|
Name |
Accession |
Description |
Interval |
E-value |
| Phage_lysozyme2 |
pfam18013 |
Phage tail lysozyme; This domain has a lysozyme like fold. It is found in the tail protein of ... |
1735-1866 |
1.52e-43 |
|
Phage tail lysozyme; This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.
Pssm-ID: 465617 Cd Length: 139 Bit Score: 155.92 E-value: 1.52e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1735 TQAKVWNFFKSKGLSDHAVAGIMGNMERESRFKPGAQEQ---GGTGIGLVQLSFGRANNLRNYAARRGKSWKDLNTQLDF 1811
Cdd:pfam18013 2 NAKAIYNFLKSKGYSKAAAAGILGNMQRESGFNPGAVEDeggGGGGYGLVQWTGGRKTALINFAKAKGKSWSDLDAQLDF 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2071643352 1812 IWKELNT-TEVNALRGLKSATSVIGAANSFQRLYERAGV--VAQGERNAAAKKYYRQF 1866
Cdd:pfam18013 82 LDKELNNsTYKAAKKKLKSATSPEEAAKAFLRYYERPGVkdAKLEERGAYAQKWYDKF 139
|
|
| tape_meas_TP901 |
TIGR01760 |
phage tail tape measure protein, TP901 family, core region; This model represents a reasonably ... |
414-761 |
8.97e-38 |
|
phage tail tape measure protein, TP901 family, core region; This model represents a reasonably well conserved core region of a family of phage tail proteins. The member from phage TP901-1 was characterized as a tail length tape measure protein in that a shortened form of the protein leads to phage with proportionately shorter tails. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 273790 [Multi-domain] Cd Length: 350 Bit Score: 146.73 E-value: 8.97e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 414 FFGAINGAKEMLDVITEIDGKMITLAKVTGDDNALQqtFIDANNAASQFGQTL----GSVLDVYAEFARQGVKGNELSQF 489
Cdd:TIGR01760 1 SAALGGGLVAAVKAAIEFEDAMSGVRAVVDGSRTKE--FEDLSNQARDLGDETpfsaAQIAGAMTALARAGISAKDLLGA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 490 SNAALIAANVGEIDAKQASEYLTSMSAQWETTGNQAMRQVDSLNEVSNKYATTVEKLAQGQAKAGSTAKSMGLTFDETNG 569
Cdd:TIGR01760 79 TPTALKLAAASDLTAEEAASILAKIMNAFGLTAKDSEKVADVLNYTANNSAATTRDMGDALQYAGPVAKSLGVSLEETAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 570 IIGALtAKTKQSGDEIGNFMKATLPKLY--SGKGKSTIEGLGISMKDENGQLKSAISLLEEVSQKTKNLEKDQKAAVING 647
Cdd:TIGR01760 159 ATAAL-ASAGIEGEIAGTALKAMLSRLAapTGKAAKALKKLGIQTRDAKGNMKGLLDVLKELQKLTKGMGTEQQAAKLKT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 648 LGGTYHYQRMQVLlddLSKTDGLYKQIKESSESSAGSALQENA-KYMESIEAKVNQAKTAFEQFALAVGETFAKSGMlDG 726
Cdd:TIGR01760 238 IFGVEASSALATL---LTAGSKLSLAKNAKSLANSNGSAKKEAdKMLDTLKGQLKLLQNAVENAFIELGEALLPALR-EL 313
|
330 340 350
....*....|....*....|....*....|....*
gi 2071643352 727 IRMVTQLLTGLTHGITELGTTAPIFGMVGGAASLM 761
Cdd:TIGR01760 314 AQALTKLINAINGLAKGNPQLAVTLAAVAAAILAL 348
|
|
| PhageMin_Tail |
pfam10145 |
Phage-related minor tail protein; Members of this family are found in putative phage tail tape ... |
456-650 |
2.25e-30 |
|
Phage-related minor tail protein; Members of this family are found in putative phage tail tape measure proteins.
Pssm-ID: 462962 [Multi-domain] Cd Length: 201 Bit Score: 120.48 E-value: 2.25e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 456 NNAASQFGQTLG----SVLDVYAEFARQGVKGNELSQFSNAALIAANVGE-IDAKQASEYLTSMSAQWETTGNQAMRQVD 530
Cdd:pfam10145 1 RDAALELGETTGfsatDAAEAMAALASAGLSAEELLSATEGALKLAVAGGaTDAAEAAEALAAAMNAFGLSADDAEEAAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 531 SLNEVSNKYATTVEKLAQGQAKAGSTAKSMGLTFDETNGIIGALTAKTkQSGDEIGNFMKATLPKLY--SGKGKSTIEGL 608
Cdd:pfam10145 81 VLAAAANNGATEVGDLADALKEVGPVAKAAGLSGEETAAALALLAAAG-ISGSEAGTALKNFLTRLAapTKEAAKALKKL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2071643352 609 GISMKDENGQLKSAISLLEEVSQKTKNLEKDQKAAVINGLGG 650
Cdd:pfam10145 160 GISAKDANGKMKSLSEILEELAQALKGLTDAQRAAALSALFG 201
|
|
| NlpD |
COG0739 |
Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell ... |
1899-2028 |
5.22e-26 |
|
Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440502 [Multi-domain] Cd Length: 196 Bit Score: 107.75 E-value: 5.22e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1899 DRQFGRYNGGGVHHGRDITSATinGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKNTYT-YMHMKNPArVVKGQRVKAGQ 1976
Cdd:COG0739 85 YRRHPVTGRRRFHKGIDIAAPT--GTPVYAAADGTVVFAGWNGGyGNLVIIDHGNGYTTlYAHLSSIL-VKVGQRVKAGQ 161
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2071643352 1977 IVGNVGTThdrrlgGFSTGPHLHVQVNLgktpsgtfmntfNGahRAVDPVKY 2028
Cdd:COG0739 162 VIGYVGNT------GRSTGPHLHFEVRV------------NG--KPVDPLPF 193
|
|
| M23_peptidase |
cd12797 |
M23 family metallopeptidase, also known as beta-lytic metallopeptidase, and similar proteins; ... |
1911-2002 |
2.51e-25 |
|
M23 family metallopeptidase, also known as beta-lytic metallopeptidase, and similar proteins; This model describes the metallopeptidase M23 family, which includes beta-lytic metallopeptidase and lysostaphin. Members of this family are zinc endopeptidases that lyse bacterial cell wall peptidoglycans; they cleave either the N-acylmuramoyl-Ala bond between the cell wall peptidoglycan and the cross-linking peptide (e.g. beta-lytic endopeptidase) or a bond within the cross-linking peptide (e.g. stapholysin, and lysostaphin). Beta-lytic metallopeptidase, formerly known as beta-lytic protease, has a preference for cleavage of Gly-X bonds and favors hydrophobic or apolar residues on either side. It inhibits growth of sensitive organisms and may potentially serve as an antimicrobial agent. Lysostaphin, produced by Staphylococcus genus, cleaves pentaglycine cross-bridges of cell wall peptidoglycan, acting as autolysins to maintain cell wall metabolism or as toxins and weapons against competing strains. Staphylolysin (also known as LasA) is implicated in a range of processes related to Pseudomonas virulence, including stimulating shedding of the ectodomain of cell surface heparan sulphate proteoglycan syndecan-1, and elastin degradation in connective tissue. Its active site is less constricted and contains a five-coordinate zinc ion with trigonal bipyramidal geometry and two metal-bound water molecules, possibly contributing to its activity against a wider range of substrates than those used by related lytic enzymes, consistent with its multiple roles in Pseudomonas virulence. The family includes members that do not appear to have the conserved zinc-binding site and might be lipoproteins lacking proteolytic activity.
Pssm-ID: 410984 [Multi-domain] Cd Length: 85 Bit Score: 101.51 E-value: 2.51e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1911 HHGRDItsATINGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKNTYT-YMHMKNPArVVKGQRVKAGQIVGNVGTThdrr 1988
Cdd:cd12797 1 HNGIDI--AAPEGTPVYAAADGTVVFAGWDGGyGNYVIIDHGNGYYTlYAHLSSIL-VKVGQRVKKGQVIGTVGNT---- 73
|
90
....*....|....
gi 2071643352 1989 lgGFSTGPHLHVQV 2002
Cdd:cd12797 74 --GRSTGPHLHFEI 85
|
|
| COG5283 |
COG5283 |
Phage-related tail protein [Mobilome: prophages, transposons]; |
323-777 |
6.21e-24 |
|
Phage-related tail protein [Mobilome: prophages, transposons];
Pssm-ID: 444094 [Multi-domain] Cd Length: 747 Bit Score: 110.33 E-value: 6.21e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 323 ALTSQIERIENRMAATID-----KQQTNALKNQLNSLGNNRTPFG---KEAAFHMNQIQDKVRQISAEAERATR------ 388
Cdd:COG5283 25 ALAQALKALEAPTRALARaleraKQAAARLQTKYNKLRQSLQRLRqalDQAGIDTRQLSAAQRRLRSSLEQTNRqlerqq 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 389 TQLSFVDQFREAMTKFPVWM--GATTLFFGAINGAKEMLDVITEID--GKMITLAKVTGDDN---ALQQTFIDANNAASQ 461
Cdd:COG5283 105 QRLARLGARQDRLKAARARLqrLAGAGAAAAAIGAALAASVKPAIDfeDAMADVAATVDLDKsseQFKALGKQARELSAQ 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 462 FGQTLGSVLDVYAEFARQGVKGNELSQFSNAALIAANVGEIDAKQASEYLTSMSAQWETTGNQAMRQVDSLNEVSNKYAT 541
Cdd:COG5283 185 TPQSADDIAAGQAALAQAGVSAEDILAFTPTAAKLATAFDTDAEEAAEIAAKILNAFKLPADDVERLGDALNYAGNNGAT 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 542 TVEKLAQGQAKAGSTAKSMGLTFDETNGIIGALtAKTKQSGDEIGNFMKATLPKLYSGKGKST--IEGLGISMKDENGQL 619
Cdd:COG5283 265 SLADLADALPYVGPVAKALGVSGKEAAALGAAL-ADAGIEGEEAGTALRNMLTRLTSPTKAAAkaLKKLGIDTQDSKGNL 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 620 KSAISLLE------------EVSQKTKNLEKDQKAAVINGLGGTyhyQRMQVLLDDLSKTDGLYKQIKESSESSAGSALQ 687
Cdd:COG5283 344 RGLAKILAkqmqkdaqgalaELLKALKKLDAAKRAAALKQLFGE---EAVSALAPLLQNGDELRKQLAVAEAAAAQGSMD 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 688 -ENAKYMESIEAKVNQAKTAFEQFALAVGETFAKS---------GMLDGIRMVTQLLTGLTHGITELGTTAPIFGMVGGA 757
Cdd:COG5283 421 kEAAKRTDTLAGQLKLLKNALENLGISIGEALLPAlrelaqaltPVVGKLADWAKANPGLIKTIVKVAAALAGLKAALGA 500
|
490 500
....*....|....*....|
gi 2071643352 758 ASLMSKNVRSGFEGARSSVA 777
Cdd:COG5283 501 LRLALALLLSPLAALKAAAA 520
|
|
| Peptidase_M23 |
pfam01551 |
Peptidase family M23; Members of this family are zinc metallopeptidases with a range of ... |
1909-2008 |
5.38e-23 |
|
Peptidase family M23; Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins such as Swiss:P33648 for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.
Pssm-ID: 460250 [Multi-domain] Cd Length: 96 Bit Score: 95.31 E-value: 5.38e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1909 GVHHGRDItsATINGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKNTYT-YMHMKNpARVVKGQRVKAGQIVGNVGTThd 1986
Cdd:pfam01551 1 RFHKGIDI--AAPTGTPVYAAADGVVVFAGWLGGyGNLVIIDHGNGYSTlYAHLSS-ILVKVGQRVKAGQVIGTVGST-- 75
|
90 100
....*....|....*....|..
