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Conserved domains on  [gi|1425666815|gb|RBU81478|]
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glucosamine-6-phosphate deaminase [Escherichia coli]

Protein Classification

glucosamine/galactosamine-6-phosphate isomerase/deaminase family protein( domain architecture ID 10013934)

glucosamine/galactosamine-6-phosphate isomerase/deaminase family protein similar to Escherichia coli protein YieK

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12358 PRK12358
glucosamine-6-phosphate deaminase;
1-228 1.79e-156

glucosamine-6-phosphate deaminase;


:

Pssm-ID: 183470  Cd Length: 239  Bit Score: 433.79  E-value: 1.79e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   1 MKLIITEDYQEMSRVAAQHLLGYMSKTRRVNLAITAGSTPKGMYEYLITLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTI 80
Cdd:PRK12358    1 MKIIITKDYEEMSRVAAHHLLGYMSKTKRVNLAITAGSTPKGMYEYLITLVKGKAWYDNVHYYNFDEIPFRGKEGEGVTI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  81 TNLRNLFFTPAGIKEENIQKLTIDNYREHDQKLAREGGLDLVVLGLGVDGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA 160
Cdd:PRK12358   81 TNLRNLFFTPAGIKEENIHKLTIDNYREHDQKLARDGGLDLVVLGLGADGHFCGNLPGTTHFHDETVEVPIQGEMVDIVA 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1425666815 161 HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVI 228
Cdd:PRK12358  161 HGELGGDFSLVPDSYVTMGPKSIMAAKNLLLIVNGKGKAQILKKVLQGPVTEDVPASILQLHPNLTVI 228
 
Name Accession Description Interval E-value
PRK12358 PRK12358
glucosamine-6-phosphate deaminase;
1-228 1.79e-156

glucosamine-6-phosphate deaminase;


Pssm-ID: 183470  Cd Length: 239  Bit Score: 433.79  E-value: 1.79e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   1 MKLIITEDYQEMSRVAAQHLLGYMSKTRRVNLAITAGSTPKGMYEYLITLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTI 80
Cdd:PRK12358    1 MKIIITKDYEEMSRVAAHHLLGYMSKTKRVNLAITAGSTPKGMYEYLITLVKGKAWYDNVHYYNFDEIPFRGKEGEGVTI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  81 TNLRNLFFTPAGIKEENIQKLTIDNYREHDQKLAREGGLDLVVLGLGVDGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA 160
Cdd:PRK12358   81 TNLRNLFFTPAGIKEENIHKLTIDNYREHDQKLARDGGLDLVVLGLGADGHFCGNLPGTTHFHDETVEVPIQGEMVDIVA 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1425666815 161 HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVI 228
Cdd:PRK12358  161 HGELGGDFSLVPDSYVTMGPKSIMAAKNLLLIVNGKGKAQILKKVLQGPVTEDVPASILQLHPNLTVI 228
GlcN6P_deaminase cd01399
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ...
 10-228 1.75e-78

GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.


Pssm-ID: 238693 [Multi-domain]  Cd Length: 232  Bit Score: 235.84  E-value: 1.75e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  10 QEMSRVAAQHLLGYMSKTRRVNLAITAGSTPKGMYEYLITLVK-GKPWYDNCYFYNFDEIPFRGKEGEGVTITNLRNLFF 88
Cdd:cd01399     1 EEMSEAAAELIAELIREKPPAVLGLATGSTPLGVYEELIELHKeGGLSFSNVTTFNLDEYVGLPPDHPQSYHYFMRENLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  89 TPAGIKEENIQKLT------IDNYREHDQKLAREGGLDLVVLGLGVDGHFCGNLPNTTHFHE-QTVEFpiqgEMVDIVAH 161
Cdd:cd01399    81 DHIDIKPENIHIPDgnaadlEAECRRYEALIAEAGGIDLQLLGIGENGHIGFNEPGSSLDSRtRVVTL----DESTRQAN 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1425666815 162 GELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVI 228
Cdd:cd01399   157 ARFFDGDEDVPTQAITMGIGTIMKAKEILLLATGEGKAEAVKKALEGPVTEECPASILQLHPNVTVI 223
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 1-228 1.63e-49

