|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1040 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1101.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 1 MDFSRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 81 KSVAgSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGgkYDSLYMRNYA 160
Cdd:COG0841 81 TSTS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 161 TLKVKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGaeplpkESDFLISINAQ 240
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIG------GGDREYTVRTN 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 241 GRLHTEEEFGNIILKTSqDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRF 320
Cdd:COG0841 232 GRLKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 321 PEDMKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFG 400
Cdd:COG0841 311 PEGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 401 LVLAIGIVVDDAIVVVENVERNIEEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAIST 480
Cdd:COG0841 391 LVLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIAL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 481 VISAINSLTLSPALAALLLKPHGAPKDfptrlidrlfGWIFRPFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLLCAA 560
Cdd:COG0841 471 LISLFVALTLTPALCARLLKPHPKGKK----------GRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALS 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 561 GVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNAlqFTNTPNTGTVFFGLK 640
Cdd:COG0841 541 VLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSG--GGSGSNSGTIFVTLK 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 641 PFDQRKHSAAEINAEINAKIAQIQQGFgFSILPPPILGLGQGSGYSLYIQdraGLGYGALQNAVNTMSGAIMQTPGMHFP 720
Cdd:COG0841 619 PWDERDRSADEIIARLREKLAKIPGAR-VFVFQPPAGGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDV 694
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 721 ISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRNNQG 800
Cdd:COG0841 695 RSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDG 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 801 EMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVlSSAQAMTQLEG-MSKQILPNGMNIEWTDLSFQQATQGNTA 879
Cdd:COG0841 775 EMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGV-SLGEALAAIEElAAELKLPPGVSIEFTGQAEEEQESFSSL 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 880 LIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFARELE 959
Cdd:COG0841 854 GLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLR 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 960 IQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLRKFVT 1039
Cdd:COG0841 934 EEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRR 1013
|
.
gi 1418658187 1040 R 1040
Cdd:COG0841 1014 R 1014
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
3-1049 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1009.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 3 FSRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKS 82
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 83 VAGSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGKYDSLYMRNYATL 162
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 163 KVKDELARLPGVGQIQIFGSgEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGAEPLPKESDFLISINAQGR 242
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 243 LHTEEEFGNIILKTSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPE 322
Cdd:TIGR00915 240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 323 DMKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLV 402
Cdd:TIGR00915 320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 403 LAIGIVVDDAIVVVENVERNI-EEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTV 481
Cdd:TIGR00915 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 482 ISAINSLTLSPALAALLLKPHgaPKDFPTRLIDRLFGWifrpFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLLCAAG 561
Cdd:TIGR00915 480 LSVLVALILTPALCATMLKPI--EKGEHHEKKGGFFGW----FNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMV 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 562 VMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFpGLNALQFT-NTPNTGTVFFGLK 640
Cdd:TIGR00915 554 FLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVF-TVNGFSFAgRGQNMGMAFIRLK 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 641 PFDQRK---HSAAEINAEINAKIAQIQQGFGFSILPPPILGLGQGSGYSLYIQDRAGLGYGALQNAVNTMSGAIMQTPGM 717
Cdd:TIGR00915 633 DWEERTgkeNSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPAL 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 718 HFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRN 797
Cdd:TIGR00915 713 TRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRN 792
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 798 NQGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVlSSAQAMTQLEGMSKQiLPNGMNIEWTDLSFQQATQGN 877
Cdd:TIGR00915 793 ASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGV-STGQAMAAMEAIAQK-LPPGFGFSWTGMSYEERLSGS 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 878 TALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFARE 957
Cdd:TIGR00915 871 QAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKE 950
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 958 LEIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLRKF 1037
Cdd:TIGR00915 951 LMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRL 1030
|
1050
....*....|..
gi 1418658187 1038 VTRGKEEREVLP 1049
Cdd:TIGR00915 1031 FKRKAHEKEMSV 1042
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1035 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 987.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 3 FSRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 83 VAgSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGKYDSLYMRNYATL 162
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 163 KVKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLgaeplpKESDFLISINAQGR 242
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 243 LHTEEEFGNIILKtSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPE 322
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 323 DMKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLV 402
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 403 LAIGIVVDDAIVVVENVERNIEE-GLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTV 481
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 482 ISAINSLTLSPALAALLLKPHGAPKDfptrlidrlfGWIFRPFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLLCAAG 561
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKH----------GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSV 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 562 VMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNALQFTNTPNTGTVFFGLKP 641
Cdd:pfam00873 543 WLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISLKP 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 642 FDQRKH---SAAEINAEINAKIAQIQQGFGFSILPPPILGLGQGSGYSLYIQD-RAGLGYGALQNAVNTMSGAIMQTPGM 717
Cdd:pfam00873 623 WKERPGpekSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPGL 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 718 HFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRN 797
Cdd:pfam00873 703 SDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRN 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 798 NQGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVLSSaQAMTQLEGMSKQI-LPNGMNIEWTDLSFQQATQG 876
Cdd:pfam00873 783 PYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLG-DAMEAMAQIAKQVkLPPGYGYTWTGQFEQEQLAG 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 877 NTALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFAR 956
Cdd:pfam00873 862 NSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFAN 941
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 957 EL-EIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLR 1035
Cdd:pfam00873 942 ELrEQEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
4-1042 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 816.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 4 SRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMkSV 83
