|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
226-461 |
2.61e-57 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 189.35 E-value: 2.61e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 226 ALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINE--NPELLEYMEYISKGVTQIEKYINTLIDISKTE 303
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDlsPEERRELLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 304 NGYI-LNKEAISMSEFIKDVLVQIEALASTKNLDVEFYKQDNLPKnITIDRELLFRAIMNIISNAIDYSPSQSKLYISVS 382
Cdd:COG2205 81 SGKLsLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPL-VYADPELLEQVLANLLDNAIKYSPPGGTITISAR 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2053302028 383 VHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSHyGMGLYIVNNIVQKHNGTLCIENSVKtGGAMVTIEIPI 461
Cdd:COG2205 160 REGDGVRISVSDNGPGIPEEELERIFERFYRGDNSRGEGGT-GLGLAIVKRIVEAHGGTIWVESEPG-GGTTFTVTLPL 236
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
237-461 |
4.75e-57 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 191.66 E-value: 4.75e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 237 LEENRKEQISALAHDIKTPLTIIHGNTDLLIEiNENPELLEYMEYISKGVTQIEKYINTLIDISKTENGYI-LNKEAISM 315
Cdd:COG0642 106 ANEAKSRFLANVSHELRTPLTAIRGYLELLLE-ELDEEQREYLETILRSADRLLRLINDLLDLSRLEAGKLeLEPEPVDL 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 316 SEFIKDVLVQIEALASTKNLDVEFYKQDNLPkNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDC 395
Cdd:COG0642 185 AELLEEVVELFRPLAEEKGIELELDLPDDLP-TVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREGDRVRISVEDT 263
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2053302028 396 GSGFSKADLSKATEQFYTGDLSRNSKSHyGMGLYIVNNIVQKHNGTLCIENSVkTGGAMVTIEIPI 461
Cdd:COG0642 264 GPGIPPEDLERIFEPFFRTDPSRRGGGT-GLGLAIVKRIVELHGGTIEVESEP-GKGTTFTVTLPL 327
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
211-462 |
7.70e-51 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 177.05 E-value: 7.70e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 211 YEINNVLFSMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIE--INENPELLEYMEYISKGVTQ 288
Cdd:COG5002 135 SLRLSALLLGLLLLAAVERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDgaADDPEERREYLEIILEEAER 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 289 IEKYINTLIDISKTENGYI-LNKEAISMSEFIKDVLVQIEALASTKNLDVEFYKQDNLPKnITIDRELLFRAIMNIISNA 367
Cdd:COG5002 215 LSRLVNDLLDLSRLESGELkLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLL-VLGDPDRLEQVLTNLLDNA 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 368 IDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSH-YGMGLYIVNNIVQKHNGTLCIEN 446
Cdd:COG5002 294 IKYTPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGgTGLGLAIVKHIVEAHGGRIWVES 373
|
250
....*....|....*.
gi 2053302028 447 SVKtGGAMVTIEIPIV 462
Cdd:COG5002 374 EPG-KGTTFTITLPLA 388
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-459 |
1.33e-45 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 154.16 E-value: 1.33e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 352 DRELLFRAIMNIISNAIDYSPSqsKLYISVSVHN--KYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLY 429
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPE--GGTVSISIYDeeEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGHYGMGLY 78
|
90 100 110
....*....|....*....|....*....|
gi 2053302028 430 IVNNIVQKHNGTLCIENSVKtGGAMVTIEI 459
Cdd:cd16975 79 IAKNLVEKHGGSLIIENSQK-GGAEVTVKI 107
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
186-462 |
4.50e-36 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 137.79 E-value: 4.50e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 186 MELLKNTTEKIEQQDLDFVVESSKIYEINNVLFSMDKMKLALKDslekqwMLEENRKEQISA-------LAHDIKTPLTI 258
Cdd:COG5000 145 AELLREALERGWQEEIELTRDGRRTLLVRASPLRDDGYVIVFDD------ITELLRAERLAAwgelarrIAHEIKNPLTP 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 259 IHGNTDLLIEI------NENPELLEYMEYISKGVTQIEKYINTLIDISKTENgyiLNKEAISMSEFIKDVLVQIEALAST 332
Cdd:COG5000 219 IQLSAERLRRKladkleEDREDLERALDTIIRQVDRLKRIVDEFLDFARLPE---PQLEPVDLNELLREVLALYEPALKE 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 333 KNLDVEFYKQDNLPKnITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFY 412
Cdd:COG5000 296 KDIRLELDLDPDLPE-VLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFF 374
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 2053302028 413 TgdlsrnSKSH-YGMGLYIVNNIVQKHNGTLCIENSVKtGGAMVTIEIPIV 462
Cdd:COG5000 375 T------TKPKgTGLGLAIVKKIVEEHGGTIELESRPG-GGTTFTIRLPLA 418
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
246-462 |
4.17e-32 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 125.68 E-value: 4.17e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 246 SALAHDIKTPLTIIHGNTDLLIE----INENPELLEYMEYISKGVTQIEKYINTLIDISKTENgyiLNKEAISMSEFIKD 321
Cdd:COG4191 147 AGIAHEINNPLAAILGNAELLRRrledEPDPEELREALERILEGAERAAEIVRSLRAFSRRDE---EEREPVDLNELIDE 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 322 VLVQIEALASTKNLDVEFYKQDNLPKnITIDRELLFRAIMNIISNAID--YSPSQSKLYISVSVHNKYLKFVVTDCGSGF 399
Cdd:COG4191 224 ALELLRPRLKARGIEVELDLPPDLPP-VLGDPGQLEQVLLNLLINAIDamEEGEGGRITISTRREGDYVVISVRDNGPGI 302
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2053302028 400 SKADLSKATEQFYTgdlsrnSKSHY---GMGLYIVNNIVQKHNGTLCIENSVkTGGAMVTIEIPIV 462
Cdd:COG4191 303 PPEVLERIFEPFFT------TKPVGkgtGLGLSISYGIVEKHGGRIEVESEP-GGGTTFTITLPLA 361
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
238-461 |
5.34e-30 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 119.57 E-value: 5.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 238 EENRKEQISA-------LAHDIKTPLTIIHGNTDLLIEINENPELLEYMEYISKGVTQIEKYINTLIDISKTEngyILNK 310
Cdd:COG3852 125 ELRRAEKLAAvgelaagLAHEIRNPLTGIRGAAQLLERELPDDELREYTQLIIEEADRLNNLVDRLLSFSRPR---PPER 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 311 EAISMSEFIKDVLVQIEALAStKNLDVEFYKQDNLPkNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSV------- 383
Cdd:COG3852 202 EPVNLHEVLERVLELLRAEAP-KNIRIVRDYDPSLP-EVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRVerqvtlg 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 384 ---HNKYLKFVVTDCGSGFSKADLSKATEQFYTGdlsrnSKSHYGMGLYIVNNIVQKHNGTLCIEnSVKTGGAMVTIEIP 460
Cdd:COG3852 280 glrPRLYVRIEVIDNGPGIPEEILDRIFEPFFTT-----KEKGTGLGLAIVQKIVEQHGGTIEVE-SEPGKGTTFRIYLP 353
|
.
