NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2049720305|gb|QWH92860|]
View 

MarR family transcriptional regulator [Bacillus mycoides]

Protein Classification

MarR family winged helix-turn-helix transcriptional regulator( domain architecture ID 11448790)

MarR family winged helix-turn-helix (wHTH) transcriptional regulator similar to Bacillus thuringiensis DNA-binding transcriptional repressor TubR, a DNA-binding protein that is part of the type III plasmid partition system used to ensure correct segregation of the pBtoxis plasmid

Gene Ontology:  GO:0006355|GO:0003700
PubMed:  10498949|28670937
SCOP:  4000246

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
1-138 9.91e-26

DNA-binding transcriptional regulator, MarR family [Transcription];


:

Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 94.65  E-value: 9.91e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049720305   1 MTS-SCSKEAIILYKLHFLNKEVSSKFEGC---TGMSQSRLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANG 76
Cdd:COG1846     1 MSDePDPAEERLGLLLRRLARALRRALDRAlaeLGLTPAQFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKG 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2049720305  77 MITRRKNPDDNRITLVSLTEEGRNKIQVYQEEKERFATSAFKGLSEEERDNLLTMLDRIQEN 138
Cdd:COG1846    81 LVEREPDPEDRRAVLVRLTEKGRALLEEARPALEALLAELLAGLSEEELEALLRLLRRLAEN 142
 
Name Accession Description Interval E-value
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
1-138 9.91e-26

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 94.65  E-value: 9.91e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049720305   1 MTS-SCSKEAIILYKLHFLNKEVSSKFEGC---TGMSQSRLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANG 76
Cdd:COG1846     1 MSDePDPAEERLGLLLRRLARALRRALDRAlaeLGLTPAQFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKG 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2049720305  77 MITRRKNPDDNRITLVSLTEEGRNKIQVYQEEKERFATSAFKGLSEEERDNLLTMLDRIQEN 138
Cdd:COG1846    81 LVEREPDPEDRRAVLVRLTEKGRALLEEARPALEALLAELLAGLSEEELEALLRLLRRLAEN 142
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
25-125 3.27e-21

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 81.87  E-value: 3.27e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049720305   25 KFEGCTGMSQSRLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRITLVSLTEEGRNKIQV 104
Cdd:smart00347   1 EELKPLGLTPTQFLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRREPSPEDRRSVLVSLTEEGRELIEQ 80

                           90       100
                   ....*....|....*....|.
gi 2049720305  105 YQEEKERFATSAFKGLSEEER 125
Cdd:smart00347  81 LLEARSETLAELLAGLTAEEQ 101
MarR pfam01047
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 32-90 2.44e-10

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 426012 [Multi-domain]  Cd Length: 59  Bit Score: 52.55  E-value: 2.44e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2049720305  32 MSQSRLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRIT 90
Cdd:pfam01047   1 LTLTQFHILRILYEHGPLTVSELAEKLGVSKSTVTRVLDRLEKKGLIERSRSPEDRREV 59
PRK03573 PRK03573
transcriptional regulator SlyA; Provisional
 47-142 1.46e-08

transcriptional regulator SlyA; Provisional


Pssm-ID: 179596  Cd Length: 144  Bit Score: 50.00  E-value: 1.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049720305  47 DEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRITLVSLTEEGRNKIQVYQEEKERFATSAFKGLSEEERD 126
Cdd:PRK03573   45 PEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEVEAVINKTRAEILHGISAEEIE 124

                          90
                  ....*....|....*.
gi 2049720305 127 NLLTMLDRIQENIKEL 142
Cdd:PRK03573  125 QLITLIAKLEKNIIEL 140
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 33-99 9.93e-06

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 41.13  E-value: 9.93e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2049720305  33 SQSRLELILQLYEvDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKnpdDNRITLVSLTEEGR 99
Cdd:cd00090     6 DPTRLRILRLLLE-GPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRR---EGRRVYYSLTDAER 68
HTH_metalloreg NF033788
metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense ...
 36-82 6.04e-03

metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.


Pssm-ID: 411368 [Multi-domain]  Cd Length: 76  Bit Score: 33.59  E-value: 6.04e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2049720305  36 RLELILQLYEvDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRK 82
Cdd:NF033788   13 RLRILELLAE-GELCVCELAEALGLSQSAVSQHLKVLRDAGLVTSRR 58
Staph_reg_Sar TIGR01889
staphylococcal accessory regulator family; This model represents a family of transcriptional ...
 48-103 8.23e-03

staphylococcal accessory regulator family; This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions]


Pssm-ID: 130944  Cd Length: 109  Bit Score: 34.15  E-value: 8.23e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2049720305  48 EISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRITLVSLTEEGRNKIQ 103
Cdd:TIGR01889  43 KLTLKEIIKEILIKQSALVKIIKKLSKKGYLSKERSEDDERKVIISINKEQRSKIE 98
 
Name Accession Description Interval E-value
MarR COG1846
DNA-binding transcriptional regulator, MarR family [Transcription];
1-138 9.91e-26

DNA-binding transcriptional regulator, MarR family [Transcription];


Pssm-ID: 441451 [Multi-domain]  Cd Length: 142  Bit Score: 94.65  E-value: 9.91e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049720305   1 MTS-SCSKEAIILYKLHFLNKEVSSKFEGC---TGMSQSRLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANG 76
Cdd:COG1846     1 MSDePDPAEERLGLLLRRLARALRRALDRAlaeLGLTPAQFRVLAALAEAGGLTQSELAERLGLTKSTVSRLLDRLEEKG 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2049720305  77 MITRRKNPDDNRITLVSLTEEGRNKIQVYQEEKERFATSAFKGLSEEERDNLLTMLDRIQEN 138
Cdd:COG1846    81 LVEREPDPEDRRAVLVRLTEKGRALLEEARPALEALLAELLAGLSEEELEALLRLLRRLAEN 142
HTH_MARR smart00347
helix_turn_helix multiple antibiotic resistance protein;
25-125 3.27e-21

helix_turn_helix multiple antibiotic resistance protein;


Pssm-ID: 197670 [Multi-domain]  Cd Length: 101  Bit Score: 81.87  E-value: 3.27e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049720305   25 KFEGCTGMSQSRLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRITLVSLTEEGRNKIQV 104
Cdd:smart00347   1 EELKPLGLTPTQFLVLRILYEEGPLSVSELAKRLGVSPSTVTRVLDRLEKKGLVRREPSPEDRRSVLVSLTEEGRELIEQ 80

                           90       100
                   ....*....|....*....|.
gi 2049720305  105 YQEEKERFATSAFKGLSEEER 125
Cdd:smart00347  81 LLEARSETLAELLAGLTAEEQ 101
MarR pfam01047
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 32-90 2.44e-10

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 426012 [Multi-domain]  Cd Length: 59  Bit Score: 52.55  E-value: 2.44e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2049720305  32 MSQSRLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRIT 90
Cdd:pfam01047   1 LTLTQFHILRILYEHGPLTVSELAEKLGVSKSTVTRVLDRLEKKGLIERSRSPEDRREV 59
HTH_34 pfam13601
Winged helix DNA-binding domain;
36-112 3.32e-09

Winged helix DNA-binding domain;


Pssm-ID: 463932 [Multi-domain]  Cd Length: 80  Bit Score: 50.33  E-value: 3.32e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2049720305  36 RLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNR-ITLVSLTEEGRNKIQVYQEEKERF 112
Cdd:pfam13601   2 RLAIMSYLASVDEADFVELKEALEATDGNLSVHLRKLEKAGYIECDKSFVGRKpRTLYRITPEGREAFEDYVKALKRL 79
PRK03573 PRK03573
transcriptional regulator SlyA; Provisional
 47-142 1.46e-08

transcriptional regulator SlyA; Provisional


Pssm-ID: 179596  Cd Length: 144  Bit Score: 50.00  E-value: 1.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049720305  47 DEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRITLVSLTEEGRNKIQVYQEEKERFATSAFKGLSEEERD 126
Cdd:PRK03573   45 PEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEVEAVINKTRAEILHGISAEEIE 124

                          90
                  ....*....|....*.
gi 2049720305 127 NLLTMLDRIQENIKEL 142
Cdd:PRK03573  125 QLITLIAKLEKNIIEL 140
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 30-89 1.60e-07

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 45.27  E-value: 1.60e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049720305  30 TGMSQSRLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRI 89
Cdd:pfam12802   1 LGLTPAQFRVLLALARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLVEREPSPADRRA 60
PRK11512 PRK11512
multiple antibiotic resistance transcriptional regulator MarR;
49-135 5.88e-06

multiple antibiotic resistance transcriptional regulator MarR;


Pssm-ID: 183170  Cd Length: 144  Bit Score: 43.35  E-value: 5.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2049720305  49 ISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRITLVSLTEEGRNKI-QVYQEEKERFATSAFKGLSEEERDN 127
Cdd:PRK11512   55 ITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTTSGAAICeQCHQLVGQDLHQELTKNLTADEVAT 134


                  ....*...
gi 2049720305 128 LLTMLDRI 135
Cdd:PRK11512  135 LEHLLKKV 142
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 33-99 9.93e-06

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 41.13  E-value: 9.93e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2049720305  33 SQSRLELILQLYEvDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKnpdDNRITLVSLTEEGR 99
Cdd:cd00090     6 DPTRLRILRLLLE-GPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRR---EGRRVYYSLTDAER 68
Rfk COG1339
Archaeal CTP-dependent riboflavin kinase [Coenzyme transport and metabolism]; Archaeal ...
 48-103 5.36e-05

Archaeal CTP-dependent riboflavin kinase [Coenzyme transport and metabolism]; Archaeal CTP-dependent riboflavin kinase is part of the Pathway/BioSystem: Riboflavin/FAD biosynthesis


Pssm-ID: 440950 [Multi-domain]  Cd Length: 219  Bit Score: 41.37  E-value: 5.36e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2049720305  48 EISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDnriTLVSLTEEGRNKIQ 103
Cdd:COG1339    22 KISSSELAKRLGISQQTASRRLQELEDAGLIERDLVGDG---QWVKITEKGEELLR 74
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
40-97 1.00e-04

