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Conserved domains on  [gi|2022145540|gb|QTO02445|]
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chromosomal replication initiator protein DnaA [Lactiplantibacillus plantarum]

Protein Classification

chromosomal replication initiator protein DnaA( domain architecture ID 11489097)

chromosomal replication initiator protein DnaA plays a key role in the initiation and regulation of chromosomal replication

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
8-453 0e+00

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 655.75  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540   8 WNLIKFSMEQDLSKITFQTFVEPAKPLQLDKAQMTIEVPTQLHRDYWEKNLAAKFTDIAMQATNEQIRPVMITEEERQQL 87
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLLSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540  88 TRDKDSQVTTGNVAGQQPTTAttptfmreTKLNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLGKTH 167
Cdd:TIGR00362  81 EPNSKKPEPAPPEAPAPPSSA--------SGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTH 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 168 LMHAIGNKLLETDPTSNIKYVTSESFTNELINAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYED 247
Cdd:TIGR00362 153 LLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHTFNALHEN 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 248 DKQIVLTSDRLPNEIPQLQDRLVSRFKWGLSVDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGAL 327
Cdd:TIGR00362 233 NKQIVLTSDRPPKELPGLEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSNVRELEGAL 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 328 ARVQAYSRLNNSPITTSLVADALKSLhLSSKLSEVSIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTE 407
Cdd:TIGR00362 313 NRLLAYASLTGKPITLELAKEALKDL-LRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYLAKELTD 391
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2022145540 408 SSLPRIGNEFGGKDHTTVIHAHDKITKALKTDAELQKAVGDLTGQL 453
Cdd:TIGR00362 392 LSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEELKRKL 437
 
Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
8-453 0e+00

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 655.75  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540   8 WNLIKFSMEQDLSKITFQTFVEPAKPLQLDKAQMTIEVPTQLHRDYWEKNLAAKFTDIAMQATNEQIRPVMITEEERQQL 87
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLLSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540  88 TRDKDSQVTTGNVAGQQPTTAttptfmreTKLNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLGKTH 167
Cdd:TIGR00362  81 EPNSKKPEPAPPEAPAPPSSA--------SGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTH 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 168 LMHAIGNKLLETDPTSNIKYVTSESFTNELINAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYED 247
Cdd:TIGR00362 153 LLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHTFNALHEN 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 248 DKQIVLTSDRLPNEIPQLQDRLVSRFKWGLSVDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGAL 327
Cdd:TIGR00362 233 NKQIVLTSDRPPKELPGLEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSNVRELEGAL 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 328 ARVQAYSRLNNSPITTSLVADALKSLhLSSKLSEVSIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTE 407
Cdd:TIGR00362 313 NRLLAYASLTGKPITLELAKEALKDL-LRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYLAKELTD 391
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2022145540 408 SSLPRIGNEFGGKDHTTVIHAHDKITKALKTDAELQKAVGDLTGQL 453
Cdd:TIGR00362 392 LSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEELKRKL 437
dnaA PRK00149
chromosomal replication initiator protein DnaA;
5-455 0e+00

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 642.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540   5 NDLWNLIKFSMEQDLSKITFQTFVEPAKPLQLDKAQMTIEVPTQLHRDYWEKNLAAKFTDIAmqatneqirpvmiteeer 84
Cdd:PRK00149    3 QSLWEKVLERLKDELSEQEYETWIKPLKALSLEDNTLTLYVPNRFVKDWIEKNYLDLIEEAL------------------ 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540  85 qqltrdkdsqvttgnvagqqpttattptfmretKLNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLG 164
Cdd:PRK00149   65 ---------------------------------QLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLG 111
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 165 KTHLMHAIGNKLLETDPTSNIKYVTSESFTNELINAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNAL 244
Cdd:PRK00149  112 KTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFVNALRNNTMEEFKEKYRSVDVLLIDDIQFLAGKERTQEEFFHTFNAL 191
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 245 YEDDKQIVLTSDRLPNEIPQLQDRLVSRFKWGLSVDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELE 324
Cdd:PRK00149  192 HEAGKQIVLTSDRPPKELPGLEERLRSRFEWGLTVDIEPPDLETRIAILKKKAEEEGIDLPDEVLEFIAKNITSNVRELE 271
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 325 GALARVQAYSRLNNSPITTSLVADALKSLhLSSKLSEVSIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRE 404
Cdd:PRK00149  272 GALNRLIAYASLTGKPITLELAKEALKDL-LAAQKKKITIENIQKVVAEYYNIKVSDLKSKSRTRNIARPRQIAMYLAKE 350
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2022145540 405 LTESSLPRIGNEFGGKDHTTVIHAHDKITKALKTDAELQKAVGDLTGQLKS 455
Cdd:PRK00149  351 LTDLSLPEIGRAFGGRDHTTVLHAVRKIEKLLEEDPELKEDVEELKRKLKS 401
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
119-422 0e+00