gi 2053302028 461 I 461
Cdd:COG3852 354 L 354
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
243-461 |
1.15e-28 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 118.35 E-value: 1.15e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 243 EQISALA-HDIKTPLTIIHGNTDLLIEINE---NPELLEYMEYISKGVTQIEKYINTLIDISKTENGyILNKEAISMSEF 318
Cdd:COG4251 283 EQFAYVAsHDLREPLRKISGFSQLLEEDYGdklDEEGREYLERIRDAAERMQALIDDLLAYSRVGRQ-ELEFEPVDLNEL 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 319 IKDVLVQIEALASTKNLDVEFykqDNLPKnITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSV--HNKYLKFVVTDCG 396
Cdd:COG4251 362 LEEVLEDLEPRIEERGAEIEV---GPLPT-VRGDPTLLRQVFQNLISNAIKYSRPGEPPRIEIGAerEGGEWVFSVRDNG 437
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2053302028 397 SGFSKADLSKATEQFYTGdlsrNSKSHY---GMGLYIVNNIVQKHNGTLCIEnSVKTGGAMVTIEIPI 461
Cdd:COG4251 438 IGIDPEYAEKIFEIFQRL----HSRDEYegtGIGLAIVKKIVERHGGRIWVE-SEPGEGATFYFTLPK 500
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
351-461 |
1.11e-26 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 103.50 E-value: 1.11e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 351 IDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYI 430
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRKIGGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|.
gi 2053302028 431 VNNIVQKHNGTLCIENSVKtGGAMVTIEIPI 461
Cdd:smart00387 81 VKKLVELHGGEISVESEPG-GGTTFTITLPL 110
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
220-461 |
4.29e-24 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 104.54 E-value: 4.29e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 220 MDKMKLALkdslekqwmleENRK--EQ-ISALAHDIKTPLTIIHGNTDLLIEinENPE--LLEYMEYISKGVTQIEKYIN 294
Cdd:PRK11100 243 LESMRVKL-----------EGKAyvEQyVQTLTHELKSPLAAIRGAAELLQE--DPPPedRARFTGNILTQSARLQQLID 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 295 TLIDISKTEN-GYILNKEAISMSEFIKDVLVQIEALASTKNLDVEFYKQDNlpkNITIDRELLFRAIMNIISNAIDYSPS 373
Cdd:PRK11100 310 RLLELARLEQrQELEVLEPVALAALLEELVEAREAQAAAKGITLRLRPDDA---RVLGDPFLLRQALGNLLDNAIDFSPE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 374 QSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTgdLSR--NSKSHYGMGLYIVNNIVQKHNGTLCIENsVKTG 451
Cdd:PRK11100 387 GGTITLSAEVDGEQVALSVEDQGPGIPDYALPRIFERFYS--LPRpaNGRKSTGLGLAFVREVARLHGGEVTLRN-RPEG 463
|
250
....*....|
gi 2053302028 452 GAMVTIEIPI 461
Cdd:PRK11100 464 GVLATLTLPR 473
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
352-460 |
2.56e-21 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 88.58 E-value: 2.56e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 352 DRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNkYLKFVVTDCGSGFSKADLSKATEQFYTGDLSrnSKSHYGMGLYIV 431
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKHAAKAGEITVTLSEGG-ELTLTVEDNGIGIPPEDLPRIFEPFSTADKR--GGGGTGLGLSIV 78
|
90 100
....*....|....*....|....*....
gi 2053302028 432 NNIVQKHNGTLCIENSVKtGGAMVTIEIP 460
Cdd:pfam02518 79 RKLVELLGGTITVESEPG-GGTTVTLTLP 106
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
219-462 |
8.29e-21 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 94.61 E-value: 8.29e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 219 SMDKMKLALKDSLEKQWMLeenrkeqISALAHDIKTPLTIIHGNTDLLIEIN-ENPELleymEYISKGVTQIEKYINTLI 297
Cdd:PRK09470 228 SFNQMVTALERMMTSQQRL-------LSDISHELRTPLTRLQLATALLRRRQgESKEL----ERIETEAQRLDSMINDLL 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 298 DISKTENGYILNKEAISMSEFIKDVL--VQIEALASTKNLDVEFykqdnLPKNITI--DRELLFRAIMNIISNAIDYspS 373
Cdd:PRK09470 297 VLSRNQQKNHLERETFKANSLWSEVLedAKFEAEQMGKSLTVSA-----PPGPWPIngNPNALASALENIVRNALRY--S 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 374 QSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKS-HYGMGLYIVNNIVQKHNGTLCIENSvKTGG 452
Cdd:PRK09470 370 HTKIEVAFSVDKDGLTITVDDDGPGVPEEEREQIFRPFYRVDEARDRESgGTGLGLAIVENAIQQHRGWVKAEDS-PLGG 448
|
250
....*....|
gi 2053302028 453 AMVTIEIPIV 462
Cdd:PRK09470 449 LRLTIWLPLY 458
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
249-462 |
2.53e-19 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 90.42 E-value: 2.53e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 249 AHDIKTPLTIIHGNTDLLiEINENPELLEYMEYISKGVTQIEKYINTLIDISKTENGyilNKEAISMSEFIKDVLVQIEA 328
Cdd:COG5809 278 AHEIRNPLTSLKGFIQLL-KDTIDEEQKTYLDIMLSELDRIESIISEFLVLAKPQAI---KYEPKDLNTLIEEVIPLLQP 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 329 LASTKNLDVEFYKQDNLPkNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVH-NKYLKFVVTDCGSGFSKADLSKA 407
Cdd:COG5809 354 QALLKNVQIELELEDDIP-DILGDENQLKQVFINLLKNAIEAMPEGGNITIETKAEdDDKVVISVTDEGCGIPEERLKKL 432
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2053302028 408 TEQFYTgdlsrNSKSHYGMGLYIVNNIVQKHNGTLCIEnSVKTGGAMVTIEIPIV 462
Cdd:COG5809 433 GEPFYT-----TKEKGTGLGLMVSYKIIEEHGGKITVE-SEVGKGTTFSITLPIK 481
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
225-461 |
1.83e-18 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 88.10 E-value: 1.83e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 225 LALKDSLEKQWMLEE-NRKEQISAL-------AHDIKTPLTIIHGNTDLLIEINENPELLEYMEYISKGVTQIEKYINTL 296
Cdd:PRK11360 366 VIFSDLTERKRLQRRvARQERLAALgelvagvAHEIRNPLTAIRGYVQIWRQQTSDPPSQEYLSVVLREVDRLNKVIDQL 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 297 IDISKTENGYIlnkEAISMSEFIKDVLVQIEALASTKNLDVEFYKQDNLPKnITIDRELLFRAIMNIISNAIDYSPSQSK 376
Cdd:PRK11360 446 LEFSRPRESQW---QPVSLNALVEEVLQLFQTAGVQARVDFETELDNELPP-IWADPELLKQVLLNILINAVQAISARGK 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 377 LYISVSVHNKYLKFV-VTDCGSGFSKADLSKATEQFYTgdlSRNSKShyGMGLYIVNNIVQKHNGTLCIENSVKtGGAMV 455
Cdd:PRK11360 522 IRIRTWQYSDGQVAVsIEDNGCGIDPELLKKIFDPFFT---TKAKGT--GLGLALSQRIINAHGGDIEVESEPG-VGTTF 595
|
....*.
gi 2053302028 456 TIEIPI 461
Cdd:PRK11360 596 TLYLPI 601
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
233-461 |
1.97e-18 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 87.53 E-value: 1.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 233 KQWMLEE-NRKEQISAL-------AHDIKTPLTIIHGNTDLLIEI----NENPELLEYMeyiSKGVTQIEKYINTLIDIS 300
Cdd:PRK10364 221 RQLLQDEmKRKEKLVALghlaagvAHEIRNPLSSIKGLAKYFAERapagGEAHQLAQVM---AKEADRLNRVVSELLELV 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 301 KTENgyiLNKEAISMSEFIKDVLVQIEALASTKNLDVEFYKQDNLPKnITIDRELLFRAIMNIISNAIDYSPSQSKLYIS 380
Cdd:PRK10364 298 KPTH---LALQAVDLNDLINHSLQLVSQDANSREIQLRFTANDTLPE-IQADPDRLTQVLLNLYLNAIQAIGQHGVISVT 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 381 VSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTgdlSRNSKShyGMGLYIVNNIVQKHNGTLCIEnSVKTGGAMVTIEIP 460
Cdd:PRK10364 374 ASESGAGVKISVTDSGKGIAADQLEAIFTPYFT---TKAEGT--GLGLAVVHNIVEQHGGTIQVA-SQEGKGATFTLWLP 447
|
.
gi 2053302028 461 I 461
Cdd:PRK10364 448 V 448
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
224-460 |
1.50e-17 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 85.47 E-value: 1.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 224 KLALKDSlEKQWMLEENRkEQI-----SALAHDIKTPLTIIHGNTDLLIE--INENPELLEYMEYISKGVTQIEKYINTL 296
Cdd:PRK10490 644 RLTLTAS-EEQARLASER-EQLrnallAALSHDLRTPLTVLFGQAEILTLdlASEGSPHARQASEIRQQVLNTTRLVNNL 721
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 297 IDISKTENGYI-LNKEAISMSEFIKDVLVQIEALASTKNLDVefykqdNLPKNITI---DRELLFRAIMNIISNAIDYSP 372
Cdd:PRK10490 722 LDMARIQSGGFnLRKEWLTLEEVVGSALQMLEPGLSGHPINL------SLPEPLTLihvDGPLFERVLINLLENAVKYAG 795
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 373 SQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFytgdlSRNSKSH----YGMGLYIVNNIVQKHNGTLCIENSV 448
Cdd:PRK10490 796 AQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKF-----ARGNKESaipgVGLGLAICRAIVEVHGGTIWAENRP 870
|
250
....*....|..
gi 2053302028 449 KtGGAMVTIEIP 460
Cdd:PRK10490 871 E-GGACFRVTLP 881
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
244-462 |
2.79e-17 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 84.01 E-value: 2.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 244 QISA-LAHDIKTPLTIIHGNTDLL-IEINENPElleYMEYISKGVTQIEKYINTLIDISKTENgyiLNKEAISMSEFIKD 321
Cdd:COG5805 289 QLAAgIAHEIRNPLTSIKGFLQLLqPGIEDKEE---YFDIMLSELDRIESIISEFLALAKPQA---VNKEKENINELIQD 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 322 VLVQIEALASTKNLDVEFYKQDNLPkNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSK 401
Cdd:COG5805 363 VVTLLETEAILHNIQIRLELLDEDP-FIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPE 441
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2053302028 402 ADLSKATEQFYTgdlsrNSKSHYGMGLYIVNNIVQKHNGTLCIENSVKTGGAmVTIEIPIV 462
Cdd:COG5805 442 ERLKKLGEPFFT-----TKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTT-FTITLPLS 496
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
243-462 |
2.81e-17 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 83.36 E-value: 2.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 243 EQISALAHDIKTPLTIIHGntdlLIEINENPELLEYMEYISKGVTQIEKYIntlidISKTENGYIlnkEAIsmsefikdv 322
Cdd:COG3290 191 EALRAQRHDFRNHLHTISG----LLQLGEYDEALEYIDEISEELQELIDSL-----LSRIGNPVL---AAL--------- 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 323 LVQIEALASTKNLDVEFYKQDNLPkNITIDRELLFRAIMNIISNAIDYS----PSQSKLYISVSVHNKYLKFVVTDCGSG 398
Cdd:COG3290 250 LLGKAARARERGIDLTIDIDSDLP-DLPLSDTDLVTILGNLLDNAIEAVeklpEEERRVELSIRDDGDELVIEVEDSGPG 328
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2053302028 399 FSKADLSKATEQfytGDLSRNSKSHyGMGLYIVNNIVQKHNGTLCIENSvKTGGAMVTIEIPIV 462
Cdd:COG3290 329 IPEELLEKIFER---GFSTKLGEGR-GLGLALVKQIVEKYGGTIEVESE-EGEGTVFTVRLPKE 387
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
184-445 |
3.53e-17 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 83.59 E-value: 3.53e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 184 IEMELLKNTTEKIEQ---QDLDFVVESSKI-YEINNVLFSMDKMKLALKDSLEKQwmleenrkEQISA-LAHDIKTPLTI 258
Cdd:TIGR01386 187 LGLEPLRRLSAVAARispESLDQRLDPSRApAELRELAQSFNAMLGRLEDAFQRL--------SQFSAdLAHELRTPLTN 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 259 IHGNTDLLIEINENPEllEYMEYISKGVTQIE---KYINTLIDISKTENGYI-LNKEAISMSEFIKDVLVQIEALASTKN 334
Cdd:TIGR01386 259 LLGQTQVALSQPRTGE--EYREVLESNLEELErlsRMVSDMLFLARADNGQLaLERVRLDLAAELAKVAEYFEPLAEERG 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 335 LDVEFYKQDNLPknitIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTG 414
Cdd:TIGR01386 337 VRIRVEGEGLVR----GDPQMFRRAISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRV 412
|
250 260 270
....*....|....*....|....*....|..
gi 2053302028 415 DLSR-NSKSHYGMGLYIVNNIVQKHNGTLCIE 445
Cdd:TIGR01386 413 DPARsNSGEGTGLGLAIVRSIMEAHGGRASAE 444
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-460 |
5.20e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 76.21 E-value: 5.20e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 356 LFRAIMNIISNAIDYSPsqSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSH-YGMGLYIVNNI 434
Cdd:cd16949 1 LARALENVLRNALRYSP--SKILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGgTGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 2053302028 435 VQKHNGTLCIENSvKTGGAMVTIEIP 460
Cdd:cd16949 79 IEQHGGKIKASNR-KPGGLRVRIWLP 103
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
236-462 |
4.06e-16 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 79.95 E-value: 4.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 236 MLEENRKEQISALAHDIKTPLTIIHGNTDLLIEinENpelleymEYISKG-VTQIEK---YINTLIDISKTENGyiLNKE 311
Cdd:PRK09467 224 QLEDDRTLLMAGVSHDLRTPLTRIRLATEMMSE--ED-------GYLAESiNKDIEEcnaIIEQFIDYLRTGQE--MPME 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 312 AISMSEFIKDVlVQIEalaSTKNLDVEFYKQDNlPKNITIDRELLFRAIMNIISNAIDYSPSQSKlyISVSVHNKYLKFV 391
Cdd:PRK09467 293 MADLNALLGEV-IAAE---SGYEREIETALQPG-PIEVPMNPIAIKRALANLVVNAARYGNGWIK--VSSGTEGKRAWFQ 365
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2053302028 392 VTDCGSGFSKADLSKATEQFYTGDLSRNSkSHYGMGLYIVNNIVQKHNGTLCIENSVKtGGAMVTIEIPIV 462
Cdd:PRK09467 366 VEDDGPGIPPEQLKHLFQPFTRGDSARGS-SGTGLGLAIVKRIVDQHNGKVELGNSEE-GGLSARAWLPLT 434
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
189-449 |
1.96e-15 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 78.28 E-value: 1.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 189 LKNTTEKIEQQDLDFVVESSKI-YEINNVLFSMDKMKLALKDSLEKQwmleenrkEQISA-LAHDIKTPLTIIHGNTDLL 266
Cdd:PRK09835 216 VSRQIQNITSKDLDVRLDPQTVpIELEQLVLSFNHMIERIEDVFTRQ--------SNFSAdIAHEIRTPITNLITQTEIA 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 267 IEINENPELLEYMEYIS-KGVTQIEKYINTLIDISKTENG-YILNKEAISMSEFIKDVLVQIEALASTKNLDVEFykqDN 344
Cdd:PRK09835 288 LSQSRSQKELEDVLYSNlEELTRMAKMVSDMLFLAQADNNqLIPEKKMLDLADEVGKVFDFFEAWAEERGVELRF---VG 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 345 LPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSH- 423
Cdd:PRK09835 365 DPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEg 444
|
250 260
....*....|....*....|....*.
gi 2053302028 424 YGMGLYIVNNIVQKHNGTLCIENSVK 449
Cdd:PRK09835 445 SGIGLAIVKSIVVAHKGTVAVTSDAR 470
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
227-462 |
5.49e-15 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 76.98 E-value: 5.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 227 LKDSLEKQwmlEENRKEQISALAHDIKTPLTIIHGntdllieinenpELleymEYISKGVTQ---------------IEK 291
Cdd:PRK10549 229 LASTLEKN---EQMRRDFMADISHELRTPLAVLRG------------EL----EAIQDGVRKftpesvaslqaevgtLTK 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 292 YINTLIDISKTENGYI-LNKEAISMSEfikdvLVQIeALAS------TKNLDVEFykqdNLPKNITI--DRELLFRAIMN 362
Cdd:PRK10549 290 LVDDLHQLSLSDEGALaYRKTPVDLVP-----LLEV-AGGAfrerfaSRGLTLQL----SLPDSATVfgDPDRLMQLFNN 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 363 IISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKS-HYGMGLYIVNNIVQKHNGT 441
Cdd:PRK10549 360 LLENSLRYTDSGGSLHISAEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSRNRASgGSGLGLAICLNIVEAHNGR 439
|
250 260
....*....|....*....|.
gi 2053302028 442 LCIENSvKTGGAMVTIEIPIV 462
Cdd:PRK10549 440 IIAAHS-PFGGVSITVELPLE 459
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-445 |
7.92e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 70.11 E-value: 7.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 356 LFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKShYGMGLYIVNNIV 435
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTEG-AGLGLSIAKAII 79
|
90
....*....|
gi 2053302028 436 QKHNGTLCIE 445
Cdd:cd16923 80 ELHGGSASAE 89
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-460 |
1.22e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 69.80 E-value: 1.22e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 352 DRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKS-HYGMGLYI 430
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASgGSGLGLAI 80
|
90 100 110
....*....|....*....|....*....|
gi 2053302028 431 VNNIVQKHNGTLCIENSvKTGGAMVTIEIP 460
Cdd:cd16946 81 CHNIALAHGGTISAEHS-PLGGLRLVLTLP 109
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
193-451 |
4.58e-13 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 70.81 E-value: 4.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 193 TEKIEQQD----LDFVVESSKIYEINNVLFSMDKMKLALKDSLEKQwMLEENRKEQISALAHDIKTPLTIIHGntdlLIE 268
Cdd:PRK11006 153 TQYLKTRDfsrpLTLVLNNGRHLEIRVMPYTEGQLLMVARDVTQMH-QLEGARRNFFANVSHELRTPLTVLQG----YLE 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 269 INENPELLEYMEYISKGVTQ-----IEKYINTLIDISKTENGyilnkEAISMSEFIkDV-----LVQIEALA-STKNLDV 337
Cdd:PRK11006 228 MMQDQPLEGALREKALHTMReqtqrMEGLVKQLLTLSKIEAA-----PTIDLNEKV-DVpmmlrVLEREAQTlSQGKHTI 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 338 EFYKQDNLpkNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLS 417
Cdd:PRK11006 302 TFEVDNSL--KVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAEFSVEDNGPGIAPEHIPRLTERFYRVDKA 379
|
250 260 270
....*....|....*....|....*....|....*
gi 2053302028 418 RNSKS-HYGMGLYIVNNIVQKHNGTLCIENSVKTG 451
Cdd:PRK11006 380 RSRQTgGSGLGLAIVKHALSHHDSRLEIESEVGKG 414
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
241-461 |
1.39e-12 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 69.25 E-value: 1.39e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 241 RKEQISALAHDIKTPLTIIHgntdLLIEINENPELLEYMEyISKGVTQIEKYINTLIDISKTENGYI-LNKEAISMSEFI 319
Cdd:PRK10604 212 KKQLIDGIAHELRTPLVRLR----YRLEMSDNLSAAESQA-LNRDIGQLEALIEELLTYARLDRPQNeLHLSEPDLPAWL 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 320 KDVLVQIEALASTKNLDVEFYKQDNLpknITIDRELLFRAIMNIISNAIDYSpsQSKLYISVSVHNKYLKFVVTDCGSGF 399
Cdd:PRK10604 287 STHLADIQAVTPEKTVRLDTPHQGDY---GALDMRLMERVLDNLLNNALRYA--HSRVRVSLLLDGNQACLIVEDDGPGI 361
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2053302028 400 SKADLSKATEQFYTGDLSRNSKSH-YGMGLYIVNNIVQKHNGTLCIENSVkTGGAMVTIEIPI 461
Cdd:PRK10604 362 PPEERERVFEPFVRLDPSRDRATGgCGLGLAIVHSIALAMGGSVNCDESE-LGGARFSFSWPV 423
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-451 |
5.40e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 62.30 E-value: 5.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 352 DRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIV 431
Cdd:cd16948 2 DAKWLSFIIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRNFQESTGMGLYLV 81
|
90 100
....*....|....*....|
gi 2053302028 432 NNIVQKHNGTLCIENSVKTG 451
Cdd:cd16948 82 KKLCDKLGHKIDVESEVGEG 101
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
241-305 |
6.12e-12 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 60.69 E-value: 6.12e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2053302028 241 RKEQISALAHDIKTPLTIIHGNTDLLIEINENPELLEYMEYISKGVTQIEKYINTLIDISKTENG 305
Cdd:pfam00512 2 KSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-457 |
7.72e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 61.71 E-value: 7.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 352 DRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIV 431
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGQKSTGLGLAFV 80
|
90 100
....*....|....*....|....*.
