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Conserved domains on  [gi|1988060770|gb|QRT83135|]
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IS481 family transposase [Bordetella pertussis]

Protein Classification

transposase family protein( domain architecture ID 1750099)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0046872|GO:0003676|GO:0006310
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
transpos_IS481 NF033577
IS481 family transposase; null
13-305 2.97e-109

IS481 family transposase; null


:

Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 318.77  E-value: 2.97e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  13 GRALLVNRVMQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRPHRSPKACAPEQVEHFAQQRRQ-RLPLWR 91
Cdd:NF033577    1 GRLELVRLVLEDGWSVREAARRFGISRKTVYKWLKRYRAGGEEGLIDRSRRPHRSPRRTSPETEARILALRRElRLGPRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  92 IAREAGR-----SLATVARYMERIGLSRLASLEPP-APVRRYERASPGELLHIDTKRLGRIRGVGhritgdraqnrnrgi 165
Cdd:NF033577   81 IAYELERqgpgvSRSTVHRILRRHGLSRLRALDRKtGKVKRYERAHPGELWHIDIKKLGRIPDVG--------------- 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 166 gWDAVHLAIDDFSRVSFARILDDEGGDQCAEFLRQAtayYASLGVRIDRVMTDNGSGYVSRT--FRAVCVELGIRHIRTR 243
Cdd:NF033577  146 -RLYLHTAIDDHSRFAYAELYPDETAETAADFLRRA---FAEHGIPIRRVLTDNGSEFRSRAhgFELALAELGIEHRRTR 221
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1988060770 244 PYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSALGHQPPITRI 305
Cdd:NF033577  222 PYHPQTNGKVERFHRTLKDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPAERF 283
 
Name Accession Description Interval E-value
transpos_IS481 NF033577
IS481 family transposase; null
13-305 2.97e-109

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 318.77  E-value: 2.97e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  13 GRALLVNRVMQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRPHRSPKACAPEQVEHFAQQRRQ-RLPLWR 91
Cdd:NF033577    1 GRLELVRLVLEDGWSVREAARRFGISRKTVYKWLKRYRAGGEEGLIDRSRRPHRSPRRTSPETEARILALRRElRLGPRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  92 IAREAGR-----SLATVARYMERIGLSRLASLEPP-APVRRYERASPGELLHIDTKRLGRIRGVGhritgdraqnrnrgi 165
Cdd:NF033577   81 IAYELERqgpgvSRSTVHRILRRHGLSRLRALDRKtGKVKRYERAHPGELWHIDIKKLGRIPDVG--------------- 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 166 gWDAVHLAIDDFSRVSFARILDDEGGDQCAEFLRQAtayYASLGVRIDRVMTDNGSGYVSRT--FRAVCVELGIRHIRTR 243
Cdd:NF033577  146 -RLYLHTAIDDHSRFAYAELYPDETAETAADFLRRA---FAEHGIPIRRVLTDNGSEFRSRAhgFELALAELGIEHRRTR 221
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1988060770 244 PYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSALGHQPPITRI 305
Cdd:NF033577  222 PYHPQTNGKVERFHRTLKDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPAERF 283
LZ_Tnp_IS481 pfam13011
leucine-zipper of insertion element IS481; This is the upstream region of the conjoined ORF AB ...
1-85 7.50e-43

leucine-zipper of insertion element IS481; This is the upstream region of the conjoined ORF AB of insertion element 481. The significance of IS481 in the detection of Bordetella pertussis is discussed in. The B portion of the ORF AB carries the transposase activity in family rve, pfam00665.


