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Conserved domains on  [gi|1481397649|gb|RJG65716|]
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acetyl-CoA carboxylase carboxyl transferase subunit alpha [Streptococcus pyogenes]

Protein Classification

acetyl-CoA carboxylase carboxyltransferase subunit alpha( domain architecture ID 10013922)

acetyl-CoA carboxylase carboxyltransferase subunit alpha (AccA) is a component of the acetyl coenzyme A carboxylase (ACC) complex that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12319 PRK12319
acetyl-CoA carboxylase subunit alpha; Provisional
 1-256 0e+00

acetyl-CoA carboxylase subunit alpha; Provisional


:

Pssm-ID: 183435 [Multi-domain]  Cd Length: 256  Bit Score: 502.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649   1 MTDVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPN 80
Cdd:PRK12319    1 MTDVARILKEARDQGRLTTLDYATLIFDDFMELHGDRHFRDDGAVVGGIGYLAGQPVTVVGIQKGKNLQDNLKRNFGQPH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  81 PEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ 160
Cdd:PRK12319   81 PEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 161 VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYFSSEIVDIIKANLIEQITSLQAK 240
Cdd:PRK12319  161 VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELLEMGVVDKVIPEHGYFSSEIIDMIKKNLIEELAQLSQK 240

                         250
                  ....*....|....*.
gi 1481397649 241 PLDQLLDERYQRFRKY 256
Cdd:PRK12319  241 PLEQLLEERYQRFRKY 256
 
Name Accession Description Interval E-value
PRK12319 PRK12319
acetyl-CoA carboxylase subunit alpha; Provisional
 1-256 0e+00

acetyl-CoA carboxylase subunit alpha; Provisional


Pssm-ID: 183435 [Multi-domain]  Cd Length: 256  Bit Score: 502.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649   1 MTDVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPN 80
Cdd:PRK12319    1 MTDVARILKEARDQGRLTTLDYATLIFDDFMELHGDRHFRDDGAVVGGIGYLAGQPVTVVGIQKGKNLQDNLKRNFGQPH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  81 PEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ 160
Cdd:PRK12319   81 PEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 161 VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYFSSEIVDIIKANLIEQITSLQAK 240
Cdd:PRK12319  161 VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELLEMGVVDKVIPEHGYFSSEIIDMIKKNLIEELAQLSQK 240

                         250
                  ....*....|....*.
gi 1481397649 241 PLDQLLDERYQRFRKY 256
Cdd:PRK12319  241 PLEQLLEERYQRFRKY 256
AccA COG0825
Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase ...
 11-256 2.26e-141

Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase alpha subunit is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440587 [Multi-domain]  Cd Length: 315  Bit Score: 399.03  E-value: 2.26e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  11 ARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRL 90
Cdd:COG0825    61 ARHPQRPYTLDYIEAIFTDFIELHGDRAFGDDPAIVGGLARFDGRPVMVIGHQKGRDTKERIKRNFGMPHPEGYRKALRL 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  91 MKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPiiaiiigeggsggALALAVADQVWMLENTMYA 170
Cdd:COG0825   141 MKLAEKFGLPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLKVPiisvvigeggsggALAIGVGDRVLMLEHSIYS 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 171 VLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPE-----HgYFSSEIVDIIKANLIEQITSLQAKPLDQL 245
Cdd:COG0825   221 VISPEGCASILWKDASKAPEAAEALKITAQDLKELGIIDEIIPEplggaH-RDPEAAAENLKEALLKALKELKGLSPEEL 299

                         250
                  ....*....|.
gi 1481397649 246 LDERYQRFRKY 256
Cdd:COG0825   300 LEQRYEKFRAI 310
AccA_sub NF041504
carboxyltransferase subunit alpha;
8-255 2.69e-127

carboxyltransferase subunit alpha;


