NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1512896433|gb|RNQ55536|]
View 

iron-enterobactin ABC transporter permease [Klebsiella pneumoniae]

Protein Classification

iron-enterobactin ABC transporter permease( domain architecture ID 10793391)

iron-enterobactin ABC transporter permease is part of the binding-protein-dependent transport system for ferric enterobactin

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-329 6.18e-173

iron-enterobactin ABC transporter permease;


:

Pssm-ID: 182463  Cd Length: 330  Bit Score: 482.67  E-value: 6.18e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   1 MAPSRRLIASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALFGDAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQ 80
Cdd:PRK10440    2 IYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  81 SLTRNPLGSPDVMGFNTGAWSGVLVAMVLFGQNLTAIALAAMAGGVLTSLVVWLLAWRNGIETFRLIIIGIGVRAMLVAF 160
Cdd:PRK10440   82 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAF 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 161 NTWLLLRASLETALSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLV 240
Cdd:PRK10440  162 NTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLV 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 241 AVVLTAASTALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIA 320
Cdd:PRK10440  242 AVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIV 321


                  ....*....
gi 1512896433 321 LLIQESRKK 329
Cdd:PRK10440  322 LLIQESRKK 330
 
Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-329 6.18e-173

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 482.67  E-value: 6.18e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   1 MAPSRRLIASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALFGDAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQ 80
Cdd:PRK10440    2 IYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  81 SLTRNPLGSPDVMGFNTGAWSGVLVAMVLFGQNLTAIALAAMAGGVLTSLVVWLLAWRNGIETFRLIIIGIGVRAMLVAF 160
Cdd:PRK10440   82 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAF 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 161 NTWLLLRASLETALSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLV 240
Cdd:PRK10440  162 NTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLV 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 241 AVVLTAASTALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIA 320
Cdd:PRK10440  242 AVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIV 321


                  ....*....
gi 1512896433 321 LLIQESRKK 329
Cdd:PRK10440  322 LLIQESRKK 330
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 4-328 7.02e-117

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 340.94  E-value: 7.02e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   4 SRRLIASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALFGDAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQSLT 83
Cdd:COG4779    19 RRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSLT 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  84 RNPLGSPDVMGFNTGAWSGVLVAMVLFGQNLTAIALAAMAGGVLTSLVVWLLAWRNGIETFRLIIIGIGVRAMLVAFNTW 163
Cdd:COG4779    99 RNPLASPDIIGITAGASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNSY 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 164 LLLRASLETALSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVV 243
Cdd:COG4779   179 LLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAVA 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 244 LTAASTALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIALLI 323
Cdd:COG4779   259 LAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLLI 338


                  ....*
gi 1512896433 324 QESRK 328
Cdd:COG4779   339 RENRR 343
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 19-324 4.96e-70

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 220.48  E-value: 4.96e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  19 LLISLLGLAQGPVPLTIDQVFSALFGDAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQSLTRNPLGSPDVMGFNTG 98
Cdd:pfam01032   3 LLLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  99 AWSGVLVAMVLFG-QNLTAIALAAMAGGVLTSLVVWLLA-WRNGIETFRLIIIGIGVRAMLVAFNTWLLLRASLETALSA 176
Cdd:pfam01032  83 AALGAVLAILLGGsLSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQSI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 177 GLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVVLTAASTALAGPIS 256
Cdd:pfam01032 163 LFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIG 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1512896433 257 FIALVAPHIARRLSGTA-RWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIALLIQ 324
Cdd:pfam01032 243 FVGLIVPHIARLLVGANhRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 62-322 4.84e-43

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 149.24  E-value: 4.84e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  62 VLMALLIGAALGVSGAIFQSLTRNPLGSPDVMGFNTGAWSGVLVAMVLFGQ-NLTAIALAAMAGGVLTSLVVWLLAWRNG 140
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGlSNYALGAFAFAGALAIALLVLLLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 141 IETFRLIIIGIGVRAMLVAFNTWLLLRASlETALSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGD 220
Cdd:cd06550    81 LSPSKLILIGIVLSAFFSAGVILISLLSD-DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 221 DTACALGVQVERSRLLLMLVAVVLTAASTALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLALADYGAQRLFM 300
Cdd:cd06550   160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                         250       260
                  ....*....|....*....|..
gi 1512896433 301 PWQLPVGVLTVSLGGIYLIALL 322
Cdd:cd06550   240 PSELPVGPVTALLGAPYFLYLL 261
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 53-327 9.85e-23

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 96.46  E-value: 9.85e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  53 VVNEWRLPRVLMALLIGAALGVSGAIFQSLTRNPLGSPDVMGFNTGAWSGVLVAMVLFGQnlTAIALAAMAGGVLTSLVV 132
Cdd:TIGR03869  48 IVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVA--VLLPVAAFAGALLALAAT 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 133 WLLAWRNGIET-FRLIIIGIGVRAMLVAFNTWLLL-RASLETALSAGLWNAGSLNGLTWGKTwpSAPLILLMLVGSALLV 210
Cdd:TIGR03869 126 LGLARTLGTLTpTRTILAGLAVSQLCAAVTSFVIFwSATGDSYREILSWLMGSLAGATWGSV--AIAGGALLVVGLVLLA 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 211 --RRMRLLEMGDDTACALGVQVERSRLLLMLVAVVLTAASTALAGPISFIALVAPHIARRLSGTA-RWGLTQSALCGALL 287
Cdd:TIGR03869 204 sgRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRhRLLLPVSALAGAVF 283

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1512896433 288 LALADYGAQRLFMPWQLPVGVLTVSLGGIYLIALLIQESR 327
Cdd:TIGR03869 284 LVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
 
Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-329 6.18e-173

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 482.67  E-value: 6.18e-173
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   1 MAPSRRLIASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALFGDAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQ 80
Cdd:PRK10440    2 IYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  81 SLTRNPLGSPDVMGFNTGAWSGVLVAMVLFGQNLTAIALAAMAGGVLTSLVVWLLAWRNGIETFRLIIIGIGVRAMLVAF 160
Cdd:PRK10440   82 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAF 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 161 NTWLLLRASLETALSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLV 240
Cdd:PRK10440  162 NTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLV 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 241 AVVLTAASTALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIA 320
Cdd:PRK10440  242 AVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIV 321


                  ....*....
gi 1512896433 321 LLIQESRKK 329
Cdd:PRK10440  322 LLIQESRKK 330
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 4-328 7.02e-117

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 340.94  E-value: 7.02e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   4 SRRLIASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALFGDAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQSLT 83
Cdd:COG4779    19 RRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSLT 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  84 RNPLGSPDVMGFNTGAWSGVLVAMVLFGQNLTAIALAAMAGGVLTSLVVWLLAWRNGIETFRLIIIGIGVRAMLVAFNTW 163
Cdd:COG4779    99 RNPLASPDIIGITAGASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNSY 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 164 LLLRASLETALSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVV 243
Cdd:COG4779   179 LLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAVA 258

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 244 LTAASTALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIALLI 323
Cdd:COG4779   259 LAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLLI 338


                  ....*
gi 1512896433 324 QESRK 328
Cdd:COG4779   339 RENRR 343
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 19-324 4.96e-70

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 220.48  E-value: 4.96e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  19 LLISLLGLAQGPVPLTIDQVFSALFGDAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQSLTRNPLGSPDVMGFNTG 98
Cdd:pfam01032   3 LLLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  99 AWSGVLVAMVLFG-QNLTAIALAAMAGGVLTSLVVWLLA-WRNGIETFRLIIIGIGVRAMLVAFNTWLLLRASLETALSA 176
Cdd:pfam01032  83 AALGAVLAILLGGsLSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQSI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 177 GLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVVLTAASTALAGPIS 256
Cdd:pfam01032 163 LFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIG 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1512896433 257 FIALVAPHIARRLSGTA-RWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIALLIQ 324
Cdd:pfam01032 243 FVGLIVPHIARLLVGANhRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 25-323 1.62e-65

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 208.39  E-value: 1.62e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  25 GLAQGPVPLTIDQVFSALFG-DAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQSLTRNPLGSPDVMGFNTGAWSGV 103
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGpDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 104 LVAMVLFGQ-NLTAIALAAMAGGVLTSLVVWLLAWRN-GIETFRLIIIGIGVRAMLVAFNTWLLLRASLETALSAGLWNA 181
Cdd:COG0609    81 VLAIVLGGGlSALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWLM 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 182 GSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVVLTAASTALAGPISFIALV 261
Cdd:COG0609   161 GSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLV 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1512896433 262 APHIARRLSGT-ARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIALLI 323
Cdd:COG0609   241 VPHIARLLVGPdHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLR 303
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
5-328 3.98e-48

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 171.18  E-value: 3.98e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   5 RRLIASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALFgdaprnvaMVVNEWRLPRVLMALLIGAALGVSGAIFQSLTR 84
Cdd:PRK10577  352 RRVLAWLLALGLLLLLALVVALSFGRDAHGWNWLSGQLL--------DALLPLRLPRLLAALLAGAMLAVAGTLLQRLTR 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  85 NPLGSPDVMGFNTGAWSGVLVAMVLFGQN-LTAIALAAMAGGVLTSLVVWLLAWRNGIETFRLIIIGIGVRAMLVAFNTW 163
Cdd:PRK10577  424 NPLASPEVLGISSGAGLGVVLALFLVPGAgFGWLLAAALLGALAALALILLLARRGGFAPERLLLTGIALSALFTALIQL 503

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 164 LLLRASLETAlSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVV 243
Cdd:PRK10577  504 LLASGDPRAA-QLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAAL 582

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 244 LTAASTALAGPISFIALVAPHIARRLSG-TARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIALL 322
Cdd:PRK10577  583 LTAAATATVGPLSFVGLMAPHLARMLGGrRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLL 662


                  ....*.
gi 1512896433 323 IQESRK 328
Cdd:PRK10577  663 RRSRRR 668
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-322 2.18e-44

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 160.77  E-value: 2.18e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   1 MAPSRRLIASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALFGDAPRNVA-MVVNEWRLPRVLMALLIGAALGVSGAIF 79
Cdd:PRK10577    4 LMSRRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLEqLLLHYSRLPRLAIALLVGAALGLAGALL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  80 QSLTRNPLGSPDVMGFNTGAWSGVLVAMVLFGQNLTAIA-LAAMAGGVLTSLVVWLLAWRNGIETFRLIIIGIGVRAMLV 158
Cdd:PRK10577   84 QQVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASqLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYLG 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 159 AFNTWLLLrASLETALSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLM 238
Cdd:PRK10577  164 ALTTLLLL-FNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAAL 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 239 LVAVVLTAASTALAGPISFIALVAPHIARRLSG-TARWGLTQSALCGALLLALADYGAQRLFMPWQ--LPVGVLTVSLGG 315
Cdd:PRK10577  243 ALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGArRLRARLPLSPLIGALLLLLTDQLVRLLAGVGGelLPTGAVTALIGA 322


                  ....*..
gi 1512896433 316 IYLIALL 322
Cdd:PRK10577  323 PLLLWLL 329
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 62-322 4.84e-43

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 149.24  E-value: 4.84e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  62 VLMALLIGAALGVSGAIFQSLTRNPLGSPDVMGFNTGAWSGVLVAMVLFGQ-NLTAIALAAMAGGVLTSLVVWLLAWRNG 140
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGlSNYALGAFAFAGALAIALLVLLLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 141 IETFRLIIIGIGVRAMLVAFNTWLLLRASlETALSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGD 220
Cdd:cd06550    81 LSPSKLILIGIVLSAFFSAGVILISLLSD-DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 221 DTACALGVQVERSRLLLMLVAVVLTAASTALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLALADYGAQRLFM 300
Cdd:cd06550   160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239

                         250       260
                  ....*....|....*....|..
gi 1512896433 301 PWQLPVGVLTVSLGGIYLIALL 322
Cdd:cd06550   240 PSELPVGPVTALLGAPYFLYLL 261
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
8-324 3.81e-39

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 140.57  E-value: 3.81e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   8 IASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALFGDAPRNvaMVVNEWRLPRVLMALLIGAALGVSGAIFQSLTRNPL 87
Cdd:PRK09777    3 IALVIFITLALAGCALLSLRMGVIPLPWRALLTDWQAGDEHY--YVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  88 GSPDVMGFNTGAWSGVLVAMVLF-GQNLTAIALAAMAGGVLTSLVVWLLAWRNgiETFRLIIIGIGVRAMLVAFNTWLLL 166
Cdd:PRK09777   81 ASPDILGVNHAASLASVGALLLFpSLPVMWLPLLAFIGGMAGLILLKMLAGTH--QPMKLALTGVALSALWASLTDYLML 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 167 RASLETAlSAGLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVVLTA 246
Cdd:PRK09777  159 SRPQDIN-NALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTA 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1512896433 247 ASTALAGPISFIALVAPHIARRL-SGTARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIALLIQ 324
Cdd:PRK09777  238 TGVAACGPISFIGLVVPHLMRSLvGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLLVR 316
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
30-314 3.46e-32

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 122.11  E-value: 3.46e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  30 PVPLTIDQVFSALF-GDAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQSLTRNPLGSPDVMGFNTGAWSGVLVAMV 108
Cdd:PRK11228   22 AIPISAADALNALLpGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 109 LFGQNLT--AIALAAMAGGVLTSLVVWLL--AWRNGIETFRLIIIGIGVRAMLVAFNTWLLLRASlETALSAGLWNAGSL 184
Cdd:PRK11228  102 LSPTPFAgySLAFIAACGGGLSWLLVMTAggGWRHTHDRNRLILAGIALSALCMALTRITLLLAE-DHAYGIFYWLAGGV 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 185 NGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVVLTAASTALAGPISFIALVAPH 264
Cdd:PRK11228  181 SHARWQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPH 260

