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Conserved domains on  [gi|1533120966|gb|RRV72871|]
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cation transporter [Stutzerimonas stutzeri]

Protein Classification

MnhF family protein( domain architecture ID 10006146)

MnhF family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MnhF COG2212
Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];
1-80 9.08e-14

Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];


:

Pssm-ID: 441814  Cd Length: 84  Bit Score: 60.12  E-value: 9.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533120966  1 MIETLLVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIMR 80
Cdd:COG2212    5 VLLIALALLALALLLALYRLIRGPTLADRVLALDTLGTNAVALLALLGILTGRPLYLDVALVLALLGFVGTVAFARFLER 84
 
Name Accession Description Interval E-value
MnhF COG2212
Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];
1-80 9.08e-14

Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441814  Cd Length: 84  Bit Score: 60.12  E-value: 9.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533120966  1 MIETLLVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIMR 80
Cdd:COG2212    5 VLLIALALLALALLLALYRLIRGPTLADRVLALDTLGTNAVALLALLGILTGRPLYLDVALVLALLGFVGTVAFARFLER 84
PRK12599 PRK12599
putative monovalent cation/H+ antiporter subunit F; Reviewed
 6-85 2.88e-12

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 237148  Cd Length: 91  Bit Score: 56.46  E-value: 2.88e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533120966  6 LVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIMRKGKKE 85
Cdd:PRK12599  12 AVLLVLALILSLYRVILGPTLPDRVVALDTLNTITVGIIAVLAAATGRPLYLDIAIVYALLSFLGTVAIAKYLVGRGGVL 91
MrpF_PhaF pfam04066
Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF ...
 28-79 7.89e-08

Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF family are predicted to be an integral membrane proteins with three transmembrane regions, involved in regulation of pH. PhaF is part of a potassium efflux system involved in pH regulation. It is also involved in symbiosis in Rhizobium meliloti. MrpF is part of a Na+/H+ antiporter complex, also involved in pH homeostasis. MrpF is thought to be an efflux system for Na+ and cholate. The Mrp system in Bacilli may also have primary energization capacities.


Pssm-ID: 461156  Cd Length: 52  Bit Score: 44.31  E-value: 7.89e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 1533120966 28 DRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIM 79
Cdd:pfam04066  1 DRVVALDTLGTNIVALLALLAILTGRPAYLDVALVLALLGFVGTVAFARFLE 52
 
Name Accession Description Interval E-value
MnhF COG2212
Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];
1-80 9.08e-14

Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441814  Cd Length: 84  Bit Score: 60.12  E-value: 9.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533120966  1 MIETLLVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIMR 80
Cdd:COG2212    5 VLLIALALLALALLLALYRLIRGPTLADRVLALDTLGTNAVALLALLGILTGRPLYLDVALVLALLGFVGTVAFARFLER 84
PRK12599 PRK12599
putative monovalent cation/H+ antiporter subunit F; Reviewed
 6-85 2.88e-12

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 237148  Cd Length: 91  Bit Score: 56.46  E-value: 2.88e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533120966  6 LVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIMRKGKKE 85
Cdd:PRK12599  12 AVLLVLALILSLYRVILGPTLPDRVVALDTLNTITVGIIAVLAAATGRPLYLDIAIVYALLSFLGTVAIAKYLVGRGGVL 91
MrpF_PhaF pfam04066
Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF ...
 28-79 7.89e-08

Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF family are predicted to be an integral membrane proteins with three transmembrane regions, involved in regulation of pH. PhaF is part of a potassium efflux system involved in pH regulation. It is also involved in symbiosis in Rhizobium meliloti. MrpF is part of a Na+/H+ antiporter complex, also involved in pH homeostasis. MrpF is thought to be an efflux system for Na+ and cholate. The Mrp system in Bacilli may also have primary energization capacities.


Pssm-ID: 461156  Cd Length: 52  Bit Score: 44.31  E-value: 7.89e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 1533120966 28 DRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIM 79
Cdd:pfam04066  1 DRVVALDTLGTNIVALLALLAILTGRPAYLDVALVLALLGFVGTVAFARFLE 52
PRK12600 PRK12600
Na(+)/H(+) antiporter subunit F1;
1-80 3.66e-07

Na(+)/H(+) antiporter subunit F1;


Pssm-ID: 183617  Cd Length: 94  Bit Score: 43.76  E-value: 3.66e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533120966  1 MIETLLVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIMR 80
Cdd:PRK12600   5 ILSIALIIVAISMLLMLIRVIKGPTLADRVVALDAIGINLIAIIALFSILLDTKAYLEVILLIGILAFIGTAAFSKFIEK 84
PRK06161 PRK06161
putative monovalent cation/H+ antiporter subunit F; Reviewed
 6-80 4.15e-06

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 180435  Cd Length: 89  Bit Score: 40.60  E-value: 4.15e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1533120966  6 LVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIMR 80
Cdd:PRK06161  10 QVALALAMLLALWRLLRGPRAQDRILALDTLYINAILLLLVFGIRLGSTIYFEAALLIALLGFVSTVALAKFLLR 84
PRK12657 PRK12657
putative monovalent cation/H+ antiporter subunit F; Reviewed
 1-78 1.31e-04

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 183657  Cd Length: 100  Bit Score: 37.05  E-value: 1.31e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1533120966   1 MIETLLVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFI 78
Cdd:PRK12657    9 MIISALIIFGIALIICLFRLIKGPTTADRVVTFDTTSAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSVSISRFI 86
PRK12604 PRK12604
putative monovalent cation/H+ antiporter subunit F; Reviewed
 1-78 7.47e-04

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 183619  Cd Length: 84  Bit Score: 34.74  E-value: 7.47e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1533120966  1 MIETLLVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFI 78
Cdd:PRK12604   3 GINIYLALIAIATLLSMYRVFRGPTTVDRLVAVDIMTTITTGLMVLFALYYKRMIFLDVALVYAILAFVGVIAFARYL 80
PRK12612 PRK12612
putative monovalent cation/H+ antiporter subunit F; Reviewed
 1-80 7.76e-03

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 237151  Cd Length: 87  Bit Score: 32.20  E-value: 7.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533120966  1 MIETLLVLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVFIMR 80
Cdd:PRK12612   5 ISEIFLIIILLVILLALVLIIRTKDILTRLVISDMVFYAMALILLCLGLYNGTSIYYDIALAAGLLGFLGTIAYARIISG 84
PRK07948 PRK07948
putative monovalent cation/H+ antiporter subunit F; Reviewed
 7-77 8.80e-03

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 181179  Cd Length: 86  Bit Score: 31.97  E-value: 8.80e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1533120966  7 VLVMLPLGVTLWRMIVARTLVDRVVALDMLTGVGVAIAALVAAMTGRREFLDVGFGLGLIGFVGTCAFAVF 77
Cdd:PRK07948  10 VFLSLAAILTTYRILAGPNSLDRLVALDTLVAVTMCALATWAAWTLDTTVTNAMTALALIGFIGSVSVARF 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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