|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10764 |
PRK10764 |
potassium-tellurite ethidium and proflavin transporter; Provisional |
7-328 |
5.98e-170 |
|
potassium-tellurite ethidium and proflavin transporter; Provisional
Pssm-ID: 236756 Cd Length: 324 Bit Score: 475.21 E-value: 5.98e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 7 PQKVLNLPAGYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSF 86
Cdd:PRK10764 3 SDKVLPLPAGYFGIVLGLIGLGFAWRYAAQLWPLPAWIGEALVALASIIWALLILAYLYKWIRFPESVLAELRHPVQSSF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 87 VSLFPATTMLVAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGNHPQEATTPGLYLPTVANNFISAMACGALGFN 166
Cdd:PRK10764 83 VSLIPITTMLVAIGLVPYSRPLAVVLFSFGVVGQLAFAAWRTAGLWRGGHPEEATTPGLYLPTVANNFVSAMALGALGYH 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 167 DAGFVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGGEADTFAKMLFGYGLLQLLFML 246
Cdd:PRK10764 163 DAGLLFLGAGVFSWLSLEPVILQRLRSSGELPTALRPSLGIQLAPAFVGCSAYLSVNGGEGDTLAKMLFGYGLLQLLFLL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 247 RLLPWYISQPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRTFILLLQGKLLLRTEKAL 326
Cdd:PRK10764 243 RLMPWILSQGFNASFWSFSFGVAALATTGLHLGHGSDNGFFHTLAVPLFIFANFIIALLLLRTLALLMQGKLLVRTERAV 322
|
..
gi 1418703594 327 LM 328
Cdd:PRK10764 323 LM 324
|
|
| TDT_TehA |
cd09324 |
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; This ... |
14-310 |
6.13e-132 |
|
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; This subfamily includes Tellurite resistance protein TehA that belongs to the C4-dicarboxylate transporter/malic acid transport (TDT) protein family and is a homolog of plant Slow Anion Channel-Associated 1 (SLAC1). The tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.
Pssm-ID: 187764 Cd Length: 301 Bit Score: 377.76 E-value: 6.13e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 14 PAGYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSFVSLFPAT 93
Cdd:cd09324 1 PVGYFGIVLGLAALGLAWRYAAQLWPLPAIVGESLLALASVVWLLLIGAYAYKWLKYREEARAELRHPVQCCFISLIPIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 94 TMLVAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGNHPQEATTPGLYLPTVANNFISAMACGALGFNDAGFVFL 173
Cdd:cd09324 81 TMLVGIALYPYSRLLAEVLIVLGIIGQLAFAAWRTGGLWQGGHFPEATTPVLYLPTVAGNFVSASALAALGYHDLGMLFF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 174 GAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGGEADTFAKMLFGYGLLQLLFMLRLLPWYI 253
Cdd:cd09324 161 GAGMFSWLSLEPVILQRLRTSPPLPPALRPTLGIQLAPAFVGCSAYLSLNGGEVDLLAKMLWGYGLLQLLFLLRLLPWIA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1418703594 254 SQPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRTF 310
Cdd:cd09324 241 EQGFSMGFWAFSFGLAAMATSGLHLYHGGVLGPLSLLALALFNVANGLIALLTLGTL 297
|
|
| tdt |
TIGR00816 |
C4-dicarboxylate transporter/malic acid transport protein; The Tellurite-Resistance ... |
13-310 |
5.41e-85 |
|
C4-dicarboxylate transporter/malic acid transport protein; The Tellurite-Resistance/Dicarboxylate Transporter (TDT) Family (TC 2.A.16)Two members of the TDT family have been functionally characterized. One is the TehA protein of E. coli which has been implicated in resistance to tellurite; the other is the Mae1 protein of S. pombe which functions in the uptake of malate and other dicarboxylates by a proton symportmechanism. These proteins exhibit 10 putative transmembrane a-helicalspanners (TMSs). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273285 Cd Length: 320 Bit Score: 259.26 E-value: 5.41e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 13 LPAGYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSFVSLFPA 92