Cdd:PRK09577 2 ARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYT-SA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 84 AGSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGKYDSLYMRNYATLK 163
Cdd:PRK09577 81 TSSAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 164 VKDELARLPGVGQIQIFGSgEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGAEPLPKESDFLISINAQGRL 243
Cdd:PRK09577 161 VLQALRRVEGVGKVQFWGA-EYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 244 HTEEEFGNIILKTSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPED 323
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 324 MKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLVL 403
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 404 AIGIVVDDAIVVVENVER-NIEEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTVI 482
Cdd:PRK09577 400 AIGILVDDAIVVVENVERlMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 483 SAINSLTLSPALAALLLKP----HGAPKDFptrlidrlFGWifrpFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLLC 558
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPvdgdHHEKRGF--------FGW----FNRFVARSTQRYATRVGAILKRPLRWLVVYGALTA 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 559 AAGVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNAlqFTNTPNTGTVFFG 638
Cdd:PRK09577 548 AAALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNL--YGEGPNGGMIFVT 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 639 LKPFDQRKHSAAEINA---EINAKIAQIQQGFGFSILPPPILGLGQGSGYSLYIQDRAGLGYGALQNAVNTMSGAIMQTP 715
Cdd:PRK09577 626 LKDWKERKAARDHVQAivaRINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDP 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 716 GMHFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRT 795
Cdd:PRK09577 706 ALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRV 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 796 RNNQGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRvLSSAQAMTQLEGMSKQiLPNGMNIEWTDLSFQQATQ 875
Cdd:PRK09577 786 RNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPG-HSSGEAMAAIERIAAT-LPAGIGYAWSGQSFEERLS 863
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 876 GNTALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFA 955
Cdd:PRK09577 864 GAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVA 943
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 956 RELEIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLR 1035
Cdd:PRK09577 944 KDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVG 1023
|
....*..
gi 1418658187 1036 KFVTRGK 1042
Cdd:PRK09577 1024 RLFDVGP 1030
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1031 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 661.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 4 SRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKSV 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 84 AgSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGkYDSLYMRNYATLK 163
Cdd:NF033617 81 S-SLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEE-MPRGQLTDYAERV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 164 VKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLgaeplpKESDFLISINAQGRL 243
Cdd:NF033617 159 LAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAV------RGDSVVSTVRANDQL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 244 HTEEEFGNIILKTSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPED 323
Cdd:NF033617 233 KTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 324 MKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLVL 403
Cdd:NF033617 313 IKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 404 AIGIVVDDAIVVVENVERNIEEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTVIS 483
Cdd:NF033617 393 AIGLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 484 AINSLTLSPALAALLLKPHGAPKDFpTRLIDRLFGWIfrpfnrffhrsSTGYQGLVGKTLGRRGAVFVVYLLLLCAAGVM 563
Cdd:NF033617 473 GIVALTLTPMMCSRLLKANEKPGRF-ARAVDRFFDGL-----------TARYGRGLKWVLKHRPLTLVVALATLALLPLL 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 564 FKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNAlqfTNTPNTGTVFFGLKPFD 643
Cdd:NF033617 541 YVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGG---NPGDNTGFGIINLKPWD 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 644 QRKHSAAEINAEINAKIAQIqQGFGFSILPPPILGLGQGSGYSLYIQDRAGLGYGALQNAVNTMSGAIMQTPGMHFPIST 723
Cdd:NF033617 618 ERDVSAQEIIDRLRPKLAKV-PGMDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSD 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 724 YQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRNNQGEMV 803
Cdd:NF033617 697 LQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLV 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 804 PIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVlSSAQAMTQLEGMSKQILPNGMNIEWTDLSFQQATQGNTALIVF 883
Cdd:NF033617 777 PLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGV-SLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLFLF 855
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 884 PVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFARELEI-QG 962
Cdd:NF033617 856 LLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRhQG 935
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1418658187 963 KGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFY 1031
Cdd:NF033617 936 LSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVY 1004
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1040 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1101.70 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 1 MDFSRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 81 KSVAgSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGgkYDSLYMRNYA 160
Cdd:COG0841 81 TSTS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 161 TLKVKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGaeplpkESDFLISINAQ 240
Cdd:COG0841 158 ERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIG------GGDREYTVRTN 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 241 GRLHTEEEFGNIILKTSqDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRF 320
Cdd:COG0841 232 GRLKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 321 PEDMKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFG 400
Cdd:COG0841 311 PEGVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 401 LVLAIGIVVDDAIVVVENVERNIEEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAIST 480
Cdd:COG0841 391 LVLAIGIVVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIAL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 481 VISAINSLTLSPALAALLLKPHGAPKDfptrlidrlfGWIFRPFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLLCAA 560
Cdd:COG0841 471 LISLFVALTLTPALCARLLKPHPKGKK----------GRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALS 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 561 GVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNAlqFTNTPNTGTVFFGLK 640
Cdd:COG0841 541 VLLFGRLPTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSG--GGSGSNSGTIFVTLK 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 641 PFDQRKHSAAEINAEINAKIAQIQQGFgFSILPPPILGLGQGSGYSLYIQdraGLGYGALQNAVNTMSGAIMQTPGMHFP 720
Cdd:COG0841 619 PWDERDRSADEIIARLREKLAKIPGAR-VFVFQPPAGGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIPGLVDV 694
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 721 ISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRNNQG 800
Cdd:COG0841 695 RSDLQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDG 774
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 801 EMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVlSSAQAMTQLEG-MSKQILPNGMNIEWTDLSFQQATQGNTA 879
Cdd:COG0841 775 EMVPLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGV-SLGEALAAIEElAAELKLPPGVSIEFTGQAEEEQESFSSL 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 880 LIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFARELE 959
Cdd:COG0841 854 GLAFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLR 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 960 IQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLRKFVT 1039
Cdd:COG0841 934 EEGMSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRR 1013
|
.