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 162.25  E-value: 1.63e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   1 MKLIITEDYQEMSRVAAQHLLGYMSKT----RRVNLAITAGSTPKGMYEYLITLVKGK--PWyDNCYFYNFDE---IP-- 69
Cdd:COG0363     2 MRVIIFPDAEELAAAAAERAAERIAEAiaekGRAVLGLAGGSTPLGLYEELARLHKEGglDW-SRVHVFNLDEyvgLPpd 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  70 ----FRgkegegvtiTNLRNLFFTPAGIKEENI-----QKLTIDNY-REHDQKLAREGGLDLVVLGLGVDGHFCGNLPNT 139
Cdd:COG0363    81 hpqsNR---------RFMREALLDHVDIPPENIhipdgEAEDPEAAaARYEALIAEAGGIDLQLLGIGEDGHIAFNFPGS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815 140 tHFHEQTvEFPIQGEMVDIVAHGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVL 219
Cdd:COG0363   152 -PFLSET-DRVVTLDESTRQANARFFGSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPASIL 229


                  ....*....
gi 1425666815 220 QLHPSLMVI 228
Cdd:COG0363   230 QGHPNVTWF 238
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
7-222 4.93e-17

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 76.89  E-value: 4.93e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   7 EDYQEMSRVAAQHLLGYMSKT----RRVNLAITAGSTPKGMYEYLITLVKGKPWyDNCYFYNFDE--IP-------FRgk 73
Cdd:pfam01182   1 PDAEALAQALAERLAEALEAAlaerGRFTLALSGGSTPKPLYELLAAAPARLDW-SRVHVFWGDErcVPpddpdsnYG-- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  74 egegvtitNLRNLFFTPAGIKEENIqkLTIDNY--------REHDQKLAREGG------LDLVVLGLGVDGHFCGNLPNT 139
Cdd:pfam01182  78 --------MAREALLSHVPIPASNV--HPIPASaadpeeaaAAYEAELRELLPdlelpvFDLVLLGMGPDGHTASLFPGS 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815 140 THFHEQTvefpiqgemvDIVAHgelggdfslVPDSY------VTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVtED 213
Cdd:pfam01182 148 PALEETD----------RLVVA---------VTDSPkppperITLTLPVLNAARRVWFLVTGAGKADALRRALAGDP-DP 207


                  ....*....
gi 1425666815 214 VPASVLQLH 222
Cdd:pfam01182 208 LPAALVRPG 216
 
Name Accession Description Interval E-value
PRK12358 PRK12358
glucosamine-6-phosphate deaminase;
1-228 1.79e-156

glucosamine-6-phosphate deaminase;


Pssm-ID: 183470  Cd Length: 239  Bit Score: 433.79  E-value: 1.79e-156
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   1 MKLIITEDYQEMSRVAAQHLLGYMSKTRRVNLAITAGSTPKGMYEYLITLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTI 80
Cdd:PRK12358    1 MKIIITKDYEEMSRVAAHHLLGYMSKTKRVNLAITAGSTPKGMYEYLITLVKGKAWYDNVHYYNFDEIPFRGKEGEGVTI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  81 TNLRNLFFTPAGIKEENIQKLTIDNYREHDQKLAREGGLDLVVLGLGVDGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA 160
Cdd:PRK12358   81 TNLRNLFFTPAGIKEENIHKLTIDNYREHDQKLARDGGLDLVVLGLGADGHFCGNLPGTTHFHDETVEVPIQGEMVDIVA 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1425666815 161 HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVI 228
Cdd:PRK12358  161 HGELGGDFSLVPDSYVTMGPKSIMAAKNLLLIVNGKGKAQILKKVLQGPVTEDVPASILQLHPNLTVI 228
GlcN6P_deaminase cd01399
GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase ...
 10-228 1.75e-78

GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or deamination. It is the last step of the metabolic pathway of N-acetyl-D-glucosamine-6-phosphate (GlcNAc6P). GlcN6P deaminase is a hexameric enzyme that is allosterically activated by GlcNAc6P.


