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Conserved domains on  [gi|1425613064|gb|RBU29884|]
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TonB-dependent siderophore receptor [Escherichia coli]

Protein Classification

TonB-dependent siderophore receptor( domain architecture ID 11486670)

TonB-dependent siderophore receptor acts as a channel to allow import of iron-siderophore complexes, such as Escherichia coli ferrienterobactin receptor, which is involved in the initial step of iron uptake by binding ferrienterobactin

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-746 0e+00

FepA family TonB-dependent siderophore receptor;


:

Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 1465.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   1 MNKKIHSLALLVNLGIYGVAQAQEPT-----DTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSEIIRTMP 75
Cdd:PRK13524    1 MNKKIHSLALLVNLGIYGVAQAAEAEdaktdDTPASHEDTIVVTAAEQNLQAPGVSTITAEDIRKRPPANDVSEIIRTMP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  76 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARY 155
Cdd:PRK13524   81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGPAAARY 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 156 GNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQADAWDINQGHQSAR 235
Cdd:PRK13524  161 GNGAAGGVVNIITKKPTGEWHGSWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQADAWDINQGHQSAR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 236 AGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYSLTW 315
Cdd:PRK13524  241 TGSYAGTLPAGREGVINKDINGLLRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDALVKSLYGKETNRMYRQNYALTH 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 316 NGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQdFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQR 395
Cdd:PRK13524  321 RGGWDNGVSTSNYAQYEHTRNSRLPEGLAGGTEGIFNEKATQ-FSTIDLDDVMLHSEVNLPFDLLVNQTLTLGTEWNQQR 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 396 MKDLSSNTQALTgtnTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLG 475
Cdd:PRK13524  400 MKDPSSNTQALT---SGGAIPGVSATGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLG 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 476 DDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASA-GGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDY 554
Cdd:PRK13524  477 DDFTLKMGIARAYKAPNLYQTNPNYILYSKGQGCYASAgNGCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDY 556
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 555 RNKIEAGYVAVGQNAVG-TDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTL 633
Cdd:PRK13524  557 RNKIEAGYVPVGTNSVGkTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLNSTL 636
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 634 SWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQT 713
Cdd:PRK13524  637 SWQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWREGNAQT 716
                         730       740       750
                  ....*....|....*....|....*....|...
gi 1425613064 714 TGdlagaNYIAGAGAYTYNEPGRTWYMSINTHF 746
Cdd:PRK13524  717 TG-----DLIAGAGAYTYNEPGRTYYMSLNTHF 744
 
Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-746 0e+00

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 1465.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   1 MNKKIHSLALLVNLGIYGVAQAQEPT-----DTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSEIIRTMP 75
Cdd:PRK13524    1 MNKKIHSLALLVNLGIYGVAQAAEAEdaktdDTPASHEDTIVVTAAEQNLQAPGVSTITAEDIRKRPPANDVSEIIRTMP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  76 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARY 155
Cdd:PRK13524   81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGPAAARY 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 156 GNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQADAWDINQGHQSAR 235
Cdd:PRK13524  161 GNGAAGGVVNIITKKPTGEWHGSWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQADAWDINQGHQSAR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 236 AGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYSLTW 315
Cdd:PRK13524  241 TGSYAGTLPAGREGVINKDINGLLRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDALVKSLYGKETNRMYRQNYALTH 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 316 NGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQdFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQR 395
Cdd:PRK13524  321 RGGWDNGVSTSNYAQYEHTRNSRLPEGLAGGTEGIFNEKATQ-FSTIDLDDVMLHSEVNLPFDLLVNQTLTLGTEWNQQR 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 396 MKDLSSNTQALTgtnTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLG 475
Cdd:PRK13524  400 MKDPSSNTQALT---SGGAIPGVSATGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLG 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 476 DDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASA-GGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDY 554
Cdd:PRK13524  477 DDFTLKMGIARAYKAPNLYQTNPNYILYSKGQGCYASAgNGCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDY 556
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 555 RNKIEAGYVAVGQNAVG-TDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTL 633
Cdd:PRK13524  557 RNKIEAGYVPVGTNSVGkTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLNSTL 636
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 634 SWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQT 713
Cdd:PRK13524  637 SWQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWREGNAQT 716
                         730       740       750
                  ....*....|....*....|....*....|...
gi 1425613064 714 TGdlagaNYIAGAGAYTYNEPGRTWYMSINTHF 746
Cdd:PRK13524  717 TG-----DLIAGAGAYTYNEPGRTYYMSLNTHF 744
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
50-746 1.58e-145

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 440.70  E-value: 1.58e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  50 VSTITADEIRKNPvARDVSEIIRTMPGVNLTGNSTSGQRGNnrqIDIRGMGPEntlILIDGkpvSSRNSVRQGWRGerdt 129
Cdd:TIGR01783   6 VSVITRQELEDQQ-AGSLSEALQRVPGVVVGGSGGTTQFGN---ITIRGFGLE---VDIDN---VYLDGVPLLSRG---- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 130 rgDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEwhgswdAYFNAPEHKEEGATKRTNFSLTGPLGDEF 209
Cdd:TIGR01783  72 --NLAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDE------PKGSVTFGAGTRSGYRTAFDLGGPLGADG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 210 SFRLYGNLDKTQADAWDINQGHQSaRAGTYATTLPAgrEGVINKDINGVVRWDFAPLQSLELEA-----GYSRQGNLYAG 284
Cdd:TIGR01783 144 TFRGRLNGARQDGDSFYDGAGEET-RLGATATDWQL--DDRTLLRLGAYYQKERDRGGYGGLPAsggtsGRDLSSDRYLG 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 285 DTQNTNSDSYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHTRNSripEGLAGGTEGKFNEKatQDFVDIDL 364
Cdd:TIGR01783 221 TSSNRNYDDREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSD---GGLFGRSLTVVNVK--QDRVQIDA 295
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 365 DDVMLHSEVNLPIDFLVNQ-TLTLGTEWNQQrMKDLSSNTQALTGTNTGGAIDGVSATDRSPYSKAEIFSLFAENNMELT 443
Cdd:TIGR01783 296 GLDGEFETGPIEHDLLLGVsYGQRTTNRFNN-TGYPSDNIYSLTATSSARTDIGDSPKDRALSSTTKALNGVALQRILLA 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 444 DSTIVTPGLRFDHHSIVGNNwspALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYAsagGCYLQGNDD 523
Cdd:TIGR01783 375 DKWTLTLGGRYDSVDVKSNN---GVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYP---KGAGNSGDI 448
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 524 LKAETSINKEIGLEFKR-DGWLAGVTWFRNDYRNKIEAGyVAVGQNAVGTDLYQWDNVPKAVVEGLegSLNVPVSETVMW 602
Cdd:TIGR01783 449 LEPEKGKNYELGVRYDLgDSLLATAALFRITKDNQLVQD-PVNGTFSVNAGKTRNRGVELEARGYL--TPGLSLSAGYTY 525
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 603 TNNITYMLKSENkTTGDRLSIIPEYTLNSTLSWQAREDlSMQTTFTWYGKQQPKKYnykgqpAVGPETKEISPYSIVGLS 682
Cdd:TIGR01783 526 TDAEFTEDTNGD-TQGNTVPFVPKHTASLWASYAPPVG-DNGLTLGGGVQYTGKAY------VDGGNTGKVPSYTVVDLS 597
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1425613064 683 ATWDVT--KNVSLTGGVDNLFDKRLWRAGNAQTTgdlaganyiagaGAYTYNEPGRTWYMSINTHF 746
Cdd:TIGR01783 598 VRYDLTkkKNLTLALNVNNLFDRDYYTSGYRWGP------------SAYIYPGAPRTVGLSVSYDF 651
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
49-746 3.49e-136

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 416.08  E-value: 3.49e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  49 GVSTITADEIRKNPvARDVSEIIRTMPGVNLTGNStsgqRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGwrgerd 128
Cdd:cd01347     1 SVSVITAEDIEKQP-ATSLADLLRRIPGVSVTRGG----GGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGV------ 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 129 trgDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPehkEEGATKRTNFSLTGPLGDE 208
Cdd:cd01347    70 ---DLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSD---NSGSSGGGGFDVSGALADD 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 209 --FSFRLYGNLDKTQADAWDInqghqsaragtyattLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDT 286
Cdd:cd01347   144 gaFGARLYGAYRDGDGTIDGD---------------GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGT 208
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 287 QNTNS---------DSYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNW-VQYEHTRNSRIPEGLAGGTEGKFNEKA- 355
Cdd:cd01347   209 LPANGtgsslgggpSSNTNGDRDWDYRDRYRKRASLGLEHDLNDTGWTLRAnLSYSYTDNDGDPLILNGGNNAAGGDLGr 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 356 TQDFVDIDLDDVMLHSEVNLPID-FLVNQTLTLGTEWNQQRmkdlssntqaltgtntggaidgvsatdrspySKAEIFSL 434
Cdd:cd01347   289 SGYSSERDTTQLGFDAGLNAPFGtGPVAHTLTLGVEYRREE-------------------------------LDEKQTAL 337
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 435 FAENNMELTDSTIVTPGLRFDHHSI--------------VGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNY 500
Cdd:cd01347   338 YAQDTIELTDDLTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGG 417
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 501 ilyskgqgcyaSAGGCYLQGNDDLKAETSINKEIGLEFKRD-GWLAGVTWFRNDYRNKIEAGYVAVGQNAVgtdlYQWDN 579
Cdd:cd01347   418 -----------SHGGTAAVGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEIVSTPTNTGLGLV----TVYVN 482
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 580 VPKAVVEGLEGSLNVPVSETVMWTNNITYM----LKSENKTTGDRLSIIPEYTLNSTLSWQA-REDLSMQTTFTWYGKQQ 654
Cdd:cd01347   483 GGKARIRGVELEASYDLTDGLGLTGSYTYTdtevKRTDGATTGNRLPGIPKHTANLGLDYELpDEGLTAGGGVRYRGKQY 562
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 655 PKKYNykgqpavGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRagnaqttgdlagANYIAGAGAYTYNEP 734
Cdd:cd01347   563 ADTAN-------GNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYT------------SLSVRGSGLYGYYGP 623
                         730
                  ....*....|..
gi 1425613064 735 GRTWYMSINTHF 746
Cdd:cd01347   624 GRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
8-694 5.24e-121