gi 2071643352 1987 rrlgGFSTGPHLHVQVNLGKTP 2008
Cdd:pfam01551 76 ----GRSTGPHLHFEIRKNGKP 93
|
|
| YqbO |
COG5280 |
Phage-related minor tail protein [Mobilome: prophages, transposons]; |
433-1289 |
1.49e-21 |
|
Phage-related minor tail protein [Mobilome: prophages, transposons];
Pssm-ID: 444091 [Multi-domain] Cd Length: 962 Bit Score: 103.08 E-value: 1.49e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 433 GKMITLAKVTGDD-NALQQTFIDANNAasqFGQTLGSVLDVYAEFARQGVKGNELSQFSNAALIAANVGEIDAKQASEYL 511
Cdd:COG5280 78 STVQAVTGATGEElEALEQLAKELGAT---TGESAAEVAEALGSVAQAGLSGDELIAVTEGALVLAAATGVDLNEAAEIV 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 512 TSMSAQWETTGNQAMRQVDSLNEVSNKYATTVEKLAQGQAKAGSTAKSMGLTFDETNGIIGALTAKTKQsGDEIGNFMKA 591
Cdd:COG5280 155 ASAMNAFGLSADEASRVADLLAAGAQAGNTTSDELADALKEYAPLAAALGFSLEETLAALALLANAGIK-GSDAGTALKE 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 592 TLPKLYSGKGKS--TIEGLGISMKDENGQLKSAISLLEEVSQKTKNLEKDQKAAVINGLGGTyhyQRMQVLLDDLSKTDG 669
Cdd:COG5280 234 FLIRLADPSKTAaeALEELGINVFDASGKLKGLSEILGELAKKFAGLGEAARAAVLAAIFGD---DAGRAAIALLLFGTD 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 670 LYKQIKESSESSAGSALQENAKYMESIEAKVNQAKTAFEQFALAVGETF------AKSGMLDGIRMVTQLLTGLTHGITE 743
Cdd:COG5280 311 WYAKLTAALKNSAGAADEAAATMQDNLAGALESLKSALEGLAITIGETLlpalrdAVEALTGLADWFNELSPAVQELIIA 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 744 LGTTAPIFG---MVGGAASLMSKNVRSGFEGARSSVANYITEVnkLAK-VNNAAGQVVGLqkvqtGTASQLQFNKNGEYD 819
Cdd:COG5280 391 IAGLVAALGpllLILGALITGIGALAGAFGILSTALAKAKGAL--LAGpIGIVIAAIAAL-----AAALVLLYKNWDTIK 463
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 820 KAASQakaaeqaTYQFSKAQKDVSASAMiasgainkttvattastvaTRAATLAVNGLKLAFRGLLAATGVGLAITGVSF 899
Cdd:COG5280 464 EFLTG-------LWNSIKEAIGGVWDGI-------------------KTSVEGLKGAAGAALSAAAGKAIEALAGISVDA 517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 900 VLEKVVGSFNAASQAAEQYKQKQEQTKQAIASMSNGEINSLISSYDKLQQKMNSGSAFNTAEAEKYKEVTSQLANIFPDL 979
Cdd:COG5280 518 LKQGVILSGTISMLWGAAGTEVSLKGGAAQDNVSDAASSAGDGALAIINSAEQAIIGLAAALKTASTSSALQASTKAAAA 597
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 980 VTGENRYG-KEMAGNKEVMKQKIELIKQemeLERQKNAIKQKEEQDAYIKEQDSLAKKNRGQKWYQLGQTPELKLQEQAR 1058
Cdd:COG5280 598 TKAEKTILaIAMATVKGVTSATAALANA---AGVILQGAIKNGISGALDSAGATTVAKLAEEEAINEKIVELLKAAANGA 674
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1059 PTTVSDNSNiNKINATIQKVKSQAQAEKALEQVDKQLAQSQTKNRQNevqhLQKVRQALQDYITKTGQANQATRAAVLTA 1138
Cdd:COG5280 675 NKEAVANAL-LLDAAAKQNINGQEAILEGITAKGVQTDELQDSDAIQ----AKFQFEELSEGAKATINAINGNGVLGGII 749
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1139 QQQFTNQIATMKKLGTtgqqVMTTISNSVAKtaksgKAAQATFKSFETSLVKSSSFKSKMASYEasVKKFKNAANQSAKI 1218
Cdd:COG5280 750 ADGIKTNSAELKAAAN----ELKGDINRVAA-----AINSLAEAGAEEIKSEAKEAGSDKAITG--EAGQAALELAVARV 818
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2071643352 1219 AALKDVERDYSKVAKGIMQAAKAANMSKSQMKDLKKSLQQNIQAETGFRA--SVSKAGKVTIDQSKKIKQNTA 1289
Cdd:COG5280 819 NALISRVTKNITGTLSGSTVSILKGNTTEIENASKKITESGDKIMTGKDIelLAEGEFAVLIKNVKANGGNIA 891
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2060-2588 |
1.72e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.01 E-value: 1.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2060 AEDLNEAEQERlnKIEQAinahNKAEEMKqKVDELRKTLMDKQLEEVQTAKEKSENLYNIQKSH-VEEYDHWRTLQEARS 2138
Cdd:PTZ00121 1190 AEELRKAEDAR--KAEAA----RKAEEER-KAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEeERNNEEIRKFEEARM 1262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2139 AKLEYELNKIEFEKGRNTKEWRnKNKQLQASRQLEVNFEDSKIQYINKAL--KKNANKIFGKNTVNRDEFETMKRDAQQn 2216
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARKADELK-KAEEKKKADEAKKAEEKKKADEAKKKAeeAKKADEAKKKAEEAKKKADAAKKKAEE- 1340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2217 irdlkagiQTASGEIATSMIDQILDEYEDRVGKVSAKIEKMGKQKEKLDladnkqALKSSSLSRQQAKDSKSLASYINFY 2296
Cdd:PTZ00121 1341 --------AKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD------AAKKKAEEKKKADEAKKKAEEDKKK 1406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2297 IKQLERQLKLTGKNHELQQKVKEQIKemkvayddatlaAHQYITEAAEVDTERQLQLNANRLRDAQNELSKADYKAGFIS 2376
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKK------------ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2377 QEYQIDLYRKNQEAKFKGYLKEKEALEQNKSELQDMYEIYKSVPTQAQKIKEAL-IETKNAIRDNNKGLYDLKYDMANSV 2455
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKkAEEAKKADEAKKAEEKKKADELKKA 1554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2456 INQIKDIYSKQLEVATKAYDDEYKAYEKMinKKLKLIDDEQTQESFNKDVRDRTEAMDKIRDEIAQRSGDDSLANQKKLK 2535
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKA--EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 2071643352 2536 DLREQLKQQEEDYTMFINN-KNRDDRRKALQDELNDKNEQIQEQKEDLNKAFQD 2588
Cdd:PTZ00121 1633 KKVEQLKKKEAEEKKKAEElKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED 1686
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
2236-2660 |
2.60e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 56.67 E-value: 2.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2236 IDQILDEYEDRVGKVSAKIEKMGKQKEK---------LDLADNKQALKS-----SSLSRQQAKDSKSLASYINFYIKQLE 2301
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELHEKqkfylrqsvIDLQTKLQEMQMerdamADIRRRESQSQEDLRNQLQNTVHELE 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2302 --RQLK---LTGKNHELQQKVKEQI------KEMKVAYDDATLAAHQYITEAAEVDTE--RQLQLNANR-LRDAQNELSK 2367
Cdd:pfam15921 156 aaKCLKedmLEDSNTQIEQLRKMMLshegvlQEIRSILVDFEEASGKKIYEHDSMSTMhfRSLGSAISKiLRELDTEISY 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2368 adYKAGFISQEYQIDLYRKNQEAKFKGYLKE-----KEALEQNKSELQDMYEIYKSVPTQAQKIKEALIETKNAIRDNNk 2442
Cdd:pfam15921 236 --LKGRIFPVEDQLEALKSESQNKIELLLQQhqdriEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN- 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2443 GLYDLKYDMANSVINQIKdiysKQLEVATKAYDDEYKAYEKminkKLKLIDDEQTQEsfnkdvrdRTEamdkiRDEIAQR 2522
Cdd:pfam15921 313 SMYMRQLSDLESTVSQLR----SELREAKRMYEDKIEELEK----QLVLANSELTEA--------RTE-----RDQFSQE 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2523 SG--DDSLanQKKLKDLREQLK----QQEEDYTMFINNKNRDDRRKALQDELNDKNEQIQEQKEDLNKAFQDLIGDT-RR 2595
Cdd:pfam15921 372 SGnlDDQL--QKLLADLHKREKelslEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMeRQ 449
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2071643352 2596 FNAIQ---ESLmegqiDKYKSLIADLtkyvnDNMKEIGRSTSEGILDG---LAASFKGLSSLSKELQKQEK 2660
Cdd:pfam15921 450 MAAIQgknESL-----EKVSSLTAQL-----ESTKEMLRKVVEELTAKkmtLESSERTVSDLTASLQEKER 510
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
901-1273 |
2.86e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.14 E-value: 2.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 901 LEKVVGSFNAASQAAEQYKQKQEQTKQAIASMSNGEINSLISSYDKLQQKMNsgsafntAEAEKYKEVTSQLANIFPDLV 980
Cdd:TIGR02168 198 LERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELK-------EAEEELEELTAELQELEEKLE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 981 TGENRygkemagnKEVMKQKIELIKQemELERQKNAIKQKEEQDAYIKEQDSLAKKNRGQKWYQLGQTPELKLQEQARPT 1060
Cdd:TIGR02168 271 ELRLE--------VSELEEEIEELQK--ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1061 TVSDnsNINKINATIQKVKSQAQAEKALEQVDKQLAQSQTKNRQNEVQHLQKVRQALQDyITKTGQANQATRAAVLTAQQ 1140
Cdd:TIGR02168 341 ELEE--KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS-LNNEIERLEARLERLEDRRE 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1141 QFTNQIATMKKLGTTGQqvMTTISNSVAKTAKSGKAAQATFKSFETSLvksSSFKSKMASYEASVKKFKNAANQ-SAKIA 1219
Cdd:TIGR02168 418 RLQQEIEELLKKLEEAE--LKELQAELEELEEELEELQEELERLEEAL---EELREELEEAEQALDAAERELAQlQARLD 492
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2071643352 1220 ALKDVERDYSKVAKGImqaaKAANMSKSQMKDLKKSLQQNIQAETGFRASVSKA 1273
Cdd:TIGR02168 493 SLERLQENLEGFSEGV----KALLKNQSGLSGILGVLSELISVDEGYEAAIEAA 542
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2240-2621 |
3.90e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.76 E-value: 3.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2240 LDEYEDRVGKVSAKIEKMGKQKEKL-----------DLADNKQALKSSSLSRQQAKDSKSLA------SYINFYIKQLER 2302
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERLrrerekaeryqALLKEKREYEGYELLKEKEALERQKEaierqlASLEEELEKLTE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2303 QLKLTGKN-HELQQKVKEQIKEMKVAYDDATLAAHQYI--TEAAEVDTERQLQLNANRLRDAQNELSKADYKAGfiSQEY 2379
Cdd:TIGR02169 259 EISELEKRlEEIEQLLEELNKKIKDLGEEEQLRVKEKIgeLEAEIASLERSIAEKERELEDAEERLAKLEAEID--KLLA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2380 QIDLYRKNQEAkfkgYLKEKEALEQNKSELQDMYEIYKSvptQAQKIKEALIETKNAIRDnnkglYDLKYDMANSVINQI 2459
Cdd:TIGR02169 337 EIEELEREIEE----ERKRRDKLTEEYAELKEELEDLRA---ELEEVDKEFAETRDELKD-----YREKLEKLKREINEL 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2460 KDIYSKQLEVATKAYDDEYKayekmINKKLKLIDDEQTQesFNKDVRDRTEAMDKIRDEIAQrsgddslaNQKKLKDLRE 2539
Cdd:TIGR02169 405 KRELDRLQEELQRLSEELAD-----LNAAIAGIEAKINE--LEEEKEDKALEIKKQEWKLEQ--------LAADLSKYEQ 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2540 QLKQQEEDYtmfinnknrddrrKALQDELNDKNEQIQEQkedlnKAFQDLIGDTRRFNAIQESLMEGQIDKYKSLIADLT 2619
Cdd:TIGR02169 470 ELYDLKEEY-------------DRVEKELSKLQRELAEA-----EAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531
|
..
gi 2071643352 2620 KY 2621
Cdd:TIGR02169 532 SV 533
|
|
| PRK11649 |
PRK11649 |
putative peptidase; Provisional |
1911-2002 |
2.71e-05 |
|
putative peptidase; Provisional
Pssm-ID: 236946 [Multi-domain] Cd Length: 439 Bit Score: 49.28 E-value: 2.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1911 HHGRDItsATINGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKnTYT--YMHMKNpaRVVK-GQRVKAGQIVGNVGTThd 1986
Cdd:PRK11649 313 HRGVDF--AMPVGTPVLAVGDGEVVVAKRSGAaGNYVAIRHGR-QYTtrYMHLRK--LLVKpGQKVKRGDRIALSGNT-- 385
|
90
....*....|....*.
gi 2071643352 1987 rrlgGFSTGPHLHVQV 2002
Cdd:PRK11649 386 ----GRSTGPHLHYEV 397
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2213-2541 |
2.03e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2213 AQQNIRDLKAGIQTASGEIAT--------SMIDQiLDEYEDRVGKVSAKIEKMGKQKEKLDLADNK-QALKssslsrQQA 2283
Cdd:COG4913 622 LEEELAEAEERLEALEAELDAlqerrealQRLAE-YSWDEIDVASAEREIAELEAELERLDASSDDlAALE------EQL 694
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2284 KDSKSLasyinfyIKQLERQL-KLTGKNHELQQKVK---EQIKEMKVAYDDATLAAHQYITEAAE--------------- 2344
Cdd:COG4913 695 EELEAE-------LEELEEELdELKGEIGRLEKELEqaeEELDELQDRLEAAEDLARLELRALLEerfaaalgdaverel 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2345 -VDTERQLQLNANRLRDAQNELSKA--DYKA--GFISQEYQIDL-----YRK-----------NQEAKFKGYLKEKEalE 2403
Cdd:COG4913 768 rENLEERIDALRARLNRAEEELERAmrAFNRewPAETADLDADLeslpeYLAlldrleedglpEYEERFKELLNENS--I 845
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2404 QNKSELQdmyeiyksvptqaQKIKEALIETKNAIRDNNKGLYDLKYDmANSVInqikdiyskQLEvATKAYDDEYKAYEK 2483
Cdd:COG4913 846 EFVADLL-------------SKLRRAIREIKERIDPLNDSLKRIPFG-PGRYL---------RLE-ARPRPDPEVREFRQ 901
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2071643352 2484 MINKKLK---LIDDEQTQESFnkdvrdrtEAMDKIRDEIAQRSGDDSLANQKKLKDLREQL 2541
Cdd:COG4913 902 ELRAVTSgasLFDEELSEARF--------AALKRLIERLRSEEEESDRRWRARVLDVRNHL 954
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
998-1157 |
5.12e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.59 E-value: 5.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 998 KQKIELIKQEMELERQKNAIKQKEEQdayikEQDSLAKKNRGQKwyqlgQTPELKLQ-EQARPTTVSDNSNINKINATIQ 1076
Cdd:PRK11281 42 QAQLDALNKQKLLEAEDKLVQQDLEQ-----TLALLDKIDRQKE-----ETEQLKQQlAQAPAKLRQAQAELEALKDDND 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1077 KVKSQAQAEKALEQVDKQLAQsqtknRQNEvqhLQKVRQALQDYITK-TGQANQATRA-AVLTAQQQFTNQIATMKKLGT 1154
Cdd:PRK11281 112 EETRETLSTLSLRQLESRLAQ-----TLDQ---LQNAQNDLAEYNSQlVSLQTQPERAqAALYANSQRLQQIRNLLKGGK 183
|
...
gi 2071643352 1155 TGQ 1157
Cdd:PRK11281 184 VGG 186
|
|
| MARTX_Nterm |
NF012221 |
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ... |
1048-1332 |
5.83e-03 |
|
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.
Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 42.51 E-value: 5.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1048 TPELKLQEQARPTTVSDNSNINkiNATIQKVKSQAQAEKALEQVDKQLAQSQTKNRQNEVQHLQKVrqalqdyitktGQA 1127
Cdd:NF012221 1537 TSESSQQADAVSKHAKQDDAAQ--NALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNAL-----------ETN 1603
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1128 NQATRAAVLTAQQQFTNQIATMKklgttgqQVMTTISNSVAKTAKSGKA-----AQATFKSFETSLVKSSSFKSKM---- 1198
Cdd:NF012221 1604 GQAQRDAILEESRAVTKELTTLA-------QGLDALDSQATYAGESGDQwrnpfAGGLLDRVQEQLDDAKKISGKQlada 1676
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1199 -ASYEASVKKFKNAANQSAkiAALKDVERDYSKVAKGIMQAAKAANMSKSQMKDLKKSLQqniQAETGFRASVSKAgkvt 1277
Cdd:NF012221 1677 kQRHVDNQQKVKDAVAKSE--AGVAQGEQNQANAEQDIDDAKADAEKRKDDALAKQNEAQ---QAESDANAAANDA---- 1747
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2071643352 1278 idqsKKIKQNTAETRRNSSAKLQNADASDQASEENKeladSMRAGIESSQLLGKA 1332
Cdd:NF012221 1748 ----QSRGEQDASAAENKANQAQADAKGAKQDESDK----PNRQGAAGSGLSGKA 1794
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
6-260 |
6.49e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 42.35 E-value: 6.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 6 NIGILSTLEIDSSSSRKKINDTLKNIEANINSIKADLEVSDTKKSENNAIKSANNVIRNINSN-GNLkkLNVELDVNlTK 84
Cdd:TIGR01612 950 NIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKDASLNDYEAKNNELIKYFNDLKANLGKNkENM--LYHQFDEK-EK 1026
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 85 SRQNIQRALSTLSKDFKNKKIDIEVNAkanKNSIGQVKNSISKGAS--QPLEIKESPSSRSTSRDIKEQQSLMtglansy 162
Cdd:TIGR01612 1027 ATNDIEQKIEDANKNIPNIEIAIHTSI---YNIIDEIEKEIGKNIEllNKEILEEAEINITNFNEIKEKLKHY------- 1096
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 163 kNLDDLTRALNTSTFEGLRKTVKEIKNADNSLKSYQVTLERVNQEGKKLgsqrfdytpsANGLKLNKTQLTDQTDKARKE 242
Cdd:TIGR01612 1097 -NFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENY----------IDEIKAQINDLEDVADKAISN 1165
|
250
....*....|....*....
gi 2071643352 243 ENA-AINKLLENEVSKYDR 260
Cdd:TIGR01612 1166 DDPeEIEKKIENIVTKIDK 1184
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Phage_lysozyme2 |
pfam18013 |
Phage tail lysozyme; This domain has a lysozyme like fold. It is found in the tail protein of ... |
1735-1866 |
1.52e-43 |
|
Phage tail lysozyme; This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.
Pssm-ID: 465617 Cd Length: 139 Bit Score: 155.92 E-value: 1.52e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1735 TQAKVWNFFKSKGLSDHAVAGIMGNMERESRFKPGAQEQ---GGTGIGLVQLSFGRANNLRNYAARRGKSWKDLNTQLDF 1811
Cdd:pfam18013 2 NAKAIYNFLKSKGYSKAAAAGILGNMQRESGFNPGAVEDeggGGGGYGLVQWTGGRKTALINFAKAKGKSWSDLDAQLDF 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2071643352 1812 IWKELNT-TEVNALRGLKSATSVIGAANSFQRLYERAGV--VAQGERNAAAKKYYRQF 1866
Cdd:pfam18013 82 LDKELNNsTYKAAKKKLKSATSPEEAAKAFLRYYERPGVkdAKLEERGAYAQKWYDKF 139
|
|
| tape_meas_TP901 |
TIGR01760 |
phage tail tape measure protein, TP901 family, core region; This model represents a reasonably ... |
414-761 |
8.97e-38 |
|
phage tail tape measure protein, TP901 family, core region; This model represents a reasonably well conserved core region of a family of phage tail proteins. The member from phage TP901-1 was characterized as a tail length tape measure protein in that a shortened form of the protein leads to phage with proportionately shorter tails. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 273790 [Multi-domain] Cd Length: 350 Bit Score: 146.73 E-value: 8.97e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 414 FFGAINGAKEMLDVITEIDGKMITLAKVTGDDNALQqtFIDANNAASQFGQTL----GSVLDVYAEFARQGVKGNELSQF 489
Cdd:TIGR01760 1 SAALGGGLVAAVKAAIEFEDAMSGVRAVVDGSRTKE--FEDLSNQARDLGDETpfsaAQIAGAMTALARAGISAKDLLGA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 490 SNAALIAANVGEIDAKQASEYLTSMSAQWETTGNQAMRQVDSLNEVSNKYATTVEKLAQGQAKAGSTAKSMGLTFDETNG 569
Cdd:TIGR01760 79 TPTALKLAAASDLTAEEAASILAKIMNAFGLTAKDSEKVADVLNYTANNSAATTRDMGDALQYAGPVAKSLGVSLEETAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 570 IIGALtAKTKQSGDEIGNFMKATLPKLY--SGKGKSTIEGLGISMKDENGQLKSAISLLEEVSQKTKNLEKDQKAAVING 647
Cdd:TIGR01760 159 ATAAL-ASAGIEGEIAGTALKAMLSRLAapTGKAAKALKKLGIQTRDAKGNMKGLLDVLKELQKLTKGMGTEQQAAKLKT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 648 LGGTYHYQRMQVLlddLSKTDGLYKQIKESSESSAGSALQENA-KYMESIEAKVNQAKTAFEQFALAVGETFAKSGMlDG 726
Cdd:TIGR01760 238 IFGVEASSALATL---LTAGSKLSLAKNAKSLANSNGSAKKEAdKMLDTLKGQLKLLQNAVENAFIELGEALLPALR-EL 313
|
330 340 350
....*....|....*....|....*....|....*
gi 2071643352 727 IRMVTQLLTGLTHGITELGTTAPIFGMVGGAASLM 761
Cdd:TIGR01760 314 AQALTKLINAINGLAKGNPQLAVTLAAVAAAILAL 348
|
|
| PhageMin_Tail |
pfam10145 |
Phage-related minor tail protein; Members of this family are found in putative phage tail tape ... |
456-650 |
2.25e-30 |
|
Phage-related minor tail protein; Members of this family are found in putative phage tail tape measure proteins.
Pssm-ID: 462962 [Multi-domain] Cd Length: 201 Bit Score: 120.48 E-value: 2.25e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 456 NNAASQFGQTLG----SVLDVYAEFARQGVKGNELSQFSNAALIAANVGE-IDAKQASEYLTSMSAQWETTGNQAMRQVD 530
Cdd:pfam10145 1 RDAALELGETTGfsatDAAEAMAALASAGLSAEELLSATEGALKLAVAGGaTDAAEAAEALAAAMNAFGLSADDAEEAAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 531 SLNEVSNKYATTVEKLAQGQAKAGSTAKSMGLTFDETNGIIGALTAKTkQSGDEIGNFMKATLPKLY--SGKGKSTIEGL 608
Cdd:pfam10145 81 VLAAAANNGATEVGDLADALKEVGPVAKAAGLSGEETAAALALLAAAG-ISGSEAGTALKNFLTRLAapTKEAAKALKKL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2071643352 609 GISMKDENGQLKSAISLLEEVSQKTKNLEKDQKAAVINGLGG 650
Cdd:pfam10145 160 GISAKDANGKMKSLSEILEELAQALKGLTDAQRAAALSALFG 201
|
|
| NlpD |
COG0739 |
Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell ... |
1899-2028 |
5.22e-26 |
|
Murein DD-endopeptidase MepM and murein hydrolase activator NlpD, contains LysM domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440502 [Multi-domain] Cd Length: 196 Bit Score: 107.75 E-value: 5.22e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1899 DRQFGRYNGGGVHHGRDITSATinGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKNTYT-YMHMKNPArVVKGQRVKAGQ 1976
Cdd:COG0739 85 YRRHPVTGRRRFHKGIDIAAPT--GTPVYAAADGTVVFAGWNGGyGNLVIIDHGNGYTTlYAHLSSIL-VKVGQRVKAGQ 161
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 2071643352 1977 IVGNVGTThdrrlgGFSTGPHLHVQVNLgktpsgtfmntfNGahRAVDPVKY 2028
Cdd:COG0739 162 VIGYVGNT------GRSTGPHLHFEVRV------------NG--KPVDPLPF 193
|
|
| M23_peptidase |
cd12797 |
M23 family metallopeptidase, also known as beta-lytic metallopeptidase, and similar proteins; ... |
1911-2002 |
2.51e-25 |
|
M23 family metallopeptidase, also known as beta-lytic metallopeptidase, and similar proteins; This model describes the metallopeptidase M23 family, which includes beta-lytic metallopeptidase and lysostaphin. Members of this family are zinc endopeptidases that lyse bacterial cell wall peptidoglycans; they cleave either the N-acylmuramoyl-Ala bond between the cell wall peptidoglycan and the cross-linking peptide (e.g. beta-lytic endopeptidase) or a bond within the cross-linking peptide (e.g. stapholysin, and lysostaphin). Beta-lytic metallopeptidase, formerly known as beta-lytic protease, has a preference for cleavage of Gly-X bonds and favors hydrophobic or apolar residues on either side. It inhibits growth of sensitive organisms and may potentially serve as an antimicrobial agent. Lysostaphin, produced by Staphylococcus genus, cleaves pentaglycine cross-bridges of cell wall peptidoglycan, acting as autolysins to maintain cell wall metabolism or as toxins and weapons against competing strains. Staphylolysin (also known as LasA) is implicated in a range of processes related to Pseudomonas virulence, including stimulating shedding of the ectodomain of cell surface heparan sulphate proteoglycan syndecan-1, and elastin degradation in connective tissue. Its active site is less constricted and contains a five-coordinate zinc ion with trigonal bipyramidal geometry and two metal-bound water molecules, possibly contributing to its activity against a wider range of substrates than those used by related lytic enzymes, consistent with its multiple roles in Pseudomonas virulence. The family includes members that do not appear to have the conserved zinc-binding site and might be lipoproteins lacking proteolytic activity.
Pssm-ID: 410984 [Multi-domain] Cd Length: 85 Bit Score: 101.51 E-value: 2.51e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1911 HHGRDItsATINGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKNTYT-YMHMKNPArVVKGQRVKAGQIVGNVGTThdrr 1988
Cdd:cd12797 1 HNGIDI--AAPEGTPVYAAADGTVVFAGWDGGyGNYVIIDHGNGYYTlYAHLSSIL-VKVGQRVKKGQVIGTVGNT---- 73
|
90
....*....|....
gi 2071643352 1989 lgGFSTGPHLHVQV 2002
Cdd:cd12797 74 --GRSTGPHLHFEI 85
|
|
| COG5283 |
COG5283 |
Phage-related tail protein [Mobilome: prophages, transposons]; |
323-777 |
6.21e-24 |
|
Phage-related tail protein [Mobilome: prophages, transposons];
Pssm-ID: 444094 [Multi-domain] Cd Length: 747 Bit Score: 110.33 E-value: 6.21e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 323 ALTSQIERIENRMAATID-----KQQTNALKNQLNSLGNNRTPFG---KEAAFHMNQIQDKVRQISAEAERATR------ 388
Cdd:COG5283 25 ALAQALKALEAPTRALARaleraKQAAARLQTKYNKLRQSLQRLRqalDQAGIDTRQLSAAQRRLRSSLEQTNRqlerqq 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 389 TQLSFVDQFREAMTKFPVWM--GATTLFFGAINGAKEMLDVITEID--GKMITLAKVTGDDN---ALQQTFIDANNAASQ 461
Cdd:COG5283 105 QRLARLGARQDRLKAARARLqrLAGAGAAAAAIGAALAASVKPAIDfeDAMADVAATVDLDKsseQFKALGKQARELSAQ 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 462 FGQTLGSVLDVYAEFARQGVKGNELSQFSNAALIAANVGEIDAKQASEYLTSMSAQWETTGNQAMRQVDSLNEVSNKYAT 541
Cdd:COG5283 185 TPQSADDIAAGQAALAQAGVSAEDILAFTPTAAKLATAFDTDAEEAAEIAAKILNAFKLPADDVERLGDALNYAGNNGAT 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 542 TVEKLAQGQAKAGSTAKSMGLTFDETNGIIGALtAKTKQSGDEIGNFMKATLPKLYSGKGKST--IEGLGISMKDENGQL 619
Cdd:COG5283 265 SLADLADALPYVGPVAKALGVSGKEAAALGAAL-ADAGIEGEEAGTALRNMLTRLTSPTKAAAkaLKKLGIDTQDSKGNL 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 620 KSAISLLE------------EVSQKTKNLEKDQKAAVINGLGGTyhyQRMQVLLDDLSKTDGLYKQIKESSESSAGSALQ 687
Cdd:COG5283 344 RGLAKILAkqmqkdaqgalaELLKALKKLDAAKRAAALKQLFGE---EAVSALAPLLQNGDELRKQLAVAEAAAAQGSMD 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 688 -ENAKYMESIEAKVNQAKTAFEQFALAVGETFAKS---------GMLDGIRMVTQLLTGLTHGITELGTTAPIFGMVGGA 757
Cdd:COG5283 421 kEAAKRTDTLAGQLKLLKNALENLGISIGEALLPAlrelaqaltPVVGKLADWAKANPGLIKTIVKVAAALAGLKAALGA 500
|
490 500
....*....|....*....|
gi 2071643352 758 ASLMSKNVRSGFEGARSSVA 777
Cdd:COG5283 501 LRLALALLLSPLAALKAAAA 520
|
|
| Peptidase_M23 |
pfam01551 |
Peptidase family M23; Members of this family are zinc metallopeptidases with a range of ... |
1909-2008 |
5.38e-23 |
|
Peptidase family M23; Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins such as Swiss:P33648 for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.