Pssm-ID: 469391 [Multi-domain]  Cd Length: 257  Bit Score: 361.00  E-value: 2.69e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649   8 LKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKA 87
Cdd:NF041504    4 VQVARHPDRPHALDYIAALFTDFTELHGDRLFGDDPAIVGGLGRFRGRPVTVIGQEKGSDTEERLRHNFGMARPEGYRKA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  88 LRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENT 167
Cdd:NF041504   84 LRLMELAEKFGRPVITLIDTPGAYPGVGAEERGQAEAIARSIEAMLQLTVPNIAVIIGEGGSGGALALANANRVLMLEHA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 168 MYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYFSS----EIVDIIKANLIEQITSLQAKPLD 243
Cdd:NF041504  164 IYSVISPEGCASILWRDASRAQEAAEALKLTAQDLLKLGLIDQIIPEPLGGAHrdpaALIAALGDAIEEALAELAGLSAD 243

                         250
                  ....*....|..
gi 1481397649 244 QLLDERYQRFRK 255
Cdd:NF041504  244 ELIAQRREKFLA 255
accA TIGR00513
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; The enzyme acetyl-CoA carboxylase ...
 3-256 6.39e-105

acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; The enzyme acetyl-CoA carboxylase contains a biotin carboxyl carrier protein or domain, a biotin carboxylase, and a carboxyl transferase. This model represents the alpha chain of the carboxyl transferase for cases in which the architecture of the protein is as in E. coli, in which the carboxyltransferase portion consists of two non-identical subnits, alpha and beta. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 273113 [Multi-domain]  Cd Length: 316  Bit Score: 306.73  E-value: 6.39e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649   3 DVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPE 82
Cdd:TIGR00513  56 GAWQRLQLARHPDRPYTLDYIELIFDDFFELAGDRAYADDKAIVGGIARLDGRPVVVIGHQKGRDTKEKLRRNFGMPAPE 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  83 GYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVW 162
Cdd:TIGR00513 136 GYRKALRLMKMAERFKMPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLGVPVICTVIGEGGSGGALAIGVGDKVN 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 163 MLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPE------HGYFSseIVDIIKANLIEQITS 236
Cdd:TIGR00513 216 MLEYSTYSVISPEGCAAILWKDASKAPKAAEAMKITAPDLKELGLIDSIIPEplggahRNPLA--AAASLKEQLLADLAT 293

                         250       260
                  ....*....|....*....|
gi 1481397649 237 LQAKPLDQLLDERYQRFRKY 256
Cdd:TIGR00513 294 LDQLSTEELKNRRYQKLMSL 313
ACCA pfam03255
Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Acetyl co-enzyme A ...
 11-95 4.82e-54

Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Acetyl co-enzyme A carboxylase carboxyltransferase is composed of an alpha and beta subunit.


Pssm-ID: 427221 [Multi-domain]  Cd Length: 144  Bit Score: 171.05  E-value: 4.82e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  11 ARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRL 90
Cdd:pfam03255  60 ARHPERPYTLDYIEALFDDFIELHGDRLFGDDPAIVGGLARFDGQPVMVIGHQKGRDTKENIKRNFGMPHPEGYRKALRL 139


                  ....*
gi 1481397649  91 MKQAE 95
Cdd:pfam03255 140 MKLAE 144
 
Name Accession Description Interval E-value
PRK12319 PRK12319
acetyl-CoA carboxylase subunit alpha; Provisional
 1-256 0e+00

acetyl-CoA carboxylase subunit alpha; Provisional


Pssm-ID: 183435 [Multi-domain]  Cd Length: 256  Bit Score: 502.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649   1 MTDVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPN 80
Cdd:PRK12319    1 MTDVARILKEARDQGRLTTLDYATLIFDDFMELHGDRHFRDDGAVVGGIGYLAGQPVTVVGIQKGKNLQDNLKRNFGQPH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  81 PEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ 160
Cdd:PRK12319   81 PEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 161 VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYFSSEIVDIIKANLIEQITSLQAK 240
Cdd:PRK12319  161 VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELLEMGVVDKVIPEHGYFSSEIIDMIKKNLIEELAQLSQK 240

                         250
                  ....*....|....*.
gi 1481397649 241 PLDQLLDERYQRFRKY 256
Cdd:PRK12319  241 PLEQLLEERYQRFRKY 256
AccA COG0825
Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase ...
 11-256 2.26e-141