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 375.73  E-value: 5.24e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   8 LALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTA---AEQNLQAPG-VSTITADEIRKNPvARDVSEIIRTMPGVNLTgns 83
Cdd:COG4771     2 LLASLLLLLALAAQAADALAEDATELEEVVVTAtrtEQSLSDAPAsVSVITAEEIEKLG-ATDLADALRLLPGVSVT--- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  84 TSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNsvrqgwrgeRDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGV 163
Cdd:COG4771    78 RSGGRGGSSGISIRGLGGDRVLVLIDGVPVNNPA---------LGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGV 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 164 VNIITKKGSGEWHGSWDAYFNAPEHkeegATKRTNFSLTGPlGDEFSFRLYGNLDKTQADAwdinqghqsaragTYATTL 243
Cdd:COG4771   149 INIITKKPTDELEGSVSLGYGSNGN----GTYSGSLSLGGP-GDKLSFLLSGSYRDRDGYL-------------DYRNGG 210
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 244 PAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRlyRQNYSLTWNGGWDNGV 323
Cdd:COG4771   211 FVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTD--RGNYSLRYNGDLGDNL 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 324 TTSnwVQYEHTRNSRIPEGLAGGtegkfnekaTQDFVDIDLDDVMLHSEVNLPIDflVNQTLTLGTEWNQQRMKDLSSNT 403
Cdd:COG4771   289 DLS--LYYSRTDRDSTNGSLGGS---------TGSFSDSDDTTYGLELDLTYPLG--GNHTLTLGAEYRYDDLDSSSFLG 355
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 404 QALTGTNTggaidgvsatdrspyskaeiFSLFAENNMELTDSTIVTPGLRFDHHSIVG----NNWSPALNISQGLGDDFT 479
Cdd:COG4771   356 GADASRDT--------------------YGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLT 415
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 480 LKMGIARAYKAPSLYQTNPNYILYskgqgcyasaGGCYLQGNDDLKAETSINKEIGLEFK--RDGWLAGVTWFRNDYRNK 557
Cdd:COG4771   416 LRASYGRGFRAPSLAELYGSGTGT----------PGRYVLGNPDLKPETSDNYELGLEYRlgNGGLSLSLTGFYTDIKDL 485
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 558 IEAGYVAVGQNAVgtdlYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYM-LKSENKTTGDRLSIIPEYTLNSTLSWQ 636
Cdd:COG4771   486 IVLVPVGPGPGDV----LQYENVGKARTYGLELELKYRLGKGLTLTASYTYLdSKIDDGDTGEPLPNVPPHKANLGLDYR 561
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1425613064 637 AREDLSMQTTFTWYGKQQPKKYNYkgqpavgPETKEISPYSIVGLSATWDVTKNVSLT 694
Cdd:COG4771   562 LPKWWLLLLLTRYYGGRYVTPPSG-------RLEGYTPGYTLLDLRASYKLTKNLTLS 612
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
279-743 8.43e-47

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 173.42  E-value: 8.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 279 GNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEkaTQD 358
Cdd:pfam00593  35 DGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLS--DDR 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 359 FVDIDLDDVMLHSEVNLPIDFLV-NQTLTLGTEWNQQRMKDLSSNTQAltgtntggaidgVSATDRSPYSKAEIFSLFAE 437
Cdd:pfam00593 113 LYGLYGLDGDLELSLDLSHDLLLgVELRTAGLDYRRLDDDAYDPYDPA------------NPSSSSYSDTTTDSYGLYLQ 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 438 NNMELTDSTIVTPGLRFDHHSIVGNN--------------WSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYily 503
Cdd:pfam00593 181 DNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSG--- 257
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 504 skgqgcYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIeagYVAVGQNAVGTDLYQWDNVPKA 583
Cdd:pfam00593 258 ------SGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLI---TSDPDGPGLGGTVYTYTNVGKA 328
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 584 VVEGLEGSLNVPVSETVMWTNNITYMLKSENK---TTGDRLSIIPEYTLNSTLSWQ-AREDLSMQTTFTWYGKQQPKKYN 659
Cdd:pfam00593 329 RIRGVELELSGRLWGLGLSGGGYTYTDADDDAdadDTGNPLPNVPRHTANLGLTYDfPLGGWGARLGARYVGSGERRYGD 408
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 660 YKGqpavgpeTKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRagnaqttgdlagANYIAGAGAYTYNEPGRTWY 739
Cdd:pfam00593 409 AAN-------TFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKR------------YYSSGGGNLGGYPGPGRTFY 469

                  ....
gi 1425613064 740 MSIN 743
Cdd:pfam00593 470 LGLS 473
 
Name Accession Description Interval E-value
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
1-746 0e+00

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 1465.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   1 MNKKIHSLALLVNLGIYGVAQAQEPT-----DTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSEIIRTMP 75
Cdd:PRK13524    1 MNKKIHSLALLVNLGIYGVAQAAEAEdaktdDTPASHEDTIVVTAAEQNLQAPGVSTITAEDIRKRPPANDVSEIIRTMP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  76 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARY 155
Cdd:PRK13524   81 GVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRYGWRGERDTRGDTNWVPPEMIERIEVLRGPAAARY 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 156 GNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQADAWDINQGHQSAR 235
Cdd:PRK13524  161 GNGAAGGVVNIITKKPTGEWHGSWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSFRLYGNLNKTQADAWDINQGHQSAR 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 236 AGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYSLTW 315
Cdd:PRK13524  241 TGSYAGTLPAGREGVINKDINGLLRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDALVKSLYGKETNRMYRQNYALTH 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 316 NGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQdFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQR 395
Cdd:PRK13524  321 RGGWDNGVSTSNYAQYEHTRNSRLPEGLAGGTEGIFNEKATQ-FSTIDLDDVMLHSEVNLPFDLLVNQTLTLGTEWNQQR 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 396 MKDLSSNTQALTgtnTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLG 475
Cdd:PRK13524  400 MKDPSSNTQALT---SGGAIPGVSATGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLG 476
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 476 DDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYASA-GGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDY 554
Cdd:PRK13524  477 DDFTLKMGIARAYKAPNLYQTNPNYILYSKGQGCYASAgNGCYLQGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDY 556
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 555 RNKIEAGYVAVGQNAVG-TDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTL 633
Cdd:PRK13524  557 RNKIEAGYVPVGTNSVGkTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLQSKNKTTGDPLSIIPEYTLNSTL 636
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 634 SWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQT 713
Cdd:PRK13524  637 SWQATEDLSLQSTFTWYGKQKPKKYNYKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKRLWREGNAQT 716
                         730       740       750
                  ....*....|....*....|....*....|...
gi 1425613064 714 TGdlagaNYIAGAGAYTYNEPGRTWYMSINTHF 746
Cdd:PRK13524  717 TG-----DLIAGAGAYTYNEPGRTYYMSLNTHF 744
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
2-746 0e+00

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 991.57  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   2 NKKIHSLALLVNLGIYGVAQAQEPTDTPVshDDTIVVTAAEQNL-QAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLT 80
Cdd:PRK13528    6 NKILWLLTVLLVGLNSPVSAAESSDDDNG--ETMVVEATAEQELkQQPGVSIITAEDIKKRPPVNDLSDIIRKMPGVNLT 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  81 GNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA 160
Cdd:PRK13528   84 GNSASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEMVERIEVIRGPAAARYGSGAA 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 161 GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPL-GDEFSFRLYGNLDKTQADAWDINQGHqsaragty 239
Cdd:PRK13528  164 GGVVNIITKRPTNDWHGSLSLYTNQPESSKEGATRRANFSLSGPLaGDALTMRLYGNLNKTDADSWDINSSA-------- 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 240 ATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRS--KYGDETNRLYRQNYSLTWNG 317
Cdd:PRK13528  236 GTKNAAGREGVRNKDINGVLSWKMTPQQILDFEAGYSRQGNIYAGDTQNSNSSAVTESlaKSGKETNRLYRQNYGLTHNG 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 318 GWDNGvTTSNWVQYEHTRNSRIPEGLAGGTEGKFNekATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMK 397
Cdd:PRK13528  316 IWDWG-QSRLGFYYEKTNNTRMNEGLAGGGEGRIT--ADQTFTTSRLESYRTSGELNVPLNWLFEQTLTVGAEWNRDELN 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 398 DLSSNTQaltgTNTGGAIDGVS--ATDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLG 475
Cdd:PRK13528  393 DPSSTSL----TVKDGDIGGISgsAADRSSKNKSEISALYVEDNIEPVPGTNLIPGLRFDYHSEFGSNWSPSLNLSQELG 468
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 476 DDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYAS--AGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRND 553
Cdd:PRK13528  469 DYFKVKAGIARAFKAPNLYQSSEGYLLYSRGNGCPKDitSGGCYLVGNKNLDPEISVNKEIGLEFTVDDYHASVTYFRND 548
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 554 YRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPV-SETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNST 632
Cdd:PRK13528  549 YQNKIVAGDDVIGRTASGAYILQWQNGGKAVVEGLEGNLLVPLmKDRLNWNTNATYMITSEQKDTGNPLSVIPKYTINST 628
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 633 LSWQAREDLSMQTTFTWYGKQQPKKYN-YKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNa 711
Cdd:PRK13528  629 LDWQITQALSANVNWTLYGKQKPRTHAeSRSEETGGLSGKELGAYSLVGVNVNYDINKNLRLNVGVSNLFDKQIYREGE- 707
                         730       740       750
                  ....*....|....*....|....*....|....*
gi 1425613064 712 qttgdlaganyiagaGAYTYNEPGRTWYMSINTHF 746
Cdd:PRK13528  708 ---------------GANTYNEPGRAYYAGVTASF 727
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
50-746 1.58e-145

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 440.70  E-value: 1.58e-145
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  50 VSTITADEIRKNPvARDVSEIIRTMPGVNLTGNSTSGQRGNnrqIDIRGMGPEntlILIDGkpvSSRNSVRQGWRGerdt 129
Cdd:TIGR01783   6 VSVITRQELEDQQ-AGSLSEALQRVPGVVVGGSGGTTQFGN---ITIRGFGLE---VDIDN---VYLDGVPLLSRG---- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 130 rgDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEwhgswdAYFNAPEHKEEGATKRTNFSLTGPLGDEF 209
Cdd:TIGR01783  72 --NLAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDE------PKGSVTFGAGTRSGYRTAFDLGGPLGADG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 210 SFRLYGNLDKTQADAWDINQGHQSaRAGTYATTLPAgrEGVINKDINGVVRWDFAPLQSLELEA-----GYSRQGNLYAG 284
Cdd:TIGR01783 144 TFRGRLNGARQDGDSFYDGAGEET-RLGATATDWQL--DDRTLLRLGAYYQKERDRGGYGGLPAsggtsGRDLSSDRYLG 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 285 DTQNTNSDSYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHTRNSripEGLAGGTEGKFNEKatQDFVDIDL 364
Cdd:TIGR01783 221 TSSNRNYDDREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSD---GGLFGRSLTVVNVK--QDRVQIDA 295
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 365 DDVMLHSEVNLPIDFLVNQ-TLTLGTEWNQQrMKDLSSNTQALTGTNTGGAIDGVSATDRSPYSKAEIFSLFAENNMELT 443
Cdd:TIGR01783 296 GLDGEFETGPIEHDLLLGVsYGQRTTNRFNN-TGYPSDNIYSLTATSSARTDIGDSPKDRALSSTTKALNGVALQRILLA 374
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 444 DSTIVTPGLRFDHHSIVGNNwspALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYAsagGCYLQGNDD 523
Cdd:TIGR01783 375 DKWTLTLGGRYDSVDVKSNN---GVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYP---KGAGNSGDI 448
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 524 LKAETSINKEIGLEFKR-DGWLAGVTWFRNDYRNKIEAGyVAVGQNAVGTDLYQWDNVPKAVVEGLegSLNVPVSETVMW 602
Cdd:TIGR01783 449 LEPEKGKNYELGVRYDLgDSLLATAALFRITKDNQLVQD-PVNGTFSVNAGKTRNRGVELEARGYL--TPGLSLSAGYTY 525
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 603 TNNITYMLKSENkTTGDRLSIIPEYTLNSTLSWQAREDlSMQTTFTWYGKQQPKKYnykgqpAVGPETKEISPYSIVGLS 682
Cdd:TIGR01783 526 TDAEFTEDTNGD-TQGNTVPFVPKHTASLWASYAPPVG-DNGLTLGGGVQYTGKAY------VDGGNTGKVPSYTVVDLS 597
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1425613064 683 ATWDVT--KNVSLTGGVDNLFDKRLWRAGNAQTTgdlaganyiagaGAYTYNEPGRTWYMSINTHF 746
Cdd:TIGR01783 598 VRYDLTkkKNLTLALNVNNLFDRDYYTSGYRWGP------------SAYIYPGAPRTVGLSVSYDF 651
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
49-746 3.49e-136