gi 1418658187 1040 R 1040
Cdd:COG0841 1014 R 1014
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
3-1049 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1009.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 3 FSRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKS 82
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 83 VAGSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGKYDSLYMRNYATL 162
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 163 KVKDELARLPGVGQIQIFGSgEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGAEPLPKESDFLISINAQGR 242
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 243 LHTEEEFGNIILKTSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPE 322
Cdd:TIGR00915 240 LQTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 323 DMKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLV 402
Cdd:TIGR00915 320 GMKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 403 LAIGIVVDDAIVVVENVERNI-EEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTV 481
Cdd:TIGR00915 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 482 ISAINSLTLSPALAALLLKPHgaPKDFPTRLIDRLFGWifrpFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLLCAAG 561
Cdd:TIGR00915 480 LSVLVALILTPALCATMLKPI--EKGEHHEKKGGFFGW----FNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMV 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 562 VMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFpGLNALQFT-NTPNTGTVFFGLK 640
Cdd:TIGR00915 554 FLFVRLPTSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVF-TVNGFSFAgRGQNMGMAFIRLK 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 641 PFDQRK---HSAAEINAEINAKIAQIQQGFGFSILPPPILGLGQGSGYSLYIQDRAGLGYGALQNAVNTMSGAIMQTPGM 717
Cdd:TIGR00915 633 DWEERTgkeNSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPAL 712
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 718 HFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRN 797
Cdd:TIGR00915 713 TRVRPNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRN 792
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 798 NQGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVlSSAQAMTQLEGMSKQiLPNGMNIEWTDLSFQQATQGN 877
Cdd:TIGR00915 793 ASGEMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGV-STGQAMAAMEAIAQK-LPPGFGFSWTGMSYEERLSGS 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 878 TALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFARE 957
Cdd:TIGR00915 871 QAPALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKE 950
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 958 LEIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLRKF 1037
Cdd:TIGR00915 951 LMAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRL 1030
|
1050
....*....|..
gi 1418658187 1038 VTRGKEEREVLP 1049
Cdd:TIGR00915 1031 FKRKAHEKEMSV 1042
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1035 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 987.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 3 FSRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 83 VAgSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGKYDSLYMRNYATL 162
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 163 KVKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLgaeplpKESDFLISINAQGR 242
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 243 LHTEEEFGNIILKtSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPE 322
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 323 DMKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLV 402
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 403 LAIGIVVDDAIVVVENVERNIEE-GLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTV 481
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 482 ISAINSLTLSPALAALLLKPHGAPKDfptrlidrlfGWIFRPFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLLCAAG 561
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKH----------GGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSV 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 562 VMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNALQFTNTPNTGTVFFGLKP 641
Cdd:pfam00873 543 WLFVRIPTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGDNNGPNSGDAFISLKP 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 642 FDQRKH---SAAEINAEINAKIAQIQQGFGFSILPPPILGLGQGSGYSLYIQD-RAGLGYGALQNAVNTMSGAIMQTPGM 717
Cdd:pfam00873 623 WKERPGpekSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPGL 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 718 HFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRN 797
Cdd:pfam00873 703 SDVRSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRN 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 798 NQGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVLSSaQAMTQLEGMSKQI-LPNGMNIEWTDLSFQQATQG 876
Cdd:pfam00873 783 PYGKMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLG-DAMEAMAQIAKQVkLPPGYGYTWTGQFEQEQLAG 861
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 877 NTALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFAR 956
Cdd:pfam00873 862 NSLPILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFAN 941
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 957 EL-EIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLR 1035
Cdd:pfam00873 942 ELrEQEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
4-1042 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 816.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 4 SRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMkSV 83
Cdd:PRK09577 2 ARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYT-SA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 84 AGSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGKYDSLYMRNYATLK 163
Cdd:PRK09577 81 TSSAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 164 VKDELARLPGVGQIQIFGSgEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGAEPLPKESDFLISINAQGRL 243
Cdd:PRK09577 161 VLQALRRVEGVGKVQFWGA-EYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 244 HTEEEFGNIILKTSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPED 323
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 324 MKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLVL 403
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 404 AIGIVVDDAIVVVENVER-NIEEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTVI 482
Cdd:PRK09577 400 AIGILVDDAIVVVENVERlMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 483 SAINSLTLSPALAALLLKP----HGAPKDFptrlidrlFGWifrpFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLLC 558
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPvdgdHHEKRGF--------FGW----FNRFVARSTQRYATRVGAILKRPLRWLVVYGALTA 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 559 AAGVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNAlqFTNTPNTGTVFFG 638
Cdd:PRK09577 548 AAALLFTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNL--YGEGPNGGMIFVT 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 639 LKPFDQRKHSAAEINA---EINAKIAQIQQGFGFSILPPPILGLGQGSGYSLYIQDRAGLGYGALQNAVNTMSGAIMQTP 715
Cdd:PRK09577 626 LKDWKERKAARDHVQAivaRINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDP 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 716 GMHFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRT 795
Cdd:PRK09577 706 ALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRV 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 796 RNNQGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRvLSSAQAMTQLEGMSKQiLPNGMNIEWTDLSFQQATQ 875
Cdd:PRK09577 786 RNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPG-HSSGEAMAAIERIAAT-LPAGIGYAWSGQSFEERLS 863
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 876 GNTALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFA 955
Cdd:PRK09577 864 GAQAPMLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVA 943
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 956 RELEIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLR 1035
Cdd:PRK09577 944 KDLVAQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVG 1023
|
....*..
