|
Name |
Accession |
Description |
Interval |
E-value |
| NifS |
COG1104 |
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino ... |
1-378 |
0e+00 |
|
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino acid transport and metabolism];
Pssm-ID: 440721 [Multi-domain] Cd Length: 381 Bit Score: 570.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 1 MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAIL 80
Cdd:COG1104 1 MMMIYLDNAATTPVDPEVLEAMLPYLTEYFGNPSSLHSFGREARAALEEAREQVAALLGADPEEIIFTSGGTEANNLAIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 81 ETAFSRQKEGRHLITTAIEHPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK 160
Cdd:COG1104 81 GAARAYRKKGKHIITSAIEHPAVLETARFLEKEGFEVTYLPVDEDGRVDLEALEAALRPDTALVSVMHANNETGTIQPIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 161 EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGVNIPALLLGGEQEEKRRAGTENL 240
Cdd:COG1104 161 EIAEIAKEHGVLFHTDAVQAVGKIPVDVKELGVDLLSLSAHKIYGPKGVGALYVRKGVRLEPLIHGGGQERGLRSGTENV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 241 AGIWGMAKAVElLSSEEREARNNKYKGFQQLILDTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAI 320
Cdd:COG1104 241 PGIVGLGKAAE-LAAEELEEEAARLRALRDRLEEGLLAAIPGVVINGDPENRLPNTLNFSFPGVEGEALLLALDLAGIAV 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1533615239 321 STGSACTAGNIEPSHVLEAMyGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK 378
Cdd:COG1104 320 SSGSACSSGSLEPSHVLLAM-GLDEELAHGSIRFSLGRFTTEEEIDRAIEALKEIVAR 376
|
|
| FeS_nifS |
TIGR03402 |
cysteine desulfurase NifS; Members of this protein family are NifS, one of several related ... |
4-378 |
5.19e-156 |
|
cysteine desulfurase NifS; Members of this protein family are NifS, one of several related families of cysteine desulfurase involved in iron-sulfur (FeS) cluster biosynthesis. NifS is part of the NIF system, usually associated with other nif genes involved in nitrogenase expression and nitrogen fixation. The protein family is given a fairly broad interpretation here. It includes a clade nearly always found in extended nitrogen fixation genomic regions, plus a second clade more closely related to the first than to IscS and also part of NifS-like/NifU-like systems. This model does not extend to a more distantly clade found in the epsilon proteobacteria such as Helicobacter pylori, also named NifS in the literature, built instead in TIGR03403.
Pssm-ID: 132443 [Multi-domain] Cd Length: 379 Bit Score: 443.59 E-value: 5.19e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETA 83
Cdd:TIGR03402 1 IYLDNNATTRVDPEVLEAMLPYFTEYFGNPSSMHSFGGEVGKAVEEAREQVAKLLGAEPDEIIFTSGGTESDNTAIKSAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 84 FSrQKEGRHLITTAIEHPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIKEIG 163
Cdd:TIGR03402 81 AA-QPEKRHIITTAVEHPAVLSLCQHLEKQGYKVTYLPVDEEGRLDLEELRAAITDDTALVSVMWANNETGTIFPIEEIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 164 ELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGVNIPALLLGGEQEEKRRAGTENLAGI 243
Cdd:TIGR03402 160 EIAKERGALFHTDAVQAVGKIPIDLKEMNIDMLSLSGHKLHGPKGVGALYIRKGTRFRPLLRGGHQERGRRAGTENVPGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 244 WGMAKAVElLSSEEREARNNKYKGFQqlilDTLEA---NEIPY-QVNGDLTNKLPHVLNLRLI---GEAndlLLMKLDLN 316
Cdd:TIGR03402 240 VGLGKAAE-LATEHLEEENTRVRALR----DRLEAgllARIPDaRLNGDPTKRLPNTVNISFEyieGEA---ILLLLDME 311
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1533615239 317 GVAISTGSACTAGNIEPSHVLEAMyGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK 378
Cdd:TIGR03402 312 GICASSGSACTSGSLEPSHVLRAM-GVPHTAAHGSIRFSLSRYNTEEDIDYVLEVLPPIIAR 372
|
|
| PLN02651 |
PLN02651 |
cysteine desulfurase |
4-365 |
9.34e-122 |
|
cysteine desulfurase
Pssm-ID: 178257 [Multi-domain] Cd Length: 364 Bit Score: 356.27 E-value: 9.34e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSI-HGFGRHAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILET 82
