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Conserved domains on  [gi|1433516753|gb|RCW06985|]
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crossover junction endodeoxyribonuclease, partial [Shigella boydii]

Protein Classification

RusA family crossover junction endodeoxyribonuclease( domain architecture ID 10008623)

RusA family crossover junction endodeoxyribonuclease similar to Lactococcus phage RusA that resolves Holliday junction intermediates and promotes DNA repair

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RusA COG4570
Holliday junction resolvase RusA (prophage-encoded endonuclease) [Replication, recombination ...
3-98 1.74e-29

Holliday junction resolvase RusA (prophage-encoded endonuclease) [Replication, recombination and repair];


:

Pssm-ID: 443627  Cd Length: 120  Bit Score: 101.89  E-value: 1.74e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1433516753   3 GKSLISAAGRKFQSAACAAIVEQLRRlpKPTSAPASVEIVL-FPPDNRIRDLDNYNKALFDALTHAGVWEDDRQVKRMLV 81
Cdd:COG4570    22 GRRYTPEKGKAYRNLVALAARQQMPK--KPLEGPVAVEIKFyFPPDRRKPDLDNLLKAILDALTGAGVWKDDSQVVDLIV 99
                          90
                  ....*....|....*..
gi 1433516753  82 EWGPVIPKGKVEITISK 98
Cdd:COG4570   100 EKRYDDKGPRVEVEIEE 116
 
Name Accession Description Interval E-value
RusA COG4570
Holliday junction resolvase RusA (prophage-encoded endonuclease) [Replication, recombination ...
3-98 1.74e-29

Holliday junction resolvase RusA (prophage-encoded endonuclease) [Replication, recombination and repair];


Pssm-ID: 443627  Cd Length: 120  Bit Score: 101.89  E-value: 1.74e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1433516753   3 GKSLISAAGRKFQSAACAAIVEQLRRlpKPTSAPASVEIVL-FPPDNRIRDLDNYNKALFDALTHAGVWEDDRQVKRMLV 81
Cdd:COG4570    22 GRRYTPEKGKAYRNLVALAARQQMPK--KPLEGPVAVEIKFyFPPDRRKPDLDNLLKAILDALTGAGVWKDDSQVVDLIV 99
                          90
                  ....*....|....*..
gi 1433516753  82 EWGPVIPKGKVEITISK 98
Cdd:COG4570   100 EKRYDDKGPRVEVEIEE 116
PRK09786 PRK09786
endodeoxyribonuclease RUS; Reviewed
3-98 1.89e-18

endodeoxyribonuclease RUS; Reviewed


Pssm-ID: 182075  Cd Length: 120  Bit Score: 73.75  E-value: 1.89e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1433516753   3 GKSLISAAGRKFQSAAcAAIVEQlRRLPKPTSAPASVEIVLFPPDNRIRDLDNYNKALFDALTHAGVWEDDRQVKRMLVE 82
Cdd:PRK09786   23 GRTHISAEGQAYRDNV-ARIIKN-AMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVV 100
                          90
                  ....*....|....*.
gi 1433516753  83 WGPVIPKGKVEITISK 98
Cdd:PRK09786  101 KMPVTKGGRLELTITE 116
RusA pfam05866
Endodeoxyribonuclease RusA; This family consists of several bacterial and phage Holliday ...
3-96 5.70e-11

Endodeoxyribonuclease RusA; This family consists of several bacterial and phage Holliday junction resolvase (RusA) like proteins. The RusA protein of Escherichia coli is an endonuclease that can resolve Holliday intermediates and correct the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.


Pssm-ID: 428654  Cd Length: 124  Bit Score: 54.60  E-value: 5.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1433516753   3 GKSLISAAGRKFQSAAcAAIVEQLRRLPKPTSAPASVEIVLFPP------------DNRIR-----DLDNYNKALFDALt 65
Cdd:pfam05866  16 GRTYTPEKTKAYENLV-KLYLAQQMPGRPPLEGPVKVEIKAYFPipkswskkkralEGKIRptkkpDIDNLAKALLDAL- 93
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1433516753  66 HAGVWEDDRQVKRMLVE--WGpviPKGKVEITI 96
Cdd:pfam05866  94 NGGVWKDDSQVVDIIVEkfYS---EEPRVEVEI 123
 
Name Accession Description Interval E-value
RusA COG4570
Holliday junction resolvase RusA (prophage-encoded endonuclease) [Replication, recombination ...
3-98 1.74e-29

Holliday junction resolvase RusA (prophage-encoded endonuclease) [Replication, recombination and repair];


Pssm-ID: 443627  Cd Length: 120  Bit Score: 101.89  E-value: 1.74e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1433516753   3 GKSLISAAGRKFQSAACAAIVEQLRRlpKPTSAPASVEIVL-FPPDNRIRDLDNYNKALFDALTHAGVWEDDRQVKRMLV 81
Cdd:COG4570    22 GRRYTPEKGKAYRNLVALAARQQMPK--KPLEGPVAVEIKFyFPPDRRKPDLDNLLKAILDALTGAGVWKDDSQVVDLIV 99
                          90
                  ....*....|....*..
gi 1433516753  82 EWGPVIPKGKVEITISK 98
Cdd:COG4570   100 EKRYDDKGPRVEVEIEE 116
PRK09786 PRK09786
endodeoxyribonuclease RUS; Reviewed
3-98 1.89e-18

endodeoxyribonuclease RUS; Reviewed


Pssm-ID: 182075  Cd Length: 120  Bit Score: 73.75  E-value: 1.89e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1433516753   3 GKSLISAAGRKFQSAAcAAIVEQlRRLPKPTSAPASVEIVLFPPDNRIRDLDNYNKALFDALTHAGVWEDDRQVKRMLVE 82
Cdd:PRK09786   23 GRTHISAEGQAYRDNV-ARIIKN-AMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVV 100
                          90
                  ....*....|....*.
gi 1433516753  83 WGPVIPKGKVEITISK 98
Cdd:PRK09786  101 KMPVTKGGRLELTITE 116
RusA pfam05866
Endodeoxyribonuclease RusA; This family consists of several bacterial and phage Holliday ...
3-96 5.70e-11

Endodeoxyribonuclease RusA; This family consists of several bacterial and phage Holliday junction resolvase (RusA) like proteins. The RusA protein of Escherichia coli is an endonuclease that can resolve Holliday intermediates and correct the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.


Pssm-ID: 428654  Cd Length: 124  Bit Score: 54.60  E-value: 5.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1433516753   3 GKSLISAAGRKFQSAAcAAIVEQLRRLPKPTSAPASVEIVLFPP------------DNRIR-----DLDNYNKALFDALt 65
Cdd:pfam05866  16 GRTYTPEKTKAYENLV-KLYLAQQMPGRPPLEGPVKVEIKAYFPipkswskkkralEGKIRptkkpDIDNLAKALLDAL- 93
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1433516753  66 HAGVWEDDRQVKRMLVE--WGpviPKGKVEITI 96
Cdd:pfam05866  94 NGGVWKDDSQVVDIIVEkfYS---EEPRVEVEI 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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