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Conserved domains on  [gi|2073057211|gb|QYA57041|]
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IS66 family insertion sequence hypothetical protein (plasmid) [Acinetobacter johnsonii]

Protein Classification

transposase( domain architecture ID 11459289)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism; similar to Escherichia coli IS150 protein InsAB

CATH:  1.10.10.10
Gene Ontology:  GO:0006313|GO:0003677|GO:0004803
PubMed:  20885819

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
13-57 8.51e-17

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


:

Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 69.95  E-value: 8.51e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2073057211  13 AKKRRTYSAEFKQQIVQACKAPDVSIASVALQHGLNTNLVSKWIR 57
Cdd:COG2963     2 SKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVR 46
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
13-57 8.51e-17

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 69.95  E-value: 8.51e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2073057211  13 AKKRRTYSAEFKQQIVQACKAPDVSIASVALQHGLNTNLVSKWIR 57
Cdd:COG2963     2 SKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVR 46
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 13-75 8.39e-09

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 48.89  E-value: 8.39e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2073057211  13 AKKRRTYSAEFKQQIVQACKAPDVSIASVALQHGLNTNLVSKWIRLIDGkpGNDRSPLPNKPA 75
Cdd:pfam01527   1 MKKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEG--GMGASPARPRLT 61
transpos_IS3 NF033516
IS3 family transposase;
22-61 8.35e-05

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 40.63  E-value: 8.35e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2073057211  22 EFKQQIVQACKAPDVSIASVALQHGLNTNLVSKWIRLIDG 61
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRG 40
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
13-57 8.51e-17

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 69.95  E-value: 8.51e-17
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2073057211  13 AKKRRTYSAEFKQQIVQACKAPDVSIASVALQHGLNTNLVSKWIR 57
Cdd:COG2963     2 SKKRRRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVR 46
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 13-75 8.39e-09

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 48.89  E-value: 8.39e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2073057211  13 AKKRRTYSAEFKQQIVQACKAPDVSIASVALQHGLNTNLVSKWIRLIDGkpGNDRSPLPNKPA 75
Cdd:pfam01527   1 MKKRRRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEG--GMGASPARPRLT 61
transpos_IS3 NF033516
IS3 family transposase;
22-61 8.35e-05

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 40.63  E-value: 8.35e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2073057211  22 EFKQQIVQACKAPDVSIASVALQHGLNTNLVSKWIRLIDG 61
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYRG 40
HTH_Tnp_ISL3 pfam13542
Helix-turn-helix domain of transposase family ISL3;
11-57 1.52e-04

Helix-turn-helix domain of transposase family ISL3;


Pssm-ID: 463915 [Multi-domain]  Cd Length: 51  Bit Score: 37.06  E-value: 1.52e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2073057211  11 SLAKKRRTYSAEFKQQIVQACKAPdvSIASVALQHGLNTNLVSKWIR 57
Cdd:pfam13542   4 PWARKRSRFTLRFEAYILELLLEM--SVKAVARLLGVSWTTVWRIFD 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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