Cdd:PLN02651 1 LYLDMQATTPIDPRVLDAMLPFLIEHFGNPHSRtHLYGWESEDAVEKARAQVAALIGADPKEIIFTSGATESNNLAIKGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 83 AFSRQKEGRHLITTAIEHPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIKEI 162
Cdd:PLN02651 81 MHFYKDKKKHVITTQTEHKCVLDSCRHLQQEGFEVTYLPVKSDGLVDLDELAAAIRPDTALVSVMAVNNEIGVIQPVEEI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 163 GELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLY--KRDGVNIPALLLGGEQEEKRRAGTENL 240
Cdd:PLN02651 161 GELCREKKVLFHTDAAQAVGKIPVDVDDLGVDLMSISGHKIYGPKGVGALYvrRRPRVRLEPLMSGGGQERGRRSGTENT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 241 AGIWGMAKAVELLsSEEREARNNKYKGFQQLILDTLEANEIPYQVNG--DLTNKLPHVLNLRLIGEANDLLLMKldLNGV 318
Cdd:PLN02651 241 PLVVGLGAACELA-MKEMDYDEKHMKALRERLLNGLRAKLGGVRVNGprDPEKRYPGTLNLSFAYVEGESLLMG--LKEV 317
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1533615239 319 AISTGSACTAGNIEPSHVLEAMyGEDTPILKESIRISFGLGNTEDDI 365
Cdd:PLN02651 318 AVSSGSACTSASLEPSYVLRAL-GVPEEMAHGSLRLGVGRFTTEEEV 363
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
4-368 |
1.91e-87 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 268.73 E-value: 1.91e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNP-SSIHGFGRHAHEKLETARQIIADSLQAK-PHEIIFNSGGTEGDNTAILe 81
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVhRGVHTLGKEATQAYEEAREKVAEFINAPsNDEIIFTSGTTEAINLVAL- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 82 TAFSRQKEGRHLITTAIEHPAVLNTMKYL-ETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK 160
Cdd:pfam00266 80 SLGRSLKPGDEIVITEMEHHANLVPWQELaKRTGARVRVLPLDEDGLLDLDELEKLITPKTKLVAITHVSNVTGTIQPVP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 161 EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRD--GVNIPALLLGG----------- 227
Cdd:pfam00266 160 EIGKLAHQYGALVLVDAAQAIGHRPIDVQKLGVDFLAFSGHKLYGPTGIGVLYGRRdlLEKMPPLLGGGgmietvslqes 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 228 ---EQEEKRRAGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLILDTLEANEIpYQVNGDLtnKLPHVLNLRLIGE 304
Cdd:pfam00266 240 tfaDAPWKFEAGTPNIAGIIGLGAALEYLSEIGLEAIEKHEHELAQYLYERLLSLPG-IRLYGPE--RRASIISFNFKGV 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1533615239 305 ANDLLLMKLDLNGVAISTGSACTagniEPSHVLEAMYGedtpilkeSIRISFGLGNTEDDIQYF 368
Cdd:pfam00266 317 HPHDVATLLDESGIAVRSGHHCA----QPLMVRLGLGG--------TVRASFYIYNTQEDVDRL 368
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
4-376 |
5.43e-56 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 187.67 E-value: 5.43e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNPS-SIHGFGRHAHEKLETARQIIADSLQAK-PHEIIFNSGGTEGDNTAILe 81
Cdd:cd06453 1 VYLDNAATSQKPQPVIDAIVDYYRHYNANVHrGVHELSARATDAYEAAREKVARFINAPsPDEIIFTRNTTEAINLVAY- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 82 tAFSRQ-KEGRHLITTAIEHPAVLNTMKYL-ETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPI 159
Cdd:cd06453 80 -GLGRAnKPGDEIVTSVMEHHSNIVPWQQLaERTGAKLKVVPVDDDGQLDLEALEKLLTERTKLVAVTHVSNVLGTINPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 160 KEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV--NIPALLLGGEQEE------ 231
Cdd:cd06453 159 KEIGEIAHEAGVPVLVDGAQSAGHMPVDVQDLGCDFLAFSGHKMLGPTGIGVLYGKEELleEMPPYGGGGEMIEevsfee 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 232 --------KRRAGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLILDTLEanEIPY-QVNGDLTNKLPhVLNLRLI 302
Cdd:cd06453 239 ttyadlphKFEAGTPNIAGAIGLGAAIDYLEKIGMEAIAAHEHELTAYALERLS--EIPGvRVYGDAEDRAG-VVSFNLE 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1533615239 303 GEANDLLLMKLDLNGVAISTGSACTagniEPSHvlEAMYgedtpiLKESIRISFGLGNTEDDIqyflDQLVRAV 376
Cdd:cd06453 316 GIHPHDVATILDQYGIAVRAGHHCA----QPLM--RRLG------VPGTVRASFGLYNTEEEI----DALVEAL 373
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NifS |
COG1104 |
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino ... |
1-378 |
0e+00 |
|
Cysteine desulfurase/Cysteine sulfinate desulfinase IscS or related enzyme, NifS family [Amino acid transport and metabolism];
