|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-468 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 620.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 1 MLKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVN 76
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKElgrpVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 77 kEPIPFKTGEIVkVIGNPDQETSHDCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVN 156
Cdd:COG0469 81 -GPVELKKGDTF-TLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 157 VPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEVAYGV 236
Cdd:COG0469 159 LPGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 237 MIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKY 316
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 317 PIEAVQTMTKVAREAEKTKLSANDIRVPIEGNDLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTSTVFA 396
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILA 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1471120868 397 ICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYLSGS-FGEGGGTSFLEINNV 468
Cdd:COG0469 399 LTPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVpVGVPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-459 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 619.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 1 MLKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVN 76
Cdd:PRK05826 2 MLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKlgrpVAILLDLKGPKIRVGKFKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 77 KePIPFKTGEIVKVIGNPDQETSHDCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVN 156
Cdd:PRK05826 82 G-KITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 157 VPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSP-IKIIAKIENQEGVDNIEEILEVAYG 235
Cdd:PRK05826 161 IPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPhAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 236 VMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 315
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 316 YPIEAVQTMTKVAREAEKtKLSANDIRVPIEGNDLDVTSFLAKQAVKSSSKLH-VKAIITDSYTGRTARYLAAFRGTSTV 394
Cdd:PRK05826 321 YPVEAVEAMARICKGAEK-EFSINLSKHRLDRQFDRIDEAIAMSAMYAANHLKgVKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1471120868 395 FAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYLSGSFGEGGG 459
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
3-465 |
2.67e-173 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 495.65 E-value: 2.67e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 3 KHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSD----RIGILMDTKGPEVRTTTTVNkE 78
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEklgrPVAILLDTKGPEIRTGEIKG-G 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 79 PIPFKTGEIVKVIGNPDQET-SHDCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNV 157
Cdd:TIGR01064 80 EVKLKKGDKVIITTDDIKGEgDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 158 PGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSP-IKIIAKIENQEGVDNIEEILEVAYGV 236
Cdd:TIGR01064 160 PGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKdVKIIAKIENQEGVDNIDEIAEASDGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 237 MIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKY 316
Cdd:TIGR01064 240 MVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 317 PIEAVQTMTKVAREAEKTKLSANDIRvPIEGNDLDVTSF---LAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTST 393
Cdd:TIGR01064 320 PVEAVQMMAKIAKEAEKALAYLTNFN-DRKNSDPKPSTIteaIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAP 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1471120868 394 VFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFY-DALNQLIHSGRITRNDMVAYLSGSF-GEGGGTSFLEI 465
Cdd:TIGR01064 399 IIAVTPNERVARQLALYWGVFPFLVDEEPSDTDARVnKALELLKEKGIVKKGDLVVVIQGGPiGGEGGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
2-465 |
4.84e-156 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 452.15 E-value: 4.84e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 2 LKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVNK 77
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKtggpVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 78 EPIPFKTGEIVKVIGNPDQETSHD-CICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDC-LLCEIQNDATLGSRKSV 155
Cdd:cd00288 81 KDISLKAGDKFLVTTDPAAKKGTKeKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 156 NVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEVAYG 235
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 236 VMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 315
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 316 YPIEAVQTMTKVAREAEKTkLSANDIRVPI---EGNDLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTS 392
Cdd:cd00288 321 YPVEAVKAMARICLEAEKA-LSHRVLFNEMrrlTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 393 TVFAICYNPRVMRMLGLSYGVWAVHqpYNDSRRGYFYD-------ALNQLIHSGRITRNDMVAYLSGSFGEGGGTSFLEI 465
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVL--FEEPKPGWQEDtdarlkaAVNVAKEKGLLKKGDLVVVVQGWPVGSGSTNTMRI 477
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
2-334 |
2.06e-135 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 394.43 E-value: 2.06e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 2 LKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVN- 76
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKtggtVAIALDTKGPEIRTGNTKDg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 77 KEPIPFKTGEIVKVIGNPDQETSHD--CICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGD-CLLCEIQNDATLGSRK 153
Cdd:pfam00224 81 KKDIELKAGDEMIVSTDAKYKGACDdeMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 154 SVNVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEVA 233
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 234 YGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAY 313
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|.
gi 1471120868 314 GKYPIEAVQTMTKVAREAEKT 334
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEKA 341
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-468 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 620.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 1 MLKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVN 76
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKElgrpVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 77 kEPIPFKTGEIVkVIGNPDQETSHDCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVN 156
Cdd:COG0469 81 -GPVELKKGDTF-TLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 157 VPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEVAYGV 236
Cdd:COG0469 159 LPGVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 237 MIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKY 316
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 317 PIEAVQTMTKVAREAEKTKLSANDIRVPIEGNDLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTSTVFA 396
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILA 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1471120868 397 ICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYLSGS-FGEGGGTSFLEINNV 468
Cdd:COG0469 399 LTPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVpVGVPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-459 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 619.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 1 MLKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVN 76
Cdd:PRK05826 2 MLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKlgrpVAILLDLKGPKIRVGKFKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 77 KePIPFKTGEIVKVIGNPDQETSHDCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVN 156
Cdd:PRK05826 82 G-KITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 157 VPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSP-IKIIAKIENQEGVDNIEEILEVAYG 235
Cdd:PRK05826 161 IPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPhAKIIAKIERAEAVDNIDEIIEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 236 VMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 315
Cdd:PRK05826 241 IMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 316 YPIEAVQTMTKVAREAEKtKLSANDIRVPIEGNDLDVTSFLAKQAVKSSSKLH-VKAIITDSYTGRTARYLAAFRGTSTV 394
Cdd:PRK05826 321 YPVEAVEAMARICKGAEK-EFSINLSKHRLDRQFDRIDEAIAMSAMYAANHLKgVKAIVALTESGRTARLISRFRPGAPI 399
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1471120868 395 FAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYLSGSFGEGGG 459
Cdd:PRK05826 400 FAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
3-465 |
2.67e-173 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 495.65 E-value: 2.67e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 3 KHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSD----RIGILMDTKGPEVRTTTTVNkE 78
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEklgrPVAILLDTKGPEIRTGEIKG-G 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 79 PIPFKTGEIVKVIGNPDQET-SHDCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNV 157
Cdd:TIGR01064 80 EVKLKKGDKVIITTDDIKGEgDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 158 PGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSP-IKIIAKIENQEGVDNIEEILEVAYGV 236
Cdd:TIGR01064 160 PGADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKdVKIIAKIENQEGVDNIDEIAEASDGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 237 MIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKY 316
Cdd:TIGR01064 240 MVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 317 PIEAVQTMTKVAREAEKTKLSANDIRvPIEGNDLDVTSF---LAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTST 393
Cdd:TIGR01064 320 PVEAVQMMAKIAKEAEKALAYLTNFN-DRKNSDPKPSTIteaIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAP 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1471120868 394 VFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFY-DALNQLIHSGRITRNDMVAYLSGSF-GEGGGTSFLEI 465
Cdd:TIGR01064 399 IIAVTPNERVARQLALYWGVFPFLVDEEPSDTDARVnKALELLKEKGIVKKGDLVVVIQGGPiGGEGGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
2-465 |
4.84e-156 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 452.15 E-value: 4.84e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 2 LKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVNK 77
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKtggpVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 78 EPIPFKTGEIVKVIGNPDQETSHD-CICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDC-LLCEIQNDATLGSRKSV 155
Cdd:cd00288 81 KDISLKAGDKFLVTTDPAAKKGTKeKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 156 NVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEVAYG 235