Pssm-ID: 289759 [Multi-domain]  Cd Length: 85  Bit Score: 142.49  E-value: 7.50e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770   1 MNNHKHARLTRLGRALLVNRVMQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRPHRSPKACAPEQVEHFA 80
Cdd:pfam13011   1 MNNHGHARLTRHGRALLVNRVMEDNRPMAHAAQAAGVSLQCAHKWLARFRAEGLDGLLDRSSRPHRSPKACAPEQEEAFA 80

                  ....*
gi 1988060770  81 QQRRQ 85
Cdd:pfam13011  81 EARAQ 85
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
43-302 5.07e-24

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 99.46  E-value: 5.07e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  43 YKWLARFRSEGLDGLLDRSSRPHRSPKACAPEQVEHFAQQRRQRLPLWRIAREAGR-----SLATVARYMERIGL----- 112
Cdd:COG2801    43 LRLLRRRRARSRRRRRLRRPRSYRADEDAELLERIKEIFAESPRYGYRRITAELRRegiavNRKRVRRLMRELGLqarrr 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 113 ------SRLASLEPPAPVRRYERASPGELLHIDtkrlgrirgvghrITGDRAQNrnrgiGWDAVHLAIDDFSR--VSFaR 184
Cdd:COG2801   123 rkkkytTYSGHGGPIAPNLLFTATAPNQVWVTD-------------ITYIPTAE-----GWLYLAAVIDLFSReiVGW-S 183
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 185 ILDDEGGDQCAEFLRQATAYYASLGVRIdrVMTDNGSGYVSRTFRAVCVELGIRHIRTRPYTPKTNGKAERLVQTCLREW 264
Cdd:COG2801   184 VSDSMDAELVVDALEMAIERRGPPKPLI--LHSDNGSQYTSKAYQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYEL 261
                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1988060770 265 AYARPYTSSAERQAALQPFIDRYNWCRPHSALGHQPPI 302
Cdd:COG2801   262 LYRRRFESLEEAREAIEEYIEFYNHERPHSSLGYLTPA 299
transpos_IS3 NF033516
IS3 family transposase;
7-302 2.15e-21

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 93.01  E-value: 2.15e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770   7 ARLTRLGRALLVNRVMQQNWTMRQASQAAGVSLRTGYKWLARfrsegldglldRSSRPHRSPKACApEQVEHFAQQRRQR 86
Cdd:NF033516   82 RKLLRPAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKR-----------PPSRRAPDDAELR-ARIREIFEESRGR 149
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  87 LPLWRIAREAGR-----SLATVARYMERIGLSRlaslePPAPVRRYERASPGELLHIDTKRLGR---IRGVGHR----IT 154
Cdd:NF033516  150 YGYRRITALLRRegirvNHKRVYRLMRELGLLA-----RRRRKRRPYTTDSGHVHPVAPNLLNRqftATRPNQVwvtdIT 224
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 155 GDRAQNrnrgiGWDAVHLAIDDFSRvsfaRIL-----DDEGGDQCAEFLRQATAYYASLGVRIdrVMTDNGSGYVSRTFR 229
Cdd:NF033516  225 YIRTAE-----GWLYLAVVLDLFSR----EIVgwsvsTSMSAELVLDALEMAIEWRGKPEGLI--LHSDNGSQYTSKAYR 293
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1988060770 230 AVCVELGIRHIRTRPYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSALGHQPPI 302
Cdd:NF033516  294 EWLKEHGITQSMSRPGNCWDNAVAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPA 366
PHA02517 PHA02517
putative transposase OrfB; Reviewed
217-301 6.76e-12

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 64.89  E-value: 6.76e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 217 TDNGSGYVSRTFRAVCVELGIRHIRTRPYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSAL 296
Cdd:PHA02517  175 SDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATLEWVAWYNNRRLHERL 254

                  ....*
gi 1988060770 297 GHQPP 301
Cdd:PHA02517  255 GYTPP 259
transpos_IS630 NF033545
IS630 family transposase;
11-286 2.16e-11

