|
Name |
Accession |
Description |
Interval |
E-value |
| Thr-synth_1 |
cd01563 |
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last ... |
6-320 |
2.90e-151 |
|
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants, OPH is an intermediate between the methionine and threonine/isoleucine pathways. Thus threonine synthase competes for OPH with cystathionine-gamma-synthase, the first enzyme in the methionine pathway. These enzymes are in general dimers. Members of this CD, Thr-synth_1, are widely distributed in bacteria, archaea and higher plants.
Pssm-ID: 107206 [Multi-domain] Cd Length: 324 Bit Score: 428.55 E-value: 2.90e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 6 LKQYASYLPVNENtPDVSLMEGNTPLIPLLNISKQLGIQ-LYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIICASTG 84
Cdd:cd01563 1 LWRYRELLPVTED-DIVSLGEGNTPLVRAPRLGERLGGKnLYVKDEGLNPTGSFKDRGMTVAVSKAKELGVKAVACASTG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 85 NTSASAAAYAARLGMKCIIVIPEGKiAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVNPYRIEGQKT 164
Cdd:cd01563 80 NTSASLAAYAARAGIKCVVFLPAGK-ALGKLAQALAYGATVLAVEGNFDDALRLVRELAEENWIYLSNSLNPYRLEGQKT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 165 AAFEICDQL-QNTPDVLAIPVGNAGNITAYWKGFCEYeKEKGY--KKPRIHGFEAEGAAAIVKG--------HVIEAPET 233
Cdd:cd01563 159 IAFEIAEQLgWEVPDYVVVPVGNGGNITAIWKGFKEL-KELGLidRLPRMVGVQAEGAAPIVRAfkegkddiEPVENPET 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 234 IATAIRIGNPASWSYAVEAAEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSGKIKKGETVVAVL 313
Cdd:cd01563 238 IATAIRIGNPASGPKALRAVRESGGTAVAVSDEEILEAQKLLARTEGIFVEPASAASLAGLKKLREEGIIDKGERVVVVL 317
|
....*..
gi 2049255829 314 TGNGLKD 320
Cdd:cd01563 318 TGHGLKD 324
|
|
| ThrC |
COG0498 |
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the ... |
9-347 |
3.27e-140 |
|
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 440264 [Multi-domain] Cd Length: 394 Bit Score: 403.04 E-value: 3.27e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 9 YASYLPVNENTPDVSLMEGNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIICASTGNTSA 88
Cdd:COG0498 47 YRELLPFDDEEKAVSLGEGGTPLVKAPRLADELGKNLYVKEEGHNPTGSFKDRAMQVAVSLALERGAKTIVCASSGNGSA 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 89 SAAAYAARLGMKCIIVIPEGKIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVNPYRIEGQKTAAFE 168
Cdd:COG0498 127 ALAAYAARAGIEVFVFVPEGKVSPGQLAQMLTYGAHVIAVDGNFDDAQRLVKELAADEGLYAVNSINPARLEGQKTYAFE 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 169 ICDQLQNTPDVLAIPVGNAGNITAYWKGFCEYeKEKGY--KKPRIHGFEAEGAAAIVK-------GHVIEAPETIATAIR 239
Cdd:COG0498 207 IAEQLGRVPDWVVVPTGNGGNILAGYKAFKEL-KELGLidRLPRLIAVQATGCNPILTafetgrdEYEPERPETIAPSMD 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 240 IGNPASWSYAVEAAEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSGKIKKGETVVAVLTGNGLK 319
Cdd:COG0498 286 IGNPSNGERALFALRESGGTAVAVSDEEILEAIRLLARREGIFVEPATAVAVAGLRKLREEGEIDPDEPVVVLSTGHGLK 365
|
330 340
....*....|....*....|....*...
gi 2049255829 320 DPDIAISSNKFDIASVSNDIEQIKEHIK 347
Cdd:COG0498 366 FPDAVREALGGEPLAVPPDLEAVKAAVE 393
|
|
| thrC |
TIGR00260 |
threonine synthase; Involved in threonine biosynthesis it catalyses the reaction ... |
8-322 |
9.15e-132 |
|
threonine synthase; Involved in threonine biosynthesis it catalyses the reaction O-PHOSPHO-L-HOMOSERINE + H(2)O = L-THREONINE + ORTHOPHOSPHATE using pyridoxal phosphate as a cofactor. the enzyme is distantly related to the serine/threonine dehydratases which are also pyridoxal-phosphate dependent enzymes. the pyridoxal-phosphate binding site is a Lys (K) residues present at residue 70 of the model. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 272986 [Multi-domain] Cd Length: 327 Bit Score: 379.03 E-value: 9.15e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 8 QYASYLPVNEnTPDVSLMEGNTPLIPLLNISKQLGI-QLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIICASTGNT 86
Cdd:TIGR00260 3 RYREFLPVTE-KDLVDLGEGVTPLFRAPALAANVGIkNLYVKELGHNPTLSFKDRGMAVALTKALELGNDTVLCASTGNT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 87 SASAAAYAARLGMKCIIVIPEGKIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVN--PYRIEGQKT 164
Cdd:TIGR00260 82 GAAAAAYAGKAGLKVVVLYPAGKISLGKLAQALGYNAEVVAIDGNFDDAQRLVKQLFEDKPALGLNSANsiPYRLEGQKT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 165 AAFEICDQL-QNTPDVLAIPVGNAGNITAYWKGFCEYEKEKGYKKPRIHGFEAEGAAAIVKG-------HVIEAPETIAT 236
Cdd:TIGR00260 162 YAFEAVEQLgWEAPDKVVVPVPNSGNFGAIWKGFKEKKMLGLDSLPVKRGIQAEGAADIVRAfleggqwEPIETPETLST 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 237 AIRIGNPASWSYAVEAAEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSGKIKKGETVVAVLTGN 316
Cdd:TIGR00260 242 AMDIGNPANWPRALEAFRRSNGYAEDLSDEEILEAIKLLAREEGYFVEPHSAVAVAALLKLVEKGTADPAERVVCALTGN 321
|
....*.
gi 2049255829 317 GLKDPD 322
Cdd:TIGR00260 322 GLKDPE 327
|
|
| PALP |
pfam00291 |
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate ... |
22-315 |
1.20e-79 |
|
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Pssm-ID: 459749 [Multi-domain] Cd Length: 295 Bit Score: 245.30 E-value: 1.20e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 22 VSLMEGNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEE-GAEAIICASTGNTSASAAAYAARLGMK 100
Cdd:pfam00291 1 ISLGIGPTPLVRLPRLSKELGVDVYLKLESLNPTGSFKDRGALNLLLRLKEGeGGKTVVEASSGNHGRALAAAAARLGLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 101 CIIVIPEGKIAhGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEP-ITLVNSV-NPYRIEGQKTAAFEICDQLQNTPD 178
Cdd:pfam00291 81 VTIVVPEDAPP-GKLLLMRALGAEVVLVGGDYDEAVAAARELAAEGPgAYYINQYdNPLNIEGYGTIGLEILEQLGGDPD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 179 VLAIPVGNAGNITAYWKGFceyekEKGYKKPRIHGFEAEGAAAIVKGH------VIEAPETIATAIRIGNPASwSYAVEA 252
Cdd:pfam00291 160 AVVVPVGGGGLIAGIARGL-----KELGPDVRVIGVEPEGAPALARSLaagrpvPVPVADTIADGLGVGDEPG-ALALDL 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2049255829 253 AEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGvMKHVQSGKIKKGETVVAVLTG 315
Cdd:pfam00291 234 LDEYVGEVVTVSDEEALEAMRLLARREGIVVEPSSAAALAA-LKLALAGELKGGDRVVVVLTG 295
|
|
| PLN02569 |
PLN02569 |
threonine synthase |
13-351 |
4.16e-71 |
|
threonine synthase
Pssm-ID: 178182 [Multi-domain] Cd Length: 484 Bit Score: 229.32 E-value: 4.16e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 13 LPVNENTPDVSLMEGNTPLIPLLNISKQ-LGIQ-LYGKYEGANPTGSFKDRGMVMAVAKAKEEG-----AEAIICASTGN 85
Cdd:PLN02569 118 LPEIDDDDIVSLFEGNSNLFWAERLGKEfLGMNdLWVKHCGISHTGSFKDLGMTVLVSQVNRLRkmakpVVGVGCASTGD 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 86 TSASAAAYAARLGMKCIIVIPEGKIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVNPYRIEGQKTA 165
Cdd:PLN02569 198 TSAALSAYCAAAGIPSIVFLPADKISIAQLVQPIANGALVLSIDTDFDGCMRLIREVTAELPIYLANSLNSLRLEGQKTA 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 166 AFEICDQLQ-NTPDVLAIPVGNAGNITAYWKGFCEYeKEKGY--KKPRIHGFEAEGAAAIVKGH--------VIEAPETI 234
Cdd:PLN02569 278 AIEILQQFDwEVPDWVIVPGGNLGNIYAFYKGFKMC-KELGLvdRLPRLVCAQAANANPLYRAYksgweefkPVKANPTF 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 235 ATAIRIGNPASWSYAVEAAEQSNGEIDMVSDEEILHAyRLLAKTEGVFAEPGSNASLAGVMKHVQSGKIKKGETVVAVLT 314
Cdd:PLN02569 357 ASAIQIGDPVSIDRAVYALKESNGIVEEATEEELMDA-QAEADKTGMFLCPHTGVALAALKKLRASGVIGPTDRTVVVST 435
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 2049255829 315 GNGLK--DPDIAISSNKF-DIAS-VSNDIEQIKEHIkGVIM 351
Cdd:PLN02569 436 AHGLKftQSKIDYHSKEIpDMACrFANPPVSVKADF-GSVM 475
|
|
| Trp-synth-beta_II |
cd00640 |
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP) ... |
29-315 |
5.95e-69 |
|
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan synthase beta chain (Trp-synth_B), cystathionine beta-synthase (CBS), O-acetylserine sulfhydrylase (CS), serine dehydratase (Ser-dehyd), threonine dehydratase (Thr-dehyd), diaminopropionate ammonia lyase (DAL), and threonine synthase (Thr-synth). ACCD catalyzes the conversion of 1-aminocyclopropane-1-carboxylate to alpha-ketobutyrate and ammonia. Tryptophan synthase folds into a tetramer, where the beta chain is the catalytic PLP-binding subunit and catalyzes the formation of L-tryptophan from indole and L-serine. CBS is a tetrameric hemeprotein that catalyzes condensation of serine and homocysteine to cystathionine. CS is a homodimer that catalyzes the formation of L-cysteine from O-acetyl-L-serine. Ser-dehyd catalyzes the conversion of L- or D-serine to pyruvate and ammonia. Thr-dehyd is active as a homodimer and catalyzes the conversion of L-threonine to 2-oxobutanoate and ammonia. DAL is also a homodimer and catalyzes the alpha, beta-elimination reaction of both L- and D-alpha, beta-diaminopropionate to form pyruvate and ammonia. Thr-synth catalyzes the formation of threonine and inorganic phosphate from O-phosphohomoserine.