gi 1418658187 1036 KFVTRGK 1042
Cdd:PRK09577 1024 RLFDVGP 1030
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
4-1036 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 812.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 4 SRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKSV 83
Cdd:PRK10555 2 ANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 84 AGSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGKYDSLYMRNYATLK 163
Cdd:PRK10555 82 SSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 164 VKDELARLPGVGQIQIFGSgEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGAEPLPKESDFLISINAQGRL 243
Cdd:PRK10555 162 IQDPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 244 HTEEEFGNIILKTSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPED 323
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 324 MKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLVL 403
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 404 AIGIVVDDAIVVVENVERNI-EEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTVI 482
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 483 SAINSLTLSPALAALLLKP-----HGAPKDFptrlidrlFGWifrpFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLL 557
Cdd:PRK10555 481 SVLVAMILTPALCATLLKPlkkgeHHGQKGF--------FGW----FNRMFNRNAERYEKGVAKILHRSLRWILIYVLLL 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 558 CAAGVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNALQFTNTPNTGTVFF 637
Cdd:PRK10555 549 GGMVFLFLRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFI 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 638 GLKPFDQRK---HSAAEINAEINAKIAQIQQGFGFSILPPPILGLGQGSGYSLYIQDRAGLGYGALQNAVNTMSGAIMQT 714
Cdd:PRK10555 629 RLKDWDERDsktGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKN 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 715 PGMHFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLR 794
Cdd:PRK10555 709 PELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWY 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 795 TRNNQGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVlSSAQAMTQLEGMSKQiLPNGMNIEWTDLSFQQAT 874
Cdd:PRK10555 789 VRNKDGGMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGV-STGTAMDIMESLVKQ-LPNGFGLEWTAMSYQERL 866
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 875 QGNTALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEF 954
Cdd:PRK10555 867 SGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEF 946
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 955 ARELEIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTL 1034
Cdd:PRK10555 947 ANEMNQKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLV 1026
|
..
gi 1418658187 1035 RK 1036
Cdd:PRK10555 1027 RR 1028
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
4-1046 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 806.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 4 SRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKSV 83
Cdd:PRK15127 2 PNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 84 AGSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGKYDSLYMRNYATLK 163
Cdd:PRK15127 82 SDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAAN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 164 VKDELARLPGVGQIQIFGSgEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGAEPLPKESDFLISINAQGRL 243
Cdd:PRK15127 162 MKDPISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 244 HTEEEFGNIILKTSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPED 323
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 324 MKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLVL 403
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 404 AIGIVVDDAIVVVENVERNI-EEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTVI 482
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 483 SAINSLTLSPALAALLLKP-----HGAPKdfptrliDRLFGWifrpFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLL 557
Cdd:PRK15127 481 SVLVALILTPALCATMLKPiakgdHGEGK-------KGFFGW----FNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIV 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 558 CAAGVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFpGLNALQFT-NTPNTGTVF 636
Cdd:PRK15127 550 VGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVF-AVNGFGFAgRGQNTGIAF 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 637 FGLKPFDQRKHSAAEINA---EINAKIAQIQQGFGFSILPPPILGLGQGSGYSLYIQDRAGLGYGALQNAVNTMSGAIMQ 713
Cdd:PRK15127 629 VSLKDWADRPGEENKVEAitmRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAK 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 714 TPGMhfpISTYQAN----VPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVED 789
Cdd:PRK15127 709 HPDM---LVGVRPNgledTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDD 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 790 IANLRTRNNQGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVlSSAQAMTQLEGMSKQiLPNGMNIEWTDLS 869
Cdd:PRK15127 786 IGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGK-STGEAMELMEELASK-LPTGVGYDWTGMS 863
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 870 FQQATQGNTALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAI 949
Cdd:PRK15127 864 YQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAI 943
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 950 LIVEFAREL-EIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTP 1028
Cdd:PRK15127 944 LIVEFAKDLmDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVP 1023
|
1050
....*....|....*...