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 63.43  E-value: 2.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  11 RLGRALLVNRvmqQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRsSRPHRSPKACAPEQVEHFAQ---QRRQRL 87
Cdd:NF033545    1 RRARILLLAA---EGLSITEIAERLGVSRSTVYRWLKRFNEGGLEGLLDK-PRPGRPRKLLSEQQAELLALlleEPPEGA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  88 PLW-------RIAREAGRSL--ATVARYMERIGLS----RLASLE-PPAPVRRY--------ERASPGELLHIDTKR--- 142
Cdd:NF033545   77 GHWtlrelaaLLEEEFGVEYsrSTVRRLLKRLGLSpkkpRPRAPKqDPEFVEKFkevlglyrAPPDPAEVVFIDESGiql 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 143 ---LGRIRGV-GHRITGDRAQNRNRGIGwdaVHLAIDDFSRVSFARILDDEGGDQCAEFLRQATAYYASLGVRIdrVMtD 218
Cdd:NF033545  157 ldtRGRGWAPkGQRRPRVHVYGRRGTLN---LFGALDPLTGKVFVLFTGRINSEDFIEFLEELLAAYPGKKIHL--IL-D 230
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1988060770 219 NGSGYVSRTFRAVCVELG-IRHIRTRPYTPKTNgKAERLVQTCLREWAYARPYTSSAERQAALQPFIDR 286
Cdd:NF033545  231 NASTHKSKKVREWLEEHGrIELHYLPPYSPWLN-PIERVWAVLKRRLLRNRAFRSVDELREAIDAFLNR 298
transpos_IS21 NF033546
IS21 family transposase;
22-300 9.96e-10

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 58.37  E-value: 9.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  22 MQQNWTMRQASQAAGVSLRTGYKWLARFrSEGLDGLLDRssRPHRSPKACAPEQVEH---FAQQRRQRLPLWRIAREAGR 98
Cdd:NF033546    5 FRQGLSIREIARELGISRNTVRKYLRRA-GLDEPPKYER--RPPRPSKLDPFEPYIPdwlEAHLRKPGVTATLLWEELRA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  99 -----SLATVARYMERIglsrLASLEPPAPVRRYERAsPGELLHIDTKRLGRIRGVGHRITgdraqnrnrgigwdaVHLA 173
Cdd:NF033546   82 egypgSYSTVRRYVRRW----RAEQGPAKVFVRLEHA-PGEQAQVDFGEATVVVTGGTGKI---------------LHVF 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 174 IDD--FSRVSFARILDDEGGDQCAEFLRQATAYYAslGVrIDRVMTDNGSGYVS-----------RTFRAVCVELGIRHI 240
Cdd:NF033546  142 VAVlgYSRYTYVEATPSESQEDLLDGHQRAFEFFG--GV-PREIVYDNLKTAVDkrdryeeprlnPRFAAFAAHYGFEPR 218
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1988060770 241 RTRPYTPKTNGKAERLVQTcLREWAYARPY---TSSAERQAALQPFIDRYNWCRPHSALGHQP 300
Cdd:NF033546  219 PCRPYRPQEKGKVERAVGY-VRRWFLRLRGrrfESLAELNAALAEWLAELANQRPHGTTGGSP 280
transpos_ISNCY_2 NF033594
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
18-176 1.04e-05

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 46.71  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  18 VNRVMQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRphRSPKACAPEQVEHFAQQRRQ-----------R 86
Cdd:NF033594    3 IQKVVDGRLTVKEAAELLGLSERQVRRLLKRYREEGAAGLVHGNRG--RPPNNRLPDELRERVLALYReryydfgptlaL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  87 LPLW-----RIAREagrslaTVARYMERIGLSRLASLEPPAP-VRRYERASPGELLHIDtkrlgrirGVGHRITGDRaqn 160
Cdd:NF033594   81 EKLRerhgiSLSRE------TVRRWMIEAGLWSPRKQRRPKVhQPRERRACFGELIQID--------GSPHDWFEGR--- 143
                         170
                  ....*....|....*..
gi 1988060770 161 rnrgiGWD-AVHLAIDD 176
Cdd:NF033594  144 -----GPKcTLLVAIDD 155
 
Name Accession Description Interval E-value
transpos_IS481 NF033577
IS481 family transposase; null
13-305 2.97e-109