Pssm-ID: 107202 [Multi-domain] Cd Length: 244 Bit Score: 216.23 E-value: 5.95e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEA---IICASTGNTSASAAAYAARLGMKCIIVI 105
Cdd:cd00640 1 TPLVRLKRLSKLGGANIYLKLEFLNPTGSFKDRGALNLILLAEEEGKLPkgvIIESTGGNTGIALAAAAARLGLKCTIVM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 106 PEGKiAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEP-ITLVNS-VNPYRIEGQKTAAFEICDQLQN-TPDVLAI 182
Cdd:cd00640 81 PEGA-SPEKVAQMRALGAEVVLVPGDFDDAIALAKELAEEDPgAYYVNQfDNPANIAGQGTIGLEILEQLGGqKPDAVVV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 183 PVGNAGNITAYWKGFCEyekekGYKKPRIHGFEAegaaaivkghvieapetiatairignpaswsyaveaaeqsngEIDM 262
Cdd:cd00640 160 PVGGGGNIAGIARALKE-----LLPNVKVIGVEP------------------------------------------EVVT 192
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 2049255829 263 VSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQsgKIKKGETVVAVLTG 315
Cdd:cd00640 193 VSDEEALEAIRLLAREEGILVEPSSAAALAAALKLAK--KLGKGKTVVVILTG 243
|
|
| PRK08197 |
PRK08197 |
threonine synthase; Validated |
9-322 |
1.52e-60 |
|
threonine synthase; Validated
Pssm-ID: 181283 [Multi-domain] Cd Length: 394 Bit Score: 199.46 E-value: 1.52e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 9 YASYLPVNENTPDVSLMEGNTPLIPLLNISKQLGI-QLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIICASTGNTS 87
Cdd:PRK08197 60 YHELLPVRDPEHIVSLGEGMTPLLPLPRLGKALGIgRLWVKDEGLNPTGSFKARGLAVGVSRAKELGVKHLAMPTNGNAG 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 88 ASAAAYAARLGMKCIIVIPEGKIAHGKLaQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVN-PYRIEGQKTAA 166
Cdd:PRK08197 140 AAWAAYAARAGIRATIFMPADAPEITRL-ECALAGAELYLVDGLISDAGKIVAEAVAEYGWFDVSTLKePYRIEGKKTMG 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 167 FEICDQLQ-NTPDVLAIPVGNAGNITAYWKGFCEYEKEK--GYKKPRIHGFEAEGAAAIVKG---HVIEA-----PETIA 235
Cdd:PRK08197 219 LELAEQLGwRLPDVILYPTGGGVGLIGIWKAFDELEALGwiGGKRPRLVAVQAEGCAPIVKAweeGKEESefwedAHTVA 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 236 TAIRIGNPASWSYAVEAAEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSGKIKKGETVVAVLTG 315
Cdd:PRK08197 299 FGIRVPKALGDFLVLDAVRETGGCAIAVSDDAILAAQRELAREEGLFACPEGAATFAAARQLRESGWLKGDERVVLFNTG 378
|
....*..
gi 2049255829 316 NGLKDPD 322
Cdd:PRK08197 379 SGLKYPD 385
|
|
| PRK05638 |
PRK05638 |
threonine synthase; Validated |
22-342 |
7.31e-51 |
|
threonine synthase; Validated
Pssm-ID: 235539 [Multi-domain] Cd Length: 442 Bit Score: 175.39 E-value: 7.31e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 22 VSLMEGNTPLIPLlNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIICASTGNTSASAAAYAARLGMKC 101
Cdd:PRK05638 60 ISLGEGGTPLIRA-RISEKLGENVYIKDETRNPTGSFRDRLATVAVSYGLPYAANGFIVASDGNAAASVAAYSARAGKEA 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 102 IIVIPEgKIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEpiTLVNSVNPYRI---EGQKTAAFEICDQLqnTPD 178
Cdd:PRK05638 139 FVVVPR-KVDKGKLIQMIAFGAKIIRYGESVDEAIEYAEELARLN--GLYNVTPEYNIiglEGQKTIAFELWEEI--NPT 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 179 VLAIPVGNAGNITAYWKGFCEYEKEKGYKK-PRIHGFEAEGAAAI---VKGHVIEAPETIATAIRIGNPASWSYAVEAAE 254
Cdd:PRK05638 214 HVIVPTGSGSYLYSIYKGFKELLEIGVIEEiPKLIAVQTERCNPIaseILGNKTKCNETKALGLYVKNPVMKEYVSEAIK 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 255 QSNGEIDMVSDEEILHAYRLLAKtEGVFAEPGSNASLAGVMKHVQSGKIKKGETVVAVLTGNGLKDPDiAISSNKFDIAS 334
Cdd:PRK05638 294 ESGGTAVVVNEEEIMAGEKLLAK-EGIFAELSSAVVMPALLKLGEEGYIEKGDKVVLVVTGSGLKGYG-EGGREKFTIGG 371
|
....*...
gi 2049255829 335 VSNDIEQI 342
Cdd:PRK05638 372 TKLEILKI 379
|
|
| IlvA |
COG1171 |
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the ... |
29-315 |
1.96e-42 |
|
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440784 [Multi-domain] Cd Length: 327 Bit Score: 150.19 E-value: 1.96e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEA-IICASTGN---------TsasaaayaaRLG 98
Cdd:COG1171 25 TPLLRSPTLSERLGAEVYLKLENLQPTGSFKLRGAYNALASLSEEERARgVVAASAGNhaqgvayaaR---------LLG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 99 MKCIIVIPEGkIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVNPYR-IEGQKTAAFEICDQLQNtP 177
Cdd:COG1171 96 IPATIVMPET-APAVKVAATRAYGAEVVLHGDTYDDAEAAAAELAEEEGATFVHPFDDPDvIAGQGTIALEILEQLPD-L 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 178 DVLAIPVGN----AGnITAYWKGFCeyekekgyKKPRIHGFEAEGAA----AIVKGHVIEAPE--TIATAIRIGNPASWS 247
Cdd:COG1171 174 DAVFVPVGGggliAG-VAAALKALS--------PDIRVIGVEPEGAAamyrSLAAGEPVTLPGvdTIADGLAVGRPGELT 244
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2049255829 248 YAVeaAEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMkhvqSGKIK-KGETVVAVLTG 315
Cdd:COG1171 245 FEI--LRDLVDDIVTVSEDEIAAAMRLLLERTKIVVEPAGAAALAALL----AGKERlKGKRVVVVLSG 307
|
|
| PRK08329 |
PRK08329 |
threonine synthase; Validated |
6-319 |
8.79e-41 |
|
threonine synthase; Validated
Pssm-ID: 236244 [Multi-domain] Cd Length: 347 Bit Score: 146.12 E-value: 8.79e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 6 LKQYASYLPVNEN-TPdvslmegntPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIICASTG 84
Cdd:PRK08329 43 MRRYIDYLPVDEEfLP---------HLTPPITPTVKRSIKVYFKLDYLQPTGSFKDRGTYVTVAKLKEEGINEVVIDSSG 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 85 NTSASAAAYAARLGMKCIIVIPEgKIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNS-VNPYRIEGQK 163
Cdd:PRK08329 114 NAALSLALYSLSEGIKVHVFVSY-NASKEKISLLSRLGAELHFVEGDRMEVHEEAVKFSKRNNIPYVSHwLNPYFLEGTK 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 164 TAAFEICDQLQNtPDVLAIPVGNAGNITAYWKGFCE-YEKEKGYKKPRIHGFEAEGAAAIVKGHVIEapETIATAIRIGN 242
Cdd:PRK08329 193 TIAYEIYEQIGV-PDYAFVPVGSGTLFLGIWKGFKElHEMGEISKMPKLVAVQAEGYESLCKRSKSE--NKLADGIAIPE 269
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2049255829 243 PASWSYAVEAAEQSNGEIDMVSDEEILHAYRLLAKTeGVFAEPGSNASLAGVMKHVQSGKIKKGETVVAVLTGNGLK 319
Cdd:PRK08329 270 PPRKEEMLRALEESNGFCISVGEEETRAALHWLRRM-GFLVEPTSAVALAAYWKLLEEGLIEGGSKVLLPLSGSGLK 345
|
|
| PRK06381 |
PRK06381 |
threonine synthase; Validated |
27-315 |
1.20e-40 |
|
threonine synthase; Validated
Pssm-ID: 235789 Cd Length: 319 Bit Score: 145.23 E-value: 1.20e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 27 GNTPLIPLLNISKQLGI-QLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIICASTGNTSASAAAYAARLGMKCIIVI 105
Cdd:PRK06381 14 GGTPLLRARKLEEELGLrKIYLKFEGANPTGTQKDRIAEAHVRRAMRLGYSGITVGTCGNYGASIAYFARLYGLKAVIFI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 106 PEGkIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVN--SVNP-YRIEGQKTAAFEICDQLQNTPDVLAI 182
Cdd:PRK06381 94 PRS-YSNSRVKEMEKYGAEIIYVDGKYEEAVERSRKFAKENGIYDANpgSVNSvVDIEAYSAIAYEIYEALGDVPDAVAV 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 183 PVGNAGNITAYWKGFCE-YEKEKGYKKPRIHGFEAEGAAAIVKGH-------VIEAPETIA-TAIRIGNPASWSY----A 249
Cdd:PRK06381 173 PVGNGTTLAGIYHGFRRlYDRGKTSRMPRMIGVSTSGGNQIVESFkrgssevVDLEVDEIReTAVNEPLVSYRSFdgdnA 252
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2049255829 250 VEAAEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSGKIKkgETVVAVLTG 315
Cdd:PRK06381 253 LEAIYDSHGYAFGFSDDEMVKYAELLRRMEGLNALPASASALAALVKYLKKNGVN--DNVVAVITG 316
|
|
| Thr-dehyd |
cd01562 |
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. ... |
29-315 |
3.14e-40 |
|
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.