Pssm-ID: 440721 [Multi-domain] Cd Length: 381 Bit Score: 570.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 1 MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAIL 80
Cdd:COG1104 1 MMMIYLDNAATTPVDPEVLEAMLPYLTEYFGNPSSLHSFGREARAALEEAREQVAALLGADPEEIIFTSGGTEANNLAIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 81 ETAFSRQKEGRHLITTAIEHPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK 160
Cdd:COG1104 81 GAARAYRKKGKHIITSAIEHPAVLETARFLEKEGFEVTYLPVDEDGRVDLEALEAALRPDTALVSVMHANNETGTIQPIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 161 EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGVNIPALLLGGEQEEKRRAGTENL 240
Cdd:COG1104 161 EIAEIAKEHGVLFHTDAVQAVGKIPVDVKELGVDLLSLSAHKIYGPKGVGALYVRKGVRLEPLIHGGGQERGLRSGTENV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 241 AGIWGMAKAVElLSSEEREARNNKYKGFQQLILDTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAI 320
Cdd:COG1104 241 PGIVGLGKAAE-LAAEELEEEAARLRALRDRLEEGLLAAIPGVVINGDPENRLPNTLNFSFPGVEGEALLLALDLAGIAV 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1533615239 321 STGSACTAGNIEPSHVLEAMyGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK 378
Cdd:COG1104 320 SSGSACSSGSLEPSHVLLAM-GLDEELAHGSIRFSLGRFTTEEEIDRAIEALKEIVAR 376
|
|
| FeS_nifS |
TIGR03402 |
cysteine desulfurase NifS; Members of this protein family are NifS, one of several related ... |
4-378 |
5.19e-156 |
|
cysteine desulfurase NifS; Members of this protein family are NifS, one of several related families of cysteine desulfurase involved in iron-sulfur (FeS) cluster biosynthesis. NifS is part of the NIF system, usually associated with other nif genes involved in nitrogenase expression and nitrogen fixation. The protein family is given a fairly broad interpretation here. It includes a clade nearly always found in extended nitrogen fixation genomic regions, plus a second clade more closely related to the first than to IscS and also part of NifS-like/NifU-like systems. This model does not extend to a more distantly clade found in the epsilon proteobacteria such as Helicobacter pylori, also named NifS in the literature, built instead in TIGR03403.
Pssm-ID: 132443 [Multi-domain] Cd Length: 379 Bit Score: 443.59 E-value: 5.19e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETA 83
Cdd:TIGR03402 1 IYLDNNATTRVDPEVLEAMLPYFTEYFGNPSSMHSFGGEVGKAVEEAREQVAKLLGAEPDEIIFTSGGTESDNTAIKSAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 84 FSrQKEGRHLITTAIEHPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIKEIG 163
Cdd:TIGR03402 81 AA-QPEKRHIITTAVEHPAVLSLCQHLEKQGYKVTYLPVDEEGRLDLEELRAAITDDTALVSVMWANNETGTIFPIEEIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 164 ELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGVNIPALLLGGEQEEKRRAGTENLAGI 243
Cdd:TIGR03402 160 EIAKERGALFHTDAVQAVGKIPIDLKEMNIDMLSLSGHKLHGPKGVGALYIRKGTRFRPLLRGGHQERGRRAGTENVPGI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 244 WGMAKAVElLSSEEREARNNKYKGFQqlilDTLEA---NEIPY-QVNGDLTNKLPHVLNLRLI---GEAndlLLMKLDLN 316
Cdd:TIGR03402 240 VGLGKAAE-LATEHLEEENTRVRALR----DRLEAgllARIPDaRLNGDPTKRLPNTVNISFEyieGEA---ILLLLDME 311
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1533615239 317 GVAISTGSACTAGNIEPSHVLEAMyGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK 378
Cdd:TIGR03402 312 GICASSGSACTSGSLEPSHVLRAM-GVPHTAAHGSIRFSLSRYNTEEDIDYVLEVLPPIIAR 372
|
|
| PLN02651 |
PLN02651 |
cysteine desulfurase |
4-365 |
9.34e-122 |
|
cysteine desulfurase
Pssm-ID: 178257 [Multi-domain] Cd Length: 364 Bit Score: 356.27 E-value: 9.34e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSI-HGFGRHAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILET 82
Cdd:PLN02651 1 LYLDMQATTPIDPRVLDAMLPFLIEHFGNPHSRtHLYGWESEDAVEKARAQVAALIGADPKEIIFTSGATESNNLAIKGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 83 AFSRQKEGRHLITTAIEHPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIKEI 162
Cdd:PLN02651 81 MHFYKDKKKHVITTQTEHKCVLDSCRHLQQEGFEVTYLPVKSDGLVDLDELAAAIRPDTALVSVMAVNNEIGVIQPVEEI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 163 GELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLY--KRDGVNIPALLLGGEQEEKRRAGTENL 240