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 318.77  E-value: 2.97e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  13 GRALLVNRVMQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRPHRSPKACAPEQVEHFAQQRRQ-RLPLWR 91
Cdd:NF033577    1 GRLELVRLVLEDGWSVREAARRFGISRKTVYKWLKRYRAGGEEGLIDRSRRPHRSPRRTSPETEARILALRRElRLGPRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  92 IAREAGR-----SLATVARYMERIGLSRLASLEPP-APVRRYERASPGELLHIDTKRLGRIRGVGhritgdraqnrnrgi 165
Cdd:NF033577   81 IAYELERqgpgvSRSTVHRILRRHGLSRLRALDRKtGKVKRYERAHPGELWHIDIKKLGRIPDVG--------------- 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 166 gWDAVHLAIDDFSRVSFARILDDEGGDQCAEFLRQAtayYASLGVRIDRVMTDNGSGYVSRT--FRAVCVELGIRHIRTR 243
Cdd:NF033577  146 -RLYLHTAIDDHSRFAYAELYPDETAETAADFLRRA---FAEHGIPIRRVLTDNGSEFRSRAhgFELALAELGIEHRRTR 221
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1988060770 244 PYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSALGHQPPITRI 305
Cdd:NF033577  222 PYHPQTNGKVERFHRTLKDEFAYARPYESLAELQAALDEWLHHYNHHRPHSALGGKTPAERF 283
LZ_Tnp_IS481 pfam13011
leucine-zipper of insertion element IS481; This is the upstream region of the conjoined ORF AB ...
1-85 7.50e-43

leucine-zipper of insertion element IS481; This is the upstream region of the conjoined ORF AB of insertion element 481. The significance of IS481 in the detection of Bordetella pertussis is discussed in. The B portion of the ORF AB carries the transposase activity in family rve, pfam00665.


Pssm-ID: 289759 [Multi-domain]  Cd Length: 85  Bit Score: 142.49  E-value: 7.50e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770   1 MNNHKHARLTRLGRALLVNRVMQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRPHRSPKACAPEQVEHFA 80
Cdd:pfam13011   1 MNNHGHARLTRHGRALLVNRVMEDNRPMAHAAQAAGVSLQCAHKWLARFRAEGLDGLLDRSSRPHRSPKACAPEQEEAFA 80

                  ....*
gi 1988060770  81 QQRRQ 85
Cdd:pfam13011  81 EARAQ 85
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
43-302 5.07e-24

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 99.46  E-value: 5.07e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  43 YKWLARFRSEGLDGLLDRSSRPHRSPKACAPEQVEHFAQQRRQRLPLWRIAREAGR-----SLATVARYMERIGL----- 112
Cdd:COG2801    43 LRLLRRRRARSRRRRRLRRPRSYRADEDAELLERIKEIFAESPRYGYRRITAELRRegiavNRKRVRRLMRELGLqarrr 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 113 ------SRLASLEPPAPVRRYERASPGELLHIDtkrlgrirgvghrITGDRAQNrnrgiGWDAVHLAIDDFSR--VSFaR 184
Cdd:COG2801   123 rkkkytTYSGHGGPIAPNLLFTATAPNQVWVTD-------------ITYIPTAE-----GWLYLAAVIDLFSReiVGW-S 183
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 185 ILDDEGGDQCAEFLRQATAYYASLGVRIdrVMTDNGSGYVSRTFRAVCVELGIRHIRTRPYTPKTNGKAERLVQTCLREW 264
Cdd:COG2801   184 VSDSMDAELVVDALEMAIERRGPPKPLI--LHSDNGSQYTSKAYQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYEL 261
                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1988060770 265 AYARPYTSSAERQAALQPFIDRYNWCRPHSALGHQPPI 302
Cdd:COG2801   262 LYRRRFESLEEAREAIEEYIEFYNHERPHSSLGYLTPA 299
transpos_IS3 NF033516
IS3 family transposase;
7-302 2.15e-21

