|
Name |
Accession |
Description |
Interval |
E-value |
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
6-474 |
0e+00 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 1034.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 6 VYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDSEDALP 85
Cdd:PRK11933 2 VYLPDAFLTQMREAMPSHLSMDDFIAACQRPLRRSIRVNTLKISVADFLQLMAPYGWTLTPIPWCEEGFWIERDDEDALP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 86 LGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRC 165
Cdd:PRK11933 82 LGNTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIVANEYSASRVKVLHANISRC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 166 GISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYS 245
Cdd:PRK11933 162 GVSNVALTHFDGRVFGAALPETFDAILLDAPCSGEGTVRKDPDALKNWSPESNLEIAATQRELIESAFHALKPGGTLVYS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 246 TCTLNQEENEAVCRWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVG 325
Cdd:PRK11933 242 TCTLNREENQAVCLWLKETYPDAVEFEPLGDLFPGAEKALTEEGFLHVFPQIYDSEGFFVARLRKTASVPRLPAPKYKVG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 326 NFPFSPVKDREAGQIRQAAAGVGLNWDENLRLWQRDKELWLFPVSIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIAL 405
Cdd:PRK11933 322 KFPFTPAKDKEAQEIRQAAASVGLSWPENLRLWQRDKEVWLFPAGIEPLIGKVRFSRIGIKLAETHKKGYRWQHEAVIAL 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1471315597 406 ATPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKL 474
Cdd:PRK11933 402 ASPDNANAFELTPQEAEEWYMGRDIYPQTAPPAGEVIVTYQGQPIGLAKRVGNRLKNSLPRELVRDGKL 470
|
|
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
41-310 |
1.15e-154 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 439.98 E-value: 1.15e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 41 IRVNTLKTSVADFLQLTAPYGWTLtpIPWCEEGFWieRDSEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADgnAPQR 120
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVL--EPTCEEYFF--EVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPR--EDER 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 121 VMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEmFDAILLDAPCSGE 200
Cdd:TIGR00446 75 VLDMAAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLK-FDAILLDAPCSGE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 201 GVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQEENEAVCRWLKETYPDAVEFLPLGDLFPG 280
Cdd:TIGR00446 154 GVIRKDPSRKRNWSEEDIKYCSLLQKELIDAAIDALKPGGVLVYSTCSLEVEENEEVIDYILRKRPDVVEEIIKGDEFFG 233
|
250 260 270
....*....|....*....|....*....|.
gi 1471315597 281 ANKAL-TEEGFLHVFPQIYDCEGFFVARLRK 310
Cdd:TIGR00446 234 INIGKgEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| Ncl1 |
COG3270 |
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and ... |
12-470 |
1.56e-118 |
|
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442501 [Multi-domain] Cd Length: 452 Bit Score: 355.16 E-value: 1.56e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 12 FLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDSEDALPLGSTAE 91
Cdd:COG3270 3 PLLELFQLMMLLLLEEEAAFAAALRLLRRSSLRVLLLKAAEDLALRLLAPPPLLPPPPWPEGGGYEEDEELGGPLGLAAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 92 HLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVA 171
Cdd:COG3270 83 ALYYLQEAAAASSALPVAALPGLLLLLAAAAGGAAATAAAAAQGGLLLNLLNIILALELLASSVEVLHANIVVVVNTNTP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 172 LTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQ 251
Cdd:COG3270 163 LAELAGFVFFDALDADADASLLGGGFPREGAAAKEADPLRKASAEIQLEIEAAAAAALLLGGGALLLTTTTEPSEEEEEE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 252 EENEAVCRWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPfsp 331
Cdd:COG3270 243 EELLLLLEELDLALEPAVEEGAGEGGDPEAAAALTELLGLHRFPPHGEGGGGFFAALKKKAGDEPSPKKKKKKKKPK--- 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 332 vkdrEAGQIRQAAAGVGLNWDENLRLWQRDKELWLFPVSIEALiGKVRFSRLGIKLAETHNKGYRWQHEAVIALATPDNV 411
Cdd:COG3270 320 ----QAKEVLRAFAEEGLPLPEVGRLWERGGKLYLLPEELPDL-SGLKVLRIGLKLGEIKKKRFEPSHALALALGPEATK 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 1471315597 412 NAFELTPQEAEEWYRGRDVYPQAAPvADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVR 470
Cdd:COG3270 395 NVVELDAEEALRYLKGEDIELEDGD-KGWVLVTYDGYPLGWGKYVGGRLKNHYPKGLRR 452
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
119-309 |
1.01e-52 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 176.46 E-value: 1.01e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 119 QRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPE-MFDAILLDAPC 197
Cdd:pfam01189 10 ETILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGvLFDRILLDAPC 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 198 SGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQEENEAVCRWLKETYPDaVEFLPLgDL 277
Cdd:pfam01189 90 SGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIEYFLQKHPD-VELVPT-PL 167
|
170 180 190
....*....|....*....|....*....|..