Cdd:PLN02651 161 GELCREKKVLFHTDAAQAVGKIPVDVDDLGVDLMSISGHKIYGPKGVGALYvrRRPRVRLEPLMSGGGQERGRRSGTENT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 241 AGIWGMAKAVELLsSEEREARNNKYKGFQQLILDTLEANEIPYQVNG--DLTNKLPHVLNLRLIGEANDLLLMKldLNGV 318
Cdd:PLN02651 241 PLVVGLGAACELA-MKEMDYDEKHMKALRERLLNGLRAKLGGVRVNGprDPEKRYPGTLNLSFAYVEGESLLMG--LKEV 317
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1533615239 319 AISTGSACTAGNIEPSHVLEAMyGEDTPILKESIRISFGLGNTEDDI 365
Cdd:PLN02651 318 AVSSGSACTSASLEPSYVLRAL-GVPEEMAHGSLRLGVGRFTTEEEV 363
|
|
| DNA_S_dndA |
TIGR03235 |
cysteine desulfurase DndA; This model describes DndA, a protein related to IscS and part of a ... |
5-355 |
2.54e-118 |
|
cysteine desulfurase DndA; This model describes DndA, a protein related to IscS and part of a larger family of cysteine desulfurases. It is encoded, typically, divergently from a conserved, sparsely distributed operon for sulfur modification of DNA. This modification system is designated dnd, after the phenotype of DNA degradation during electrophoresis. The system is sporadically distributed in bacteria, much like some restriction enzyme operons. DndB is described as a putative ATPase. [DNA metabolism, Restriction/modification]
Pssm-ID: 163191 [Multi-domain] Cd Length: 353 Bit Score: 347.17 E-value: 2.54e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 5 YLDHAATTPMHPQVIEAMTAIMQDTFGNPSSI-HGFGRHAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETA 83
Cdd:TIGR03235 1 YLDHNATTPIDPAVAEAMLPWLLEEFGNPSSRtHEFGHNAKKAVERARKQVAEALGADTEEVIFTSGATESNNLAILGLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 84 -FSRQKEGRHLITTAIEHPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIKEI 162
Cdd:TIGR03235 81 rAGEQKGKKHIITSAIEHPAVLEPIRALERNGFTVTYLPVDESGRIDVDELADAIRPDTLLVSIMHVNNETGSIQPIREI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 163 GELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLY--KRDGVNIP--ALLLGGEQEEKRRAGTE 238
Cdd:TIGR03235 161 AEVLEAHEAFFHVDAAQVVGKITVDLSADRIDLISCSGHKIYGPKGIGALVirKRGKPKAPlkPIMFGGGQERGLRPGTL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 239 NLAGIWGMAKAVElLSSEEREARNNKYKGFQQLILDTLEANeiPYQVNGDLTNKLPHVLNLRLIGeANDLLLMKLDLNGV 318
Cdd:TIGR03235 241 PVHLIVGMGEAAE-IARRNAQAWEVKLRAMRNQLRDALQTL--GVKLNGDPAETIPHILNFSIDG-VNSEALIVNLRADA 316
|
330 340 350
....*....|....*....|....*....|....*..
gi 1533615239 319 AISTGSACTAGNIEPSHVLEAMyGEDTPILKESIRIS 355
Cdd:TIGR03235 317 AVSTGSACSSSKYEPSHVLQAM-GLDTDRARGAIRFS 352
|
|
| PRK14012 |
PRK14012 |
IscS subfamily cysteine desulfurase; |
1-378 |
5.13e-117 |
|
IscS subfamily cysteine desulfurase;
Pssm-ID: 184450 [Multi-domain] Cd Length: 404 Bit Score: 345.39 E-value: 5.13e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 1 MKT-IYLDHAATTPMHPQVIEAMTAIMQ--DTFGNPSS-IHGFGRHAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDN 76
Cdd:PRK14012 1 MKLpIYLDYSATTPVDPRVAEKMMPYLTmdGTFGNPASrSHRFGWQAEEAVDIARNQIADLIGADPREIVFTSGATESDN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 77 TAILETAFSRQKEGRHLITTAIEHPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNL 156
Cdd:PRK14012 81 LAIKGAAHFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLDPQSNGIIDLEKLEAAMRDDTILVSIMHVNNEIGVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 157 MPIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLY--KRDGVNIPALLLGGEQEEKRR 234
Cdd:PRK14012 161 QDIAAIGEICRERGIIFHVDAAQSVGKVPIDLSKLKVDLMSFSAHKIYGPKGIGALYvrRKPRVRLEAQMHGGGHERGMR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 235 AGTENLAGIWGMAKAVElLSSEEREARNNKYKGFQQLILDTLEANEIPYqVNGDLTNKLPHVLNLRLIGEANDLLLMKld 314
Cdd:PRK14012 241 SGTLPTHQIVGMGEAAR-IAKEEMATENERIRALRDRLWNGIKDIEEVY-LNGDLEQRVPGNLNVSFNYVEGESLIMA-- 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1533615239 315 LNGVAISTGSACTAGNIEPSHVLEAMyGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK 378
Cdd:PRK14012 317 LKDLAVSSGSACTSASLEPSYVLRAL-GLNDELAHSSIRFSLGRFTTEEEIDYAIELVRKSIGK 379
|
|
| PRK02948 |
PRK02948 |
IscS subfamily cysteine desulfurase; |
4-372 |
3.74e-97 |
|
IscS subfamily cysteine desulfurase;
Pssm-ID: 179511 [Multi-domain] Cd Length: 381 Bit Score: 293.94 E-value: 3.74e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETA 83
Cdd:PRK02948 2 IYLDYAATTPMSKEALQTYQKAASQYFGNESSLHDIGGTASSLLQVCRKTFAEMIGGEEQGIYFTSGGTESNYLAIQSLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 84 FSRQKEGRHLITTAIEHPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIKEIG 163
Cdd:PRK02948 82 NALPQNKKHIITTPMEHASIHSYFQSLESQGYTVTEIPVDKSGLIRLVDLERAITPDTVLASIQHANSEIGTIQPIAEIG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 164 ELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGVNIPALLLGGEQEEKRRAGTENLAGI 243
Cdd:PRK02948 162 ALLKKYNVLFHSDCVQTFGKLPIDVFEMGIDSLSVSAHKIYGPKGVGAVYINPQVRWKPVFPGTTHEKGFRPGTVNVPGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 244 WGMAKAVELLsSEEREARNNKYKGFQQLILDTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTG 323
Cdd:PRK02948 242 AAFLTAAENI-LKNMQEESLRFKELRSYFLEQIQTLPLPIEVEGHSTSCLPHIIGVTIKGIEGQYTMLECNRRGIAISTG 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1533615239 324 SACTAGNIEPSHVLEAMyGEDTPILKESIRISFGLGNTEDDIQYFLDQL 372
Cdd:PRK02948 321 SACQVGKQEPSKTMLAI-GKTYEEAKQFVRFSFGQQTTKDQIDTTIHAL 368
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
4-368 |
1.91e-87 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 268.73 E-value: 1.91e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNP-SSIHGFGRHAHEKLETARQIIADSLQAK-PHEIIFNSGGTEGDNTAILe 81
Cdd:pfam00266 1 IYLDSAATTQKPQEVLDAIQEYYTDYNGNVhRGVHTLGKEATQAYEEAREKVAEFINAPsNDEIIFTSGTTEAINLVAL- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 82 TAFSRQKEGRHLITTAIEHPAVLNTMKYL-ETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK 160
Cdd:pfam00266 80 SLGRSLKPGDEIVITEMEHHANLVPWQELaKRTGARVRVLPLDEDGLLDLDELEKLITPKTKLVAITHVSNVTGTIQPVP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 161 EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRD--GVNIPALLLGG----------- 227
Cdd:pfam00266 160 EIGKLAHQYGALVLVDAAQAIGHRPIDVQKLGVDFLAFSGHKLYGPTGIGVLYGRRdlLEKMPPLLGGGgmietvslqes 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 228 ---EQEEKRRAGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLILDTLEANEIpYQVNGDLtnKLPHVLNLRLIGE 304
Cdd:pfam00266 240 tfaDAPWKFEAGTPNIAGIIGLGAALEYLSEIGLEAIEKHEHELAQYLYERLLSLPG-IRLYGPE--RRASIISFNFKGV 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1533615239 305 ANDLLLMKLDLNGVAISTGSACTagniEPSHVLEAMYGedtpilkeSIRISFGLGNTEDDIQYF 368
Cdd:pfam00266 317 HPHDVATLLDESGIAVRSGHHCA----QPLMVRLGLGG--------TVRASFYIYNTQEDVDRL 368
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
4-378 |
3.61e-67 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 217.31 E-value: 3.61e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNPS-SIHGFGRHAHEKLETARQIIADSLQAK-PHEIIFNSGGTEGDNTAILe 81
Cdd:COG0520 17 VYLDNAATGQKPRPVIDAIRDYYEPYNANVHrGAHELSAEATDAYEAAREKVARFIGAAsPDEIIFTRGTTEAINLVAY- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 82 tAFSRQKEGRHLITTAIEHPAVLNTMKYL-ETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK 160
Cdd:COG0520 96 -GLGRLKPGDEILITEMEHHSNIVPWQELaERTGAEVRVIPLDEDGELDLEALEALLTPRTKLVAVTHVSNVTGTVNPVK 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 161 EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV--NIPALLLGGEQEEK------ 232
Cdd:COG0520 175 EIAALAHAHGALVLVDGAQSVPHLPVDVQALGCDFYAFSGHKLYGPTGIGVLYGKRELleALPPFLGGGGMIEWvsfdgt 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 233 ------RR--AGTENLAGIWGMAKAVELLSS------EEREARNNKY--KGFQQL----ILDTleaneipyqvnGDLTNK 292
Cdd:COG0520 255 tyadlpRRfeAGTPNIAGAIGLGAAIDYLEAigmeaiEARERELTAYalEGLAAIpgvrILGP-----------ADPEDR 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 293 LPhVLNLRLIGEANDLLLMKLDLNGVAISTGSACTagniepsHVLEAMYGedtpiLKESIRISFGLGNTEDDIqyflDQL 372
Cdd:COG0520 324 SG-IVSFNVDGVHPHDVAALLDDEGIAVRAGHHCA-------QPLMRRLG-----VPGTVRASFHLYNTEEEI----DRL 386
|
....*.
gi 1533615239 373 VRAVKK 378
Cdd:COG0520 387 VEALKK 392
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
4-376 |
5.43e-56 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 187.67 E-value: 5.43e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGNPS-SIHGFGRHAHEKLETARQIIADSLQAK-PHEIIFNSGGTEGDNTAILe 81
Cdd:cd06453 1 VYLDNAATSQKPQPVIDAIVDYYRHYNANVHrGVHELSARATDAYEAAREKVARFINAPsPDEIIFTRNTTEAINLVAY- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 82 tAFSRQ-KEGRHLITTAIEHPAVLNTMKYL-ETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPI 159
Cdd:cd06453 80 -GLGRAnKPGDEIVTSVMEHHSNIVPWQQLaERTGAKLKVVPVDDDGQLDLEALEKLLTERTKLVAVTHVSNVLGTINPV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 160 KEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV--NIPALLLGGEQEE------ 231
Cdd:cd06453 159 KEIGEIAHEAGVPVLVDGAQSAGHMPVDVQDLGCDFLAFSGHKMLGPTGIGVLYGKEELleEMPPYGGGGEMIEevsfee 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 232 --------KRRAGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLILDTLEanEIPY-QVNGDLTNKLPhVLNLRLI 302
Cdd:cd06453 239 ttyadlphKFEAGTPNIAGAIGLGAAIDYLEKIGMEAIAAHEHELTAYALERLS--EIPGvRVYGDAEDRAG-VVSFNLE 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1533615239 303 GEANDLLLMKLDLNGVAISTGSACTagniEPSHvlEAMYgedtpiLKESIRISFGLGNTEDDIqyflDQLVRAV 376
Cdd:cd06453 316 GIHPHDVATILDQYGIAVRAGHHCA----QPLM--RRLG------VPGTVRASFGLYNTEEEI----DALVEAL 373
|
|
| PLN02855 |
PLN02855 |
Bifunctional selenocysteine lyase/cysteine desulfurase |
2-372 |
2.23e-29 |
|
Bifunctional selenocysteine lyase/cysteine desulfurase
Pssm-ID: 215460 [Multi-domain] Cd Length: 424 Bit Score: 117.54 E-value: 2.23e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 2 KTIYLDHAATTPMHPQVIEAMTAIMQDTFGN-PSSIHGFGRHAHEKLETARQIIADSLQAK-PHEIIFNSGGTEGDNTAI 79
Cdd:PLN02855 32 KLVYLDNAATSQKPAAVLDALQDYYEEYNSNvHRGIHALSAKATDAYELARKKVAAFINAStSREIVFTRNATEAINLVA 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 80 LETAFSRQKEGRHLITTAIEHPAVLNTMKYL-ETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMP 158
Cdd:PLN02855 112 YTWGLANLKPGDEVILSVAEHHSNIVPWQLVaQKTGAVLKFVGLTPDEVLDVEQLKELLSEKTKLVATHHVSNVLGSILP 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 159 IKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV--NIPALLLGGE-------- 228
Cdd:PLN02855 192 VEDIVHWAHAVGAKVLVDACQSVPHMPVDVQTLGADFLVASSHKMCGPTGIGFLWGKSDLleSMPPFLGGGEmisdvfld 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 229 ----QEEKRR--AGTENLAGIWGMAKAVELLSseerearnnkykgfqQLILDTLEANEIpyQVNGDLTNKLPHVLNLRLI 302
Cdd:PLN02855 272 hstyAPPPSRfeAGTPAIGEAIGLGAAIDYLS---------------EIGMDRIHEYEV--ELGTYLYEKLSSVPGVRIY 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 303 G--------------------EANDLLLMkLDL-NGVAISTGSACTagniEPSHvleAMYGedtpiLKESIRISFGLGNT 361
Cdd:PLN02855 335 GpkpsegvgraalcafnvegiHPTDLSTF-LDQqHGVAIRSGHHCA----QPLH---RYLG-----VNASARASLYFYNT 401
|
410
....*....|.
gi 1533615239 362 EDDIQYFLDQL 372
Cdd:PLN02855 402 KEEVDAFIHAL 412
|
|
| PRK09295 |
PRK09295 |
cysteine desulfurase SufS; |
4-378 |
5.76e-24 |
|
cysteine desulfurase SufS;
Pssm-ID: 181766 [Multi-domain] Cd Length: 406 Bit Score: 102.14 E-value: 5.76e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 4 IYLDHAATTPMHPQVIEAMTAIMQDTFGN-PSSIHGFGRHAHEKLETARQIIADSLQAK-PHEIIFNSGGTEGDNTAILE 81
Cdd:PRK09295 25 AYLDSAASAQKPSQVIDAEAEFYRHGYAAvHRGIHTLSAQATEKMENVRKQAALFINARsAEELVFVRGTTEGINLVANS 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 82 TAFSRQKEGRHLITTAIEHPAVLNTMKYL-ETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK 160
Cdd:PRK09295 105 WGNSNVRAGDNIIISEMEHHANIVPWQMLcARVGAELRVIPLNPDGTLQLETLPALFDERTRLLAITHVSNVLGTENPLA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 161 EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV--NIPALLLGG----------- 227
Cdd:PRK09295 185 EMIALAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALlqEMPPWEGGGsmiatvslteg 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 228 ----EQEEKRRAGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLILDTLEAneipyqvngdltnklphVLNLRLIG 303
Cdd:PRK09295 265 ttwaKAPWRFEAGTPNTGGIIGLGAALDYVSALGLNNIAEYEQNLMHYALSQLES-----------------VPDLTLYG 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 304 EANDLLLMK--------------LDLNGVAISTGSACTAGNIEPSHVlEAMygedtpilkesIRISFGLGNTEDDIqyfl 369
Cdd:PRK09295 328 PQNRLGVIAfnlgkhhaydvgsfLDNYGIAVRTGHHCAMPLMAYYNV-PAM-----------CRASLAMYNTHEEV---- 391
|
....*....
gi 1533615239 370 DQLVRAVKK 378
Cdd:PRK09295 392 DRLVAGLQR 400
|
|
| PRK10874 |
PRK10874 |
cysteine desulfurase CsdA; |
3-378 |
9.22e-17 |
|
cysteine desulfurase CsdA;
Pssm-ID: 182799 [Multi-domain] Cd Length: 401 Bit Score: 80.85 E-value: 9.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 3 TIYLDHAATTpMHPQ-VIEAMTAIMQDTFGN-PSSIHGFGRHAHEKLETARQIIADSLQA-KPHEIIFNSGGTEGDNTAI 79
Cdd:PRK10874 20 GVYLDSAATA-LKPQaVIEATQQFYSLSAGNvHRSQFAAAQRLTARYEAAREQVAQLLNApDAKNIVWTRGTTESINLVA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 80 LETAFSRQKEGRHLITTAIEHPAvlNTMKYL---ETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNL 156
Cdd:PRK10874 99 QSYARPRLQPGDEIIVSEAEHHA--NLVPWLmvaQQTGAKVVKLPLGADRLPDVDLLPELITPRTRILALGQMSNVTGGC 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 157 MPIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLY-KRDGVN-IPALLLGG------- 227
Cdd:PRK10874 177 PDLARAITLAHQAGMVVMVDGAQGAVHFPADVQALDIDFYAFSGHKLYGPTGIGVLYgKSELLEaMSPWQGGGkmltevs 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 228 -----EQEEKRR--AGTENLAGIWGMAKAVELLSSEEREARNNKYKGFQQLILDTLEaneipyQVNGDLTNKLPH--VLN 298
Cdd:PRK10874 257 fdgftPQSAPWRfeAGTPNVAGVIGLSAALEWLADIDINQAESWSRSLATLAEDALA------KLPGFRSFRCQDssLLA 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 299 LRLIGEANDLLLMKLDLNGVAISTGSACTagniEPshvLEAMYGedtpiLKESIRISFGLGNTEDDIqyflDQLVRAVKK 378
Cdd:PRK10874 331 FDFAGVHHSDLVTLLAEYGIALRAGQHCA----QP---LLAALG-----VTGTLRASFAPYNTQSDV----DALVNAVDR 394
|
|
| AGAT_like |
cd06451 |
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate ... |
114-212 |
7.31e-11 |
|
Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), serine-glyoxylate aminotransferase (SGAT), and 3-hydroxykynurenine transaminase (HKT). AGAT is a homodimeric protein, which catalyses the transamination of glyoxylate to glycine, and SGAT converts serine and glyoxylate to hydroxypyruvate and glycine. HKT catalyzes the PLP-dependent transamination of 3-hydroxykynurenine, a potentially toxic metabolite of the kynurenine pathway.
Pssm-ID: 99744 [Multi-domain] Cd Length: 356 Bit Score: 63.08 E-value: 7.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 114 GFDVTYLPVDEKGNLSIEEVKKALREDTI-LVSVMYGNNEIGNLMPIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELG 192
Cdd:cd06451 97 GADVDVVEKPWGEAVSPEEIAEALEQHDIkAVTLTHNETSTGVLNPLEGIGALAKKHDALLIVDAVSSLGGEPFRMDEWG 176
|
90 100
....*....|....*....|.
gi 1533615239 193 IDLLSISAHK-INGPKGVGFL 212
Cdd:cd06451 177 VDVAYTGSQKaLGAPPGLGPI 197
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
46-215 |
2.27e-10 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 58.93 E-value: 2.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 46 KLETARQIIADSLQAKPHEIIFNSGGTEGDNTAiLETAFSRqkeGRHLITTAIEHPAVLNTMkyLETKGFDVTYLPVDE- 124
Cdd:cd01494 1 KLEELEEKLARLLQPGNDKAVFVPSGTGANEAA-LLALLGP---GDEVIVDANGHGSRYWVA--AELAGAKPVPVPVDDa 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 125 -KGNLSIEEVKKALREDTI-LVSVMYGNNEIGNLMPIKEIGELLADHPAYFHTDAVQAYGNQT---IHPEELGIDLLSIS 199
Cdd:cd01494 75 gYGGLDVAILEELKAKPNVaLIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGASPapgVLIPEGGADVVTFS 154
|
170
....*....|....*.