Pssm-ID: 238693 [Multi-domain]  Cd Length: 232  Bit Score: 235.84  E-value: 1.75e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  10 QEMSRVAAQHLLGYMSKTRRVNLAITAGSTPKGMYEYLITLVK-GKPWYDNCYFYNFDEIPFRGKEGEGVTITNLRNLFF 88
Cdd:cd01399     1 EEMSEAAAELIAELIREKPPAVLGLATGSTPLGVYEELIELHKeGGLSFSNVTTFNLDEYVGLPPDHPQSYHYFMRENLF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  89 TPAGIKEENIQKLT------IDNYREHDQKLAREGGLDLVVLGLGVDGHFCGNLPNTTHFHE-QTVEFpiqgEMVDIVAH 161
Cdd:cd01399    81 DHIDIKPENIHIPDgnaadlEAECRRYEALIAEAGGIDLQLLGIGENGHIGFNEPGSSLDSRtRVVTL----DESTRQAN 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1425666815 162 GELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLMVI 228
Cdd:cd01399   157 ARFFDGDEDVPTQAITMGIGTIMKAKEILLLATGEGKAEAVKKALEGPVTEECPASILQLHPNVTVI 223
NagB COG0363
6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport ...
 1-228 1.63e-49

6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440132 [Multi-domain]  Cd Length: 248  Bit Score: 162.25  E-value: 1.63e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   1 MKLIITEDYQEMSRVAAQHLLGYMSKT----RRVNLAITAGSTPKGMYEYLITLVKGK--PWyDNCYFYNFDE---IP-- 69
Cdd:COG0363     2 MRVIIFPDAEELAAAAAERAAERIAEAiaekGRAVLGLAGGSTPLGLYEELARLHKEGglDW-SRVHVFNLDEyvgLPpd 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  70 ----FRgkegegvtiTNLRNLFFTPAGIKEENI-----QKLTIDNY-REHDQKLAREGGLDLVVLGLGVDGHFCGNLPNT 139
Cdd:COG0363    81 hpqsNR---------RFMREALLDHVDIPPENIhipdgEAEDPEAAaARYEALIAEAGGIDLQLLGIGEDGHIAFNFPGS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815 140 tHFHEQTvEFPIQGEMVDIVAHGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVL 219
Cdd:COG0363   152 -PFLSET-DRVVTLDESTRQANARFFGSIPKVPPQAITLGIPTIMKAREILLLATGENKAEAVAAALEGPVTEEVPASIL 229


                  ....*....
gi 1425666815 220 QLHPSLMVI 228
Cdd:COG0363   230 QGHPNVTWF 238
nagB PRK00443
glucosamine-6-phosphate deaminase; Provisional
 1-228 4.92e-39

glucosamine-6-phosphate deaminase; Provisional


Pssm-ID: 179028 [Multi-domain]  Cd Length: 261  Bit Score: 135.73  E-value: 4.92e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   1 MKLIITEDYQEMSRVAAQHLLGYM-----SKTRRVNLAITAGSTPKGMYEYLITLVK-GKPWYDNCYFYNFDE---IP-- 69
Cdd:PRK00443    1 MRLIILKTAEEVGKWAARHIANRInaflpTKERPFVLGLATGSSPLETYKALIELHKaGKVDFSRVTTFNLDEyvgLPad 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  70 ----FRgkegegvtiTNLRNLFFTPAGIKEENIQKL---TIDNYRE---HDQKLAREGGLDLVVLGLGVDGHFCGNLPNT 139
Cdd:PRK00443   81 hpesYR---------YFMRENFFDHVDIPPENINLLngnAPDPEAEcrrYEEKIKSAGGIDLQILGIGENGHIAFNEPGS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815 140 -----THFHEQTVEFPIQGEMVDivahgelGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDV 214
Cdd:PRK00443  152 sfasrTRIKTLTEDTRIANSRFF-------DGDIEQVPKYALTVGVGTILDAKEIMLLAPGHNKAEAVKAAVEGPVNHMW 224