Cdd:TIGR00816 1 FPWGWFAIVLGTGGLALASLSYSFYLPILKDLSDVLFILAIALFFLFTSCWLARLIRYPSNVLAELKHPVLSSFIPLIPI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 93 TTMLVAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGN-HPQEATTPGLYLPTVANNFISAMACGALGFNDAG-- 169
Cdd:TIGR00816 81 STMLLGIDFIIWGYPLALGLWYIGAIGQLLFSVIVPFYLFKNEsIEIEHTHPGWYLPPVALIFISAAALAILPYLTHElt 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 170 ---FVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFS-VNGGEADT-------FAKMLFGYG 238
Cdd:TIGR00816 161 vlfYFGWGAGFFLYLSLEAVLLLRLRLHGLLPSALRPTMFINLAPIGVGIVALINiVNHGEFITikepfliLAIILWGFG 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1418703594 239 LLQLLFMLRLLPWYISQ--PFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRTF 310
Cdd:TIGR00816 241 LWQLLFAIRLLLWYVKLklPFAMGWWAFIFPLAAYANSTHLVYKGFDFKVFQYIGFGLYVFLNFFWAILLIRTV 314
|
|
| TehA |
COG1275 |
Tellurite resistance protein TehA and related permeases [Defense mechanisms]; |
5-311 |
2.42e-81 |
|
Tellurite resistance protein TehA and related permeases [Defense mechanisms];
Pssm-ID: 440886 Cd Length: 323 Bit Score: 249.77 E-value: 2.42e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 5 NPPQKVLNLPAGYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMS 84
Cdd:COG1275 4 APRSRLRNLPPAWFALVMGTGGLGLAWRLAAALLPGPAAIAEVLLALAALLFLVLLLLYLLKWLRYPAAVRADLRHPVRG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 85 SFVSLFPATTMLVAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGNHPQ-EATTPGLYLPTVANNFISAMACGAL 163
Cdd:COG1275 84 SFFPTIPMALLLLGTGLLPLAPALALVLWLLGVALHLALTVYFPYRLFTGEKFEiEHITPAWFIPVVGNIVVAVAGALLG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 164 GFNDAGFVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGGEADTFAKMLFGYGLLQLL 243
Cdd:COG1275 164 PLLELSYAFFGVGLFLYLVLLPLVLYRLIFHKPLPEALRPTLWILLAPPAVGLLAYLALGGGPLDGFALILWGFGLWWLL 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1418703594 244 FMLRLLPWYISQPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRTFI 311
Cdd:COG1275 244 LLLLLTPRLLRLPFSPSWWAFTFPLAAYATATLRLAEATGLPFLAVLALALLVLATLVWLYVLVRTLR 311
|
|
| SLAC1 |
pfam03595 |
Voltage-dependent anion channel; This family of transporters has ten alpha helical ... |
12-301 |
1.38e-33 |
|
Voltage-dependent anion channel; This family of transporters has ten alpha helical transmembrane segments. The structure of a bacterial homolog of SLAC1 shows it to have a trimeric arrangement. The pore is composed of five helices with a conserved Phe residue involved in gating. One homolog, Mae1 from the yeast Schizosaccharomyces pombe, functions as a malate uptake transporter; another, Ssu1 from Saccharomyces cerevisiae and other fungi including Aspergillus fumigatus, is characterized as a sulfite efflux pump; and TehA from Escherichia coli is identified as a tellurite resistance protein by virtue of its association in the tehA/tehB operon. In plants, this family is found in the stomatal guard cells functioning as an anion-transporting pore. Many homologs are incorrectly annotated as tellurite resistance or dicarboxylate transporter (TDT) proteins.