gi 1533615239 200 AHKINGPKGVGFLYKR 215
Cdd:cd01494 155 LHKNLGGEGGGVVIVK 170
|
|
| PucG |
COG0075 |
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism ... |
114-266 |
7.06e-09 |
|
Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG [Amino acid transport and metabolism, Nucleotide transport and metabolism]; Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG is part of the Pathway/BioSystem: Serine biosynthesis
Pssm-ID: 439845 [Multi-domain] Cd Length: 376 Bit Score: 57.02 E-value: 7.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 114 GFDVTYLPVDEKGNLSIEEVKKALREDTI--LVSVMYgnNE--IGNLMPIKEIGELLADHPAYFHTDAVQAYGNQTIHPE 189
Cdd:COG0075 97 GAEVVVLEVPWGEAVDPEEVEEALAADPDikAVAVVH--NEtsTGVLNPLEEIGALAKEHGALLIVDAVSSLGGVPLDMD 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 190 ELGIDLLSISAHK-INGPKGVGFLY-------KRDGVNIPAL-----LLGGEQEEKRRAGTENLAGIWGMAKAVELLSSE 256
Cdd:COG0075 175 EWGIDVVVSGSQKcLMLPPGLAFVAvseraleAIEARKLPSYyldlkLWLKYWEKGQTPYTPPVSLLYALREALDLILEE 254
|
170
....*....|
gi 1533615239 257 EREARNNKYK 266
Cdd:COG0075 255 GLENRFARHR 264
|
|
| PLN02724 |
PLN02724 |
Molybdenum cofactor sulfurase |
2-146 |
1.54e-06 |
|
Molybdenum cofactor sulfurase
Pssm-ID: 215384 [Multi-domain] Cd Length: 805 Bit Score: 50.25 E-value: 1.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 2 KTIYLDHA-ATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAHEKLETARQIIADSLQAKPHE--IIFNSGGTEGdnTA 78
Cdd:PLN02724 34 GVVYLDHAgATLYSESQLEAALADFSSNVYGNPHSQSDSSMRSSDTIESARQQVLEYFNAPPSDyaCVFTSGATAA--LK 111
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1533615239 79 ILETAFSRQKEGRHLITTAiEHPAVLNTMKYLETKGfdVTYLPVDekgnlsIEEVKKALREDTILVSV 146
Cdd:PLN02724 112 LVGETFPWSSESHFCYTLE-NHNSVLGIREYALEKG--AAAIAVD------IEEAANQPTNSQGSVVV 170
|
|
| DOPA_deC_like |
cd06450 |
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
66-214 |
1.60e-06 |
|
DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.
Pssm-ID: 99743 [Multi-domain] Cd Length: 345 Bit Score: 49.51 E-value: 1.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 66 IFNSGGTEGDNTAIL---ETAFSRQKEGRHLITTAIE-------HPAVLNTMKYLETKgfdVTYLPVDEKGNLSIEEVKK 135
Cdd:cd06450 61 VFTSGGSESNLLALLaarDRARKRLKAGGGRGIDKLVivcsdqaHVSVEKAAAYLDVK---VRLVPVDEDGRMDPEALEA 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 136 ALRED------TILVSVMYGNNEIGNLMPIKEIGELLADHPAYFHTDAvqAYGNQTI---HPEEL--GI---DLLSISAH 201
Cdd:cd06450 138 AIDEDkaeglnPIMVVATAGTTDTGAIDPLEEIADLAEKYDLWLHVDA--AYGGFLLpfpEPRHLdfGIervDSISVDPH 215
|
170
....*....|....*
gi 1533615239 202 KING-PKGVG-FLYK 214
Cdd:cd06450 216 KYGLvPLGCSaVLVR 230
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
13-172 |
3.62e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 38.97 E-value: 3.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 13 PMHPQVIEAM-TAIMQDTFGNPSSIHGFgrhaheklETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAfsrqKEGR 91
Cdd:PRK06225 41 GPHEEVREAMiRCIEEGEYCKYPPPEGF--------PELRELILKDLGLDDDEALITAGATESLYLVMRAFL----SPGD 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1533615239 92 HLITTaieHPAVLNTMKYLETKGFDVTYLPV-DEKGN--LSIEEVKKALREDTILVSVMYGNNEIGNLMP---IKEIGEL 165
Cdd:PRK06225 109 NAVTP---DPGYLIIDNFASRFGAEVIEVPIySEECNykLTPELVKENMDENTRLIYLIDPLNPLGSSYTeeeIKEFAEI 185
|
....*..
gi 1533615239 166 LADHPAY 172
Cdd:PRK06225 186 ARDNDAF 192
|
|
| |