gi 2053302028 432 NNIVQKHNGTLCIENSVKTGGAMVTI 457
Cdd:cd16945 81 QEVAQLHGGRITLRNRPDGVLAFLTL 106
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
241-305 |
1.46e-11 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 59.50 E-value: 1.46e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2053302028 241 RKEQISALAHDIKTPLTIIHGNTDLLIEINENPELLEYMEYISKGVTQIEKYINTLIDISKTENG 305
Cdd:smart00388 2 KREFLANLSHELRTPLTAIRGYLELLLDTELSEEQREYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
353-461 |
2.07e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 60.51 E-value: 2.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 353 RELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTgdlSRNSKSHYGMGLYIVN 432
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFT---TKPVGEGTGLGLSLSY 77
|
90 100
....*....|....*....|....*....
gi 2053302028 433 NIVQKHNGTLCIEnSVKTGGAMVTIEIPI 461
Cdd:cd16943 78 RIIQKHGGTIRVA-SVPGGGTRFTIILPI 105
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-451 |
2.23e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 60.68 E-value: 2.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 356 LFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNS-KSHYGMGLYIVNNI 434
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRnTGGTGLGLAIVKHV 80
|
90
....*....|....*..
gi 2053302028 435 VQKHNGTLCIENSVKTG 451
Cdd:cd16952 81 MSRHDARLLIASELGKG 97
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
346-451 |
2.34e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 60.50 E-value: 2.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 346 PKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLkFVVTDCGSGFSKADLSKATEQFYtgdlsRNSKSHY- 424
Cdd:cd16940 4 DIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDGAV-IRVEDNGPGIDEEELEALFERFY-----RSDGQNYg 77
|
90 100
....*....|....*....|....*....
gi 2053302028 425 --GMGLYIVNNIVQKHNGTLCIENSVKTG 451
Cdd:cd16940 78 gsGLGLSIVKRIVELHGGQIFLGNAQGGG 106
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
238-301 |
3.46e-11 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 58.38 E-value: 3.46e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2053302028 238 EENRKEQISALAHDIKTPLTIIHGNTDLLIE-INENPELLEYMEYISKGVTQIEKYINTLIDISK 301
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEeLLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
352-460 |
1.75e-10 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 57.89 E-value: 1.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 352 DRELLFRAIMNIISNAIDYSPSQSKLYISVSVHN-KYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSH-YGMGLY 429
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCILEKFRlNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGgTGLGLS 80
|
90 100 110
....*....|....*....|....*....|.
gi 2053302028 430 IVNNIVQKHNGTLCIENsVKTGGAMVTIEIP 460
Cdd:cd16925 81 IVKEFVELHGGTVTVSD-APGGGALFQVELP 110
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
236-461 |
2.65e-10 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 62.23 E-value: 2.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 236 MLEENR----KEQISALAHDIKTPLTIIHGNTDLL---IEINENPELLEYMEYISKGVTQIEKYINTLIDISKTENgyil 308
Cdd:TIGR02938 267 MAEEERleaiRETLSAAIHRLQGPMNLISAAISVLqrrGDDAGNPASAAMLQQALSAGREHMEALRQVIPQSPQEI---- 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 309 nKEAISMSEFIKDVLVQIEALASTKNLDVEFYKQDNLPKniTIDRELLFRA-IMNIISNAIDY----SPSQSKLYISVSV 383
Cdd:TIGR02938 343 -VVPVNLNQILRDVITLSTPRLLAAGIVVDWQPAATLPA--ILGRELQLRSlFKALVDNAIEAmnikGWKRRELSITTAL 419
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2053302028 384 HNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSrnSKSHYGMGLYIVNNIVQKHNGTLCIENSVKtGGAMVTIEIPI 461
Cdd:TIGR02938 420 NGDLIVVSILDSGPGIPQDLRYKVFEPFFTTKGG--SRKHIGMGLSVAQEIVADHGGIIDLDDDYS-EGCRIIVEFRV 494
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
355-460 |
2.85e-10 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 61.52 E-value: 2.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 355 LLFRaimNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDlSRNSKShyGMGLYIVNNI 434
Cdd:PRK10755 250 LLLR---NLVENAHRYSPEGSTITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVRMD-SRYGGI--GLGLSIVSRI 323
|
90 100
....*....|....*....|....*.
