|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
69-694 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 591.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 69 KGKHRVLKWVLGIFFSLIGLGLLAGIAVFAYLYTTT--EVPQPEKFALAEKTTVYYADGTTaIGSYAEQNREIISCEGLP 146
Cdd:COG0744 5 RRGKRLLRRLLGLLLLLLAVLVLAALAGLVALYVADlpDPEELEDLALPQTSTIYDRDGTL-IATLGDENREWVPLDQIP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 147 DYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAERYYMGETTSYVGKAREAIMAIKIAQTES 225
Cdd:COG0744 84 PHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGgVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 226 KDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPADNADMAKSRFKRVLNIMQEDGYI 305
Cdd:COG0744 164 KDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 306 TAKQHTDAKF-PQTAAVAQQNEYAGPNGYLLDMVRRELVQskAFTKEDLDTGGYKIITTIDKSKQDLMQSIGDTRLDD-M 383
Cdd:COG0744 244 TQAEADAAKAePLTLVPPPNGAAAGKYPYFVDYVRRELEE--LLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPEgK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 384 PESLQIGGIALDPKTGEVLSVYAGSDYLSKQLNNADQAVFEPGSTMKPFALLGAAQSGVSFDTLFNGNShQHFTGLDQEV 463
Cdd:COG0744 322 PGGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEQGYTPATTVDDEP-VTFPGGGWSP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 464 NNALENNWGNINLYQATANSVNTVFMNVNEHLTPKRTAAIAHEAGIQGDIDEN-SMynVLGINALTVWDLAQGHSTIANN 542
Cdd:COG0744 401 KNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGITSPLDPNpSL--ALGTSEVSPLEMASAYATFANG 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 543 GVKNTLHMVSKVLDSNNKDMYNAPSNGTKVFDANDCALVQKAMQgTTTYGTAAGTSSMLGRPVAGKSGTANDEMASSFVG 622
Cdd:COG0744 479 GVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQ-DVVTSGTGRAARLPGRPVAGKTGTTNDNRDAWFVG 557
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1471426597 623 YTPSMmnVWAIWNPDDKGNPQvvpafsgYGVSSTGYPAHLFQEFMAQALQGTEAEQFPTAKDNGKIGGSNGT 694
Cdd:COG0744 558 YTPQL--VTAVWVGNDDNSPM-------GYVTGGSLPAPIWRDFMEAALEGLPVEDFPKPSGVVRIDEPSPT 620
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
136-673 |
1.42e-124 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 383.92 E-value: 1.42e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 136 NREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAERYYMGETTSYVGKAREA 214
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGrVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 215 IMAIKIAQTESKDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPADNADMAKSRFKR 294
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 295 VLNIMQEDGYITAKQHTDAK------FPQTaavAQQNEYAGPngYLLDMVRRELVQskaFTKEDLDTGGYKIITTIDKSK 368
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAInepiqlYLQT---KKSEQYKAP--YFVDYVIQELEE---EYGEELYTGGLKIYTTLDLDA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 369 QDLMQSIGDTRLD----DMPESLQIGGIALDPKTGEVLSVYAGSDYLSKQLNNADQAVFEPGSTMKPFALLGAAQSGVSF 444
Cdd:TIGR02074 233 QKAAEKVLNTGLRvagrRDGDDLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEKGLTP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 445 DTLFNGNSHQHFTGLDQEVNNALENNWGNINLYQATANSVNTVFMNVNEHLTPKRTAAIAHEAGIQGDIDEN-SMynVLG 523
Cdd:TIGR02074 313 ATIVNDEPITYNGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLDPVlSL--ALG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 524 INALTVWDLAQGHSTIANNGVKNTLHMVSKVLDSNNKDMYNAPSNGTKVFDANDCALVQKAMQGTTTYGTAAGTSSmLGR 603
Cdd:TIGR02074 391 TVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARL-PGR 469
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 604 PVAGKSGTANDEMASSFVGYTPSMmnVWAIWNPDDKGNPQvvpafsGYGVSSTGYPAHLFQEFMAQALQG 673
Cdd:TIGR02074 470 PVAGKTGTTQNWRDAWFVGYTPYY--VTAVWVGYDDKKTL------GKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
124-300 |
1.63e-75 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 242.43 E-value: 1.63e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 124 DGTTaIGSYAEQNREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAERYYMG 202
Cdd:pfam00912 1 DGTL-LAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGrIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 203 ETTSYVGKAREAIMAIKIAQTESKDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPA 282
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 1471426597 283 DNADMAKSRFKRVLNIMQ 300
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
120-369 |
5.03e-47 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 180.33 E-value: 5.03e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 120 VYYADGTTaIGSYAEQNREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAER 198
Cdd:PRK11636 50 VYSADGEL-IAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGhASQGASTITQQLARN 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 199 YYMGETTSYVGKAREAIMAIKIAQTESKDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPST 278
Cdd:PRK11636 129 FFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPST 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 279 WDPADNADMAKSRFKRVLNIMQEDGYITAKQHTDAKFPQTAAVAQQNEYAGPNGYLLDMVRRELVQSKAftkEDLDTGGY 358
Cdd:PRK11636 209 FNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYG---ENAYEDGY 285
|
250
....*....|.