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 416.08  E-value: 3.49e-136
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  49 GVSTITADEIRKNPvARDVSEIIRTMPGVNLTGNStsgqRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGwrgerd 128
Cdd:cd01347     1 SVSVITAEDIEKQP-ATSLADLLRRIPGVSVTRGG----GGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGV------ 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 129 trgDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPehkEEGATKRTNFSLTGPLGDE 208
Cdd:cd01347    70 ---DLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSD---NSGSSGGGGFDVSGALADD 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 209 --FSFRLYGNLDKTQADAWDInqghqsaragtyattLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDT 286
Cdd:cd01347   144 gaFGARLYGAYRDGDGTIDGD---------------GQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGT 208
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 287 QNTNS---------DSYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNW-VQYEHTRNSRIPEGLAGGTEGKFNEKA- 355
Cdd:cd01347   209 LPANGtgsslgggpSSNTNGDRDWDYRDRYRKRASLGLEHDLNDTGWTLRAnLSYSYTDNDGDPLILNGGNNAAGGDLGr 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 356 TQDFVDIDLDDVMLHSEVNLPID-FLVNQTLTLGTEWNQQRmkdlssntqaltgtntggaidgvsatdrspySKAEIFSL 434
Cdd:cd01347   289 SGYSSERDTTQLGFDAGLNAPFGtGPVAHTLTLGVEYRREE-------------------------------LDEKQTAL 337
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 435 FAENNMELTDSTIVTPGLRFDHHSI--------------VGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNY 500
Cdd:cd01347   338 YAQDTIELTDDLTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGG 417
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 501 ilyskgqgcyaSAGGCYLQGNDDLKAETSINKEIGLEFKRD-GWLAGVTWFRNDYRNKIEAGYVAVGQNAVgtdlYQWDN 579
Cdd:cd01347   418 -----------SHGGTAAVGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEIVSTPTNTGLGLV----TVYVN 482
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 580 VPKAVVEGLEGSLNVPVSETVMWTNNITYM----LKSENKTTGDRLSIIPEYTLNSTLSWQA-REDLSMQTTFTWYGKQQ 654
Cdd:cd01347   483 GGKARIRGVELEASYDLTDGLGLTGSYTYTdtevKRTDGATTGNRLPGIPKHTANLGLDYELpDEGLTAGGGVRYRGKQY 562
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 655 PKKYNykgqpavGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRagnaqttgdlagANYIAGAGAYTYNEP 734
Cdd:cd01347   563 ADTAN-------GNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYT------------SLSVRGSGLYGYYGP 623
                         730
                  ....*....|..
gi 1425613064 735 GRTWYMSINTHF 746
Cdd:cd01347   624 GRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
8-694 5.24e-121

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 375.73  E-value: 5.24e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   8 LALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTA---AEQNLQAPG-VSTITADEIRKNPvARDVSEIIRTMPGVNLTgns 83
Cdd:COG4771     2 LLASLLLLLALAAQAADALAEDATELEEVVVTAtrtEQSLSDAPAsVSVITAEEIEKLG-ATDLADALRLLPGVSVT--- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  84 TSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNsvrqgwrgeRDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGV 163
Cdd:COG4771    78 RSGGRGGSSGISIRGLGGDRVLVLIDGVPVNNPA---------LGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGV 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 164 VNIITKKGSGEWHGSWDAYFNAPEHkeegATKRTNFSLTGPlGDEFSFRLYGNLDKTQADAwdinqghqsaragTYATTL 243
Cdd:COG4771   149 INIITKKPTDELEGSVSLGYGSNGN----GTYSGSLSLGGP-GDKLSFLLSGSYRDRDGYL-------------DYRNGG 210
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 244 PAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDSYTRSKYGDETNRlyRQNYSLTWNGGWDNGV 323
Cdd:COG4771   211 FVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTD--RGNYSLRYNGDLGDNL 288
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 324 TTSnwVQYEHTRNSRIPEGLAGGtegkfnekaTQDFVDIDLDDVMLHSEVNLPIDflVNQTLTLGTEWNQQRMKDLSSNT 403
Cdd:COG4771   289 DLS--LYYSRTDRDSTNGSLGGS---------TGSFSDSDDTTYGLELDLTYPLG--GNHTLTLGAEYRYDDLDSSSFLG 355
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 404 QALTGTNTggaidgvsatdrspyskaeiFSLFAENNMELTDSTIVTPGLRFDHHSIVG----NNWSPALNISQGLGDDFT 479
Cdd:COG4771   356 GADASRDT--------------------YGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLT 415
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 480 LKMGIARAYKAPSLYQTNPNYILYskgqgcyasaGGCYLQGNDDLKAETSINKEIGLEFK--RDGWLAGVTWFRNDYRNK 557
Cdd:COG4771   416 LRASYGRGFRAPSLAELYGSGTGT----------PGRYVLGNPDLKPETSDNYELGLEYRlgNGGLSLSLTGFYTDIKDL 485
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 558 IEAGYVAVGQNAVgtdlYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYM-LKSENKTTGDRLSIIPEYTLNSTLSWQ 636
Cdd:COG4771   486 IVLVPVGPGPGDV----LQYENVGKARTYGLELELKYRLGKGLTLTASYTYLdSKIDDGDTGEPLPNVPPHKANLGLDYR 561
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1425613064 637 AREDLSMQTTFTWYGKQQPKKYNYkgqpavgPETKEISPYSIVGLSATWDVTKNVSLT 694
Cdd:COG4771   562 LPKWWLLLLLTRYYGGRYVTPPSG-------RLEGYTPGYTLLDLRASYKLTKNLTLS 612
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
7-746 2.27e-110

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 349.57  E-value: 2.27e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   7 SLALLVNLGIYGVA-QAQEPTDTPVSHDDTIVVTAA--EQNLQ-APG-VSTITADEIRKNPVaRDVSEIIRTMPGVNLTG 81
Cdd:PRK10064    3 RLNPFVRVGLCASAiSCAWPVLAVDDDGETMVVTASavEQNLKdAPAsISVITQEDLQRKPV-QNLKDVLKEVPGVQLTN 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  82 NSTsgqrgNNRQIDIRGMGPENTLILIDGKPVSSRNSVRqgwrgeRDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAG 161
Cdd:PRK10064   82 EGD-----NRKGVSIRGLDSSYTLILIDGKRVNSRNAVF------RHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALG 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 162 GVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDE-FSFRLYGNLDKTQADAwdinqghqSARAGTYA 240
Cdd:PRK10064  151 GVVNIITKKIGQKWHGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGvLGMKAYGSLAKREKDD--------PQNSTTTD 222
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 241 TTLPAGREGVINKDINGVVRWdfAPLQSLELEAGysrqgnlYAGDTQNTNSDSYTRskygdetNRLYRQNYSLTWNGGWD 320
Cdd:PRK10064  223 TGETPRIEGFTSRDGNVEFAW--TPNQNHDFTAG-------YGFDRQDRDSDSLDK-------NRLERQNYSLSHNGRWD 286
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 321 NGVTTSNWVqyehtrNSRIPEGLAGGTEGKFNEKATQDfvdidlddvmlhSEVNLPIDfLVNQTLTLGTEWNQQRMKDLS 400
Cdd:PRK10064  287 YGNSELKYY------GEKVENKNPGNSSPITSESNSID------------GKYTLPLT-AINQFLTFGGEWRHDKLSDAV 347
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 401 SntqaLTGTNTggaidgvSATDRSPYskaeifSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTL 480
Cdd:PRK10064  348 N----LTGGTS-------SKTSASQY------ALFVEDEWRIFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTV 410
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 481 KMGIARAYKAPSLYQTNPNYILYSKGqgcyasaGGCYLQGNDDLKAETSINKEIGLEFK-RDGWLAGV----TWFRNDYR 555
Cdd:PRK10064  411 KGGWATAFKAPSLLQLSPDWTSNSCR-------GACKIVGSPDLKPETSESWELGLYYMgEEGWLEGVessvTVFRNDVD 483
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 556 NKIE----------------AGYVAVGqNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGD 619
Cdd:PRK10064  484 DRISisrtsdvnaapgyqnfVGFETNG-RGRRVPVFRYYNVNKARIQGVETELKIPFNDEWKLSLNYTYNDGRDVSNGEN 562
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 620 R-LSIIPEYTLNSTLSWQAREdlSMQTTFTWYGkqqpkkyNYKGQPAVGPET-KEISPYSIVGLSATWDVTKNVSLTGGV 697
Cdd:PRK10064  563 KpLSDLPFHTANGTLDWKPLA--LEDWSFYVSG-------NYTGQKRADSATaKTPGGYTIWNTGAAWQVTKDVKLRAGV 633
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*....
gi 1425613064 698 DNLFDKRLWRagnaqttgdlaganyiagaGAYTYNEPGRTWYMSINTHF 746
Cdd:PRK10064  634 LNLGDKDLSR-------------------DDYSYNEDGRRYFMAVDYRF 663
PRK13483 PRK13483
ligand-gated channel protein;
7-746 4.40e-102

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 327.89  E-value: 4.40e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   7 SLALLVNLGIYGVAQAQEpTDTPVSHDDTIVVTAA--EQNLQ-APG-VSTITADEIrKNPVARDVSEIIRTMPGVNLTGN 82
Cdd:PRK13483    8 VISALCLLPAVFVTHALA-QAAPDKTMETVVVTASgyEQQIRdAPAsISVITREDL-ENRFYRDLTDALLDVPGVVVTGG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  83 stsgqrGNNRQIDIRGMGPENTLILIDGKPVSSRNSvrqgwRGERDTRG-DTSWVPP-EMIERIEVLRGPAAARYGNGAA 160
Cdd:PRK13483   86 ------GDRTDISLRGMGSQYTLILVDGKRQSSRET-----RPNSDGPGvEQAWTPPlAAIERIEVIRGPMSSLYGSDAI 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 161 GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDE-FSFRLYGNLDKTQADawDINQGHQSARagty 239
Cdd:PRK13483  155 GGVINIITRKVPNEWQGEVRLDTTLQENSDSGNVYQANFFVNGPLIKDlLGLQLYGQYTQREED--DIEGGYRDKD---- 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 240 ATTLPAGREGVINKDingvvrwdfaplQSLELEAGYSRQ---GNLYAGDTQNTNSDSYTRSKYGDETNRLYRQN-YSLTW 315
Cdd:PRK13483  229 ARSLTAKLALTPNED------------HDIMLEVGTSNQerdSTVGKTVAPLAPGESCGRRGCPESSTTEYERStVSLSH 296
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 316 NGGWDNGVTTSnWVQYEHTRN-SRipeglaggtegkfnekatqdfvDIDLDDVMLHSEVNLPIdfLVNQTLTLGTEWNQQ 394
Cdd:PRK13483  297 TGRWDFGTSDT-YIQHEEFDNkSR----------------------EMKIKNTDFQSSLVAPL--GQEHTLTFGAAYNHQ 351
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 395 RMKDLSSNTqaltgtntggaIDGVSATDRSPYskaeifSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGL 474
Cdd:PRK13483  352 DLTDETSNQ-----------ISDLTDISRTQW------AVFSEDEWRIADDFALTGGLRLDHDENFGGHVSPRVYGVWNL 414
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 475 GDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQGCYasaggcylqGNDDLKAETSINKEIGLEF-KRDGWLAGVTWFRND 553
Cdd:PRK13483  415 APSWTVKGGVSTGFRAPSLRQTTPDWGQVSRGGNIY---------GNPDLKPETSLNKELGLYYdLGSGLTASLTVFYNE 485
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 554 YRNKIE-----AGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMlKSENKT---TGDRLSIIP 625
Cdd:PRK13483  486 FKDKITrvacpATQCTDGPNQFGADPTTYVNIDEAVTQGVEASLSYPITSTLSLSGNYTYT-DSEQKSgayKGSPLNQLP 564
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 626 EYTLNSTLSWQAREDLSmqttfTWygkqqpKKYNYKG---QPAVGPETKE-ISP-YSIVGLSATWDVTKNVSLTGGVDNL 700
Cdd:PRK13483  565 KHLFQASLNWEPTDRLN-----SW------ARVNYRGeesQPTTGPSSSSfIAPsYTFLDLGANYQLTDNLKLSAGIYNL 633
                         730       740       750       760
                  ....*....|....*....|....*....|....*....|....*.
gi 1425613064 701 FDKRLwragnaqttgdlagaNYIagagAYTYNEPGRTWYMSINTHF 746
Cdd:PRK13483  634 FDKEI---------------NYE----EYGYVEDGRRYWLGMTYSF 660
PRK13513 PRK13513
ligand-gated channel protein;
1-705 2.67e-90