Acetyl-CoA carboxylase alpha subunit [Lipid transport and metabolism]; Acetyl-CoA carboxylase alpha subunit is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440587 [Multi-domain]  Cd Length: 315  Bit Score: 399.03  E-value: 2.26e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  11 ARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRL 90
Cdd:COG0825    61 ARHPQRPYTLDYIEAIFTDFIELHGDRAFGDDPAIVGGLARFDGRPVMVIGHQKGRDTKERIKRNFGMPHPEGYRKALRL 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  91 MKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPiiaiiigeggsggALALAVADQVWMLENTMYA 170
Cdd:COG0825   141 MKLAEKFGLPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLKVPiisvvigeggsggALAIGVGDRVLMLEHSIYS 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 171 VLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPE-----HgYFSSEIVDIIKANLIEQITSLQAKPLDQL 245
Cdd:COG0825   221 VISPEGCASILWKDASKAPEAAEALKITAQDLKELGIIDEIIPEplggaH-RDPEAAAENLKEALLKALKELKGLSPEEL 299

                         250
                  ....*....|.
gi 1481397649 246 LDERYQRFRKY 256
Cdd:COG0825   300 LEQRYEKFRAI 310
PRK05724 PRK05724
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated
 11-256 5.41e-133

acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated


Pssm-ID: 235580 [Multi-domain]  Cd Length: 319  Bit Score: 377.95  E-value: 5.41e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  11 ARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRL 90
Cdd:PRK05724   64 ARHPQRPYTLDYIELLFTDFTELHGDRAFADDKAIVGGLARLNGRPVMVIGHQKGRDTKEKIRRNFGMPRPEGYRKALRL 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  91 MKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENTMYA 170
Cdd:PRK05724  144 MKMAEKFGLPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLKVPIICTVIGEGGSGGALAIGVGDRVLMLEYSTYS 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 171 VLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPE-----HgYFSSEIVDIIKANLIEQITSLQAKPLDQL 245
Cdd:PRK05724  224 VISPEGCASILWKDASKAPEAAEAMKITAQDLKELGIIDEIIPEplggaH-RDPEAAAAALKEALLEALAELKGLSPEEL 302

                         250
                  ....*....|.
gi 1481397649 246 LDERYQRFRKY 256
Cdd:PRK05724  303 LERRYEKFMSI 313
AccA_sub NF041504
carboxyltransferase subunit alpha;
8-255 2.69e-127

carboxyltransferase subunit alpha;


Pssm-ID: 469391 [Multi-domain]  Cd Length: 257  Bit Score: 361.00  E-value: 2.69e-127
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649   8 LKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKA 87
Cdd:NF041504    4 VQVARHPDRPHALDYIAALFTDFTELHGDRLFGDDPAIVGGLGRFRGRPVTVIGQEKGSDTEERLRHNFGMARPEGYRKA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  88 LRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENT 167
Cdd:NF041504   84 LRLMELAEKFGRPVITLIDTPGAYPGVGAEERGQAEAIARSIEAMLQLTVPNIAVIIGEGGSGGALALANANRVLMLEHA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 168 MYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYFSS----EIVDIIKANLIEQITSLQAKPLD 243
Cdd:NF041504  164 IYSVISPEGCASILWRDASRAQEAAEALKLTAQDLLKLGLIDQIIPEPLGGAHrdpaALIAALGDAIEEALAELAGLSAD 243

                         250
                  ....*....|..
gi 1481397649 244 QLLDERYQRFRK 255
Cdd:NF041504  244 ELIAQRREKFLA 255
accA TIGR00513
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; The enzyme acetyl-CoA carboxylase ...
 3-256 6.39e-105

acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; The enzyme acetyl-CoA carboxylase contains a biotin carboxyl carrier protein or domain, a biotin carboxylase, and a carboxyl transferase. This model represents the alpha chain of the carboxyl transferase for cases in which the architecture of the protein is as in E. coli, in which the carboxyltransferase portion consists of two non-identical subnits, alpha and beta. [Fatty acid and phospholipid metabolism, Biosynthesis]