Pssm-ID: 107205 [Multi-domain] Cd Length: 304 Bit Score: 143.78 E-value: 3.14e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEA-IICASTGNTSASAAAYAARLGMKCIIVIPE 107
Cdd:cd01562 18 TPLLTSPTLSELLGAEVYLKCENLQKTGSFKIRGAYNKLLSLSEEERAKgVVAASAGNHAQGVAYAAKLLGIPATIVMPE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 108 GKIAHgKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVN-PYRIEGQKTAAFEICDQLQNtPDVLAIPVGN 186
Cdd:cd01562 98 TAPAA-KVDATRAYGAEVVLYGEDFDEAEAKARELAEEEGLTFIHPFDdPDVIAGQGTIGLEILEQVPD-LDAVFVPVGG 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 187 AG---NITAYWKGFceyekekgykKP--RIHGFEAEGAAA----IVKGHVIEAPE--TIATAIRIGNPASWSYAVeaAEQ 255
Cdd:cd01562 176 GGliaGIATAVKAL----------SPntKVIGVEPEGAPAmaqsLAAGKPVTLPEvdTIADGLAVKRPGELTFEI--IRK 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2049255829 256 SNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMkhvqSGKIK-KGETVVAVLTG 315
Cdd:cd01562 244 LVDDVVTVSEDEIAAAMLLLFEREKLVAEPAGALALAALL----SGKLDlKGKKVVVVLSG 300
|
|
| CBS_like |
cd01561 |
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS ... |
27-313 |
4.37e-31 |
|
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.
Pssm-ID: 107204 [Multi-domain] Cd Length: 291 Bit Score: 118.77 E-value: 4.37e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 27 GNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGA----EAIICASTGNTSASAAAYAARLGMKCI 102
Cdd:cd01561 1 GNTPLVRLNRLSPGTGAEIYAKLEFFNPGGSVKDRIALYMIEDAEKRGLlkpgTTIIEPTSGNTGIGLAMVAAAKGYRFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 103 IVIPEgKIAHGKLAQAVAYGAEIISIEGNFDD----ALRAVRNIAAEEPitlvNSV------NPYRIEG-QKTAAFEICD 171
Cdd:cd01561 81 IVMPE-TMSEEKRKLLRALGAEVILTPEAEADgmkgAIAKARELAAETP----NAFwlnqfeNPANPEAhYETTAPEIWE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 172 QLQNTPDVLAIPVGNAGNITaywkGFCEYEKEKgYKKPRIHGFEAEGAAAIVKGHvieAPETIATAIRIGN-PASWSYAV 250
Cdd:cd01561 156 QLDGKVDAFVAGVGTGGTIT----GVARYLKEK-NPNVRIVGVDPVGSVLFSGGP---PGPHKIEGIGAGFiPENLDRSL 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2049255829 251 eaaeqsngeIDM---VSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHvqSGKIKKGETVVAVL 313
Cdd:cd01561 228 ---------IDEvvrVSDEEAFAMARRLAREEGLLVGGSSGAAVAAALKL--AKRLGPGKTIVTIL 282
|
|
| PRK06450 |
PRK06450 |
threonine synthase; Validated |
22-319 |
2.91e-29 |
|
threonine synthase; Validated
Pssm-ID: 180565 [Multi-domain] Cd Length: 338 Bit Score: 115.22 E-value: 2.91e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 22 VSLMEGNTPLIPLLNIskqlgiqlYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIICASTGNTSASAAAYAARLGMKC 101
Cdd:PRK06450 52 ISLGEGRTPLIKKGNI--------WFKLDFLNPTGSYKDRGSVTLISYLAEKGIKQISEDSSGNAGASIAAYGAAAGIEV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 102 IIVIPEgKIAHGKLAQAVAYGAEIISIEGNFDDALRAvrniAAEEPITLVNSV-NPYRIEGQKTAAFEICDQLQ-NTPDV 179
Cdd:PRK06450 124 KIFVPE-TASGGKLKQIESYGAEVVRVRGSREDVAKA----AENSGYYYASHVlQPQFRDGIRTLAYEIAKDLDwKIPNY 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 180 LAIPVGNAGNITAYWKGFcEYEKEKGY--KKPRIHGFEAEGAA---AIVKGHVIEAPE---TIATAIRIGNPASWSYAVE 251
Cdd:PRK06450 199 VFIPVSAGTLLLGVYSGF-KHLLDSGVisEMPKIVAVQTEQVSplcAKFKGISYTPPDkvtSIADALVSTRPFLLDYMVK 277
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2049255829 252 AAeQSNGEIDMVSDEEILHAYRLLAKtEGVFAEPGSNASLAGvmkhvqsGKIKKGETVVAVLTGNGLK 319
Cdd:PRK06450 278 AL-SEYGECIVVSDNEIVEAWKELAK-KGLLVEYSSATVYAA-------YKKYSVNDSVLVLTGSGLK 336
|
|
| CysK |
COG0031 |
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the ... |
27-319 |
2.96e-29 |
|
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the Pathway/BioSystem: Cysteine biosynthesis
Pssm-ID: 439802 [Multi-domain] Cd Length: 301 Bit Score: 114.38 E-value: 2.96e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 27 GNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDR---GMVMAvakAKEEGA----EAIICASTGNTSASAAAYAARLGM 99
Cdd:COG0031 12 GNTPLVRLNRLSPGPGAEIYAKLESFNPGGSVKDRialSMIED---AEKRGLlkpgGTIVEATSGNTGIGLAMVAAAKGY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 100 KCIIVIPEG----KIAHGKlaqavAYGAEIISIEG--NFDDALRAVRNIAAEEPitlvNSV------NPYRIEG-QKTAA 166
Cdd:COG0031 89 RLILVMPETmskeRRALLR-----AYGAEVVLTPGaeGMKGAIDKAEELAAETP----GAFwpnqfeNPANPEAhYETTG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 167 FEICDQLQNTPDVLAIPVGNAGNITaywkGFCEYEKEKGyKKPRIHGFEAEGAAAIVKG----HVIEapetiataiRIGN 242
Cdd:COG0031 160 PEIWEQTDGKVDAFVAGVGTGGTIT----GVGRYLKERN-PDIKIVAVEPEGSPLLSGGepgpHKIE---------GIGA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 243 ---PASWSYAVeaaeqsngeID---MVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQsgKIKKGETVVAVLTGN 316
Cdd:COG0031 226 gfvPKILDPSL---------IDeviTVSDEEAFAMARRLAREEGILVGISSGAAVAAALRLAK--RLGPGKTIVTILPDS 294
|
...
gi 2049255829 317 GLK 319
Cdd:COG0031 295 GER 297
|
|
| L-Ser-dehyd |
cd06448 |
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the ... |
28-305 |
1.45e-22 |
|
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- , D-serine, or L-threonine to pyruvate/ketobutyrate and ammonia.