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 296.68  E-value: 2.67e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   1 MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAA--EQNLQ-APG-VSTITADEIRKNPVaRDVSEIIRTMPG 76
Cdd:PRK13513    3 QRFRKTHKAALVIAAAISSQAYAAEKTNTATPTDTMVVTASgfQQRIQdAPAsISVVTREQLENKAY-RDVTDALKDVPG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  77 VNLTGNstsgqrGNNRQIDIRGMGPENTLILIDGKPVSSRNSvrqgwRGERDTRG-DTSWVPP-EMIERIEVLRGPAAAR 154
Cdd:PRK13513   82 VVVTGG------GSTSDISIRGMAAKYTLILVDGKRVDTRST-----RPNSDGSGiEQGWLPPlAAIERIEVVRGPMSSL 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 155 YGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDE-FSFRLYGNLDKTQADAWDINQGHQS 233
Cdd:PRK13513  151 YGSDAMGGVINIITRKVQKEWHGSLRADATLQEDSKSGDIFQTNAYASGPLIDGlLGLKVSGLLSHRSEDKIIDGYNEQR 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 234 ARAGTYATTLPAGREgvinkdingvvrwdfaplQSLELEAGYSRQG-NLYAGDTQNTNSdsytrskyGDETNRLYRQNYS 312
Cdd:PRK13513  231 MRNGTATFSLTPDDN------------------NEFDFEIGRYVQDrNSTPGRTLALNG--------TNSDTQYDRNNYA 284
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 313 LTWNGGWDNGVTTSnWVQYEHTRN-SRipeglaggtegkfnekatqdfvDIDLDDVMLHSEVNLPIDflvNQTLTLGTEW 391
Cdd:PRK13513  285 ITHNGYYDFGNSTS-YIQRDETRNpSR----------------------QMKSVDTIFNTQTSFLLD---DHTLSLGGQY 338
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 392 NQQRMKDlssntqaltGTNTGGAIDGVSATDRspYSKAeifsLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNIS 471
Cdd:PRK13513  339 RYEELYD---------KGNQLPSASDLNKLTR--WSWA----LFAEDEWQMTNDFALTGGIRMDQDQNYGTHWTPRLYGV 403
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 472 QGLGDDFTLKMGIARAYKAPSLYQTNPNYilyskGQgcyASAGGCY---LQGNDDLKAETSINKEIGLEF-KRDGWLAGV 547
Cdd:PRK13513  404 WHLADQWTLKGGVSTGYRSPDLRQATDNW-----GQ---LTGGGGLpalILGNSDLKPEKSISQEIGILWdNQENLNASV 475
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 548 TWFRNDYRNKIEAGYVAVGQNA-----VGTDLYQW----DNVPKAVVEGLEGSLNVPVSETVMWTNNITYMlKSENKT-- 616
Cdd:PRK13513  476 TLFNTDFKDKITEVRNCDTTNTdgqcvFNGINYDFisdrINVDKANMRGVEATFNWDINQAWSLATNYTFT-QSEQKSga 554
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 617 -TGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQpkkyNYKGQPAVGpetKEISPYSIVGLSATWDVTKNVSLTG 695
Cdd:PRK13513  555 fAGQPLNQMPKHMANATLNWQTTEDFATWIRINYRGKTS----EYLNRTSMG---SGTPSYTFVDLGASYQLTKELRLMG 627
                         730
                  ....*....|
gi 1425613064 696 GVDNLFDKRL 705
Cdd:PRK13513  628 GVYNLLDKRV 637
OM_channels cd01345
Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in ...
464-743 1.08e-89

Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20), which associate as trimers. Maltoporin-like channels have specificities for various sugars and form 18 beta-stranded barrels (18,22), which associate as trimers. Ligand-gated protein channels cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force and they form monomeric, (22,24) barrels. The 150-200 N-terminal residues form a plug that blocks the channel from the periplasmic end.


Pssm-ID: 238655 [Multi-domain]  Cd Length: 253  Bit Score: 281.63  E-value: 1.08e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 464 WSPALNISQGLG----DDFTLKMGIARAYKAPSLYQTNPNyilyskgqgcyasaggcylqgNDDLKAETSINKEIGLEFK 539
Cdd:cd01345     7 FNPVLNIRQGLGqtpdDDLTLK*GYARANKAPSLYQTNPG---------------------NDDAKAETSDGKEIGLEFK 65
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 540 R-DGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTg 618
Cdd:cd01345    66 RdGGWLAGVTYARNDYTNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETV*WTNNYTY*LKSENKTT- 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 619 dRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYnykgqpavgpetKEISPYSIVGLSATWDVTKNVSLTGGVD 698
Cdd:cd01345   145 -RLSIIPEYTLNVTLSWQAREDLS*QVTYTWYKKQQPKKY------------KEIDPYSIVGLSATWDVTKNVSLTGGYD 211
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1425613064 699 NLFDKRLWRAGNAQTTGDlagANYIAGAGAYTYNEPGRTWYMSIN 743
Cdd:cd01345   212 NLFDKRLWRAGNAQTTGD---ANYIAGAGAYTYNEPGDTWY*GVN 253
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
34-704 1.49e-77

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 263.02  E-value: 1.49e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  34 DTIVVTA---AEQNLQAPG-VSTITADEIRKNPVArDVSEIIRTMPGVNLTGNStsgqrgNNRQIDIRGMGPENTLILID 109
Cdd:PRK13484   31 DTLVVTAsgfTQQLRNAPAsVSVITSEQLQKKPVS-DLVDAVKDVEGISITGGN------EKPDISIRGLSGDYTLILVD 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 110 GKPVSSRNSVRQGWRGErdtrgDTSWVPP-EMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGE-WHGSWDAYFNAPE 187
Cdd:PRK13484  104 GRRQSGRESRPNGSGGF-----EAGFIPPvEAIERIEVIRGPMSSLYGSDAIGGVINIITKPVNNQtWDGVLGLGGIIQE 178
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 188 HKEEGATKRTNFSLTGPL-GDEFSFRLYGNLDKTQADAwdINQGHqsaragtyattlpaGREGviNKDINGVVRWDFAPL 266
Cdd:PRK13484  179 HGKFGNSTTNDFYLSGPLiKDKLGLQLYGGMNYRKEDS--ISQGT--------------PAKD--NKNITATLQFTPTES 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 267 QSLELEAGY-SRQGNLYAGDTQN--TNSDSYTRSKYGDETNRlYRQNYSLTWNGGWDngVTTSNWVQY-EHTRNSRIPEG 342
Cdd:PRK13484  241 QKFVFEYGKnNQVHTLTPGESLDawTMRGNLKQPNSKRETHN-SRSHWVAAWNAQGE--ILHPEIAVYqEKVIREVKSGK 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 343 LAGGTEGKFNEKATQDfvdiDLDDVMLHSEVNLpidFLVNQTLTLGTEWNQQRMKDLSSNTQALTGTNTggaidgVSATD 422
Cdd:PRK13484  318 KDKYNHWDLNYESRKP----EITNTIIDAKVTA---FLPENVLTIGGQFQHAELRDDSATGKKTTETQS------VSIKQ 384
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 423 RSpyskaeifsLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYil 502
Cdd:PRK13484  385 KA---------VFIENEYAATDSLALTGGLRLDNHEIYGSYWNPRLYAVYNLTDNLTLKGGIAKAFRAPSIREVSPGF-- 453
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 503 yskgqGCYASAGGCYLQGNDDLKAETSINKEIGLEFKR-DGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVP 581
Cdd:PRK13484  454 -----GTLTQGGASIMYGNRDLKPETSVTEEIGIIYSNdSGFSASATLFNTDFKNKLTSYDIGTKDPVTGLNTFIYDNVG 528
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 582 KAVVEGLEGSLNVPVSETVMWTNNITYM---LKSENKT------TGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGK 652
Cdd:PRK13484  529 EANIRGVELATQIPVYDKWHVSANYTFTdsrRKSDDESlngkslKGEPLERTPRHAANAKLEWDYTQDITFYSSLNYTGK 608
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1425613064 653 Q--QPKKYNYKgqpavGPETKeiSPYSIVGLSATWDVTKNVSLTGGVDNLFDKR 704
Cdd:PRK13484  609 QiwAAQRNGAK-----VPRVR--NGFTSMDIGLNYQILPDTLINFAVLNVTDRK 655
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
34-716 6.27e-77

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 260.53  E-value: 6.27e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  34 DTIVVTA---AEQNLQAPG-VSTITADEIRKNPvARDVSEIIRTMPGVNLTGNStsgqrGNNRQIDIRGMG--PENTLIL 107
Cdd:COG1629     2 EEVVVTAtrtDESLQDVPGsVSVISREQLEDQP-ATDLGDLLRRVPGVSVTSAG-----GGAGQISIRGFGggGNRVLVL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 108 IDGKPVSSRNSVRQGWrgerdtrgdtSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNApe 187
Cdd:COG1629    76 VDGVPLNDPSGGDGGL----------SYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGS-- 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 188 hkeeGATKRTNFSLTGPLGDeFSFRLYGNldKTQADAWDINQGHQSaragtyattlpagregvinKDINGVVRWDFAPLQ 267
Cdd:COG1629   144 ----YGTYRASLSLSGGNGK-LAYRLSAS--YRDSDGYRDNSDSDR-------------------YNLRAKLGYQLGDDT 197
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 268 SLELEAGYSRQGNLYAGDTQNTN-------SDSYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNwVQYEHTRNSrip 340
Cdd:COG1629   198 RLTLSASYSDSDQDSPGYLTLAAlrprgamDDGTNPYSNDTDDNTRDRYSLSLEYEHLGDGLKLSAS-AYYRYDDTD--- 273
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 341 egLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNtqaltgTNTGGAIDGVSA 420
Cdd:COG1629   274 --LDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTLLVGLDYQRQDLDGSGYP------LDLGSGSLPTLT 345
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 421 TDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVG----------------NNWSPALNISQGLGDDFTLKMGI 484
Cdd:COG1629   346 SGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVddtvtgtdsasgsrsySAFSPSLGLTYQLSPNLSLYASY 425
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 485 ARAYKAPSLYQTNPNYILYskgqgcyasaggcYLQGNDDLKAETSINKEIGL--EFKRDGWLAGVTWFRNDYRNKIeagY 562
Cdd:COG1629   426 SRGFRAPTFGELYANGTDP-------------YSVGNPDLKPETSTNYELGLryRLLDGRLSLSLALFYSDVDNEI---L 489
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 563 VAVGQNAVGTDLYqWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMlKSENK--------TTGDRLSIIPEYTLNSTLS 634
Cdd:COG1629   490 SVPLPNDSGFSTY-YTNAGKARSYGVELELSYQLTPGLSLNASYSYT-DAKFDddtdgsadLDGNRLPGVPPLTANLGLT 567
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 635 WQAREDLSMQTTFTWYGKQQPKKYNYKGQPavgpetkeiSPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTT 714
Cdd:COG1629   568 YEFPGGWSLGLGVRYVGDRYLDDANTQGAP---------GGYTLVDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRAS 638