gi 1471426597 359 KIITTIDKSKQ 369
Cdd:PRK11636 286 RVYTTITRKVQ 296
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
69-694 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 591.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 69 KGKHRVLKWVLGIFFSLIGLGLLAGIAVFAYLYTTT--EVPQPEKFALAEKTTVYYADGTTaIGSYAEQNREIISCEGLP 146
Cdd:COG0744 5 RRGKRLLRRLLGLLLLLLAVLVLAALAGLVALYVADlpDPEELEDLALPQTSTIYDRDGTL-IATLGDENREWVPLDQIP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 147 DYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAERYYMGETTSYVGKAREAIMAIKIAQTES 225
Cdd:COG0744 84 PHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGgVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 226 KDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPADNADMAKSRFKRVLNIMQEDGYI 305
Cdd:COG0744 164 KDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 306 TAKQHTDAKF-PQTAAVAQQNEYAGPNGYLLDMVRRELVQskAFTKEDLDTGGYKIITTIDKSKQDLMQSIGDTRLDD-M 383
Cdd:COG0744 244 TQAEADAAKAePLTLVPPPNGAAAGKYPYFVDYVRRELEE--LLGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPEgK 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 384 PESLQIGGIALDPKTGEVLSVYAGSDYLSKQLNNADQAVFEPGSTMKPFALLGAAQSGVSFDTLFNGNShQHFTGLDQEV 463
Cdd:COG0744 322 PGGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEQGYTPATTVDDEP-VTFPGGGWSP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 464 NNALENNWGNINLYQATANSVNTVFMNVNEHLTPKRTAAIAHEAGIQGDIDEN-SMynVLGINALTVWDLAQGHSTIANN 542
Cdd:COG0744 401 KNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGITSPLDPNpSL--ALGTSEVSPLEMASAYATFANG 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 543 GVKNTLHMVSKVLDSNNKDMYNAPSNGTKVFDANDCALVQKAMQgTTTYGTAAGTSSMLGRPVAGKSGTANDEMASSFVG 622
Cdd:COG0744 479 GVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQ-DVVTSGTGRAARLPGRPVAGKTGTTNDNRDAWFVG 557
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1471426597 623 YTPSMmnVWAIWNPDDKGNPQvvpafsgYGVSSTGYPAHLFQEFMAQALQGTEAEQFPTAKDNGKIGGSNGT 694
Cdd:COG0744 558 YTPQL--VTAVWVGNDDNSPM-------GYVTGGSLPAPIWRDFMEAALEGLPVEDFPKPSGVVRIDEPSPT 620
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
136-673 |
1.42e-124 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 383.92 E-value: 1.42e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 136 NREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAERYYMGETTSYVGKAREA 214
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGrVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 215 IMAIKIAQTESKDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPADNADMAKSRFKR 294
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 295 VLNIMQEDGYITAKQHTDAK------FPQTaavAQQNEYAGPngYLLDMVRRELVQskaFTKEDLDTGGYKIITTIDKSK 368
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAInepiqlYLQT---KKSEQYKAP--YFVDYVIQELEE---EYGEELYTGGLKIYTTLDLDA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 369 QDLMQSIGDTRLD----DMPESLQIGGIALDPKTGEVLSVYAGSDYLSKQLNNADQAVFEPGSTMKPFALLGAAQSGVSF 444