Pssm-ID: 107209 Cd Length: 316 Bit Score: 96.21 E-value: 1.45e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 28 NTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGM---VMAVAKAKEEGAEAIICASTGNTSASAAAYAARLGMKCIIV 104
Cdd:cd06448 1 KTPLIESTALSKTAGCNVFLKLENLQPSGSFKIRGIghlCQKSAKQGLNECVHVVCSSGGNAGLAAAYAARKLGVPCTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 105 IPE--GKIAHGKLAQavaYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSV---NPYRIEGQKTAAFEICDQLQN--TP 177
Cdd:cd06448 81 VPEstKPRVVEKLRD---EGATVVVHGKVWWEADNYLREELAENDPGPVYVHpfdDPLIWEGHSSMVDEIAQQLQSqeKV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 178 DVLAIPVGNAGNITAYWKGFceyeKEKGYKKPRIHGFEAEGA----AAIVKGHVIEAPETIATAIRIGNPASWSYAVEAA 253
Cdd:cd06448 158 DAIVCSVGGGGLLNGIVQGL----ERNGWGDIPVVAVETEGAhslnASLKAGKLVTLPKITSVATSLGAKTVSSQALEYA 233
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 2049255829 254 EQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMkhvqSGKIKK 305
Cdd:cd06448 234 QEHNIKSEVVSDRDAVQACLRFADDERILVEPACGAALAVVY----SGKILD 281
|
|
| PRK08638 |
PRK08638 |
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB; |
29-315 |
1.19e-20 |
|
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB;
Pssm-ID: 236317 [Multi-domain] Cd Length: 333 Bit Score: 91.34 E-value: 1.19e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAK-AKEEGAEAIICASTGNTSASAAAYAARLGMKCIIVIPE 107
Cdd:PRK08638 28 TPLPRSNYLSERCKGEIFLKLENMQRTGSFKIRGAFNKLSSlTDAEKRKGVVACSAGNHAQGVALSCALLGIDGKVVMPK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 108 GKiAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVN-PYRIEGQKTAAFEICDQLQNTPDVLaIPVGN 186
Cdd:PRK08638 108 GA-PKSKVAATCGYGAEVVLHGDNFNDTIAKVEEIVEEEGRTFIPPYDdPKVIAGQGTIGLEILEDLWDVDTVI-VPIGG 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 187 AGNITAY---WKGFCEYEKEKGYKKPRIHGFeaegAAAIVKGHVIEAPE--TIATAIRIGNPASWSYAVeaAEQSNGEID 261
Cdd:PRK08638 186 GGLIAGIavaLKSINPTIHIIGVQSENVHGM----AASFYAGEITTHRTtgTLADGCDVSRPGNLTYEI--VRELVDDIV 259
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2049255829 262 MVSDEEILHAYRLLAKTEGVFAE-PGSNASLAgvmkhVQSGKIK---KGETVVAVLTG 315
Cdd:PRK08638 260 LVSEDEIRNAMKDLIQRNKVVTEgAGALATAA-----LLSGKLDqyiQNKKVVAIISG 312
|
|
| PRK06815 |
PRK06815 |
threonine/serine dehydratase; |
29-315 |
1.66e-20 |
|
threonine/serine dehydratase;
Pssm-ID: 180709 [Multi-domain] Cd Length: 317 Bit Score: 90.52 E-value: 1.66e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRG----MVMAVAKAKEEGaeaIICASTGNTSASAAAYAARLGMKCIIV 104
Cdd:PRK06815 21 TPLEHSPLLSQHTGCEVYLKCEHLQHTGSFKFRGasnkLRLLNEAQRQQG---VITASSGNHGQGVALAAKLAGIPVTVY 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 105 IPEGkIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVN-PYRIEGQKTAAFEICDQLQNtPDVLAIP 183
Cdd:PRK06815 98 APEQ-ASAIKLDAIRALGAEVRLYGGDALNAELAARRAAEQQGKVYISPYNdPQVIAGQGTIGMELVEQQPD-LDAVFVA 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 184 VGNAGNITaywkGFCEYEKEKGyKKPRIHGFEAEGAAA----IVKGHVIEAPE--TIA--TAiriGNPASWSYAVEAAEQ 255
Cdd:PRK06815 176 VGGGGLIS----GIATYLKTLS-PKTEIIGCWPANSPSlytsLEAGEIVEVAEqpTLSdgTA---GGVEPGAITFPLCQQ 247
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 256 SNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKhvqSGKIKKGETVVAVLTG 315
Cdd:PRK06815 248 LIDQKVLVSEEEIKEAMRLIAETDRWLIEGAAGVALAAALK---LAPRYQGKKVAVVLCG 304
|
|
| PRK12483 |
PRK12483 |
threonine dehydratase; Reviewed |
29-315 |
1.04e-19 |
|
threonine dehydratase; Reviewed
Pssm-ID: 237111 [Multi-domain] Cd Length: 521 Bit Score: 89.86 E-value: 1.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAK-AKEEGAEAIICASTGNTSASAAAYAARLGMKCIIVIPE 107
Cdd:PRK12483 38 TPLQRAPNLSARLGNQVLLKREDLQPVFSFKIRGAYNKMARlPAEQLARGVITASAGNHAQGVALAAARLGVKAVIVMPR 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 108 gKIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSV-NPYRIEGQKTAAFEICDQLQNTPDVLAIPVGN 186
Cdd:PRK12483 118 -TTPQLKVDGVRAHGGEVVLHGESFPDALAHALKLAEEEGLTFVPPFdDPDVIAGQGTVAMEILRQHPGPLDAIFVPVGG 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 187 AGNITaywkGFCEYEKekgYKKP--RIHGFEAEG----AAAIVKGHVIEAPE--TIATAIRIGNPASWSYAVEAAEQSng 258
Cdd:PRK12483 197 GGLIA----GIAAYVK---YVRPeiKVIGVEPDDsnclQAALAAGERVVLGQvgLFADGVAVAQIGEHTFELCRHYVD-- 267
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2049255829 259 EIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSGKIkKGETVVAVLTG 315
Cdd:PRK12483 268 EVVTVSTDELCAAIKDIYDDTRSITEPAGALAVAGIKKYAEREGI-EGQTLVAIDSG 323
|
|
| PRK07334 |
PRK07334 |
threonine dehydratase; Provisional |
28-315 |
3.60e-19 |
|
threonine dehydratase; Provisional
Pssm-ID: 235994 [Multi-domain] Cd Length: 403 Bit Score: 87.64 E-value: 3.60e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 28 NTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAK-AKEEGAEAIICASTGNTSASAAAYAARLGMKCIIVIP 106
Cdd:PRK07334 23 RTPCVHSRTLSQITGAEVWLKFENLQFTASFKERGALNKLLLlTEEERARGVIAMSAGNHAQGVAYHAQRLGIPATIVMP 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 107 EGKIAhGKLAQAVAYGAEIIsIEG-NFDDALRAVRNIAAEEPITLVNSVN-PYRIEGQKTAAFEIcdqLQNTP--DVLAI 182
Cdd:PRK07334 103 RFTPT-VKVERTRGFGAEVV-LHGeTLDEARAHARELAEEEGLTFVHPYDdPAVIAGQGTVALEM---LEDAPdlDTLVV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 183 PVGNAGNI----TAywkgfceyekEKGYKKP-RIHGFEAEG----AAAIVKGHVIEAPETIATAIRIGNPASWSYAVeaA 253
Cdd:PRK07334 178 PIGGGGLIsgmaTA----------AKALKPDiEIIGVQTELypsmYAAIKGVALPCGGSTIAEGIAVKQPGQLTLEI--V 245
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2049255829 254 EQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSGKIKKgetVVAVLTG 315
Cdd:PRK07334 246 RRLVDDILLVSEADIEQAVSLLLEIEKTVVEGAGAAGLAALLAYPERFRGRK---VGLVLSG 304
|
|
| cysKM |
TIGR01136 |
cysteine synthase; This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and ... |
27-317 |
2.87e-18 |
|
cysteine synthase; This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family]
Pssm-ID: 273463 Cd Length: 299 Bit Score: 83.87 E-value: 2.87e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 27 GNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDR---GMVM-AVAKAKEEGAEAIICASTGNTSASAAAYAARLGMKCI 102
Cdd:TIGR01136 6 GNTPLVRLNRLAPGCDARVLAKLEGFNPSGSVKDRialSMILdAEKRGLLKPGDTIIEATSGNTGIALAMVAAARGYKLI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 103 IVIPEGKIAHGKLAQAvAYGAEII--SIEGNFDDALRAVRNIAAEEPITLV-----NSVNPYriEGQKTAAFEICDQLQN 175
Cdd:TIGR01136 86 LTMPETMSLERRKLLR-AYGAELIltPGEEGMKGAIDKAEELAAETNKYVMldqfeNPANPE--AHYKTTGPEIWRDTDG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 176 TPDVLAIPVGNAGNITaywkGFCEYEKEKgYKKPRIHGFEAEGAAAIVKGhvieapETIATAIRiGNPASWSYAVEAAEQ 255
Cdd:TIGR01136 163 RIDHFVAGVGTGGTIT----GVGRYLKEQ-NPNIQIVAVEPAESPVLSGG------EPGPHKIQ-GIGAGFIPKILDLSL 230
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2049255829 256 SNgEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKhVQSGKIKKGETVVAVLTGNG 317
Cdd:TIGR01136 231 ID-EVITVSDEDAIETARRLAREEGILVGISSGAAVAAALK-LAKRLENADKVIVAILPDTG 290
|
|
| PRK09224 |
PRK09224 |
threonine ammonia-lyase IlvA; |
29-315 |
5.70e-18 |
|
threonine ammonia-lyase IlvA;
Pssm-ID: 236417 [Multi-domain] Cd Length: 504 Bit Score: 84.80 E-value: 5.70e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGmvmAVAK----AKEEGAEAIICASTGNTSASAAAYAARLGMKCIIV 104
Cdd:PRK09224 21 TPLEKAPKLSARLGNQVLLKREDLQPVFSFKLRG---AYNKmaqlTEEQLARGVITASAGNHAQGVALSAARLGIKAVIV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 105 IPEG----KIahgklaQAV-AYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVN-PYRIEGQKTAAFEICDQLQNTPD 178
Cdd:PRK09224 98 MPVTtpdiKV------DAVrAFGGEVVLHGDSFDEAYAHAIELAEEEGLTFIHPFDdPDVIAGQGTIAMEILQQHPHPLD 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 179 VLAIPVGNAG---NITAYWKgfceyekekgYKKP--RIHGFEAEGAAAIVK----GHVIEAPET------IATAiRIGNp 243
Cdd:PRK09224 172 AVFVPVGGGGliaGVAAYIK----------QLRPeiKVIGVEPEDSACLKAaleaGERVDLPQVglfadgVAVK-RIGE- 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2049255829 244 aswsYAVEAAEQSNGEIDMVSDEEIlhayrlLAKTEGVF------AEPGSNASLAGVMKHVQSGKIkKGETVVAVLTG 315
Cdd:PRK09224 240 ----ETFRLCQEYVDDVITVDTDEI------CAAIKDVFedtrsiAEPAGALALAGLKKYVAQHGI-EGETLVAILSG 306
|
|
| PRK06110 |
PRK06110 |
threonine dehydratase; |
33-315 |
1.70e-17 |
|
threonine dehydratase;
Pssm-ID: 235699 Cd Length: 322 Bit Score: 81.96 E-value: 1.70e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 33 PLLniSKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEA--IICASTGNTSASAAAYAARLGMKCIIVIPEGKi 110
Cdd:PRK06110 28 PLL--AERLGCEVWVKHENHTPTGAFKVRGGLVYFDRLARRGPRVrgVISATRGNHGQSVAFAARRHGLAATIVVPHGN- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 111 AHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVNPYRIEGQKTAAFEICDQLQNTpDVLAIPVGNAGNI 190
Cdd:PRK06110 105 SVEKNAAMRALGAELIEHGEDFQAAREEAARLAAERGLHMVPSFHPDLVRGVATYALELFRAVPDL-DVVYVPIGMGSGI 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 191 TAywkgfCEYEKEKGYKKPRIHGFEAEGAAA----IVKGHVIEAP--ETIA--TAIRIGNPASWSYAVEAAEqsngEIDM 262
Cdd:PRK06110 184 CG-----AIAARDALGLKTRIVGVVSAHAPAyalsFEAGRVVTTPvaTTLAdgMACRTPDPEALEVIRAGAD----RIVR 254
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 2049255829 263 VSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKhvQSGKIkKGETVVAVLTG 315
Cdd:PRK06110 255 VTDDEVAAAMRAYFTDTHNVAEGAGAAALAAALQ--ERERL-AGKRVGLVLSG 304
|
|
| PRK08246 |
PRK08246 |
serine/threonine dehydratase; |
55-315 |
2.89e-17 |
|
serine/threonine dehydratase;
Pssm-ID: 181319 [Multi-domain] Cd Length: 310 Bit Score: 81.15 E-value: 2.89e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 55 TGSFKDRGMVMAVAkAKEEGAEAIICASTGNTSASAAAYAARLGMKCIIVIPEgkIA-HGKLAQAVAYGAEIISIEGNFD 133
Cdd:PRK08246 49 TGSFKARGAFNRLL-AAPVPAAGVVAASGGNAGLAVAYAAAALGVPATVFVPE--TApPAKVARLRALGAEVVVVGAEYA 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 134 DALRAVRNIAAEEPITLVNSVN-PYRIEGQKTAAFEICDQLQNtPDVLAIPVGNAG---NITAYWKGfceyekekgykKP 209
Cdd:PRK08246 126 DALEAAQAFAAETGALLCHAYDqPEVLAGAGTLGLEIEEQAPG-VDTVLVAVGGGGliaGIAAWFEG-----------RA 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 210 RIHGFEAEGA----AAIVKGHVIEAP-ETIAT----AIRIGnpaswSYAVEAAEQSNGEIDMVSDEEILHAYRLLAKTEG 280
Cdd:PRK08246 194 RVVAVEPEGAptlhAALAAGEPVDVPvSGIAAdslgARRVG-----EIAFALARAHVVTSVLVSDEAIIAARRALWEELR 268
|
250 260 270
....*....|....*....|....*....|....*..
