP 327
Cdd:PRK15110  278 QQDYAAISAGVMVVGSLVIIVNVLSDILGAMANP 311
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 123-330 4.48e-20

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 86.20  E-value: 4.48e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 123 GIAFGIIAATRQYSWIDSLLSTVSFLGMTVPRFLMALIIVYilvfhfnvseinsfhsaryggapwsWDKFVDLIKHVWPV 202
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVV-------------------------IAILSILGHGILPA 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 203 VAIATFGGLAYnMRVMRGNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIFALP 282
Cdd:pfam00528  56 IILALLGWAGY-ARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP 134

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1936948409 283 TVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNIIADMMLAALDPRVR 330
Cdd:pfam00528 135 GLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 1-112 1.46e-17

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 77.26  E-value: 1.46e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   1 MFRFLLVRIASAIPVLLVLSVVTFGIIQAPPGDYSdyirsqLINQGGASFEEADAQAqayRKEHGLDKPLPIQYVNWITG 80
Cdd:pfam19300   1 MLRFLVRRTLGAVVILLIISAVTFFLFYAIPRDPA------RLACGKNCTPETLALI---RHNLGLDKPIPVQYWHFLSG 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1936948409  81 IVTRGDF-----------GHSLYYNKPVADVVGERLPRTLALA 112
Cdd:pfam19300  72 IFAGRDFgavghcpapclGYSFANNEPVWDTIMDRFPTTLSLA 114
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 105-317 7.69e-12

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 63.45  E-value: 7.69e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 105 LPRTLALALVCHILASVIGIAFGIIAAtRQYSWIDSLLSTVSFLGMTVPRFLMALIIVYILVFHFNVSEINSFhsarygg 184
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILA-RKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL------- 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 185 apwswdkfvdlikhVWPVVAIATFGGLAYNMRVMRgNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIMYQGVV 264
Cdd:cd06261    73 --------------GLPALILALLLIAPFARLIRR-AALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLA 137

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1936948409 265 LPYMLTGEIETAIIFALPTVGPAIVGSMWVGDVYVTATFMLVLSATLIVGNII 317
Cdd:cd06261   138 FARALGEFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 108-272 1.23e-10

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 61.28  E-value: 1.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 108 TLALALVCHILASVIGIAFGIIAATRQySWIDSLLSTVSFLGMTVPRFLMALIIVYILvfhfnvseinsfhsaryGGAPW 187
Cdd:COG1173    81 SLLVGLLAVLIALVIGVLLGLLAGYFG-GWVDAVLMRLVDVLLAFPSLLLAIALVAVL-----------------GPGLL 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 188 SwdkfvdlikhvwpVVAIATFGGLAYNMRVMRGNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIMYQGVVLPY 267
Cdd:COG1173   143 N-------------VILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIAS 209


                  ....*
gi 1936948409 268 MLTGE 272
Cdd:COG1173   210 AILAE 214
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 5-327 2.52e-07

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 51.52  E-value: 2.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409   5 LLVRIASA--IPVLLVLSVVTFGIIQAPPGDYSD-YIRSQLINQGGASFeeADAQAQAYRKEHGLDKPLPI--QYVNWIT 79
Cdd:PRK15021   47 LLVRYDGSwyFPLLKNYSESDFGGPLASQADYQDpWLKQRLENNGWVLW--APIRFGATSINFATDKPFPSppSRQNWLG 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409  80 GIVTRGDFGHSLYYnkpvadvvGERLprTLALALVCHILASVIGIAFGIIAAtrQYSwidsllSTVSFLGMTVPRFLMAL 159
Cdd:PRK15021  125 TDANGGDVLARILY--------GTRI--SVLFGLMLTLCSSVMGVLAGALQG--YYG------GKVDLWGQRFIEVWSGM 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 160 IIVYILVFHFNVSEINsfhsaryggapwswdkfvdlikhVWPVVAIATFGGLAYNMRVMRGNLLDTLNAQYVETARAKGL 239
Cdd:PRK15021  187 PTLFLIILLSSVVQPN-----------------------FWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGV 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 240 SEGAVVMRHAVPNALHPLIMYqgvvLPYMLTGEIETA-----IIFALPTVGPAI----------VGSMWVGdvyVTA--T 302
Cdd:PRK15021  244 SDRSIILRHMLPNAMVATLTF----LPFILCSSITTLtsldfLGFGLPLGSPSLgelllqgknnLQAPWLG---ITAflS 316

                         330       340
                  ....*....|....*....|....*
gi 1936948409 303 FMLVLSATLIVGNIIADmmlaALDP 327
Cdd:PRK15021  317 VAILLSLLIFIGEAVRD----AFDP 337
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 100-280 7.07e-05

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 43.95  E-value: 7.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 100 VVGERLprTLALALVCHILASVIGIAFGIIAATRQySWIDSLLSTVSFLGMTVPRFLMALIIVYILvfhfNVSEINSfhs 179
Cdd:PRK15082   96 LVGARI--SLAAGFFSVAIGAAIGTVLGLLAGYYE-GWWDRIIMRICDVLFAFPGILLAIAVVAIL----GSGMANV--- 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 180 aryggapwswdkfvdlikhvwpVVAIATFGGLAYnMRVMRGNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIM 259
Cdd:PRK15082  166 ----------------------IIAVAIFSIPAF-ARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVV 222

                         170       180
                  ....*....|....*....|.
gi 1936948409 260 YqgvvlpymLTGEIETAIIFA 280
Cdd:PRK15082  223 Y--------FTMRIGTSIITA 235
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 216-330 2.85e-04

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 42.13  E-value: 2.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1936948409 216 RVMRGNLLDTLNAQYVETARAKGLSEGAVVMRHAVPNALHPLIMYQGVVLPYMLTGEIETAIIfALPTVGPAivgSMWVG 295
Cdd:PRK15406  181 RIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFL-GLGTQEPL---SSWGA 256

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1936948409 296 DVYVTATFMLV-----------LSATLIVGNIIADMMLAALDPRVR 330
Cdd:PRK15406  257 LLSDGANSMEVspwlllfpagfLVVTLFCFNFIGDGLRDALDPKDR 302
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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