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 93.01  E-value: 2.15e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770   7 ARLTRLGRALLVNRVMQQNWTMRQASQAAGVSLRTGYKWLARfrsegldglldRSSRPHRSPKACApEQVEHFAQQRRQR 86
Cdd:NF033516   82 RKLLRPAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKR-----------PPSRRAPDDAELR-ARIREIFEESRGR 149
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  87 LPLWRIAREAGR-----SLATVARYMERIGLSRlaslePPAPVRRYERASPGELLHIDTKRLGR---IRGVGHR----IT 154
Cdd:NF033516  150 YGYRRITALLRRegirvNHKRVYRLMRELGLLA-----RRRRKRRPYTTDSGHVHPVAPNLLNRqftATRPNQVwvtdIT 224
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 155 GDRAQNrnrgiGWDAVHLAIDDFSRvsfaRIL-----DDEGGDQCAEFLRQATAYYASLGVRIdrVMTDNGSGYVSRTFR 229
Cdd:NF033516  225 YIRTAE-----GWLYLAVVLDLFSR----EIVgwsvsTSMSAELVLDALEMAIEWRGKPEGLI--LHSDNGSQYTSKAYR 293
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1988060770 230 AVCVELGIRHIRTRPYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSALGHQPPI 302
Cdd:NF033516  294 EWLKEHGITQSMSRPGNCWDNAVAESFFGTLKRECLYRRRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPA 366
rve_3 pfam13683
Integrase core domain;
235-301 1.24e-20

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 83.80  E-value: 1.24e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1988060770 235 LGIRHIRTRPYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSALGHQPP 301
Cdd:pfam13683   1 LGIEISYIAPGKPMQNGLVESFNGTLRDECLNEHLFSSLAEARALLAAWREDYNTERPHSSLGYRTP 67
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
166-247 4.98e-15

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 69.65  E-value: 4.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 166 GWDAVHLAIDDFSRVSFARILDDEG-GDQCAEFLRQATAYYaslGVRIDRVMTDNGSGYVSRTFRAVCVELGIRHIRTRP 244
Cdd:pfam00665  19 GKLYLLVIVDDFSREILAWALSSEMdAELVLDALERAIAFR---GGVPLIIHSDNGSEYTSKAFREFLKDLGIKPSFSRP 95

                  ...
gi 1988060770 245 YTP 247
Cdd:pfam00665  96 GNP 98
PHA02517 PHA02517
putative transposase OrfB; Reviewed
217-301 6.76e-12

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 64.89  E-value: 6.76e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 217 TDNGSGYVSRTFRAVCVELGIRHIRTRPYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSAL 296
Cdd:PHA02517  175 SDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIHRVSWKNREEVELATLEWVAWYNNRRLHERL 254

                  ....*
gi 1988060770 297 GHQPP 301
Cdd:PHA02517  255 GYTPP 259
transpos_IS630 NF033545
IS630 family transposase;
11-286 2.16e-11

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 63.43  E-value: 2.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  11 RLGRALLVNRvmqQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRsSRPHRSPKACAPEQVEHFAQ---QRRQRL 87
Cdd:NF033545    1 RRARILLLAA---EGLSITEIAERLGVSRSTVYRWLKRFNEGGLEGLLDK-PRPGRPRKLLSEQQAELLALlleEPPEGA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  88 PLW-------RIAREAGRSL--ATVARYMERIGLS----RLASLE-PPAPVRRY--------ERASPGELLHIDTKR--- 142
Cdd:NF033545   77 GHWtlrelaaLLEEEFGVEYsrSTVRRLLKRLGLSpkkpRPRAPKqDPEFVEKFkevlglyrAPPDPAEVVFIDESGiql 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 143 ---LGRIRGV-GHRITGDRAQNRNRGIGwdaVHLAIDDFSRVSFARILDDEGGDQCAEFLRQATAYYASLGVRIdrVMtD 218
Cdd:NF033545  157 ldtRGRGWAPkGQRRPRVHVYGRRGTLN---LFGALDPLTGKVFVLFTGRINSEDFIEFLEELLAAYPGKKIHL--IL-D 230
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1988060770 219 NGSGYVSRTFRAVCVELG-IRHIRTRPYTPKTNgKAERLVQTCLREWAYARPYTSSAERQAALQPFIDR 286
Cdd:NF033545  231 NASTHKSKKVREWLEEHGrIELHYLPPYSPWLN-PIERVWAVLKRRLLRNRAFRSVDELREAIDAFLNR 298
transpos_IS21 NF033546
IS21 family transposase;
22-300 9.96e-10

IS21 family transposase;