Pssm-ID: 460983 Cd Length: 321 Bit Score: 125.81 E-value: 1.38e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 12 NLPAGYFGMVLGIIGMGFAWRYAStLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSFVSLFP 91
Cdd:pfam03595 1 HFTPAWFAIVMGTGGLALLLHHLP-YGRGLRTIGLILFILNLVLFLLLLLLYLLRFILYPEAVRAELRHPVESLFLGTFP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 92 ATTMLVAIGFV------PWCRPISVVLFG-VGVVTQLSYSAWQSAGLWRGNHPQEATTPGLYLPTVANNFISAMA----C 160
Cdd:pfam03595 80 MGFATIINGLVlvpvpgPWLVTLAWVLWWwIGVALALAFAVGVPFLLFTRHHLLEAMTPAWLLPVVPLMVVAALGallaA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 161 GALGFNDAGFVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGGEADTFAKMLFGYGLL 240
Cdd:pfam03595 160 LLLPILVVSYLLWGLGLFLALVILAIYLYRLFTHGLPPAELRPSLFIPLGPPGQGALALLLLGGAAPTILPALTALAGEI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 241 QLLFMLRLLPWYIS---------------------QPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTN 299
Cdd:pfam03595 240 LYVVALLLALFLWGfglwwffiaalsvlsalrrggLPFNLGWWAFTFPLGAFALATIELGKALDSPFFRVLGTILSVLLV 319
|
..
gi 1418703594 300 VI 301
Cdd:pfam03595 320 LV 321
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10764 |
PRK10764 |
potassium-tellurite ethidium and proflavin transporter; Provisional |
7-328 |
5.98e-170 |
|
potassium-tellurite ethidium and proflavin transporter; Provisional
Pssm-ID: 236756 Cd Length: 324 Bit Score: 475.21 E-value: 5.98e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 7 PQKVLNLPAGYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSF 86
Cdd:PRK10764 3 SDKVLPLPAGYFGIVLGLIGLGFAWRYAAQLWPLPAWIGEALVALASIIWALLILAYLYKWIRFPESVLAELRHPVQSSF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 87 VSLFPATTMLVAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGNHPQEATTPGLYLPTVANNFISAMACGALGFN 166
Cdd:PRK10764 83 VSLIPITTMLVAIGLVPYSRPLAVVLFSFGVVGQLAFAAWRTAGLWRGGHPEEATTPGLYLPTVANNFVSAMALGALGYH 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 167 DAGFVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGGEADTFAKMLFGYGLLQLLFML 246
Cdd:PRK10764 163 DAGLLFLGAGVFSWLSLEPVILQRLRSSGELPTALRPSLGIQLAPAFVGCSAYLSVNGGEGDTLAKMLFGYGLLQLLFLL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 247 RLLPWYISQPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRTFILLLQGKLLLRTEKAL 326
Cdd:PRK10764 243 RLMPWILSQGFNASFWSFSFGVAALATTGLHLGHGSDNGFFHTLAVPLFIFANFIIALLLLRTLALLMQGKLLVRTERAV 322
|
..
gi 1418703594 327 LM 328
Cdd:PRK10764 323 LM 324
|
|
| TDT_TehA |
cd09324 |
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; This ... |
14-310 |
6.13e-132 |
|
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; This subfamily includes Tellurite resistance protein TehA that belongs to the C4-dicarboxylate transporter/malic acid transport (TDT) protein family and is a homolog of plant Slow Anion Channel-Associated 1 (SLAC1). The tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.
Pssm-ID: 187764 Cd Length: 301 Bit Score: 377.76 E-value: 6.13e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 14 PAGYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSFVSLFPAT 93
Cdd:cd09324 1 PVGYFGIVLGLAALGLAWRYAAQLWPLPAIVGESLLALASVVWLLLIGAYAYKWLKYREEARAELRHPVQCCFISLIPIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 94 TMLVAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGNHPQEATTPGLYLPTVANNFISAMACGALGFNDAGFVFL 173
Cdd:cd09324 81 TMLVGIALYPYSRLLAEVLIVLGIIGQLAFAAWRTGGLWQGGHFPEATTPVLYLPTVAGNFVSASALAALGYHDLGMLFF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 174 GAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGGEADTFAKMLFGYGLLQLLFMLRLLPWYI 253