Cdd:TIGR02074 233 QKAAEKVLNTGLRvagrRDGDDLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGSTFKPFVYAAALEKGLTP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 445 DTLFNGNSHQHFTGLDQEVNNALENNWGNINLYQATANSVNTVFMNVNEHLTPKRTAAIAHEAGIQGDIDEN-SMynVLG 523
Cdd:TIGR02074 313 ATIVNDEPITYNGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLDPVlSL--ALG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 524 INALTVWDLAQGHSTIANNGVKNTLHMVSKVLDSNNKDMYNAPSNGTKVFDANDCALVQKAMQGTTTYGTAAGTSSmLGR 603
Cdd:TIGR02074 391 TVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSARL-PGR 469
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 604 PVAGKSGTANDEMASSFVGYTPSMmnVWAIWNPDDKGNPQvvpafsGYGVSSTGYPAHLFQEFMAQALQG 673
Cdd:TIGR02074 470 PVAGKTGTTQNWRDAWFVGYTPYY--VTAVWVGYDDKKTL------GKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
73-680 |
2.23e-114 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 365.25 E-value: 2.23e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 73 RVLKWVLGIFFSLIGLGLLAgiAVFAYLYTTTEVPQPEKFA---LAEKTTVYYADGTTaIGSYAEQNREIISCEGLPDYI 149
Cdd:COG5009 2 RLLKILLILLLLLLLLGALA--VAGLYLYLSPDLPDVETLKdyqPPTPSRVYSADGKL-IAEFGEERRIPVPIEEIPPLL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 150 GNAIVASENRTFYTDKGLDLKGIARAFINNVTKGTR-QGGSTITQQYAERYYMGETTSYVGKAREAIMAIKIAQTESKDE 228
Cdd:COG5009 79 INAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRvQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 229 VLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPADNADMAKSRFKRVLNIMQEDGYITAK 308
Cdd:COG5009 159 ILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 309 QHTDAKFPQTAAVAQQNEYAGPNGYLLDMVRRELVQSkaFTKEDLDTGGYKIITTIDKSKQ------------------- 369
Cdd:COG5009 239 EYEAAKAEPLTARYHGASAEVDAPYFAEMVRRELVER--YGEDALYTGGLKVYTTLDPRLQeaaekalrdgllaydrrhg 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 370 --------DLMQSIGDTRLDDMPES-------------------LQIGG------------------------------- 391
Cdd:COG5009 317 yrgpeahlDLAEEDWDEALAEVPDVgdlrpavvlevddksarvgLRDGEtgtlpleglkwarpyindnrrgpapksasdv 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 392 -----------------------------IALDPKTGEVLSVYAGSDYLSKQLNNADQAVFEPGSTMKPFALLGAAQSGV 442
Cdd:COG5009 397 lkpgdvirvrpvadggwrlrqipevqgalVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFVYAAALDNGY 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 443 SFDTLFNGNSHQHFTGLDQEV---NNALENNWGNINLYQATANSVNTVFMNVNEHLTPKRTAAIAHEAGIQGDIDEN-SM 518
Cdd:COG5009 477 TPATIINDAPIVFDDGGGGGVwrpKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIYSKLPPNlSL 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 519 ynVLGINALTVWDLAQGHSTIANNGVKNTLHMVSKVLDSNNKDMYNApsngTKVFDANDCALVQKAMQGTTTYGTAAGT- 597
Cdd:COG5009 557 --ALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRA----DPARACEDCDAAEWDGAEPRLPDPAEQVi 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 598 --------SSM---------------LGRPVAGKSGTANDEMASSFVGYTPSMmnvwaiwnpddkgnpqVVPAFSGY--- 651
Cdd:COG5009 631 dprtayqmTSMlrgvvqrgtgrraraLGRDIAGKTGTTNDSKDAWFVGFTPDL----------------VAGVWVGFddp 694
|
730 740 750
....*....|....*....|....*....|....*.
gi 1471426597 652 ---GVSSTGypAHL----FQEFMAQALQGTEAEQFP 680
Cdd:COG5009 695 rslGRGETG--GRAalpiWIDFMKAALKDKPEKPFP 728
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
124-300 |
1.63e-75 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 242.43 E-value: 1.63e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 124 DGTTaIGSYAEQNREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAERYYMG 202
Cdd:pfam00912 1 DGTL-LAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGrIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 203 ETTSYVGKAREAIMAIKIAQTESKDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPA 282
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 1471426597 283 DNADMAKSRFKRVLNIMQ 300
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
71-645 |
3.86e-54 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 200.44 E-value: 3.86e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 71 KHRVLKWVLgiffsLIGLGLLAGIAVFAYLYtttevPQPEKFALAEKTTVYYADGTTAigsyaeqnREIISCEGL----- 145
Cdd:COG4953 7 RRRRLLALL-----LALLLLALALWALDRLF-----PLPLLFAVPYSTVVLDRDGTLL--------RAFLAADGQwrlpv 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 146 ------PDYIgNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYA------ERyymgettSYVGKAR 212
Cdd:COG4953 69 pldevsPRYL-QALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGrIVSGGSTLTMQVArlleprPR-------TLSGKLR 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 213 EAIMAIKIAQTESKDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAgIIP-SPSTWDPADNADMAKSR 291
Cdd:COG4953 141 QILRALQLERRYSKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLA-VLPqAPSRRRPDRNPERARAA 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 292 FKRVLNIMQEDGYITAKQHTDAK----------FPQTAAvaqqneyagpngYLLDMVRRELVQSKaftkedldtggyKII 361
Cdd:COG4953 220 RDRVLARLAEAGVIDAEEAALALlepvparrrpLPQLAP------------HLARRLLRQLPGGT------------RIR 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 362 TTIDKSKQDLMQSIGDTRLddmpESLQIGGI------ALDPKTGEVLSvYAGS-DYLSKQL---NNADQAVFEPGSTMKP 431
Cdd:COG4953 276 TTLDAGLQRRLERLVRRYV----RRLKQNGIhnaavlVVDNRTGEVLA-YVGSaDFFDASRqgqVDMVRALRSPGSTLKP 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 432 FaLLGAAqsgvsFD-------TL-------FNG----NSHQHFTGLdqevnnalennwgnINLYQATANSVNTVFMNVNE 493
Cdd:COG4953 351 F-LYGLA-----LDqglihpeTLladvptsFGGyrpeNFDGTFQGP--------------VSAREALARSLNIPAVRLLE 410
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 494 HLTPKRTAAIAHEAGIQGDIDENSMYN---VLGINALTVWDLAQGHSTIANNGVKNTLHMVSKvldsnnkdmyNAPSNGT 570
Cdd:COG4953 411 ALGPARFYARLRRAGLRLLLPPAEHYGlslILGGAEVTLEELVGLYAALARGGEARPLRLLAG----------EPASPGR 480
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 571 KVFDANDCALVQKAM-QGTTTYGTAAGTSSMLGRPVAGKSGTandemasSF-------VGYTPSmmNVWAIW--NPDDKG 640
Cdd:COG4953 481 RLLSPGAAWLVRDILsDVPRPDGAFGWRALDSPPPIAWKTGT-------SYgfrdawaVGFTGR--YTVGVWvgNPDGTP 551
|
....*
gi 1471426597 641 NPQVV 645
Cdd:COG4953 552 VPGLT 556
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
107-693 |
8.96e-50 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 187.24 E-value: 8.96e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 107 PQPEKFALAEKTTVYYADGT--TAIGSYAEQNREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG- 183
Cdd:TIGR02073 1 PPPLLFHRPSSTVVLDRHGTllRALLANDGQWRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 184 TRQGGSTITQQYAERYYMGETTSYVGKAREAIMAIKIAQTESKDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTL 263
Cdd:TIGR02073 81 RVSGGSTLTMQLARLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 264 SEAAMIAGIIPSPSTWDPADNADMAKSRFKRVLNIMQEDGYITAKQHTDAKFPQTAAVAQQNEYAGPngYLLDMVRRELV 343
Cdd:TIGR02073 161 AEAALLAALPQAPSARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLPALPEPLPQLAP--HFALKLLRARP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 344 QSKAftkedldtggyKIITTIDKSKQDLMQSIGDTRLDDMPES--LQIGGIALDPKTGEVLSvYAGS-DYLSKQLN---N 417
Cdd:TIGR02073 239 EIAS-----------VIVSTLDADLQRRLEELARRYLSALRPRgiSNLAILVVDNRSGAVLA-YVGSaDFFDDSNSgqvD 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 418 ADQAVFEPGSTMKPFaLLGAA--QSGVSFDTL-------FNGNSHQHFTGLDQevnnalennwGNINLYQATANSVNTVF 488
Cdd:TIGR02073 307 GVRAPRSPGSTLKPF-LYALAldDGLLHPDSLlkdvplrFGDYAPENFDKTFH----------GPVPAREALARSLNIPA 375
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 489 MNVNEHLTPKRTAAIAHEAGIQGDIDENSMYN---VLGINALTVWDLAQGHSTIANNGVKNTLHMVSKVLdsnnkdmynA 565
Cdd:TIGR02073 376 VRLLERVGPPRFADFLRQAGLNLLKPKSDYYGlslALGGAEITLQDLANLYAMLANQGLSGPLRFLQTDA---------K 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 566 PSNGTKVFDANDCALVQKAMQGTTTYGTAAGTSSMLGR-PVAGKSGTANDEMASSFVGYTPSMmnVWAIW--NPDDKGNp 642
Cdd:TIGR02073 447 RPERERLLSPGAAWIVLDILKDRPRPDDTLPLSALPTRlPLAWKTGTSYGFRDAWAAGVSGRY--TIGVWvgNFDGKPN- 523
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 1471426597 643 qvvPAFSGYGVSstgypAHLFQEfMAQALQGTEAEQFPTAKDNGKIGGSNG 693
Cdd:TIGR02073 524 ---PGFFGAAAA-----APLLFD-ILDALQASEASTLPRPLKEVPGCLVLG 565
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
120-369 |
5.03e-47 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 180.33 E-value: 5.03e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 120 VYYADGTTaIGSYAEQNREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAER 198
Cdd:PRK11636 50 VYSADGEL-IAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGhASQGASTITQQLARN 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 199 YYMGETTSYVGKAREAIMAIKIAQTESKDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPST 278
Cdd:PRK11636 129 FFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPST 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 279 WDPADNADMAKSRFKRVLNIMQEDGYITAKQHTDAKFPQTAAVAQQNEYAGPNGYLLDMVRRELVQSKAftkEDLDTGGY 358
Cdd:PRK11636 209 FNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVANYHAPEIAFSAPYLSEMVRQEMYNRYG---ENAYEDGY 285
|
250
....*....|.