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1512896433 265 IARRLSG-TARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLG 314
Cdd:PRK11228  261 LARFWIGyDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIG 311
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 4-272 6.16e-32

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 121.50  E-value: 6.16e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   4 SRRLIASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALFgdaprnvAMVVNEWRLPRVLMALLIGAALGVSGAIFQSLT 83
Cdd:COG4139     8 RRRDRRWLLLLLLLLLLLFVLSLCAGEVWIPPTQWLSEAW-------QLFVWQLRLPRTLAAVLVGASLAVSGAVMQALF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  84 RNPLGSPDVMGFNTGAWSGVLVAMVLFGQNLT--AIALAAMAGGVLTSLVVWLLAwRNGIETFRLIIIGIGVRAMLVAFN 161
Cdd:COG4139    81 ENPLAEPGLLGISNGAGVGLVLVVLLGGGLLPpwLLSLAAIAGALLVTLLLLAFA-RRRLSNARLLLIGVALGIICSAIM 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 162 TWLLLRASLETALSAGLWNAGSLNGLTWGKTWPSAPLILLmLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVA 241
Cdd:COG4139   160 TWAVYFSSSLDLRQLMYWMMGSFGGVDWRQLWLLLALLPV-LLWLCLQGKPLNLLLLGENQARQLGLSVHRWRNLLVLAT 238

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1512896433 242 VVLTAASTALAGPISFIALVAPHIARRLSGT 272
Cdd:COG4139   239 GLLVGVSVALAGPIGFVGLVVPHLLRLLGTT 269
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
1-327 1.69e-30

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 117.89  E-value: 1.69e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   1 MAPSRRLIASCLLLMAAsLLISLLGLAQGPVPLTIDQVFSALFGDAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQ 80
Cdd:PRK10441    4 SVAVTRAIAVPGLLLLL-IIATALSLLIGAKSLPASVVLEALSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  81 SLTRNPLGSPDVMGFNTGAWSGVLVAMVLFG-QNLTAIALAAMAGGVLTSLVVWLLAWRNG--IETFRLIIIGIGVRAML 157
Cdd:PRK10441   83 TLTRNPLADPGLLGVNAGASFAIVLGAALFGySSAQEQLAMAFAGALVASLIVAFTGSQGGgqLSPVRLTLAGVALAAVL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 158 VAFNTWL-LLRASLETALSagLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLL 236
Cdd:PRK10441  163 EGLTSGIaLLNPDVYDQLR--FWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLI 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 237 LMLVAVVLTAASTALAGPISFIALVAPHIARRLSGT-ARWGLTQSALCGALLLALADYGAqRLFMPWQLPVGVLTVSLGG 315
Cdd:PRK10441  241 GLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGAdHRWSLPVTLLATPALLLFADIIG-RLLVPGELRVSVVSAFIGA 319

                         330
                  ....*....|..
gi 1512896433 316 IYLIALLIQESR 327
Cdd:PRK10441  320 PVLIFLVRRKTR 331
btuC PRK09535
cobalamin ABC transporter permease BtuC;
17-322 8.14e-30

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 116.77  E-value: 8.14e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  17 ASLLISLLGLAQGPVPL-TIDQVFSALFG-DAPRNVAMVVNEWRLPRVLMALLIGAALGVSGAIFQSLTRNPLGSPDVMG 94
Cdd:PRK09535   52 VAVTTHGVPVLSVGLSLpAPDLEYASPFSfAVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIG 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  95 FNTGAWSGVLVAMVLFGQNLTAIALAAMAGGVLTSLVVWLLAWRNG-IETFRLIIIGIGVRAMLVAFNTWLLLRA--SLE 171
Cdd:PRK09535  132 VSSGAAVGAVAAIVLPLAVPFGLQAAAFAGALVAAFGVYAIATENGrTPVATLLLAGVAVQTFLGAVISYLLLHSgeSLR 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 172 TALsagLWNAGSLNGLTWGKTWPSAPLILLMLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVVLTAASTAL 251
Cdd:PRK09535  212 RAV---YWLMGHLHGSTWSDVEVALPVVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAV 288

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1512896433 252 AGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLALADYGAQRLfMPWQLPVGVLTVSLGGIYLIALL 322
Cdd:PRK09535  289 AGVIGFVGLIVPHVMRLLVGPDHRILLPTSALAGASFLVATDTVARS-GPAEVPVGIVTAALGAPFFLYLL 358
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 5-327 4.71e-26