gi 1471315597 278 FPGANKALTEEGFLHVFPQIYDCEGFFVARLR 309
Cdd:pfam01189 168 FEPVGLAIGEQPTLRLLPHTHNGDGFFIAKLR 199
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
120-245 |
2.01e-03 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 37.79 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 120 RVMDVAAAPGSKTTQIAARmnNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSg 199
Cdd:cd02440 1 RVLDLGCGTGALALALASG--PGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADESFDVIISDPPLH- 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1471315597 200 egvvrkdpdalknWSPESnqeiaatQRELIDSAFHSLRPGGTLVYS 245
Cdd:cd02440 78 -------------HLVED-------LARFLEEARRLLKPGGVLVLT 103
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
6-474 |
0e+00 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 1034.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 6 VYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDSEDALP 85
Cdd:PRK11933 2 VYLPDAFLTQMREAMPSHLSMDDFIAACQRPLRRSIRVNTLKISVADFLQLMAPYGWTLTPIPWCEEGFWIERDDEDALP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 86 LGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRC 165
Cdd:PRK11933 82 LGNTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIVANEYSASRVKVLHANISRC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 166 GISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYS 245
Cdd:PRK11933 162 GVSNVALTHFDGRVFGAALPETFDAILLDAPCSGEGTVRKDPDALKNWSPESNLEIAATQRELIESAFHALKPGGTLVYS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 246 TCTLNQEENEAVCRWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVG 325
Cdd:PRK11933 242 TCTLNREENQAVCLWLKETYPDAVEFEPLGDLFPGAEKALTEEGFLHVFPQIYDSEGFFVARLRKTASVPRLPAPKYKVG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 326 NFPFSPVKDREAGQIRQAAAGVGLNWDENLRLWQRDKELWLFPVSIEALIGKVRFSRLGIKLAETHNKGYRWQHEAVIAL 405
Cdd:PRK11933 322 KFPFTPAKDKEAQEIRQAAASVGLSWPENLRLWQRDKEVWLFPAGIEPLIGKVRFSRIGIKLAETHKKGYRWQHEAVIAL 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1471315597 406 ATPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKL 474
Cdd:PRK11933 402 ASPDNANAFELTPQEAEEWYMGRDIYPQTAPPAGEVIVTYQGQPIGLAKRVGNRLKNSLPRELVRDGKL 470
|
|
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
41-310 |
1.15e-154 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 439.98 E-value: 1.15e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 41 IRVNTLKTSVADFLQLTAPYGWTLtpIPWCEEGFWieRDSEDALPLGSTAEHLSGLFYIQEASSMLPVAALFADgnAPQR 120
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVL--EPTCEEYFF--EVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPR--EDER 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 121 VMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEmFDAILLDAPCSGE 200
Cdd:TIGR00446 75 VLDMAAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLK-FDAILLDAPCSGE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 201 GVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQEENEAVCRWLKETYPDAVEFLPLGDLFPG 280
Cdd:TIGR00446 154 GVIRKDPSRKRNWSEEDIKYCSLLQKELIDAAIDALKPGGVLVYSTCSLEVEENEEVIDYILRKRPDVVEEIIKGDEFFG 233
|
250 260 270
....*....|....*....|....*....|.
gi 1471315597 281 ANKAL-TEEGFLHVFPQIYDCEGFFVARLRK 310
Cdd:TIGR00446 234 INIGKgEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| Ncl1 |
COG3270 |
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and ... |
12-470 |
1.56e-118 |
|
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442501 [Multi-domain] Cd Length: 452 Bit Score: 355.16 E-value: 1.56e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 12 FLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDSEDALPLGSTAE 91
Cdd:COG3270 3 PLLELFQLMMLLLLEEEAAFAAALRLLRRSSLRVLLLKAAEDLALRLLAPPPLLPPPPWPEGGGYEEDEELGGPLGLAAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 92 HLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVA 171
Cdd:COG3270 83 ALYYLQEAAAASSALPVAALPGLLLLLAAAAGGAAATAAAAAQGGLLLNLLNIILALELLASSVEVLHANIVVVVNTNTP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 172 LTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQ 251
Cdd:COG3270 163 LAELAGFVFFDALDADADASLLGGGFPREGAAAKEADPLRKASAEIQLEIEAAAAAALLLGGGALLLTTTTEPSEEEEEE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 252 EENEAVCRWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPfsp 331
Cdd:COG3270 243 EELLLLLEELDLALEPAVEEGAGEGGDPEAAAALTELLGLHRFPPHGEGGGGFFAALKKKAGDEPSPKKKKKKKKPK--- 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 332 vkdrEAGQIRQAAAGVGLNWDENLRLWQRDKELWLFPVSIEALiGKVRFSRLGIKLAETHNKGYRWQHEAVIALATPDNV 411
Cdd:COG3270 320 ----QAKEVLRAFAEEGLPLPEVGRLWERGGKLYLLPEELPDL-SGLKVLRIGLKLGEIKKKRFEPSHALALALGPEATK 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 1471315597 412 NAFELTPQEAEEWYRGRDVYPQAAPvADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVR 470
Cdd:COG3270 395 NVVELDAEEALRYLKGEDIELEDGD-KGWVLVTYDGYPLGWGKYVGGRLKNHYPKGLRR 452
|
|
| RsmB |
COG0144 |
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ... |
8-311 |
4.42e-96 |
|
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 439914 [Multi-domain] Cd Length: 441 Bit Score: 296.92 E-value: 4.42e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 8 FPDAFLTQMREAMPSTlSFDDFLAACQRPLRRSIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIErdseDALPLG 87
Cdd:COG0144 147 HPEWLVERLRAAYGPE-EAEALLAALNEPPPLDLRVNTLKASREELLARLAEEGIEAEPTPLSPDGLRLE----GPGPVT 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 88 STAEHLSGLFYIQEASSMLPVAALfaDGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGI 167
Cdd:COG0144 222 ALPGFREGLFSVQDEASQLVALLL--DPKPGERVLDLCAAPGGKTLHLAELMGNKGRVVAVDISEHRLKRLRENLARLGL 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 168 SNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTC 247
Cdd:COG0144 300 SNVEVVVADARELLEWLPGKFDRVLLDAPCSGTGTLRRHPDIKWRRTPEDIAELAALQRELLDAAARLLKPGGRLVYSTC 379
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1471315597 248 TLNQEENEAVCRWLKETYPDAvEFLPLGDLFPGAnkALTEEGFLHVFPQIYDCEGFFVARLRKT 311
Cdd:COG0144 380 SLLPEENEEVVEAFLARHPDF-ELVPLAELLPGL--ALTDGGYLRLLPHRHGTDGFFIARLRKK 440
|
|
| PRK14902 |
PRK14902 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
40-310 |
1.72e-76 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 237857 [Multi-domain] Cd Length: 444 Bit Score: 246.24 E-value: 1.72e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 40 SIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDSedalpLGSTAEHLSGLFYIQEASSMLPVAALFADGNapQ 119
Cdd:PRK14902 180 SIRVNTLKISVEELIEKLEEEGYEVEESLLSPEALVIEKGN-----IAGTDLFKDGLITIQDESSMLVAPALDPKGG--D 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 120 RVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSG 199
Cdd:PRK14902 253 TVLDACAAPGGKTTHIAELLKNTGKVVALDIHEHKLKLIEENAKRLGLTNIETKALDARKVHEKFAEKFDKILVDAPCSG 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 200 EGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQEENEAVCRWLKETYPDaVEFLPLGDLFP 279
Cdd:PRK14902 333 LGVIRRKPDIKYNKTKEDIESLQEIQLEILESVAQYLKKGGILVYSTCTIEKEENEEVIEAFLEEHPE-FELVPLQHEKP 411
|
250 260 270
....*....|....*....|....*....|.