gi 1418658187 1029 VFYVTLRKFVTRGKEERE 1046
Cdd:PRK15127 1024 VFFVVVRRRFSRKNEDIE 1041
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1031 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 661.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 4 SRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKSV 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 84 AgSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSPGGkYDSLYMRNYATLK 163
Cdd:NF033617 81 S-SLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEE-MPRGQLTDYAERV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 164 VKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLgaeplpKESDFLISINAQGRL 243
Cdd:NF033617 159 LAPKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAV------RGDSVVSTVRANDQL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 244 HTEEEFGNIILKTSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPED 323
Cdd:NF033617 233 KTAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 324 MKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLVL 403
Cdd:NF033617 313 IKVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 404 AIGIVVDDAIVVVENVERNIEEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTVIS 483
Cdd:NF033617 393 AIGLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 484 AINSLTLSPALAALLLKPHGAPKDFpTRLIDRLFGWIfrpfnrffhrsSTGYQGLVGKTLGRRGAVFVVYLLLLCAAGVM 563
Cdd:NF033617 473 GIVALTLTPMMCSRLLKANEKPGRF-ARAVDRFFDGL-----------TARYGRGLKWVLKHRPLTLVVALATLALLPLL 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 564 FKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNAlqfTNTPNTGTVFFGLKPFD 643
Cdd:NF033617 541 YVFIPKELAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGG---NPGDNTGFGIINLKPWD 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 644 QRKHSAAEINAEINAKIAQIqQGFGFSILPPPILGLGQGSGYSLYIQDRAGLGYGALQNAVNTMSGAIMQTPGMHFPIST 723
Cdd:NF033617 618 ERDVSAQEIIDRLRPKLAKV-PGMDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSD 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 724 YQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRNNQGEMV 803
Cdd:NF033617 697 LQDKGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLV 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 804 PIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVlSSAQAMTQLEGMSKQILPNGMNIEWTDLSFQQATQGNTALIVF 883
Cdd:NF033617 777 PLSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGV-SLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLFLF 855
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 884 PVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFARELEI-QG 962
Cdd:NF033617 856 LLALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRhQG 935
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1418658187 963 KGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFY 1031
Cdd:NF033617 936 LSRREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVY 1004
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-1036 |
9.12e-158 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 493.58 E-value: 9.12e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 1 MDFSRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 81 KSVAGSDgVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQKQSPTLTLVVHLFSpgGKYDSLYMRNYA 160
Cdd:PRK09579 81 TSVSRQN-FSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYS--EEMSNPQITDYL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 161 TLKVKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGAEPLpkesdfLISINAQ 240
Cdd:PRK09579 158 SRVIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYV------VTSINAS 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 241 GRLHTEEEFGNIILKTSQDgSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRF 320
Cdd:PRK09579 232 TELKSAEAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 321 PEDMKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFG 400
Cdd:PRK09579 311 PPNLKVSIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLA 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 401 LVLAIGIVVDDAIVVVENVERNIEEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAIST 480
Cdd:PRK09579 391 MVLAIGLVVDDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAV 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 481 VISAINSLTLSPALAALLLKPHGAPKDFPTRLidrlfgwifrpfNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLLCAA 560
Cdd:PRK09579 471 IISGIVALTLSPMMCALLLRHEENPSGLAHRL------------DRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALI 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 561 GVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNALQftntpnTGTVFFGLK 640
Cdd:PRK09579 539 PVLLKFTQSELAPEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQ------SGIGGFLLK 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 641 PFDQRKHSAAEINAEINAKIAQIQ--QGFGFSIlpPPILGLGQGSGYSLYIQDRAglGYGALQNAVNTMSGAIMQTPGMH 718
Cdd:PRK09579 613 PWNERERTQMELLPLVQAKLEEIPglQIFGFNL--PSLPGTGEGLPFQFVINTAN--DYESLLQVAQRVKQRAQESGKFA 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 719 FPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRNN 798
Cdd:PRK09579 689 FLDIDLAFDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNE 768
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 799 QGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDAdprVLSSAQAMTQLEGMSKQILPNGMNIEWTDLSFQQATQGNT 878
Cdd:PRK09579 769 QGQLLPLSTLITLSDRARPRQLNQFQQLNSAIISGFP---IVSMGEAIETVQQIAREEAPEGFAFDYAGASRQYVQEGSA 845
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 879 ALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFAREL 958
Cdd:PRK09579 846 LWVTFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQL 925
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1418658187 959 -EIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLRK 1036
Cdd:PRK09579 926 rHEQGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAK 1004
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
5-1044 |
1.24e-113 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 376.29 E-value: 1.24e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 5 RFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKSVA 84
Cdd:COG3696 7 RFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 85 GSdGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVR-RLG-ITTqkqsPT-----LTLVvhlfSPGGKYDSLYMR 157