gi 1471426597 359 KIITTIDKSKQ 369
Cdd:PRK11636 286 RVYTTITRKVQ 296
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
135-622 |
6.89e-40 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 158.39 E-value: 6.89e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 135 QNREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAERYYMGETTSYVGKARE 213
Cdd:PRK09506 209 EQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGrTVQGGSTLTQQLVKNLFLSNERSLWRKANE 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 214 AIMAIKIAQTESKDEVLCNYMNTIYLGRNS----YGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPADNADMAK 289
Cdd:PRK09506 289 AYMALIMDARYSKDRILELYLNEVYLGQSGddqiRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLAL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 290 SRFKRVLNIMQEDGYITAKQHtDAKFPQTAAVAQQNEYAGPNGYLLDMVRRELvQSKAFTKEDlDTGGYKIITTIDKSKQ 369
Cdd:PRK09506 369 ERRNLVLRLLQQQQIIDQELY-DMLSARPLGVQPKGGVISPQPAFMQMVRQEL-QAKLGDKVK-DLSGVKIFTTLDPVSQ 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 370 D-----LMQSIGDTRLDDMPESLQIGGIALDPKTGEVLSVYAGSDYLSKQLNNADQAVFEPGSTMKPFALLGAaqsgvsf 444
Cdd:PRK09506 446 DaaekaVEEGIPALKKQRKLSDLETAMVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTA------- 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 445 dtLFNGNSHQHFTGL-DQEVNNALENN--W----------GNINLYQATANSVNTVFMNVNEHLTPKRTAAIAHEAGIQG 511
Cdd:PRK09506 519 --LSQPDKYRLNTWIaDAPISLRQPNGqvWspqnddrrfsGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPK 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 512 DIDENSMYNVLGINALTVWDLAQGHSTIANNGVKNTLHMVSKVLDSNNKDMYNAPSNGTKVFDANDCALVQKAMQGTTTY 591
Cdd:PRK09506 597 DQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQR 676
|
490 500 510
....*....|....*....|....*....|..
gi 1471426597 592 GTAAGTSSMLGR-PVAGKSGTANDEMASSFVG 622
Cdd:PRK09506 677 GTGRQLGAKYPNlHLAGKTGTTNDLVDSWFAG 708
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
135-622 |
7.95e-36 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 145.37 E-value: 7.95e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 135 QNREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAERYYMGETTSYVGKARE 213
Cdd:PRK14850 155 KKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGhTIQGGSTLTQQLVKNLFLTNTRSLWRKINE 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 214 AIMAIKIAQTESKDEVLCNYMNTIYLGRNS----YGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPADNADMAK 289
Cdd:PRK14850 235 IYMALILDRFYSKDRILELYLNEVYLGQDGneqiRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTL 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 290 SRFKRVLNIMQEDGYITAKQHTDAKfPQTAAVAQQNEYAGPNGYLLDMVRRELVQSKAFTKEDLDtgGYKIITTIDKSKQ 369
Cdd:PRK14850 315 KRRNLVLFLLYKQKVITRKLYKDLC-SRPLNVQSKGNIISSHPAFIQLVCEEFHKKIHYPFKNFS--GTKIFTTLDYISQ 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 370 DLMQS---IGDTRLDDM--PESLQIGGIALDPKTGEVLSVYAGSDYLSKQLNNADQAVFEPGSTMKPFALLGAaqsgVSF 444
Cdd:PRK14850 392 NAAEQavkIGIPILKRKkrLKDLEVAMVIIDRFSGEVRALIGSSKPEFNGYNRALKARRSIGSLSKPITYLTA----LSQ 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 445 DTLFNGNSHQHFTGLDQEVNNAL-----ENNW---GNINLYQATANSVNTVFMNVNEHLTPKRTAaiahEAGIQGDIDEN 516
Cdd:PRK14850 468 PEKYHLNTWISDTPISIKLDNGQywtpkNNNFsfsGKVMLIDALIHSINIPTVHLSINLGLKKLV----DSWILLGISSN 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 517 SMYN----VLGINALTVWDLAQGHSTIANNGVKNTLHMVSKVLDSNNKDMYNAPSNGTKVFDANDCALVQKAMQGTTTYG 592
Cdd:PRK14850 544 YITPlpsiSLGAINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSG 623
|
490 500 510
....*....|....*....|....*....|.
gi 1471426597 593 TAAGTSSMLGR-PVAGKSGTANDEMASSFVG 622
Cdd:PRK14850 624 TAKSLGTIFKEfSLAGKTGTTNNLVDSWFVG 654
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
134-313 |
1.99e-34 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 131.46 E-value: 1.99e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 134 EQNREIISCEGLPDYIGNAIVASENRTFYTDKGLDLKGIARAFINNVTKGTRQGGSTITQQYAERYYMGETTSYVGKARE 213
Cdd:PRK13481 42 ENKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNERSFTRKVKE 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 214 AIMAIKIAQTESKDEVLCNYMNTIYLGRNSYGIQAAAKAYF----NKDAKDL---TLSEAAMIAGIIPSPSTWDPADNAD 286
Cdd:PRK13481 122 LFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFgttvNKNSTTMshiTVLQSAILASKVNAPSVYNINDMSE 201
|
170 180
....*....|....*....|....*..
gi 1471426597 287 MAKSRFKRVLNIMQEDGYITAKQHTDA 313
Cdd:PRK13481 202 NFTQRVSTNLEKMKQQNYINETQYQQA 228
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
357-673 |
2.08e-31 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 129.94 E-value: 2.08e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 357 GYKIITTIDKSkqdlMQSIGDTRLDDMPESLQI---GGIALDPKTGEVL----------SVYagSDYLSKQLNN-ADQAV 422
Cdd:COG0768 218 GKDLVLTIDSD----LQKIAEEALKKAVEEYKAksgAVVVMDPKTGEILamasypsfdpNLF--VGGPDEPLRNrAVQGT 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 423 FEPGSTMKPFALLGAAQSGV-SFDTLFNGNSHQHFTGldQEVNNALENNWGNINLYQATANSVNTVFMNVNEHLTPKRTA 501
Cdd:COG0768 292 YEPGSTFKPFTAAAALEEGViTPDTTFDCPGYYRVGG--RTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLY 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 502 AIAHEAGI------------QGDI-DENSMYNV----LGI---NALTVWDLAQGHSTIANNGVKNTLHMVSKVLDSNNKD 561
Cdd:COG0768 370 DYLKKFGLgqktgidlpgeaSGLLpSPKRWYPGetatMSIgqgLSVTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGEV 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 562 MYNAPSNGTKVFDANDCALVQKAMQGTTTYGT-AAGTSSMLGRPVAGKSGTA-----------NDEMASSFVGYTPSmmn 629
Cdd:COG0768 450 VKEEPEVLRRVISPETAETVREGMEGVVNEPGgTARRAAIPGYRVAGKTGTAqvvdignggyyKGRHIASFVGFAPA--- 526
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1471426597 630 vwaiwnpDdkgNPQVV-------PAFSGYGvSSTGYPahLFQEFMAQALQG 673
Cdd:COG0768 527 -------D---NPRYAvavvvenPGGGAYG-GTVAAP--VFREIMEAYLRL 564
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
392-633 |
1.02e-23 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 102.11 E-value: 1.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 392 IALDPKTGEVLSVYAGSDYLSKQLNNAD-----QAVFEPGSTMKPFALLGAAQSGV-SFDTLFNgnsHQHFT-GLDQEVN 464
Cdd:pfam00905 4 VVLDPKTGEVLAMVGKPSYDPNGFIGPLrnravTSRYEPGSTFKPFTALAALDNGVlKPDETIF---DWPGKqQGGKSIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 465 NALENNWGNINLYQATANSVNTVFMNVNEHLTPKRTAAIAHEAGI-----QGDIDENSMYNV--------------LGIN 525
Cdd:pfam00905 81 DWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgnktgIGLPGENAGYLTpywlegatasfgigLTIT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 526 ALTvwdLAQGHSTIANNGVKNTLHMVSKVLDSNNKDMYNAPsngtkVFDANDCALVQKAMQGTTTYGTAAGTSSMLGRPV 605
Cdd:pfam00905 161 PLQ---QAQAYAAIANGGKLVPPHLVKSIEDKVDPKVLNKL-----PISKSTAEKVKDMLRLVVNDGTGTGTAAVPGYKV 232
|
250 260 270
....*....|....*....|....*....|....*....