Cdd:cd09324 161 GAGMFSWLSLEPVILQRLRTSPPLPPALRPTLGIQLAPAFVGCSAYLSLNGGEVDLLAKMLWGYGLLQLLFLLRLLPWIA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1418703594 254 SQPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRTF 310
Cdd:cd09324 241 EQGFSMGFWAFSFGLAAMATSGLHLYHGGVLGPLSLLALALFNVANGLIALLTLGTL 297
|
|
| tdt |
TIGR00816 |
C4-dicarboxylate transporter/malic acid transport protein; The Tellurite-Resistance ... |
13-310 |
5.41e-85 |
|
C4-dicarboxylate transporter/malic acid transport protein; The Tellurite-Resistance/Dicarboxylate Transporter (TDT) Family (TC 2.A.16)Two members of the TDT family have been functionally characterized. One is the TehA protein of E. coli which has been implicated in resistance to tellurite; the other is the Mae1 protein of S. pombe which functions in the uptake of malate and other dicarboxylates by a proton symportmechanism. These proteins exhibit 10 putative transmembrane a-helicalspanners (TMSs). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273285 Cd Length: 320 Bit Score: 259.26 E-value: 5.41e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 13 LPAGYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSFVSLFPA 92
Cdd:TIGR00816 1 FPWGWFAIVLGTGGLALASLSYSFYLPILKDLSDVLFILAIALFFLFTSCWLARLIRYPSNVLAELKHPVLSSFIPLIPI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 93 TTMLVAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGN-HPQEATTPGLYLPTVANNFISAMACGALGFNDAG-- 169
Cdd:TIGR00816 81 STMLLGIDFIIWGYPLALGLWYIGAIGQLLFSVIVPFYLFKNEsIEIEHTHPGWYLPPVALIFISAAALAILPYLTHElt 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 170 ---FVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFS-VNGGEADT-------FAKMLFGYG 238
Cdd:TIGR00816 161 vlfYFGWGAGFFLYLSLEAVLLLRLRLHGLLPSALRPTMFINLAPIGVGIVALINiVNHGEFITikepfliLAIILWGFG 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1418703594 239 LLQLLFMLRLLPWYISQ--PFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRTF 310
Cdd:TIGR00816 241 LWQLLFAIRLLLWYVKLklPFAMGWWAFIFPLAAYANSTHLVYKGFDFKVFQYIGFGLYVFLNFFWAILLIRTV 314
|
|
| TehA |
COG1275 |
Tellurite resistance protein TehA and related permeases [Defense mechanisms]; |
5-311 |
2.42e-81 |
|
Tellurite resistance protein TehA and related permeases [Defense mechanisms];
Pssm-ID: 440886 Cd Length: 323 Bit Score: 249.77 E-value: 2.42e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 5 NPPQKVLNLPAGYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMS 84
Cdd:COG1275 4 APRSRLRNLPPAWFALVMGTGGLGLAWRLAAALLPGPAAIAEVLLALAALLFLVLLLLYLLKWLRYPAAVRADLRHPVRG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 85 SFVSLFPATTMLVAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGNHPQ-EATTPGLYLPTVANNFISAMACGAL 163
Cdd:COG1275 84 SFFPTIPMALLLLGTGLLPLAPALALVLWLLGVALHLALTVYFPYRLFTGEKFEiEHITPAWFIPVVGNIVVAVAGALLG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 164 GFNDAGFVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGGEADTFAKMLFGYGLLQLL 243
Cdd:COG1275 164 PLLELSYAFFGVGLFLYLVLLPLVLYRLIFHKPLPEALRPTLWILLAPPAVGLLAYLALGGGPLDGFALILWGFGLWWLL 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1418703594 244 FMLRLLPWYISQPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRTFI 311
Cdd:COG1275 244 LLLLLTPRLLRLPFSPSWWAFTFPLAAYATATLRLAEATGLPFLAVLALALLVLATLVWLYVLVRTLR 311
|
|
| TDT_TehA_like |
cd09322 |
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA proteins; The ... |
17-306 |
7.33e-73 |
|
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA proteins; The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane a-helical spanners (TMSs).