Cdd:COG3696 87 RF-GLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTpELGpIST----GLgeiyqYTLE----SDPGKYSLMELR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 158 NYATLKVKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQL---GAEplpkesdfl 234
Cdd:COG3696 158 TLQDWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIergGQE--------- 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 235 ISINAQGRLHTEEEFGNIILKTsQDGSLVRLRDVARIEMGSgsyALR----SQLNNKDAVGIGIFQSPGANAIDLSNAVR 310
Cdd:COG3696 229 YLVRGIGLIRSLEDIENIVVKT-RNGTPVLLRDVAEVRIGP---APRrgaaTLNGEGEVVGGIVLMLKGENALEVIEAVK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 311 AKMAELSTRFPEDMKWAAPYDPTVFVRDSIRAVvqtlleavvlvvlvvilflQT-------------------WRASIIP 371
Cdd:COG3696 305 AKLAELKPSLPEGVKIVPFYDRSDLIDRAIHTV-------------------TKnllegallvilvlflflgnLRAALIV 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 372 LIAVPVSVVGTFSVLYLLGFSLNTLSLFGLVLAIGIVVDDAIVVVENVERNIEE------GLAPLAAAHQAMREVSGPII 445
Cdd:COG3696 366 ALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDFGIIVDGAVVMVENILRRLEEnraagtPRERLEVVLEAAREVRRPIF 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 446 AIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTVISAINSLTLSPALAALLLKPHGAPKDfptrlidrlfgwifRPFN 525
Cdd:COG3696 446 FATLIIILVFLPIFTLEGVEGKLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKE--------------NPLV 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 526 RFFHRsstGYQGLVGKTLGRRGAVFVVYLLLLCAAGVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEI 605
Cdd:COG3696 512 RWLKR---LYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERI 588
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 606 GMNTEGVDYAVAFPGlnalqftnTPNTGT---------VFFGLKPFDQ--RKHSAAEINAEINAKIAQIqQGFGFSILPP 674
Cdd:COG3696 589 LKSFPEVESVVSRTG--------RAEDATdpmgvnmseTFVILKPRSEwrSGRTKEELIAEMREALEQI-PGVNFNFSQP 659
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 675 pilglgqgsgyslyIQDR---------AGLG---YG-----------ALQNAVNTMSGA----IMQTPGmhfpistyqan 727
Cdd:COG3696 660 --------------IQMRvdellsgvrADVAvkiFGddldvlrrlaeQIEAVLKTVPGAadvqVERVTG----------- 714
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 728 VPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTRNNQGEMVPIGS 807
Cdd:COG3696 715 LPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQ 794
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 808 MVKISTTYGPDPVIRYNGYPAADLIGDADPRVLSS--AQAMTQLEgmsKQI-LPNGMNIEWTDL--SFQQATQgnTALIV 882
Cdd:COG3696 795 VADIEVVEGPNQISRENGRRRIVVQANVRGRDLGSfvAEAQAKVA---EQVkLPPGYYIEWGGQfeNLQRATA--RLAIV 869
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 883 FPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFARELEIQG 962
Cdd:COG3696 870 VPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEG 949
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 963 KGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYVTLRKFVTRGK 1042
Cdd:COG3696 950 LDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLRRA 1029
|
..
gi 1418658187 1043 EE 1044
Cdd:COG3696 1030 AA 1031
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
4-1032 |
4.32e-109 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 364.05 E-value: 4.32e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 4 SRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKSV 83
Cdd:PRK10503 13 SRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 84 AgSDGVLVTTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGITTQ---KQSPTLTLVVhlfspggKYDSLYMRNYA 160
Cdd:PRK10503 93 S-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKvnpADPPIMTLAV-------TSTAMPMTQVE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 161 TL---KVKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLGAeplPKESdflISI 237
Cdd:PRK10503 165 DMvetRVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDG---PTRA---VTL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 238 NAQGRLHTEEEFGNIILkTSQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELS 317
Cdd:PRK10503 239 SANDQMQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLT 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 318 TRFPEDMKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLS 397
Cdd:PRK10503 318 ESLPKSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLT 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 398 LFGLVLAIGIVVDDAIVVVENVERNIEEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIA 477
Cdd:PRK10503 398 LMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLA 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 478 ISTVISAINSLTLSPALAALLLKPHGAPKDfptrliDRLfgwiFRPFNRFFHRSSTGYQGLVGKTLGRRGAVFVVYLLLL 557
Cdd:PRK10503 478 VAILISAVVSLTLTPMMCARMLSQESLRKQ------NRF----SRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 558 CAAGVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNAlqfTN-TPNTGTVF 636
Cdd:PRK10503 548 LLTVLLWIFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDG---TNpSLNSARLQ 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 637 FGLKPFDQRKHSAAEINAEINAKIAQIqQGFGFSILPPPILGLGQGSGYSLYIQDRAGLGYGALQNAVNTMSGAIMQTPG 716
Cdd:PRK10503 625 INLKPLDERDDRVQKVIARLQTAVAKV-PGVDLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQ 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 717 MHFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYRESVEDIANLRTR 796
Cdd:PRK10503 704 LSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLT 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 797 NNQGEMVPIGSMVKISTTYGPDPVIRYNGYPAADLIGDAdPRVLSSAQAMTQLEGMSKQI-LPNGMNIEW--TDLSFQQA 873
Cdd:PRK10503 784 SSDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNV-PDGYSLGDAVQAIMDTEKTLnLPADITTQFqgSTLAFQSA 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 874 TQGNTALIVfpVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVE 953
Cdd:PRK10503 863 LGSTVWLIV--AAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMID 940
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 954 FARELE-IQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLFLTPVFYV 1032
Cdd:PRK10503 941 FALAAErEQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYL 1020
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
1-1046 |
1.07e-107 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 359.81 E-value: 1.07e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 1 MDFSRFFIDRPIFAAVLSILIFITGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEA---INGVENM 77
Cdd:PRK10614 1 MKFFALFIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSlgrIAGVNEM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 78 MYMKSVAGSDGVLVttvtFRPGTDPDQAQVQVQNRVAQAEARLPEDVRRLGiTTQKQSPT------LTLVVHLFSPGGKY 151