                  ..
gi 1425613064 715 GD 716
Cdd:COG1629   639 NV 640
PRK13486 PRK13486
TonB-dependent receptor;
33-746 7.69e-67

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 234.15  E-value: 7.69e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  33 DDTIVVTAA--EQNLQ--APGVSTITADEIRKNPVaRDVSEIIRTMPGVNLtgNSTSGQRGNnRQIDIRGMGPENTLILI 108
Cdd:PRK13486   25 EDVMIVSASgyEKKLTnaAASVSVISQEELQSSQY-HDLAEALRSVEGVDV--ESGTGKTGG-LEISIRGMPASYTLILI 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 109 DGkpvssrnsVRQGWRGERDTRG----DTSWVPP-EMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYF 183
Cdd:PRK13486  101 DG--------VRQGGSSDVTPNGfsamNTGFMPPlAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNADKWLSSVNAGL 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 184 NAPEHKEEGATKRTNFSLTGPL-GDEFSFRLYGNLDKTQADAwdinqghQSARAGTYATTLPAGREGViNKDINGVVRWD 262
Cdd:PRK13486  173 NLQESNKWGNSSQFNFWSSGPLvDDSVSLQVRGSTQQRQGSS-------VTSLSDTAATRIPYPTESQ-NYNLGARLDWK 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 263 FAPLQSLELEAGYSRQgnlyagdtQNTNSDSYTRSKYG--DETNRLYRQNYSLTWNGGWDNGVTTS--NWVQYEHTRNSR 338
Cdd:PRK13486  245 ASEQDVLWFDMDTTRQ--------RYDNRDGQLGSLTGgyDRTLRYERNKISAGYDHTFTFGTWKSylNWNETENKGREL 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 339 IPEGLAGGTEGkfneKATQDfVDIDLDDVMLHSEVNLPIDflVNQTLTLGTEWNQQRMKdlssntqaltgtntggaiDGV 418
Cdd:PRK13486  317 VRSVLKRDKWG----LAGQP-RELKESNLILNSLLLTPLG--ESHLVTVGGEFQSSSMK------------------DGV 371
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 419 SATDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNp 498
Cdd:PRK13486  372 VLASTGETFRQKSWSVFAEDEWHLTDALALTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLH- 450
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 499 nyilysKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKR-DGWLAGVTWFRNDYRNKIEAgyvavgqNAVGTDLYQW 577
Cdd:PRK13486  451 ------KGISGVSGQGKTNLLGNPDLKPEESVSYEAGVYYDNpAGLNANVTGFMTDFSNKIVS-------YSINDNTNSY 517
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 578 DNVPKAVVEGLEGSLNVPV-SETVMWTNNITYMlKSENK---TTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQ 653
Cdd:PRK13486  518 VNSGKARLHGVEFAGTLPLwSEDVTLSLNYTWT-RSEQRdgdNKGAPLSYTPEHMVNAKLNWQITEEVASWLGARYRGKT 596
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 654 QPKKYNYKGQPAVGPETKE-----ISPYSIVGLSATWDVTKNVSLTGGVDNLFDK-----RLWRAGNAQTtgdLAGANYI 723
Cdd:PRK13486  597 PRFTQNYSSLSAVQKKVYDekgeyLKAWTVVDAGLSWKMTDALTLNAAVNNLLNKdysdvSLYSAGKSTL---YAGDYFQ 673
                         730       740
                  ....*....|....*....|...
gi 1425613064 724 AGAGAYTYNEPGRTWYMSINTHF 746
Cdd:PRK13486  674 TGSSTTGYVIPERNYWMSLNYQF 696
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
1-746 1.84e-61

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 219.03  E-value: 1.84e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   1 MNKKIHSLALLvnlgiyGVAQAQEPTDTpvshDDTIVVTA---AEQNLQA-PG-VSTITADEIRKNPvARDVSEIIRTMP 75
Cdd:COG4772     1 MRRALAAALLL------AAAAAAEAATT----LETVVVTGsraAEARLKDvPGsVSVVDREELENQA-ATSLREVLRRVP 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  76 GVNLTGNSTSGQRGNnrqIDIRGMGPE---NTLILIDGKPVSSrnsvrqgwrgerDTRGDTSWV---PPEMIERIEVLRG 149
Cdd:COG4772    70 GVNVQEEDGFGLRPN---IGIRGLGPRrsrGITLLEDGIPIAP------------APYGDPAAYyfpDLERMERIEVLRG 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 150 PAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNapehkeEGATKRTNFSLTGPLGDefsFRLYGNLDKTQADAWdinQ 229
Cdd:COG4772   135 AAALRYGPQTVGGAINFVTRTIPTAFGGELRVTGG------SFGYRRTHASVGGTVGN---FGYLVEYSRKRGDGF---R 202
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 230 GHQSARAgtyattlpagregvinKDINGVVRWDFAPLQSLELEAGYSRQ-GNLYAGDTQ---NTNSDSYTRSKYGDETNr 305
Cdd:COG4772   203 DNSGFDI----------------NDFNAKLGYRLSDRQELTLKFQYYDEdANTPGGLTDaqfDADPRQSYRPADQFDTR- 265
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 306 lyRQNYSLTWNGGWDNGvTTSNWVQY--EHTRNSRIPEGLAG-GTEGKFNEKATQDFVD--IDLDdvmLHSEVNLpidFL 380
Cdd:COG4772   266 --RTQLSLRYEHQLSDN-TTLTTTAYynDFSRNWYIRQNTADpNTPGLGLRGNPRGYRSygIEPR---LTHRFEL---GG 336
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 381 VNQTLTLGTEWNQQRMKDLSsntqaltGTNTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDH---- 456
Cdd:COG4772   337 VPHTLEVGLRYHREEEDRKQ-------YVNTYGQGRSGAGLRRDRRFSADALAAYAQNRFELTGRLTLTPGLRYEHirrd 409
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 457 ---HSIVGNN-----------WSPALNISQGLGDDFTLKMGIARAYKAPSLYQtnpnyILYSKGqgcyasaggcylqGND 522
Cdd:COG4772   410 rtdRYSTRTGgddsgsnsyseFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGD-----LAYGNG-------------GNP 471
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 523 DLKAETSINKEIGLEFKRDGWLAG-VTWFRNDYRNKIEAGYVAVGQNAVgtdlyqWDNVPKAVVEGLEGSLNVPVSET-- 599
Cdd:COG4772   472 DLKPEKSWNYELGTRGRIGNGLSAeVALFYIDYDNELGSCSAAGGDRST------FTNAGETRHQGLELALDYDLLKGgg 545
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 600 --VMWTNNITYmLKSENKTT------GDRLSIIPEYTLNSTLSWQaREDLSMQTTFTWYGKQqpkkYNYKGQPAVGPETK 671
Cdd:COG4772   546 lgLPLFAAYTY-TDAEFTSDfgpvfaGNRLPYVPRHQLTAGLGYE-HGGWTANLNGRYVSEQ----FTDAANTVADGSFG 619
                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1425613064 672 EISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLwragnAQTTGDLAGANYIAGagaytynePGRTWYMSINTHF 746
Cdd:COG4772   620 KIPSYTVLDLSASYDFGKNLSLFAGVNNLFDKRY-----IASRAPNYAAGIRPG--------PPRTVYAGLRLKF 681
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
34-746 6.66e-58

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 209.58  E-value: 6.66e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  34 DTIVVTAAEQNL--------QAPGVSTITADEIRKNPVaRDVSEIIRTMPGVNLTGnstsGQRGNNRQIDIRGMGPENTL 105
Cdd:TIGR01786   1 DTITVTATRTADpqrrdlsvTPASVSVISREQLKSQQV-RNLRDLLRYEPGVSVVE----GGRGGSQGINIRGLDKNRVA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 106 ILIDGkpvssrnsVRQGWR--GERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHgswdayf 183
Cdd:TIGR01786  76 VLVDG--------IRQNTSygGQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLK------- 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 184 napEHKEEGATKRTNFSLTGPLGdEFSFRLYGNLDKTQAD-AWDINQGHqSARAGTYATTLPAGREGVINKDINGV---- 258
Cdd:TIGR01786 141 ---PGKDLGGLSKLGYSSANNRF-TQSVAAAGRNDDVDALvQATYRRGH-ELKNGNKANIGNESKRSKPNPSDYKSqsfl 215
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 259 --VRWDFAPLQSLEL------EAGYSRQGNL-YAGDTQNTNSDSYTRSKYGDETNRLYRQNYSLTWNG--GWDNGVTTSN 327
Cdd:TIGR01786 216 akLGWQLNDAHRLGLsleytqTDYDEPEMTNtSYLTKPLGAPLLSSTVVLGDSKTRDRRTGLDYELNPdnSWLDTVKLAL 295
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 328 WVQYEHTRN--SRIPEGLAGGTEGKFNEKATQDFVDIDLDdvmlhseVNLPIDFLV-NQTLTLGTEWNQQRMKDLSSNTQ 404
Cdd:TIGR01786 296 DKQYIQLYNylNATSASDYPGVDKNGRYKDKYDYYTLGFD-------TNNKIEFSVhSLSLTYGLDRFKDKVSTGDSRRN 368
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 405 ALTGTNTGGAIDGvsatDRSPYsKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVG---------------NNWSPALN 469
Cdd:TIGR01786 369 LPTAAYNLYGYEG----ENRPV-KGSNFGLFLQDNIKLGDWLSLSAGLRYDHYKTDPkadeskdygaisktySRWSPSLG 443
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 470 ISQGLGDDFTLKMGIARAYKAPSLYQtnpnyiLYskGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDgWLAG-VT 548
Cdd:TIGR01786 444 LTYKPTPWLTLYYSYSQGFRAPSFDE------LY--GTGAHPGGGPYTFLPNPNLKPETSKNWEIGINLHFD-QLDFkVS 514
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 549 WFRNDYRNKIEAGY---VAVGQNAVGT-DLYQWDNVPKAVVEGLE--GSLNV--PVSETVMWTNNITYM-LKSENKTTGD 619
Cdd:TIGR01786 515 YFRNDYKDFIDLGIgvtAKGNMAQVGSnTITNYVNIDNARIRGIElsGRYDLgsFFSGPDGWTTTLKYGyTKGKDSDTNP 594
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 620 RLSIIPEYTLNSTLSWQARED-LSMQTTFTWYGKQQPKK---YNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTG 695
Cdd:TIGR01786 595 WLNAITPLKVVLGLGYDHPDEkWGVGLTLTFSGAKDAVDayaTYYENGEAAKAGPLRTPSYTVVDLYGYYKPNKNLTLRF 674
                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1425613064 696 GVDNLFDKRLWRAGNAqttgdlaganYIAGAGAYTYNEPGRTWYMSINTHF 746
Cdd:TIGR01786 675 GVYNLLDRKYTTWESA----------RQAGPLATGYTAPGRNYKASVEYKF 715
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
34-726 5.42e-56