Pssm-ID: 460250 [Multi-domain] Cd Length: 96 Bit Score: 95.31 E-value: 5.38e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1909 GVHHGRDItsATINGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKNTYT-YMHMKNpARVVKGQRVKAGQIVGNVGTThd 1986
Cdd:pfam01551 1 RFHKGIDI--AAPTGTPVYAAADGVVVFAGWLGGyGNLVIIDHGNGYSTlYAHLSS-ILVKVGQRVKAGQVIGTVGST-- 75
|
90 100
....*....|....*....|..
gi 2071643352 1987 rrlgGFSTGPHLHVQVNLGKTP 2008
Cdd:pfam01551 76 ----GRSTGPHLHFEIRKNGKP 93
|
|
| YqbO |
COG5280 |
Phage-related minor tail protein [Mobilome: prophages, transposons]; |
433-1289 |
1.49e-21 |
|
Phage-related minor tail protein [Mobilome: prophages, transposons];
Pssm-ID: 444091 [Multi-domain] Cd Length: 962 Bit Score: 103.08 E-value: 1.49e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 433 GKMITLAKVTGDD-NALQQTFIDANNAasqFGQTLGSVLDVYAEFARQGVKGNELSQFSNAALIAANVGEIDAKQASEYL 511
Cdd:COG5280 78 STVQAVTGATGEElEALEQLAKELGAT---TGESAAEVAEALGSVAQAGLSGDELIAVTEGALVLAAATGVDLNEAAEIV 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 512 TSMSAQWETTGNQAMRQVDSLNEVSNKYATTVEKLAQGQAKAGSTAKSMGLTFDETNGIIGALTAKTKQsGDEIGNFMKA 591
Cdd:COG5280 155 ASAMNAFGLSADEASRVADLLAAGAQAGNTTSDELADALKEYAPLAAALGFSLEETLAALALLANAGIK-GSDAGTALKE 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 592 TLPKLYSGKGKS--TIEGLGISMKDENGQLKSAISLLEEVSQKTKNLEKDQKAAVINGLGGTyhyQRMQVLLDDLSKTDG 669
Cdd:COG5280 234 FLIRLADPSKTAaeALEELGINVFDASGKLKGLSEILGELAKKFAGLGEAARAAVLAAIFGD---DAGRAAIALLLFGTD 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 670 LYKQIKESSESSAGSALQENAKYMESIEAKVNQAKTAFEQFALAVGETF------AKSGMLDGIRMVTQLLTGLTHGITE 743
Cdd:COG5280 311 WYAKLTAALKNSAGAADEAAATMQDNLAGALESLKSALEGLAITIGETLlpalrdAVEALTGLADWFNELSPAVQELIIA 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 744 LGTTAPIFG---MVGGAASLMSKNVRSGFEGARSSVANYITEVnkLAK-VNNAAGQVVGLqkvqtGTASQLQFNKNGEYD 819
Cdd:COG5280 391 IAGLVAALGpllLILGALITGIGALAGAFGILSTALAKAKGAL--LAGpIGIVIAAIAAL-----AAALVLLYKNWDTIK 463
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 820 KAASQakaaeqaTYQFSKAQKDVSASAMiasgainkttvattastvaTRAATLAVNGLKLAFRGLLAATGVGLAITGVSF 899
Cdd:COG5280 464 EFLTG-------LWNSIKEAIGGVWDGI-------------------KTSVEGLKGAAGAALSAAAGKAIEALAGISVDA 517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 900 VLEKVVGSFNAASQAAEQYKQKQEQTKQAIASMSNGEINSLISSYDKLQQKMNSGSAFNTAEAEKYKEVTSQLANIFPDL 979
Cdd:COG5280 518 LKQGVILSGTISMLWGAAGTEVSLKGGAAQDNVSDAASSAGDGALAIINSAEQAIIGLAAALKTASTSSALQASTKAAAA 597
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 980 VTGENRYG-KEMAGNKEVMKQKIELIKQemeLERQKNAIKQKEEQDAYIKEQDSLAKKNRGQKWYQLGQTPELKLQEQAR 1058
Cdd:COG5280 598 TKAEKTILaIAMATVKGVTSATAALANA---AGVILQGAIKNGISGALDSAGATTVAKLAEEEAINEKIVELLKAAANGA 674
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1059 PTTVSDNSNiNKINATIQKVKSQAQAEKALEQVDKQLAQSQTKNRQNevqhLQKVRQALQDYITKTGQANQATRAAVLTA 1138
Cdd:COG5280 675 NKEAVANAL-LLDAAAKQNINGQEAILEGITAKGVQTDELQDSDAIQ----AKFQFEELSEGAKATINAINGNGVLGGII 749
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1139 QQQFTNQIATMKKLGTtgqqVMTTISNSVAKtaksgKAAQATFKSFETSLVKSSSFKSKMASYEasVKKFKNAANQSAKI 1218
Cdd:COG5280 750 ADGIKTNSAELKAAAN----ELKGDINRVAA-----AINSLAEAGAEEIKSEAKEAGSDKAITG--EAGQAALELAVARV 818
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2071643352 1219 AALKDVERDYSKVAKGIMQAAKAANMSKSQMKDLKKSLQQNIQAETGFRA--SVSKAGKVTIDQSKKIKQNTA 1289
Cdd:COG5280 819 NALISRVTKNITGTLSGSTVSILKGNTTEIENASKKITESGDKIMTGKDIelLAEGEFAVLIKNVKANGGNIA 891
|
|
| SpoIIQ2 |
COG5821 |
Stage II sporulation protein SpoIIQ, clostridial version, metallopeptidase M23 family [Cell ... |
1910-2028 |
9.65e-12 |
|
Stage II sporulation protein SpoIIQ, clostridial version, metallopeptidase M23 family [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444523 [Multi-domain] Cd Length: 200 Bit Score: 66.59 E-value: 9.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1910 VHHGRDITSATinGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKN-TYTYMHMKNPARVVKGQRVKAGQIVGNVGTThdr 1987
Cdd:COG5821 96 THTGIDIAAKE--GTPVKAAADGVVVEVGKDPKyGITVVIDHGNGiKTVYANLDSKIKVKVGQKVKKGQVIGKVGST--- 170
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2071643352 1988 rlGGF--STGPHLHVQVNLGKTPsgtfmntfngahraVDPVKY 2028
Cdd:COG5821 171 --ALFesSEGPHLHFEVLKNGKP--------------VDPMKY 197
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1900-2002 |
5.35e-11 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 67.10 E-value: 5.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1900 RQFGRYNGGGVHH-GRDItsATINGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKNTYT-YMHMKNPArVVKGQRVKAGQ 1976
Cdd:COG4942 265 RRFGERDGGGGRNkGIDI--AAPPGAPVRAVADGTVVYAGWLRGyGNLVIIDHGGGYLTlYAHLSSLL-VKVGQRVKAGQ 341
|
90 100
....*....|....*....|....*.
gi 2071643352 1977 IVGNVGTThdrrlgGFSTGPHLHVQV 2002
Cdd:COG4942 342 PIGTVGSS------GGQGGPTLYFEL 361
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2060-2588 |
1.72e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.01 E-value: 1.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2060 AEDLNEAEQERlnKIEQAinahNKAEEMKqKVDELRKTLMDKQLEEVQTAKEKSENLYNIQKSH-VEEYDHWRTLQEARS 2138
Cdd:PTZ00121 1190 AEELRKAEDAR--KAEAA----RKAEEER-KAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEeERNNEEIRKFEEARM 1262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2139 AKLEYELNKIEFEKGRNTKEWRnKNKQLQASRQLEVNFEDSKIQYINKAL--KKNANKIFGKNTVNRDEFETMKRDAQQn 2216
Cdd:PTZ00121 1263 AHFARRQAAIKAEEARKADELK-KAEEKKKADEAKKAEEKKKADEAKKKAeeAKKADEAKKKAEEAKKKADAAKKKAEE- 1340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2217 irdlkagiQTASGEIATSMIDQILDEYEDRVGKVSAKIEKMGKQKEKLDladnkqALKSSSLSRQQAKDSKSLASYINFY 2296
Cdd:PTZ00121 1341 --------AKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD------AAKKKAEEKKKADEAKKKAEEDKKK 1406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2297 IKQLERQLKLTGKNHELQQKVKEQIKemkvayddatlaAHQYITEAAEVDTERQLQLNANRLRDAQNELSKADYKAGFIS 2376
Cdd:PTZ00121 1407 ADELKKAAAAKKKADEAKKKAEEKKK------------ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2377 QEYQIDLYRKNQEAKFKGYLKEKEALEQNKSELQDMYEIYKSVPTQAQKIKEAL-IETKNAIRDNNKGLYDLKYDMANSV 2455
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKkAEEAKKADEAKKAEEKKKADELKKA 1554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2456 INQIKDIYSKQLEVATKAYDDEYKAYEKMinKKLKLIDDEQTQESFNKDVRDRTEAMDKIRDEIAQRSGDDSLANQKKLK 2535
Cdd:PTZ00121 1555 EELKKAEEKKKAEEAKKAEEDKNMALRKA--EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 2071643352 2536 DLREQLKQQEEDYTMFINN-KNRDDRRKALQDELNDKNEQIQEQKEDLNKAFQD 2588
Cdd:PTZ00121 1633 KKVEQLKKKEAEEKKKAEElKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED 1686
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2056-2741 |
3.43e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.85 E-value: 3.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2056 SAAMAEDLNEAEQERLNKIEQAINAHNKAEEMKQKVDELRKTLMDKQLEEVQTAKEKSENLYNIQKSHV--EEYDHWRTL 2133
Cdd:PTZ00121 1204 AARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIkaEEARKADEL 1283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2134 QEARSAKLEYELNKIefEKGRNTKEWRNKNKQLQASRQLEVNFEDSKIQyiNKALKKNANKIFGKNTVNRDEFETMKRDA 2213
Cdd:PTZ00121 1284 KKAEEKKKADEAKKA--EEKKKADEAKKKAEEAKKADEAKKKAEEAKKK--ADAAKKKAEEAKKAAEAAKAEAEAAADEA 1359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2214 QQNIRDLKAgiqtasGEIATSMIDQILDEYEDRVGKVSAKIEKMGKQKEKLDLADNkqaLKSSSLSRQQAKDSKSLASYI 2293
Cdd:PTZ00121 1360 EAAEEKAEA------AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADE---LKKAAAAKKKADEAKKKAEEK 1430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2294 NfYIKQLERQLKLTGKNHELQQKVKEQIK--EMKVAYDDATLA--AHQYITEAAEVDTER----QLQLNANRLRDAQNEL 2365
Cdd:PTZ00121 1431 K-KADEAKKKAEEAKKADEAKKKAEEAKKaeEAKKKAEEAKKAdeAKKKAEEAKKADEAKkkaeEAKKKADEAKKAAEAK 1509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2366 SKADyKAGFISQEYQIDLYRKNQEAKFKGYLKEKEALEQnKSELQDMYEIYKSVPTQAQKIKEALIETKNAIRDNNKGLY 2445
Cdd:PTZ00121 1510 KKAD-EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKK-ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK 1587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2446 DLKYDMANSVINQIKDIYSKQLEVATKAYDDEYKAYE----KMINKKLKLIDDEQTQESFNKDVRDRTEAMDKIRDEIAQ 2521
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElkkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEA 1667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2522 RSGDDSLANQKKLKDLREQLKQQEEDYTMFINNKNRDDRRKALQDELNDKNEQIQEQKEDLNKAFQDLIGDTRRFNAIQE 2601
Cdd:PTZ00121 1668 KKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAE 1747
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2602 SLMEGQIDKYKslIADLTKYVNDNMKEIGRSTSEGILDGLAASFKGLSSLSKELQKQEKNNLNPVPNSKLKPTKV----D 2677
Cdd:PTZ00121 1748 EAKKDEEEKKK--IAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVindsK 1825
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2071643352 2678 EATIAAIKKVNGLSPTTILQGLDIKPVNLPKDVKPSKTvTNNNKTTAKALVNIENFNGTKAEAD 2741
Cdd:PTZ00121 1826 EMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGED-GNKEADFNKEKDLKEDDEEEIEEAD 1888
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2070-2589 |
3.49e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 59.31 E-value: 3.49e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2070 RLNKIEQAI-NAHNKAEEMKQKVDELRKTLM-----DKQLEEVQtaKEKSENLYNIQKSHVEEYDHWRTLQEARSAKLEY 2143
Cdd:PRK03918 156 GLDDYENAYkNLGEVIKEIKRRIERLEKFIKrteniEELIKEKE--KELEEVLREINEISSELPELREELEKLEKEVKEL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2144 ELNKIEFEKGRNTKEWRNKN-KQLQAS-RQLEVNFEDSKIQYinKALKKNA---NKIFGKNTVNRdEFETMKRDAQQNIR 2218
Cdd:PRK03918 234 EELKEEIEELEKELESLEGSkRKLEEKiRELEERIEELKKEI--EELEEKVkelKELKEKAEEYI-KLSEFYEEYLDELR 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2219 DLKAGIQTASGEIAtsmidqildEYEDRVGKVSAKIEKMGKQKEKL-DLADNKQALKSSSLSRQQAKDSKslasyinfyi 2297
Cdd:PRK03918 311 EIEKRLSRLEEEIN---------GIEERIKELEEKEERLEELKKKLkELEKRLEELEERHELYEEAKAKK---------- 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2298 KQLER-QLKLTGKNHElqqKVKEQIKEMKVAYDDATLAAHQYITEAAEVDTERqlqlnaNRLRDAQNELSKADYKAGF-- 2374
Cdd:PRK03918 372 EELERlKKRLTGLTPE---KLEKELEELEKAKEEIEEEISKITARIGELKKEI------KELKKAIEELKKAKGKCPVcg 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2375 --ISQEYQIDLYRKnqeakfkgYLKEKEALEQNKSELQDmyeiyksvptQAQKIKEALIETKNAIRDNNKgLYDLKydma 2452
Cdd:PRK03918 443 reLTEEHRKELLEE--------YTAELKRIEKELKEIEE----------KERKLRKELRELEKVLKKESE-LIKLK---- 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2453 nSVINQIKDIYSKQLEVATKAYDDEYKAYEKMINKKLKL-------IDDEQTQESFNKDVRDRTEAMDKIRDEIAQRSGD 2525
Cdd:PRK03918 500 -ELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLkgeikslKKELEKLEELKKKLAELEKKLDELEEELAELLKE 578
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2071643352 2526 DSLANQKKLKDLREQLKQQEEDYTMFINNKNRDDRRKALQDELNDKNEQIQEQKEDLNKAFQDL 2589
Cdd:PRK03918 579 LEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRL 642
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
2236-2660 |
2.60e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 56.67 E-value: 2.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2236 IDQILDEYEDRVGKVSAKIEKMGKQKEK---------LDLADNKQALKS-----SSLSRQQAKDSKSLASYINFYIKQLE 2301
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELHEKqkfylrqsvIDLQTKLQEMQMerdamADIRRRESQSQEDLRNQLQNTVHELE 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2302 --RQLK---LTGKNHELQQKVKEQI------KEMKVAYDDATLAAHQYITEAAEVDTE--RQLQLNANR-LRDAQNELSK 2367
Cdd:pfam15921 156 aaKCLKedmLEDSNTQIEQLRKMMLshegvlQEIRSILVDFEEASGKKIYEHDSMSTMhfRSLGSAISKiLRELDTEISY 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2368 adYKAGFISQEYQIDLYRKNQEAKFKGYLKE-----KEALEQNKSELQDMYEIYKSVPTQAQKIKEALIETKNAIRDNNk 2442
Cdd:pfam15921 236 --LKGRIFPVEDQLEALKSESQNKIELLLQQhqdriEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN- 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2443 GLYDLKYDMANSVINQIKdiysKQLEVATKAYDDEYKAYEKminkKLKLIDDEQTQEsfnkdvrdRTEamdkiRDEIAQR 2522
Cdd:pfam15921 313 SMYMRQLSDLESTVSQLR----SELREAKRMYEDKIEELEK----QLVLANSELTEA--------RTE-----RDQFSQE 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2523 SG--DDSLanQKKLKDLREQLK----QQEEDYTMFINNKNRDDRRKALQDELNDKNEQIQEQKEDLNKAFQDLIGDT-RR 2595
Cdd:pfam15921 372 SGnlDDQL--QKLLADLHKREKelslEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMeRQ 449
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2071643352 2596 FNAIQ---ESLmegqiDKYKSLIADLtkyvnDNMKEIGRSTSEGILDG---LAASFKGLSSLSKELQKQEK 2660
Cdd:pfam15921 450 MAAIQgknESL-----EKVSSLTAQL-----ESTKEMLRKVVEELTAKkmtLESSERTVSDLTASLQEKER 510
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2065-2585 |
1.69e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.99 E-value: 1.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2065 EAEQERLNKIEQAinahNKAEEMKQKVDELRKTLMDKQLEEVQTAKEKSENLYNIQKSHVEEYDHWRTLQEARSAKleyE 2144
Cdd:PTZ00121 1102 EAKKTETGKAEEA----RKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE---D 1174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2145 LNKIE----FEKGRNTKEWRNKN--KQLQASRQLEvnfEDSKIQYINKAL-KKNANKIFGKNTVNRDEFETMKRDAQQNI 2217
Cdd:PTZ00121 1175 AKKAEaarkAEEVRKAEELRKAEdaRKAEAARKAE---EERKAEEARKAEdAKKAEAVKKAEEAKKDAEEAKKAEEERNN 1251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2218 RDLKAGIQTASGEIATSMIDQILDEY----------------EDRVGKVSAKIEKMGKQKEKLDLADN-----KQALKSS 2276
Cdd:PTZ00121 1252 EEIRKFEEARMAHFARRQAAIKAEEArkadelkkaeekkkadEAKKAEEKKKADEAKKKAEEAKKADEakkkaEEAKKKA 1331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2277 SLSRQQAKDSKSLASYINFYIKQLERQLKLTGKNHELQQKVKEQIK----------EMKVAYDDATLAAHQYITEAAEVD 2346
Cdd:PTZ00121 1332 DAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKkkadaakkkaEEKKKADEAKKKAEEDKKKADELK 1411
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2347 TERQLQLNANRLRDAQNELSKADYKAGFISQEYQIDLYRKNQEAKFKGYLKEKEALEQNKS-ELQDMYEIYKSVPTQAQK 2425
Cdd:PTZ00121 1412 KAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAdEAKKKAEEAKKADEAKKK 1491
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2426 IKEAlieTKNAIRDNNKGLYDLKYDMANSVINQIKDIYSKQLEVATKAyDDEYKAYEKMINKKLKLIDDEQTQESFNKDV 2505
Cdd:PTZ00121 1492 AEEA---KKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA-DEAKKAEEKKKADELKKAEELKKAEEKKKAE 1567
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2506 RDRTEAMDKI----RDEIAQRSGDDSLANQKKLKDLR-----EQLKQQEEDYTMFINNKNRDDRRKALQdELNDKNEQIQ 2576
Cdd:PTZ00121 1568 EAKKAEEDKNmalrKAEEAKKAEEARIEEVMKLYEEEkkmkaEEAKKAEEAKIKAEELKKAEEEKKKVE-QLKKKEAEEK 1646
|
....*....