gi 2053302028 435 VQKHNGTLCIENSVKTGGAMVTIEIP 460
Cdd:PRK10755 324 TQLHHGQFFLQNRQERSGTRAWVWLP 349
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
239-461 |
2.87e-10 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 62.74 E-value: 2.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 239 ENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPE---LLEYMEYISKGVTQIekyINTLIDISKTENGYI-LNKEAIS 314
Cdd:PRK15347 396 KRKSEHLTTISHEIRTPLNGVLGALELLQNTPLTAEqmdLADTARQCTLSLLAI---INNLLDFSRIESGQMtLSLEETA 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 315 MSEFIKDVLVQIEALASTKNLDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSkLYISVSVHNKYLKFVVTD 394
Cdd:PRK15347 473 LLPLLDQAMLTIQGPAQSKSLTLRTFVGAHVPLYLHLDSLRLRQILVNLLGNAVKFTETGG-IRLRVKRHEQQLCFTVED 551
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2053302028 395 CGSGFSKADLSKATEQFYTGDlsrNSKSHYGMGLYIVNNIVQKHNGTLCIeNSVKTGGAMVTIEIPI 461
Cdd:PRK15347 552 TGCGIDIQQQQQIFTPFYQAD---THSQGTGLGLTIASSLAKMMGGELTL-FSTPGVGSCFSLVLPL 614
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
236-438 |
2.17e-09 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 59.28 E-value: 2.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 236 MLEENRKeqISALAHDIKTPLTIIHGNTDLLIEINENPELLEY-MEYISKGVTQIEKYINTLIDISKTENGYILNK-EAI 313
Cdd:PRK10337 234 MVRERRF--TSDAAHELRSPLAALKVQTEVAQLSDDDPQARKKaLLQLHAGIDRATRLVDQLLTLSRLDSLDNLQDvAEI 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 314 SMSEFIKDVLVQIEALASTKNLDVEfYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNkylkFVVT 393
Cdd:PRK10337 312 PLEDLLQSAVMDIYHTAQQAGIDVR-LTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARN----FTVR 386
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2053302028 394 DCGSGFSKADLSKATEQFYtgdlsR---NSKSHYGMGLYIVNNIVQKH 438
Cdd:PRK10337 387 DNGPGVTPEALARIGERFY-----RppgQEATGSGLGLSIVRRIAKLH 429
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
237-460 |
3.01e-09 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 59.18 E-value: 3.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 237 LEENRKEQ---ISALAHDIKTPLTIIHGNTDLLIEINENPELLEYMEYI-SKGVTqIEKYINTLIDISKTENGYI-LNKE 311
Cdd:PRK11091 276 LEKASRDKttfISTISHELRTPLNGIVGLSRILLDTELTAEQRKYLKTIhVSAIT-LGNIFNDIIDMDKMERRKLqLDNQ 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 312 AISMSEFIKDVLVQIEALASTKNLDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPsQSKLYISVSVH-NKYLKF 390
Cdd:PRK11091 355 PIDFTDFLADLENLSGLQAEQKGLRFDLEPLLPLPHKVITDGTRLRQILWNLISNAVKFTQ-QGGVTVRVRYEeGDMLTF 433
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2053302028 391 VVTDCGSGFSKADLSKATEQFYTGDLSRNSKSHY--GMGLYIVNNIVQKHNGTLCIeNSVKTGGAMVTIEIP 460
Cdd:PRK11091 434 EVEDSGIGIPEDELDKIFAMYYQVKDSHGGKPATgtGIGLAVSKRLAQAMGGDITV-TSEEGKGSCFTLTIH 504
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
358-460 |
3.52e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 53.99 E-value: 3.52e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 358 RAIMNIISNAIDYSpsqsKLYISVS--VHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKSHyGMGLYIVNNIV 435
Cdd:cd16950 3 RVLSNLVDNALRYG----GGWVEVSsdGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARGTSGT-GLGLAIVQRIS 77
|
90 100
....*....|....*....|....*
gi 2053302028 436 QKHNGTLCIENSvKTGGAMVTIEIP 460
Cdd:cd16950 78 DAHGGSLTLANR-AGGGLCARIELP 101
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
354-460 |
4.82e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 53.55 E-value: 4.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 354 ELLFRAIMNIISNAIDYSPSQSKLYISVSVHNK-YLKFVVTDCGSGFSKADLSKATEQFYTgdlsrNSKSHYGMGLYIVN 432
Cdd:cd16920 3 QVLINLVRNGIEAMSEGGCERRELTIRTSPADDrAVTISVKDTGPGIAEEVAGQLFDPFYT-----TKSEGLGMGLSICR 77
|
90 100
....*....|....*....|....*...
gi 2053302028 433 NIVQKHNGTLCIEnSVKTGGAMVTIEIP 460
Cdd:cd16920 78 SIIEAHGGRLSVE-SPAGGGATFQFTLP 104
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
12-461 |
5.44e-09 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 58.11 E-value: 5.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 12 VEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVLLSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDG 91
Cdd:COG2972 12 LLLLILLLLVLLILLLSLLLIILLLLLLLILLLLLLILLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLILLLLLLLLL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 92 SLISGTFNKKESKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPeTLGMIIFSIIFFIEI 171
Cdd:COG2972 92 LLILLLSLLLLLALILLLALLLLLSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFRGLFSL-RRLILLIILLLLLLA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 172 VILSKVFGKKFNIEMELLKNTTEKIEQQDLdFVVESSKIYEINNVLFSMDKMKLALKDSLEKQWMLEENRKE-QISALA- 249
Cdd:COG2972 171 LLLSYLLSRSITRPIKRLKKAMKKVEKGDL-VRLEVSGNDEIGILARSFNEMVERIKELIEEVYELELEKKEaELKALQa 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 250 ----HDIKTPLTIIHGntdlLIEINENPElleymeyiskgvtqIEKYINTLIDIS----KTENGYILNKEAIsmsEFIKD 321
Cdd:COG2972 250 qinpHFLFNTLNSIRW----LAELEDPEE--------------AEEMLEALSKLLryslSKGDELVTLEEEL---ELIKS 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 322 vLVQIEALASTKNLDVEFYKQDNLpknitIDRELLFRAIMNIISNAI----DYSPSQSKLYISVSVHNKYLKFVVTDCGS 397
Cdd:COG2972 309 -YLEIQKLRFGDRLEVEIEIDEEL-----LDLLIPKLILQPLVENAIehgiEPKEGGGTIRISIRKEGDRLVITVEDNGV 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2053302028 398 GFSKADLSKATEQFytgdlsRNSKSHYGMGLYIVNNIVQKHNG---TLCIEnSVKTGGAMVTIEIPI 461
Cdd:COG2972 383 GMPEEKLEKLLEEL------SSKGEGRGIGLRNVRERLKLYYGeeyGLEIE-SEPGEGTTVTIRIPL 442
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-460 |
8.70e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 52.82 E-value: 8.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 356 LFRAIMNIISNAIDYSPSQSKlyISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKS-HYGMGLYIVNNI 434
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVR--IALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATgGFGLGLAIVHRV 78
|
90 100
....*....|....*....|....*.