Pssm-ID: 187762 Cd Length: 289 Bit Score: 227.04 E-value: 7.33e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 17 YFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSFVSLFPATTML 96
Cdd:cd09322 1 LFPIVLGLLGLGLAWLGALLLLGLPSIVGEILGILALLLWLLLLLKYLLKLLRYPEAVKAELRHPVRASFFATFSMSLML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 97 VAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGNHPQEATTPGLYLPTVANNFISAMACgALGFNDAGFVFLGAG 176
Cdd:cd09322 81 LSIYLLPYSPLLARVLWILGAVLHLVFTLYFVSRWIRGGKFLEHVTPSWFIPYVGNIVVPVTGP-ALGGPELGWFFFGVG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 177 VFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGGEADTFAKMLFGYGLLQLLFMLRLLPWYISQP 256
Cdd:cd09322 160 LIFWLVLLPLVLYRLIFHEPLPEPLRPTLAILLAPPSLGLAAYLALFGGPIDLFALILLGLALFLFLLLLRLLPRLLKLP 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1418703594 257 FNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILL 306
Cdd:cd09322 240 FSPSWWAFTFPLAALAIALLKMAAYLGSGFLQLLALVLLELLTAVILVLY 289
|
|
| TDT_SLAC1_like |
cd09323 |
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes SLAC1 (Slow Anion ... |
12-309 |
1.26e-49 |
|
Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes SLAC1 (Slow Anion Channel-Associated 1); SLAC1 (Slow Anion Channel-Associated 1) is a plasma membrane protein, preferentially expressed in guard cells, which encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. It is essential for stomatal closure in response to carbon dioxide, abscisic acid, ozone, light/dark transitions, humidity change, calcium ions, hydrogen peroxide and nitric oxide. In the Arabidopsis genome, SLAC1 is part of a gene family with five members and encodes a membrane protein that has ten putative transmembrane domains flanked by large N- and C-terminal domains. Mutations in SLAC1 impair slow (S-type) anion channel currents that are activated by cytosolic calcium ions and abscisic acid, but do not affect rapid (R-type) anion channel currents or calcium ion channel function.
Pssm-ID: 187763 Cd Length: 297 Bit Score: 167.34 E-value: 1.26e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 12 NLPAGYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSFVSLFP 91
Cdd:cd09323 1 HFPVSLFAIVMGLSGLALAWRKAAELLGLPAAISEALGWLAVAVFVVLAALYALKILRYPEAVKAEFNHPVRINFFPAIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 92 ATTMLVAIGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGNHPQEAT-TPGLYLPTVAnNFISAMACGALGFNDAGF 170
Cdd:cd09323 81 ISLLLLSIALLPYSPVLALALWIIGAVLQLALTLYVVSRWISHRQFQIGHaNPAWFIPVVG-NLVVPIAGVPLGYAEVSW 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 171 VFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNgGEADTFAKMLFGYGLLQLLFMLRLLP 250
Cdd:cd09323 160 FFFSVGLFFWLVLFTIVFNRLIFHEPLPAKLLPTLFILIAPPAVGFLAYLKLT-GSLDAFARILYYIALFLFLLLLFQVR 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1418703594 251 WYISQPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRT 309
Cdd:cd09323 239 RFRKLPFFLSWWAYSFPLAALAIATLRMAELTGSLFLQVLALVLLALLTLVVAVLLVRT 297
|
|
| SLAC1 |
pfam03595 |
Voltage-dependent anion channel; This family of transporters has ten alpha helical ... |
12-301 |
1.38e-33 |
|
Voltage-dependent anion channel; This family of transporters has ten alpha helical transmembrane segments. The structure of a bacterial homolog of SLAC1 shows it to have a trimeric arrangement. The pore is composed of five helices with a conserved Phe residue involved in gating. One homolog, Mae1 from the yeast Schizosaccharomyces pombe, functions as a malate uptake transporter; another, Ssu1 from Saccharomyces cerevisiae and other fungi including Aspergillus fumigatus, is characterized as a sulfite efflux pump; and TehA from Escherichia coli is identified as a tellurite resistance protein by virtue of its association in the tehA/tehB operon. In plants, this family is found in the stomatal guard cells functioning as an anion-transporting pore. Many homologs are incorrectly annotated as tellurite resistance or dicarboxylate transporter (TDT) proteins.