gi 2071643352 2577 EQKEDLNKA 2585
Cdd:PTZ00121 1647 KKAEELKKA 1655
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
901-1273 |
2.86e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.14 E-value: 2.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 901 LEKVVGSFNAASQAAEQYKQKQEQTKQAIASMSNGEINSLISSYDKLQQKMNsgsafntAEAEKYKEVTSQLANIFPDLV 980
Cdd:TIGR02168 198 LERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELK-------EAEEELEELTAELQELEEKLE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 981 TGENRygkemagnKEVMKQKIELIKQemELERQKNAIKQKEEQDAYIKEQDSLAKKNRGQKWYQLGQTPELKLQEQARPT 1060
Cdd:TIGR02168 271 ELRLE--------VSELEEEIEELQK--ELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1061 TVSDnsNINKINATIQKVKSQAQAEKALEQVDKQLAQSQTKNRQNEVQHLQKVRQALQDyITKTGQANQATRAAVLTAQQ 1140
Cdd:TIGR02168 341 ELEE--KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS-LNNEIERLEARLERLEDRRE 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1141 QFTNQIATMKKLGTTGQqvMTTISNSVAKTAKSGKAAQATFKSFETSLvksSSFKSKMASYEASVKKFKNAANQ-SAKIA 1219
Cdd:TIGR02168 418 RLQQEIEELLKKLEEAE--LKELQAELEELEEELEELQEELERLEEAL---EELREELEEAEQALDAAERELAQlQARLD 492
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2071643352 1220 ALKDVERDYSKVAKGImqaaKAANMSKSQMKDLKKSLQQNIQAETGFRASVSKA 1273
Cdd:TIGR02168 493 SLERLQENLEGFSEGV----KALLKNQSGLSGILGVLSELISVDEGYEAAIEAA 542
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2240-2621 |
3.90e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.76 E-value: 3.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2240 LDEYEDRVGKVSAKIEKMGKQKEKL-----------DLADNKQALKSSSLSRQQAKDSKSLA------SYINFYIKQLER 2302
Cdd:TIGR02169 179 LEEVEENIERLDLIIDEKRQQLERLrrerekaeryqALLKEKREYEGYELLKEKEALERQKEaierqlASLEEELEKLTE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2303 QLKLTGKN-HELQQKVKEQIKEMKVAYDDATLAAHQYI--TEAAEVDTERQLQLNANRLRDAQNELSKADYKAGfiSQEY 2379
Cdd:TIGR02169 259 EISELEKRlEEIEQLLEELNKKIKDLGEEEQLRVKEKIgeLEAEIASLERSIAEKERELEDAEERLAKLEAEID--KLLA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2380 QIDLYRKNQEAkfkgYLKEKEALEQNKSELQDMYEIYKSvptQAQKIKEALIETKNAIRDnnkglYDLKYDMANSVINQI 2459
Cdd:TIGR02169 337 EIEELEREIEE----ERKRRDKLTEEYAELKEELEDLRA---ELEEVDKEFAETRDELKD-----YREKLEKLKREINEL 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2460 KDIYSKQLEVATKAYDDEYKayekmINKKLKLIDDEQTQesFNKDVRDRTEAMDKIRDEIAQrsgddslaNQKKLKDLRE 2539
Cdd:TIGR02169 405 KRELDRLQEELQRLSEELAD-----LNAAIAGIEAKINE--LEEEKEDKALEIKKQEWKLEQ--------LAADLSKYEQ 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2540 QLKQQEEDYtmfinnknrddrrKALQDELNDKNEQIQEQkedlnKAFQDLIGDTRRFNAIQESLMEGQIDKYKSLIADLT 2619
Cdd:TIGR02169 470 ELYDLKEEY-------------DRVEKELSKLQRELAEA-----EAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531
|
..
gi 2071643352 2620 KY 2621
Cdd:TIGR02169 532 SV 533
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2042-2445 |
4.10e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.76 E-value: 4.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2042 GSLTSGHSAMSGSISAA---------MAEDLNEAE------QERLNKIEQAIN-AHNKAEEMKQKVDELRKTLmDKQLEE 2105
Cdd:TIGR02169 653 GAMTGGSRAPRGGILFSrsepaelqrLRERLEGLKrelsslQSELRRIENRLDeLSQELSDASRKIGEIEKEI-EQLEQE 731
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2106 VQTAKEKSENLYNIQKShveeydhwrtLQEARSAKlEYELNKIEFEKGRNTKEWRNKNKQLQAsrqLEVNFEDSKIQYIN 2185
Cdd:TIGR02169 732 EEKLKERLEELEEDLSS----------LEQEIENV-KSELKELEARIEELEEDLHKLEEALND---LEARLSHSRIPEIQ 797
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2186 KALKKnANKIfgkntvnRDEFETMKRDAQQNIRDLKAGIQTASGEIATsmIDQILDEYEDRVGKVSAKIEKMGKQKEKLD 2265
Cdd:TIGR02169 798 AELSK-LEEE-------VSRIEARLREIEQKLNRLTLEKEYLEKEIQE--LQEQRIDLKEQIKSIEKEIENLNGKKEELE 867
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2266 --LADNKQALK--SSSLSRQQAKDSKSLASYINFYIKQLERQLKLTGKNHEL-QQKVKEQIKEMKVAYDDATLAAHQYIT 2340
Cdd:TIGR02169 868 eeLEELEAALRdlESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLsELKAKLEALEEELSEIEDPKGEDEEIP 947
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2341 EaaEVDTERQLQLNANRLRDAQNELSKADYKAgfiSQEYQIDLYRKNQeakfkgyLKEKEA-LEQNKSELQDMYEIYKsv 2419
Cdd:TIGR02169 948 E--EELSLEDVQAELQRVEEEIRALEPVNMLA---IQEYEEVLKRLDE-------LKEKRAkLEEERKAILERIEEYE-- 1013
|
410 420
....*....|....*....|....*.
gi 2071643352 2420 ptqaQKIKEALIETKNAIRDNNKGLY 2445
Cdd:TIGR02169 1014 ----KKKREVFMEAFEAINENFNEIF 1035
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2065-2660 |
1.37e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.83 E-value: 1.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2065 EAEQERLNKIEQAINahnkaeEMKQKVDELRKtlmdkQLEEVQTAKEKSENLYNIQKSHVeeYDHWRTLQEARSAkLEYE 2144
Cdd:TIGR02168 182 ERTRENLDRLEDILN------ELERQLKSLER-----QAEKAERYKELKAELRELELALL--VLRLEELREELEE-LQEE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2145 LNKIEFEKGRNTKEWRNKNKQLQASRqLEVNFEDSKIQYINKALKKNANKIfgkntvnrDEFETMKRDAQQNIRDLKAGI 2224
Cdd:TIGR02168 248 LKEAEEELEELTAELQELEEKLEELR-LEVSELEEEIEELQKELYALANEI--------SRLEQQKQILRERLANLERQL 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2225 QTASGEIATSmiDQILDEYEDRVGKVSAKI-EKMGKQKEKLDLADNKQALKSSSLSRQQAKD-------------SKSLA 2290
Cdd:TIGR02168 319 EELEAQLEEL--ESKLDELAEELAELEEKLeELKEELESLEAELEELEAELEELESRLEELEeqletlrskvaqlELQIA 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2291 SyINFYIKQLERQLKLTGKNHE-LQQKVKEQIKEM------KVAYDDATLAAHQYITEAAEVDTERQLQLNANRLRDAQN 2363
Cdd:TIGR02168 397 S-LNNEIERLEARLERLEDRRErLQQEIEELLKKLeeaelkELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2364 ELSKADYKAGFISQEYQIdlyRKNQEAKFKGYLKEKEALEQNKSELQDMY----EIYKSVPTQAQKIKEAL--------I 2431
Cdd:TIGR02168 476 ALDAAERELAQLQARLDS---LERLQENLEGFSEGVKALLKNQSGLSGILgvlsELISVDEGYEAAIEAALggrlqavvV 552
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2432 ETKNAIRD-------NNKG------LYDLKYDMANSVINQIKDIYSKQLEVAtKAYDDEYKAYEKMINKKL---KLIDDE 2495
Cdd:TIGR02168 553 ENLNAAKKaiaflkqNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVA-KDLVKFDPKLRKALSYLLggvLVVDDL 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2496 QT----QESFNKDVRDRTEAMDKIRDEIAQRSGDDS-----LANQKKLKDLREQLKQQEEDYTmfinnknrddrrkALQD 2566
Cdd:TIGR02168 632 DNalelAKKLRPGYRIVTLDGDLVRPGGVITGGSAKtnssiLERRREIEELEEKIEELEEKIA-------------ELEK 698
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2567 ELNDKNEQIQEQKEDLNKAFQDLIGDTRRFNAIQESL--MEGQIDKYKSLIADLTKYVNDNMKEIgrstsEGILDGLAAS 2644
Cdd:TIGR02168 699 ALAELRKELEELEEELEQLRKELEELSRQISALRKDLarLEAEVEQLEERIAQLSKELTELEAEI-----EELEERLEEA 773
|
650
....*....|....*.
gi 2071643352 2645 FKGLSSLSKELQKQEK 2660
Cdd:TIGR02168 774 EEELAEAEAEIEELEA 789
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2065-2580 |
1.50e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.91 E-value: 1.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2065 EAEQERLNKIEQAINAHNKAEEMKQKVDELRKTLMDKQleEVQTAKEKSEnlyniQKSHVEEYDhwRTLQEARSAKleyE 2144
Cdd:PTZ00121 1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKK--KADEAKKKAE-----EKKKADEAK--KKAEEAKKAD---E 1448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2145 LNKiEFEKGRNTKEWRNKNKQLQASRQLEVNFEDSKIQyinKALKKNANKIFGKNTVNRDEFETMKRDAQQNIRDLKAGI 2224
Cdd:PTZ00121 1449 AKK-KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA---DEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA 1524
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2225 QTASGEIATSMIDQILDEYEDRVGKVSAKIEKMGKQKEKLDLADNKQALKSSSLSRQQAKDSKSL-ASYINFYIKQLERQ 2303
Cdd:PTZ00121 1525 DEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAeEARIEEVMKLYEEE 1604
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2304 LKLTGKNHELQQKVKEQIKEMKVAYDDATLAAHQYITEAAEVDTERQLQ--------LNANRLRDAQNELSKAD--YKAG 2373
Cdd:PTZ00121 1605 KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKkaeeenkiKAAEEAKKAEEDKKKAEeaKKAE 1684
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2374 FISQEYQIDLYRKNQEAKFKGYLKEKEALEQNKSElqdmyEIYKSVPTQAQKIKEAlieTKNAIRDNNKGLYDLKYDMAN 2453
Cdd:PTZ00121 1685 EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAE-----ELKKAEEENKIKAEEA---KKEAEEDKKKAEEAKKDEEEK 1756
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2454 SVINQIKDIYSKQLE--------VATKAYDDEYKAYEKMINKKLKLIDD--EQTQESFNKD---VRDRTEAMDKIRDEIA 2520
Cdd:PTZ00121 1757 KKIAHLKKEEEKKAEeirkekeaVIEEELDEEDEKRRMEVDKKIKDIFDnfANIIEGGKEGnlvINDSKEMEDSAIKEVA 1836
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2521 qrsgdDSLANQKKLKDLREQLKQQEEDYTMFINNKNRDDRRKalQDELNDKNEQIQEQKE 2580
Cdd:PTZ00121 1837 -----DSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKE--KDLKEDDEEEIEEADE 1889
|
|
| PRK11649 |
PRK11649 |
putative peptidase; Provisional |
1911-2002 |
2.71e-05 |
|
putative peptidase; Provisional
Pssm-ID: 236946 [Multi-domain] Cd Length: 439 Bit Score: 49.28 E-value: 2.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1911 HHGRDItsATINGSPIKAARSGIVTFKGWTGG-GNTLSIFDGKnTYT--YMHMKNpaRVVK-GQRVKAGQIVGNVGTThd 1986
Cdd:PRK11649 313 HRGVDF--AMPVGTPVLAVGDGEVVVAKRSGAaGNYVAIRHGR-QYTtrYMHLRK--LLVKpGQKVKRGDRIALSGNT-- 385
|
90
....*....|....*.