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 236 VMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGK 315
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 316 YPIEAVQTMTKVAREAEKTkLSANDIRVPI---EGNDLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTS 392
Cdd:cd00288 321 YPVEAVKAMARICLEAEKA-LSHRVLFNEMrrlTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 393 TVFAICYNPRVMRMLGLSYGVWAVHqpYNDSRRGYFYD-------ALNQLIHSGRITRNDMVAYLSGSFGEGGGTSFLEI 465
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVL--FEEPKPGWQEDtdarlkaAVNVAKEKGLLKKGDLVVVVQGWPVGSGSTNTMRI 477
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-476 |
2.13e-140 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 415.86 E-value: 2.13e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 1 MLKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVN 76
Cdd:PRK06354 6 LMRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKlgktVGILQDLQGPKIRLGRFED 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 77 KePIPFKTGEIV-----KVIGNPDQetshdcICVSYKNFVNDLAIGSDILIDDGDLEMKVTG--KSGDCLLCEIQNDATL 149
Cdd:PRK06354 86 G-PIELKTGDEFiltsrEVLGTQEK------FSVTYDGLADEVPVGSRILLDDGLIELEVEEvdKADGELHCKVLVGGVL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 150 GSRKSVNVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERN-SPIKIIAKIENQEGVDNIEE 228
Cdd:PRK06354 159 SNKKGVNFPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNgKHIPIIAKIEKQEAIDNIDA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 229 ILEVAYGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLS 308
Cdd:PRK06354 239 ILELCDGLMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 309 GETAYGKYPIEAVQTMTKVAREAEKTkLSANDIRVPIEGNDLDVTSFLAkQAVKS-SSKLHVKAIITDSYTGRTARYLAA 387
Cdd:PRK06354 319 NETAAGDYPVEAVQTMATIAVRIEKD-LPYRDILSKRPEFTTTITNAIS-QAVSHiALQLDAAAIVTLTKSGATARNVSK 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 388 FRGTSTVFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYLSGSF-GEGGGTSFLEIN 466
Cdd:PRK06354 397 YRPKTPILAVTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAGTLvGESGSTDLMKVH 476
|
490
....*....|
gi 1471120868 467 NVGKVLDAGT 476
Cdd:PRK06354 477 VVGAVVAKGQ 486
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
2-460 |
3.49e-137 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 403.67 E-value: 3.49e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 2 LKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHM-MEEGLTRVvNNVRTVSD----RIGILMDTKGPEVRTTTTVN 76
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGdYAEHGQRI-KNLRNVMSktgkKAAILLDTKGPEIRTMKLEG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 77 KEPIPFKTGEIV------KVIGNPDqetshdCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLG 150
Cdd:PRK09206 80 GNDVSLKAGQTFtfttdkSVVGNKE------RVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 151 SRKSVNVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERN-SPIKIIAKIENQEGVDNIEEI 229
Cdd:PRK09206 154 ENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGgENIQIISKIENQEGLNNFDEI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 230 LEVAYGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSG 309
Cdd:PRK09206 234 LEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSG 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 310 ETAYGKYPIEAVQTMTKVAREAEKTKLSANDIRvpIEGNDLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFR 389
Cdd:PRK09206 314 ESAKGKYPLEAVSIMATICERTDRVMNSRLESN--NDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYF 391
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1471120868 390 GTSTVFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYLSGSFGEGGGT 460
Cdd:PRK09206 392 PDATILALTTNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSGALVPSGTT 462
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
2-334 |
2.06e-135 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 394.43 E-value: 2.06e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 2 LKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVN- 76
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKtggtVAIALDTKGPEIRTGNTKDg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 77 KEPIPFKTGEIVKVIGNPDQETSHD--CICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGD-CLLCEIQNDATLGSRK 153
Cdd:pfam00224 81 KKDIELKAGDEMIVSTDAKYKGACDdeMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 154 SVNVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEVA 233
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 234 YGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAY 313
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|.
gi 1471120868 314 GKYPIEAVQTMTKVAREAEKT 334
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEKA 341
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
5-389 |
2.70e-124 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 372.00 E-value: 2.70e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 5 TKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDRIGI----LMDTKGPEVRTTTTVNKEPI 80
Cdd:PLN02461 23 TKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGIlcavMLDTKGPEIRTGFLKDGKPV 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 81 PFKTGEIVKVIGNPDQETSHDCICVSYKNFVNDLAIGSDILIDDGDLEMKV--TGKSGDCLLCEIQNDATLGSRKSVNVP 158
Cdd:PLN02461 103 QLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVlsCDVEAGTVRCRCENSAMLGERKNVNLP 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 159 GVRINLPSLTEKDRNNIL-WAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEVAYGVM 237
Cdd:PLN02461 183 GVVVDLPTLTEKDKEDILqWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLDNFDDILAESDAFM 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 238 IARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYP 317
Cdd:PLN02461 263 VARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAYP 342
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1471120868 318 IEAVQTMTKVAREAEKTkLSANDI------RVPIEgndLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFR 389
Cdd:PLN02461 343 ELAVKTMARICREAEAS-LDYGALfkeimrSAPLP---MSPLESLASSAVRTANKVKASLIVVLTRGGTTARLVAKYR 416
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
1-469 |
6.83e-123 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 367.33 E-value: 6.83e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 1 MLKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVN 76
Cdd:PRK06247 3 RNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDEtgrpIGILADLQGPKLRLGRFAD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 77 KePIPFKTGEIVkVIGNPDQETSHDCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVN 156
Cdd:PRK06247 83 G-KVQLANGQTF-RLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 157 VPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERnspIKIIAKIENQEGVDNIEEILEVAYGV 236
Cdd:PRK06247 161 LPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKIIGGR---VPVMAKIEKPQAIDRLEAIVEASDAI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 237 MIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKY 316
Cdd:PRK06247 238 MVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKY 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 317 PIEAVQTMTKVAREAEKTKLSANDI---RVPIEGNDLDVTSFLAKQAvksSSKLHVKAIITDSYTGRTARYLAAFRGTST 393
Cdd:PRK06247 318 PVEAVRTMARIIRQVERDPTYPPLIhaqRPQPEATKRDAISYAARDI---AERLDLAALVAYTSSGDTALRAARERPPLP 394
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1471120868 394 VFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYLSGS-FGEGGGTSFLEINNVG 469
Cdd:PRK06247 395 ILALTPNPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVpPGTPGSTNMLRIAYIG 471
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
3-463 |
1.49e-121 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 365.24 E-value: 1.49e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 3 KHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSD-----RIGILMDTKGPEVRTTTTVNK 77
Cdd:PTZ00066 38 KKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKarpnaNLGILLDTKGPEIRTGFLKNH 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 78 EPIPFKTGEIVKVIGNPDQETSHDCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNV 157
Cdd:PTZ00066 118 KPITLKEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMNL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 158 PGVRINLPSLTEKDRNNIL-WAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEVAYGV 236
Cdd:PTZ00066 198 PGVKVELPVIGEKDKNDILnFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIPKIENIEGLINFDEILAESDGI 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 237 MIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKY 316
Cdd:PTZ00066 278 MVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGKF 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 317 PIEAVQTMTKVAREAEKT-------KLSANDIRVPIEgndldVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFR 389
Cdd:PTZ00066 358 PVEAVNIMAKICFEAETCidyrvlyHAIHLAVPTPVS-----VQEAVARSAVETAEDINAKLIIALTETGNTARLISKYR 432
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1471120868 390 GTSTVFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYLSGSFGEGGGTSFL 463
Cdd:PTZ00066 433 PSCTILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEVAGSSNL 506
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
3-453 |
4.60e-97 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 304.16 E-value: 4.60e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 3 KHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVN-----NVRTVSDRIGILMDTKGPEVRTTTTvnK 77
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDlvkeyNAQSKDNVIAIMLDTKGPEVRSGDL--P 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 78 EPIPFKTGE-----IVKVIGNPDqetshdCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSR 152
Cdd:PLN02623 188 QPIMLEEGQeftftIKRGVSTED------CVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSR 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 153 KSVNVPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEV 232
Cdd:PLN02623 262 RHLNVRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPNLHSIITA 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 233 AYGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETA 312
Cdd:PLN02623 342 SDGAMVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETA 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 313 YGKYPIEAVQTMTKVAREAEKTkLSANDIrVPIEGNDLD--VTSFLAKQAVKSSSKLHVkAIITDSYTGRTARYLAAFRG 390
Cdd:PLN02623 422 HGKFPLKAVKVMHTVALRTEAT-LPEGTT-PPNLGQAFKnhMSEMFAFHATMMANTLGT-SIIVFTRTGFMAILLSHYRP 498
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1471120868 391 TSTVFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYL-SGS 453
Cdd:PLN02623 499 SGTIFAFTNEKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMVKEGEEVALVqSGR 562
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
29-431 |
3.74e-93 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 290.03 E-value: 3.74e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 29 MNVVRLNTAHMMEEGLTRVVNNVRTVSDR----IGILMDTKGPEVRTTTTVNKEPIpFKTGEIVKVIGNP--DQETSHDC 102
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAElgvnIAIALDTKGPEIRTGLFVGGEAV-MERGATCYVTTDPafADKGTKDK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 103 ICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGD-CLLCEIQNDATLGSRKSVNVPGVRINLPSLTEKDRNNILWAIDH 181
Cdd:PTZ00300 80 FYIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEqTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 182 DLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEVAYGVMIARGDLGIEVPAEKIPGIQRMLIR 261
Cdd:PTZ00300 160 GVDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILIS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 262 KCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPIEAVQTMTKVAREAEKTKLSA--- 338
Cdd:PTZ00300 240 KCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEYvff 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 339 NDIRvPIEGNDLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTSTVFAICYNPRVMRMLGLSYGVWAVhq 418
Cdd:PTZ00300 320 NSIK-KLQPIPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESV-- 396
|
410
....*....|...
gi 1471120868 419 pyndsrrgyFYDA 431
Cdd:PTZ00300 397 ---------FFDA 400
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
21-335 |
3.35e-83 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 261.03 E-value: 3.35e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 21 VEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDRIGILMDTKGPEVRTTTtVNKEPIPFKTGEIVKVIGNPDQETSH 100
Cdd:PRK06739 19 LAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDSIKILGDVQGPKIRLGE-IKGEQITLQAGDSFILHTQPVTGSST 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 101 DCiCVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNVPGVRINLPSLTEKDRNNILWAID 180
Cdd:PRK06739 98 EA-SVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRLPAITEKDKKDIQFLLE 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 181 HDLDFIAHSFVRNKQDVLDIQRILDER--NSPiKIIAKIENQEGVDNIEEILEVAYGVMIARGDLGIEVPAEKIPGIQRM 258
Cdd:PRK06739 177 EDVDFIACSFVRKPSHIKEIRDFIQQYkeTSP-NLIAKIETMEAIENFQDICKEADGIMIARGDLGVELPYQFIPLLQKM 255
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1471120868 259 LIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPIEAVQTMTKVAREAEKTK 335
Cdd:PRK06739 256 MIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVSTLRLVSEFAEHVK 332
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
5-403 |
7.57e-80 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 257.68 E-value: 7.57e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 5 TKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNN----VRTVSDRIGILMDTKGPEVRTtttVNK--E 78
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENlkiaVKNTKKLCAVMLDTVGPELQV---INKteK 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 79 PIPFKTGEIVKVIGNPDQETSHDCICVSYKNFVNDLAIGSDILI--------DDGDLEMKVTGKSGDCLLCEIQNDATL- 149
Cdd:PLN02765 107 PISLKAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFVgqylftgsETTSVWLEVDEVKGDDVVCTVKNSATLa 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 150 GSRKSVNVPGVRINLPSLTEKDRNNI-LWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSP-IKIIAKIENQEGVDNIE 227
Cdd:PLN02765 187 GSLFTLHVSQVRIDLPTLSEKDKEVIsTWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGLSqTQIFAKIENVEGLTHFD 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 228 EILEVAYGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVaTQMLHSMINNPRPTRAEVTDIANAIYYRTDALML 307
Cdd:PLN02765 267 EILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILL 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 308 SGETAYGKYPIEAVQTMTKVAREAEKTKLSANDIR--VPIEGNDLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYL 385
Cdd:PLN02765 346 GAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKktVKYVGEPMSHLESIASSAVRAAIKVKASVIIVFTSSGRAARLI 425
|
410
....*....|....*...
gi 1471120868 386 AAFRGTSTVFAICYnPRV 403
Cdd:PLN02765 426 AKYRPTMPVLSVVI-PRL 442
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
2-451 |
3.99e-74 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 242.34 E-value: 3.99e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 2 LKHTKIVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDRIG----ILMDTKGPEVRT-----T 72
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGfavaVMMDTEGSEIHMgdlggA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 73 TTVNKEPIPFKTGEIVKVIGNPDQETSHdcicVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSR 152
Cdd:PLN02762 104 SSAKAEDGEEWTFTVRKFDGSRPEFTIQ----VNYDGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCKCTDPGLLLPR 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 153 KSVN-------VPGVRINLPSLTEKDRNNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDER--NSPIKIIAKIENQEGV 223
Cdd:PLN02762 180 ANLTfwrdgslVRERNAMLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARsrDSDIGVIAKIESLDSL 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 224 DNIEEILEVAYGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTD 303
Cdd:PLN02762 260 KNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRAD 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 304 ALMLSGETAYGKYPIEAVQTMTKVAREAEK--------TKLSANDIRVPIEGNdldVTSFLAKQAVKSSSKLHVKAIITD 375
Cdd:PLN02762 340 ALMLSGESAMGLYPEKALSVLRSVSLRMELwsreekrhEALELPQLSSSLSDR---ISEEICNSAAKMANNLGVDAIFVY 416
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1471120868 376 SYTGRTARYLAAFRGTSTVFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQLIHSGRITRNDMVAYLS 451
Cdd:PLN02762 417 TKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLDFSDDMESNLNKTFSLLKARGMIKSGDLVIAVS 492
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
3-324 |
3.25e-53 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 186.37 E-value: 3.25e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 3 KHTKIVATV-SDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDRIG----ILMDTKGPEVRTTTTvnK 77
Cdd:PRK08187 133 RRTRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGrrckILMDLAGPKIRTGAV--A 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 78 EPIP---FKTGE---IVKVIGNPDQETSHDCICVSYKNFVNDLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGS 151
Cdd:PRK08187 211 GPLGktrLYTGDrlaLVAQGPPRRIDEEHFQVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEVTHARPKGL 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 152 R----KSVNVPGVRINLPSLTEKDRNnilwaidhDLDFIA-------HSFVRNKQDVLDIQRILDERN----SPIKIIAK 216
Cdd:PRK08187 291 KlkpeKGLNFPDTALDLPALTEKDRA--------DLDFVArhadlvgYSFVQSPGDVEALQAALAARRpddwRKLGLVLK 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 217 IENQEGVDNIEEILEVA-----YGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEV 291
Cdd:PRK08187 363 IETPRAVANLPELIVQAagrqpFGVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEM 442
|
330 340 350
....*....|....*....|....*....|...