Cdd:PRK10614 81 TSSSSLGSTRIILQ----FDFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKANPSdapimiLTLTSDTYSQGQLY 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 152 DslymrnYATLKVKDELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQLgaeplpKES 231
Cdd:PRK10614 156 D------FASTQLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAV------EDG 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 232 DFLISINAQGRLHTEEEFGNIILKTsQDGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRA 311
Cdd:PRK10614 224 THRWQIQTNDELKTAAEYQPLIIHY-NNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 312 KMAELSTRFPE--DMKWAAPYDPTVfvRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLL 389
Cdd:PRK10614 303 KLPELRETIPAaiDLQIAQDRSPTI--RASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLC 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 390 GFSLNTLSLFGLVLAIGIVVDDAIVVVENVERNIEEGLAPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFY 469
Cdd:PRK10614 381 GFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLF 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 470 KQFAVTIAISTVISAINSLTLSPALAALLLKPHgAPKDFPTRlidrlfgwifRPFNRFFHRSSTGYQGLVGKTLGRRGAV 549
Cdd:PRK10614 461 REFAVTLSVAIGISLLVSLTLTPMMCAWLLKSS-KPREQKRL----------RGFGRMLVALQQGYGRSLKWVLNHTRWV 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 550 FVVYLLLLCAAGVMFKAVPGGFIPTQDKLYLIGGVKMPEGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGlnalqfTNT 629
Cdd:PRK10614 530 GVVLLGTIALNVWLYISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTG------GSR 603
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 630 PNTGTVFFGLKPFDQRKHSAAEINAEINAKIAQiQQGFGFSILPPPILGLG-----QGSGYSLYIQDRAglgygALQNAV 704
Cdd:PRK10614 604 VNSGMMFITLKPLSERSETAQQVIDRLRVKLAK-EPGANLFLMAVQDIRVGgrqsnASYQYTLLSDDLA-----ALREWE 677
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 705 NTMSGAIMQTPGMHFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADGPYR 784
Cdd:PRK10614 678 PKIRKALAALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYT 757
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 785 ESVEDIANLRTRNNQGEMVPIGSMVKISTTYGPDPViRYNGYPAADLIGDADPRVLSSAQAMTQLE-GMSKQILPNGMNI 863
Cdd:PRK10614 758 QDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSV-NHQGLSAASTISFNLPTGKSLSDASAAIErAMTQLGVPSTVRG 836
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 864 EW--TDLSFQQATqgNTALIVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLM 941
Cdd:PRK10614 837 SFagTAQVFQETM--NSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI 914
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 942 GLACKNAILIVEFARELEIQGK-GIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVT 1020
Cdd:PRK10614 915 GIVKKNAIMMVDFALEAQRNGNlTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQ 994
|
1050 1060
....*....|....*....|....*.
gi 1418658187 1021 LFGLFLTPVFYVTLRKFVTRGKEERE 1046
Cdd:PRK10614 995 LLTLYTTPVVYLFFDRLRLRFSRKPK 1020
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
12-1050 |
6.88e-78 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 277.03 E-value: 6.88e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 12 IFAAVLSILifitGLIAIPLLPVSEYPDVVPPSVQVRAEYPGANPKVIAETVATPLEEAINGVENMMYMKSVAgSDGVLV 91
Cdd:TIGR00914 18 LATLVMAIL----GIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLS-RYGLSQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 92 TTVTFRPGTDPDQAQVQVQNRVAQAEARLPEDVR-RLG-ITTQKQSPTLTLVVHLF----SPGGKYDSLYMRNYATLKVK 165
Cdd:TIGR00914 93 VTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSpEMGpISTGLGEIFLYTVEAEEgarkKDGGAYTLTDLRTIQDWIIR 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 166 DELARLPGVGQIQIFGSGEYAMRVWLDPNKVAARGLTASDVVTAMQEQNVQVSAGQL---GAEPLpkesdflisINAQGR 242
Cdd:TIGR00914 173 PQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIerrGEQYL---------VRAPGQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 243 LHTEEEFGNIILKTSQdGSLVRLRDVARIEMGSGSYALRSQLNNKDAVGIGIFQSPGANAIDLSNAVRAKMAELSTRFPE 322
Cdd:TIGR00914 244 VQSMDDIRNIVIATGE-GVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPE 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 323 DMKWAAPYDPTVFVRDSIRAVVQTLLEAVVLVVLVVILFLQTWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGlv 402
Cdd:TIGR00914 323 GVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGA-- 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 403 LAIGIVVDDAIVVVENVERNIEEGLAPLAA----------AHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQF 472
Cdd:TIGR00914 401 LDFGLIVDGAVVIVENAHRRLAEAQHHHGRqltlkerlheVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPM 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 473 AVTIAISTVISAINSLTLSPALAALLLKPHGAPKDfptrlidrlfgwifrpfNRFFHRSSTGYQGLVGKTLGRRGAVFVV 552
Cdd:TIGR00914 481 AFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKE-----------------NRLMRVLKRRYEPLLERVLAWPAVVLGA 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 553 YLLLLCAAGVMFKAVPGGFIPTQDKL-YLIGGVKMPeGSSLARTDAVIRKMSEIGMNTEGVDYAVAFPGLNALQFTNTP- 630
Cdd:TIGR00914 544 AAVSIVLVVWIASRVGGEFIPSLNEGdLAYQALRIP-GTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPp 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 631 NTGTVFFGLKPFDQ---RKHSAAEINAEINAKIAQIqQGFGFSILPPP-------ILGLGQGSGYSLYIQDRAGLGYGAL 700
Cdd:TIGR00914 623 NASDTYIILKPESQwpeGKKTKEDLIEEIQEATVRI-PGNNYEFTQPIqmrfnelISGVRSDVAVKVFGDDLDDLDATAE 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 701 QnavntMSGAIMQTPGMHFPISTYQANVPQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQAD 780
Cdd:TIGR00914 702 K-----ISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLP 776
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 781 GPYRESVEDIANL--RTRNNQGEM---VPIGSMVKISTTYGPDPVIRYNGYPAADLIGDADPRVLSS--AQAMTQLEGMS 853
Cdd:TIGR00914 777 ESLRESPQALRQLpiPLPLSEDARkqfIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSfvDDAKKAIAEQV 856
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 854 KqiLPNGMNIEWTDlSFQQATQGNTAL-IVFPVAVLLAFLVLAALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVF 932
Cdd:TIGR00914 857 K--LPPGYWITWGG-QFEQLQSATKRLqIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSIS 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 933 VQVGLVVLMGLACKNAILIVEFARELEIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITV 1012
Cdd:TIGR00914 934 AAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVV 1013
|
1050 1060 1070
....*....|....*....|....*....|....*...