Pssm-ID: 273113 [Multi-domain]  Cd Length: 316  Bit Score: 306.73  E-value: 6.39e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649   3 DVSRILKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPE 82
Cdd:TIGR00513  56 GAWQRLQLARHPDRPYTLDYIELIFDDFFELAGDRAYADDKAIVGGIARLDGRPVVVIGHQKGRDTKEKLRRNFGMPAPE 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  83 GYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVW 162
Cdd:TIGR00513 136 GYRKALRLMKMAERFKMPIITFIDTPGAYPGIGAEERGQSEAIARNLREMARLGVPVICTVIGEGGSGGALAIGVGDKVN 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 163 MLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPE------HGYFSseIVDIIKANLIEQITS 236
Cdd:TIGR00513 216 MLEYSTYSVISPEGCAAILWKDASKAPKAAEAMKITAPDLKELGLIDSIIPEplggahRNPLA--AAASLKEQLLADLAT 293

                         250       260
                  ....*....|....*....|
gi 1481397649 237 LQAKPLDQLLDERYQRFRKY 256
Cdd:TIGR00513 294 LDQLSTEELKNRRYQKLMSL 313
accA CHL00198
acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional
 8-255 2.09e-84

acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional


Pssm-ID: 214393 [Multi-domain]  Cd Length: 322  Bit Score: 254.74  E-value: 2.09e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649   8 LKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKA 87
Cdd:CHL00198   64 LHLVRQSERPTTLDYIPYILDEWIELHGDRGGSDDPALVGGIGKINGRTIVFLGHQRGRNTKENVLRNFGMPSPGGYRKA 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  88 LRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENT 167
Cdd:CHL00198  144 LRLMKHANKFGLPILTFIDTPGAWAGVKAEKLGQGEAIAVNLREMFSFEVPIICTIIGEGGSGGALGIGIGDSIMMLEYA 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 168 MYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPE-----HGYFSSeIVDIIKANLIEQITSLQAKPL 242
Cdd:CHL00198  224 VYTVATPEACAAILWKDSKKSLDAAEALKITSEDLKVLGIIDEIIPEpiggaQADPAS-ASKILKKKLIRQLDFLKILSP 302

                         250
                  ....*....|...
gi 1481397649 243 DQLLDERYQRFRK 255
Cdd:CHL00198  303 SELKAHRYEKFRK 315
PLN03230 PLN03230
acetyl-coenzyme A carboxylase carboxyl transferase; Provisional
 1-255 1.26e-73

acetyl-coenzyme A carboxylase carboxyl transferase; Provisional


Pssm-ID: 178769 [Multi-domain]  Cd Length: 431  Bit Score: 230.60  E-value: 1.26e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649   1 MTDVSRiLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPN 80
Cdd:PLN03230  125 LTPVQR-LSVARHPNRPTFLDHVLNMTDKWVELHGDRAGFDDPAIVCGIGSMEGMSFMFIGHQKGRNTKENIYRNFAMPQ 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  81 PEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ 160
Cdd:PLN03230  204 PNGYRKALRFMRHAEKFGFPILTFVDTPGAYAGIKAEELGQGEAIAFNLREMFGLRVPIIATVIGEGGSGGALAIGCGNR 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 161 VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPE--HGYFSSEIV--DIIKANLIEQITS 236
Cdd:PLN03230  284 MLMMENAVYYVASPEACAAILWKSAAAAPKAAEALRITAAELVKLGVVDEIVPEplGGAHSDPLQasKNIKEVILRHMKE 363

                         250
                  ....*....|....*....
gi 1481397649 237 LQAKPLDQLLDERYQRFRK 255
Cdd:PLN03230  364 LMKMDPEELLQDRAAKFRK 382
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 11-255 7.53e-67

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 220.50  E-value: 7.53e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  11 ARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRL 90
Cdd:PLN03229  155 ARHPNRPTFLDHIFNITDKFVELHGDRAGYDDPAIVTGIGTIDGKRYMFIGHQKGRNTKENIMRNFGMPTPHGYRKALRM 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  91 MKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENTMYA 170
Cdd:PLN03229  235 MYYADHHGFPIVTFIDTPGAYADLKSEELGQGEAIAHNLRTMFGLKVPIVSIVIGEGGSGGALAIGCANKLLMLENAVFY 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649 171 VLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPE-----HG--YFSSEivdIIKANLIEQITSLQAKPLD 243
Cdd:PLN03229  315 VASPEACAAILWKSAKAAPKAAEKLRITAQELCRLQIADGIIPEplggaHAdpSWTSQ---QIKIAINENMDELGKMDTE 391

                         250
                  ....*....|..
gi 1481397649 244 QLLDERYQRFRK 255
Cdd:PLN03229  392 ELLKHRMLKFRK 403
ACCA pfam03255
Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Acetyl co-enzyme A ...
 11-95 4.82e-54

Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Acetyl co-enzyme A carboxylase carboxyltransferase is composed of an alpha and beta subunit.


Pssm-ID: 427221 [Multi-domain]  Cd Length: 144  Bit Score: 171.05  E-value: 4.82e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  11 ARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRL 90
Cdd:pfam03255  60 ARHPERPYTLDYIEALFDDFIELHGDRLFGDDPAIVGGLARFDGQPVMVIGHQKGRDTKENIKRNFGMPHPEGYRKALRL 139


                  ....*
gi 1481397649  91 MKQAE 95
Cdd:pfam03255 140 MKLAE 144
Carboxyl_trans pfam01039
Carboxyl transferase domain; All of the members in this family are biotin dependent ...
 45-196 3.65e-08

Carboxyl transferase domain; All of the members in this family are biotin dependent carboxylases. The carboxyl transferase domain carries out the following reaction; transcarboxylation from biotin to an acceptor molecule. There are two recognized types of carboxyl transferase. One of them uses acyl-CoA and the other uses 2-oxoacid as the acceptor molecule of carbon dioxide. All of the members in this family utilize acyl-CoA as the acceptor molecule.


Pssm-ID: 426008 [Multi-domain]  Cd Length: 491  Bit Score: 53.42  E-value: 3.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  45 IVGGLAYLAGQPVTVIGIQKGKnlqdnLArnfGQPNPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEA 124
Cdd:pfam01039 282 VVTGFARLGGIPVGVVANQPRV-----GA---GVLFPDSADKAARFIRDCDAFNLPLVILADVPGFLPGQRQEYGGILKH 353

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1481397649 125 IAKNLMEMSDLKVPIIAIIIGEGGSGGALALA----VADQVWMLENTMYAVLSPEGFASILwkdgSRATEAAELMK 196
Cdd:pfam01039 354 GAKLLYALAEATVPKITVIPRKAYGGAYVVMDskinGADINFAWPTARIAVMGPEGAVEIK----FRKEKAAAEMR 425
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
26-138 1.37e-04

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 42.71  E-value: 1.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  26 IFDD--FMELHgdRHFsdDGAIVGGLAYLAGQPVTVIGiqkgknlqdnlarNfgQPN-------PEGYRKALRLMKQAEK 96
Cdd:COG4799   287 LVDGgsFFEFK--PLY--GPNIVTGFARIDGRPVGIVA-------------N--QPMvlagvldIDAADKAARFIRLCDA 347

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1481397649  97 FGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVP 138
Cdd:COG4799   348 FNIPLVFLVDVPGFMVGTEQERGGIIRHGAKLLYAVAEATVP 389
MmdA COG4799
Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];
12-117 2.09e-03

Acetyl-CoA carboxylase, carboxyltransferase component [Lipid transport and metabolism];


Pssm-ID: 443827 [Multi-domain]  Cd Length: 508  Bit Score: 38.85  E-value: 2.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1481397649  12 RDQGRLTTLDYANLIFDD--FMELH---GDRHFSDD-----GAIVGGLAYLAGQPVTVIGiqkgknlQDN--LArnfGQP 79
Cdd:COG4799    29 HARGKLTARERIDLLLDPgsFLELGalaGHRMYDDDdrvpgDGVVTGIGTVDGRPVVVVA-------NDFtvKG---GSL 98

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1481397649  80 NPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAE 117
Cdd:COG4799    99 GPMTAKKILRAQDIALENGLPVIYLVDSGGARLQEGVE 136
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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