gi 1471120868 292 TDIANAiyYRTDALMLSGetayGKYPIEAVQTM 324
Cdd:PRK08187 443 TDAAMA--ARAECVMLNK----GPYLVEAVTFL 469
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
17-329 |
8.69e-41 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 154.34 E-value: 8.69e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 17 DVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVRTVSDRIG----ILMDTKGPEVRT--------------------- 71
Cdd:PRK14725 154 DPDLVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGrrcrIAMDLAGPKLRTgpiapgprviklrptrdalgr 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 72 ------------------------TTTVNKE------------------------------------------------- 78
Cdd:PRK14725 234 vltparlwltasespppspppgpvGLPVDPEwlarlepgdelrftdargkkrkltvtevddegvlaegsqtaylangtll 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 79 -----------PIPFKTGEIVKVIGN---------PDQETSHDC----ICVSYKNFVNDLAIGSDILIDDGDLEMKVTGK 134
Cdd:PRK14725 314 rlgrhdstrvgGLPPVEQKLRLKVGDrlvltrddaPGDPAQGDApparISCTLPEAFRAARVGERVWFDDGKIGAVVVKV 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 135 SGDCLLCEIQNDATLGSR----KSVNVPGVRINLPSLTEKDRNNILWAIDHdLDFIAHSFVRNKQDVLDIQRILDERN-S 209
Cdd:PRK14725 394 EADEVELRITHARPGGSKlkagKGINLPDSHLPLPALTDKDLEDLAFVAKH-ADIVALSFVRSPEDVRLLLDALEKLGaD 472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 210 PIKIIAKIENQEGVDNIEEILEVA-----YGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNP 284
Cdd:PRK14725 473 DLGVVLKIETRRAFENLPRILLEAmrhprFGVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVLESLAKKG 552
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1471120868 285 RPTRAEVTDIANAIyyRTDALMLSGetayGKYPIEAVQTMTKVAR 329
Cdd:PRK14725 553 LPSRAEITDAAMAL--RAECVMLNK----GPHIVEAVRVLDDILR 591
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
262-413 |
1.10e-32 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 126.55 E-value: 1.10e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 262 KCVEVKKPVIVATQMLHSMINNPRPTRAEVTDIANAIYYRTDALMLSGETAYGKYPIEAVQTMTKVAREAEKTKLSANDI 341
Cdd:COG3848 1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQR 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1471120868 342 RVPIEGNDLDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTSTVFAICYNPRVMRMLGLSYGV 413
Cdd:COG3848 81 VPRAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGV 152
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
356-465 |
9.16e-16 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 73.28 E-value: 9.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 356 LAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTSTVFAICYNPRVMRMLGLSYGVWAVHQPYNDSRRGYFYDALNQL 435
Cdd:pfam02887 3 IAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVKVA 82
|
90 100 110
....*....|....*....|....*....|.
gi 1471120868 436 IHSGRITRNDMVAYLSG-SFGEGGGTSFLEI 465
Cdd:pfam02887 83 KEAGLVKKGDLVVITAGvPFGVSGTTNTLKV 113
|
|
| HpcH_HpaI |
pfam03328 |
HpcH/HpaI aldolase/citrate lyase family; This family includes 2,4-dihydroxyhept-2-ene-1, ... |
158-239 |
5.44e-03 |
|
HpcH/HpaI aldolase/citrate lyase family; This family includes 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase and 4-hydroxy-2-oxovalerate aldolase.
Pssm-ID: 427247 [Multi-domain] Cd Length: 221 Bit Score: 38.49 E-value: 5.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471120868 158 PGVRINL--PSLTEKDrnniLWAIDHDLDFIAHSFVRNKQDVLDIQRILDER-------NSPIKIIAKIENQEGVDNIEE 228
Cdd:pfam03328 62 VVVRVNSldSPFGKQD----LAVLDLGAQVVLVPKVETAEDARAAVSAIRYPpkgirraNGNTCLLAQIESALGVLNADE 137
|
90
....*....|.
gi 1471120868 229 ILEVAyGVMIA 239
Cdd:pfam03328 138 IAAVE-GVDGI 147
|
|
| |