gi 2049255829 281 VFAEPGSNASLAGVMkhvqSGKIK--KGETVVAVLTG 315
Cdd:PRK08246 269 LAVEPGAATALAALL----SGAYVpaPGERVAVVLCG 301
|
|
| PRK08639 |
PRK08639 |
threonine dehydratase; Validated |
29-315 |
6.40e-17 |
|
threonine dehydratase; Validated
Pssm-ID: 236318 [Multi-domain] Cd Length: 420 Bit Score: 81.39 E-value: 6.40e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAK-AKEEGAEAIICASTGNTSASAAAYAARLGMKCIIVIPe 107
Cdd:PRK08639 26 TPLQRNDYLSEKYGANVYLKREDLQPVRSYKLRGAYNAISQlSDEELAAGVVCASAGNHAQGVAYACRHLGIPGVIFMP- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 108 GKIAHGKLAQAVAYGAEIISI--EG-NFDDALRAVRNIAAEEPITLVNSV-NPYRIEGQKTAAFEICDQLQ--NTPDVLA 181
Cdd:PRK08639 105 VTTPQQKIDQVRFFGGEFVEIvlVGdTFDDSAAAAQEYAEETGATFIPPFdDPDVIAGQGTVAVEILEQLEkeGSPDYVF 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 182 IPVGNAGNITaywkGFCEYEKEKGyKKPRIHGFEAEGA----AAIVKGHVIEAPET------IATAiRIGNpaswsYAVE 251
Cdd:PRK08639 185 VPVGGGGLIS----GVTTYLKERS-PKTKIIGVEPAGAasmkAALEAGKPVTLEKIdkfvdgAAVA-RVGD-----LTFE 253
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2049255829 252 AAEQSNGEIDMVSD----EEILHAYrllaKTEGVFAEPG---SNASLAGVMKHVqsgkikKGETVVAVLTG 315
Cdd:PRK08639 254 ILKDVVDDVVLVPEgavcTTILELY----NKEGIVAEPAgalSIAALELYKDEI------KGKTVVCVISG 314
|
|
| PRK08813 |
PRK08813 |
threonine dehydratase; Provisional |
35-318 |
3.03e-15 |
|
threonine dehydratase; Provisional
Pssm-ID: 236339 [Multi-domain] Cd Length: 349 Bit Score: 75.82 E-value: 3.03e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 35 LNISKQLGIQLygKYEGANPTGSFKDRGMVMAVAKAKEEGAE-AIICASTGNTSASAAAYAARLGMKCIIVIPEGKiAHG 113
Cdd:PRK08813 42 LHYAERFGVWL--KLENLQRTGSYKVRGALNALLAGLERGDErPVICASAGNHAQGVAWSAYRLGVQAITVMPHGA-PQT 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 114 KLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSV-NPYRIEGQKTAAFEICdqlQNTPDVLAIPVGNAGNITa 192
Cdd:PRK08813 119 KIAGVAHWGATVRQHGNSYDEAYAFARELADQNGYRFLSAFdDPDVIAGQGTVGIELA---AHAPDVVIVPIGGGGLAS- 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 193 ywkGFCEYEKEKGYkkpRIHGFEAEGAAAI---VKGHV--IEAPETIATAIRIGNPASWSYAVEAAEQSngEIDMVSDEE 267
Cdd:PRK08813 195 ---GVALALKSQGV---RVVGAQVEGVDSMaraIRGDLreIAPVATLADGVKVKIPGFLTRRLCSSLLD--DVVIVREAE 266
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 2049255829 268 ILHAYRLLAKTEGVFAEPGSNASLAgvmkhvqSGKIKKGETVVAVLTGNGL 318
Cdd:PRK08813 267 LRETLVRLALEEHVIAEGAGALALA-------AGRRVSGKRKCAVVSGGNI 310
|
|
| PLN02550 |
PLN02550 |
threonine dehydratase |
29-195 |
1.93e-13 |
|
threonine dehydratase
Pssm-ID: 178165 [Multi-domain] Cd Length: 591 Bit Score: 71.11 E-value: 1.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAK-AKEEGAEAIICASTGNTSASAAAYAARLGMKCIIVIPE 107
Cdd:PLN02550 110 SPLQLAKKLSERLGVKVLLKREDLQPVFSFKLRGAYNMMAKlPKEQLDKGVICSSAGNHAQGVALSAQRLGCDAVIAMPV 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 108 gKIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSV-NPYRIEGQKTAAFEICDQLQNTPDVLAIPVGN 186
Cdd:PLN02550 190 -TTPEIKWQSVERLGATVVLVGDSYDEAQAYAKQRALEEGRTFIPPFdHPDVIAGQGTVGMEIVRQHQGPLHAIFVPVGG 268
|
170
....*....|..
gi 2049255829 187 AG---NITAYWK 195
Cdd:PLN02550 269 GGliaGIAAYVK 280
|
|
| eutB |
PRK07476 |
threonine dehydratase; Provisional |
29-188 |
3.74e-13 |
|
threonine dehydratase; Provisional
Pssm-ID: 236025 [Multi-domain] Cd Length: 322 Bit Score: 69.22 E-value: 3.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAK-AKEEGAEAIICASTGNTSASAAAYAARLGMKCII---- 103
Cdd:PRK07476 20 TPLVASASLSARAGVPVWLKLETLQPTGSFKLRGATNALLSlSAQERARGVVTASTGNHGRALAYAARALGIRATIcmsr 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 104 VIPEGKIAhgklaqAV-AYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSV-NPYRIEGQKTAAFEICDQLqntPDVLA 181
Cdd:PRK07476 100 LVPANKVD------AIrALGAEVRIVGRSQDDAQAEVERLVREEGLTMVPPFdDPRIIAGQGTIGLEILEAL---PDVAT 170
|
....*..
gi 2049255829 182 IPVGNAG 188
Cdd:PRK07476 171 VLVPLSG 177
|
|
| PRK07048 |
PRK07048 |
threo-3-hydroxy-L-aspartate ammonia-lyase; |
29-305 |
5.81e-13 |
|
threo-3-hydroxy-L-aspartate ammonia-lyase;
Pssm-ID: 235918 [Multi-domain] Cd Length: 321 Bit Score: 68.89 E-value: 5.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEA-IICASTGNTSASAAAYAARLGMKCIIVIPE 107
Cdd:PRK07048 25 TPVLTSRTADARTGAQVFFKCENFQRMGAFKFRGAYNALSQFSPEQRRAgVVTFSSGNHAQAIALSARLLGIPATIVMPQ 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 108 GKIAhGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVN-PYRIEGQKTAAFEICDQLQNTpDVLAIPVGN 186
Cdd:PRK07048 105 DAPA-AKVAATRGYGGEVVTYDRYTEDREEIGRRLAEERGLTLIPPYDhPHVIAGQGTAAKELFEEVGPL-DALFVCLGG 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 187 AGNITAywkgfCEYEKEKGYKKPRIHGFEAE----GAAAIVKGHV--IEAPETIATAIRIGNPASWSYAVeaAEQSNGEI 260
Cdd:PRK07048 183 GGLLSG-----CALAARALSPGCKVYGVEPEagndGQQSFRSGEIvhIDTPRTIADGAQTQHLGNYTFPI--IRRLVDDI 255
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 2049255829 261 DMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSGKIKK 305
Cdd:PRK07048 256 VTVSDAELVDAMRFFAERMKIVVEPTGCLGAAAALRGKVPLKGKR 300
|
|
| PRK06608 |
PRK06608 |
serine/threonine dehydratase; |
29-188 |
1.94e-12 |
|
serine/threonine dehydratase;
Pssm-ID: 235842 [Multi-domain] Cd Length: 338 Bit Score: 67.49 E-value: 1.94e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLI--PLLNisKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEG--AEAIICASTGNTSASAAAYAARLGMKCIIV 104
Cdd:PRK06608 24 TPIVhsESLN--EMLGHEIFFKVESLQKTGAFKVRGVLNHLLELKEQGklPDKIVAYSTGNHGQAVAYASKLFGIKTRIY 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 105 IPEgKIAHGKLAQAVAYGAEIIsiegnfddaLRAVRNIA------AEEPITLVnsVNPYR----IEGQKTAAFEICDQLQ 174
Cdd:PRK06608 102 LPL-NTSKVKQQAALYYGGEVI---------LTNTRQEAeekakeDEEQGFYY--IHPSDsdstIAGAGTLCYEALQQLG 169
|
170
....*....|....
gi 2049255829 175 NTPDVLAIPVGNAG 188
Cdd:PRK06608 170 FSPDAIFASCGGGG 183
|
|
| PLN02970 |
PLN02970 |
serine racemase |
29-317 |
3.65e-12 |
|
serine racemase
Pssm-ID: 215524 [Multi-domain] Cd Length: 328 Bit Score: 66.24 E-value: 3.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAE-AIICASTGNTSASAAAYAARLGMKCIIVIPE 107
Cdd:PLN02970 28 TPVLTSSSLDALAGRSLFFKCECFQKGGAFKFRGACNAIFSLSDDQAEkGVVTHSSGNHAAALALAAKLRGIPAYIVVPK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 108 GKIAhGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSVN-PYRIEGQKTAAFEICDQLQNTpDVLAIPVGN 186
Cdd:PLN02970 108 NAPA-CKVDAVIRYGGIITWCEPTVESREAVAARVQQETGAVLIHPYNdGRVISGQGTIALEFLEQVPEL-DVIIVPISG 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 187 AGNITaywkGFCEYEKEkgyKKPRIHGFEAEGAAA------IVKGHVI--EAPETIATAIR--IGnPASWSYAVEAAEQs 256
Cdd:PLN02970 186 GGLIS----GIALAAKA---IKPSIKIIAAEPKGAddaaqsKAAGEIItlPVTNTIADGLRasLG-DLTWPVVRDLVDD- 256
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2049255829 257 ngeIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVM-KHVQSGKIKKGETVVAVLTGNG 317
Cdd:PLN02970 257 ---VITVDDKEIIEAMKLCYERLKVVVEPSGAIGLAAALsDSFRSNPAWKGCKNVGIVLSGG 315
|
|
| Thr-synth_2 |
cd01560 |
Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of ... |
54-192 |
5.69e-12 |
|
Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants, cyanobacteria, archaebacteria and eubacterial groups. This CD, Thr-synth_2, includes enzymes from fungi and eubacterial groups, as well as, metazoan threonine synthase-like proteins.
Pssm-ID: 107203 [Multi-domain] Cd Length: 460 Bit Score: 66.49 E-value: 5.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 54 PTGSFKDRGM-VMA-----VAKAKEEGAeAIICASTGNTSASAAAYAARL-GMKCIIVIPEGKIAHGKLAQAVAYGAE-- 124
Cdd:cd01560 106 PTLAFKDMALqFLGrlleyFLKRRNERI-TILVATSGDTGSAAIEGFRGKpNVDVVVLYPKGGVSPIQELQMTTLPADnv 184
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2049255829 125 -IISIEGNFDDALRAVRNIAAEEP------ITLVNSVNPYRIEGQKT----AAFEICDQLQNTPDVLAIPVGNAGNITA 192
Cdd:cd01560 185 hVVAVEGDFDDCQSLVKALFADEDfnkklkLSSANSINWARILAQIVyyfyAYLQLLKRGEGEKVEFSVPTGNFGNILA 263
|
|
| PRK10717 |
PRK10717 |
cysteine synthase A; Provisional |
20-313 |
2.87e-11 |
|
cysteine synthase A; Provisional
Pssm-ID: 182672 [Multi-domain] Cd Length: 330 Bit Score: 63.73 E-value: 2.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 20 PDVSLMEGNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGA----EAIICASTGNTSASAAAYAA 95
Cdd:PRK10717 5 EDVSDTIGNTPLIRLNRASEATGCEILGKAEFLNPGGSVKDRAALNIIWDAEKRGLlkpgGTIVEGTAGNTGIGLALVAA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 96 RLGMKCIIVIPEGKiAHGKLAQAVAYGAEIISIEG----NFDDALRAVRNIAAEEPITLVNSV-------NPYRIEGQ-K 163
Cdd:PRK10717 85 ARGYKTVIVMPETQ-SQEKKDLLRALGAELVLVPAapyaNPNNYVKGAGRLAEELVASEPNGAiwanqfdNPANREAHyE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 164 TAAFEICDQLQNTPDVLAIPVGNAGNITaywkGFCEYEKEKGyKKPRIHGFEAEGAAAI--VKGHVIEAP-ETIATAIRI 240
Cdd:PRK10717 164 TTGPEIWEQTDGKVDGFVCAVGTGGTLA----GVSRYLKETN-PKVKIVLADPTGSALYsyYKTGELKAEgSSITEGIGQ 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2049255829 241 GN-PASWSYA-VEAAEQsngeidmVSDEEILH-AYRLLAKtEGVFAEPGSNASLAGVMKHVQsgKIKKGETVVAVL 313
Cdd:PRK10717 239 GRiTANLEGApIDDAIR-------IPDEEALStAYRLLEE-EGLCLGGSSGINVAAALRLAR--ELGPGHTIVTIL 304
|
|
| cysM |
PRK11761 |
cysteine synthase CysM; |
27-141 |
6.82e-11 |
|
cysteine synthase CysM;
Pssm-ID: 236972 Cd Length: 296 Bit Score: 62.20 E-value: 6.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 27 GNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEG----AEAIICASTGNTSASAAAYAARLGMKCI 102
Cdd:PRK11761 11 GNTPLVKLQRLPPDRGNTILAKLEGNNPAGSVKDRPALSMIVQAEKRGeikpGDTLIEATSGNTGIALAMIAAIKGYRMK 90
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2049255829 103 IVIPEGKIAHGKLAQAvAYGAEII------SIEGNFDDALRAVRN 141
Cdd:PRK11761 91 LIMPENMSQERRAAMR-AYGAELIlvpkeqGMEGARDLALQMQAE 134
|
|
| cysM |
TIGR01138 |
cysteine synthase B; CysM differs from CysK in that it can also use thiosulfate instead of ... |
27-296 |
7.15e-11 |
|
cysteine synthase B; CysM differs from CysK in that it can also use thiosulfate instead of sulfide, to produce cysteine thiosulfonate instead of cysteine. Alternate name: O-acetylserine (thiol)-lyase [Amino acid biosynthesis, Serine family]
Pssm-ID: 130208 [Multi-domain] Cd Length: 290 Bit Score: 62.24 E-value: 7.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 27 GNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEG----AEAIICASTGNTSASAAAYAARLGMKCI 102
Cdd:TIGR01138 7 GNTPLVRLQRMGPENGSEVWLKLEGNNPAGSVKDRPALSMIVEAEKRGeikpGDVLIEATSGNTGIALAMIAALKGYRMK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 103 IVIPEGKIAHGKLAQAvAYGAEII--SIEGNFDDALRAVRNIAAEEPITLV----NSVNPYriEGQKTAAFEICDQLQNT 176
Cdd:TIGR01138 87 LLMPDNMSQERKAAMR-AYGAELIlvTKEEGMEGARDLALELANRGEGKLLdqfnNPDNPY--AHYTSTGPEIWQQTGGR 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 177 PDVLAIPVGNAGNITaywkGFCEYEKEkgYKKP-RIHGFEAEgaaaivKGHVIEAPETIATAIRIGnpaswsyaVEAAEQ 255
Cdd:TIGR01138 164 ITHFVSSMGTTGTIM----GVSRFLKE--QNPPvQIVGLQPE------EGSSIPGIRRWPTEYLPG--------IFDASL 223
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2049255829 256 SNGEIDMvSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMK 296
Cdd:TIGR01138 224 VDRVLDI-HQRDAENTMRELAVREGIFCGVSSGGAVAAALR 263
|
|
| Trp-synth_B |
cd06446 |
Tryptophan synthase-beta: Tryptophan synthase is a bifunctional enzyme that catalyses the ... |
29-320 |
1.17e-10 |
|
Tryptophan synthase-beta: Tryptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to glyceraldehyde 3-phosphate and indole at the active site of the alpha subunit. In the beta reaction, indole undergoes a PLP-dependent reaction with L-serine to form L-tryptophan at the active site of the beta subunit. Members of this CD, Trp-synth_B, are found in all three major phylogenetic divisions.
Pssm-ID: 107207 Cd Length: 365 Bit Score: 62.17 E-value: 1.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQL-GIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIIcAST--GNTSASAAAYAARLGMKCIIVI 105
Cdd:cd06446 35 TPLYRAKRLSEYLgGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKRVI-AETgaGQHGVATATACALFGLECEIYM 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 106 PEGKIAHGKLAQAV--AYGAEIISIEGNF-------DDALR-AVRNIaaEEPITLVNSV---NPYR---IEGQKTAAFEI 169
Cdd:cd06446 114 GAVDVERQPLNVFRmeLLGAEVVPVPSGSgtlkdaiSEAIRdWVTNV--EDTHYLLGSVvgpHPYPnmvRDFQSVIGEEA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 170 CDQLQN----TPDVLAIPVG---NAGNItaywkgFCEYEKEKGykkPRIHGFEAEGAAAIVKGHVieAPETIATA----- 237
Cdd:cd06446 192 KKQILEkegeLPDVVIACVGggsNAAGL------FYPFINDKD---VKLIGVEAGGCGLETGGHA--AYLFGGTAgvlhg 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 238 ---IRIGN-------PASWS----YAVEAAEQSN----GEIDMVS--DEEILHAYRLLAKTEGVFAEPGSNASLAGVMKH 297
Cdd:cd06446 261 lkmYTLQDedgqivpPHSISagldYPGVGPEHAYlkdsGRVEYVAvtDEEALEAFKLLARTEGIIPALESSHAIAYAIKL 340
|
330 340
....*....|....*....|...
gi 2049255829 298 VQsgKIKKGETVVAVLTGNGLKD 320
Cdd:cd06446 341 AK--KLGKEKVIVVNLSGRGDKD 361
|
|
| cysteate_syn |
TIGR03844 |
cysteate synthase; Members of this family are cysteate synthase, an enzyme of alternate ... |
9-319 |
4.07e-10 |
|
cysteate synthase; Members of this family are cysteate synthase, an enzyme of alternate pathway to sulfopyruvate, a precursor of coenzyme M. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Energy metabolism, Methanogenesis]
Pssm-ID: 163556 Cd Length: 398 Bit Score: 60.52 E-value: 4.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 9 YASYLPVNENTPdvslmegnTPLIPLL----NISKQLGI-QLYGKYEGANP-------TGSFKDRGMVMAVAKAKEEGAE 76
Cdd:TIGR03844 47 YYDWLPVTGHLR--------TRGGPVTykseGLARELGLsDLYITFSGYWPergafmrTCSFKELEALPTMQRLKERGGK 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 77 AIICASTGNTSASAAAYAARLGMKCIIVIPEGKIAhgKLAQAV-AYGAEIISIEGNFDDALRAVRNIAAEEPITLVNSV- 154
Cdd:TIGR03844 119 TLVVASAGNTGRAFAEVSAITGQPVILVVPKSSAD--RLWTTEpASSVLLVTVDGDYTDAIALADRIATLPGFVPEGGAr 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 155 NPYRIEGQKTAAFEICDQLQNTPDVLAIPVGNA-GNITAYWKGFCEYEKEK-GYKKPRIH------------GFEAEGAA 220
Cdd:TIGR03844 197 NVARRDGMGTVMLDAAVTIGSLPDHYFQAVGSGtGGIAAWEAAMRLIEDGRfGSKLPRLHlaqnlpfvpmvnAWQEGRRE 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 221 AIVKGHVIEAPETI----ATAIRIGNPaswSYAV-----EAAEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASL 291
Cdd:TIGR03844 277 IIPESDMPDAENSIeevySDVLTNRTP---PYGVtggvfDALIATGGQMYGVSNKEAVSAGKLFEESEGIDILPAAAVAV 353
|
330 340
....*....|....*....|....*...
gi 2049255829 292 AGVMKHVQSGKIKKGETVVAVLTGNGLK 319
Cdd:TIGR03844 354 AALVKAVESGFIGPDDDILLNITGGGYK 381
|
|
| ACCD |
cd06449 |
Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme ... |
29-315 |
3.30e-09 |
|
Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia.
Pssm-ID: 107210 Cd Length: 307 Bit Score: 57.43 E-value: 3.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLG--IQLYGKYEGANPTGSF---KDRGMVMAVAKAKEEGAEAIICAS--TGNTSASAAAYAARLGMKC 101
Cdd:cd06449 1 TPIQYLPRLSEHLGgkVEIYAKRDDCNSGLAFggnKIRKLEYLLPDALAKGADTLVTVGgiQSNHTRQVAAVAAKLGLKC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 102 IIVIpEGKIAH--------GKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEE---------PITLVNSVNPYRIEGQKT 164
Cdd:cd06449 81 VLVQ-ENWVPYsdavydrvGNILLSRIMGADVRLVSAGFDIGIRKSFEEAAEEveakggkpyVIPAGGSEHPLGGLGYVG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 165 AAFEICDQLQNTP---DVLAIPVGNAGNITAYWKGFCEYEKEKgykkpRIHGFEAEGAAAivkghvieapETIATAIRIG 241
Cdd:cd06449 160 FVLEIAQQEEELGfkfDSIVVCSVTGSTHAGLSVGLAALGRQR-----RVIGIDASAKPE----------KTKAQVLRIA 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 242 NPASWSYAVEAAEQSNGEIDM-------VSDEEILHAYRLLAKTEGVFAEPGSNA-SLAGVMKHVQSGKIKKGETVVAVL 313
Cdd:cd06449 225 QAKLAEEGLEVKEEDVVLDDDyaapeygIPNDETIEAIKLCARLEGIITDPVYEGkSMQGMIDLVRNGEFKEGSKVLFIH 304
|
..
gi 2049255829 314 TG 315
Cdd:cd06449 305 LG 306
|
|
| PRK03910 |
PRK03910 |
D-cysteine desulfhydrase; Validated |
20-315 |
8.16e-09 |
|
D-cysteine desulfhydrase; Validated
Pssm-ID: 179673 Cd Length: 331 Bit Score: 56.38 E-value: 8.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 20 PDVSLMEGNTPLIPLLNISKQLGIQLYGKYEGANP--TGSFKDRGMVMAVAKAKEEGAEAII-C-ASTGNTSASAAAYAA 95
Cdd:PRK03910 7 PRLELAGLPTPLEPLPRLSAALGPDIYIKRDDLTGlaLGGNKTRKLEFLLADALAQGADTLItAgAIQSNHARQTAAAAA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 96 RLGMKCIIVIPEGKIAHGKLAQAVA-------YGAEIISIEG--NFDDALRAV-RNIAAEEPitlvnsvNPYRIE----- 160
Cdd:PRK03910 87 KLGLKCVLLLENPVPTEAENYLANGnvllddlFGAEIHVVPAgtDMDAQLEELaEELRAQGR-------RPYVIPvggsn 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 161 -----GQKTAAFEICDQLQNT---PDVLAIPVGNAGNITAYWKGF--CEYE---------KEKGYKKPRIHGFEAEGAAA 221
Cdd:PRK03910 160 algalGYVACALEIAQQLAEGgvdFDAVVVASGSGGTHAGLAAGLaaLGPDipvigvtvsRSAAEQEPKVAKLAQATAEL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 222 IVKGHVIEAPETIATAIRIGnPAswsYAveaaeqsngeidmVSDEEILHAYRLLAKTEGVFAEPG-SNASLAGVMKHVQS 300
Cdd:PRK03910 240 LGLPTEIPRADIRLWDDYVG-PG---YG-------------VPTDEMLEAVKLLARTEGILLDPVyTGKAMAGLIDLIRQ 302
|
330
....*....|....*
gi 2049255829 301 GKIKKGETVVAVLTG 315
Cdd:PRK03910 303 GRFKKGGNVLFIHTG 317
|
|
| PLN02356 |
PLN02356 |
phosphateglycerate kinase |
14-107 |
1.15e-08 |
|
phosphateglycerate kinase
Pssm-ID: 215204 Cd Length: 423 Bit Score: 56.15 E-value: 1.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 14 PVNENTPDVSLME--GNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEA----IICASTGNTS 87
Cdd:PLN02356 37 PLSKKKPRNGLIDaiGNTPLIRINSLSEATGCEILGKCEFLNPGGSVKDRVAVKIIEEALESGQLFpggvVTEGSAGSTA 116
|
90 100
....*....|....*....|
gi 2049255829 88 ASAAAYAARLGMKCIIVIPE 107
Cdd:PLN02356 117 ISLATVAPAYGCKCHVVIPD 136
|
|
| PRK13803 |
PRK13803 |
bifunctional phosphoribosylanthranilate isomerase/tryptophan synthase subunit beta; Provisional |
29-325 |
1.38e-08 |
|
bifunctional phosphoribosylanthranilate isomerase/tryptophan synthase subunit beta; Provisional
Pssm-ID: 237513 [Multi-domain] Cd Length: 610 Bit Score: 56.36 E-value: 1.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIIcAST--GNTSASAAAYAARLGMKCIIVIP 106
Cdd:PRK13803 272 TPLTEAKRLSDIYGARIYLKREDLNHTGSHKINNALGQALLAKRMGKTRII-AETgaGQHGVATATACALFGLKCTIFMG 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 107 EGKIAhgKLAQAVA----YGAEIISIEG---NFDDAL-RAVRNIAAEEPIT--LVNSV---NPY--------RIEGQKTA 165
Cdd:PRK13803 351 EEDIK--RQALNVErmklLGANVIPVLSgskTLKDAVnEAIRDWVASVPDThyLIGSAvgpHPYpemvayfqSVIGEEAK 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 166 AfEICDQLQNTPDVLAIPVGNAGNITAYWKGFCEYEKEKGYkkprihGFEAEG--------AAAIVKGH--VIEAPETIA 235
Cdd:PRK13803 429 E-QLKEQTGKLPDAIIACVGGGSNAIGIFYHFLDDPSVKLI------GVEAGGkgvntgehAATIKKGRkgVLHGSMTYL 501
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 236 TAIRIGNPASwSYAVEAA--------EQSN----GEIDM--VSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKhvQSG 301
Cdd:PRK13803 502 MQDENGQILE-PHSISAGldypgigpMHANlfetGRAIYtsVTDEEALDAFKLLAKLEGIIPALESSHALAYLKE--GRK 578
|
330 340
....*....|....*....|....