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 203.39  E-value: 5.42e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  34 DTIVVTAA--EQNLQ--APGVSTITADEIRKNPvARDVSEIIRTMPGVNLTGnstsGQRGNNRQIDIRGMGPENTLILID 109
Cdd:TIGR01785   2 DTVTVTATrtRQVLSeaPASVSVISGEQIESKQ-ANNLADALNTVPGVDVTG----GGRPPGQSINIRGLQDNRVLVVVD 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 110 GkpvssrnsVRQGWRGERDTRGDTSWvPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNApehk 189
Cdd:TIGR01785  77 G--------ARQNYQRGGAHNGSLFV-DPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPGQLFGGLA---- 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 190 eegATKRTNFSLTGPLGDEFSFRLYGNLDK-TQADAWDINQGHQSARAgtyattlPAGREGVINKDINGVVRWDFAPLQS 268
Cdd:TIGR01785 144 ---KLSYGSNNNSFGGSVAVAGRLDDNLDAlVAATYRDGGNYRNGNKE-------EATNSAYVQKNLLAKLGWQLDDAQR 213
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 269 LELEAGYSR-QGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGT 347
Cdd:TIGR01785 214 LEFSYFTTEgSLDEAQNSGPGTEYVLGSSSTLLASSTRDRSATLTYNWTPEDNPWLDATASLYYNRTENDNDRSARGVGR 293
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 348 EGKFNEKAtqdfvdidlddvmLHSEVNLPIDFLV--NQTLTLGTEWNQQRMKDLSSnTQALTGTNTGGAIDGVSATdrsp 425
Cdd:TIGR01785 294 EEGYQYTT-------------YGATLQNTSRFDVasWSTLTYGVDWMKDKRRTESF-DPNSVTTIVPNPPSAKEYF---- 355
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 426 yskaeiFSLFAENNMELTDSTI-VTPGLRFDHHSIVGNN-------------WSPALNISQGLGDDFTLKMGIARAYKAP 491
Cdd:TIGR01785 356 ------FGLFLQDNIPLLDDRLtLSAGLRYDHYKLSPKTtadteavdrsysrWSPSLGLSYKPVDWLTLYASYSQGFRAP 429
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 492 SLYQTnpnyilYSKGQGCYASAGGCYLqGNDDLKAETSINKEIGLEFKRDGWLAG-------VTWFRNDYRNKIEAGYVA 564
Cdd:TIGR01785 430 SIDEL------YGTGDHPGTPGGYTFA-PNPNLKPETSKTWELGANLSFDNLLLDndqlqfkVAYFYNDVKDFIDLTIGV 502
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 565 VGQ-NAVGTDLYQWDNVPKAVVEGLEGSLNVpvsETVMWTNNITYM-LKSENKTTGDRLSIIPEYTLNSTLSWQ-AREDL 641
Cdd:TIGR01785 503 TDNvTAGMNNITQYVNIDGARIRGIEASASY---DAGLWATGLSYGyTIGKDQNTNQWLSNIPPLKLVVTVGYRfPDRRL 579
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 642 SMQTTFTWYGKQQPKKYNYKGQPAVGPETkeiSPYSIVGLSATWDVT--KNVSLTGGVDNLFDKRLWRAGNAQTTGdlAG 719
Cdd:TIGR01785 580 DLGAKAAYYERQSESPTTEDVAANGLLTT---PGYTVVDLYATYQPNavKGLTVRFGVNNLTDRKYTPAQSVPGAG--PG 654

                  ....*..
gi 1425613064 720 ANYIAGA 726
Cdd:TIGR01785 655 RNFKGSV 661
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
18-746 3.15e-52

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 193.19  E-value: 3.15e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  18 GVAQAQEPTDTPVSHDDTIVVTA---AEQNLQAPGVSTIT--ADEIRKNP--------------VARDVSEIIRTMPGVN 78
Cdd:COG4773    17 ALAQAAAAAAAEATTLPEVTVTGtaeGTGGYTAKSSSTATklDTPLRETPqsvsvvtrqliedqGATTLDDALRNVPGVT 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  79 LTGNSTSGQRgnnrQIDIRGMGPENtlILIDGKPVSSRNSVRqgwrgerdtrgdtswVPPEMIERIEVLRGPAAARYGNG 158
Cdd:COG4773    97 VSSYDGGGRD----SFSIRGFSIDN--YLRDGLPLGGFGGGQ---------------PDTANLERVEVLKGPAGLLYGAG 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 159 AAGGVVNIITKKGSGEWH-------GSWDAYfnapehkeegatkRTNFSLTGPLGDEFSFRLYGNLDKTQADAWdinQGH 231
Cdd:COG4773   156 SPGGLVNLVTKRPTAEPQgevslsaGSWDTY-------------RATADVGGPLNEDGTLRYRLNAAYEDGDSF---RDG 219
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 232 QSARAGTyattlpagregvinkdINGVVRWDFAPLQSLELEAGY--SRQGNLYAGDTQNTNSDSYTRSK-YGDETNRLYR 308
Cdd:COG4773   220 VDNRRTL----------------IAPSLDWDLTDDTTLTLGAEYqdDDSTGDRGFLPLDGTLLDLPRSTnLGEPWDYYDT 283
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 309 QNYSLTWNGGW--DNGVTTSNWVQYEHTRNSR----------IPEGLAGGTEGKFNEKATQDFVDIDLddvmlhsevNLP 376
Cdd:COG4773   284 ETTTLFAELEHrfNDDWSLRANARYSDSDRDGrsayaygapdAATGTLTRYASARDGDSRSDSLDANL---------NGK 354
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 377 IDFL-VNQTLTLGTEWNQQRMKDLSSNTQALTGTN-TGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRF 454
Cdd:COG4773   355 FETGgLEHTLLVGADYSRYDSDSDSATAGTINIYNpVYGNLPEPDFDASDTDTTTRQTGLYAQDQISLTDRLSLLLGGRY 434
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 455 DHHSIVGNNWSPALNISQGlGDDFTLKMGIaraykapsLYQTNPN---YILYSKG--QGCYASAGGcylqgnDDLKAETS 529
Cdd:COG4773   435 DWYETDSTNRLGGSTTSYD-DSAFTPRAGL--------VYDLTPGlslYASYSESfePQSGADNNG------NPLDPETG 499
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 530 INKEIGL--EFKRDGWLAGVTWFRndyrnkIEAGYVAVgQNAVGTDLYQwdNVPKAVVEGLEGSLNVPVSETVMWTNNIT 607
Cdd:COG4773   500 KQYEAGVkgELFDGRLNATLAVFD------ITQKNVAT-TDPDNPNFYV--QVGEVRSRGVELELSGELTPGLNLIAGYT 570
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 608 YM----LKSENKTTGDRLSIIPEYTLNSTLSWQ----AREDLSMQTTFTWYGKQQPKKYNYKGQPAvgpetkeispYSIV 679
Cdd:COG4773   571 YTdakiTKDADALEGKRLTNVPRHTASLWTTYRfpsgALKGLGLGGGVRYVGERYGDAANTFTLPS----------YTLV 640
                         730       740       750       760       770       780
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1425613064 680 GLSATWDVTKNVSLTGGVDNLFDKRlwragnaqttgdlaganYIAGAGAYTYNEPG--RTWYMSINTHF 746
Cdd:COG4773   641 DAGARYDLGKNWTLQLNVNNLFDKK-----------------YYASSGSRGYVYYGapRNVRLSLSYKF 692
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
50-746 1.21e-50

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 187.78  E-value: 1.21e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  50 VSTITADEIRkNPVARDVSEIIRTMPGVnltgnSTSGQRGNNR-QIDIRGMGPENTlILIDGKPVSSRNSVrqgwrgerd 128
Cdd:COG4774    13 VTVVTRELIE-DQGATSLADALRNVPGV-----TFGAGEGGNGdSFSIRGFSASGD-IYVDGLRDPGQYRR--------- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 129 trgdtswvPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNapehkeEGATKRTNFSLTGPLGDE 208
Cdd:COG4774    77 --------DTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPTDEPFTEVTLTYG------SDGQRRATLDVNGPLGDD 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 209 FSFRLygNLDKTQADAWdinqghqsaragtyattlpagREGVINKD--INGVVRWDFAPLQSLELEAGYSRQGNLY---- 282
Cdd:COG4774   143 LAYRL--NGMYRDSDSY---------------------RDGVDNDRwgIAPSLTWRLGDRTRLTLDYEYQDDDRTPdygv 199
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 283 ----AGDTQNTNSDSYtrskYGDETNRLYRQNYSLTWNGGWD--NGVTTSNWVQYEHT----RNSRIPEGLAGGTegkfn 352
Cdd:COG4774   200 pavaNGRPVDVDRSTF----YGQPDDYSDSETDSATLRLEHDfnDNWTLRNALRYSDYdrdyRNTYPTGGNATGT----- 270
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 353 ekATQDFVDIDLDDVMLHSEVNLPIDFL---VNQTLTLGTEWNQQRMKDLSSNTQALTGT------NTGGAIDGVSATDR 423
Cdd:COG4774   271 --VTRSAYRRDQDNDTLSNQTDLTGKFDtggVKHTLLAGVEYSREDSDNARYSGGGTAPTvnlynpVYGAPVTGPTLGGA 348
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 424 SPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIaraykapsLYQTNPN---Y 500
Cdd:COG4774   349 DNDSRTDTTGLYLQDTISLTDRWSLLAGLRYDRFDTDYTDRTTGATTSSYDDSAFSPRAGL--------VYKPTPNlslY 420
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 501 ILYSKGQGCYASAGGcYLQGNDDLKAETSINKEIGL--EFKRDGWLAGVTWFRNDYRNkieagyvAVGQNAVGTDLYQwd 578
Cdd:COG4774   421 ASYSTSFNPGGGAPS-LSNAGQALDPEKSRQYEVGVkwDLLDGRLSLTAALFRIEKTN-------VRTTDPANPGVYV-- 490
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 579 NVPKAVVEGLEGSLNVPVSETVMWTNNITYM----LKSENKTT-GDRLSIIPEYTLNSTLSWQ-AREDLSMQTTFTWYGK 652
Cdd:COG4774   491 QTGEQRSRGVELEATGELTPGWSVLAGYTYLdaeiTKSANAANvGNRLPNVPRHSASLWTTYDlPLPGLTLGGGVRYVGS 570
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 653 QQpkkynykgqpAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRlwragnaqttgdlaganYIAGAGAYTYN 732
Cdd:COG4774   571 RY----------ADAANTVKLPSYTRFDAGASYRLNKNLTLRLNVNNLTDKR-----------------YYASAYGSGYV 623
                         730
                  ....*....|....*.
gi 1425613064 733 EPG--RTWYMSINTHF 746
Cdd:COG4774   624 TPGapRTVLLSASYRF 639
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
279-743 8.43e-47