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 105.81  E-value: 4.71e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433   5 RRLIASCLLLMAASLLISLLGLAQGPVPLTIDQVFSALfgdaprnVAMVVNEWRLPRVLMALLIGAALGVSGAIFQSLTR 84
Cdd:PRK03784   12 RRNRRWLLGLSVLLLLALLLSLCAGEQWISPGDWLSPR-------GELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  85 NPLGSPDVMGFNTGAWSGVLVAMVLFGQNLT--AIALAAMAGGVLTSLVVWLLAWRNGIETFRLIIIGIGVRAMLVAFNT 162
Cdd:PRK03784   85 NPLAEPGLLGVSNGAGVALVAAVLLGQGLLPpwALSLCAIAGALLITLILLRFARRHRLSTSRLLLAGVALGIICSALMT 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 163 WLLLRASLETALSAGLWNAGSLNGLTWGKTWPSAPLILLmLVGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAV 242
Cdd:PRK03784  165 WAVYFSTSLDLRQLMYWMMGGFGGVDWRQSWLMLALLPV-LIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATG 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 243 VLTAASTALAGPISFIALVAPHIARRLSGT-ARWGLTQSALCGALLLALADYGAQRLFMPWQLPVGVLTVSLGGIYLIAL 321
Cdd:PRK03784  244 WLVGVSVALAGAIGFIGLVIPHILRLCGLTdHRVLLPGCALAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWL 323


                  ....*.
gi 1512896433 322 LIQESR 327
Cdd:PRK03784  324 LLRSHR 329
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 53-327 9.85e-23

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 96.46  E-value: 9.85e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  53 VVNEWRLPRVLMALLIGAALGVSGAIFQSLTRNPLGSPDVMGFNTGAWSGVLVAMVLFGQnlTAIALAAMAGGVLTSLVV 132
Cdd:TIGR03869  48 IVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVA--VLLPVAAFAGALLALAAT 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 133 WLLAWRNGIET-FRLIIIGIGVRAMLVAFNTWLLL-RASLETALSAGLWNAGSLNGLTWGKTwpSAPLILLMLVGSALLV 210
Cdd:TIGR03869 126 LGLARTLGTLTpTRTILAGLAVSQLCAAVTSFVIFwSATGDSYREILSWLMGSLAGATWGSV--AIAGGALLVVGLVLLA 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 211 --RRMRLLEMGDDTACALGVQVERSRLLLMLVAVVLTAASTALAGPISFIALVAPHIARRLSGTA-RWGLTQSALCGALL 287
Cdd:TIGR03869 204 sgRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRhRLLLPVSALAGAVF 283

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1512896433 288 LALADYGAQRLFMPWQLPVGVLTVSLGGIYLIALLIQESR 327
Cdd:TIGR03869 284 LVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
CeuC COG4605
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
 58-328 9.16e-11

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443655  Cd Length: 317  Bit Score: 61.66  E-value: 9.16e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433  58 RLPRVLMALLIGAALGVSGAIFQSLTRNPLGSPDVMGFNT--GAWSGVLV------AMVLFGQNLTAIALAAMAGGVLTS 129
Cdd:COG4605    39 RGTKLAAMLLVAIAIAVSTVLFQTITNNRILTPSIMGFDSlyVLIQTLLVfflgsaGLAALNPLLNFLLEVALMVGFSLL 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 130 LVVWLLAwRNGIETFRLIIIGIGVRAMLVAFNTWLLLR------ASLETALSAglwnagSLNGLTWGKTWPSAPLILLML 203
Cdd:COG4605   119 LYRWLFR-GGRRNLHLLLLVGVVLGTLFRSLSSFLQRLidpnefDVLQDRLFA------SFNNVNTDLLLIAAVIVLLAL 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1512896433 204 VGSALLVRRMRLLEMGDDTACALGVQVERSRLLLMLVAVVLTAASTALAGPISFIALVAPHIARRLSGTAR--WGLTQSA 281
Cdd:COG4605   192 LLLWRLRRRLDVLALGRDQAINLGVDYRRVVRRLLILVAVLVAVSTALVGPITFLGLLVANLAYQLFGTYRhrYLLPAAA 271

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1512896433 282 LCGALLLALADYGAQRLFMpWQLPVGVLTVSLGGIYLIALLIQESRK 328
Cdd:COG4605   272 LIGVIALVGGQFVVEHVFN-FSTTLSVIIEFVGGIYFLYLLLRKRRL 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH