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Conserved domains on  [gi|1513525363|gb|RNW65808|]
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PTS fructose transporter subunit IIC [Klebsiella pneumoniae subsp. pneumoniae]

Protein Classification

PTS fructose transporter subunit IIC( domain architecture ID 10003452)

PTS fructose transporter subunit IIC forms the translocation channel and contains the specific substrate-binding site of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS) that catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FrwC COG1299
Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and ...
11-349 1.07e-106

Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440910 [Multi-domain]  Cd Length: 469  Bit Score: 321.07  E-value: 1.07e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  11 NPKGHLLTAISFLIPIVCGSGFIIAIGMGLGGTVQDTLTPGQFDVWQAMATLGAKALGLLPVVIAVGISGSIAGKPGIAP 90
Cdd:COG1299   131 GIYKHLMTGVSYMLPFVVAGGILIALSFLFGIYAFDPGDVSEGTLAAALFQIGGAAFGLMVPVLAGYIAYSIADRPGLAP 210
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  91 GFVVGLAANTISAGFIGGMIGGYIAGYIALAIIKNVKVPDWARGLMPTLIVPFFASIISCMIMVYIIGTPIGIFTEALTS 170
Cdd:COG1299   211 GFIGGLLANNIGAGFLGGIIAGFLAGYVVLWLKKKIKLPKSLEGLKPILIIPLLGTLITGLLMIYVIGPPIAALNTALTN 290
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 171 FLRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAFVLTLQAQGINEPITALQLVNTATPIGFGLAFFIAkllrKNIYNR 250
Cdd:COG1299   291 WLNSMSGSNAVLLGAILGAMMAFDMGGPVNKAAYAFGTGLLASGIYAPMAAVMAAGMVPPLGLALATLLF----KKKFTE 366
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 251 EEVETLKSAVPMGIVNIVEGSIPIVMNDIVRGIAAAAIGGACGGAVTMVYGADATVPFGGVLMIPTMSHPMAGIMALLVN 330
Cdd:COG1299   367 EEREAGKAAFILGLSFITEGAIPFAAADPLRVIPSNMIGSAVAGALSMLFGVTLPAPHGGIFVLPLVSNPLLYLLAIAIG 446
                         330
                  ....*....|....*....
gi 1513525363 331 IVVTATVYAVIKKDIPRDV 349
Cdd:COG1299   447 TVVTALLLGLLKKPVEKKE 465
 
Name Accession Description Interval E-value
FrwC COG1299
Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and ...
11-349 1.07e-106

Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism];


Pssm-ID: 440910 [Multi-domain]  Cd Length: 469  Bit Score: 321.07  E-value: 1.07e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  11 NPKGHLLTAISFLIPIVCGSGFIIAIGMGLGGTVQDTLTPGQFDVWQAMATLGAKALGLLPVVIAVGISGSIAGKPGIAP 90
Cdd:COG1299   131 GIYKHLMTGVSYMLPFVVAGGILIALSFLFGIYAFDPGDVSEGTLAAALFQIGGAAFGLMVPVLAGYIAYSIADRPGLAP 210
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  91 GFVVGLAANTISAGFIGGMIGGYIAGYIALAIIKNVKVPDWARGLMPTLIVPFFASIISCMIMVYIIGTPIGIFTEALTS 170
Cdd:COG1299   211 GFIGGLLANNIGAGFLGGIIAGFLAGYVVLWLKKKIKLPKSLEGLKPILIIPLLGTLITGLLMIYVIGPPIAALNTALTN 290
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 171 FLRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAFVLTLQAQGINEPITALQLVNTATPIGFGLAFFIAkllrKNIYNR 250
Cdd:COG1299   291 WLNSMSGSNAVLLGAILGAMMAFDMGGPVNKAAYAFGTGLLASGIYAPMAAVMAAGMVPPLGLALATLLF----KKKFTE 366
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 251 EEVETLKSAVPMGIVNIVEGSIPIVMNDIVRGIAAAAIGGACGGAVTMVYGADATVPFGGVLMIPTMSHPMAGIMALLVN 330
Cdd:COG1299   367 EEREAGKAAFILGLSFITEGAIPFAAADPLRVIPSNMIGSAVAGALSMLFGVTLPAPHGGIFVLPLVSNPLLYLLAIAIG 446
                         330
                  ....*....|....*....
gi 1513525363 331 IVVTATVYAVIKKDIPRDV 349
Cdd:COG1299   447 TVVTALLLGLLKKPVEKKE 465
PRK10712 PRK10712
PTS system fructose-specific transporter subunits IIBC; Provisional
8-343 6.29e-59

PTS system fructose-specific transporter subunits IIBC; Provisional


Pssm-ID: 236740 [Multi-domain]  Cd Length: 563  Bit Score: 199.97  E-value: 6.29e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363   8 QAANPKGHLLTAISFLIPIVCGSGFIIAIGMGLGGT---VQDTLTPGqfdvwqAMATLGAKALGLLPVVIAVGISGSIAG 84
Cdd:PRK10712  222 ESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEafkEPGTLAAA------LMQIGGGSAFALMVPVLAGYIAFSIAD 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  85 KPGIAPGFVVGLAANTISAGFIGGMIGGYIAGYIALAIIKNVKVPDWARGLMPTLIVPFFASIISCMIMVYIIGTPIGIF 164
Cdd:PRK10712  296 RPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYVAKLISTKLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGI 375
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 165 TEALTSFLRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAFVLTLQAQGINEPITALQLVNTATPIGFGLAFFIAKllR 244
Cdd:PRK10712  376 LEGLTHWLQTMGTANAVLLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYAPMAAIMAAGMVPPLAMGLATMVAR--R 453
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 245 KniYNREEVETLKSAVPMGIVNIVEGSIPIVMNDIVRGIAAAAIGGACGGAVTMVYGADATVPFGG--VLMIPTMSHPMA 322
Cdd:PRK10712  454 K--FDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIGAKLMAPHGGlfVLLIPGAITPVL 531
                         330       340
                  ....*....|....*....|..
gi 1513525363 323 G-IMALLVNIVVTATVYAVIKK 343
Cdd:PRK10712  532 GyLVAIIAGTLVAGLAYAFLKR 553
PTS_IIC_fructo TIGR01427
PTS system, fructose subfamily, IIC component; This model represents the IIC component, or IIC ...
15-342 2.55e-53

PTS system, fructose subfamily, IIC component; This model represents the IIC component, or IIC region of a IIABC or IIBC polypeptide of a phosphotransferase system for carbohydrate transport. Members of this family belong to the fructose-specific subfamily of the broader family (pfam02378) of PTS IIC proteins. Members should be found as part of the same chain or in the same operon as fructose family IIA (TIGR00848) and IIB (TIGR00829) protein regions. A number of bacterial species have members in two different branches of this subfamily, suggesting some diversity in substrate specificity of its members.


Pssm-ID: 273617  Cd Length: 346  Bit Score: 179.54  E-value: 2.55e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  15 HLLTAISFLIPIVCGSGFIIAIGMGLGGTVQDTLTPGQFDVWQAMATLGAK-ALGLLPVVIAVGISGSIAGKPGIAPGFV 93
Cdd:TIGR01427  18 HLLTGVSYMLPFVVAGGIIIAISFLFGINAANNTGGNFNDLANWLMQIGGGvAFALMVPILAGYIAYSIADRPGLAPGMI 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  94 VGLAANTISAGFIGGMIGGYIAGYIALAIIKNVK--VPDWARGLMPTLIVPFFASIISCmIMVYIIGTPIGIFTEALTSF 171
Cdd:TIGR01427  98 AGLIANNFNSGFLGGIIAGFLAGYVVKGLQKYIKkkLPQSLRGLKPILIIPLLGTLIVG-ALIYGINIPVAYLNYGLSNW 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 172 LRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAF-VLTLQAQGINePITALQLVNTATPIGFGLAFFIakllRKNIYNR 250
Cdd:TIGR01427 177 LNIMGSPNAALLGAIIGGMMAFDMGGPVNKAAYAFgVGLIAAQGYI-PMAAAMAAGMVPPLGIALATSI----FKNRFTK 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 251 EEVETLKSAVPMGIVNIVEGSIPIVMNDIVRGIAAAAIGGACGGAVTMVYGADATVPFGGVLMIP---TMSHPMAGIMAL 327
Cdd:TIGR01427 252 EEREAGKACYVLGLCFISEGAIPFAAADPKRVIPACIIGSAVTGAISMAFGVTLRAPHGGIFVLPilkAVVALLCYLIAI 331
                         330
                  ....*....|....*
gi 1513525363 328 LVNIVVTATVYAVIK 342
Cdd:TIGR01427 332 IVGSLVTAVIIGFLK 346
PTS_EIIC pfam02378
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ...
19-191 1.73e-04

Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.


Pssm-ID: 367061  Cd Length: 315  Bit Score: 43.10  E-value: 1.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  19 AISFLIPIVCGSGFIIAIGMGLGGTVQDTLTPGQFDVWQA--MATLGAKALGLLPVVIAVGISGSIAG-KPGIAPGFVVG 95
Cdd:pfam02378   3 GFMPPIPLLIAGGILLGLGNLPNDTTGLPAGGFTGDSPLAeiLKQAGSAAFGILPILFAIGIAYGLAGgDGVAGAAGLIG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  96 LAA-------------------------NTISAGFIGGMIGGYIAGYIALAIIKNV--KVPDWARGLMPTLIVPFFASII 148
Cdd:pfam02378  83 LLSfnlaaaisvaltaaglsgggnilgiGLGATGVFGAIIPGLLAAYLYNRFEKNItiKLPDSLPFFVGKRFVPIITGFV 162
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1513525363 149 SCMIMVYIIGTPIGIFTEALTSFLRSMGTSSNFVLGAVIGALC 191
Cdd:pfam02378 163 TLLVIGPVLGLIWPAIQGGLNALGLLLIIAGGILGGLIFGFLE 205
 
Name Accession Description Interval E-value
FrwC COG1299
Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and ...
11-349 1.07e-106

Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism];


Pssm-ID: 440910 [Multi-domain]  Cd Length: 469  Bit Score: 321.07  E-value: 1.07e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  11 NPKGHLLTAISFLIPIVCGSGFIIAIGMGLGGTVQDTLTPGQFDVWQAMATLGAKALGLLPVVIAVGISGSIAGKPGIAP 90
Cdd:COG1299   131 GIYKHLMTGVSYMLPFVVAGGILIALSFLFGIYAFDPGDVSEGTLAAALFQIGGAAFGLMVPVLAGYIAYSIADRPGLAP 210
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  91 GFVVGLAANTISAGFIGGMIGGYIAGYIALAIIKNVKVPDWARGLMPTLIVPFFASIISCMIMVYIIGTPIGIFTEALTS 170
Cdd:COG1299   211 GFIGGLLANNIGAGFLGGIIAGFLAGYVVLWLKKKIKLPKSLEGLKPILIIPLLGTLITGLLMIYVIGPPIAALNTALTN 290
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 171 FLRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAFVLTLQAQGINEPITALQLVNTATPIGFGLAFFIAkllrKNIYNR 250
Cdd:COG1299   291 WLNSMSGSNAVLLGAILGAMMAFDMGGPVNKAAYAFGTGLLASGIYAPMAAVMAAGMVPPLGLALATLLF----KKKFTE 366
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 251 EEVETLKSAVPMGIVNIVEGSIPIVMNDIVRGIAAAAIGGACGGAVTMVYGADATVPFGGVLMIPTMSHPMAGIMALLVN 330
Cdd:COG1299   367 EEREAGKAAFILGLSFITEGAIPFAAADPLRVIPSNMIGSAVAGALSMLFGVTLPAPHGGIFVLPLVSNPLLYLLAIAIG 446
                         330
                  ....*....|....*....
gi 1513525363 331 IVVTATVYAVIKKDIPRDV 349
Cdd:COG1299   447 TVVTALLLGLLKKPVEKKE 465
PRK10712 PRK10712
PTS system fructose-specific transporter subunits IIBC; Provisional
8-343 6.29e-59

PTS system fructose-specific transporter subunits IIBC; Provisional


Pssm-ID: 236740 [Multi-domain]  Cd Length: 563  Bit Score: 199.97  E-value: 6.29e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363   8 QAANPKGHLLTAISFLIPIVCGSGFIIAIGMGLGGT---VQDTLTPGqfdvwqAMATLGAKALGLLPVVIAVGISGSIAG 84
Cdd:PRK10712  222 ESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEafkEPGTLAAA------LMQIGGGSAFALMVPVLAGYIAFSIAD 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  85 KPGIAPGFVVGLAANTISAGFIGGMIGGYIAGYIALAIIKNVKVPDWARGLMPTLIVPFFASIISCMIMVYIIGTPIGIF 164
Cdd:PRK10712  296 RPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYVAKLISTKLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGI 375
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 165 TEALTSFLRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAFVLTLQAQGINEPITALQLVNTATPIGFGLAFFIAKllR 244
Cdd:PRK10712  376 LEGLTHWLQTMGTANAVLLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYAPMAAIMAAGMVPPLAMGLATMVAR--R 453
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 245 KniYNREEVETLKSAVPMGIVNIVEGSIPIVMNDIVRGIAAAAIGGACGGAVTMVYGADATVPFGG--VLMIPTMSHPMA 322
Cdd:PRK10712  454 K--FDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIGAKLMAPHGGlfVLLIPGAITPVL 531
                         330       340
                  ....*....|....*....|..
gi 1513525363 323 G-IMALLVNIVVTATVYAVIKK 343
Cdd:PRK10712  532 GyLVAIIAGTLVAGLAYAFLKR 553
PTS_IIC_fructo TIGR01427
PTS system, fructose subfamily, IIC component; This model represents the IIC component, or IIC ...
15-342 2.55e-53

PTS system, fructose subfamily, IIC component; This model represents the IIC component, or IIC region of a IIABC or IIBC polypeptide of a phosphotransferase system for carbohydrate transport. Members of this family belong to the fructose-specific subfamily of the broader family (pfam02378) of PTS IIC proteins. Members should be found as part of the same chain or in the same operon as fructose family IIA (TIGR00848) and IIB (TIGR00829) protein regions. A number of bacterial species have members in two different branches of this subfamily, suggesting some diversity in substrate specificity of its members.


Pssm-ID: 273617  Cd Length: 346  Bit Score: 179.54  E-value: 2.55e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  15 HLLTAISFLIPIVCGSGFIIAIGMGLGGTVQDTLTPGQFDVWQAMATLGAK-ALGLLPVVIAVGISGSIAGKPGIAPGFV 93
Cdd:TIGR01427  18 HLLTGVSYMLPFVVAGGIIIAISFLFGINAANNTGGNFNDLANWLMQIGGGvAFALMVPILAGYIAYSIADRPGLAPGMI 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  94 VGLAANTISAGFIGGMIGGYIAGYIALAIIKNVK--VPDWARGLMPTLIVPFFASIISCmIMVYIIGTPIGIFTEALTSF 171
Cdd:TIGR01427  98 AGLIANNFNSGFLGGIIAGFLAGYVVKGLQKYIKkkLPQSLRGLKPILIIPLLGTLIVG-ALIYGINIPVAYLNYGLSNW 176
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 172 LRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAF-VLTLQAQGINePITALQLVNTATPIGFGLAFFIakllRKNIYNR 250
Cdd:TIGR01427 177 LNIMGSPNAALLGAIIGGMMAFDMGGPVNKAAYAFgVGLIAAQGYI-PMAAAMAAGMVPPLGIALATSI----FKNRFTK 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 251 EEVETLKSAVPMGIVNIVEGSIPIVMNDIVRGIAAAAIGGACGGAVTMVYGADATVPFGGVLMIP---TMSHPMAGIMAL 327
Cdd:TIGR01427 252 EEREAGKACYVLGLCFISEGAIPFAAADPKRVIPACIIGSAVTGAISMAFGVTLRAPHGGIFVLPilkAVVALLCYLIAI 331
                         330
                  ....*....|....*
gi 1513525363 328 LVNIVVTATVYAVIK 342
Cdd:TIGR01427 332 IVGSLVTAVIIGFLK 346
PRK10478 PRK10478
PTS fructose transporter subunit EIIC;
11-363 1.03e-51

PTS fructose transporter subunit EIIC;


Pssm-ID: 182490  Cd Length: 359  Bit Score: 175.75  E-value: 1.03e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  11 NPKGHLLTAISFLIPIVCGSGFIIAIGMGLGG--TVQDTLTPGQFdvwQAMATLGAKALGLLPVVIAVGISGSIAGKPGI 88
Cdd:PRK10478   10 NTRQHLMTGVSHMIPFVVAGGILLAVSVMLYGkgAVPDAVADPNL---KKLFDIGVAGLTLMVPFLAAYIGYSIADRSAL 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  89 APGFVVGLAANTISAGFIGGMIGGYIAGYIALAIiKNVKVPDWARGLMPTLIVPFFASIISCMIMVYIIGTPIGIFTEAL 168
Cdd:PRK10478   87 APCAIGAWVGNSFGAGFFGALIAGIIGGIVVHYL-KKIPVHKVLRSVMPIFIIPIVGTLITAGIMMWGLGEPIGALTNSL 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 169 TSFLRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAFVLTLQAQGINEPITALQLVNTATPIGFGLaffiAKLLRKNIY 248
Cdd:PRK10478  166 TQWLQGMQQGSIVMLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAIAAVAICVPPLGMGL----ATLIGRKNF 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 249 NREEVETLKSAVPMGIVNIVEGSIPIVMNDIVRGIAAAAIGGACGGAVTMVYGADATVPFGGVLMIPTMSHPMAGIMALL 328
Cdd:PRK10478  242 SAEERETGKAALVMGCVGVTEGAIPFAAADPLRVIPSIMVGSVCGAVTAALFGAQCYAGWGGLIVLPVVDGKLGYIAAVA 321
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1513525363 329 VNIVVTATVYAVIKKDIPRDViVDNDYEEEDIDLD 363
Cdd:PRK10478  322 VGAVVTAVCVNVLKSLARKNG-SSTDEKEDDLDLD 355
PRK09765 PRK09765
PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional
13-281 4.31e-41

PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional


Pssm-ID: 182066 [Multi-domain]  Cd Length: 631  Bit Score: 152.58  E-value: 4.31e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  13 KGHLLTAISFLIPIVCGSGFIIAIGMGLGGTVQDTLTPGQFDVWQAM-ATLGAKALGLLPV-VIAVGISGSIAGKPGIAP 90
Cdd:PRK09765  287 KQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMyRKLGGGLLGTLMVpVLAAYTAYSLADKPALAP 366
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  91 GFVVGLAANTISAGFIGGMIGGYIAGYIALAIIKNVKVPDWARGLMPTLIVPFFASIISCMIMVYIIGTPIGIFTEALTS 170
Cdd:PRK09765  367 GFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTA 446
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 171 FLRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAFVLTLQAQGINEPITALQLVNTATpiGFGLAffIAKLLRKNIYNR 250
Cdd:PRK09765  447 WLNGLSGSNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVS--AFTVT--ASTMLAPRLFKE 522
                         250       260       270
                  ....*....|....*....|....*....|.
gi 1513525363 251 EEVETLKSAVPMGIVNIVEGSIPIVMNDIVR 281
Cdd:PRK09765  523 FEIETGKSTWLLGLAGITEGAIPMAIEDPLR 553
PRK11404 PRK11404
PTS fructose-like transporter subunit IIBC;
15-331 4.75e-22

PTS fructose-like transporter subunit IIBC;


