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Conserved domains on  [gi|1972745132|gb|QRE25449|]
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sugar transferase, partial [Flavobacterium psychrophilum]

Protein Classification

sugar transferase( domain architecture ID 10005412)

sugar transferase catalyzes the transfer of a sugar from a donor such as UDP-glucose or UDP-galactose, to a lipid carrier such as undecaprenyl phosphate

EC:  2.-.-.-
Gene Ontology:  GO:0016780|GO:0000271|GO:0005886
PubMed:  29769739
SCOP:  4007826

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WcaJ COG2148
Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane ...
 1-173 9.18e-86

Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 441751 [Multi-domain]  Cd Length: 322  Bit Score: 254.66  E-value: 9.18e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   1 MYKLFIKQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTMNEAKDAQGNL---LSDA 77
Cdd:COG2148   133 GYQRVLKRLFDIVLALLGLILLSPLLLLIALAIKLDSGGPVFFRQERVGRNGRPFTIYKFRTMRVDAEKLLGAvfkLKND 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  78 ERLTPIGKFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQYLHLYN-NFQNRRHEVKPGITGWAQVNGRNAISWDKKFEL 156
Cdd:COG2148   213 PRITRVGRFLRKTSLDELPQLWNVLKGDMSLVGPRPELPEEVELYEeEEYRRRLLVKPGITGLAQVNGRNGETFEERVEL 292

                         170
                  ....*....|....*..
gi 1972745132 157 DVWYVDHISFSLDFKIL 173
Cdd:COG2148   293 DLYYIENWSLWLDLKIL 309
 
Name Accession Description Interval E-value
WcaJ COG2148
Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane ...
 1-173 9.18e-86

Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441751 [Multi-domain]  Cd Length: 322  Bit Score: 254.66  E-value: 9.18e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   1 MYKLFIKQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTMNEAKDAQGNL---LSDA 77
Cdd:COG2148   133 GYQRVLKRLFDIVLALLGLILLSPLLLLIALAIKLDSGGPVFFRQERVGRNGRPFTIYKFRTMRVDAEKLLGAvfkLKND 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  78 ERLTPIGKFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQYLHLYN-NFQNRRHEVKPGITGWAQVNGRNAISWDKKFEL 156
Cdd:COG2148   213 PRITRVGRFLRKTSLDELPQLWNVLKGDMSLVGPRPELPEEVELYEeEEYRRRLLVKPGITGLAQVNGRNGETFEERVEL 292

                         170
                  ....*....|....*..
gi 1972745132 157 DVWYVDHISFSLDFKIL 173
Cdd:COG2148   293 DLYYIENWSLWLDLKIL 309
Bac_transf pfam02397
Bacterial sugar transferase; This Pfam family represents a conserved region from a number of ...
 7-173 7.89e-81

Bacterial sugar transferase; This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.


Pssm-ID: 460547 [Multi-domain]  Cd Length: 180  Bit Score: 236.87  E-value: 7.89e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   7 KQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTMNEAKDAQGNL--LSDAERLTPIG 84
Cdd:pfam02397   1 KRLFDIVLSLLGLILLSPLLLLIAIAIKLLSGGPVFFRQERVGKNGKPFTIYKFRTMVVDAEKRGPLfkLKNDPRITRVG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  85 KFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQY-LHLYNNFQNRRHEVKPGITGWAQVN-GRNAISWDKKFELDVWYVD 162
Cdd:pfam02397  81 RFLRKTSLDELPQLINVLKGDMSLVGPRPELPEFeYELYERDQRRRLSVKPGITGLAQVNgGRSELSFEEKLELDLYYIE 160

                         170
                  ....*....|.
gi 1972745132 163 HISFSLDFKIL 173
Cdd:pfam02397 161 NWSLWLDLKIL 171
EPS_sugtrans TIGR03025
exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Members of this family ...
 4-174 9.41e-66

exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Members of this family are generally found near other genes involved in the biosynthesis of a variety of exopolysaccharides. These proteins consist of two fused domains, an N-terminal hydrophobic domain of generally low conservation and a highly conserved C-terminal sugar transferase domain (pfam02397). Characterized and partially characterized members of this subfamily include Salmonella WbaP (originally RfbP), E. coli WcaJ, Methylobacillus EpsB, Xanthomonas GumD, Vibrio CpsA, Erwinia AmsG, Group B Streptococcus CpsE (originally CpsD), and Streptococcus suis Cps2E. Each of these is believed to act in transferring the sugar from, for instance, UDP-glucose or UDP-galactose, to a lipid carrier such as undecaprenyl phosphate as the first (priming) step in the synthesis of an oligosaccharide "block". This function is encoded in the C-terminal domain. The liposaccharide is believed to be subsequently transferred through a "flippase" function from the cytoplasmic to the periplasmic face of the inner membrane by the N-terminal domain. Certain closely related transferase enzymes, such as Sinorhizobium ExoY and Lactococcus EpsD, lack the N-terminal domain and are not found by this model.