gi 1418658187 1013 FSGMLGVTLFGLFLTPVFYVTLRKFVTRGKEEREVLPA 1050
Cdd:TIGR00914 1014 IGGIITATLLTLFVLPALYRLVHRRRHKGRKEHEPLEG 1051
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
729-1045 |
6.60e-09 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 60.00 E-value: 6.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 729 PQLDVQVDRDKAKAQGVSLTDLFGTLQTYLGSSYVNDFNQFGRTWRVMAQADgpyRESVEDIANLRTRNNQGEMVPIGSM 808
Cdd:pfam00873 182 YAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQ---LQSAEDFEKIIVKNQDGSPVRLRDV 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 809 VKI---STTYgpDPVIRYNGYPAADL----IGDADPRVLSSA--QAMTQLegmsKQILPNGMNIEWT--DLSFQQATQGN 877
Cdd:pfam00873 259 ATVelgSELY--RGFATFNGKPAVGLgvqkLPGANAIETADAvrAKLAEL----KPTFPQGVEIVVVydTTPFIRASIEE 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 878 T-----------ALIVFpvavllaflvlaALYESWTLPLAVILIVPMTMLSALFGVWLTGGDNNVFVQVGLVVLMGLACK 946
Cdd:pfam00873 333 VvktlleaivlvILVMF------------LFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVD 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 947 NAILIVE-FARELEIQGKGIMEAALEACRLRLRPIVMTSIAFIAGTIPLILGHGAGAEVRGVTGITVFSGMLGVTLFGLF 1025
Cdd:pfam00873 401 DAIVVVEnIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALT 480
|
330 340
....*....|....*....|
gi 1418658187 1026 LTPVFYVTLRKFVTRGKEER 1045
Cdd:pfam00873 481 LTPALCATLLKPRREPKHGG 500
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
905-1042 |
2.02e-07 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 55.25 E-value: 2.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 905 LAVILIVPMTM-LSALFGVW-LTGGDNNVFVQVGLVVLMGLACKNAILIVE-FARELEiQGKGIMEAALEACRLRLRPIV 981
Cdd:COG1033 631 LGLISLIPNLLpILLTFGLMgLLGIPLNIATAVVASIALGIGVDYTIHFLSrYREERR-KGGDLEEAIRRALRTTGKAIL 709
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1418658187 982 MTSIAFIAGTIPLILGHGAG-AEVRGVTGITVFSGMLGVtlfgLFLTPVFYVTLRKFVTRGK 1042
Cdd:COG1033 710 FTSLTLAAGFGVLLFSSFPPlADFGLLLALGLLVALLAA----LLLLPALLLLLDPRIAKKR 767
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
365-485 |
1.93e-04 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 45.62 E-value: 1.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 365 WRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLSLFGLVLAIGIVVDDAIVVVENVERNIEEGLAPLAAAHQAMREVSGPI 444
Cdd:COG1033 629 LRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAI 708
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1418658187 445 IAIALVLCAVFVPMAFlSGVTGQFYkqFAVTIAISTVISAI 485
Cdd:COG1033 709 LFTSLTLAAGFGVLLF-SSFPPLAD--FGLLLALGLLVALL 746
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
364-562 |
5.89e-04 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 44.08 E-value: 5.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 364 TWRASIIPLIAVPVSVVGTFSVLYLLGFSLNTLS--LFGLVLAIGivvddaivvvenV----------ERNIEEGLAPLA 431
Cdd:COG1033 241 SLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTilVPPLLLAIG------------IdygihllnryREERRKGLDKRE 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418658187 432 AAHQAMREVSGPIIaIALVLCAVfvpmAFLSGVTGQF--YKQFAVTIAISTVISAINSLTLS-PALAALLLKPHGAPKDF 508
Cdd:COG1033 309 ALREALRKLGPPVL-LTSLTTAI----GFLSLLFSDIppIRDFGIVAAIGVLLAFLTSLTLLpALLSLLPRPKPKTRRLK 383
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1418658187 509 PTRLIDRLFGWIFRpfnrffhrsstgyqglvgKTLGRRGAVFVVYLLLLCAAGV 562
Cdd:COG1033 384 KPPELGRLLAKLAR------------------FVLRRPKVILVVALVLAVVSLY 419
|
|
| |
