|
Name |
Accession |
Description |
Interval |
E-value |
| RpiR |
COG1737 |
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains ... |
1-277 |
2.43e-73 |
|
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains [Transcription];
Pssm-ID: 441343 [Multi-domain] Cd Length: 286 Bit Score: 226.35 E-value: 2.43e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 1 MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTGID- 79
Cdd:COG1737 5 MSLLERIRARYPSLSPSERRIADYILDNPEEVAFMSIAELAEAAGVSEATVVRFCRKLGFSGFPELKLALAQELAEGLSs 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 80 -EGFSDIEANESFYSIKNKLGNNAQVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPII 158
Cdd:COG1737 85 yERLRRLSPDDSLEDILAKVLEAEIANLEETLELLDEEALERAVDLLAKARRIYIFGVGASAPVAEDLAYKLLRLGKNVV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 159 F-EKDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRPkEITNRSA 237
Cdd:COG1737 165 LlDGDGHLQAESAALLGPGDVVIAISFSGYTRETLEAARLAKERGAKVIAITDSPLSPLAKLADVVLYVPSE-EPTLRSS 243
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2045666817 238 ATNSLLAQFATIDIIFYFYMAKN-EKLSEKVKKTREAIQEY 277
Cdd:COG1737 244 AFSSRVAQLALIDALAAAVAQRDgDKARERLERTEALLSEL 284
|
|
| SIS_RpiR |
cd05013 |
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many ... |
116-255 |
1.88e-35 |
|
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate.
Pssm-ID: 240144 [Multi-domain] Cd Length: 139 Bit Score: 124.26 E-value: 1.88e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 116 ETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFEKDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALA 195
Cdd:cd05013 1 EALEKAVDLLAKARRIYIFGVGSSGLVAEYLAYKLLRLGKPVVLLSDPHLQLMSAANLTPGDVVIAISFSGETKETVEAA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 196 ELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRPkEITNRSAATNSLLAQFATIDIIFYF 255
Cdd:cd05013 81 EIAKERGAKVIAITDSANSPLAKLADIVLLVSSE-EGDFRSSAFSSRIAQLALIDALFLA 139
|
|
| PRK11337 |
PRK11337 |
MurR/RpiR family transcriptional regulator; |
2-275 |
2.16e-32 |
|
MurR/RpiR family transcriptional regulator;
Pssm-ID: 183089 [Multi-domain] Cd Length: 292 Bit Score: 120.64 E-value: 2.16e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 2 SVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEG 81
Cdd:PRK11337 14 GLGPYIRMKQEGLTPLESRVVEWLLKPGDLSEATALKDIAEALAVSEAMIVKVAKKLGFSGFRNLRSALEDYFSQSEQVL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 82 FSDIEANESFYSIKNKLGNNAQVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFEK 161
Cdd:PRK11337 94 HSELSFDDAPQDVVNKVFNTSLQAIEETQSILDVDEFHRAARFFYQARQRDLYGAGGSAAIARDVQHKFLRIGVRCQAYD 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 162 DIHV-LLPQLVSNEKKKVLwLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIAD-VLVQTSRPKEITNRSAAt 239
Cdd:PRK11337 174 DAHImLMSAALLQEGDVVL-VVSHSGRTSDVIEAVELAKKNGAKIICITNSYHSPIAKLADyVICSTAQGSPLLGENAA- 251
|
250 260 270
....*....|....*....|....*....|....*..
gi 2045666817 240 nSLLAQFATIDIIFYFYMAKNEKLSEK-VKKTREAIQ 275
Cdd:PRK11337 252 -ARIAQLNILDAFFVSVAQLNIEQAEInLQKTGAAVD 287
|
|
| HTH_6 |
pfam01418 |
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best ... |
1-77 |
2.79e-12 |
|
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best characterized member of this family is Swiss:P39266. RpiR is a regulator of the expression of rpiB gene.