Pssm-ID: 183120 [Multi-domain]  Cd Length: 482  Bit Score: 97.25  E-value: 4.75e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  15 HLLTAISFLIPIVCGSGFIIAIG--MGLGGTVQDTLTPGQFDVWQAMATLGAKALGLLPVVIAVGISGSIAGKPGIAPGF 92
Cdd:PRK11404  130 HLMAGVSAALPFVIGGGILVALAnmLVQFGLPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAF 209
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  93 VVGLAANTIS-------AGFIGGMIGGYIAGYIALAIiKNVKVPDWARGLMPTLIVPFFASIISCMIMVYIIGTPIGIFT 165
Cdd:PRK11404  210 LVCYLANDKAllgtqsgAGFLGAVVLGLAIGYFVFWF-RKVRLGKALQPLLGSMLIPFVTLLVFGVLTYYVIGPVMSDLM 288
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 166 EALTSFLRSMGTSSNFVLGAVIGALCIVDFGGPLNKTCFAFVLTLQAQGINEPITALQLVNTATPIGFGLAFFIakllRK 245
Cdd:PRK11404  289 GGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSLLEKHIYDWYAIVGVVALMPPVAAGLATFI----AP 364
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363 246 NIYNREEVETLKSAVPMGIVNIVEGSIPIVMNDIVRGIAAAAIGGACGGAVTMVYGADATVPFGGV------LMIPTMSH 319
Cdd:PRK11404  365 KLFTRQEKEAASSAIVVGATVATEPAIPYALAAPLPMITANTLAGGITGVLVIAFGIKRLAPGLGIfdpligLMSPVGSF 444
                         330
                  ....*....|..
gi 1513525363 320 PMAGIMALLVNI 331
Cdd:PRK11404  445 YLVLAIGLALNI 456
PtsG1 COG1263
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific ...
23-190 2.38e-05

Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism];


Pssm-ID: 440875 [Multi-domain]  Cd Length: 463  Bit Score: 46.09  E-value: 2.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  23 LIPIVCGSGFIIAIGMGLGGTVQDTLTPGQFDVWQAMATLGAKALGLLPVVIAVGISGSIAGKPGIA---------PGFV 93
Cdd:COG1263    22 PIPVLPAAGLLLGLGALLTNPGLLGEGSFLSGTYQILNAAGDAVFYFLPLLFAIGAAKGFGGNPALAavigyllvhPTLL 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  94 VGLAANTISAGFIG---------GMIGGYIAGYIALAIIK--NVKVPDWARglmpTLIVPFFASIISCMIMVYIIGTPIG 162
Cdd:COG1263   102 NAYAVAGGYISFLGiptligyqgGVFPGILAGWLAAYLEKflKKKLPDALG----FFFVPILTLLIMVPLALLVIGPIWP 177
                         170       180
                  ....*....|....*....|....*...
gi 1513525363 163 IFTEALTSFLRSMGTSSNFVLGAVIGAL 190
Cdd:COG1263   178 PIGNGIAAGLGWIYGLAGAIGGFIYGFL 205
PTS_EIIC pfam02378
Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase ...
19-191 1.73e-04

Phosphotransferase system, EIIC; The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). The IIC domain catalyzes the transfer of a phosphoryl group from IIB to the sugar substrate.


Pssm-ID: 367061  Cd Length: 315  Bit Score: 43.10  E-value: 1.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  19 AISFLIPIVCGSGFIIAIGMGLGGTVQDTLTPGQFDVWQA--MATLGAKALGLLPVVIAVGISGSIAG-KPGIAPGFVVG 95
Cdd:pfam02378   3 GFMPPIPLLIAGGILLGLGNLPNDTTGLPAGGFTGDSPLAeiLKQAGSAAFGILPILFAIGIAYGLAGgDGVAGAAGLIG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1513525363  96 LAA-------------------------NTISAGFIGGMIGGYIAGYIALAIIKNV--KVPDWARGLMPTLIVPFFASII 148
Cdd:pfam02378  83 LLSfnlaaaisvaltaaglsgggnilgiGLGATGVFGAIIPGLLAAYLYNRFEKNItiKLPDSLPFFVGKRFVPIITGFV 162
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1513525363 149 SCMIMVYIIGTPIGIFTEALTSFLRSMGTSSNFVLGAVIGALC 191
Cdd:pfam02378 163 TLLVIGPVLGLIWPAIQGGLNALGLLLIIAGGILGGLIFGFLE 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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