gi 2049255829 302 KIKKGETVVAVLTGNGLKDPDIAI 325
Cdd:PRK13803 579 KFKKKDIVIVNLSGRGDKDIPTLK 602
|
|
| PRK08206 |
PRK08206 |
diaminopropionate ammonia-lyase; Provisional |
29-146 |
2.45e-08 |
|
diaminopropionate ammonia-lyase; Provisional
Pssm-ID: 236186 Cd Length: 399 Bit Score: 55.27 E-value: 2.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 29 TPLIPLLNISKQLGI-QLYGKYEGAN-PTGSFKDRGMVMAVAK----------------------AKEEGAEA-IICAST 83
Cdd:PRK08206 45 TPLVALPDLAAELGVgSILVKDESYRfGLNAFKALGGAYAVARllaeklgldiselsfeeltsgeVREKLGDItFATATD 124
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2049255829 84 GNTSASAAAYAARLGMKCIIVIPEGkIAHGKLAQAVAYGAEIISIEGNFDDALRAVRNIAAEE 146
Cdd:PRK08206 125 GNHGRGVAWAAQQLGQKAVIYMPKG-SSEERVDAIRALGAECIITDGNYDDSVRLAAQEAQEN 186
|
|
| PLN00011 |
PLN00011 |
cysteine synthase |
21-317 |
3.00e-08 |
|
cysteine synthase
Pssm-ID: 177651 Cd Length: 323 Bit Score: 54.62 E-value: 3.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 21 DVSLMEGNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEE-----GAEAIICASTGNTSASAAAYAA 95
Cdd:PLN00011 10 DVTELIGNTPMVYLNNIVDGCVARIAAKLEMMEPCSSVKDRIAYSMIKDAEDKglitpGKSTLIEATAGNTGIGLACIGA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 96 RLGMKCIIVIP-----EGKIAHGKLAQAVAYGAEIISIEGNFDDALRAV-RNIAAEEPITLVNSVNP---YRIEGQktaa 166
Cdd:PLN00011 90 ARGYKVILVMPstmslERRIILRALGAEVHLTDQSIGLKGMLEKAEEILsKTPGGYIPQQFENPANPeihYRTTGP---- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 167 fEICDQLQNTPDVLAIPVGNAGNITaywkGFCEYEKEKGyKKPRIHGFEAEGAAAIVKG----HVIEApetIATAIRign 242
Cdd:PLN00011 166 -EIWRDSAGKVDILVAGVGTGGTAT----GVGKFLKEKN-KDIKVCVVEPVESAVLSGGqpgpHLIQG---IGSGII--- 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2049255829 243 PASWSYAVEaaeqsnGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKhVQSGKIKKGETVVAVLTGNG 317
Cdd:PLN00011 234 PFNLDLTIV------DEIIQVTGEEAIETAKLLALKEGLLVGISSGAAAAAALK-VAKRPENAGKLIVVIFPSGG 301
|
|
| PLN02565 |
PLN02565 |
cysteine synthase |
21-317 |
1.69e-06 |
|
cysteine synthase
Pssm-ID: 166206 Cd Length: 322 Bit Score: 49.15 E-value: 1.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 21 DVSLMEGNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEE-----GAEAIICASTGNTSASAAAYAA 95
Cdd:PLN02565 8 DVTELIGKTPLVYLNNVVDGCVARIAAKLEMMEPCSSVKDRIGYSMITDAEEKglikpGESVLIEPTSGNTGIGLAFMAA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 96 RLGMKCIIVIPeGKIAHGKLAQAVAYGAEIISIEG--NFDDALRAVRNIAAEEPITLV-----NSVNPyRIEGQKTAAfE 168
Cdd:PLN02565 88 AKGYKLIITMP-ASMSLERRIILLAFGAELVLTDPakGMKGAVQKAEEILAKTPNSYIlqqfeNPANP-KIHYETTGP-E 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 169 ICDQLQNTPDVLAIPVGNAGNITaywkGFCEYEKEKGyKKPRIHGFEAEGAAAIVKGHviEAPETIAtairiGNPASWSY 248
Cdd:PLN02565 165 IWKGTGGKVDAFVSGIGTGGTIT----GAGKYLKEQN-PDIKLYGVEPVESAVLSGGK--PGPHKIQ-----GIGAGFIP 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2049255829 249 AVEAAEQSNgEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSGKiKKGETVVAVLTGNG 317
Cdd:PLN02565 233 GVLDVDLLD-EVVQVSSDEAIETAKLLALKEGLLVGISSGAAAAAAIKIAKRPE-NAGKLIVVIFPSFG 299
|
|
| PLN03013 |
PLN03013 |
cysteine synthase |
21-296 |
1.90e-05 |
|
cysteine synthase
Pssm-ID: 178587 [Multi-domain] Cd Length: 429 Bit Score: 46.31 E-value: 1.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 21 DVSLMEGNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEE-----GAEAIICASTGNTSASAAAYAA 95
Cdd:PLN03013 116 NVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKgfispGKSVLVEPTSGNTGIGLAFIAA 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 96 RLGMKCIIVIPeGKIAHGKLAQAVAYGAEIISIE--GNFDDALRAVRNIAAEEPITLV-----NSVNPyRIEGQKTAAfE 168
Cdd:PLN03013 196 SRGYRLILTMP-ASMSMERRVLLKAFGAELVLTDpaKGMTGAVQKAEEILKNTPDAYMlqqfdNPANP-KIHYETTGP-E 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 169 ICDQLQNTPDVLAIPVGNAGNITaywkGFCEYEKEKGyKKPRIHGFEAEGAAAIVKGHviEAPETIATAIRIGNPASWSy 248
Cdd:PLN03013 273 IWDDTKGKVDIFVAGIGTGGTIT----GVGRFIKEKN-PKTQVIGVEPTESDILSGGK--PGPHKIQGIGAGFIPKNLD- 344
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2049255829 249 aveaaEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMK 296
Cdd:PLN03013 345 -----QKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIK 387
|
|
| PLN02618 |
PLN02618 |
tryptophan synthase, beta chain |
42-325 |
4.09e-05 |
|
tryptophan synthase, beta chain
Pssm-ID: 215333 Cd Length: 410 Bit Score: 45.13 E-value: 4.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 42 GIQLYGKYEGANPTGSFKDRGMVMAVAKAKEEGAEAIICAS-TGNTSASAAAYAARLGMKCIIVIPEGKIAHGKLA--QA 118
Cdd:PLN02618 86 GPEIYLKREDLNHTGAHKINNAVAQALLAKRLGKKRIIAETgAGQHGVATATVCARFGLECIVYMGAQDMERQALNvfRM 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 119 VAYGAEIISI---EGNFDDAL-RAVRNIAAEEPIT--LVNSV---NPY--------RIEGQKTAAfEICDQLQNTPDVLA 181
Cdd:PLN02618 166 RLLGAEVRPVhsgTATLKDATsEAIRDWVTNVETThyILGSVagpHPYpmmvrdfhSVIGKETRR-QAMEKWGGKPDVLV 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 182 IPVGNAGNITAYWKGFCEYEKekgykkPRIHGFEAEG--------AAAIVKGHV-----------------IEAPETIAT 236
Cdd:PLN02618 245 ACVGGGSNAMGLFHEFIDDED------VRLIGVEAAGfgldsgkhAATLTKGEVgvlhgamsyllqdedgqIIEPHSISA 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 237 AIR---IGNPASWSYAVEAAEqsngeIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSgkIKKGETVVAVL 313
Cdd:PLN02618 319 GLDypgVGPEHSFLKDTGRAE-----YYSVTDEEALEAFQRLSRLEGIIPALETSHALAYLEKLCPT--LPDGTKVVVNC 391
|
330
....*....|..
gi 2049255829 314 TGNGLKDPDIAI 325
Cdd:PLN02618 392 SGRGDKDVNTAI 403
|
|
| PRK12390 |
PRK12390 |
1-aminocyclopropane-1-carboxylate deaminase; Provisional |
20-309 |
1.18e-04 |
|
1-aminocyclopropane-1-carboxylate deaminase; Provisional
Pssm-ID: 183494 Cd Length: 337 Bit Score: 43.48 E-value: 1.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 20 PDVSLMEGNTPLIPLLNISKQLG--IQLYGKYEGANPTGSF---KDRGMVMAVAKAKEEGAEAIIcaSTG----NTSASA 90
Cdd:PRK12390 7 PRYPLTFGPTPIHPLKRLSAHLGgkVELYAKREDCNSGLAFggnKTRKLEYLVPDALAQGADTLV--SIGgvqsNHTRQV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 91 AAYAARLGMKCIIV----IPE--------GKIAHGKLAQA----VAYGAEiISIEGNFDDALRAVRNIAAEE-PITLVNS 153
Cdd:PRK12390 85 AAVAAHLGMKCVLVqenwVNYedavydrvGNILLSRIMGAdvrlVPDGFD-IGIRKSWEDALEDVRAAGGKPyAIPAGAS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 154 VNPYRIEGQKTAAFEICDQ---LQNTPD--VLAIPVGN--AGNITaywkGFCEYEKEKgykkpRIHGFEAEGAAAIVKGH 226
Cdd:PRK12390 164 DHPLGGLGFVGFAEEVRAQeaeLGFKFDyiVVCSVTGStqAGMVV----GFAADGRAR-----RVIGIDASAKPEQTRAQ 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 227 VIEAPETIATAIRIGNPASwSYAVEAAEQSNGEIDMVSDEEILHAYRLLAKTEGVFAEP-GSNASLAGVMKHVQSGKIKK 305
Cdd:PRK12390 235 VLRIARNTAELVELGRDIT-EDDVVLDERYAGPEYGLPNEGTLEAIRLCARLEGMLTDPvYEGKSMHGMIDLVRKGEFPE 313
|
....
gi 2049255829 306 GETV 309
Cdd:PRK12390 314 GSKV 317
|
|
| PRK13028 |
PRK13028 |
tryptophan synthase subunit beta; Provisional |
259-322 |
4.35e-04 |
|
tryptophan synthase subunit beta; Provisional
Pssm-ID: 183851 Cd Length: 402 Bit Score: 41.78 E-value: 4.35e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2049255829 259 EIDMVSDEEILHAYRLLAKTEGVFAEPGSNASLAGVMKHVQSgkIKKGETVVAVLTGNGLKDPD 322
Cdd:PRK13028 330 EYVTATDEEALDAFFLLSRTEGIIPALESSHAVAYAIKLAPE--LSKDETILVNLSGRGDKDID 391
|
|
| PLN02556 |
PLN02556 |
cysteine synthase/L-3-cyanoalanine synthase |
6-126 |
1.07e-03 |
|
cysteine synthase/L-3-cyanoalanine synthase
Pssm-ID: 178171 [Multi-domain] Cd Length: 368 Bit Score: 40.71 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049255829 6 LKQYASYLPVNENTPDVSLMEGNTPLIPLLNISKQLGIQLYGKYEGANPTGSFKDRGMVMAVAKAKEE-----GAEAIIC 80
Cdd:PLN02556 37 LRDLPKDLPGTKIKTDASQLIGKTPLVYLNKVTEGCGAYIAAKQEMFQPTSSIKDRPALAMIEDAEKKnlitpGKTTLIE 116
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2049255829 81 ASTGNTSASAAAYAARLGMKCIIVIPegkiAHGKLAQAV---AYGAEII 126
Cdd:PLN02556 117 PTSGNMGISLAFMAAMKGYKMILTMP----SYTSLERRVtmrAFGAELV 161
|
|
| PRK04346 |
PRK04346 |
tryptophan synthase subunit beta; Validated |
263-325 |
1.31e-03 |
|
tryptophan synthase subunit beta; Validated
Pssm-ID: 235288 Cd Length: 397 Bit Score: 40.43 E-value: 1.31e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2049255829 263 VSDEEILHAYRLLAKTEGVFA--EPgSNAsLAGVMKHvqSGKIKKGETVVAVLTGNGLKDPDIAI 325
Cdd:PRK04346 330 ITDDEALEAFQLLSRLEGIIPalES-SHA-LAYALKL--APTLGKDQIIVVNLSGRGDKDVFTVA 390
|
|
| PRK12391 |
PRK12391 |
TrpB-like pyridoxal phosphate-dependent enzyme; |
29-79 |
7.44e-03 |
|
TrpB-like pyridoxal phosphate-dependent enzyme;
Pssm-ID: 237087 Cd Length: 427 Bit Score: 37.85 E-value: 7.44e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 2049255829 29 TPLIPLLNISKQLG--IQLYGKYEGANPTGSFKdrgMVMAVAKA---KEEGAEAII 79
Cdd:PRK12391 78 TPLIRARRLEKALGtpAKIYYKYEGVSPTGSHK---PNTAVAQAyynKKEGIKRLT 130
|
|
| |