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 521.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 119 LNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLGKTHLMHAIGNKLLETDPTSNIKYVTSESFTNELI 198
Cdd:COG0593     1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 199 NAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYEDDKQIVLTSDRLPNEIPQLQDRLVSRFKWGLS 278
Cdd:COG0593    81 NAIRNNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 279 VDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGALARVQAYSRLNNSPITTSLVADALKSLhLSSK 358
Cdd:COG0593   161 VDIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDL-LRAQ 239
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2022145540 359 LSEVSIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTESSLPRIGNEFGGKDH 422
Cdd:COG0593   240 KKEITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
Bac_DnaA pfam00308
Bacterial dnaA protein;
119-337 1.54e-120

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 350.47  E-value: 1.54e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 119 LNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLGKTHLMHAIGNKLLETDPTSNIKYVTSESFTNELI 198
Cdd:pfam00308   1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 199 NAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYEDDKQIVLTSDRLPNEIPQLQDRLVSRFKWGLS 278
Cdd:pfam00308  81 DAIRDNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWGLV 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2022145540 279 VDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGALARVQAYSRLN 337
Cdd:pfam00308 161 TDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSLN 219
Bac_DnaA_C cd06571
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ...
367-453 6.27e-39

C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.


Pssm-ID: 119330 [Multi-domain]  Cd Length: 90  Bit Score: 135.72  E-value: 6.27e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 367 IQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTESSLPRIGNEFGGKDHTTVIHAHDKITKALKTDAELQKAV 446
Cdd:cd06571     4 IIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELKEDV 83

                  ....*..
gi 2022145540 447 GDLTGQL 453
Cdd:cd06571    84 EELEKKL 90
Bac_DnaA_C smart00760
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
363-431 1.45e-33

Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.


Pssm-ID: 197863 [Multi-domain]  Cd Length: 69  Bit Score: 120.69  E-value: 1.45e-33
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2022145540  363 SIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTESSLPRIGNEFGGKDHTTVIHAHDK 431
Cdd:smart00760   1 TIEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
157-255 1.43e-04

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 43.23  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 157 FYGGVGLGKTHLMHAIGNKLLEtdptSNIK--YVTsesfTNELINAIQTKKQEA-FREEYR---NVDLLLVDDIQF--FA 228
Cdd:NF038214   95 LLGPPGTGKTHLAIALGYAACR----QGYRvrFTT----AADLVEQLAQARADGrLGRLLRrlaRYDLLIIDELGYlpFS 166
                          90       100
                  ....*....|....*....|....*..
gi 2022145540 229 NKEAtqEEFFHTFNALYEdDKQIVLTS 255
Cdd:NF038214  167 REGA--NLLFELIADRYE-RGSTIITS 190
 
Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
8-453 0e+00

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 655.75  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540   8 WNLIKFSMEQDLSKITFQTFVEPAKPLQLDKAQMTIEVPTQLHRDYWEKNLAAKFTDIAMQATNEQIRPVMITEEERQQL 87
Cdd:TIGR00362   1 WNRILERLEKELSEQEYNTWFKPLKLLSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEEL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540  88 TRDKDSQVTTGNVAGQQPTTAttptfmreTKLNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLGKTH 167
Cdd:TIGR00362  81 EPNSKKPEPAPPEAPAPPSSA--------SGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTH 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 168 LMHAIGNKLLETDPTSNIKYVTSESFTNELINAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYED 247
Cdd:TIGR00362 153 LLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHTFNALHEN 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 248 DKQIVLTSDRLPNEIPQLQDRLVSRFKWGLSVDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGAL 327
Cdd:TIGR00362 233 NKQIVLTSDRPPKELPGLEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSNVRELEGAL 312
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 328 ARVQAYSRLNNSPITTSLVADALKSLhLSSKLSEVSIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTE 407
Cdd:TIGR00362 313 NRLLAYASLTGKPITLELAKEALKDL-LRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYLAKELTD 391
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2022145540 408 SSLPRIGNEFGGKDHTTVIHAHDKITKALKTDAELQKAVGDLTGQL 453
Cdd:TIGR00362 392 LSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEELKRKL 437
dnaA PRK00149
chromosomal replication initiator protein DnaA;
5-455 0e+00

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 642.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540   5 NDLWNLIKFSMEQDLSKITFQTFVEPAKPLQLDKAQMTIEVPTQLHRDYWEKNLAAKFTDIAmqatneqirpvmiteeer 84
Cdd:PRK00149    3 QSLWEKVLERLKDELSEQEYETWIKPLKALSLEDNTLTLYVPNRFVKDWIEKNYLDLIEEAL------------------ 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540  85 qqltrdkdsqvttgnvagqqpttattptfmretKLNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLG 164
Cdd:PRK00149   65 ---------------------------------QLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLG 111
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 165 KTHLMHAIGNKLLETDPTSNIKYVTSESFTNELINAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNAL 244
Cdd:PRK00149  112 KTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFVNALRNNTMEEFKEKYRSVDVLLIDDIQFLAGKERTQEEFFHTFNAL 191
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 245 YEDDKQIVLTSDRLPNEIPQLQDRLVSRFKWGLSVDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELE 324
Cdd:PRK00149  192 HEAGKQIVLTSDRPPKELPGLEERLRSRFEWGLTVDIEPPDLETRIAILKKKAEEEGIDLPDEVLEFIAKNITSNVRELE 271
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 325 GALARVQAYSRLNNSPITTSLVADALKSLhLSSKLSEVSIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRE 404
Cdd:PRK00149  272 GALNRLIAYASLTGKPITLELAKEALKDL-LAAQKKKITIENIQKVVAEYYNIKVSDLKSKSRTRNIARPRQIAMYLAKE 350
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2022145540 405 LTESSLPRIGNEFGGKDHTTVIHAHDKITKALKTDAELQKAVGDLTGQLKS 455
Cdd:PRK00149  351 LTDLSLPEIGRAFGGRDHTTVLHAVRKIEKLLEEDPELKEDVEELKRKLKS 401
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
119-422 0e+00

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 521.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 119 LNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLGKTHLMHAIGNKLLETDPTSNIKYVTSESFTNELI 198
Cdd:COG0593     1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 199 NAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYEDDKQIVLTSDRLPNEIPQLQDRLVSRFKWGLS 278
Cdd:COG0593    81 NAIRNNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 279 VDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGALARVQAYSRLNNSPITTSLVADALKSLhLSSK 358
Cdd:COG0593   161 VDIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDL-LRAQ 239
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2022145540 359 LSEVSIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTESSLPRIGNEFGGKDH 422
Cdd:COG0593   240 KKEITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
dnaA PRK14086
chromosomal replication initiator protein DnaA;
118-454 4.95e-145

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 427.70  E-value: 4.95e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 118 KLNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLGKTHLMHAIGNKLLETDPTSNIKYVTSESFTNEL 197
Cdd:PRK14086  280 RLNPKYTFDTFVIGASNRFAHAAAVAVAEAPAKAYNPLFIYGESGLGKTHLLHAIGHYARRLYPGTRVRYVSSEEFTNEF 359
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 198 INAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYEDDKQIVLTSDRLPNEIPQLQDRLVSRFKWGL 277
Cdd:PRK14086  360 INSIRDGKGDSFRRRYREMDILLVDDIQFLEDKESTQEEFFHTFNTLHNANKQIVLSSDRPPKQLVTLEDRLRNRFEWGL 439
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 278 SVDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGALARVQAYSRLNNSPITTSLVADALKSLHLSS 357
Cdd:PRK14086  440 ITDVQPPELETRIAILRKKAVQEQLNAPPEVLEFIASRISRNIRELEGALIRVTAFASLNRQPVDLGLTEIVLRDLIPED 519
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 358 KLSEVSIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTESSLPRIGNEFgGKDHTTVIHAHDKITKALK 437
Cdd:PRK14086  520 SAPEITAAAIMAATADYFGLTVEDLCGTSRSRVLVTARQIAMYLCRELTDLSLPKIGQQF-GRDHTTVMHADRKIRALMA 598
                         330
                  ....*....|....*..
gi 2022145540 438 TDAELQKAVGDLTGQLK 454
Cdd:PRK14086  599 ERRSIYNQVTELTNRIK 615
Bac_DnaA pfam00308
Bacterial dnaA protein;
119-337 1.54e-120

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 350.47  E-value: 1.54e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 119 LNPKYTFDTFVIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLGKTHLMHAIGNKLLETDPTSNIKYVTSESFTNELI 198
Cdd:pfam00308   1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 199 NAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYEDDKQIVLTSDRLPNEIPQLQDRLVSRFKWGLS 278
Cdd:pfam00308  81 DAIRDNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWGLV 160
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2022145540 279 VDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGALARVQAYSRLN 337
Cdd:pfam00308 161 TDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSLN 219
PRK12422 PRK12422
chromosomal replication initiator protein DnaA;
114-455 3.25e-71

chromosomal replication initiator protein DnaA;


Pssm-ID: 183521 [Multi-domain]  Cd Length: 445  Bit Score: 232.03  E-value: 3.25e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 114 MRETKLNPKYTFDTFVIGKGNQMAHAAALVVSEEP----GTMYNPLFFYGGVGLGKTHLMHAIGNKLLETDptSNIKYVT 189
Cdd:PRK12422   99 MKYGELDPLMTFANFLVTPENDLPHRILQEFTKVSeqgkGFPFNPIYLFGPEGSGKTHLMQAAVHALRESG--GKILYVR 176
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 190 SESFTNELINAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYEDDKQIVLTSDRLPNEIPQLQDRL 269
Cdd:PRK12422  177 SELFTEHLVSAIRSGEMQRFRQFYRNVDALFIEDIEVFSGKGATQEEFFHTFNSLHTEGKLIVISSTCAPQDLKAMEERL 256
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 270 VSRFKWGLSVDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGA---LARVQAYSRLNNSPITTSLV 346
Cdd:PRK12422  257 ISRFEWGIAIPLHPLTKEGLRSFLERKAEALSIRIEETALDFLIEALSSNVKSLLHAltlLAKRVAYKKLSHQLLYVDDI 336
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 347 ADALKSLHLSSKLSEVSIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTESSLPRIGNEFgGKDHTTVI 426
Cdd:PRK12422  337 KALLHDVLEAAESVRLTPSKIIRAVAQYYGVSPESILGRSQSREYVLPRQVAMYLCRQKLSLSYVKIGDVF-SRDHSTVI 415
                         330       340       350
                  ....*....|....*....|....*....|
gi 2022145540 427 HAHDKITKALKTDA-ELQKAVGDLTGQLKS 455
Cdd:PRK12422  416 SSIRAISQKLEEDDrDISMAIQEITKRLSS 445
Bac_DnaA_C cd06571
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ...
367-453 6.27e-39

C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.


Pssm-ID: 119330 [Multi-domain]  Cd Length: 90  Bit Score: 135.72  E-value: 6.27e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 367 IQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTESSLPRIGNEFGGKDHTTVIHAHDKITKALKTDAELQKAV 446
Cdd:cd06571     4 IIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELKEDV 83

                  ....*..
gi 2022145540 447 GDLTGQL 453
Cdd:cd06571    84 EELEKKL 90
Bac_DnaA_C pfam08299
Bacterial dnaA protein helix-turn-helix;
367-432 3.88e-37

Bacterial dnaA protein helix-turn-helix;


Pssm-ID: 462419 [Multi-domain]  Cd Length: 69  Bit Score: 130.21  E-value: 3.88e-37
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2022145540 367 IQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTESSLPRIGNEFGGKDHTTVIHAHDKI 432
Cdd:pfam08299   4 IIEAVAEYFGISPEDLKSKSRKREIALARQIAMYLARELTDLSLPEIGRAFGGRDHSTVIHACKKI 69
Bac_DnaA_C smart00760
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
363-431 1.45e-33

Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.


Pssm-ID: 197863 [Multi-domain]  Cd Length: 69  Bit Score: 120.69  E-value: 1.45e-33
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2022145540  363 SIPVIQEKVAKYFHVTMADLKGKKRNKQIVIPRQIAMYLSRELTESSLPRIGNEFGGKDHTTVIHAHDK 431
Cdd:smart00760   1 TIEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
124-351 1.13e-25

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 104.19  E-value: 1.13e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 124 TFDTFVIGkGNQ--MAHAAALVVSEEPgtmyNPLFFYGGVGLGKTHLMHAIGNKLLETDptSNIKYVTSESFTNELINAI 201
Cdd:TIGR03420  13 TFDNFYAG-GNAelLAALRQLAAGKGD----RFLYLWGESGSGKSHLLQAACAAAEERG--KSAIYLPLAELAQADPEVL 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 202 QTkkQEAFreeyrnvDLLLVDDIQFFANKEATQEEFFHTFNALYEDDKQIVLTSDRLPNEIP-QLQDrLVSRFKWGLSVD 280
Cdd:TIGR03420  86 EG--LEQA-------DLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPlRLPD-LRTRLAWGLVFQ 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2022145540 281 ITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGALARVQAYSRLNNSPITTSLVADALK 351
Cdd:TIGR03420 156 LPPLSDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
132-277 2.75e-18

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 81.42  E-value: 2.75e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 132 KGNQMAHAAALVVSEEPGtmYNPLFFYGGVGLGKTHLMHAIGNKLLETDPtsNIKYVTSESFTNELINAIQ----TKKQE 207
Cdd:cd00009     1 VGQEEAIEALREALELPP--PKNLLLYGPPGTGKTTLARAIANELFRPGA--PFLYLNASDLLEGLVVAELfghfLVRLL 76
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2022145540 208 AFREEYRNVDLLLVDDIQFFAN-KEATQEEFFHTFN---ALYEDDKQIVLTSDRLPN-EIPQLQDRLVSRFKWGL 277
Cdd:cd00009    77 FELAEKAKPGVLFIDEIDSLSRgAQNALLRVLETLNdlrIDRENVRVIGATNRPLLGdLDRALYDRLDIRIVIPL 151
PRK08084 PRK08084
DnaA inactivator Hda;
124-351 2.39e-15

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 75.10  E-value: 2.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 124 TFDTFVIGKGNQMAHAAALVVSEEPGTMynpLFFYGGVGLGKTHLMHAIGNKLLETDPTSNikYV---TSESFTNELINA 200
Cdd:PRK08084   20 TFASFYPGDNDSLLAALQNALRQEHSGY---IYLWSREGAGRSHLLHAACAELSQRGRAVG--YVpldKRAWFVPEVLEG 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 201 IQtkkqeafreeyrNVDLLLVDDIQFFANKEATQEEFFHTFNALYEDDK-QIVLTSDRLPNEIPQLQDRLVSRFKWGLSV 279
Cdd:PRK08084   95 ME------------QLSLVCIDNIECIAGDELWEMAIFDLYNRILESGRtRLLITGDRPPRQLNLGLPDLASRLDWGQIY 162
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2022145540 280 DITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGALARVQAYSRLNNSPITTSLVADALK 351
Cdd:PRK08084  163 KLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILK 234
PRK08116 PRK08116
hypothetical protein; Validated
122-272 1.19e-13

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 70.82  E-value: 1.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 122 KYTFDTFVIGKGNQMAHAAALVVSEEPGTMYN---PLFFYGGVGLGKTHLMHAIGNKLLEtdptsniKYVTSeSFTN--E 196
Cdd:PRK08116   81 NSTFENFLFDKGSEKAYKIARKYVKKFEEMKKenvGLLLWGSVGTGKTYLAACIANELIE-------KGVPV-IFVNfpQ 152
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 197 LINAIQTKKQEAFREEY-------RNVDLLLVDDIQFFANKEATQEEFFHTFNALYEDDKQIVLTSDRLPNEIP-QLQDR 268
Cdd:PRK08116  153 LLNRIKSTYKSSGKEDEneiirslVNADLLILDDLGAERDTEWAREKVYNIIDSRYRKGLPTIVTTNLSLEELKnQYGKR 232

                  ....
gi 2022145540 269 LVSR 272
Cdd:PRK08116  233 IYDR 236
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
155-255 1.40e-11

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 64.42  E-value: 1.40e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 155 LFFYGGVGLGKTHLMHAIGNKLLETDPTSniKYVTSESFTNELINAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQ 234
Cdd:COG1484   102 LILLGPPGTGKTHLAIALGHEACRAGYRV--RFTTAPDLVNELKEARADGRLERLLKRLAKVDLLILDELGYLPLDAEGA 179
                          90       100
                  ....*....|....*....|.
gi 2022145540 235 EEFFHTFNALYEdDKQIVLTS 255
Cdd:COG1484   180 ELLFELISDRYE-RRSTIITS 199
PRK08903 PRK08903
DnaA regulatory inactivator Hda; Validated
124-354 1.31e-10

DnaA regulatory inactivator Hda; Validated


Pssm-ID: 236347 [Multi-domain]  Cd Length: 227  Bit Score: 61.15  E-value: 1.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 124 TFDTFVIGkGNQMAHAA--ALVVSEEPGTmynplFFY--GGVGLGKTHLMHAIGNKLLETDptSNIKYvtsesftnelIN 199
Cdd:PRK08903   16 TFDNFVAG-ENAELVARlrELAAGPVADR-----FFYlwGEAGSGRSHLLQALVADASYGG--RNARY----------LD 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 200 AIQTKKQEAFREEyrnVDLLLVDDIQffANKEATQEEFFHTFNALYEDDKQIVLTS-DRLPNEIPqLQDRLVSRFKWGLS 278
Cdd:PRK08903   78 AASPLLAFDFDPE---AELYAVDDVE--RLDDAQQIALFNLFNRVRAHGQGALLVAgPAAPLALP-LREDLRTRLGWGLV 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2022145540 279 VDITPPDLETRIAILRNKADLEGIEIPDDTLSYIAGQIDSNVRELEGALARVQAYSRLNNSPITTSLVADALKSLH 354
Cdd:PRK08903  152 YELKPLSDADKIAALKAAAAERGLQLADEVPDYLLTHFRRDMPSLMALLDALDRYSLEQKRPVTLPLLREMLAQPE 227
PRK06835 PRK06835
DNA replication protein DnaC; Validated
155-274 1.74e-08

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 56.06  E-value: 1.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 155 LFFYGGVGLGKTHLMHAIGNKLLETDPTsnIKYVTSESFTnELINAIQTKKQEAFREEY---RNVDLLLVDDIQFFANKE 231
Cdd:PRK06835  186 LLFYGNTGTGKTFLSNCIAKELLDRGKS--VIYRTADELI-EILREIRFNNDKELEEVYdllINCDLLIIDDLGTEKITE 262
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2022145540 232 ATQEEFFHTFNALYEDDKQIVLTSDRLPNEIPQLQD-----RLVSRFK 274
Cdd:PRK06835  263 FSKSELFNLINKRLLRQKKMIISTNLSLEELLKTYSerissRLLGNFT 310
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
153-263 2.73e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 50.06  E-value: 2.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540  153 NPLFFYGGVGLGKTHLMHAIGNKLLEtdPTSNIKYVTSESFTNELINAI-------------QTKKQEAFRE--EYRNVD 217
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGP--PGGGVIYIDGEDILEEVLDQLlliivggkkasgsGELRLRLALAlaRKLKPD 80
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2022145540  218 LLLVDDIQFFANKEATQEEFFH-----TFNALYEDDKQIVLTSDRLPNEIP 263
Cdd:smart00382  81 VLILDEITSLLDAEQEALLLLLeelrlLLLLKSEKNLTVILTTNDEKDLGP 131
PRK06921 PRK06921
hypothetical protein; Provisional
149-272 4.06e-06

hypothetical protein; Provisional


Pssm-ID: 180750 [Multi-domain]  Cd Length: 266  Bit Score: 48.24  E-value: 4.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 149 GTMYNPLFFYGGVGLGKTHLMHAIGNKLLETDPTSNIKYVTSESFTN--ELINAIQTKkqeafREEYRNVDLLLVDDIQF 226
Cdd:PRK06921  114 ESRKNSIALLGQPGSGKTHLLTAAANELMRKKGVPVLYFPFVEGFGDlkDDFDLLEAK-----LNRMKKVEVLFIDDLFK 188
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2022145540 227 FANKE--ATQ---EEFFHTFNALYEDDKQIVLTSDRLPNEIPQLQDRLVSR 272
Cdd:PRK06921  189 PVNGKprATEwqiEQMYSVLNYRYLNHKPILISSELTIDELLDIDEALGSR 239
PRK12377 PRK12377
putative replication protein; Provisional
119-224 1.32e-05

putative replication protein; Provisional


Pssm-ID: 183482 [Multi-domain]  Cd Length: 248  Bit Score: 46.37  E-value: 1.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 119 LNPKYTFDTF-VIGKGNQMAHAAALVVSEEPGTMYNPLFFYGGVGLGKTHLMHAIGNKLLETDPT------SNIKYVTSE 191
Cdd:PRK12377   67 LHRKCSFANYqVQNDGQRYALSQAKSIADELMTGCTNFVFSGKPGTGKNHLAAAIGNRLLAKGRSvivvtvPDVMSRLHE 146
                          90       100       110
                  ....*....|....*....|....*....|...
gi 2022145540 192 SFTNelinaiqTKKQEAFREEYRNVDLLLVDDI 224
Cdd:PRK12377  147 SYDN-------GQSGEKFLQELCKVDLLVLDEI 172
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
157-255 1.43e-04

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 43.23  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 157 FYGGVGLGKTHLMHAIGNKLLEtdptSNIK--YVTsesfTNELINAIQTKKQEA-FREEYR---NVDLLLVDDIQF--FA 228
Cdd:NF038214   95 LLGPPGTGKTHLAIALGYAACR----QGYRvrFTT----AADLVEQLAQARADGrLGRLLRrlaRYDLLIIDELGYlpFS 166
                          90       100
                  ....*....|....*....|....*..
gi 2022145540 229 NKEAtqEEFFHTFNALYEdDKQIVLTS 255
Cdd:NF038214  167 REGA--NLLFELIADRYE-RGSTIITS 190
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
5-68 2.01e-04

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 39.57  E-value: 2.01e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2022145540   5 NDLWNLIKFSMEQDLSKITFQTFVEPAKPLQLDKA-QMTIEVPTQLHRDYWEKNLAAKFTDIAMQ 68
Cdd:pfam11638   1 EELWERVLERLRKEVGEQTFNTWIKPLTLVDLDDGgSLTLSVPNRFVRDWVEEHYLDRILELWQE 65
PRK08939 PRK08939
primosomal protein DnaI; Reviewed
155-224 2.05e-04

primosomal protein DnaI; Reviewed


Pssm-ID: 236353 [Multi-domain]  Cd Length: 306  Bit Score: 43.32  E-value: 2.05e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 155 LFFYGGVGLGKTHLMHAIGNKLLETDPTSNIKYVTseSFTNELINAIQTKKQEAFREEYRNVDLLLVDDI 224
Cdd:PRK08939  159 LYLYGDFGVGKSYLLAAIANELAKKGVSSTLLHFP--EFIRELKNSISDGSVKEKIDAVKEAPVLMLDDI 226
PRK08181 PRK08181
transposase; Validated
116-257 2.28e-04

transposase; Validated


Pssm-ID: 136670 [Multi-domain]  Cd Length: 269  Bit Score: 42.99  E-value: 2.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 116 ETKLNPKYTFDTF------VIGKGNQMAHAAALVVSEEPGTmynpLFFYGGVGLGKTHLMHAIGNKLLETDptsnikYVT 189
Cdd:PRK08181   68 EAHLPPGKTLDSFdfeavpMVSKAQVMAIAAGDSWLAKGAN----LLLFGPPGGGKSHLAAAIGLALIENG------WRV 137
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2022145540 190 SESFTNELINAIQTKKQEAFRE----EYRNVDLLLVDDIQFFANKEATQEEFFHTFNALYEdDKQIVLTSDR 257
Cdd:PRK08181  138 LFTRTTDLVQKLQVARRELQLEsaiaKLDKFDLLILDDLAYVTKDQAETSVLFELISARYE-RRSILITANQ 208
PRK06030 PRK06030
hypothetical protein; Provisional
371-449 3.04e-04

hypothetical protein; Provisional


Pssm-ID: 180356  Cd Length: 124  Bit Score: 40.53  E-value: 3.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 371 VAKYFHVTMADLKGKKRNKQIVI-PRQIAMYLSRELTESSLPRIGNEFgGKDHTTVIHAHDKItKALKTDAELQKAVGDL 449
Cdd:PRK06030   32 LALAFGVSGAEIASPLRGRREVSrIRQIAMYVAHVSLGWPMNEVALAF-GRDRTTVGHACHTV-EDLRDDAAFDARVSVL 109
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
155-256 6.37e-03

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 38.20  E-value: 6.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 155 LFFYGGVGLGKTHLMHAIGNKLLETDptSNIKYVTSESFTNELINAIQTKKQEAFREEYRNVDLLLVDDIQFFANKEATQ 234
Cdd:pfam01695  95 VVLLGPPGVGKTHLAIALGVEACRAG--YSVRFTSAADLVNQLKRAHGDGKLTRKLQQLLKPDVLILDEWGYLPLDQAEA 172
                          90       100
                  ....*....|....*....|..
gi 2022145540 235 EEFFHTFNALYEdDKQIVLTSD 256
Cdd:pfam01695 173 NLLFQVISKRYE-HRSIILTSN 193
PRK07952 PRK07952
DNA replication protein DnaC; Validated
124-224 6.73e-03

DNA replication protein DnaC; Validated


Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 38.21  E-value: 6.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 124 TFDTFVIGKGNQM-AHAAALVVSEEPGTMYNPLFFYGGVGLGKTHLMHAIGNKLLE----------TDPTSNIKYVTSES 192
Cdd:PRK07952   70 SFENYRVECEGQMnALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLrgksvliitvADIMSAMKDTFSNS 149
                          90       100       110
                  ....*....|....*....|....*....|..
gi 2022145540 193 FTNElinaiqtkkqEAFREEYRNVDLLLVDDI 224
Cdd:PRK07952  150 ETSE----------EQLLNDLSNVDLLVIDEI 171
PRK06620 PRK06620
hypothetical protein; Validated
176-351 7.36e-03

hypothetical protein; Validated


Pssm-ID: 168630  Cd Length: 214  Bit Score: 37.90  E-value: 7.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 176 LLETDPTSNIKYVTSESFTNeLINAIQTKKQEAFREEYRNVDLLLVDDIQFFankeaTQEEFFHTFNALYEDDKQIVLTS 255
Cdd:PRK06620   47 LLIKGPSSSGKTYLTKIWQN-LSNAYIIKDIFFNEEILEKYNAFIIEDIENW-----QEPALLHIFNIINEKQKYLLLTS 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2022145540 256 DRLPNEIpQLQDrLVSRFKWGLSVDITPPDLETrIAILRNKA-DLEGIEIPDDTLSYIAGQIDSNVRELEGALARVQAYS 334
Cdd:PRK06620  121 SDKSRNF-TLPD-LSSRIKSVLSILLNSPDDEL-IKILIFKHfSISSVTISRQIIDFLLVNLPREYSKIIEILENINYFA 197
                         170
                  ....*....|....*..
gi 2022145540 335 RLNNSPITTSLVADALK 351
Cdd:PRK06620  198 LISKRKITISLVKEVLN 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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