Pssm-ID: 334531 [Multi-domain] Cd Length: 77 Bit Score: 61.19 E-value: 2.79e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2045666817 1 MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTG 77
Cdd:pfam01418 1 MGLLEKIQSRYSKLTKSERKIADYILAHPDLAIHLSISAIAKAAGVSEATIVRFCQKLGFSGFPELKLALAGELANS 77
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| RpiR |
COG1737 |
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains ... |
1-277 |
2.43e-73 |
|
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains [Transcription];
Pssm-ID: 441343 [Multi-domain] Cd Length: 286 Bit Score: 226.35 E-value: 2.43e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 1 MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTGID- 79
Cdd:COG1737 5 MSLLERIRARYPSLSPSERRIADYILDNPEEVAFMSIAELAEAAGVSEATVVRFCRKLGFSGFPELKLALAQELAEGLSs 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 80 -EGFSDIEANESFYSIKNKLGNNAQVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPII 158
Cdd:COG1737 85 yERLRRLSPDDSLEDILAKVLEAEIANLEETLELLDEEALERAVDLLAKARRIYIFGVGASAPVAEDLAYKLLRLGKNVV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 159 F-EKDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRPkEITNRSA 237
Cdd:COG1737 165 LlDGDGHLQAESAALLGPGDVVIAISFSGYTRETLEAARLAKERGAKVIAITDSPLSPLAKLADVVLYVPSE-EPTLRSS 243
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2045666817 238 ATNSLLAQFATIDIIFYFYMAKN-EKLSEKVKKTREAIQEY 277
Cdd:COG1737 244 AFSSRVAQLALIDALAAAVAQRDgDKARERLERTEALLSEL 284
|
|
| SIS_RpiR |
cd05013 |
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many ... |
116-255 |
1.88e-35 |
|
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate.
Pssm-ID: 240144 [Multi-domain] Cd Length: 139 Bit Score: 124.26 E-value: 1.88e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 116 ETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFEKDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALA 195
Cdd:cd05013 1 EALEKAVDLLAKARRIYIFGVGSSGLVAEYLAYKLLRLGKPVVLLSDPHLQLMSAANLTPGDVVIAISFSGETKETVEAA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 196 ELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRPkEITNRSAATNSLLAQFATIDIIFYF 255
Cdd:cd05013 81 EIAKERGAKVIAITDSANSPLAKLADIVLLVSSE-EGDFRSSAFSSRIAQLALIDALFLA 139
|
|
| PRK11337 |
PRK11337 |
MurR/RpiR family transcriptional regulator; |
2-275 |
2.16e-32 |
|
MurR/RpiR family transcriptional regulator;
Pssm-ID: 183089 [Multi-domain] Cd Length: 292 Bit Score: 120.64 E-value: 2.16e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 2 SVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEG 81
Cdd:PRK11337 14 GLGPYIRMKQEGLTPLESRVVEWLLKPGDLSEATALKDIAEALAVSEAMIVKVAKKLGFSGFRNLRSALEDYFSQSEQVL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 82 FSDIEANESFYSIKNKLGNNAQVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFEK 161
Cdd:PRK11337 94 HSELSFDDAPQDVVNKVFNTSLQAIEETQSILDVDEFHRAARFFYQARQRDLYGAGGSAAIARDVQHKFLRIGVRCQAYD 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 162 DIHV-LLPQLVSNEKKKVLwLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIAD-VLVQTSRPKEITNRSAAt 239
Cdd:PRK11337 174 DAHImLMSAALLQEGDVVL-VVSHSGRTSDVIEAVELAKKNGAKIICITNSYHSPIAKLADyVICSTAQGSPLLGENAA- 251
|
250 260 270
....*....|....*....|....*....|....*..
gi 2045666817 240 nSLLAQFATIDIIFYFYMAKNEKLSEK-VKKTREAIQ 275
Cdd:PRK11337 252 -ARIAQLNILDAFFVSVAQLNIEQAEInLQKTGAAVD 287
|
|
| PRK11557 |
PRK11557 |
MurR/RpiR family transcriptional regulator; |
6-253 |
1.08e-30 |
|
MurR/RpiR family transcriptional regulator;
Pssm-ID: 183195 [Multi-domain] Cd Length: 278 Bit Score: 116.02 E-value: 1.08e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 6 RIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEG---- 81
Cdd:PRK11557 2 RIRQRYPGLAQSDRKLADYLLLQPDTARHLSSQQLANEAGVSQSSVVKFAQKLGYKGFPALKLALSEALASQPEPPsvpv 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 82 FSDIEANESFYSIKNKLGNNAQVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFEK 161
Cdd:PRK11557 82 HNQIRGDDPLRLVGEKLIKENTAAMRATLDVNSEEKLHECVTMLRSARRIILTGIGASGLVAQNFAWKLMKIGINAVAER 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 162 DIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQTSrPKEITNRSAATNS 241
Cdd:PRK11557 162 DMHALLATVQALSPDDLLLAISYSGERRELNLAADEALRVGAKVLAITGFTPNALQQRASHCLYTI-AEEQATRSAAISS 240
|
250
....*....|..
gi 2045666817 242 LLAQFATIDIIF 253
Cdd:PRK11557 241 THAQGMLTDLLF 252
|
|
| PRK15482 |
PRK15482 |
HTH-type transcriptional regulator MurR; |
1-275 |
1.75e-28 |
|
HTH-type transcriptional regulator MurR;
Pssm-ID: 185379 [Multi-domain] Cd Length: 285 Bit Score: 110.17 E-value: 1.75e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 1 MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDE 80
Cdd:PRK15482 1 MLYLTKIRNAESEFTENEQKIADFLRANVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 81 G-------FSDIEANESFYSIKNKLGNNAQVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRV 153
Cdd:PRK15482 81 TnatalhlHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 154 GKPIIFEKDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRpKEIT 233
Cdd:PRK15482 161 GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVS-GETE 239
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 2045666817 234 NRSAATNSLLAQFATIDIIFYFYMAKNEKLSEK-VKKTREAIQ 275
Cdd:PRK15482 240 WRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKmIQRSSELTQ 282
|
|
| PRK14101 |
PRK14101 |
bifunctional transcriptional regulator/glucokinase; |
2-252 |
1.97e-28 |
|
bifunctional transcriptional regulator/glucokinase;
Pssm-ID: 184507 [Multi-domain] Cd Length: 638 Bit Score: 114.24 E-value: 1.97e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 2 SVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEG 81
Cdd:PRK14101 342 AVFERIRQMRDALTPAERRVADLALNHPRSIINDPIVDIARKADVSQPTVIRFCRSLGCQGLSDFKLKLATGLTGTIPMS 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 82 FSDIEANESFYSIKNKLGNNAQVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFEK 161
Cdd:PRK14101 422 HSQVHLGDTATDFGAKVLDNTVSAILQLREHLNFEHVEQAIDILNNARRIEFYGLGNSNIVAQDAHYKFFRFGIPTIAYG 501
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 162 DIHVllpQLVSNE---KKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQfGNNPLSKIADVLVQTSRPkEITNRSAA 238
Cdd:PRK14101 502 DLYM---QAASAAllgKGDVIVAVSKSGRAPELLRVLDVAMQAGAKVIAITS-SNTPLAKRATVALETDHI-EMRESQLS 576
|
250
....*....|....
gi 2045666817 239 TNSLLAQFATIDII 252
Cdd:PRK14101 577 MISRILHLVMIDIL 590
|
|
| PRK11302 |
PRK11302 |
DNA-binding transcriptional regulator HexR; Provisional |
1-276 |
2.53e-23 |
|
DNA-binding transcriptional regulator HexR; Provisional
Pssm-ID: 183082 [Multi-domain] Cd Length: 284 Bit Score: 96.22 E-value: 2.53e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 1 MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDE 80
Cdd:PRK11302 1 MNMLEKIQSRLEHLSKSERKVAEVILASPQTAIHSSIATLAKMANVSEPTVNRFCRSLDTKGFPDFKLHLAQSLANGTPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 81 GFSDIEANESFYSIKNKLGNNAQVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE 160
Cdd:PRK11302 81 VNRNVEEDDSVEAYTGKIFESAMASLDHARQSLDPSAINRAVDLLTQAKKISFFGLGASAAVAHDAQNKFFRFNVPVVYF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 161 KDIhVLLPQLVSN-EKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQfGNNPLSKIADVLVQTSRPkEITNRSAAT 239
Cdd:PRK11302 161 DDI-VMQRMSCMNsSDGDVVVLISHTGRTKSLVELAQLARENGATVIAITS-AGSPLAREATLALTLDVP-EDTDIYMPM 237
|
250 260 270
....*....|....*....|....*....|....*...
gi 2045666817 240 NSLLAQFATIDIIFY-FYMAKNEKLSEKVKKTREAIQE 276
Cdd:PRK11302 238 VSRIAQLTVIDVLATgFTLRRGAKFRDNLKRVKEALKE 275
|
|
| HTH_6 |
pfam01418 |
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best ... |
1-77 |
2.79e-12 |
|
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best characterized member of this family is Swiss:P39266. RpiR is a regulator of the expression of rpiB gene.
Pssm-ID: 334531 [Multi-domain] Cd Length: 77 Bit Score: 61.19 E-value: 2.79e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2045666817 1 MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEASGLSAPTVVRFSKKIGFQSLTDFKITISTELQTG 77
Cdd:pfam01418 1 MGLLEKIQSRYSKLTKSERKIADYILAHPDLAIHLSISAIAKAAGVSEATIVRFCQKLGFSGFPELKLALAGELANS 77
|
|
| SIS |
pfam01380 |
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
125-253 |
2.86e-11 |
|
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars. Presumably the SIS domains bind to the end-product of the pathway.
Pssm-ID: 426230 [Multi-domain] Cd Length: 131 Bit Score: 59.62 E-value: 2.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 125 LESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFEKDIHVLLPQLVSN-EKKKVLWLVSNSGRSADVVALAELAKSMNI 203
Cdd:pfam01380 2 LAKAKRIFVIGRGTSYAIALELALKFEEIGYKVVEVELASELRHGVLALvDEDDLVIAISYSGETKDLLAAAELAKARGA 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 2045666817 204 EIIALTQFGNNPLSKIADVLVQTSRPKEITNrsAATNSLLAQFATIDIIF 253
Cdd:pfam01380 82 KIIAITDSPGSPLAREADHVLYINAGPETGV--ASTKSITAQLAALDALA 129
|
|
| AgaS |
COG2222 |
Fructoselysine-6-P-deglycase FrlB or related protein, duplicated sugar isomerase (SIS) domain ... |
182-276 |
2.16e-09 |
|
Fructoselysine-6-P-deglycase FrlB or related protein, duplicated sugar isomerase (SIS) domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441824 [Multi-domain] Cd Length: 336 Bit Score: 57.22 E-value: 2.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 182 VSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRPKEitnRS-AATNSLLAQFATIDIIFyFYMAKN 260
Cdd:COG2222 89 ISRSGNSPEVVAALELAKARGARTLAITNNPDSPLAEAADRVLPLPAGPE---KSvAATKSFTTMLLALLALL-AAWGGD 164
|
90
....*....|....*.
gi 2045666817 261 EKLSEKVKKTREAIQE 276
Cdd:COG2222 165 DALLAALDALPAALEA 180
|
|
| SIS_Kpsf |
cd05014 |
KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ... |
178-247 |
2.24e-08 |
|
KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose 5-phosphate to arabinose 5-phosphate. This is the second step in the CMP-Kdo biosynthesis pathway.
Pssm-ID: 240145 [Multi-domain] Cd Length: 128 Bit Score: 51.77 E-value: 2.24e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2045666817 178 VLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRPKEI-TNRSAATNSLLAQFA 247
Cdd:cd05014 50 VVIAISNSGETDELLNLLPHLKRRGAPIIAITGNPNSTLAKLSDVVLDLPVEEEAcPLGLAPTTSTTAMLA 120
|
|
| GutQ |
COG0794 |
D-arabinose 5-phosphate isomerase GutQ [Carbohydrate transport and metabolism, Cell wall ... |
178-247 |
2.47e-07 |
|
D-arabinose 5-phosphate isomerase GutQ [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440557 [Multi-domain] Cd Length: 317 Bit Score: 51.13 E-value: 2.47e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2045666817 178 VLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRPKEI--TNRsAATNSLLAQFA 247
Cdd:COG0794 94 VVIAISNSGETEELLALLPLLKRLGVPLIAITGNPDSTLARAADVVLDLPVEREAcpLNL-APTTSTTATLA 164
|
|
| SIS_PHI |
cd05005 |
Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) ... |
106-225 |
2.77e-07 |
|
Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with formadelhyde to become hexulose-6-phosphate, which is then isomerized to fructose-6-phosphate by PHI.
Pssm-ID: 240138 [Multi-domain] Cd Length: 179 Bit Score: 49.50 E-value: 2.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 106 IKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIifekdiHVL----LPQLVSNEkkkVLWL 181
Cdd:cd05005 11 IENVADKIDEEELDKLISAILNAKRIFVYGAGRSGLVAKAFAMRLMHLGLNV------YVVgettTPAIGPGD---LLIA 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2045666817 182 VSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQ 225
Cdd:cd05005 82 ISGSGETSSVVNAAEKAKKAGAKVVLITSNPDSPLAKLADVVVV 125
|
|
| SIS_GmhA |
cd05006 |
Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose ... |
115-225 |
4.56e-07 |
|
Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of gram-negative bacteria inner core lipopolysaccharide precursor, L-glycero-D-mannoheptose (Gmh).
Pssm-ID: 240139 [Multi-domain] Cd Length: 177 Bit Score: 49.05 E-value: 4.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 115 EETIQKVVECLESAETVFLYGVGAS----SLVVEDILQKWSRVGKPI-----------------------IFEKDIHVLL 167
Cdd:cd05006 20 EQAAQLLAEALLNGGKILICGNGGSaadaQHFAAELVKRFEKERPGLpaialttdtsiltaiandygyeeVFSRQVEALG 99
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2045666817 168 pqlvsnEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQ 225
Cdd:cd05006 100 ------QPGDVLIGISTSGNSPNVLKALEAAKERGMKTIALTGRDGGKLLELADIEIH 151
|
|
| SIS_2 |
pfam13580 |
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
105-209 |
2.94e-05 |
|
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 433326 [Multi-domain] Cd Length: 138 Bit Score: 42.97 E-value: 2.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 105 AIKETVDILEEETIQKVVE----CLESAETVFLYGVGASSLVVEDIlqkWSRVGKPIIFEKdihVLLPQLVSNE------ 174
Cdd:pfam13580 8 ALLERVVETQADAIEKAADliaaSLANGGKVYAFGTGHSAAPAEEL---FARAGGLAGFEP---ILLPALALHTdasati 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2045666817 175 ---------------------KKKVLWLVSNSGRSADVVALAELAKSMNIEIIALT 209
Cdd:pfam13580 82 stalerdegyarqilalypgrPGDVLIVISNSGINAVPVEAALEAKERGMKVIALT 137
|
|
| SIS_GlmS_GlmD_1 |
cd05008 |
SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and ... |
182-249 |
3.03e-05 |
|
SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal glutaminase domain and two C-terminal SIS domains and catalyzes the first step in hexosamine metabolism, converting fructose 6-phosphate into glucosamine 6-phosphate using glutamine as nitrogen source. The glutaminase domain hydrolyzes glutamine to glutamate and ammonia. Ammonia is transferred through a channel to the isomerase domain for glucosamine 6-phosphate synthesis. The end product of the pathway is N-acetylglucosamine, which plays multiple roles in eukaryotic cells including being a building block of bacterial and fungal cell walls. In the absence of glutamine, GlmS catalyzes the isomerization of fructose 6-phosphate into glucose 6- phosphate (PGI-like activity). Glucosamine-6-phosphate deaminase (GlmD) contains two SIS domains and catalyzes the deamination and isomerization of glucosamine-6-phosphate into fructose-6-phosphate with the release of ammonia; in presence of high ammonia concentration, GlmD can catalyze the reverse reaction.
Pssm-ID: 240141 [Multi-domain] Cd Length: 126 Bit Score: 42.48 E-value: 3.03e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2045666817 182 VSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRPKEITNrsAATNSLLAQFATI 249
Cdd:cd05008 53 ISQSGETADTLAALRLAKEKGAKTVAITNVVGSTLAREADYVLYLRAGPEISV--AATKAFTSQLLAL 118
|
|
| SIS_1 |
cd05710 |
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar ... |
175-234 |
1.53e-04 |
|
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240214 [Multi-domain] Cd Length: 120 Bit Score: 40.64 E-value: 1.53e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 175 KKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSKIADVLVQTSRPKEITN 234
Cdd:cd05710 47 EKSVVILASHSGNTKETVAAAKFAKEKGATVIGLTDDEDSPLAKLADYVIVYGFEIDAVE 106
|
|
| SIS |
cd04795 |
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
131-209 |
1.22e-03 |
|
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240112 [Multi-domain] Cd Length: 87 Bit Score: 37.35 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2045666817 131 VFLYGVGASSLVVEDILQKWSR-VGKPIIFEKDIHVLL-PQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIAL 208
Cdd:cd04795 1 IFVIGIGGSGAIAAYFALELLElTGIEVVALIATELEHaSLLSLLRKGDVVIALSYSGRTEELLAALEIAKELGIPVIAI 80
|
.
gi 2045666817 209 T 209
Cdd:cd04795 81 T 81
|
|
| |