Pssm-ID: 274398 [Multi-domain]  Cd Length: 445  Bit Score: 207.44  E-value: 9.41e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   4 LFIKQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTMNEAKDAQGNLL---SDAERL 80
Cdd:TIGR03025 255 RALKRLFDIVLSLLALLLLSPLMLAIALAIKLDSPGPVFFRQERVGLNGKPFTVYKFRSMRVDAEEGGGPVqatKNDPRI 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  81 TPIGKFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQYLHLY---NNFQNRRHEVKPGITGWAQVNGRNAIS-WDKKFEL 156
Cdd:TIGR03025 335 TRVGRFLRRTSLDELPQLFNVLKGDMSLVGPRPERPAEVEKYeqeIPGYMLRHKVKPGITGWAQVSGRGETStMEERVEY 414

                         170
                  ....*....|....*...
gi 1972745132 157 DVWYVDHISFSLDFKILY 174
Cdd:TIGR03025 415 DLYYIENWSLWLDLKILL 432
PRK15204 PRK15204
undecaprenyl-phosphate galactose phosphotransferase; Provisional
 5-174 1.91e-34

undecaprenyl-phosphate galactose phosphotransferase; Provisional


Pssm-ID: 185126 [Multi-domain]  Cd Length: 476  Bit Score: 125.89  E-value: 1.91e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   5 FIKQIIDFLVSLVAVVILTPLLLIITIGLffANNGKPFFF-QLRPGKNGKIFKIIKFKTM--NEAKDAQGNLLSDA---- 77
Cdd:PRK15204  278 FLKRTFDIVCSIMILIIASPLMIYLWYKV--TRDGGPAIYgHQRVGRHGKLFPCYKFRSMvmNSQEVLKELLANDPiara 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  78 -----------ERLTPIGKFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQYLHLYNNFQNRRHEVKPGITGWAQVNGRN 146
Cdd:PRK15204  356 ewekdfklkndPRITAVGRFIRKTSLDELPQLFNVLKGDMSLVGPRPIVSDELERYCDDVDYYLMAKPGMTGLWQVSGRN 435

                         170       180
                  ....*....|....*....|....*...
gi 1972745132 147 AISWDKKFELDVWYVDHISFSLDFKILY 174
Cdd:PRK15204  436 DVDYDTRVYFDSWYVKNWTLWNDIAILF 463
 
Name Accession Description Interval E-value
WcaJ COG2148
Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane ...
 1-173 9.18e-86

Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid) [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441751 [Multi-domain]  Cd Length: 322  Bit Score: 254.66  E-value: 9.18e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   1 MYKLFIKQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTMNEAKDAQGNL---LSDA 77
Cdd:COG2148   133 GYQRVLKRLFDIVLALLGLILLSPLLLLIALAIKLDSGGPVFFRQERVGRNGRPFTIYKFRTMRVDAEKLLGAvfkLKND 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  78 ERLTPIGKFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQYLHLYN-NFQNRRHEVKPGITGWAQVNGRNAISWDKKFEL 156
Cdd:COG2148   213 PRITRVGRFLRKTSLDELPQLWNVLKGDMSLVGPRPELPEEVELYEeEEYRRRLLVKPGITGLAQVNGRNGETFEERVEL 292

                         170
                  ....*....|....*..
gi 1972745132 157 DVWYVDHISFSLDFKIL 173
Cdd:COG2148   293 DLYYIENWSLWLDLKIL 309
Bac_transf pfam02397
Bacterial sugar transferase; This Pfam family represents a conserved region from a number of ...
 7-173 7.89e-81

Bacterial sugar transferase; This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.


Pssm-ID: 460547 [Multi-domain]  Cd Length: 180  Bit Score: 236.87  E-value: 7.89e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   7 KQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTMNEAKDAQGNL--LSDAERLTPIG 84
Cdd:pfam02397   1 KRLFDIVLSLLGLILLSPLLLLIAIAIKLLSGGPVFFRQERVGKNGKPFTIYKFRTMVVDAEKRGPLfkLKNDPRITRVG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  85 KFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQY-LHLYNNFQNRRHEVKPGITGWAQVN-GRNAISWDKKFELDVWYVD 162
Cdd:pfam02397  81 RFLRKTSLDELPQLINVLKGDMSLVGPRPELPEFeYELYERDQRRRLSVKPGITGLAQVNgGRSELSFEEKLELDLYYIE 160