                         250
                  ....*....|....
gi 1425666815 215 PASVLQLHPSLMVI 228
Cdd:PRK00443  225 PASILQLHPKATLV 238
PRK09762 PRK09762
galactosamine-6-phosphate isomerase; Provisional
 1-223 1.70e-24

galactosamine-6-phosphate isomerase; Provisional


Pssm-ID: 182064  Cd Length: 232  Bit Score: 97.21  E-value: 1.70e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   1 MKLIITEDYQEMSRVAAQHLLGYMSKTRRVNLAITAGSTPKGMYEYLITLVKGKP-WYDNCYFYNFDEIPFRGKEGEGVT 79
Cdd:PRK09762    1 QTLQQVENYTALSERASEYLLAVIRSKPDAVICLATGATPLLTYHYLVEKIHQQQvDVSQLTFVKLDEWVDLPLTMPGTC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  80 ITNLRNLFFTPAGIKEENIQKLTIDNYREHD-----QKLAREGGLDLVVLGLGVDGHFCGNLP--------NTTHFHEQT 146
Cdd:PRK09762   81 ETFLQQHIVQPLGLREDQLISFRSEEINETEcervtNLIARKGGLDLCVLGLGKNGHLGLNEPgeslqpacHISQLDART 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1425666815 147 VEFP-IQGEMVDivahgelggdfslvPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHP 223
Cdd:PRK09762  161 QQHEmLKTAGRP--------------VTRGITLGLKDILNAREVLLLVTGEGKQDATERFLTAKVSTAIPASFLWLHS 224
PRK02122 PRK02122
glucosamine-6-phosphate deaminase-like protein; Validated
 4-228 1.04e-23

glucosamine-6-phosphate deaminase-like protein; Validated


Pssm-ID: 235005 [Multi-domain]  Cd Length: 652  Bit Score: 98.95  E-value: 1.04e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   4 IITEDYQEMSRVAAQHLLGYMSKTRRVN----LAITAGSTPKGMYEYLITLVK--GKPWYDNCYFyNFDEIPFRGKEGEG 77
Cdd:PRK02122   31 DIFESSEEASRAVAQEIATLIRERQAEGkpcvLGLATGSSPIGVYAELIRMHReeGLSFKNVITF-NLDEYYPMQPDSLQ 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  78 VTITNLRNLFFTPAGIKEENI-------QKLTIDNY-REHDQKLAREGGLDLVVLGLGVDGHFCGNLPNTthfHEQTVEF 149
Cdd:PRK02122  110 SYHRFMKENLFDHVDIPPENIhipdgtiPKEEIDEYcRDYEEKIEAAGGIDFQLLGIGRTGHIGFNEPGS---GRNSRTR 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815 150 PIqgeMVDIVAHGELGGDF---SLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHPSLM 226
Cdd:PRK02122  187 LV---TLDHITRRDAASDFfgeENVPRKAITMGVGTILKARRIVLLAWGEHKAPIIKRAVEGEISDEVPASYLQEHPNAT 263


                  ..
gi 1425666815 227 VI 228
Cdd:PRK02122  264 FV 265
PTZ00285 PTZ00285
glucosamine-6-phosphate isomerase; Provisional
 1-224 5.24e-23

glucosamine-6-phosphate isomerase; Provisional


Pssm-ID: 140308  Cd Length: 253  Bit Score: 93.67  E-value: 5.24e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   1 MKLIITEDYQEMSRVAAQHLLGYM-----SKTRRVNLAITAGSTPKGMYEYLITLVK-GKPWYDNCYFYNFDE---IPFR 71
Cdd:PTZ00285    1 MRIVISEDADAVADYTSNYIIKRIndfkpTSDRPFVLGLPTGSTPLPTYQELIRAYReGRVSFSNVVTFNMDEyvgLPRD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  72 GKEGEGVTI-TNlrnlFFTPAGIKEENIQKL--TIDNY----REHDQKLAREGGLDLVVLGLGVDGHFCGNLPNTTHFHE 144
Cdd:PTZ00285   81 HPQSYHYFMkEN----FFDHVDIKEENRHILngTAPDLeeecRRYEEKIRAVGGIDLFLAGIGTDGHIAFNEPGSSLDSR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815 145 QTVEFPIQGEmvdIVAHGEL-GGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHP 223
Cdd:PTZ00285  157 TRVKSLNQET---IDANARFfGNDISKVPTMALTVGIRTIMEAREVLLLATGASKAIAVARCVEGGVTHMCPASALQMHP 233


                  .
gi 1425666815 224 S 224
Cdd:PTZ00285  234 A 234
Glucosamine_iso pfam01182
Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;
7-222 4.93e-17

Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;


Pssm-ID: 460101 [Multi-domain]  Cd Length: 222  Bit Score: 76.89  E-value: 4.93e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815   7 EDYQEMSRVAAQHLLGYMSKT----RRVNLAITAGSTPKGMYEYLITLVKGKPWyDNCYFYNFDE--IP-------FRgk 73
Cdd:pfam01182   1 PDAEALAQALAERLAEALEAAlaerGRFTLALSGGSTPKPLYELLAAAPARLDW-SRVHVFWGDErcVPpddpdsnYG-- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  74 egegvtitNLRNLFFTPAGIKEENIqkLTIDNY--------REHDQKLAREGG------LDLVVLGLGVDGHFCGNLPNT 139
Cdd:pfam01182  78 --------MAREALLSHVPIPASNV--HPIPASaadpeeaaAAYEAELRELLPdlelpvFDLVLLGMGPDGHTASLFPGS 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815 140 THFHEQTvefpiqgemvDIVAHgelggdfslVPDSY------VTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVtED 213
Cdd:pfam01182 148 PALEETD----------RLVVA---------VTDSPkppperITLTLPVLNAARRVWFLVTGAGKADALRRALAGDP-DP 207


                  ....*....
gi 1425666815 214 VPASVLQLH 222
Cdd:pfam01182 208 LPAALVRPG 216
6PGL cd01400
6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the ...
 10-223 1.32e-15

6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.


Pssm-ID: 238694 [Multi-domain]  Cd Length: 219  Bit Score: 72.98  E-value: 1.32e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  10 QEMSRVAAQHLLG----YMSKTRRVNLAITAGSTPKGMYEYLITLvKGKPWyDNCYFYNFDE--IPFrgkEGEGVTITNL 83
Cdd:cd01400     1 EALAEALADRIAEalaaAIAKRGRFSLALSGGSTPKPLYELLAAA-PALDW-SKVHVFLGDErcVPP---DDPDSNYRLA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815  84 RNLFFTPAGIKEENIQKLTIDNY-----REHDQKLAREGG----LDLVVLGLGVDGHFCGNLPNTTHFHEQTvefpiqGE 154
Cdd:cd01400    76 REALLSHVAIPAANIHPIPTELGpedaaAAYEKELRALFGgvppFDLVLLGMGPDGHTASLFPGHPALLEET------DR 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1425666815 155 MVdIVAHGElggdfSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASVLQLHP 223
Cdd:cd01400   150 LV-VAVTDS-----PKPPPERITLTLPVLNNARRVVFLVTGAEKAEALKRALAGPDPEELPAARVLPRP 212
PLN02360 PLN02360
probable 6-phosphogluconolactonase
 120-220 7.31e-03

probable 6-phosphogluconolactonase


Pssm-ID: 166001 [Multi-domain]  Cd Length: 268  Bit Score: 36.76  E-value: 7.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1425666815 120 DLVVLGLGVDGHFCGNLPNTTHFHEQTvefpiqgEMVDIVAhgelggDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKA 199
Cdd:PLN02360  152 DLILLGMGSDGHVASLFPNHPALEEKD-------DWVTFIT------DSPKPPPERITFTLPVINSASNVAVVATGESKA 218

                          90       100
                  ....*....|....*....|....*
gi 1425666815 200 QA----LKNVLQGPVTEDVPASVLQ 220
Cdd:PLN02360  219 NAvhlaIDDVTEGPDAPSLPARMVQ 243
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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