gi 2071643352 1987 rrlgGFSTGPHLHVQV 2002
Cdd:PRK11649 386 ----GRSTGPHLHYEV 397
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
2044-2583 |
3.51e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 49.58 E-value: 3.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2044 LTSGHSAMSGSISAAMAEDlnEAEQERLNKIEQAINahNKAEEMKQKVDELRKTLmdkqleevQTAKEKSENLYNIQKSH 2123
Cdd:TIGR00618 415 RTSAFRDLQGQLAHAKKQQ--ELQQRYAELCAAAIT--CTAQCEKLEKIHLQESA--------QSLKEREQQLQTKEQIH 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2124 vEEYDHWRTLQEARsaKLEYELNKIEFEKgrntkEWRNKNKQLQASRQLEVNFED-SKIQYINKALKKNANKIFGKNTVN 2202
Cdd:TIGR00618 483 -LQETRKKAVVLAR--LLELQEEPCPLCG-----SCIHPNPARQDIDNPGPLTRRmQRGEQTYAQLETSEEDVYHQLTSE 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2203 RDEFETMKRDAQQNIRDLKAGIQ-----TASGEIATSMIDQILDEyedrvgkvsakIEKMGKQKEKLDLADNKQALKsss 2277
Cdd:TIGR00618 555 RKQRASLKEQMQEIQQSFSILTQcdnrsKEDIPNLQNITVRLQDL-----------TEKLSEAEDMLACEQHALLRK--- 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2278 LSRQQAKDSKSLasyinfyikqlerqlkltgknhELQQKVKEQIKEMKVAYDDATLAAHQYITEAAEVDTERQLQLNANR 2357
Cdd:TIGR00618 621 LQPEQDLQDVRL----------------------HLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASR 678
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2358 LRDAQNELSKADYKAGFisqeyqidlyrknqeakfkgylkeKEALEQNKSELQDMYEIYKSVPTQAQKIKEALIETKNAI 2437
Cdd:TIGR00618 679 QLALQKMQSEKEQLTYW------------------------KEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDL 734
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2438 RDNNkglydlkyDMANSVINQIKDIYSKQLEVATKAYDDEYKAYEKMINKKLKLIDDEQTQESFNKDVRDRTEAMDKIRD 2517
Cdd:TIGR00618 735 AARE--------DALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2071643352 2518 EIAQRSGDDS---LANQKKLKDLREQLKQQ-EEDYTMFINNKN---RDDRRKALQDELNDKNEQIQEQKEDLN 2583
Cdd:TIGR00618 807 EIGQEIPSDEdilNLQCETLVQEEEQFLSRlEEKSATLGEITHqllKYEECSKQLAQLTQEQAKIIQLSDKLN 879
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
2057-2578 |
4.66e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 48.95 E-value: 4.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2057 AAMAEDLNEAEQERLNKIEQAINAHNKAEEMKQKVDELRKTLMDKQLEEVQTAKEKSENLYNIQKSHVEEYDHWR---TL 2133
Cdd:pfam05483 165 ARSAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEkqvSL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2134 QEARSAKLEYELNKIEF--EKGRNTKEWRNKNKQLQASRQLEVN---------FEDSKIQY-----INKALKKN---ANK 2194
Cdd:pfam05483 245 LLIQITEKENKMKDLTFllEESRDKANQLEEKTKLQDENLKELIekkdhltkeLEDIKMSLqrsmsTQKALEEDlqiATK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2195 IFGKNTVNR----DEFETMKRDAQQNIRDLKAGIQTASGEIATSmiDQILDEYEDRVGKVSAKIEKMGKQKEKLDLADNK 2270
Cdd:pfam05483 325 TICQLTEEKeaqmEELNKAKAAHSFVVTEFEATTCSLEELLRTE--QQRLEKNEDQLKIITMELQKKSSELEEMTKFKNN 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2271 QALKSSSLSRQQAKDSKSLasYINFYIKQLERQLKltGKNHELQ---QKVKEQIKEMKVAYDDATLAAHQYITEAAEVDT 2347
Cdd:pfam05483 403 KEVELEELKKILAEDEKLL--DEKKQFEKIAEELK--GKEQELIfllQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKT 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2348 E--------RQLQLNANRLRDAQNELSKADYKAGFISQEYQIDLYR-KNQEAKFkgyLKEKEALEQNKSELQDMYE-IYK 2417
Cdd:pfam05483 479 ElekeklknIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINcKKQEERM---LKQIENLEEKEMNLRDELEsVRE 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2418 SVPTQAQKIKEALIETKNAIRDNNKGLYDLKYDMA------NSVINQI--KDIYSKQLEVATKAY-------DDEYKAYE 2482
Cdd:pfam05483 556 EFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKilenkcNNLKKQIenKNKNIEELHQENKALkkkgsaeNKQLNAYE 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2483 KMINK-KLKLIDDEQTQE----SFNKDVRDRTEAMDKIRDEI--AQRSGDDSLANQKKLkDLREQLKQQEEDYTMFINNK 2555
Cdd:pfam05483 636 IKVNKlELELASAKQKFEeiidNYQKEIEDKKISEEKLLEEVekAKAIADEAVKLQKEI-DKRCQHKIAEMVALMEKHKH 714
|
570 580
....*....|....*....|...
gi 2071643352 2556 NRDDRRKALQDELNDKNEQIQEQ 2578
Cdd:pfam05483 715 QYDKIIEERDSELGLYKNKEQEQ 737
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
2068-2663 |
5.48e-05 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 48.89 E-value: 5.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2068 QERLNKIEQAINAHNKAEEM--------KQKVDELRKTLMDK--QLEEVQTAKEKSENLYNIQKSHVEEYDHWRTlqeaR 2137
Cdd:TIGR00606 188 LETLRQVRQTQGQKVQEHQMelkylkqyKEKACEIRDQITSKeaQLESSREIVKSYENELDPLKNRLKEIEHNLS----K 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2138 SAKLEYELNKIEFEKgrntKEWRNKNKQLQASRQLEVNFEDSKIqyinkalkknaNKIFGKNTVNRDEFETMKRDAQQNI 2217
Cdd:TIGR00606 264 IMKLDNEIKALKSRK----KQMEKDNSELELKMEKVFQGTDEQL-----------NDLYHNHQRTVREKERELVDCQREL 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2218 RDLKAGIQTASGEIAtsmidqildEYEDRVGKVSAKIEKMGKQKEKLDLADNKQALKSSSLSRQQAKDS-KSLASYINFY 2296
Cdd:TIGR00606 329 EKLNKERRLLNQEKT---------ELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSeRQIKNFHTLV 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2297 IKQLERQLKLTGKN-HELQQKVKE-------------------QIKEMKVAYDDATLAAHQYITEAAEVDTERQLQLNaN 2356
Cdd:TIGR00606 400 IERQEDEAKTAAQLcADLQSKERLkqeqadeirdekkglgrtiELKKEILEKKQEELKFVIKELQQLEGSSDRILELD-Q 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2357 RLRDAQNELSKADyKAGFISQEYQIDLYRKNQEAKFkgyLKEKEALEQNKSELQDmyeiyksvPTQAQKIKEALIETKNa 2436
Cdd:TIGR00606 479 ELRKAERELSKAE-KNSLTETLKKEVKSLQNEKADL---DRKLRKLDQEMEQLNH--------HTTTRTQMEMLTKDKM- 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2437 irDNNKGLYDLKYDMANSVINQIKDI-YSKQLEVATKAYDDEYKAYEKMINK-KLKLIDDEQTQESFNKDVRDRTEAMDK 2514
Cdd:TIGR00606 546 --DKDEQIRKIKSRHSDELTSLLGYFpNKKQLEDWLHSKSKEINQTRDRLAKlNKELASLEQNKNHINNELESKEEQLSS 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2515 IRDEIAQRSGddSLANQKKLKDLREQLKQQEEDYTMFINNKNRDDRrkaLQDELNDKN-------EQIQEQKEDLNKAFQ 2587
Cdd:TIGR00606 624 YEDKLFDVCG--SQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQ---FITQLTDENqsccpvcQRVFQTEAELQEFIS 698
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2071643352 2588 DLIGDTRRFNAIQESLmEGQIDKYKSLIADLTKYVNDNMKEIGRSTSEgildgLAASFKGLSSLSKELQKqEKNNL 2663
Cdd:TIGR00606 699 DLQSKLRLAPDKLKST-ESELKKKEKRRDEMLGLAPGRQSIIDLKEKE-----IPELRNKLQKVNRDIQR-LKNDI 767
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2297-2609 |
9.13e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 9.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2297 IKQLERQLK-LTGKNHELQQKVKE---QIKEMKVAYDDATLAAHQYITEAAEVDTE-RQLQLNANRLRDAQNELSKADYK 2371
Cdd:TIGR02168 679 IEELEEKIEeLEEKIAELEKALAElrkELEELEEELEQLRKELEELSRQISALRKDlARLEAEVEQLEERIAQLSKELTE 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2372 AGFISQEYQIDLYRKNQEAKfkgylkekeALEQNKSELQDMYEIYKSvptQAQKIKEALIETKNAIRDNNKGLYDLKYDM 2451
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELA---------EAEAEIEELEAQIEQLKE---ELKALREALDELRAELTLLNEEAANLRERL 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2452 ANSViNQIKDIySKQLEVATKAYDDEykayekminkklkliddEQTQESFNKDVRDRTEAMDKIRDEIAqrsgddslANQ 2531
Cdd:TIGR02168 827 ESLE-RRIAAT-ERRLEDLEEQIEEL-----------------SEDIESLAAEIEELEELIEELESELE--------ALL 879
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2071643352 2532 KKLKDLREQLKQQEEDYTmfinnkNRDDRRKALQDELNDKNEQIQEQKEDLNKAFQDLIGDTRRFNAIQESLMEGQID 2609
Cdd:TIGR02168 880 NERASLEEALALLRSELE------ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2213-2541 |
2.03e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2213 AQQNIRDLKAGIQTASGEIAT--------SMIDQiLDEYEDRVGKVSAKIEKMGKQKEKLDLADNK-QALKssslsrQQA 2283
Cdd:COG4913 622 LEEELAEAEERLEALEAELDAlqerrealQRLAE-YSWDEIDVASAEREIAELEAELERLDASSDDlAALE------EQL 694
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2284 KDSKSLasyinfyIKQLERQL-KLTGKNHELQQKVK---EQIKEMKVAYDDATLAAHQYITEAAE--------------- 2344
Cdd:COG4913 695 EELEAE-------LEELEEELdELKGEIGRLEKELEqaeEELDELQDRLEAAEDLARLELRALLEerfaaalgdaverel 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2345 -VDTERQLQLNANRLRDAQNELSKA--DYKA--GFISQEYQIDL-----YRK-----------NQEAKFKGYLKEKEalE 2403
Cdd:COG4913 768 rENLEERIDALRARLNRAEEELERAmrAFNRewPAETADLDADLeslpeYLAlldrleedglpEYEERFKELLNENS--I 845
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2404 QNKSELQdmyeiyksvptqaQKIKEALIETKNAIRDNNKGLYDLKYDmANSVInqikdiyskQLEvATKAYDDEYKAYEK 2483
Cdd:COG4913 846 EFVADLL-------------SKLRRAIREIKERIDPLNDSLKRIPFG-PGRYL---------RLE-ARPRPDPEVREFRQ 901
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2071643352 2484 MINKKLK---LIDDEQTQESFnkdvrdrtEAMDKIRDEIAQRSGDDSLANQKKLKDLREQL 2541
Cdd:COG4913 902 ELRAVTSgasLFDEELSEARF--------AALKRLIERLRSEEEESDRRWRARVLDVRNHL 954
|
|
| CagA_N |
pfam18971 |
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ... |
2459-2633 |
3.08e-04 |
|
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.
Pssm-ID: 408741 [Multi-domain] Cd Length: 876 Bit Score: 46.30 E-value: 3.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2459 IKDIYSKQLEVATKAYDDEYKAYEKMINKKLKLIddEQTQESFNKDVRDRTEAMDKIRDEIAQRSGddslaNQKKLKDLR 2538
Cdd:pfam18971 579 IKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEV--KKAQKDLEKSLRKREHLEKEVEKKLESKSG-----NKNKMEAKA 651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2539 EQLKQQEEDYTMFINNKNRDDRR-------KALQDELNDKNEQIQEQKEDLNKAFQDLI-GDTRRFNAIQESL--MEGQ- 2607
Cdd:pfam18971 652 QANSQKDEIFALINKEANRDARAiaytqnlKGIKRELSDKLEKISKDLKDFSKSFDEFKnGKNKDFSKAEETLkaLKGSv 731
|
170 180 190
....*....|....*....|....*....|....*
gi 2071643352 2608 ---------IDKYKSLIADLTKYVNDNMKEIGRST 2633
Cdd:pfam18971 732 kdlginpewISKVENLNAALNEFKNGKNKDFSKVT 766
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2057-2404 |
4.01e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.08 E-value: 4.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2057 AAMAEDLNEAE------QERLNKIE-QAINAHnKAEEMKQKVDELRKTLMDKQLEEVQTAKEKSENLYNIQKSHVEEYDH 2129
Cdd:COG1196 182 EATEENLERLEdilgelERQLEPLErQAEKAE-RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2130 WRTLQEARSAKLEYELNKIEFEKGRNTKEWRNKNKQLQASRQlEVNFEDSKIQYINKALKKNANKIfgkntvnrdefetm 2209
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-DIARLEERRRELEERLEELEEEL-------------- 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2210 kRDAQQNIRDLKAGIQTASGEIAtsMIDQILDEYEDRVGKVSAKIEKMGKQKEKLDLADNKQALKSSSLSRQQAKDSKSL 2289
Cdd:COG1196 326 -AELEEELEELEEELEELEEELE--EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2290 ASYINFYIKQLERQLKLTGKNHELQQKVKEQIKEMKVAYDDATLAAHQYITEAAE--------VDTERQLQLNANRLRDA 2361
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEeeallellAELLEEAALLEAALAEL 482
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 2071643352 2362 QNELSKADykagfiSQEYQIDLYRKNQEAKFKGYLKEKEALEQ 2404
Cdd:COG1196 483 LEELAEAA------ARLLLLLEAEADYEGFLEGVKAALLLAGL 519
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2063-2589 |
6.45e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 6.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2063 LNEAEQERLNKIEQAINAHNKAEEmKQKVDELRKTLMDKQLEEVQTAKEKSENLYNIQKSHVEEYDHWRTLQEARSAKLE 2142
Cdd:pfam02463 291 LAKEEEELKSELLKLERRKVDDEE-KLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLE 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2143 YELNKIEFEKGRNTKEwrnknKQLQASRQLEVNFEDSKIQYINKALKKNANKIFGKNTVNRDEFETMKRDAQQNIRDLKA 2222
Cdd:pfam02463 370 QLEEELLAKKKLESER-----LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQG 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2223 GIQTASGEIATSMIDQILDEYEDRVGKVSAKIEKMGKQKEKLDLADNKQALKSSSLSRQQAKDSKSLASYINFYIKQLER 2302
Cdd:pfam02463 445 KLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRI 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2303 QLKLTGKNHELQQKVKEQIKEMKVAYDDATLAAHQYITEAAEVDTERQLQLNANRLRDAQNELSKADYKAGFISQEYQID 2382
Cdd:pfam02463 525 ISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILN 604
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2383 LYRKNQ-----------------------EAKFKGYLKEKEALEQNKSELQDMYEIYKSVPTQAQKIKEALIETKNAIRD 2439
Cdd:pfam02463 605 LAQLDKatleadeddkrakvvegilkdteLTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEK 684
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2440 N---NKGLYDLKYDMANSVINQ-IKDIYSKQLEVATKAYDDEYKAYEKMINKKLKLIDDEQTQ------ESFNKDVRDRT 2509
Cdd:pfam02463 685 AeseLAKEEILRRQLEIKKKEQrEKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEeeeeeeKSRLKKEEKEE 764
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2510 EAMDKIRDEIAQRSGDDSLANQKKLKDLREQLKQQEEDytmfINNKNRDDRRKALQDELNDKNEQIQEQKEDLNKAFQDL 2589
Cdd:pfam02463 765 EKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE----LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELAL 840
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2058-2439 |
6.46e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 6.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2058 AMAEDLNEAEQERLNKIEQAINAHNKAEEMKQ----------KVDELRKTLmdKQLEEVQTAKEK-SENLYNIQKSHVEE 2126
Cdd:COG4717 105 EELEAELEELREELEKLEKLLQLLPLYQELEAleaelaelpeRLEELEERL--EELRELEEELEElEAELAELQEELEEL 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2127 YDHWRTLQEARSAKLEYELNKIEFEKGRNTKE-WRNKNKQLQASRQLEVNFEDSKIQYINKALKKNANKIFG-------- 2197
Cdd:COG4717 183 LEQLSLATEEELQDLAEELEELQQRLAELEEElEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIaaallall 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2198 ----------------------------------KNTVNRDEFETMKRDAQQNIRDLKAGIQTASGEIATSMIDQILDEY 2243
Cdd:COG4717 263 glggsllsliltiagvlflvlgllallflllareKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEL 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2244 EDRVGKVSAKIEKMGKQKEKLDLADNKQALKsSSLSRQQAKDSKSLASyinfYIKQLERQLKLTGKNHELQQKVKEQIKE 2323
Cdd:COG4717 343 LDRIEELQELLREAEELEEELQLEELEQEIA-ALLAEAGVEDEEELRA----ALEQAEEYQELKEELEELEEQLEELLGE 417
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2324 MKVAYDDATLAAhqyiTEAAEVDTERQLQLNANRLRDAQNELSKAdykagfisqEYQIDLYRKNQEakfkgYLKEKEALE 2403
Cdd:COG4717 418 LEELLEALDEEE----LEEELEELEEELEELEEELEELREELAEL---------EAELEQLEEDGE-----LAELLQELE 479
|
410 420 430
....*....|....*....|....*....|....*.
gi 2071643352 2404 QNKSELQDMYEIYKSvptqAQKIKEALIETKNAIRD 2439
Cdd:COG4717 480 ELKAELRELAEEWAA----LKLALELLEEAREEYRE 511
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
913-1131 |
7.69e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 45.34 E-value: 7.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 913 QAAEQYKQKQEQTKQAIASMSngEINSLISSYDKLQQKMNSG--SAFNTAEAEKYKEVTSQLANIFPDLVTGENRYGKEM 990
Cdd:TIGR00618 250 EAQEEQLKKQQLLKQLRARIE--ELRAQEAVLEETQERINRArkAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLL 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 991 AGNKEVMKQKIELIKQ---EMELERQKNAIKQKEEQDAYIKEQDS--LAKKNRGQKWYQLGQTPELKLQEQARPTTVSDN 1065
Cdd:TIGR00618 328 MKRAAHVKQQSSIEEQrrlLQTLHSQEIHIRDAHEVATSIREISCqqHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQR 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2071643352 1066 ---------SNINKINATIQKVKSQAQAEKALEQVDKQLAQSQTKNRQNEVQHLQKVRQALQDYITKTGQANQAT 1131
Cdd:TIGR00618 408 eqatidtrtSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIH 482
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
2061-2628 |
1.34e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 44.66 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2061 EDLNEAEQERLNKIEQAINAHNKAEEMKQKVDELRKTLMDkQLEEVQTAKEKSENLYNIQKSH-----VEEYDHWRTLQE 2135
Cdd:TIGR01612 758 EDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYND-QINIDNIKDEDAKQNYDKSKEYiktisIKEDEIFKIINE 836
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2136 ARSAKLEYeLNK----IEFEKGRNTK---------EWRNKNKQLQASRQL---EVNFEDSK--IQYINKALKKNANKIfg 2197
Cdd:TIGR01612 837 MKFMKDDF-LNKvdkfINFENNCKEKidseheqfaELTNKIKAEISDDKLndyEKKFNDSKslINEINKSIEEEYQNI-- 913
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2198 kNTVNR-DEFETMKRDAQQNIRDLKAGiQTASGEIATSMIDQIldeyedrvgKVSAKIEKMGKQKEKLDLADNK----QA 2272
Cdd:TIGR01612 914 -NTLKKvDEYIKICENTKESIEKFHNK-QNILKEILNKNIDTI---------KESNLIEKSYKDKFDNTLIDKIneldKA 982
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2273 LKSSSLSRQQAKDSKsLASYINfyikQLERQLKLTGKNHELQQ---------KVKEQIKEMKVAYDDATLAAHQY---IT 2340
Cdd:TIGR01612 983 FKDASLNDYEAKNNE-LIKYFN----DLKANLGKNKENMLYHQfdekekatnDIEQKIEDANKNIPNIEIAIHTSiynII 1057
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2341 EAAEVDTERQLQ-LNANRLRDAQ------NELSK-------ADY-KAGFISQEYQIDLYR---KNQEAKFKGYLKEKEAL 2402
Cdd:TIGR01612 1058 DEIEKEIGKNIElLNKEILEEAEinitnfNEIKEklkhynfDDFgKEENIKYADEINKIKddiKNLDQKIDHHIKALEEI 1137
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2403 eQNKSE------------LQDMYE--IYKSVPTQAQKIKEAL---IETKNAIRDNNKGLYD--LKYDMANSVINQIKDI- 2462
Cdd:TIGR01612 1138 -KKKSEnyideikaqindLEDVADkaISNDDPEEIEKKIENIvtkIDKKKNIYDEIKKLLNeiAEIEKDKTSLEEVKGIn 1216
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2463 --YSKQL-EVATKAYDDEYKAYEKMINKKLKLIDD-----EQTQESFNKdvrDRTEAMDKIRDEIAQRSGDD-------S 2527
Cdd:TIGR01612 1217 lsYGKNLgKLFLEKIDEEKKKSEHMIKAMEAYIEDldeikEKSPEIENE---MGIEMDIKAEMETFNISHDDdkdhhiiS 1293
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2528 LANQKKLKDLREQLKQQEEDytmFINNKNRDDRRKALQDELNDKneqiQEQKEDLNKAFQDLigdTRRFNAIQESLMEGQ 2607
Cdd:TIGR01612 1294 KKHDENISDIREKSLKIIED---FSEESDINDIKKELQKNLLDA----QKHNSDINLYLNEI---ANIYNILKLNKIKKI 1363
|
650 660
....*....|....*....|.
gi 2071643352 2608 IDKYKSLIADLTKYvNDNMKE 2628
Cdd:TIGR01612 1364 IDEVKEYTKEIEEN-NKNIKD 1383
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
2513-2614 |
1.37e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 43.18 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2513 DKIRDEIAQ---RSGDDSLANQKKLKDLREQLKQQEEDYTMFINNK----NRDDRRKALQDELNDKNEQIQEQKEDLNKA 2585
Cdd:COG4026 106 ELVRKEIKNaiiRAGLKSLQNIPEYNELREELLELKEKIDEIAKEKekltKENEELESELEELREEYKKLREENSILEEE 185
|
90 100
....*....|....*....|....*....
gi 2071643352 2586 FQDLIGDTRRFNAIQESLMEGQIDKYKSL 2614
Cdd:COG4026 186 FDNIKSEYSDLKSRFEELLKKRLLEVFSL 214
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
2058-2573 |
1.41e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 44.12 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2058 AMAEDLNEAEQErLNKIEQAINAHNKAEEMKQKVD-ELRKTLMDKQ--LEEVQTAKEKSENLYNIQKSHV-----EEYDH 2129
Cdd:PRK01156 222 RLSIEYNNAMDD-YNNLKSALNELSSLEDMKNRYEsEIKTAESDLSmeLEKNNYYKELEERHMKIINDPVyknrnYINDY 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2130 WRTLQEARSAK-----LEYELNKIE--FEKGRNTKEWRNKNKQLQaSRQLEVNFEDSKIQYINKALKKNANKIFGKNTVN 2202
Cdd:PRK01156 301 FKYKNDIENKKqilsnIDAEINKYHaiIKKLSVLQKDYNDYIKKK-SRYDDLNNQILELEGYEMDYNSYLKSIESLKKKI 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2203 RDEFETMKRDAQQNIRDLkaGIQTASGEIATSMIDQI---LDEYEDRVGKVSAKIEKMGKQKEklDLADNKQALKSSSL- 2278
Cdd:PRK01156 380 EEYSKNIERMSAFISEIL--KIQEIDPDAIKKELNEInvkLQDISSKVSSLNQRIRALRENLD--ELSRNMEMLNGQSVc 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2279 -----------SRQQAKDSKSLASYINFYIKQLERQLKLTGKNHELQQKVKEQIKEMKVayddatlaaHQYITEAAEVDT 2347
Cdd:PRK01156 456 pvcgttlgeekSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEI---------NKSINEYNKIES 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2348 ERQlqlNANRLRDAQNELSKADYKAGFISQEYQiDLYRKNQEAKFKGYLKEKEA-----LEQNKSELQDMYEIYKSVPTQ 2422
Cdd:PRK01156 527 ARA---DLEDIKIKINELKDKHDKYEEIKNRYK-SLKLEDLDSKRTSWLNALAVislidIETNRSRSNEIKKQLNDLESR 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2423 AQKIkEALIETKNAIRDNNKGLYDlkyDMANSVINQIKDIYSKQLEVATkaYDDEYKAYEKMINKKLKLIDDEQTQESFN 2502
Cdd:PRK01156 603 LQEI-EIGFPDDKSYIDKSIREIE---NEANNLNNKYNEIQENKILIEK--LRGKIDNYKKQIAEIDSIIPDLKEITSRI 676
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2071643352 2503 KDVRDRteaMDKIRDEIaqrsgDDSLANQKKLKDLREQLKQQEEDYTMFINNKNRD-DRRKALQDELNDKNE 2573
Cdd:PRK01156 677 NDIEDN---LKKSRKAL-----DDAKANRARLESTIEILRTRINELSDRINDINETlESMKKIKKAIGDLKR 740
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
2065-2577 |
3.09e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.03 E-value: 3.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2065 EAEQERLNKIEQAinahnkAEEMKQKVDELRKTLMD--KQLEEVQTAKEKSENLYNIQKSHVEEYDHW-RTLQEARSAKL 2141
Cdd:TIGR00618 197 ELLTLRSQLLTLC------TPCMPDTYHERKQVLEKelKHLREALQQTQQSHAYLTQKREAQEEQLKKqQLLKQLRARIE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2142 EYELNKIEFEKGRNTKEWRNKNKQL--QASRQLEVNFedsKIQYINKALKknankifgkntvnrdefETMKRDAQQNIRD 2219
Cdd:TIGR00618 271 ELRAQEAVLEETQERINRARKAAPLaaHIKAVTQIEQ---QAQRIHTELQ-----------------SKMRSRAKLLMKR 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2220 LKAGIQTASGEIATSMIDQILdeyedrvgkvsakiekmgKQKEKLDLADNKQALkssslsrqqakdskslasyinfYIKQ 2299
Cdd:TIGR00618 331 AAHVKQQSSIEEQRRLLQTLH------------------SQEIHIRDAHEVATS----------------------IREI 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2300 LERQLKLTGKNHELQQKV---KEQIKEMKVAYDDATLAAHQYITEAAEvdtERQLQLNANRLRdAQNELSK--ADYKAGF 2374
Cdd:TIGR00618 371 SCQQHTLTQHIHTLQQQKttlTQKLQSLCKELDILQREQATIDTRTSA---FRDLQGQLAHAK-KQQELQQryAELCAAA 446
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2375 ISQEYQIDLYRKNQEAKFKGYLKEKEALEQNKSELQDMYEIYKSVPTQ-AQKIKEALIETKNAIRDNNKGLYDLKYDMAN 2453
Cdd:TIGR00618 447 ITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLArLLELQEEPCPLCGSCIHPNPARQDIDNPGPL 526
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2454 -SVINQIKDIYSKQLEVATKAY---DDEYKAYEKMINKKLKLIDDEQTQESFNKDVRDRTEAMDKIRDEIAQRSGDDSLA 2529
Cdd:TIGR00618 527 tRRMQRGEQTYAQLETSEEDVYhqlTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEA 606
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 2071643352 2530 NQKKLKDLREQLKQQEEDytmfinnknRDDRRKALQDELNDKNEQIQE 2577
Cdd:TIGR00618 607 EDMLACEQHALLRKLQPE---------QDLQDVRLHLQQCSQELALKL 645
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2069-2548 |
3.88e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.83 E-value: 3.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2069 ERLNKIEQAIN-AHNKAEEMKQKVDELRKTlmDKQLEEVQTAKEKSENLYNIQKSHVEEYDHWRTLQEARS--AKLEYEL 2145
Cdd:COG4717 71 KELKELEEELKeAEEKEEEYAELQEELEEL--EEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAelAELPERL 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2146 NKIEfekgrntkewrnknKQLQASRQLEvnfedSKIQYINKALKKNANKIfgkntvnRDEFETMKRDAQQNIRDLKAGIQ 2225
Cdd:COG4717 149 EELE--------------ERLEELRELE-----EELEELEAELAELQEEL-------EELLEQLSLATEEELQDLAEELE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2226 TASGEIATsmIDQILDEYEDRVGKVSAKIEKMGKQKEKLDLADNKQALKSS------------------SLSRQQAKDSK 2287
Cdd:COG4717 203 ELQQRLAE--LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLlliaaallallglggsllSLILTIAGVLF 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2288 SLASYINFYIKQLERQLKLTGKNHELQQKVKEQIKEMKVAYDDatLAAHQYITEAAEVDTERQLQLNANRLRDAQNELSK 2367
Cdd:COG4717 281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEE--LLAALGLPPDLSPEELLELLDRIEELQELLREAEE 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2368 ADykagfisQEYQIDLYRKNQEAKFKGYLKEKEAleqnksELQDMYEIYKsvptQAQKIKEALietknairdnnkglydl 2447
Cdd:COG4717 359 LE-------EELQLEELEQEIAALLAEAGVEDEE------ELRAALEQAE----EYQELKEEL----------------- 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2448 kydmaNSVINQIKDIYSKQLEVATKAYDDEYKAyekminkklKLIDDEQTQESFNKDVRDRTEAMDKIRDEIAQRSGDDS 2527
Cdd:COG4717 405 -----EELEEQLEELLGELEELLEALDEEELEE---------ELEELEEELEELEEELEELREELAELEAELEQLEEDGE 470
|
490 500
....*....|....*....|..