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 38.35  E-value: 1.00e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2049720305   40 ILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKnpdDNRITLVSLTEE 97
Cdd:smart00418   2 ILKLLAEGELCVCELAEILGLSQSTVSHHLKKLREAGLVESRR---EGKRVYYSLTDE 56
ArsR COG0640
DNA-binding transcriptional regulator, ArsR family [Transcription];
35-82 2.57e-04

DNA-binding transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 440405 [Multi-domain]  Cd Length: 92  Bit Score: 37.56  E-value: 2.57e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2049720305  35 SRLELILQLYEvDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRK 82
Cdd:COG0640    21 TRLRILRLLAE-GELCVGELAEALGLSQSTVSHHLKVLREAGLVTSRR 67
COG3432 COG3432
Predicted transcriptional regulator [Transcription];
35-107 7.42e-04

Predicted transcriptional regulator [Transcription];


Pssm-ID: 442658 [Multi-domain]  Cd Length: 83  Bit Score: 36.39  E-value: 7.42e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2049720305  35 SRLELILQLYEV---DEISQKALQQEVNIDNAAITRHLKQLEANGMITRRknpDDNRITLVSLTEEGRNKIQVYQE 107
Cdd:COG3432     5 SRLEIIADILEAlknEGAKKTRIMYKANLSYDRLKKYLDLLEEKGLIEKE---DDGGRRIYRITEKGREFLEKYEE 77
HTH_20 pfam12840
Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in ...
 36-82 1.62e-03

Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.


Pssm-ID: 432824 [Multi-domain]  Cd Length: 61  Bit Score: 34.82  E-value: 1.62e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2049720305  36 RLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRK 82
Cdd:pfam12840  12 RLRILRALVGDEPLTASELARRLDISRNTLSYHLRKLEEAGLVEVVR 58
HTH_24 pfam13412
Winged helix-turn-helix DNA-binding;
34-78 2.71e-03

Winged helix-turn-helix DNA-binding;


Pssm-ID: 404317 [Multi-domain]  Cd Length: 45  Bit Score: 33.95  E-value: 2.71e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2049720305  34 QSRLELILQLYEVDEISQKALQQEVNIDNAAITRHLKQLEANGMI 78
Cdd:pfam13412   1 ETDRKILNLLQENPRISQRELAERLGLSPSTVNRRLKRLEEEGVI 45
HxlR COG1733
DNA-binding transcriptional regulator, HxlR family [Transcription];
46-99 5.07e-03

DNA-binding transcriptional regulator, HxlR family [Transcription];


Pssm-ID: 441339  Cd Length: 108  Bit Score: 34.46  E-value: 5.07e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2049720305  46 VDEISQKALqqevnidnaaiTRHLKQLEANGMITRRKNPDDNRITLVSLTEEGR 99
Cdd:COG1733    45 LPGISQKML-----------TQRLRELEEDGLVERTVYPEVPPRVEYSLTEKGR 87
HTH_metalloreg NF033788
metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense ...
 36-82 6.04e-03

metalloregulator ArsR/SmtB family transcription factor; Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.


Pssm-ID: 411368 [Multi-domain]  Cd Length: 76  Bit Score: 33.59  E-value: 6.04e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2049720305  36 RLELILQLYEvDEISQKALQQEVNIDNAAITRHLKQLEANGMITRRK 82
Cdd:NF033788   13 RLRILELLAE-GELCVCELAEALGLSQSAVSQHLKVLRDAGLVTSRR 58
MntR COG1321
Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];
37-99 6.85e-03

Mn-dependent transcriptional regulator MntR, DtxR family [Transcription];


Pssm-ID: 440932 [Multi-domain]  Cd Length: 135  Bit Score: 34.41  E-value: 6.85e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2049720305  37 LELILQLYEVD-EISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNpddnriTLVSLTEEGR 99
Cdd:COG1321    12 LKAIYELSEEGgPVRTSDIAERLGVSPPSVTEMLKKLEEKGLVEYEPY------GGITLTEEGR 69
Staph_reg_Sar TIGR01889
staphylococcal accessory regulator family; This model represents a family of transcriptional ...
 48-103 8.23e-03

staphylococcal accessory regulator family; This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions]


Pssm-ID: 130944  Cd Length: 109  Bit Score: 34.15  E-value: 8.23e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2049720305  48 EISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRITLVSLTEEGRNKIQ 103
Cdd:TIGR01889  43 KLTLKEIIKEILIKQSALVKIIKKLSKKGYLSKERSEDDERKVIISINKEQRSKIE 98
HTH_27 pfam13463
Winged helix DNA-binding domain;
47-98 9.12e-03

Winged helix DNA-binding domain;


Pssm-ID: 433228 [Multi-domain]  Cd Length: 68  Bit Score: 33.03  E-value: 9.12e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2049720305  47 DEISQKALQQEVNIDNAAITRHLKQLEANGMITRRKNPDDNRITLVSLTEEG 98
Cdd:pfam13463  17 DPKTLADICFRLNVEDSHVSYSLKKLTEAGLVEREGSEEDGRETRVRLTAKG 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH