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Conserved domains on  [gi|2072688016|gb|QXX99758|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Mecistops leptorhynchus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.06e-115

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 338.34  E-value: 2.06e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016   1 MPIFQPIILTTLTITTFIFLSSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITT 80
Cdd:MTH00112    2 NPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  81 GNCQIMEMTNQTLMIIMTLAMFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTVSILS 160
Cdd:MTH00112   82 GQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITS 240
Cdd:MTH00112  162 TLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLN 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 241 SLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPTATNTKRLWRKSTQQ 320
Cdd:MTH00112  242 TTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKK 321

                         330       340
                  ....*....|....*....|....*.
gi 2072688016 321 TNLTiNSMATAALTLILAATLMKAIT 346
Cdd:MTH00112  322 NTLT-ATLTTLSTLLLPLSPMILTII 346
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.06e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 338.34  E-value: 2.06e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016   1 MPIFQPIILTTLTITTFIFLSSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITT 80
Cdd:MTH00112    2 NPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  81 GNCQIMEMTNQTLMIIMTLAMFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTVSILS 160
Cdd:MTH00112   82 GQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITS 240
Cdd:MTH00112  162 TLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLN 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 241 SLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPTATNTKRLWRKSTQQ 320
Cdd:MTH00112  242 TTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKK 321

                         330       340
                  ....*....|....*....|....*.
gi 2072688016 321 TNLTiNSMATAALTLILAATLMKAIT 346
Cdd:MTH00112  322 NTLT-ATLTTLSTLLLPLSPMILTII 346
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 21-295 1.25e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 95.57  E-value: 1.25e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIA-SKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNcQIMEMTNQ 91
Cdd:COG1007   120 SANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNLAGIAA-ALAAGGAN 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  92 TLMIIMTLAMFI-----KVGLVPFHFWVPETIQG-MTPTASiFLLTWQKLGPLILL--FLMSPLISFE-----VISTVSI 158
Cdd:COG1007   199 SPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGaPTPVTA-FLATAPKIAAFAALlrLLVEAFPGLAadwqlLLAVLAV 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 159 LSVTVAGWLGLNQTQIRKLVALSSIAQM--AWTIIIIKYAPSLTILAFY--VYSITISTTLLTLEKLSTTSVNSLLLS-- 232
Cdd:COG1007   278 LSMTVGNLAALAQTNVKRMLAYSSIAHAgyLLLGLAAGTPLGVSAALFYllAYLFMNLGAFAVILLLSRKGGEAEEIEdl 357

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2072688016 233 ---FSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:COG1007   358 aglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 22-285 2.89e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 83.90  E-value: 2.89e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  22 STHLVLMWVSLELSTLVVLPLIAS-KSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLM------ 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  95 -----IIMTLAMFIKVGLVPFHFWVPETIQGM-TPTASIFLLTWQKLGPLILLFLMSPLISF-----EVISTVSILSVTV 163
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGApTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 164 AGWLGLNQTQIRKLVALSSIAQMAWTIIII----KYAPSLTILAFYVYSITISTTLL-----TLEKLSTTSVNSLLLSFS 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2072688016 235 KAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMAS 285
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 21-295 3.74e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 82.30  E-value: 3.74e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIA-SKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNCQIMEMTNQ 91
Cdd:TIGR01770 120 SSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFgisliygfTGSLNFEDLLLFLSNGMLNI 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  92 TLMII----MTLAMFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFE-------VISTVSILS 160
Cdd:TIGR01770 200 SLLLLgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILFGfseawqiFLAIIAFLS 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIK-------YAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLS- 232
Cdd:TIGR01770 280 MLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLagtlegiKAVLFYIFIYALMSLGAFGVLSLLRSYKDEWIEYISDFa 359

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2072688016 233 --FSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:TIGR01770 360 glFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.06e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 338.34  E-value: 2.06e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016   1 MPIFQPIILTTLTITTFIFLSSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITT 80
Cdd:MTH00112    2 NPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  81 GNCQIMEMTNQTLMIIMTLAMFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTVSILS 160
Cdd:MTH00112   82 GQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILS 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITS 240
Cdd:MTH00112  162 TLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLN 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 241 SLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPTATNTKRLWRKSTQQ 320
Cdd:MTH00112  242 TTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKK 321

                         330       340
                  ....*....|....*....|....*.
gi 2072688016 321 TNLTiNSMATAALTLILAATLMKAIT 346
Cdd:MTH00112  322 NTLT-ATLTTLSTLLLPLSPMILTII 346
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 21-335 5.04e-83

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 255.50  E-value: 5.04e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMTLA 100
Cdd:MTH00135   22 ASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSHPLPTTMITLA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 101 MFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISfEVISTVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00135  102 LALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNP-TLLITLGLTSTLVGGWGGLNQTQLRKILAY 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 181 SSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00135  181 SSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFM 260

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2072688016 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPTATNTKRLWRKSTQQTNLTINSMATAALTL 335
Cdd:MTH00135  261 PKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQLTLPLAISTTATLML 335
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 21-342 5.27e-81

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 250.61  E-value: 5.27e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMTLA 100
Cdd:MTH00070   22 SSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTGEWTIMNMQTPLPTIMLTIA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 101 MFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00070  102 LMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLSTLIGGWGGLNQTQLRKIMAY 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 181 SSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00070  182 SSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGGLPPTTGFI 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPTATNTKRLWRKSTQQTNLTINSMATAALTLILAAT 340
Cdd:MTH00070  262 PKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNKTNNLLSLTIILSLMLLPITPT 341


                  ..
gi 2072688016 341 LM 342
Cdd:MTH00070  342 IL 343
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 21-342 1.21e-79

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 247.07  E-value: 1.21e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMTLA 100
Cdd:MTH00105   22 ISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTITKLTNPTASTLMTIA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 101 MFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00105  102 LAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLNQTQLRKILAY 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 181 SSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00105  182 SSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLGGLPPLTGFM 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPTATNTKRLWR-KSTQQTNLTINSMATAALTLILAA 339
Cdd:MTH00105  262 PKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQfENTKPMTLLPTLIILSTMLLPLTP 341


                  ...
gi 2072688016 340 TLM 342
Cdd:MTH00105  342 MLS 344
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 21-342 7.54e-67

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 214.06  E-value: 7.54e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMTLA 100
Cdd:MTH00200   22 SSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGISEMLGPLSETLILLA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 101 MFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00200  102 LALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSVLVGGWGGLNQTQLRKILAY 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 181 SSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00200  182 SSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLGGLPPLTGFF 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPTATNTKRLWRKSTQQTNLTINSMATAALTLILAAT 340
Cdd:MTH00200  262 PKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSNSNLLVGLLLLLSILGLPLTPQ 341


                  ..
gi 2072688016 341 LM 342
Cdd:MTH00200  342 LL 343
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 21-325 1.85e-61

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 200.16  E-value: 1.85e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMIIMTLA 100
Cdd:MTH00041   22 SSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNTLSSIIITLA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 101 MFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00041  102 LALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQTRKILAF 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 181 SSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00041  182 SSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTGFL 261

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2072688016 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPPTATNTKRLWRKSTQQTNLTI 325
Cdd:MTH00041  262 NKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGV 326
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 21-299 3.12e-42

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 149.59  E-value: 3.12e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYIttgncqIMEMTNQTLMIIMTLA 100
Cdd:MTH00160   23 SSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML------NLMLFNNISSMLINSS 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 101 MFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMsplISFEVISTVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00160   97 LLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIILSAIIGAIGGLNQTSLRKILAY 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 181 SSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00160  174 SSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFL 253

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2072688016 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNS 299
Cdd:MTH00160  254 PKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSS 292
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 21-336 2.91e-36

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 133.75  E-value: 2.91e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGncqimeMTNQTLMIIMTLA 100
Cdd:MTH00011   24 SSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPS------LLKNITALMLLVS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 101 MFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTVSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00011   98 LMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQLRPLLAY 177

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 181 SSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00011  178 SSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFTGFM 257

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2072688016 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNSASTLPptatNTKRLWRKSTQQTNLTINSMATAALTLI 336
Cdd:MTH00011  258 PKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSP----TFSSLKSAPYEPKTKILISMCTLSLGLI 329
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 21-297 1.14e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 131.93  E-value: 1.14e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNcqimemtnQTLMIIMTLA 100
Cdd:MTH00144   22 SSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFS--------WFSMSLLLLG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 101 MFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILL-FLMSPLISFEVISTVSILSVTVAGWLGLNQTQIRKLVA 179
Cdd:MTH00144   94 LCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLsNFLDLYWLAYLLCVISVLSALVGSIGGLNQTQVRALLA 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 180 LSSIAQMAWTIIIIKYAPSLTILAFYVYSItISTTLLTLEKLSTTSVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGF 259
Cdd:MTH00144  174 YSSISHTGWMLVAILHGSWLMWMYFLIYIV-SSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLLLSLGGLPPFLGF 252

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 2072688016 260 LPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWY 297
Cdd:MTH00144  253 CSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFF 290
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 21-299 6.22e-33

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 124.78  E-value: 6.22e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLnyittgnCQIMEMTNQTLMIIMTLA 100
Cdd:MTH00197   16 SSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSL-------SFSNLYLSLLSVVLVILG 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 101 MFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVIStvSILSVTVAGWLGLNQTQIRKLVAL 180
Cdd:MTH00197   89 LLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLIC--SVLSSLIGGIGGMNQSNIRQLLAY 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 181 SSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFL 260
Cdd:MTH00197  167 SSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLSGFF 246

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2072688016 261 PKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWYNS 299
Cdd:MTH00197  247 LKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 21-295 1.25e-21

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 95.57  E-value: 1.25e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIA-SKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNcQIMEMTNQ 91
Cdd:COG1007   120 SANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYgisllygaTGSLNLAGIAA-ALAAGGAN 198

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  92 TLMIIMTLAMFI-----KVGLVPFHFWVPETIQG-MTPTASiFLLTWQKLGPLILL--FLMSPLISFE-----VISTVSI 158
Cdd:COG1007   199 SPLLLLGLVLVLaglafKLSAVPFHMWTPDVYEGaPTPVTA-FLATAPKIAAFAALlrLLVEAFPGLAadwqlLLAVLAV 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 159 LSVTVAGWLGLNQTQIRKLVALSSIAQM--AWTIIIIKYAPSLTILAFY--VYSITISTTLLTLEKLSTTSVNSLLLS-- 232
Cdd:COG1007   278 LSMTVGNLAALAQTNVKRMLAYSSIAHAgyLLLGLAAGTPLGVSAALFYllAYLFMNLGAFAVILLLSRKGGEAEEIEdl 357

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2072688016 233 ---FSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:COG1007   358 aglARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 21-295 4.70e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 87.01  E-value: 4.70e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHP-RAIEASTKYFLTQATASALMIFSGTLNYITTGNCQI--------MEMTNQ 91
Cdd:MTH00196   11 SSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLsyinlvlnSGQSFS 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  92 TLMI-----IMTLAMFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTvsILSVTVAGW 166
Cdd:MTH00196   91 SVSVpigylLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGG--LFSLFVGAI 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 167 LGLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILAFYVYSI--TISTTLLTLEKLSTTSVNSLLLSFS----KAPITS 240
Cdd:MTH00196  169 GALNQTKIKRLLAYSGIGHMGFVLWGIEIGSFESIQASLVYLFiyIIMSICVFSIILALNVYKNLIIEFSglsrRLPILA 248

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2072688016 241 SLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:MTH00196  249 ITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
21-295 1.06e-18

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 86.80  E-value: 1.06e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIA-SKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNCQIMEMTNQ 91
Cdd:PRK05777  121 SANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYgmsllygaTGSLSFAGIAKALADGSGNS 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  92 TLMII----MTLAMFIKVGLVPFHFWVPETIQGmTPTASI-FLLTWQKL---GPLILLFLMSPL----ISFEVISTVSIL 159
Cdd:PRK05777  201 LLLLFglvfLLVGLAFKLSAVPFHMWTPDVYEG-APTPVTaFLATAPKIaafAVLLRLLVVAFGglseDWQQVLAIIAIA 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 160 SVTVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILAFYVYSITISTT---------LLTLEKLSTTSVNSLL 230
Cdd:PRK05777  280 SMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAYLFMtlgafgvisLLRRKGGEAESISDFA 359

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2072688016 231 LSFSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:PRK05777  360 GLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 22-285 2.89e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 83.90  E-value: 2.89e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  22 STHLVLMWVSLELSTLVVLPLIAS-KSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLM------ 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  95 -----IIMTLAMFIKVGLVPFHFWVPETIQGM-TPTASIFLLTWQKLGPLILLFLMSPLISF-----EVISTVSILSVTV 163
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGApTPVSALLAATLVKAGGYGLIRRSLLYLPSspfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 164 AGWLGLNQTQIRKLVALSSIAQMAWTIIII----KYAPSLTILAFYVYSITISTTLL-----TLEKLSTTSVNSLLLSFS 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2072688016 235 KAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMAS 285
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 21-295 3.74e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 82.30  E-value: 3.74e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIA-SKSHPRAIEASTKYFLTQATASALMIF--------SGTLNYITTGNCQIMEMTNQ 91
Cdd:TIGR01770 120 SSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFgisliygfTGSLNFEDLLLFLSNGMLNI 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  92 TLMII----MTLAMFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFE-------VISTVSILS 160
Cdd:TIGR01770 200 SLLLLgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILFGfseawqiFLAIIAFLS 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 161 VTVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIK-------YAPSLTILAFYVYSITISTTLLTLEKLSTTSVNSLLLS- 232
Cdd:TIGR01770 280 MLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLagtlegiKAVLFYIFIYALMSLGAFGVLSLLRSYKDEWIEYISDFa 359

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2072688016 233 --FSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:TIGR01770 360 glFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRV 424
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 21-295 4.52e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 75.82  E-value: 4.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIA-SKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIME----MTNQTLMI 95
Cdd:MTH00199  115 SSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGinsiLTGDVGKI 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  96 IMTLAMFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTVsiLSVTVAGWLGLNQTQIR 175
Cdd:MTH00199  195 LITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAV--LSIIYGAIGALNQTKIK 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 176 KLVALSSIAQMAWTIIIIKYAPSLTILAFYVYSI--TISTTLLTLEKLSTTSVNSLLLSFS----KAPITSSLLTISLLS 249
Cdd:MTH00199  273 RLLAYSGIGHMGFILFGVAIGSFESIQASLIYMIiyVIMSICSFSIILSLKLTKGLIVEVSglsrKNPVIALTLALTFLS 352

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 2072688016 250 LSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:MTH00199  353 IAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 22-297 6.81e-14

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 72.10  E-value: 6.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  22 STHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIF--------SGTLNY--ITTGNCQIMEMTNQ 91
Cdd:COG0651   126 TGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLgvgllygaTGTLNMadLAARLAELDPGLLL 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  92 TLMIIMTLAMFIKVGLVPFHFWVPET-IQGMTPTASIF--LLTwqKLGPLILL---FLMSPLISFEVISTV----SILSV 161
Cdd:COG0651   206 AAFALLLVGFGIKAALFPLHFWLPDAyPAAPSPVSALLsgLLT--KVGVYAILrvlTLLFGADPALFLGTLllvlGLLTM 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 162 TVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILA--FYVYSITISTTLL------TLEKLSTTSVNSLLLSF 233
Cdd:COG0651   284 LVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGalFHLLNHALAKALLflaagaIERATGTRDLDKLGGLG 363

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2072688016 234 SKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWY 297
Cdd:COG0651   364 KRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFG 427
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 28-297 2.38e-11

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 64.52  E-value: 2.38e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  28 MWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTN--------QTLMIIMTL 99
Cdd:PRK08375  131 LFVFLEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGalaenptvVTAFGFVLL 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 100 AMFIKVGLVPFHFWVPETIQGMTPTASIFL-LTWQKLG--PLILLFL-------MSPLISFEVISTVSILSVTVAGWLGL 169
Cdd:PRK08375  211 ALALKAAVFPLHTWLPRAYPAAPPVVTALLsGLVTKVAvyALIRIYFtvfggdfRFALGLGWLLAVLALLSMLVGSLAAL 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 170 NQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILA--FYV--YSITISTTLLTL----EKLSTTSVNSLLLSFSKAPITSS 241
Cdd:PRK08375  291 GQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAglLHLlhHALMKGALFLAAgaieVTYGTRRLSELSGLGRRMPLTAA 370

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2072688016 242 LLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWY 297
Cdd:PRK08375  371 AFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 21-193 6.40e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 57.26  E-value: 6.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFS---------GTLNYITTGNCQIMEMTNQ 91
Cdd:TIGR01972 124 LALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIYAAMKFFLYTLAGSLLMLLAilglyflggGTFDLLELLNLPLPFGVQT 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  92 TLMIIMTLAMFIKVGLVPFHFWVPET-IQGMTPTASIFLLTWQKLGPLILLFLMSPL------ISFEVISTVSILSVTVA 164
Cdd:TIGR01972 204 WLFLAFFIAFAVKVPLFPLHTWLPDAhVEAPTAGSVILAGVLLKMGTYGFLRFNLPLfpdaslYFAPVLAALGVIAIIYG 283

                         170       180
                  ....*....|....*....|....*....
gi 2072688016 165 GWLGLNQTQIRKLVALSSIAQMAWTIIII 193
Cdd:TIGR01972 284 ALIALAQTDIKRLIAYSSISHMGFVLLGI 312
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 22-295 8.50e-08

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 53.71  E-value: 8.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  22 STHLVLMWVSLELSTLVVLPLIASKSHPRAI---------EASTKYFLTQATASALMIFSGTLNYITTGN--------CQ 84
Cdd:MTH00198  207 SANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegmlgtilSA 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  85 IMEMTNQTL------MIIMTLAMFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLILLflMSPLISFEVISTVSI 158
Cdd:MTH00198  287 TLETTNIELrqgslgYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL--TSLVITSKLLLSVAI 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 159 LSVTVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLL-------TLEKLSTTS------ 225
Cdd:MTH00198  365 ISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTYLVSALasftvicTLEEFGTRTptsrqr 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 226 -------------VNSLLLSFSKaPITSSLLTISLLSLSGLPPLAGFLPKW--------------LTIDQLVAEGAIWIT 278
Cdd:MTH00198  445 dgsfgnynlvrrlVDLTILSRGQ-PYIAFSLAIVFLSLAGIPPLLGFLGKWfilvgsikiafsssLSIYYLVALFAIICT 523

                         330
                  ....*....|....*..
gi 2072688016 279 FVmlmasllSLFFYLRL 295
Cdd:MTH00198  524 CI-------SAFYYIRI 533
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
22-294 5.61e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 51.21  E-value: 5.61e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  22 STHLVLMWVSLE-LSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNY-ITTGNCQIMEM-----TNQTLM 94
Cdd:PRK02504  129 ATELVMIFISLEtLSIASYLLTGYMKRDPRSNEAALKYLLIGAASSAIFLYGSSLLYgLSGGSTQLSAIalaliTSPSLG 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  95 IIMTLAMFI-----KVGLVPFHFWVPETIQGmTPTASI-FLLTWQKLG--PLILLFLMSPLISFE-----VISTVSILSV 161
Cdd:PRK02504  209 LALALVFVIagiafKISAVPFHQWTPDVYEG-SPTPVVaFLSVGSKAAgfALAIRLLVTAFPSFDeqwklLFTALAILSM 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 162 TVAGWLGLNQTQIRKLVALSSIAQMAWTIIII------KYAPSLTILAFYVYSITISTTLLTLEKLSTTS--VNSLLLSF 233
Cdd:PRK02504  288 VLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLvagteaGYASMVFYLLAYLFMNLGAFACVILFSLRTGTdqISDYAGLY 367

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2072688016 234 SKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLR 294
Cdd:PRK02504  368 QKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIR 428
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 25-186 1.70e-06

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 49.69  E-value: 1.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  25 LVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFS----------GTLNYITTGNCQIMEMTNQTLM 94
Cdd:COG1008   133 LFLFYVFWELMLIPMYFLIGIWGGERRIYAAIKFFLYTLAGSLLMLVAilalyflagaLTFDIAELAAAPLPLTAQLLLF 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  95 IIMTLAMFIKVGLVPFHFWVPET-IQGMTPTASIF---LLtwqKLGP---LILLFLMSPLISFE---VISTVSILSVTVA 164
Cdd:COG1008   213 LAFFIAFAVKVPMFPFHTWLPDAhVEAPTAGSVLLagvLL---KMGGyglLRFALPLFPEASAYfapLLAALGVIGIIYG 289

                         170       180
                  ....*....|....*....|..
gi 2072688016 165 GWLGLNQTQIRKLVALSSIAQM 186
Cdd:COG1008   290 ALVALAQTDLKRLIAYSSVSHM 311
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 22-186 4.63e-06

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 48.22  E-value: 4.63e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  22 STHLVLMWVSLELSTLVVLPLIASKSH-PRAIEASTKYFLTQAT------ASALMIFS--GTLNYITTGNcQIMEMTNQT 92
Cdd:COG1009   130 SDNLLLLFVFWELVGLCSYLLIGFWYEkPSARRAARKAFLVTRVgdlgllLGILLLGAiaGTLNFSELLA-AAPTILSSP 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  93 LMIIMTLAMFI----KVGLVPFHFWVPETIQGMTP-----------TASIFLLTwqKLGPLillFLMSPLIsFEVISTVS 157
Cdd:COG1009   209 LLTLILLLLLLgafgKSAQFPLHFWLPDAMEGPTPvsallhaatmvKAGVYLLA--RLSPL---FALSPVW-LTVVAIIG 282

                         170       180
                  ....*....|....*....|....*....
gi 2072688016 158 ILSVTVAGWLGLNQTQIRKLVALSSIAQM 186
Cdd:COG1009   283 AITALFAALIALAQTDIKRVLAYSTVSQL 311
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 22-297 8.59e-06

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 47.30  E-value: 8.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  22 STHLVLMWVSLELSTLVVLPLIASKSHpRAIEASTKYFLTQATASALMIFS--------GTLNYITTGNCQIMEMTNQTL 93
Cdd:PRK08668  117 ANDLLTLYIFWEIMTFSSFMMVPMGKK-ESRKASLKYFVLSAIGAYAMLYAifliyaktGTFDFADISQGLINDTSTGFA 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  94 MII---MTLAMFIKVGLVPFHFWVPETiQGMTPTA--SIFLLTWQKLGPLILLFLMSPL------ISFEVISTVSI---- 158
Cdd:PRK08668  196 LIVflfLLAFGVAKAGIFPLHVWAPDA-YSEAPQSfsAVLSGQLSKLGAYGFLLVLYVLpgtklfSEFGTYRGVPLfnyi 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 159 ------LSVTVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILA--FYVYSITISTTLLTLE------KLSTT 224
Cdd:PRK08668  275 lawlgnISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFAGglFHVFNHALFKGLFFLIfaaviyRTGTT 354

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2072688016 225 SVNSLLLSFSKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRLWY 297
Cdd:PRK08668  355 KISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 21-193 2.42e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 45.96  E-value: 2.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALM----IFSGTLNYITTGNCQI-------MEMT 89
Cdd:PRK05846  129 AALDLLLFYVFFEAMLIPMYFLIGVWGGKNRIYAATKFFLYTLLGSLLMlvaiIYLVVVYYNATGTFDIadllnlpLPPG 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  90 NQTLMIIMTLAMF-IKVGLVPFHFWVPET-IQGMTPTASIFLLTWQKLGPLILL-FL--MSPLISFE---VISTVSILSV 161
Cdd:PRK05846  209 VQYWLFLAFFIAFaVKMPMFPLHTWLPDAhVQAPTAGSVLLAGILLKMGAYGLLrFSlpLFPDASHEfapIIITLGVIAI 288

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2072688016 162 TVAGWLGLNQTQIRKLVALSSIAQMAWTIIII 193
Cdd:PRK05846  289 IYGALVALAQTDIKKLIAYSSISHMGFVTLGI 320
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 22-218 3.54e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 45.52  E-value: 3.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  22 STHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATA------SALMIFSGTLNYITTGNCQIMEMTNQ---- 91
Cdd:PRK08676  121 SDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNWTELAAHasll 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  92 --TLMIIMTLAMFI----KVGLVPFHFWVPETI----QGMTPTASIFLLTWQKLGPLILLFLMSPLISFEVISTV----S 157
Cdd:PRK08676  201 spSVLGASFLFIFIgflaKSGLVPFHTWLPAAYakapSVVSALLSGTVLNIGIYGILRLSALLRQSGAAEQFSNVliglG 280

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2072688016 158 ILSVTVAGWLGLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILAFYVYSITISTTLLTL 218
Cdd:PRK08676  281 IFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHMLAHSLVKSGL 341
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 21-186 5.91e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 44.54  E-value: 5.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  21 SSTHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGN-----------CQIMEMT 89
Cdd:PRK06458  126 TSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTILVYANAATvmgdgemailwTELLKHA 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  90 NQTLMIIMTLA---MFI----KVGLVPFHFWVPET-IQGMTPTASIF----------------LLTWQKLGPLILLFLMs 145
Cdd:PRK06458  206 SLLDPTLMKLAfvfLLIgfgtKVGLFPMHAWLPDAhSEAPSPVSALLsgvllnvalyavlryyILIDAAIGSDFPGRLL- 284

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2072688016 146 plisfeviSTVSILSVTVAGWLGLNQTQIRKLVALSSIAQM 186
Cdd:PRK06458  285 --------LIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHM 317
ndhB CHL00049
NADH dehydrogenase subunit 2
 25-295 7.21e-05

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 44.61  E-value: 7.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  25 LVLMWVSLELSTLVVLPLIA-SKSHPRAIEASTKYFLTQATASALMIFSGTLNY-ITTGNCQIMEMTNQTL--------- 93
Cdd:CHL00049  133 LITIFVALECLSLCSYLLSGyTKKDVRSNEATMKYLLMGGASSSILVYGFSWLYgLSGGEIELQEIVNGLIntqmynspg 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  94 ----MIIMTLAMFIKVGLVPFHFWVPETIQGMTPTASIFLLTWQKLGPLIL----LFLMSPLISFE---VISTVSILSVT 162
Cdd:CHL00049  213 isiaLIFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALatriFDIPFYFSSNEwhlLLEILAILSMI 292

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 163 VAGWLGLNQTQIRKLVALSSIAQMAWTIIII-------KYAPSLTILAFYVYSI--TISTTLLTLEKLSTTSVNSLLLSF 233
Cdd:CHL00049  293 LGNLIAITQTSMKRMLAYSSIGQIGYVIIGIivgdsndGYASMITYMLFYIFMNlgTFACIVLFGLRTGTDNIRDYAGLY 372

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2072688016 234 SKAPITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMASLLSLFFYLRL 295
Cdd:CHL00049  373 TKDPFLALSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 28-195 1.04e-04

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 44.05  E-value: 1.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  28 MWVSLELSTLVVLPLIASKSH-PRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEMTNQTLMI--------IMT 98
Cdd:PRK12649  136 LFIFWELTSITSFMLIGYWRHrPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIATILQDSELIenikghplFLI 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  99 LAMFIKVGLV------PFHFWVPETIQGMTPTASIFLLTWQKLGPLILLFLMSPLIS-----FEVISTVSILSVTVAGWL 167
Cdd:PRK12649  216 TLILIFIGAAaksaqgPFYIWLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPIFSgteawFILVSGTGMITMVLAGFL 295

                         170       180
                  ....*....|....*....|....*...
gi 2072688016 168 GLNQTQIRKLVALSSIAQMAWTIIIIKY 195
Cdd:PRK12649  296 AFRQTDIKAILAYSTISQLAYLMTMYGY 323
PRK12646 PRK12646
DUF4040 family protein;
77-186 5.26e-04

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 42.05  E-value: 5.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  77 YITTGNCQIMEMTNQT-----------LMIIMTLAMFIKVGLVPFHFWVPETIQGMTP-TASIFLLTWQKLGpLILLFLM 144
Cdd:PRK12646  185 YIMTGTNNITEILGQAdhiknhglfipMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPvSAYLHSATMVKAG-IFLLFRF 263

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2072688016 145 SPLISFE-----VISTVSILSVTVAGWLGLNQTQIRKLVALSSIAQM 186
Cdd:PRK12646  264 TPLLGLSnmyiyIVTFVGLITMLFGSITALKQWDLKGILAYSTISQL 310
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
25-203 5.51e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 41.61  E-value: 5.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  25 LVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMI--------FSGTLNY-ITTGNCQIMEMTNQTLMI 95
Cdd:PRK06473  129 LLLFFLFYELELIPLYLLIAIWGGQRRGYAATKFLLYTAISGILILvsflglvwLSGASSFdYEPLRSHTLPLSTQLLLL 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  96 IMTLAMF-IKVGLVPFHFWVPET-IQGMTPTASIFLLTWQKLGPLILL------FLMSPLISFEVISTVSILSVTVAGWL 167
Cdd:PRK06473  209 APILVGFgIKIPLVPFHTWLPDAhVEASTPVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASC 288

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2072688016 168 GLNQTQIRKLVALSSIAQMAWTIIIIKYAPSLTILA 203
Cdd:PRK06473  289 AIAQKDMKKMVAYSSIGHMGYILLAAAAATPLSILA 324
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 52-186 1.12e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 40.82  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  52 IEASTKYFLTQATASALMIFS--------GTLNYITTGNCQIMEMTNQTLMIIMTLAMFIKVGLVPFHFWVPET-----I 118
Cdd:MTH00204  162 VRASYYFFFYTFAGSVFMLLGifqlysitGTTDYQILLNIKLPLSIQKWLLVGFFLSLAVKIPQIPFHIWLPQAhveapV 241

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2072688016 119 QGMTPTASIFLltwqKLGPLILLFLMSPLIS------FEVISTVSILSVTVAGWLGLNQTQIRKLVALSSIAQM 186
Cdd:MTH00204  242 AGSVILAGILL----KLGGYGFLRFSWPLFPaaseyfAPLIVMLSVIAVIYGSLTTCRQVDFKRLIAYSSVAHM 311
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 47-193 1.57e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 40.29  E-value: 1.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  47 SHPRAIEASTKYFLTQATASALMIFS--------GTLNYITTGNCQ--IMEMTNQTLMIIMTLAMFIKVGLVPFHFWVPE 116
Cdd:MTH00226  176 SREEKMQAAYYFFFYTLIGSVLMLLClfslynihGTTDYLTLASCShvVSEQTQKWIFLGIFLAMAVKIPIFPFHIWLPK 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 117 T-----IQGMTPTASIFLltwqKLGPLILLFLMSPLISF------EVISTVSILSVTVAGWLGLNQTQIRKLVALSSIAQ 185
Cdd:MTH00226  256 AhveapVAGSVLLAGILL----KLGGYGLVRLSWPILPLgaqnlaPAVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAH 331


                  ....*...
gi 2072688016 186 MAWTIIII 193
Cdd:MTH00226  332 MGLVSITL 339
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-336 6.07e-03

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 34.54  E-value: 6.07e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2072688016 290 FFYLRLWYNSASTLPPTATNTKRLWRKSTQQTNLTINSMATAALTLI 336
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLL 47
PRK12650 PRK12650
DUF4040 family protein;
25-193 6.84e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.49  E-value: 6.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  25 LVLMWVSLELSTLVVLPLIAsKSHPRAIEASTKYFLTQATASALMIFSGTLNYITTGNCQIMEM---------TNQTLMI 95
Cdd:PRK12650  132 VVVLFVAWELVSLASFFLIA-RSGSGGEAGSIRTLILTFFGGLTLLAAVAIAATQTGTTSLSGIlhsdvwaekPGLTTVV 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  96 IMTLAM--FIKVGLVPFHFWVPETIQGMTPTaSIFL--LTWQKLGpLILLFLMSPLisFEVISTVSILSVTV-------A 164
Cdd:PRK12650  211 AVLIAVaaFTKSAQFPFHFWLPEAMAAITPV-SAFLhaAAVVKAG-IYLLLRFSPV--FHDVAVWNWLLIIVgmitalmG 286

                         170       180
                  ....*....|....*....|....*....
gi 2072688016 165 GWLGLNQTQIRKLVALSSIAQMAWTIIII 193
Cdd:PRK12650  287 AVFAVQKTDLKKLTAYSTVSQLGWIVATI 315
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 22-298 7.01e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 38.26  E-value: 7.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  22 STHLVLMWVSLELSTLVVLPLIASKSHPRAIEASTKYFLTQATASALMIFSGT-LNYITTGN-----CQIMEMTNQTLMI 95
Cdd:PRK06589  135 SSDLFTMFVCYELLTISTAFLIGHTRNNISLSGGYKYLKILMISALLLFLPAViLIYTKTGNldfvsGGLFSKNQSIILL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016  96 IMTLAMFIKVGLVPFHFWVPETIQGMTPTASIF---LLTWQKLGPLILLFLMSPLIS--------FEVISTVSILSVTVA 164
Cdd:PRK06589  215 LMFIYGIAKTAIFPVHSWLPAAMVAHYPVSALLhavIVVKTGLFCIYKILLYIFGLSylqrifaeFNWLIFIPIVSIFYS 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2072688016 165 GWLGLNQTQIRKLVALSSIAQMAWTIII--IKYAPSLTILAFYVYSITISTTLLTL------EKLSTTSVNSLLLSFSKA 236
Cdd:PRK06589  295 SLKALKTDNIKKILAYSTISQLSLALLSafILTPKALGAAILHLVSHSFAKICLFYsmgsiySLKKEDQVDKLHGTSKSF 374

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2072688016 237 PITSSLLTISLLSLSGLPPLAGFLPKWLTIDQLVAEGAIWITFVMLMA----SLLSLFFYLRLWYN 298
Cdd:PRK06589  375 PLISFIISISSLSLIGIPIFSGFISKFLILLAASEQNQPWLSIIVMLVviasSILSALYLLKILSS 440
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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