gi 2071643352 2528 LANQK-KLKDLREQLKQQEEDY 2548
Cdd:COG4717 471 LAELLqELEELKAELRELAEEW 492
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
998-1157 |
5.12e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 42.59 E-value: 5.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 998 KQKIELIKQEMELERQKNAIKQKEEQdayikEQDSLAKKNRGQKwyqlgQTPELKLQ-EQARPTTVSDNSNINKINATIQ 1076
Cdd:PRK11281 42 QAQLDALNKQKLLEAEDKLVQQDLEQ-----TLALLDKIDRQKE-----ETEQLKQQlAQAPAKLRQAQAELEALKDDND 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1077 KVKSQAQAEKALEQVDKQLAQsqtknRQNEvqhLQKVRQALQDYITK-TGQANQATRA-AVLTAQQQFTNQIATMKKLGT 1154
Cdd:PRK11281 112 EETRETLSTLSLRQLESRLAQ-----TLDQ---LQNAQNDLAEYNSQlVSLQTQPERAqAALYANSQRLQQIRNLLKGGK 183
|
...
gi 2071643352 1155 TGQ 1157
Cdd:PRK11281 184 VGG 186
|
|
| MARTX_Nterm |
NF012221 |
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ... |
1048-1332 |
5.83e-03 |
|
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.
Pssm-ID: 467957 [Multi-domain] Cd Length: 1848 Bit Score: 42.51 E-value: 5.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1048 TPELKLQEQARPTTVSDNSNINkiNATIQKVKSQAQAEKALEQVDKQLAQSQTKNRQNEVQHLQKVrqalqdyitktGQA 1127
Cdd:NF012221 1537 TSESSQQADAVSKHAKQDDAAQ--NALADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNAL-----------ETN 1603
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1128 NQATRAAVLTAQQQFTNQIATMKklgttgqQVMTTISNSVAKTAKSGKA-----AQATFKSFETSLVKSSSFKSKM---- 1198
Cdd:NF012221 1604 GQAQRDAILEESRAVTKELTTLA-------QGLDALDSQATYAGESGDQwrnpfAGGLLDRVQEQLDDAKKISGKQlada 1676
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1199 -ASYEASVKKFKNAANQSAkiAALKDVERDYSKVAKGIMQAAKAANMSKSQMKDLKKSLQqniQAETGFRASVSKAgkvt 1277
Cdd:NF012221 1677 kQRHVDNQQKVKDAVAKSE--AGVAQGEQNQANAEQDIDDAKADAEKRKDDALAKQNEAQ---QAESDANAAANDA---- 1747
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2071643352 1278 idqsKKIKQNTAETRRNSSAKLQNADASDQASEENKeladSMRAGIESSQLLGKA 1332
Cdd:NF012221 1748 ----QSRGEQDASAAENKANQAQADAKGAKQDESDK----PNRQGAAGSGLSGKA 1794
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
2082-2688 |
6.46e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.93 E-value: 6.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2082 NKAEEMKQKVDELRKtlMDKQLEEVQtaKEKSENLYNIQKSHVEEYDHWRTLQEARSAKLEYELNKIEFEKGRNTKEWRN 2161
Cdd:TIGR04523 114 NDKEQKNKLEVELNK--LEKQKKENK--KNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2162 KNKQLQASRQLEVNFEDSKIQYINKALKKNANKIFGKNTVNRDEFETMkrdaQQNIRDLKAGIQTAsgeiaTSMIDQILD 2241
Cdd:TIGR04523 190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKK----QQEINEKTTEISNT-----QTQLNQLKD 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2242 EYEDRVGKVSAKIEKMGKQKEKL-DLADNKQALKS--SSLSRQQAKD-SKSLASYINFYIKQLERQLKLTGKNHELQQKV 2317
Cdd:TIGR04523 261 EQNKIKKQLSEKQKELEQNNKKIkELEKQLNQLKSeiSDLNNQKEQDwNKELKSELKNQEKKLEEIQNQISQNNKIISQL 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2318 KEQIKEMKVAYDDatlaahqyiTEAAEVDTERQLQLNANRLRDAQNElsKADYKAGFISQEYQIdlyrKNQEAKFKGYLK 2397
Cdd:TIGR04523 341 NEQISQLKKELTN---------SESENSEKQRELEEKQNEIEKLKKE--NQSYKQEIKNLESQI----NDLESKIQNQEK 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2398 EKEALEQNKSELQDMYEIyksVPTQAQKIKEALIETKNAIRDNNKGLYDLKYDMANsvINQIKDIYSKQLEVATKAYDDE 2477
Cdd:TIGR04523 406 LNQQKDEQIKKLQQEKEL---LEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKN--LDNTRESLETQLKVLSRSINKI 480
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2478 YKAYEkmiNKKLKLIDDEQTQESFNKDVRDRTEAMDKIRDEIAQ-RSGDDSLANQK-----KLKDLREQLKQQEEDYTMF 2551
Cdd:TIGR04523 481 KQNLE---QKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSlKEKIEKLESEKkekesKISDLEDELNKDDFELKKE 557
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2552 -----INNKNRD-DRRKALQDELNDKNEQIQEQKEDLNKAFQDLIgdtrrfnaiqeslmeGQIDKYKSLIADLTKYVNDN 2625
Cdd:TIGR04523 558 nlekeIDEKNKEiEELKQTQKSLKKKQEEKQELIDQKEKEKKDLI---------------KEIEEKEKKISSLEKELEKA 622
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2071643352 2626 MKEIGRstsegildgLAASFKGLSSLSKELQKQEKNNLNPVPNSKLKPTKVDEATIAAIKKVN 2688
Cdd:TIGR04523 623 KKENEK---------LSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKID 676
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
6-260 |
6.49e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 42.35 E-value: 6.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 6 NIGILSTLEIDSSSSRKKINDTLKNIEANINSIKADLEVSDTKKSENNAIKSANNVIRNINSN-GNLkkLNVELDVNlTK 84
Cdd:TIGR01612 950 NIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKDASLNDYEAKNNELIKYFNDLKANLGKNkENM--LYHQFDEK-EK 1026
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 85 SRQNIQRALSTLSKDFKNKKIDIEVNAkanKNSIGQVKNSISKGAS--QPLEIKESPSSRSTSRDIKEQQSLMtglansy 162
Cdd:TIGR01612 1027 ATNDIEQKIEDANKNIPNIEIAIHTSI---YNIIDEIEKEIGKNIEllNKEILEEAEINITNFNEIKEKLKHY------- 1096
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 163 kNLDDLTRALNTSTFEGLRKTVKEIKNADNSLKSYQVTLERVNQEGKKLgsqrfdytpsANGLKLNKTQLTDQTDKARKE 242
Cdd:TIGR01612 1097 -NFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENY----------IDEIKAQINDLEDVADKAISN 1165
|
250
....*....|....*....
gi 2071643352 243 ENA-AINKLLENEVSKYDR 260
Cdd:TIGR01612 1166 DDPeEIEKKIENIVTKIDK 1184
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
931-1279 |
7.94e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 41.48 E-value: 7.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 931 SMSNGEINSLISSYDKLQQKMNSGSAFNTAEAEKYKEVTSQLANIFPDLVTGENRYGKEMAGNKEVMKQKIELIKQEM-E 1009
Cdd:COG5185 221 LLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIaE 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1010 LERQ---KNAIKQKEEQDAYIKEQDSLAKKNRGQkwyqlgQTPELKLQEQARPTTVSDNSNINKINATIQKVKS---QAQ 1083
Cdd:COG5185 301 YTKSidiKKATESLEEQLAAAEAEQELEESKRET------ETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGeveLSK 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1084 AEKALEQVDKQLAQSQTKN---RQNEVQHLQKVRQALQDYITKTGQANQATRAAVLTAQQQFTNQIATMKKLGTTGQQVM 1160
Cdd:COG5185 375 SSEELDSFKDTIESTKESLdeiPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVM 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 1161 TTISNSvaKTAKSGKAAQATFKSFETSLVKSSSFKSKMASYEASVKKF--KNAANQSAKIAALKDVERDYSKVAKGIMQA 1238
Cdd:COG5185 455 READEE--SQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATleKLRAKLERQLEGVRSKLDQVAESLKDFMRA 532
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 2071643352 1239 AKAANMSKSQMKDLKKSLQQNIQAETGFRASVSKAGKVTID 1279
Cdd:COG5185 533 RGYAHILALENLIPASELIQASNAKTDGQAANLRTAVIDEL 573
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
2094-2493 |
9.13e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 41.36 E-value: 9.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2094 LRKTlMDKQLEEVQTAKEKSENLyniqksHVEEydhwrTLQEARSAKLEYElNKIEFEkgrntkEWRNKNKQLQASRQLE 2173
Cdd:PRK04778 23 LRKR-NYKRIDELEERKQELENL------PVND-----ELEKVKKLNLTGQ-SEEKFE------EWRQKWDEIVTNSLPD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2174 VNfedskiQYINKALKkNANKI-FGKNTVNRDEFETMKRDAQQNIRDLKAGIQT--ASGEIATSMIDQILDEYEDRVGKV 2250
Cdd:PRK04778 84 IE------EQLFEAEE-LNDKFrFRKAKHEINEIESLLDLIEEDIEQILEELQEllESEEKNREEVEQLKDLYRELRKSL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2251 SAKIEKMGKQKEKLDladnkQALKSSSLSRQQAKDSKSLASYI--NFYIKQLERQLKLTGKN--------HELQQKVKEQ 2320
Cdd:PRK04778 157 LANRFSFGPALDELE-----KQLENLEEEFSQFVELTESGDYVeaREILDQLEEELAALEQImeeipellKELQTELPDQ 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2321 IKEMKVAYDDatLAAHQYITEaaEVDTERQLQLNANRLRDAQNELS-----KADYKAGFISQEyqID-LY---------R 2385
Cdd:PRK04778 232 LQELKAGYRE--LVEEGYHLD--HLDIEKEIQDLKEQIDENLALLEeldldEAEEKNEEIQER--IDqLYdilerevkaR 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2386 KNQEAKFKGYLK-EKEALEQNK------SELQDMYEI-------YKSVPTQAQKIKEALIETKNAIrDNNKGLYDLKYDM 2451
Cdd:PRK04778 306 KYVEKNSDTLPDfLEHAKEQNKelkeeiDRVKQSYTLneselesVRQLEKQLESLEKQYDEITERI-AEQEIAYSELQEE 384
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 2071643352 2452 ANSVINQIKDIYSKQLEVATKA---YDDEYKAYEKMINKKLKLID 2493
Cdd:PRK04778 385 LEEILKQLEEIEKEQEKLSEMLqglRKDELEAREKLERYRNKLHE 429
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2060-2438 |
9.48e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.59 E-value: 9.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2060 AEDLNEAEQERLNKIEQAINAHNKAEEMKQKVDELRKTLMDKQLEEVQTAKEKSENLyniqkshveeydhwrtlqEARSA 2139
Cdd:PRK03918 340 LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEEL------------------EKAKE 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2140 KLEYELNKIEFEKGRNTKEWRNKNKQLQA-----------SRQLEVNFEDSKIQYINKALKKNANKIfgkntvnrDEFET 2208
Cdd:PRK03918 402 EIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvcGRELTEEHRKELLEEYTAELKRIEKEL--------KEIEE 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2209 MKRDAQQNIRDLKAGIQTASGEIATSMIDQILDEYEDRVG-----KVSAKIEKMGKQKEKLDLADNKQALKSSSLSRQQA 2283
Cdd:PRK03918 474 KERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKkynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2284 KDSKSLAsyINFYIKQLERQL-----KLTGKNHELQQKVKEQIKEMKVAYDdatlaahQYITeaaEVDTERQLQLNANRL 2358
Cdd:PRK03918 554 LKKKLAE--LEKKLDELEEELaellkELEELGFESVEELEERLKELEPFYN-------EYLE---LKDAEKELEREEKEL 621
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071643352 2359 RDAQNELSKA-----DYKAGFISQEYQID-LYRKNQEAKFKG----YLKEKEALEQNKSELQDMYEIYKSVPTQAQKIKE 2428
Cdd:PRK03918 622 KKLEEELDKAfeelaETEKRLEELRKELEeLEKKYSEEEYEElreeYLELSRELAGLRAELEELEKRREEIKKTLEKLKE 701
|
410
....*....|
gi 2071643352 2429 ALIETKNAIR 2438
Cdd:PRK03918 702 ELEEREKAKK 711
|
|
| |