gi 2053302028 435 VQKHNGTLCIENSvKTGGAMVTIEIP 460
Cdd:cd16939 79 ALWHGGHVECDDS-ELGGACFRLTWP 103
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
241-461 |
1.89e-08 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 57.05 E-value: 1.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 241 RKEQISALAHDIKTPLTIIHGNTDLLIEINENPEllEYMEYISKGVTQIEK---YINTLIDISKTENG-YILNKEAISMS 316
Cdd:PRK09959 712 KSQFLATMSHEIRTPISSIMGFLELLSGSGLSKE--QRVEAISLAYATGQSllgLIGEILDVDKIESGnYQLQPQWVDIP 789
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 317 EFIKDVLVQIEALASTKNLDVEFykQDNLPKN--ITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVH----NKYLKF 390
Cdd:PRK09959 790 TLVQNTCHSFGAIAASKSIALSC--SSTFPDHylVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLGHiddnHAVIKM 867
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2053302028 391 VVTDCGSGFSKADLSKATEQFYTGDLSRNsKSHYGMGLYIVNNIVQKHNGTLCIENSVKTgGAMVTIEIPI 461
Cdd:PRK09959 868 TIMDSGSGLSQEEQQQLFKRYSQTSAGRQ-QTGSGLGLMICKELIKNMQGDLSLESHPGI-GTTFTITIPV 936
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
198-440 |
2.19e-08 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 55.73 E-value: 2.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 198 QQDLDFVV---ESSKIYEINNVLFSMDKMKLAlkDSL-----EKQWMLEE-NRKEQISA-LAHDIKTPLTIihgnTDLLI 267
Cdd:PRK09303 100 QQEGATYSglgENLQPSEIDSGRYSQELLQLS--DELfvlrqENETLLEQlKFKDRVLAmLAHDLRTPLTA----ASLAL 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 268 E------INEN----PELLEYMEYISKGVTQ-IEKYINTLIDISKTENG-YILNKEAISMSEFIKDVLVQIEALASTKNL 335
Cdd:PRK09303 174 EtlelgqIDEDtelkPALIEQLQDQARRQLEeIERLITDLLEVGRTRWEaLRFNPQKLDLGSLCQEVILELEKRWLAKSL 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 336 DVEfykQD---NLPkNITIDRELLFRAIMNIISNAIDYSPSQSKlyISVSV-H--NKYLKFVVTDCGSGFSKADLSKATE 409
Cdd:PRK09303 254 EIQ---TDipsDLP-SVYADQERIRQVLLNLLDNAIKYTPEGGT--ITLSMlHrtTQKVQVSICDTGPGIPEEEQERIFE 327
|
250 260 270
....*....|....*....|....*....|..
gi 2053302028 410 QFYTgdLSR-NSKSHYGMGLYIVNNIVQKHNG 440
Cdd:PRK09303 328 DRVR--LPRdEGTEGYGIGLSVCRRIVRVHYG 357
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-460 |
5.07e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 51.00 E-value: 5.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 352 DRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNK-----YLKFVVTDCGSGFSKADLSKATEQFYTgdlsrNSKSHYGM 426
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGRPSDVGEVRIRVEadqdgRIVLIVCDNGKGFPREMRHRATEPYVT-----TRPKGTGL 75
|
90 100 110
....*....|....*....|....*....|....
gi 2053302028 427 GLYIVNNIVQKHNGTLCIENSvKTGGAMVTIEIP 460
Cdd:cd16944 76 GLAIVKKIMEEHGGRISLSNR-EAGGACIRIILP 108
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
248-460 |
1.01e-07 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 54.31 E-value: 1.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 248 LAHDIKTPLTII--HGNTDLLIEINENPE-LLEYMEYISKGVTQIEKYINTLIDISKTENGYIlnkEAISMSEFIKDVLV 324
Cdd:COG4192 440 LAHELNQPLNAMsmYLFSAKKALEQENYAqLPTSLDKIEGLIERMDKIIKSLRQFSRKSDTPL---QPVDLRQVIEQAWE 516
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 325 QIEALASTKNLdvefykQDNLPKNITI--DRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKA 402
Cdd:COG4192 517 LVESRAKPQQI------TLHIPDDLMVqgDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRVAISDNGNGWPLV 590
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2053302028 403 DlsKATEQFYTgdlsrnSKS-HYGMGLYIVNNIVQKHNGTLCIENSVkTGGAMVTIEIP 460
Cdd:COG4192 591 D--KLFTPFTT------TKEvGLGLGLSICRSIMQQFGGDLYLASTL-ERGAMVILEFN 640
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
356-460 |
1.14e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 49.88 E-value: 1.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 356 LFRAIMNIISNAIDYSPSQS-KLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTG-DLSRNSKSHYGMGLYIVNN 433
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDTgRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTErPANEAFGQHSGLGLSISRQ 80
|
90 100 110
....*....|....*....|....*....|
gi 2053302028 434 IVQKHNGTLCIENSVKTG---GAMVTIEIP 460
Cdd:cd16953 81 IIEAHGGISVAENHNQPGqviGARFTVQLP 110
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-446 |
2.39e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 49.43 E-value: 2.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 352 DRELLFRAIMNIISNAIDYSPSQSKLYISVSVHNKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNS-KSHYGMGLYI 430
Cdd:cd16947 17 NTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSRNSaKQGNGLGLTI 96
|
90
....*....|....*.
gi 2053302028 431 VNNIVQKHNGTLCIEN 446
Cdd:cd16947 97 TKRLAESMGGSIYVNS 112
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
360-459 |
7.68e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 47.45 E-value: 7.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 360 IMNIISNAIDYSPSQSKLYISVSVH--NKYLKFVVTDCGSGFSKADLSKATEQFYTgdlSRNSKSHYGMGLYIVNNIVQK 437
Cdd:cd16976 5 LMNLLQNALDAMGKVENPRIRIAARrlGGRLVLVVRDNGPGIAEEHLSRVFDPFFT---TKPVGKGTGLGLSISYGIVEE 81
|
90 100
....*....|....*....|..
gi 2053302028 438 HNGTLCIENSvKTGGAMVTIEI 459
Cdd:cd16976 82 HGGRLSVANE-EGAGARFTFDL 102
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
245-451 |
2.30e-06 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 50.29 E-value: 2.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 245 ISALAHDIKTPLTIIHGNTDLLIEINENPELLEYMEYISKGVTQIEKYINTLIDISKTENG---YILNKEAISMSEFIKD 321
Cdd:PRK11466 448 LAAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAGgknVSVSDEPFEPRPLLES 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 322 VLVQIEALASTKNLDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSpSQSKLYISVSVHNKYLKFVVTDCGSGFSK 401
Cdd:PRK11466 528 TLQLMSGRVKGRPIRLATDIADDLPTALMGDPRRIRQVITNLLSNALRFT-DEGSIVLRSRTDGEQWLVEVEDSGCGIDP 606
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2053302028 402 ADLSKATEQFYTGDLSRNSKshyGMGLYIVNNIVQKHNGTLCIENSVKTG 451
Cdd:PRK11466 607 AKLAEIFQPFVQVSGKRGGT---GLGLTISSRLAQAMGGELSATSTPEVG 653
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
311-461 |
2.58e-06 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 49.90 E-value: 2.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 311 EAISMSEFIKDVLVQIEALASTKNLDVEFykqdNLPkNITIDREllfRA-----IMN-IISNAIDY---SPSQSKLYISV 381
Cdd:COG3920 357 EGVDLRDYLRELLEPLRDSYGGRGIRIEL----DGP-DVELPAD---AAvplglILNeLVTNALKHaflSGEGGRIRVSW 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 382 SVHNKYLKFVVTDCGSGFSkADLSKATEQfytgdlsrnskshyGMGLYIVNNIVQKHNGTLCIENSvktGGAMVTIEIPI 461
Cdd:COG3920 429 RREDGRLRLTVSDNGVGLP-EDVDPPARK--------------GLGLRLIRALVRQLGGTLELDRP---EGTRVRITFPL 490
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
360-460 |
6.30e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 44.79 E-value: 6.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 360 IMNIISNAIDYSPSQSklyISVSVH-------NKYLKFVVTDCGSGFSKADLSKATEQFYTGDLSRNSKshY---GMGLY 429
Cdd:cd16922 5 LLNLLGNAIKFTEEGE---VTLRVSleeeeedGVQLRFSVEDTGIGIPEEQQARLFEPFSQADSSTTRK--YggtGLGLA 79
|
90 100 110
....*....|....*....|....*....|.
gi 2053302028 430 IVNNIVQKHNGTLCIEnSVKTGGAMVTIEIP 460
Cdd:cd16922 80 ISKKLVELMGGDISVE-SEPGQGSTFTFTLP 109
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
362-460 |
5.57e-05 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 45.67 E-value: 5.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 362 NIISNAIDYSPSQSKLYISVSVH--NKYLKFVVTDCGSGFSKADLSKATEQFYTgdlsrnSK-SHYGMGLYIVNNIVQKH 438
Cdd:PRK11086 440 NLIENALEAVGGEEGGEISVSLHyrNGWLHCEVSDDGPGIAPDEIDAIFDKGYS------TKgSNRGVGLYLVKQSVENL 513
|
90 100
....*....|....*....|..
gi 2053302028 439 NGTLCIEnSVKTGGAMVTIEIP 460
Cdd:PRK11086 514 GGSIAVE-SEPGVGTQFFVQIP 534
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
250-461 |
1.16e-04 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 44.58 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 250 HDIKTPLTIIHGNTDLLiEINENPE----LLEYMEYISKGVTQIekyINTLIDISKTENgyilNKEAISMSEFI-KDVLV 324
Cdd:PRK10841 456 HELRTPLYGIIGNLDLL-QTKELPKgvdrLVTAMNNSSSLLLKI---ISDILDFSKIES----EQLKIEPREFSpREVIN 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 325 QIEA----LASTKNLDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSkLYISVSVHNKYLKFVVTDCGSGFS 400
Cdd:PRK10841 528 HITAnylpLVVKKRLGLYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGC-IVLHVRVDGDYLSFRVRDTGVGIP 606
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2053302028 401 KADLSKATEQFYtgDLSRNSKSHY---GMGLYIVNNIVQKHNGTLCIEnSVKTGGAMVTIEIPI 461
Cdd:PRK10841 607 AKEVVRLFDPFF--QVGTGVQRNFqgtGLGLAICEKLINMMDGDISVD-SEPGMGSQFTIRIPL 667
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
359-454 |
1.55e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 41.21 E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 359 AIMNIISNAIDYSPSQSKLYISVS---------------VHNKYLKFVVTDCGSGFSKADLSKATEQFYTgdlSRNSKSH 423
Cdd:cd16919 4 AILNLAVNARDAMPEGGRLTIETSnqrvdadyalnyrdlIPGNYVCLEVSDTGSGMPAEVLRRAFEPFFT---TKEVGKG 80
|
90 100 110
....*....|....*....|....*....|.
gi 2053302028 424 YGMGLYIVNNIVQKHNGTLCIENSVKTGGAM 454
Cdd:cd16919 81 TGLGLSMVYGFVKQSGGHLRIYSEPGVGTTV 111
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
189-368 |
2.04e-04 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 43.95 E-value: 2.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 189 LKNTTEKIEQQDLDFVVESSKIYEINNVLFSMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIE 268
Cdd:COG2770 243 LAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLL 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 269 INENPELLEYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKNLDVEFYKQDNLPKN 348
Cdd:COG2770 323 LAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAAL 402
|
170 180
....*....|....*....|
gi 2053302028 349 ITIDRELLFRAIMNIISNAI 368
Cdd:COG2770 403 LLLELALEELVLALLALALL 422
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
246-461 |
4.25e-04 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 42.74 E-value: 4.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 246 SALAHDIKTPLTIIHGNTdlliEINEN-----PELLEYMEYISKGVTQIEKYINTLIDISKTENGyilNKEAISMSEFIK 320
Cdd:PRK13837 455 SGIAHNFNNILGAILGYA----EMALNklarhSRAARYIDEIISAGARARLIIDQILAFGRKGER---NTKPFDLSELVT 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 321 DVLVQIEA-LASTKNLDVefyKQDNLPKNITIDRELLFRAIMNIISNA---------IDYSPSQSKLYISVSVHN----- 385
Cdd:PRK13837 528 EIAPLLRVsLPPGVELDF---DQDQEPAVVEGNPAELQQVLMNLCSNAaqamdgagrVDISLSRAKLRAPKVLSHgvlpp 604
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2053302028 386 -KYLKFVVTDCGSGFSKADLSKATEQFYTgdlSRNSKShyGMGLYIVNNIVQKHNGtlCIENSVKTG-GAMVTIEIPI 461
Cdd:PRK13837 605 gRYVLLRVSDTGAGIDEAVLPHIFEPFFT---TRAGGT--GLGLATVHGIVSAHAG--YIDVQSTVGrGTRFDVYLPP 675
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
326-461 |
1.93e-03 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 39.99 E-value: 1.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2053302028 326 IEALASTKNLDVEFyKQDNLPKNITIDREL-LFRAIMNIISNAIDYSPSqSKLYISVSVHNKYLKFVVTDCGSGFSKADL 404
Cdd:COG4585 133 AERLLRAAGIRVEL-DVDGDPDRLPPEVELaLYRIVQEALTNALKHAGA-TRVTVTLEVDDGELTLTVRDDGVGFDPEAA 210
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2053302028 405 SKAteqfytgdlsrnskshyGMGLYIVNNIVQKHNGTLCIEnSVKTGGAMVTIEIPI 461
Cdd:COG4585 211 PGG-----------------GLGLRGMRERAEALGGTLTIG-SAPGGGTRVRATLPL 249
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-460 |
6.84e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 36.15 E-value: 6.84e-03
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gi 2053302028 362 NIISNAIDYSPSQSKLYISVS---VHNKYLkFVVTDCGSGFSKADLSKATEQFYTGDlSRNSKSHYGMGLYIVNNIVQKH 438
Cdd:cd16921 7 NLLGNAIKFRRPRRPPRIEVGaedVGEEWT-FYVRDNGIGIDPEYAEKVFGIFQRLH-SREEYEGTGVGLAIVRKIIERH 84
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90 100
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gi 2053302028 439 NGTLCIENSVkTGGAMVTIEIP 460
Cdd:cd16921 85 GGRIWLESEP-GEGTTFYFTLP 105
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