|
Name |
Accession |
Description |
Interval |
E-value |
| PFK |
pfam00365 |
Phosphofructokinase; |
2-278 |
1.60e-70 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 220.29 E-value: 1.60e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLA-SADITVF--NGGIPGLLDKNHHEVAWRDLVDFSITSIPIITSGRTSRKLLRSEY 78
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAiYRGHEVYgiRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 79 EIIAKKIKSLRIDVLIMAGGDGSLQFLNTLS-EFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNTGRALp 157
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSH- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 158 GRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKHKLKQQNSVVILCSEGYtreyspgfqGAIDTMIK 237
Cdd:pfam00365 160 NRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELRKGKRFSIIVVAEGA---------SDGEFLAK 230
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2026461395 238 QLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVR 278
Cdd:pfam00365 231 LIEEGTGIETRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
1-325 |
5.86e-63 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 203.00 E-value: 5.86e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQIARLASA-DITV--FNGGIPGLLDknhhevawRDLVDFSITSI-PIITSG----RTSR- 71
Cdd:COG0205 2 KRIGILTSGGDAPGLNAAIRAVVRTAIKyGIEVygIRDGYEGLLE--------GDIIDLTREDVsGILQRGgtilGSSRs 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 72 KLLRSE--YEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF-DINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSR 148
Cdd:COG0205 74 KPFKTEegREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEyGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 149 LRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKHKLKQ-QNSVVILCSEGYTREY--- 224
Cdd:COG0205 154 LRDTAAS-HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRgKGYSIIVVAEGAGDEDgea 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 225 ----------SPGFQGAIDTMIKQLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVRCIQSGMKNKAI-IINS 293
Cdd:COG0205 233 vleadtdafgHVRLGGIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVgIRRG 312
|
330 340 350
....*....|....*....|....*....|..
gi 2026461395 294 SNKPIPIDLVSMKKRLVDTEGHHYKLAKQLNI 325
Cdd:COG0205 313 EIVLVPLEEVANKEKPVDPDSPLIQLARELGI 344
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
1-325 |
1.69e-53 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 177.97 E-value: 1.69e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQIARLASA-DITVFngGIP----GLLDknhhevawRDLVDFSITSI-PIITSG----RTS 70
Cdd:PRK03202 2 KRIGVLTSGGDAPGMNAAIRAVVRTAISeGLEVY--GIYdgyaGLLE--------GDIVKLDLKSVsDIINRGgtilGSA 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 71 RK---LLRSEYEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVS 147
Cdd:PRK03202 72 RFpefKDEEGRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAID 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 148 RLRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKHKLKQ-QNSVVILCSEGYtreysp 226
Cdd:PRK03202 152 RLRDTASS-HERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERgKKHAIIVVAEGV------ 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 227 gfqGAIDTMIKQLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVRCIQSGMKNKAIIInSSNKPIPIDL---V 303
Cdd:PRK03202 225 ---MPAEELAKEIEERTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGI-QNNKIVHVPIeeaV 300
|
330 340
....*....|....*....|..
gi 2026461395 304 SMKKRLVDTEghHYKLAKQLNI 325
Cdd:PRK03202 301 ENMKHPFDKD--LYELAKKLSI 320
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-322 |
1.08e-45 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 158.23 E-value: 1.08e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLA---SADITVFNGGIPGLLDKNHHEVAWRDLVDFSITSIPIITSGRTSRKLLRSEY 78
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAiaeGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCKEFRTEEGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 79 EIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNT 152
Cdd:cd00363 82 AKAAENLKKHGIDALVVIGGDGSYTGADLLTEewpskyQGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRDT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 153 GRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPL---EALAERV-KHKLKQQNSVVILCSEGYTReyspgF 228
Cdd:cd00363 162 ASS-HQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADeweEEMVDVIkKRRERGKRHGIVIVAEGAID-----F 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 229 QGAIDT---MIKQLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVR-----------CIQSGMKNKAIiinss 294
Cdd:cd00363 236 IPKPITeklLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVElllegtggtpvGIQNLNENQVV----- 310
|
330 340
....*....|....*....|....*....
gi 2026461395 295 NKPIpIDLVSMKKRL-VDTEGHHYKLAKQ 322
Cdd:cd00363 311 RHPL-TEAVNMTKRVgVDLEGRPFKKFAK 338
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
1-281 |
5.80e-28 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 114.36 E-value: 5.80e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQIARLASAD-ITVF--NGGIPGLLDKNHHEVAWRDLVDFSITSIPIITsgrTSRKLLRSE 77
Cdd:TIGR02478 390 LRIAIIHVGAPAGGMNAATRSAVRYALARgHTVIaiHNGFSGLARHDVRELTWSDVEGWVGEGGSELG---TNRSLPGDD 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 78 YEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLS-------EFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLR 150
Cdd:TIGR02478 467 LGTIAYYFQQHKIDGLIIIGGFEAFEALYQLDaarekypAFRIPMVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIK 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 151 NTGRALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKHKLKQQNSVV----ILCSEGYTREYSP 226
Cdd:TIGR02478 547 QSASASKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLQEDIEHLKETFAEGRagklILRNEKASKVYTT 626
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2026461395 227 GFqgaIDTMIKQlEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMAcevVRCIQ 281
Cdd:TIGR02478 627 DF---IARIISE-EGKGRFDARTAVLGHMQQGGSPSPFDRVRATRLA---IRAVD 674
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PFK |
pfam00365 |
Phosphofructokinase; |
2-278 |
1.60e-70 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 220.29 E-value: 1.60e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLA-SADITVF--NGGIPGLLDKNHHEVAWRDLVDFSITSIPIITSGRTSRKLLRSEY 78
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAiYRGHEVYgiRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 79 EIIAKKIKSLRIDVLIMAGGDGSLQFLNTLS-EFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNTGRALp 157
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSH- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 158 GRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKHKLKQQNSVVILCSEGYtreyspgfqGAIDTMIK 237
Cdd:pfam00365 160 NRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELRKGKRFSIIVVAEGA---------SDGEFLAK 230
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2026461395 238 QLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVR 278
Cdd:pfam00365 231 LIEEGTGIETRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
1-325 |
5.86e-63 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 203.00 E-value: 5.86e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQIARLASA-DITV--FNGGIPGLLDknhhevawRDLVDFSITSI-PIITSG----RTSR- 71
Cdd:COG0205 2 KRIGILTSGGDAPGLNAAIRAVVRTAIKyGIEVygIRDGYEGLLE--------GDIIDLTREDVsGILQRGgtilGSSRs 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 72 KLLRSE--YEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF-DINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSR 148
Cdd:COG0205 74 KPFKTEegREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEyGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 149 LRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKHKLKQ-QNSVVILCSEGYTREY--- 224
Cdd:COG0205 154 LRDTAAS-HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRgKGYSIIVVAEGAGDEDgea 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 225 ----------SPGFQGAIDTMIKQLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVRCIQSGMKNKAI-IINS 293
Cdd:COG0205 233 vleadtdafgHVRLGGIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVgIRRG 312
|
330 340 350
....*....|....*....|....*....|..
gi 2026461395 294 SNKPIPIDLVSMKKRLVDTEGHHYKLAKQLNI 325
Cdd:COG0205 313 EIVLVPLEEVANKEKPVDPDSPLIQLARELGI 344
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
1-325 |
1.69e-53 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 177.97 E-value: 1.69e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQIARLASA-DITVFngGIP----GLLDknhhevawRDLVDFSITSI-PIITSG----RTS 70
Cdd:PRK03202 2 KRIGVLTSGGDAPGMNAAIRAVVRTAISeGLEVY--GIYdgyaGLLE--------GDIVKLDLKSVsDIINRGgtilGSA 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 71 RK---LLRSEYEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVS 147
Cdd:PRK03202 72 RFpefKDEEGRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAID 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 148 RLRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKHKLKQ-QNSVVILCSEGYtreysp 226
Cdd:PRK03202 152 RLRDTASS-HERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERgKKHAIIVVAEGV------ 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 227 gfqGAIDTMIKQLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVRCIQSGMKNKAIIInSSNKPIPIDL---V 303
Cdd:PRK03202 225 ---MPAEELAKEIEERTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGI-QNNKIVHVPIeeaV 300
|
330 340
....*....|....*....|..
gi 2026461395 304 SMKKRLVDTEghHYKLAKQLNI 325
Cdd:PRK03202 301 ENMKHPFDKD--LYELAKKLSI 320
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-322 |
1.08e-45 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 158.23 E-value: 1.08e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLA---SADITVFNGGIPGLLDKNHHEVAWRDLVDFSITSIPIITSGRTSRKLLRSEY 78
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAiaeGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCKEFRTEEGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 79 EIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNT 152
Cdd:cd00363 82 AKAAENLKKHGIDALVVIGGDGSYTGADLLTEewpskyQGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRDT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 153 GRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPL---EALAERV-KHKLKQQNSVVILCSEGYTReyspgF 228
Cdd:cd00363 162 ASS-HQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADeweEEMVDVIkKRRERGKRHGIVIVAEGAID-----F 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 229 QGAIDT---MIKQLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVR-----------CIQSGMKNKAIiinss 294
Cdd:cd00363 236 IPKPITeklLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVElllegtggtpvGIQNLNENQVV----- 310
|
330 340
....*....|....*....|....*....
gi 2026461395 295 NKPIpIDLVSMKKRL-VDTEGHHYKLAKQ 322
Cdd:cd00363 311 RHPL-TEAVNMTKRVgVDLEGRPFKKFAK 338
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-324 |
7.15e-42 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 147.56 E-value: 7.15e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLASAD-ITVF--NGGIPGLLDKNHHEVAWRDLVDFSITSIPIITSGRTSRKLlrsEY 78
Cdd:cd00763 2 RIGVLTSGGDAPGMNAAIRGVVRSAIAEgLEVYgiRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFPEFK---DE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 79 EIIAKKIKSLR---IDVLIMAGGDGSLQFLNTLSEFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNTGRA 155
Cdd:cd00763 79 EGQAKAIEQLKkhgIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 156 lPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKHKL-KQQNSVVILCSEGYTreyspgfqgAIDT 234
Cdd:cd00763 159 -HQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIeRGKKHAIVVVAEGVY---------DVDE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 235 MIKQLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVRCIQSGMKNKAIIINSS---NKPIpIDLVSMKKRLvd 311
Cdd:cd00763 229 LAKEIEEATGFETRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEqlvHHDI-IDAIENMKPF-- 305
|
330
....*....|...