Pssm-ID: 460983 Cd Length: 321 Bit Score: 125.81 E-value: 1.38e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 12 NLPAGYFGMVLGIIGMGFAWRYAStLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSFVSLFP 91
Cdd:pfam03595 1 HFTPAWFAIVMGTGGLALLLHHLP-YGRGLRTIGLILFILNLVLFLLLLLLYLLRFILYPEAVRAELRHPVESLFLGTFP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 92 ATTMLVAIGFV------PWCRPISVVLFG-VGVVTQLSYSAWQSAGLWRGNHPQEATTPGLYLPTVANNFISAMA----C 160
Cdd:pfam03595 80 MGFATIINGLVlvpvpgPWLVTLAWVLWWwIGVALALAFAVGVPFLLFTRHHLLEAMTPAWLLPVVPLMVVAALGallaA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 161 GALGFNDAGFVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGGEADTFAKMLFGYGLL 240
Cdd:pfam03595 160 LLLPILVVSYLLWGLGLFLALVILAIYLYRLFTHGLPPAELRPSLFIPLGPPGQGALALLLLGGAAPTILPALTALAGEI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 241 QLLFMLRLLPWYIS---------------------QPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTN 299
Cdd:pfam03595 240 LYVVALLLALFLWGfglwwffiaalsvlsalrrggLPFNLGWWAFTFPLGAFALATIELGKALDSPFFRVLGTILSVLLV 319
|
..
gi 1418703594 300 VI 301
Cdd:pfam03595 320 LV 321
|
|
| TDT |
cd09299 |
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance ... |
17-309 |
2.20e-16 |
|
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane alpha-helical spanners (TMSs).
Pssm-ID: 187756 Cd Length: 326 Bit Score: 78.52 E-value: 2.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 17 YFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRH-PVMSSFVSLFPATTM 95
Cdd:cd09299 1 WFGIVMGTGILSLALYLLPYQFPGLRIIGKILFILAIVIFILFFALWLLRLIRYPRHVVRESHHnPVEASFLAAVPISLF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 96 LVAIGFVPWCRP--------ISVVLFGVGVVTQLSYSAWQSAGLWRGNHP-QEATTPGLYLPTVANNFISAMA------- 159
Cdd:cd09299 81 TIIDFLALYGGAntgrlvilIAYVLWWIGLALSLVSAVGVPYLLFTNHVYeIEHISPAWLLPIVPPMTSAALAgallpys 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 160 ---CGALGFNDAGFVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFSVNGG----------- 225
Cdd:cd09299 161 pggAIQLSVIFLGYLFFGIGFFLFIFIGAIIFSRLVINKLPPGQLAPTLMIVLGPMGQSIFALLLLGKNarlifflyasf 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 226 ---EADTFAKMLFGYGLLQLLFMLRLLPWYI--SQPFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAvplFIFTNV 300
Cdd:cd09299 241 lqaLAVFASIILWGFGLWWLLLALVSILRTLrkKLPFSLGWWSYVFPLGVYTNGTYALYKLMDLPAFSIFA---TILLII 317
|
....*....
gi 1418703594 301 IIGILLVRT 309
Cdd:cd09299 318 LVALWILCT 326
|
|
| TDT_like_3 |
cd09321 |
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance ... |
16-310 |
2.30e-15 |
|
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane a-helical spanners (TMSs).
Pssm-ID: 187761 Cd Length: 327 Bit Score: 75.80 E-value: 2.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 16 GYFGMVLGIIGMGFAWRYASTLWPVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRSVLAEMRHPVMSSFVSLFPATTM 95
Cdd:cd09321 4 SWFASVMGTGALAIASYLYSAYFPFLKTLAVFLTYLNFLLFFVLLVPWLLRWILYPKEALADLKHPVLSNFYPTMPIALL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 96 LVA-----IGFVPWCRPISVVLFGVGVVTQLSYSAWQSAGLWRGNH-PQEATTPGLYLPTVAN-------NFISAMACGA 162
Cdd:cd09321 84 VLAtniliVGQGPLGYSLALTLWILGSILIFIFSFIVSYIMFINEEiPIEHINPAWFIPPVGLiviplagNFLIPHFPGA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 163 LG--FNDAGFVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPALVACSAWFS-VNGGEADT---------- 229
Cdd:cd09321 164 WQesILVINLFGFGIGFFLFLFLLAIILHRLILHEPPPPELAPTFWINLAPIGAGVVALINlVKALPFAGlenlvdlani 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 230 FAKMLFGYGLLQLLFMLRLLPWYISQ---PFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILL 306
Cdd:cd09321 244 FALILWGFGLWWLILAVLLTLYYLKRgnlPFSLGWWAFIFPLGAYTIATYLVAKVLNFSFLSGLGIFLYWLLLILWAITL 323
|
....