                         170
                  ....*....|.
gi 1972745132 163 HISFSLDFKIL 173
Cdd:pfam02397 161 NWSLWLDLKIL 171
EPS_sugtrans TIGR03025
exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Members of this family ...
 4-174 9.41e-66

exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Members of this family are generally found near other genes involved in the biosynthesis of a variety of exopolysaccharides. These proteins consist of two fused domains, an N-terminal hydrophobic domain of generally low conservation and a highly conserved C-terminal sugar transferase domain (pfam02397). Characterized and partially characterized members of this subfamily include Salmonella WbaP (originally RfbP), E. coli WcaJ, Methylobacillus EpsB, Xanthomonas GumD, Vibrio CpsA, Erwinia AmsG, Group B Streptococcus CpsE (originally CpsD), and Streptococcus suis Cps2E. Each of these is believed to act in transferring the sugar from, for instance, UDP-glucose or UDP-galactose, to a lipid carrier such as undecaprenyl phosphate as the first (priming) step in the synthesis of an oligosaccharide "block". This function is encoded in the C-terminal domain. The liposaccharide is believed to be subsequently transferred through a "flippase" function from the cytoplasmic to the periplasmic face of the inner membrane by the N-terminal domain. Certain closely related transferase enzymes, such as Sinorhizobium ExoY and Lactococcus EpsD, lack the N-terminal domain and are not found by this model.


Pssm-ID: 274398 [Multi-domain]  Cd Length: 445  Bit Score: 207.44  E-value: 9.41e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   4 LFIKQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTMNEAKDAQGNLL---SDAERL 80
Cdd:TIGR03025 255 RALKRLFDIVLSLLALLLLSPLMLAIALAIKLDSPGPVFFRQERVGLNGKPFTVYKFRSMRVDAEEGGGPVqatKNDPRI 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  81 TPIGKFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQYLHLY---NNFQNRRHEVKPGITGWAQVNGRNAIS-WDKKFEL 156
Cdd:TIGR03025 335 TRVGRFLRRTSLDELPQLFNVLKGDMSLVGPRPERPAEVEKYeqeIPGYMLRHKVKPGITGWAQVSGRGETStMEERVEY 414

                         170
                  ....*....|....*...
gi 1972745132 157 DVWYVDHISFSLDFKILY 174
Cdd:TIGR03025 415 DLYYIENWSLWLDLKILL 432
WcaJ_sugtrans TIGR03023
Undecaprenyl-phosphate glucose phosphotransferase; This family of proteins encompasses the E. ...
 5-174 1.09e-53

Undecaprenyl-phosphate glucose phosphotransferase; This family of proteins encompasses the E. coli WcaJ protein involved in colanic acid biosynthesis, the Methylobacillus EpsB protein involved in methanolan biosynthesis, as well as the GumD protein involved in the biosynthesis of xanthan. All of these are closely related to the well-characterized WbaP (formerly RfbP) protein, which is the first enzyme in O-antigen biosynthesis in Salmonella typhimurium. The enzyme transfers galactose from UDP-galactose (NOTE: not glucose) to a polyprenyl carrier (utilizing the highly conserved C-terminal sugar transferase domain, pfam02397) a reaction which takes place at the cytoplasmic face of the inner membrane. The N-terminal hydrophobic domain is then believed to facilitate the "flippase" function of transferring the liposaccharide unit from the cytoplasmic face to the periplasmic face of the inner membrane. Most of these genes are found within large operons dedicated to the production of complex exopolysaccharides such as the enterobacterial O-antigen. Colanic acid biosynthesis utilizes a glucose-undecaprenyl carrier, knockout of EpsB abolishes incorporation of UDP-glucose into the lipid phase, and the C-terminal portion of GumD has been shown to be responsible for the glucosyl-1-transferase activity.


Pssm-ID: 274396 [Multi-domain]  Cd Length: 450  Bit Score: 176.24  E-value: 1.09e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   5 FIKQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTM----NEAKDAQGnLLSDAeRL 80
Cdd:TIGR03023 258 FIKRAFDIVLALLVLLLLSPLLLLIAIAIKLTSPGPVLFRQERYGLDGRPFMVYKFRSMrvhaEGDGVTQA-TRNDP-RV 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  81 TPIGKFVRKTSLDEIPQLLNVLNGDMSLIGPRP-----------LLPQYLHlynnfqnrRHEVKPGITGWAQVNG-RNAI 148
Cdd:TIGR03023 336 TRVGAFLRRTSLDELPQFFNVLKGDMSIVGPRPhavahneqyrkLIPGYML--------RHKVKPGITGWAQVNGlRGET 407