gi 2026461395 312 tEGHHYKLAKQLN 324
Cdd:cd00763 306 -KKDWLALAKKLS 317
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
1-281 |
5.80e-28 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 114.36 E-value: 5.80e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQIARLASAD-ITVF--NGGIPGLLDKNHHEVAWRDLVDFSITSIPIITsgrTSRKLLRSE 77
Cdd:TIGR02478 390 LRIAIIHVGAPAGGMNAATRSAVRYALARgHTVIaiHNGFSGLARHDVRELTWSDVEGWVGEGGSELG---TNRSLPGDD 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 78 YEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLS-------EFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLR 150
Cdd:TIGR02478 467 LGTIAYYFQQHKIDGLIIIGGFEAFEALYQLDaarekypAFRIPMVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIK 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 151 NTGRALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKHKLKQQNSVV----ILCSEGYTREYSP 226
Cdd:TIGR02478 547 QSASASKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLQEDIEHLKETFAEGRagklILRNEKASKVYTT 626
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2026461395 227 GFqgaIDTMIKQlEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMAcevVRCIQ 281
Cdd:TIGR02478 627 DF---IARIISE-EGKGRFDARTAVLGHMQQGGSPSPFDRVRATRLA---IRAVD 674
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
2-303 |
2.55e-26 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 109.35 E-value: 2.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLA---SADITVFNGGIPGLLD--KNHHEVAWRDLVdfSITSI--PIITSGR-----T 69
Cdd:TIGR02478 2 RIAVLTSGGDAQGMNAAVRAVVRMAiyvGCRVYAIREGYQGLVDggDNIEEAQWEDVR--GILSLggTIIGTARckefrE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 70 SRKLLRSEYEIIAKkikslRIDVLIMAGGDGSLQFLNTLSE-------------------------FDIncfgVGM--TI 122
Cdd:TIGR02478 80 RPGRLKAARNLVSN-----GIDALVVIGGDGSLTGADLFREewpslleelvdtgkitaeqaeehrhLTI----VGLvgSI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 123 DNDVYGSDYTIGFSTACEQIIKEVSRLRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQmPLEALAERV 202
Cdd:TIGR02478 151 DNDMCGTDMTIGADSALHRICEAIDAISSTAQS-HQRAFVVEVMGRHCGYLALMAAIATGADYVFIPERP-PEEGWEDQL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 203 KHKLK------QQNSVVILCsegytreyspgfQGAIDT--------MIKQ-LEPQIGVRIRKTIVGYGLRSGDPTCEEIY 267
Cdd:TIGR02478 229 CHKLKrnrkagKRKTIVIVA------------EGAIDRdlnpitseDVKDvLVERLGLDTRITVLGHVQRGGAPSAFDRI 296
|
330 340 350
....*....|....*....|....*....|....*...
gi 2026461395 268 QGTIMACEVVRCIQSGMKNK--AIIINSSNKPIPIDLV 303
Cdd:TIGR02478 297 LATRQGVEAVLAVLESTPETpsPVISLRGNKIVRKPLV 334
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
1-285 |
1.11e-23 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 101.82 E-value: 1.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQIARLASAD---ITVFNGGIPGLLDKNHHEVAWRDLVDFSITSIPIITsgrTSRKLLRSE 77
Cdd:cd00764 390 LNIAIVNVGAPAAGMNAAVRSAVRYGLAHghrPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELG---TKRTLPKKD 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 78 YEIIAKKIKSLRIDVLIMAGG----DGSLQFLNTLSEFDINCFGVGM---TIDNDVYGSDYTIGFSTACEQIIKEVSRLR 150
Cdd:cd00764 467 LETIAYNFQKYGIDGLIIVGGfeayKGLLQLREAREQYEEFCIPMVLipaTVSNNVPGTDFSLGSDTALNALMKYCDRIK 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 151 NTGRALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKH-----KLKQQNSVV---ILCSEGYTR 222
Cdd:cd00764 547 QSASGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQENVEHltekmKTTIGRGLVlrnEKCNENYTT 626
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2026461395 223 EYSPgfqgaidtmikQLEPQIGVRI---RKTIVGYGLRSGDPTCEEIYQGTIMACEVVRCIQSGMK 285
Cdd:cd00764 627 VFTY-----------ELYSEEGKGVfdcRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWIEQKLK 681
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
2-325 |
2.40e-23 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 98.60 E-value: 2.40e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLASA----DITVFNGGIPGLLDKNHHEVAW-RDLVDfsitsiPIITSGRT------- 69
Cdd:PRK14071 6 RIGILTSGGDCAGLNAVIRAVVHRARGtygwEVIGIRDATQGLMARPPQYIELdLDQVD------DLLRMGGTilgttnk 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 70 ----------SRKLLRSEyEIIAKkIKSLRIDVLIMAGGDGSLQFLNTLSEF-DINCFGVGMTIDNDVYGSDYTIGFSTA 138
Cdd:PRK14071 80 gdpfafpmpdGSLRDRSQ-EIIDG-YHSLGLDALIGIGGDGSLAILRRLAQQgGINLVGIPKTIDNDVGATEVSIGFDTA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 139 CEQIIKEVSRLRNTGrALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLEALAERVKH-KLKQQNSVVILCS 217
Cdd:PRK14071 158 VNIATEALDRLHFTA-ASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENVCKKIRErQEEGKNFCLVVVS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 218 EG--------YTREYSPG---FQGAIDTMIKQLEPQIGVRIRKTIVGYGLRSGDPTCEEIYQGTIMACEVVRCIQSGMKN 286
Cdd:PRK14071 237 EAvrteegeqVTKTQALGedrYGGIGQYLAEQIAERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQGKFD 316
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 2026461395 287 KAIII-NSSNKPIPIDLVSMKKRLVDTEGHHYKLAKQLNI 325
Cdd:PRK14071 317 RMVAWqNRQVVSVPIAEAIATYRAVDPEGTLVKTARGLGI 356
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-280 |
1.04e-21 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 95.66 E-value: 1.04e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLA---SADITVFNGGIPGLLDKNHH--EVAWRDLVDFSITSIPIITSGR-----TSR 71
Cdd:cd00764 5 AIAVLTSGGDAQGMNAAVRAVVRMGiyvGAKVFFVYEGYEGLVKGGDYikQAEWESVSNWLQEGGTIIGSARckefrERE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 72 KLLRSEYEIIAKKikslrIDVLIMAGGDGSLQFLNTL-SEF----------------------DINCFGVGMTIDNDVYG 128
Cdd:cd00764 85 GRLQAAYNLIQRG-----ITNLCVIGGDGSLTGADLFrSEWpslleelvkdgkiteeevakyqHLNIVGMVGSIDNDFCG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 129 SDYTIGFSTACEQIIKEVSRLRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMP---LEALAERV-KH 204
Cdd:cd00764 160 TDMTIGTDSALHRICEVVDAITTTAQS-HQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPEdgwEDQMCRRLsEH 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 205 KLKQQNSVVILCSEgytreyspgfqGAIDtmiKQLEP------------QIGVRIRKTIVGYGLRSGDPTCEEIYQGTIM 272
Cdd:cd00764 239 RSRGKRLNIIIVAE-----------GAID---DQLKPitsedvkdlvveRLGLDTRVTTLGHVQRGGTPSAFDRILASLM 304
|
....*...
gi 2026461395 273 ACEVVRCI 280
Cdd:cd00764 305 GVEAVMAL 312
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
2-254 |
5.35e-20 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 90.10 E-value: 5.35e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLASADITV-----FNGGIPGLLDKNHHEVAWRDLVDFSITSIPIITSGRTSRKLlrs 76
Cdd:PTZ00286 89 KAGIVTCGGLCPGLNVVIRELVMNLINNYGVktiygAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSRGGFDP--- 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 77 eyEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLR 150
Cdd:PTZ00286 166 --KVMVDTLIRHGINILFTLGGDGTHRGALAIYKelrrrkLNISVVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAY 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 151 NTGRALPGRVFMVEILGGYCGELTLQSAIKS-NADIALIPESQMPLEALAERVKHKLKQQNSVVILCSEGYTREYSPG-F 228
Cdd:PTZ00286 244 VEAKSAKNGVGIVKLMGRDSGFIALHASVASaDVNVCLIPEFDIPLEGVLEYIEQRLQKKGHCVIVVAEGAGQSLKDAdL 323
|
250 260
....*....|....*....|....*.
gi 2026461395 229 QGAIDTMIKQLEPQIGVRIRKTIVGY 254
Cdd:PTZ00286 324 DLGTDASGNKKLWDIGVYLKDEITKY 349
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
1-261 |
3.48e-12 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 66.76 E-value: 3.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQIA----RLASADITVFNGGIPGLLDKNHHEVAW-RDLVDfsitsiPIITSGRTSRKLLR 75
Cdd:PLN02884 54 VKAAIVTCGGLCPGLNDVIRQIVftleIYGVKNIVGIPFGYRGFFEKGLSEMPLsRKVVQ------NIHLSGGSLLGVSR 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 76 SEYEI--IAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVS 147
Cdd:PLN02884 128 GGAKTsdIVDSIEARGINMLFVLGGNGTHAGANAIHNecrkrkMKVSVVGVPKTIDNDILLMDKTFGFDTAVEEAQRAIN 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 148 RLRNTGRALPGRVFMVEILGGYCGELTLQSAIKS-NADIALIPESQMPL---EALAERVKHKLKQQNSVVILCSEGYTRE 223
Cdd:PLN02884 208 SAYIEAHSAYHGIGLVKLMGRSSGFIAMHASLASgQVDICLIPEVPFTLdgpNGVLRHLEHLIETKGSAVVCVAEGAGQD 287
|
250 260 270
....*....|....*....|....*....|....*...
gi 2026461395 224 YSPGfQGAIDTMIKQLEPQIGVRIRKTIVGYGLRSGDP 261
Cdd:PLN02884 288 LLQK-TNATDASGNPVLGDIGVHLQQEIKKHFKDIGVP 324
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
75-219 |
4.42e-12 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 66.42 E-value: 4.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 75 RSEYEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF------DINCFGVGMTIDNDVYGSDYTIGFSTACEQI---IKE 145
Cdd:PRK14072 89 RAEYERLLEVFKAHDIGYFFYNGGNDSMDTALKVSQLakkmgyPIRCIGIPKTIDNDLPGTDHCPGFGSAAKYIatsVLE 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 146 VSrLRNtgRALPG--RVFMVEILGGYCGELTLQSAIKSN-----ADIALIPESQMPLEALAERVKHKLKQQNSVVILCSE 218
Cdd:PRK14072 169 AA-LDV--AAMANtsKVFILEVMGRHAGWLAAAAALAKQnpddaPHLIYLPERPFDEEKFLADVRAIVKRYGYCVVVVSE 245
|
.
gi 2026461395 219 G 219
Cdd:PRK14072 246 G 246
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
1-238 |
6.95e-12 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 66.60 E-value: 6.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQIARLA-----SADITVFNGGIPGLLDKNHHEVA------WRDLVDFSitsipIITSGRT 69
Cdd:PTZ00287 178 LKIGIILSGGPAPGGHNVISGIYDYAkryneQSQVIGFLGGIDGLYSKNYVTITdslmnrFRNLGGFN-----MLWSGRG 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 70 SrklLRSEYEIIAKK--IKSLRIDVLIMAGGDGSLQFLNTLSEF------DINCFGVGMTIDNDVYGS--DYTIGFSTAC 139
Cdd:PTZ00287 253 K---VRNKDDLIAIEniVAKLKLNGLVIIGGDGSNSNAALISEYfaerqiPISIIGIPKTIDGDLKSEaiEISFGFDTAT 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 140 E---QIIKEVSRLRNTGRALpgrVFMVEILGGYCGELTLQSAIKSNADIALIPES----QMPLEALAERV-----KHKLK 207
Cdd:PTZ00287 330 KtysEVIGNLCTDVKTGHNV---YHVVRVMGRSASHVVLECALQTRPNIVLIGEEvekeNLSLKDIVSNIvntilKRRSL 406
|
250 260 270
....*....|....*....|....*....|....
gi 2026461395 208 QQNSVVILCSEGYTrEYSPGFQ---GAIDTMIKQ 238
Cdd:PTZ00287 407 NKNYGVILIPEGLI-EFVPEMKiliGELNVILKE 439
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
2-254 |
3.51e-10 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 60.65 E-value: 3.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARLAS-----ADITVFNGGIPGLLDKNHHEVAwrDLVDFSITSI-----PIITSGRTSR 71
Cdd:PRK06830 82 KAAIVTCGGLCPGLNDVIRAIVLELHhhygvRRILGIRYGYQGLIPRYGHDPV--ELTPEVVADIhefggTILGSSRGPQ 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 72 KLlrseyEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKE 145
Cdd:PRK06830 160 DP-----EEIVDTLERMNINILFVIGGDGTLRGASAIAEeierrgLKISVIGIPKTIDNDINFIQKSFGFETAVEKATEA 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 146 VSRLRNTGRALPGRVFMVEILGGYCGELTLQSAI-KSNADIALIPESQMPLE---ALAERVKHKLKQQNSVVILCSEGYT 221
Cdd:PRK06830 235 IRCAHVEANGAPNGIGLVKLMGRHSGFIAAYAALaSKDVNFVLIPEVPFDLEgpnGLLAALEKRLAERGHAVIVVAEGAG 314
|
250 260 270
....*....|....*....|....*....|...
gi 2026461395 222 REYSPGFQGAIDTMIKQLEpQIGVRIRKTIVGY 254
Cdd:PRK06830 315 QELFDDTGETDASGNPKLG-DIGLFLKDRIKEY 346
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
1-240 |
1.40e-09 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 58.78 E-value: 1.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFI---FQIARLASADITVFN--GGIPGLLDKNHHEVAwRDLVDFSITS--IPIITSGRTsrKL 73
Cdd:PRK07085 71 LKVGVILSGGQAPGGHNVIaglFDGLKKLNPDSKLFGfiGGPLGLLNGKYIEIT-EEVIDEYRNTggFDMIGSGRT--KI 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 74 LRSE-YEIIAKKIKSLRIDVLIMAGGDGSlqflNT----LSEF------DINCFGVGMTIDNDVYGS--DYTIGFSTACE 140
Cdd:PRK07085 148 ETEEqKEACLETVKKLKLDGLVIIGGDDS----NTnaaiLAEYfakhgcKTQVIGVPKTIDGDLKNEfiETSFGFDTATK 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 141 ---QIIKEVSRLRNTGRALpgrVFMVEILGGYCGELTLQSAIKSNADIALIPE----SQMPLEALAER-----VKHKLKQ 208
Cdd:PRK07085 224 tysEMIGNISRDALSAKKY---WHFIKLMGRSASHIALECALQTHPNICLISEevaeKKMSLQDIVHYiasviADRAAKG 300
|
250 260 270
....*....|....*....|....*....|..
gi 2026461395 209 QNSVVILCSEGYTrEYSPgfqgAIDTMIKQLE 240
Cdd:PRK07085 301 KNYGVILIPEGLI-EFIP----EMKSLIKELN 327
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
1-190 |
6.19e-09 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 56.80 E-value: 6.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFI---FQIARLASADITV--FNGGIPGLLDKNHHEV------AWRDLVDFSitsipIITSGRT 69
Cdd:cd00765 73 LKIGIVLSGGQAPGGHNVIsglFDYLKERAKGSTLygFKGGPAGILKCDYIELnaeyiqPYRNTGGFD-----MICSGRT 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 70 SRKlLRSEYEIIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF------DINCFGVGMTIDNDVYGSDYTI--GFSTACEQ 141
Cdd:cd00765 148 KIE-TEDQFKQAEETAKKLDLDALVVIGGDDSNTNAALLAENfrskglKTRVIGVPKTIDGDLKNKEIETsfGFDTATKI 226
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2026461395 142 IIKEVSRLRNTGRALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPE 190
Cdd:cd00765 227 YSELIGNVMRDARSTGKYWHFVKLMGRSASHIALECALKTHPNICIISE 275
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
79-240 |
5.35e-08 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 53.86 E-value: 5.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 79 EIIAKKIKSLRIDVLIMAGGDGSlqflNT--------LSE--FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSR 148
Cdd:PRK06555 102 KVAAERLAADGVDILHTIGGDDT----NTtaadlaayLAEngYDLTVVGLPKTIDNDVVPIRQSLGAWTAAEQGARFFDN 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 149 LRNTGRALPgRVFMV-EILGGYCGELTLQSAIK--------------------SNADIALIPESQMPLEALAERVKHKLK 207
Cdd:PRK06555 178 VINEHSANP-RMLIIhEVMGRNCGWLTAATARAyrewldrqeyvpgfglsaerWDIHAVYLPEMAFDLEAEAERLKAVMD 256
|
170 180 190
....*....|....*....|....*....|...