gi 1471426597 606 AGKSGTA-----------NDEMASSFVGYTPSMMNVWAI 633
Cdd:pfam00905 233 AGKTGTAqvagpkgggyyDGAQIGWFVGYAPADNPKYAF 271
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
71-432 |
2.98e-15 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 80.13 E-value: 2.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 71 KHRVLKWVLGIFFSLIGLGLLAGIAVFAYLYtttEVpQPEKFALAEKTTVYY----ADGttaIGSYAEQNREIIsceglP 146
Cdd:PRK11240 5 KRGRWLWLAAAPLLLFLALWLADKLWPLPLH---EV-NPARVVVAEDGTPLWrfadADG---IWRYPVTIEDVS-----P 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 147 DYIgNAIVASENRTFYTDKGLDLKGIARAFINNVTKG-TRQGGSTITQQYAeRYYMGETTSYVGKAREAIMAIKIAQTES 225
Cdd:PRK11240 73 RYL-EALINYEDRWFWKHPGVNPFSVARAAWQDLTSGrVISGGSTLTMQVA-RLLDPHPRTFGGKIRQLWRALQLEWHLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 226 KDEVLCNYMNTIYLGRNSYGIQAAAKAYFNKDAKDLTLSEAAMIAGIIPSPSTWDPADNADMAKSRFKRVLNIMQEDGYI 305
Cdd:PRK11240 151 KREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLERMAEQGVW 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 306 TAKQHTDAK----------FPQTAAVaqqneyagpngylldMVRRELVQSKAftkedldtggYKIITTIDKSKQdlmqsi 375
Cdd:PRK11240 231 SAEQVKESReepvwlaprqMPQLAPL---------------FARMMLGKSKS----------DKIVTTLDAGLQ------ 279
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1471426597 376 gdTRLDDM--------PESLQIGGIALDPKTGEVLSvYAGSDYLS--KQLNNAD--QAVFEPGSTMKPF 432
Cdd:PRK11240 280 --RRLEDLalnwkgrlPPRSSLAMIVVDHTDMAVRG-WVGSVDLNddSRFGHVDmvNAIRSPGSVLKPF 345
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
357-625 |
1.02e-12 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 71.40 E-value: 1.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 357 GYKIITTIDKSKQDLMQSigdtRLDDmpeslQIGGI-ALDPKTGEVLSVY--------------AGSDYlsKQLNN---- 417
Cdd:TIGR03423 225 GKDLVLTIDARLQQAAEK----ALGG-----RRGAVvVMDPRTGEILAMVstpsfdpnlfvdgiSSKDY--KALLNdpdr 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 418 -----ADQAVFEPGSTMKPFALLGAAQSGV-SFDTLFNGNSHqhFtgldqEVNNALENNW-----GNINLYQATANSVNT 486
Cdd:TIGR03423 294 pllnrAIQGVYPPGSTFKPVVALAALEEGViTPETRIYCPGY--F-----QLGGRRFRCWkrgghGRVDLRKAIEESCDV 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 487 VFMNVNEHLTPKRTAAIAHEAGIqG-----DIDENSMYNV---------------------LGI----NALTVWDLAQGH 536
Cdd:TIGR03423 367 YFYQLALRLGIDKIAEYAKRFGF-GqktgiDLPGEKSGLVpsrewkrkrfgqpwypgdtlnVSIgqgyVLVTPLQLAVAT 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 537 STIANNGVKNTLHMVSKVLDSNNKDM-YNAPSNGTKV-FDANDCALVQKAMQGTTTYGTAAGTSSMLGRPV--AGKSGTA 612
Cdd:TIGR03423 446 AALANGGKLYKPHLVKSIEDPDGGVVrRTEPEVLRPLpISPENLDVVREGMRDVVNGPGGTARRARLGLPYkmAGKTGTA 525
|
330 340 350
....*....|....*....|....*....|.
gi 1471426597 613 ------------NDEMA------SSFVGYTP 625
Cdd:TIGR03423 526 qvvslkqgekydAEQIPerlrdhALFVAFAP 556
|
|
| PRK15105 |
PRK15105 |
peptidoglycan synthase FtsI; Provisional |
392-442 |
4.94e-03 |
|
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain] Cd Length: 578 Bit Score: 40.19 E-value: 4.94e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1471426597 392 IALDPKTGEVLSVYAGSDYLSKQL---------NNADQAVFEPGSTMKPFALLGAAQSGV 442
Cdd:PRK15105 262 VLVDVNTGEVLAMANSPSYNPNNLsgtpkdamrNRAITDVFEPGSTVKPMVVMTALQRGV 321
|
|
| |