                         170       180       190
                  ....*....|....*....|....*....|
gi 1972745132 149 SWDKKF----ELDVWYVDHISFSLDFKILY 174
Cdd:TIGR03023 408 DTLEKMekrvEYDLYYIENWSLWLDLKIIL 437
EpsB_2 TIGR03013
sugar transferase, PEP-CTERM system associated; Members of this protein family belong to the ...
 5-173 5.45e-43

sugar transferase, PEP-CTERM system associated; Members of this protein family belong to the family of bacterial sugar transferases (pfam02397). Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria (notable exceptions appear to include Magnetococcus sp. MC-1 and Myxococcus xanthus DK 1622 ). These genes are generally found near one or more of the PrsK, PrsR or PrsT genes that have been related to the PEP-CTERM system by phylogenetic profiling methods. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species. These proteins are homologs of the EpsB protein found in Methylobacillus sp. strain 12S, which is also associated with a PEP-CTERM system, but of a distinct type. A name which appears attached to a number of genes (by transitive annotation) in this family is "undecaprenyl-phosphate galactose phosphotransferase", which comes from relatively distant characterized enterobacterial homologs, and is considerably more specific than warranted from the currently available evidence.


Pssm-ID: 274390 [Multi-domain]  Cd Length: 442  Bit Score: 147.92  E-value: 5.45e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   5 FIKQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTMNEAKDAQGNL--LSDAERLTP 82
Cdd:TIGR03013 254 ITKRSFDVVASLILLILTLPVMLFTALAIKLESGGPVLYRQERVGLNGRPFNLIKFRSMRADAEKNGAVwaQKDDPRVTR 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  83 IGKFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQYLH-LYNN--FQNRRHEVKPGITGWAQVNGRNAISWD---KKFEL 156
Cdd:TIGR03013 334 VGRFLRKTRIDELPQIFNVLRGDMSFVGPRPERPEFVEkLSEEipYYNERHRVKPGITGWAQIKYPYGASVAdakEKLRY 413

                         170
                  ....*....|....*..
gi 1972745132 157 DVWYVDHISFSLDFKIL 173
Cdd:TIGR03013 414 DLYYIKNMSLLLDLIIL 430
PRK15204 PRK15204
undecaprenyl-phosphate galactose phosphotransferase; Provisional
 5-174 1.91e-34

undecaprenyl-phosphate galactose phosphotransferase; Provisional


Pssm-ID: 185126 [Multi-domain]  Cd Length: 476  Bit Score: 125.89  E-value: 1.91e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   5 FIKQIIDFLVSLVAVVILTPLLLIITIGLffANNGKPFFF-QLRPGKNGKIFKIIKFKTM--NEAKDAQGNLLSDA---- 77
Cdd:PRK15204  278 FLKRTFDIVCSIMILIIASPLMIYLWYKV--TRDGGPAIYgHQRVGRHGKLFPCYKFRSMvmNSQEVLKELLANDPiara 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  78 -----------ERLTPIGKFVRKTSLDEIPQLLNVLNGDMSLIGPRPLLPQYLHLYNNFQNRRHEVKPGITGWAQVNGRN 146
Cdd:PRK15204  356 ewekdfklkndPRITAVGRFIRKTSLDELPQLFNVLKGDMSLVGPRPIVSDELERYCDDVDYYLMAKPGMTGLWQVSGRN 435

                         170       180
                  ....*....|....*....|....*...
gi 1972745132 147 AISWDKKFELDVWYVDHISFSLDFKILY 174
Cdd:PRK15204  436 DVDYDTRVYFDSWYVKNWTLWNDIAILF 463
PRK10124 PRK10124
putative UDP-glucose lipid carrier transferase; Provisional
 6-174 2.79e-34

putative UDP-glucose lipid carrier transferase; Provisional


Pssm-ID: 182254 [Multi-domain]  Cd Length: 463  Bit Score: 125.22  E-value: 2.79e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132   6 IKQIIDFLVSLVAVVILTPLLLIITIGLFFANNGKPFFFQLRPGKNGKIFKIIKFKTMNEAKDaqGNLLSDAE----RLT 81
Cdd:PRK10124  272 LKRAEDIVLASLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGKPIKVWKFRSMKVMEN--DKVVTQATqndpRVT 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972745132  82 PIGKFVRKTSLDEIPQLLNVLNGDMSLIGPRPLL----PQYLHLYNNFQnRRHEVKPGITGWAQVNGrnaisW------- 150
Cdd:PRK10124  350 KVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAvahnEQYRQLIEGYM-LRHKVKPGITGWAQING-----Wrgetdtl 423

                         170       180
                  ....*....|....*....|....*..
gi 1972745132 151 ---DKKFELDVWYVDHISFSLDFKILY 174
Cdd:PRK10124  424 ekmEKRVEFDLEYIREWSVWFDIKIVF 450
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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