gi 2026461395 208 QQNSVVILCSEGytreyspgfqGAIDTMIKQLE 240
Cdd:PRK06555 257 EVGNVNIFLSEG----------AGLDAIVAEME 279
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
2-239 |
9.38e-08 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 53.82 E-value: 9.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 2 KIGIVISGGDVSGINNFIFQIARL-----ASADITVFNGGIPGLLDKNHHEVAWRDLVDF-SITSIPIITSGR---TSRK 72
Cdd:PTZ00468 104 RIGVVLSGGQASGGHNVIAGLMSYiklcnQSSQLFGFLGGPEGVYSERYRELTEDDINGIlNQGGFNIICSGRhkiETEE 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 73 LLRSEYEIIAKkiksLRIDVLIMAGGDGSLQFLNTLSEF------DINCFGVGMTIDNDVYGS--DYTIGFSTA----CE 140
Cdd:PTZ00468 184 QMRASLEICEK----LKLHGLVVIGGDDSNTNAAVLAEYfkrnssSTVVVGCPKTIDGDLKNEviETSFGYDTAvktySE 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 141 QIIKEVSRLRNTGRalpgRVFMVEILGGYCGELTLQSAIKSNADIAL----IPESQMPLEALAERVKHKLKQQNSV---- 212
Cdd:PTZ00468 260 QIGSIMDAIKTEGY----GYYFVRLMGRSASHITLECGLQTRANMILigeeIKEENRSLMSIVDEIVEMILKRDSLgkkh 335
|
250 260
....*....|....*....|....*...
gi 2026461395 213 -VILCSEGYTrEYSPGFQgaidTMIKQL 239
Cdd:PTZ00468 336 gIVLLPEGLI-EFIPEFE----TLIKEL 358
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
81-224 |
1.49e-07 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 52.44 E-value: 1.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 81 IAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNTGR 154
Cdd:PLN02564 168 IVDSIQDRGINQVYIIGGDGTQKGASVIYEeirrrgLKVAVAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAE 247
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2026461395 155 ALPGRVFMVEILGGYCGELTLQSAIKS-NADIALIPESQMPLE---ALAERVKHKLKQQNSVVILCSEGYTREY 224
Cdd:PLN02564 248 SVENGIGLVKLMGRYSGFIAMYATLASrDVDCCLIPESPFYLEgkgGLFEFIEKRLKENGHMVIVVAEGAGQDL 321
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
1-190 |
3.02e-05 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 45.55 E-value: 3.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 1 MKIGIVISGGDVSGINNFIFQI-----ARLASADITVFNGGIPGLLDKNHHEVA------WRDLVDFSitsipIITSGR- 68
Cdd:PLN02251 97 LKIGVVLSGGQAPGGHNVISGIfdylqEHAKGSVLYGFKGGPAGIMKCKYVELTaefiypYRNQGGFD-----MICSGRd 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2026461395 69 ---TSRKLLRSEyeiiaKKIKSLRIDVLIMAGGDGSlqflNT----LSEF------DINCFGVGMTIDNDVYGSDYTI-- 133
Cdd:PLN02251 172 kieTPEQFKQAE-----ETATKLDLDGLVVIGGDDS----NTnaclLAEYfraknlKTRVIGCPKTIDGDLKSKEVPTsf 242
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2026461395 134 GFSTAC----EQIIKEVSRLRNTGRALpgrvFMVEILGGYCGELTLQSAIKSNADIALIPE 190
Cdd:PLN02251 243 GFDTACkiysEMIGNVMIDARSTGKYY----HFVRLMGRAASHITLECALQTHPNITIIGE 299
|
|
| |