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 173.42  E-value: 8.43e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 279 GNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEkaTQD 358
Cdd:pfam00593  35 DGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLS--DDR 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 359 FVDIDLDDVMLHSEVNLPIDFLV-NQTLTLGTEWNQQRMKDLSSNTQAltgtntggaidgVSATDRSPYSKAEIFSLFAE 437
Cdd:pfam00593 113 LYGLYGLDGDLELSLDLSHDLLLgVELRTAGLDYRRLDDDAYDPYDPA------------NPSSSSYSDTTTDSYGLYLQ 180
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 438 NNMELTDSTIVTPGLRFDHHSIVGNN--------------WSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYily 503
Cdd:pfam00593 181 DNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSG--- 257
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 504 skgqgcYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIeagYVAVGQNAVGTDLYQWDNVPKA 583
Cdd:pfam00593 258 ------SGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLI---TSDPDGPGLGGTVYTYTNVGKA 328
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 584 VVEGLEGSLNVPVSETVMWTNNITYMLKSENK---TTGDRLSIIPEYTLNSTLSWQ-AREDLSMQTTFTWYGKQQPKKYN 659
Cdd:pfam00593 329 RIRGVELELSGRLWGLGLSGGGYTYTDADDDAdadDTGNPLPNVPRHTANLGLTYDfPLGGWGARLGARYVGSGERRYGD 408
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 660 YKGqpavgpeTKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRagnaqttgdlagANYIAGAGAYTYNEPGRTWY 739
Cdd:pfam00593 409 AAN-------TFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKR------------YYSSGGGNLGGYPGPGRTFY 469

                  ....
gi 1425613064 740 MSIN 743
Cdd:pfam00593 470 LGLS 473
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
36-339 5.10e-37

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 140.01  E-value: 5.10e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  36 IVVTA--AEQNLQAPG--VSTITADEIRKNPvARDVSEIIRTMPGVNLtgnSTSGQRGNNRQIDIRGMGPENTLILIDGK 111
Cdd:COG4206     1 VVVTAtrLEQSKSDLTgsVTVIDAEELERSG-ATSLADALRRVPGVQV---SSSGGPGSAASISIRGLGSNQTLVLIDGV 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 112 PVssrNSVRQGWRgerdtrgDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNapehkeE 191
Cdd:COG4206    77 PL---NDPSLGGV-------DLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASYG------S 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 192 GATKRTNFSLTGPLGDefsFRLYGNLDKTQADAWDINQGHQSARAGTYATTLpagregvinkdiNGVVRWDFAPLQSLEL 271
Cdd:COG4206   141 FGTRRLSASLSGGAGK---FSYSLSASYRRSDGYRYNDPDLRNNDGYENTSL------------NARLGYKLGDNGSLSL 205
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1425613064 272 EAGYS-RQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHTRNSRI 339
Cdd:COG4206   206 SGGYSdSERGYPGAVGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGL 274
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
1-741 4.17e-36

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 144.75  E-value: 4.17e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   1 MNKKIHSLALLVNLGIYGVAQAQEPtdtpvshdDTIVVTAaeQNLQAPgVSTI-------TADEIRKNPvARDVSEIIRT 73
Cdd:PRK10641    1 MIKKASLLTALSVTAFSGWAQDTSP--------DTLVVTA--NRFQQP-VSTVlapttvvTRDDIDRWQ-SKSVNDVLRR 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  74 MPGVNLTGNSTSGQRGNnrqIDIRGMGPENTLILIDGKPVSsrnsvRQGWRGErdtrGDTSWVPPEMIERIEVLRGPAAA 153
Cdd:PRK10641   69 LPGVDIAQNGGLGQLSS---LFIRGTNSSHVLVLIDGVRLN-----QAGISGS----ADLSQIPISLVQRIEYIRGPRSA 136
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 154 RYGNGAAGGVVNIIT---KKGS----GEWHGSWDAYfnapehkeEGATKRTnfsltgpLGDEFSFRLYGNLDKT-----Q 221
Cdd:PRK10641  137 VYGSDAIGGVVNIITtrdKPGTtlsaGWGSNGYQNY--------DGSTQQQ-------LGDNTRVTLAGDYTYTkgfdvV 201
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 222 ADAwDINQGHQSARAGTYATTLPAGREGVINKDINGVVRwdfaplqsleleaGYsrqgnlyaGDTQNTNSDSYTRSKY-- 299
Cdd:PRK10641  202 AYG-NTGTQAQPDRDGFMSKTLWGGLEHQFNDQWSGFVR-------------GY--------GYDNRTDYDAYYSPGSpl 259
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 300 GDEtnrlyRQNYSLTWNGG--WDNGVTTSNWV-QYEHTRNSRIpeglaGGTEGKFNEKATQDfvDIDLDDVMLHSEVNLP 376
Cdd:PRK10641  260 IDT-----RQLYSQSWDAGlrYNGGIYSSQLIaSYSHSKDYNY-----DPHYGRYDSSATLD--DMKQYNVQWGNTVQVG 327
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 377 idflvNQTLTLGTEWNQQRmkdLSSNTQALTGT----NTGgaidgvsatdrspyskaeifsLFAENNMELTDSTIVTPGl 452
Cdd:PRK10641  328 -----HGNISAGVDWQKQT---TTPGTGYVPDGydqrNTG---------------------IYLTGQQQIGDVTLEGAA- 377
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 453 RFDHHSIVGNN--WSPALniSQGLGDDFTLKMGIARAYKAPSLYQtnpnyiLYSKGqgcyasaggcylqGNDDLKAETSI 530
Cdd:PRK10641  378 RSDDNSQFGWHgtWQTSA--GWEFIDGYRFIASYGTAFKAPNLGQ------LYGFY-------------GNPNLKPEESK 436
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 531 NKEIGLEfkrdGWLAGVTWFRNDYRNKIEagyvavgqNAVGTD--LYQWDNVPKAVVEGLEGSLNVpvsETVMWTNNITY 608
Cdd:PRK10641  437 QWEGGFE----GLTGPVNWRLSGYRNDID--------NLIDYDdhTLKYYNVGKATIKGVEWTGNF---DTGPLTHQVTL 501
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 609 -MLKSENKTTGDRLSIIPEYTLNSTLSWQArEDLSMQTTFTWYGKQQPKKYNykgqpAVGPETKEISPYSIVGLSATWDV 687
Cdd:PRK10641  502 dYVDPRNAITDEPLARRAKQQVKYQLDWQL-YDFDWGVTYQYLGTRYDKDYS-----TYPYQTVKLGGVSLWDLAVSYPV 575
                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1425613064 688 TKNVSLTGGVDNLFDKrlwragNAQTtgdlaganyiagagAYTYNEPGRTWYMS 741
Cdd:PRK10641  576 TSHLTVRGKIANLFDK------DYET--------------VYGYQTAGREYTLS 609
TonB-B12 TIGR01779
TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane ...
7-746 4.99e-36

TonB-dependent vitamin B12 receptor; This model represents the TonB-dependent outer membrane receptor found in gamma proteobacteria responsible for translocating the cobalt-containing vitamin B12 (cobalamin). [Transport and binding proteins, Other, Transport and binding proteins, Porins]


Pssm-ID: 273802 [Multi-domain]  Cd Length: 614  Bit Score: 144.24  E-value: 4.99e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   7 SLALLVNLGIYGVAQAQEPTDTpvshddtIVVTA------AEQNLQApgVSTITADEIRKNPvARDVSEIIRTMPGVNLT 80
Cdd:TIGR01779   9 ALASLLTLCSALHANEAQPLDT-------VVVTAnrfaqtASQTLAP--VTIITRQDIERTQ-AKSLPELLRRLPGVSIA 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  81 GNstsGQRGNNRQIDIRGMGPENTLILIDGkpvssrnsVRQGwrgeRDTRG--DTSWVPPEMIERIEVLRGPAAARYGNG 158
Cdd:TIGR01779  79 QN---GGRGQNTSLFLRGTESDHVLVLIDG--------IRFG----SAAAGaaDFQQLPVELVERIEYVRGPRSSLYGSE 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 159 AAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGAtkrtnfSLTGPLGDEFSFRLYGNLDKTQAdawdINqghqsARAGT 238
Cdd:TIGR01779 144 AIGGVINIITRRRSGGQGTTLSAGLGSLDYQEYSI------ASGVAIGENGWYSVALGTESTKG----IN-----VRPGG 208
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 239 YATTLPaGREGVINKDINGVVRWDFaplqslelEAGYSRQGNLYAGDTQNtnsdSYTRSKYGdetNRLYRQN--YSLTWN 316
Cdd:TIGR01779 209 PGVYDP-DRDGFRSDSLLLGGGHRF--------DESWSLFVNALRYENRN----DYDNYSFG---TRLYKEAekGDQSFT 272
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 317 GGwdngvttsnwvqyEHTRNSRIPEGLAGGT-EGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQ--TLTLGTEWNQ 393
Cdd:TIGR01779 273 GG-------------RQRQSERDVSELTLSTgKSKDWDYAYSKGRYSSTSDTREQRNIQWQNDLLVGDgwVLAGGVDWQK 339
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 394 QRMKDlssntqaltgtntGGAIDGVSATDRSPYskAEIFSLFAENNMELTdstivtpgLRFDHHSIVGNNWSPALNISQG 473
Cdd:TIGR01779 340 DSIIS-------------STADKEDDRSNTAAF--AQVLQQWGQQLLEAS--------LRRDDNQQFGSHTTGSIAWGYQ 396
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 474 LGDDFTLKMGIARAYKAPSLYQT-NPNYilyskgqgcyasaggcylqGNDDLKAETSINKEIGLEfkrdGWLAGVTWFRN 552
Cdd:TIGR01779 397 FIEELRFTASYGTAFKAPNLNQLyYPSY-------------------GNPNLQPETSKSAELGFY----GLFSGGKWSIS 453
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 553 DYRNKIE--AGYVAVGQNavgtdlyQWDNVPKAVVEGLEGSLNvpvSETVMWTNNITYMLK-SENKTTGDRLSIIPEYTL 629
Cdd:TIGR01779 454 GYRTKINdlIDYDSHPKG-------YPNNIGEARIKGVEATAE---FATGGWTHQLSVDLLdAQNVNTGNTLPRRARQMY 523
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 630 NSTLSWqAREDLSMQTTFTWYGKQQPKKYNykgqpAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKrlwrag 709
Cdd:TIGR01779 524 KWNADR-AFEQFDWGASYQYVGKRYDDDYN-----TYPTQNVRLGGYSLLDLRVSYYVTDSWTVQGRIANLFDK------ 591
                         730       740       750
                  ....*....|....*....|....*....|....*..
gi 1425613064 710 NAQTtgdlaganyiagagAYTYNEPGRTWYMSINTHF 746
Cdd:TIGR01779 592 DYET--------------AYGYPQAGRAYYLSIRYQF 614
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
50-163 8.44e-29

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 110.82  E-value: 8.44e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  50 VSTITADEIRKNPvARDVSEIIRTMPGVNltgnSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNsvrqgwrgerDT 129
Cdd:pfam07715   9 VSVVTAEDIEDQG-ATNLADALRGVPGVS----VSSGGGGGGSSISIRGFGSNRVLVLVDGVPLNSGG----------GG 73
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1425613064 130 RGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGV 163
Cdd:pfam07715  74 SVDLNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
3-746 4.24e-15

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 79.47  E-value: 4.24e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   3 KKIHSLALLVNL--GIYGVAQAQePTDTPVSHDDTIVVTAAEQNLQAPGVS----------------TITADEIRKNPVA 64
Cdd:PRK09840   10 RQFHSLAFFAGLciGITPVAQAL-AAEGQTNADDTLVVEASTPSLYAPDQSadpkfsqpladttqtiTVISEQVIKDQGA 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  65 RDVSEIIRTMPGVNL-----TGNSTSGQrgnnrQIDIRGMGPENTlILIDGkpvssrnsVRQGWRGERDTRGdtswvppe 139
Cdd:PRK09840   89 TNLTEALRNVPGVGTffageNGNTTTGD-----AIYMRGFDTSNS-IYVDG--------IRDIGSISRDTFN-------- 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 140 mIERIEVLRGPAAARYGNGAAGGVVNIITKKGSgewhgsWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLygNLDK 219
Cdd:PRK09840  147 -TEQVEVIKGPSGTDYGRSAPTGSINMISKQPR------NDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRL--NVMG 217
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 220 TQADAwdinqghqsaragtyattlpAGREGVINKdingvvRWDFAP-----LQS---LELEAGYSRQGNLYAGDTQNTNS 291
Cdd:PRK09840  218 EKTHD--------------------AGRDKVKNE------RYGVAPsvafgLGTanrLYLNYLHVTQNNTPDGGIPTIGL 271
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 292 DSYT----RSKYGDETNRLYRQNYSLTwNGGWDNGVTTSNWVQYEH-----------TRNSRIPEG-LAGGTEGKFNEKA 355
Cdd:PRK09840  272 PGYSapsaGRAALNHAGKVDTHNFYGT-DSDYDDSTTDTATMRFEHdindnttlrntTRWSRVKQDyLLTAIMGGASNIT 350
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 356 TQDFVDI------------DLDDVMLHSEVNLPIDFL---VNQTLTLGTEWNQQRMKDLSSNTQALTGTN--------TG 412
Cdd:PRK09840  351 TPTPSDVntwtwsrtantkDVSNKILTNQTNLTSTFYtgsIGHDVSTGVEFTRETQTNYGVNPVTLPAVNlyhpdssiHP 430
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 413 GAID--GVSATDRSpyskaEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWS---------PALNISQGLG----DD 477
Cdd:PRK09840  431 GGLTrnGANANGQT-----DTFAIYAFDTLQLTRDWELNGGIRLDNYHTEYDSATacggsgrgaITCPAGVAKGspvtTV 505
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 478 FTLKMGIARAYKAPSLYQTNPN---YILYSKGQgcyASAGGCYLQ----------GNDDLKAETSINKEIGLEF----KR 540
Cdd:PRK09840  506 DTAKSGNLVNWKAGALYKLTENgnvYINYAVSQ---QPPGGSNFAlaqsgsgnsaNRTDFKPQKANTSEIGTKWqvldKR 582
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 541 DGWLAGVtwFRNDYRNKIEagyvavgQNAVGTdlyqWDNVPKAVVEGLEgsLNVPVSETVMWTNNITYMLKSENKTTG-- 618
Cdd:PRK09840  583 LLLTAAL--FRTDIENEVE-------QNDDGT----YSQYGKKRVEGYE--LSVAGNITPAWQVIAGYTQQKATVKNGkd 647
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 619 ------DRLSIIPEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVgpetkeISPYSIVGLSATWDVTKNVS 692
Cdd:PRK09840  648 vaqdgsSSLPYTPEHAFTLWSQYQATDDLSVGGGARYIGSMHRGSDGAVGTPAF------TEGYWVADAKLGYRVNRNLD 721
                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1425613064 693 LTGGVDNLFDKrlwragnaqttgdlagaNYIAG--AGAYTYNePG--RTWYMSINTHF 746
Cdd:PRK09840  722 LQLNVYNLFDT-----------------DYVASinKSGYRYH-PGepRTFLLTANMHF 761
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
34-746 2.92e-13

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 73.52  E-value: 2.92e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  34 DTIVVT----AAEQNLQ----APGV-STITADEIRKNPvARDVSEIIRTMPGVnltgnSTSGQRGNNRQIDIRGMGPENT 104
Cdd:TIGR01782   2 DAVQVTgqraSLEKAIDakrdADSVvDVISAEDIGKLP-DVNVAEALQRVPGV-----SIERDQGEGRYVSVRGLGPSYN 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 105 LILIDGKPVSSrnsvrqgwrGERDTRG-DTSWVPPEMIERIEVLRGPAAARYGnGAAGGVVNIITKKG--SGEWHGSWDA 181
Cdd:TIGR01782  76 RTTLNGRTIAS---------TDSGGRAfSLDLLPSELVSGVEVYKTPTADMDE-GGIGGTVDLRTRSPfdYDGRTLSGSA 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 182 yfnAPEHKEEGATKRTNFSLTGPLGDEF---SFRLYGNLDKTQADawDINQGHQSARAGTYATTlPAGREGVIN------ 252
Cdd:TIGR01782 146 ---QGGYNDLAGKDKPGPRGAASYSWTFgdgQFGVLLSASYQKRD--FAEDNVETENWGTYTSA-DGGAQGLYFprgvry 219
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 253 -------KDINGVVRWDFAPLQSLEL------------------------------------EAGYSRQGNLYAGDTQNT 289
Cdd:TIGR01782 220 rsyrndrERKGVNGSLQWRPSDALELyldtlyskydddetrqqiefrtlnggstvitsnqtaTSGALVQGTVANLQILVE 299
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 290 NSD---------------------------SYTRSKYG-DETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHTRNSRI-- 339
Cdd:TIGR01782 300 ARYneeketttsltlggewtgdrwtldgdlGYSKATRDrPDRVTRFFTAPTPGYDFDYRGGPTLTLGTPADGDDASNYtn 379
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 340 PEGL-----------AGGTEGKFNEKATQDFVDIDL-------------DDVMLHSEVNLPIDFLVNQTLTLGTE----- 390
Cdd:TIGR01782 380 PANGelrrtqisyqkAEDSEDAAQLDATFDGPFTSLkfgvryrrrdktnRGSRYRRSIIGATGASGLAGVPSDLAgagld 459
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 391 -WNQQRMKDLSSNT------QALTGTNTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDH--HSIVG 461
Cdd:TIGR01782 460 gGLGGPLTGWDPADldaflnAARGDAAGGGTYTYASTAPNTYTVTEDTTAAYAMANFDTGLRLRGNVGVRYERtdQTSDG 539
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 462 -----------------------NNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNY--ILYSKGQGCYASaggc 516
Cdd:TIGR01782 540 wqsqpaangtgsvlvpvsadrdyTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFGDLAANTslSDDGTGGTVTVS---- 615
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 517 ylQGNDDLKAETSINKEIGLEFK-RDGWLAGVTWFRNDYRNKI-EAGYVAVGQNAVGTDLYQWD-----NVPKA-VVEGL 588
Cdd:TIGR01782 616 --GGNPDLKPYESDNLDLSLEWYfGPGGLLSAAVFYKDIKNFIvTTTSTETNDGGGGLVVAGVLvsrpvNGGKAgKIRGV 693
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 589 E-------GSLNVPVSETVMWTnNITYmLKSENK-------TTGDRLSIIPEYTLNSTLSWQaREDLSMQTTFTWYGKQq 654
Cdd:TIGR01782 694 ElgyqqtfDFLPGPLSGFGVQA-NYTY-VDSEADpsvdgvqRRKLPLPGLSKNTANATLYYE-KGGFSARLSYNYRSDY- 769
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 655 pkkYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRL-WRAGNAQTTGDlaganyiagagaytYNE 733
Cdd:TIGR01782 770 ---LLDVGGSNINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSrWYTGGKQRPRE--------------YVE 832
                         890
                  ....*....|...
gi 1425613064 734 PGRTWYMSINTHF 746
Cdd:TIGR01782 833 TGRTYMLGLRYKF 845
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
50-171 8.48e-11

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 65.69  E-value: 8.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  50 VSTITADEIRKNPVARDVSEIIRTMPGVNLTgnSTSGQRGNNRQIDIRGM----GPENTLILIDGKPVSSrnsvrqgwrg 125
Cdd:TIGR04056  98 VSTVKAKELKKVPVSNLSNALQGKVAGVIIT--QSSGEPGGDAEIWIRGIssfgGNNSPLYVIDGVPRDN---------- 165
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1425613064 126 erdtrgDTSWVPPEMIERIEVLRGPAA-ARYGNGAAGGVVNIITKKG 171
Cdd:TIGR04056 166 ------GLSDLNPEDIESISVLKDASAtAIYGSRGANGVILITTKRG 206
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
2-240 3.74e-10

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 63.24  E-value: 3.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   2 NKKIHSLALLVNLGIYGVAQAQEPTDTPvsHDDTIVVTAA---EQNLQAPgVSTITADE----------IRKNP-----V 63
Cdd:PRK10044   10 NHSLRKIAVVVATAVSGMSVYAQAAVEP--KEETITVTAApapQESAWGP-AATIAAKRsatgtktdtpIEKTPqsisvV 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  64 ARD---------VSEIIRTMPGVnltgnsTSGQRGNNRQID---IRGMGPENTlilidgkpvsSRNSVRQGWRGERDTRG 131
Cdd:PRK10044   87 TAEemalhqpksVKEALSYTPGV------SVGTRGASNTYDhliIRGFAASGQ----------SQNNYLDGLKLQGNFYN 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 132 DTSwVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGE------WHGSWDAYFnapehkeegatkRTNFSLTGPL 205
Cdd:PRK10044  151 DAV-IDPYMLERAELMRGPVSVLYGKSNPGGLLNMVSKRPTTEplkevqFKMGTDNLF------------QTGFDFSDAL 217
                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1425613064 206 GD--EFSFRLYGNldktqadAWDINQGHQSARAGTYA 240
Cdd:PRK10044  218 DDdgVYSYRLTGL-------ARSANAQQKGSEEQRYA 247
PRK14050 PRK14050
TonB-dependent siderophore receptor;
50-174 4.18e-08

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 56.73  E-value: 4.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  50 VSTITADEIRKNPVARDVSEIIRTMPGVnltgnsTSGQRGNNRQID---IRGMGPENTLILIDGKPVSSrnsvrQGWRGE 126
Cdd:PRK14050   83 VSVVGRQEMDDRGVTNKVDEALRYTPGV------LSQPFGTDGDTDwfyIRGFDATQTGVFLDGLNLFS-----YGFGGF 151
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1425613064 127 RdtrgdtswVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGE 174
Cdd:PRK14050  152 Q--------IDPFMLERVEVLKGPASVLYGGSNPGGIVNMVSKRPLDE 191
PRK14049 PRK14049
ferrioxamine B receptor precursor protein; Provisional
7-215 1.91e-04

ferrioxamine B receptor precursor protein; Provisional


Pssm-ID: 172541 [Multi-domain]  Cd Length: 726  Bit Score: 44.89  E-value: 1.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064   7 SLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN---------------------------LQAP-GVSTITADEI 58
Cdd:PRK14049   12 ALAGTSALALVATAQAQDAGQESVSNEASTALETLVVNggsggvitadgyvatssatgakvdtpfLETPqSISSVTEQQL 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064  59 R-KNPvaRDVSEIIRTMPGVNltgnstsgqrgnnrqIDIRGMGPENTLILIDGKPVSSRNSVRQGWRgerDTRGDTSW-- 135
Cdd:PRK14049   92 KdRNP--QTLLETLAYTPGAR---------------VGAFGFDPRFDAFFVRGFDVTYTGVFRDNLR---QPGASSSIfk 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425613064 136 VPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGE-------WHGSWDAYfnapehkeegatkRTNFSLTGPL--G 206
Cdd:PRK14049  152 TEPYGLEGVSILRGPSSALYGASGAGGLFNLITKRPTEEplrevqvQYGTNNRY-------------QGQFDFSGPVneT 218

                  ....*....
gi 1425613064 207 DEFSFRLYG 215
Cdd:PRK14049  219 DPVYYRLTG 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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