Pssm-ID: 468077 [Multi-domain]  Cd Length: 296  Bit Score: 58.37  E-value: 9.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  22 MQQNWTMRQASQAAGVSLRTGYKWLARFrSEGLDGLLDRssRPHRSPKACAPEQVEH---FAQQRRQRLPLWRIAREAGR 98
Cdd:NF033546    5 FRQGLSIREIARELGISRNTVRKYLRRA-GLDEPPKYER--RPPRPSKLDPFEPYIPdwlEAHLRKPGVTATLLWEELRA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  99 -----SLATVARYMERIglsrLASLEPPAPVRRYERAsPGELLHIDTKRLGRIRGVGHRITgdraqnrnrgigwdaVHLA 173
Cdd:NF033546   82 egypgSYSTVRRYVRRW----RAEQGPAKVFVRLEHA-PGEQAQVDFGEATVVVTGGTGKI---------------LHVF 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 174 IDD--FSRVSFARILDDEGGDQCAEFLRQATAYYAslGVrIDRVMTDNGSGYVS-----------RTFRAVCVELGIRHI 240
Cdd:NF033546  142 VAVlgYSRYTYVEATPSESQEDLLDGHQRAFEFFG--GV-PREIVYDNLKTAVDkrdryeeprlnPRFAAFAAHYGFEPR 218
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1988060770 241 RTRPYTPKTNGKAERLVQTcLREWAYARPY---TSSAERQAALQPFIDRYNWCRPHSALGHQP 300
Cdd:NF033546  219 PCRPYRPQEKGKVERAVGY-VRRWFLRLRGrrfESLAELNAALAEWLAELANQRPHGTTGGSP 280
Csa3 COG3415
CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein ...
1-304 1.34e-09

CRISPR-associated protein Csa3, CARF domain [Defense mechanisms]; CRISPR-associated protein Csa3, CARF domain is part of the Pathway/BioSystem: CRISPR-Cas system


Pssm-ID: 442641 [Multi-domain]  Cd Length: 325  Bit Score: 58.32  E-value: 1.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770   1 MNNHKHARLTRlgRALLVNRVmQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRphRSPKACAPEQVEHFA 80
Cdd:COG3415    17 LRKTKDAREAR--RLRAVLLL-AEGLSVREIAERLGVSRSTVYRWLKRYREGGLAGLKDRPRG--GRPSKLSDEQRERLL 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  81 QQRRQRLP----LW-------RIAREAGR--SLATVARYMERIGLSRL-ASLEPPAPVRRYERASPGELLHIDTKRLGRI 146
Cdd:COG3415    92 ELLREKSPdqgsRWtlaelaeLLEEEFGVevSPSTVRRLLKRLGLSYKkPRPRAPKQDPEAVEKFKKELEALLAKPAKAE 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 147 RGVGHRITGDRAQNRNRGIGWDAVHLAIDDFSRVSFARilddeggdQCAEFLRQATAYYASLGVRIDRVMTDNGSGYVSR 226
Cdd:COG3415   172 VAGVDEGDEIGALRRAAGGRLLAPGGRVRRTGASVRRG--------RALLFLALGLALGLRIGLTIDALLAGALLLFLRL 243
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1988060770 227 TFRAVCVELGIRHIRTRPYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSALGHQPPITR 304
Cdd:COG3415   244 LAERALALLLLLLLLLLLSPSKAVARAAKLLKLELLRLLFLPPSASLLLALEALLRELRERNLLRLAHASLLLLFAAA 321
PRK14702 PRK14702
insertion element IS2 transposase InsD; Provisional
216-301 3.62e-06

insertion element IS2 transposase InsD; Provisional


Pssm-ID: 237792 [Multi-domain]  Cd Length: 262  Bit Score: 47.42  E-value: 3.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 216 MTDNGSGYVSRTFRAVCVELGIRHIRTRPYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSA 295
Cdd:PRK14702  157 LTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSA 236

                  ....*.
gi 1988060770 296 LGHQPP 301
Cdd:PRK14702  237 LGYRSP 242
PRK09409 PRK09409
IS2 transposase TnpB; Reviewed
216-301 4.10e-06

IS2 transposase TnpB; Reviewed


Pssm-ID: 181829 [Multi-domain]  Cd Length: 301  Bit Score: 47.79  E-value: 4.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770 216 MTDNGSGYVSRTFRAVCVELGIRHIRTRPYTPKTNGKAERLVQTCLREWAYARPYTSSAERQAALQPFIDRYNWCRPHSA 295
Cdd:PRK09409  196 LTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSA 275

                  ....*.
gi 1988060770 296 LGHQPP 301
Cdd:PRK09409  276 LGYRSP 281
transpos_ISNCY_2 NF033594
ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes ...
18-176 1.04e-05

ISNCY family transposase; The ISNCY insertion sequence family, as defined by ISFinder, encodes several apparently unrelated families of transposases. Members of this family resemble the transposases of ISNCY family elements such as IS1202, ISTde1, ISKpn21, and ISCARN1.


Pssm-ID: 468103 [Multi-domain]  Cd Length: 367  Bit Score: 46.71  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  18 VNRVMQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRphRSPKACAPEQVEHFAQQRRQ-----------R 86
Cdd:NF033594    3 IQKVVDGRLTVKEAAELLGLSERQVRRLLKRYREEGAAGLVHGNRG--RPPNNRLPDELRERVLALYReryydfgptlaL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1988060770  87 LPLW-----RIAREagrslaTVARYMERIGLSRLASLEPPAP-VRRYERASPGELLHIDtkrlgrirGVGHRITGDRaqn 160
Cdd:NF033594   81 EKLRerhgiSLSRE------TVRRWMIEAGLWSPRKQRRPKVhQPRERRACFGELIQID--------GSPHDWFEGR--- 143
                         170
                  ....*....|....*..
gi 1988060770 161 rnrgiGWD-AVHLAIDD 176
Cdd:NF033594  144 -----GPKcTLLVAIDD 155
HTH_28 pfam13518
Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is ...
14-65 1.95e-05

Helix-turn-helix domain; This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.


Pssm-ID: 463908 [Multi-domain]  Cd Length: 52  Bit Score: 41.42  E-value: 1.95e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1988060770  14 RALLVNRVMQQNwTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRPH 65
Cdd:pfam13518   2 RLKIVLLALEGE-SIKEAARLFGISRSTVYRWIRRYREGGLEGLLPRRRRPK 52
HTH_32 pfam13565
Homeodomain-like domain;
41-107 5.33e-05

Homeodomain-like domain;


Pssm-ID: 463923 [Multi-domain]  Cd Length: 73  Bit Score: 40.74  E-value: 5.33e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1988060770  41 TGYKWLARFRSEGLDGLLDRSSRPHrsPKACAPEQVEHFAQQRRQ--RLPLWRIAREAGR------SLATVARYM 107
Cdd:pfam13565   1 TVYRWRKRYNEEGLEGLEDRPRRGR--PRKLTDEQEARLLALLCEepRWSPRLLAERLEEefgvkvSRSTVRRIL 73
HTH_29 pfam13551
Winged helix-turn helix; This helix-turn-helix domain is often found in transferases and is ...
14-75 9.55e-05

Winged helix-turn helix; This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.


Pssm-ID: 433301 [Multi-domain]  Cd Length: 64  Bit Score: 39.66  E-value: 9.55e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1988060770  14 RALLVNRVMQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLLDRSSRPHRSPKACAPEQ 75
Cdd:pfam13551   1 RALALLLLAEGVSTVSQAARLLGLSRRTVYRWLKRFNEGGLAALLDRPRSGRPRNNRLDEEQ 62
HTH_23 pfam13384
Homeodomain-like domain;
14-58 1.61e-04

Homeodomain-like domain;


Pssm-ID: 433164 [Multi-domain]  Cd Length: 50  Bit Score: 38.79  E-value: 1.61e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1988060770  14 RALLVNRVmQQNWTMRQASQAAGVSLRTGYKWLARFRSEGLDGLL 58
Cdd:pfam13384   7 RARALLLL-AEGLSVKEIAELLGVSRRTVYRWLKRYNEEGLEGLL 50
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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