gi 1418703594 307 VRTF 310
Cdd:cd09321 324 FKTL 327
|
|
| TDT_C4-dicarb_trans |
cd09325 |
C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) ... |
12-308 |
2.54e-08 |
|
C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.
Pssm-ID: 187765 Cd Length: 293 Bit Score: 54.48 E-value: 2.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 12 NLPAGYFGMVLGIIGMGfaWRYASTLWPVTRWPGDALvalAVTCWFLLTVAFIIrairFPRSVLAEMRHPVMSSFVSLFP 91
Cdd:cd09325 1 KIPIPIAGLALGLASLG--NLLELSYGSILRNICGLI---ALILLILLLLKIIL----FPKTLKEELKNPVIASVFPTFP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 92 ATTMLVAIGFVPWCRPISVVLFGVGVV---TQLSYSAWQSAGLWRGNHPqeatTPGLYLPTVANnFISAMACGALGFNDA 168
Cdd:cd09325 72 MALMLLSTYLKPFFPALAQLLWLLAIIlhiILIIYFTYKRILKFNLEHV----FPSWFVVYVGI-VVASVTAPAFGQPLL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 169 GFVFLGAGVFSWLSLEPVILQRLRSAGELPTAQRTSLGIQLAPAlVACSAWFSVNGGEADT-FAKMLFGYGLLQLLFMLR 247
Cdd:cd09325 147 GQIAFWFGFVAYLILLPLVLYRLVKIKELPDAALPTIAIFAAPA-SLCLAGYLNSFPEPNPvLVLFLLILSQLLYFFVLL 225
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1418703594 248 LLPWYISQPFNASFWSFSF--GISALA---TTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVR 308
Cdd:cd09325 226 QLPRLLKLPFYPSFAAFTFplVISATAlkkTSTYLASYGLYLPILKYLALFEILIATVIVLYVLIR 291
|
|
| TDT_like_2 |
cd09320 |
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance ... |
39-309 |
2.35e-03 |
|
The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane alpha-helical spanners (TMSs).
Pssm-ID: 187760 Cd Length: 327 Bit Score: 39.23 E-value: 2.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 39 PVTRWPGDALVALAVTCWFLLTVAFIIRAIRFPRsvLAEMRHPVMSSFVSLFP---------ATTMLVAIGFVPWCRPIS 109
Cdd:cd09320 25 PGLRTGAEAFWLVAALLLVALTAGFAAHWRRHPA--FARARDPVMMPFWGMVSmgllavgaaTLTVGPDVIGHDAAVAVD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 110 VVLFGVGVVTQLSYSAWQSAGLWRgnHPQEATTPGLYLP--------TVANNFISAMACGALGFN--DAGFVFLGAGVFS 179
Cdd:cd09320 103 TVLWVIGTVLGLVTAVVIPRRLIR--RHRGTPTPVWGLPvvppmvsaTTGAQLVPHLPAGQPRLTllLACYACFGLSLLA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418703594 180 WLSLEPVILQRLRSAGELPTAQRTSLGIQL--------APALVACSAWFSVNGGEADTFAKMLFGYGLLQLLFMLRLLPW 251
Cdd:cd09320 181 AAIIFALVYRRLWRGGPLPLAAAPTAWIPLgvvgqstaAAQLLAAAAGHVLPPPTAQTLHVFAVLYGVVMLGFGVPLLAL 260
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1418703594 252 YISQ---------PFNASFWSFSFGISALATTGLHLGHSSPSGFFHVIAVPLFIFTNVIIGILLVRT 309
Cdd:cd09320 261 AAAVtvravrrgmPFSPTWWAFTFPVGTCVLGAHALAVHTGLAWFDWLAAALLVLLLAHWTVCAART 327
|
|
| |