gi 1471315597 280 GANKALTEEGFLHVFPQIYDCEGFFVARLRK 310
Cdd:PRK14902 412 DELVYEVKDGYLQILPNDYGTDGFFIAKLRK 442
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
119-309 |
1.01e-52 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 176.46 E-value: 1.01e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 119 QRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPE-MFDAILLDAPC 197
Cdd:pfam01189 10 ETILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGvLFDRILLDAPC 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 198 SGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQEENEAVCRWLKETYPDaVEFLPLgDL 277
Cdd:pfam01189 90 SGTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIEYFLQKHPD-VELVPT-PL 167
|
170 180 190
....*....|....*....|....*....|..
gi 1471315597 278 FPGANKALTEEGFLHVFPQIYDCEGFFVARLR 309
Cdd:pfam01189 168 FEPVGLAIGEQPTLRLLPHTHNGDGFFIAKLR 199
|
|
| PRK14901 |
PRK14901 |
16S rRNA methyltransferase B; Provisional |
31-312 |
2.07e-49 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237856 [Multi-domain] Cd Length: 434 Bit Score: 174.73 E-value: 2.07e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 31 AACQRPLRRSIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDSEDALPLGSTAEhlsGLFYIQEASSMLpVAA 110
Cdd:PRK14901 171 KWFNQPPSLDLRINPLRTSLEEVQAALAEAGITATPIPGLPQGLRLTGNPGSIRQLPGYEE---GWWTVQDRSAQL-VAP 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 111 LFAdgnaPQ---RVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPE- 186
Cdd:PRK14901 247 LLD----PQpgeVILDACAAPGGKTTHIAELMGDQGEIWAVDRSASRLKKLQENAQRLGLKSIKILAADSRNLLELKPQw 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 187 --MFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQEENEAVCRWLKET 264
Cdd:PRK14901 323 rgYFDRILLDAPCSGLGTLHRHPDARWRQTPEKIQELAPLQAELLESLAPLLKPGGTLVYATCTLHPAENEAQIEQFLAR 402
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1471315597 265 YPDAveflplgdlfpganKALTEEgfLHVFPQIYDCEGFFVARLRKTQ 312
Cdd:PRK14901 403 HPDW--------------KLEPPK--QKIWPHRQDGDGFFMAVLRKKS 434
|
|
| Methyltr_RsmF_N |
pfam17125 |
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the ... |
9-104 |
6.13e-36 |
|
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the RsmF methyl transferase. RsmF is a multi-site-specific methyltransferase that is responsible for the synthesis of three modifications on cytidines in 16S ribosomal RNA. The N-terminus is critical for stabilising the catalytic core of the enzyme.
Pssm-ID: 465356 [Multi-domain] Cd Length: 88 Bit Score: 127.98 E-value: 6.13e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 9 PDAFLTQMREAMPStlSFDDFLAACQRPLRRSIRVNTLKTSVADFLQLTApygWTLTPIPWCEEGFWIERDSEdalpLGS 88
Cdd:pfam17125 2 PEAFIERMRALLGD--EYEAFLAAYDEPRPVGLRVNTLKISVEEFLKLSP---FELEPVPWCEEGFYLEERPR----PGK 72
|
90
....*....|....*.
gi 1471315597 89 TAEHLSGLFYIQEASS 104
Cdd:pfam17125 73 HPYHHAGLYYIQEPSA 88
|
|
| PRK14903 |
PRK14903 |
16S rRNA methyltransferase B; Provisional |
34-311 |
7.84e-36 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 184896 [Multi-domain] Cd Length: 431 Bit Score: 137.70 E-value: 7.84e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 34 QRPLRRSIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDSEdalPLGSTAEHLSGLFYIQ-EASSMLPvaaLF 112
Cdd:PRK14903 159 QEPLPTMLRVNSLAITREEVIKILAEEGTEAVPGKHSPFSLIVRKLGV---NMNDSRVIKDGLATVQgESSQIVP---LL 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 113 ADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAIL 192
Cdd:PRK14903 233 MELEPGLRVLDTCAAPGGKTTAIAELMKDQGKILAVDISREKIQLVEKHAKRLKLSSIEIKIADAERLTEYVQDTFDRIL 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 193 LDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQEENEAVCRWLKETYPDaVEFL 272
Cdd:PRK14903 313 VDAPCTSLGTARNHPEVLRRVNKEDFKKLSEIQLRIVSQAWKLLEKGGILLYSTCTVTKEENTEVVKRFVYEQKD-AEVI 391
|
250 260 270
....*....|....*....|....*....|....*....
gi 1471315597 273 PLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKT 311
Cdd:PRK14903 392 DIRDKLEEFEVEGIWDGYGFLMLPDETLTPFYVSVLRKM 430
|
|
| rsmB |
TIGR00563 |
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. ... |
8-310 |
2.11e-35 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. The reading frame was originally interpreted as two reading frames, fmu and fmv. The recombinant protein from E. coli was shown to methylate only C967 of small subunit (16S) ribosomal RNA and to produce only m5C at that position. The seed alignment is built from bacterial sequences only. Eukaryotic homologs include Nop2, a protein required for processing pre-rRNA, that is likely also a rRNA methyltransferase, although the fine specificity may differ. Cutoff scores are set to avoid treating archaeal and eukaroytic homologs automatically as functionally equivalent, although they may have very similar roles. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 273141 [Multi-domain] Cd Length: 426 Bit Score: 136.54 E-value: 2.11e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 8 FPDAFLTQMREAMPStlSFDDFLAACQRPLRRSIRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERDSedalPLG 87
Cdd:TIGR00563 137 HPEWLVKRLQKAYPG--QWQSICEANNQRPPMWLRINRTKHSRDEWLALLAEAGMKGFPHDLAPDAVRLETPA----AVH 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 88 STAEHLSGLFYIQEASSMLPVAALfadgnAPQR---VMDVAAAPGSKTTQIAARMNnEGAILANEFSASRVKVLHANISR 164
Cdd:TIGR00563 211 ALPGFEEGWVTVQDASAQWVATWL-----APQNeetILDACAAPGGKTTHILELAP-QAQVVALDIHEHRLKRVYENLKR 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 165 CGISNVALThFDGRVFG---AAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGT 241
Cdd:TIGR00563 285 LGLTIKAET-KDGDGRGpsqWAENEQFDRILLDAPCSATGVIRRHPDIKWLRKPRDIAELAELQSEILDAIWPLLKTGGT 363
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1471315597 242 LVYSTCTLNQEENEAVCRWLKETYPDaveflplgdlFPGANKALTEE---GFLHVFPQIYDCEGFFVARLRK 310
Cdd:TIGR00563 364 LVYATCSVLPEENSEQIKAFLQEHPD----------FPFEKTGTPEQvrdGGLQILPHAEEGDGFFYAKLIK 425
|
|
| PRK10901 |
PRK10901 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
41-310 |
8.57e-35 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 236790 [Multi-domain] Cd Length: 427 Bit Score: 134.55 E-value: 8.57e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 41 IRVNTLKTSVADFLQLTAPYGWTLTPIPWCEEGFWIERdsedALPLGST---AEhlsGLFYIQEASSMLpvAALFADGNA 117
Cdd:PRK10901 174 LRVNRRHHSRDAYLALLAEAGIEAFPHAVGPDAIRLET----PVPVHQLpgfAE---GWVSVQDAAAQL--AATLLAPQN 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 118 PQRVMDVAAAPGSKTTQIAARMNNEGaILANEFSASRVKVLHANISRCGIsNVALTHFDGRVFGAAVP-EMFDAILLDAP 196
Cdd:PRK10901 245 GERVLDACAAPGGKTAHILELAPQAQ-VVALDIDAQRLERVRENLQRLGL-KATVIVGDARDPAQWWDgQPFDRILLDAP 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 197 CSGEGVVRKDPDaLKnW--SPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQEENEAVCRWLKETYPDAVEfLPL 274
Cdd:PRK10901 323 CSATGVIRRHPD-IK-WlrRPEDIAALAALQSEILDALWPLLKPGGTLLYATCSILPEENEQQIKAFLARHPDAEL-LDT 399
|
250 260 270
....*....|....*....|....*....|....*..
gi 1471315597 275 GDLF-PGankalteegfLHVFPQIYDCEGFFVARLRK 310
Cdd:PRK10901 400 GTPQqPG----------RQLLPGEEDGDGFFYALLIK 426
|
|
| PRK14904 |
PRK14904 |
16S rRNA methyltransferase B; Provisional |
30-312 |
1.33e-34 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237858 [Multi-domain] Cd Length: 445 Bit Score: 134.42 E-value: 1.33e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 30 LAACQRPLRRSIRVNTLKTSVADFLQ--LTAPYGWTLTPIPwceeGFWIERDSEDALPLGSTaehlsGLFYIQEASSMLP 107
Cdd:PRK14904 172 LSYNNQAPLFGFRINRLKTTPEKFLAapADASVTFEKSGLP----NFFLSKDFSLFEPFLKL-----GLVSVQNPTQALA 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 108 VaaLFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAavPEM 187
Cdd:PRK14904 243 C--LLLNPQPGSTVLDLCAAPGGKSTFMAELMQNRGQITAVDRYPQKLEKIRSHASALGITIIETIEGDARSFSP--EEQ 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 188 FDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHSLRPGGTLVYSTCTLNQEENE-AVCRWLKEtYP 266
Cdd:PRK14904 319 PDAILLDAPCTGTGVLGRRAELRWKLTPEKLAELVGLQAELLDHAASLLKPGGVLVYATCSIEPEENElQIEAFLQR-HP 397
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1471315597 267 DAVEFLPLGDLFPGANKALTEEGFLHVFPQiyDCEGF---FVARLRKTQ 312
Cdd:PRK14904 398 EFSAEPSPGSLPEPFHEVAHPKGAILTLPG--EHEGFdggFAQRLRKNA 444
|
|
| Methyltranf_PUA |
pfam13636 |
RNA-binding PUA-like domain of methyltransferase RsmF; Methyltranf_PUA is the second of two ... |
421-470 |
1.85e-11 |
|
RNA-binding PUA-like domain of methyltransferase RsmF; Methyltranf_PUA is the second of two C-terminal domains found on bacterial methyltransferase RsmF that modifies the 16S ribosomal RNA. It has some structural similarity to the RNA-binding PUA domains suggesting that it is involved in RNA recognition. It lies downstream of the catalytic centre of this methyltransferase, family pfam01189.
Pssm-ID: 433368 [Multi-domain] Cd Length: 50 Bit Score: 58.69 E-value: 1.85e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1471315597 421 AEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVR 470
Cdd:pfam13636 1 ALRYLRGETIELDGDLKAGWVLVTYDGFPLGWGKLLGGRLKNLYPKGLRI 50
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
120-245 |
2.01e-03 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 37.79 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471315597 120 RVMDVAAAPGSKTTQIAARmnNEGAILANEFSASRVKVLHANISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSg 199
Cdd:cd02440 1 RVLDLGCGTGALALALASG--PGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADESFDVIISDPPLH- 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1471315597 200 egvvrkdpdalknWSPESnqeiaatQRELIDSAFHSLRPGGTLVYS 245
Cdd:cd02440 78 -------------HLVED-------LARFLEEARRLLKPGGVLVLT 103
|
|
| |
