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Conserved domains on  [gi|1538531800|gb|RTD85837|]
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FAD-binding oxidoreductase [Variovorax sp. 369]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11429741)

FAD/NAD(P)-binding oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.30.9.10
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660
SCOP:  3000055

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
11-370 1.11e-65

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


:

Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 212.84  E-value: 1.11e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  11 ADFLVIGGGIAGASVAHWLAPH-ARVILLEREsQPGYHSTGRSAALFMESYGTAQVRALTMASRAFLEHPPEGFSEHPL- 88
Cdd:COG0665     3 ADVVVIGGGIAGLSTAYHLARRgLDVTVLERG-RPGSGASGRNAGQLRPGLAALADRALVRLAREALDLWRELAAELGId 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  89 --LTPRGAMMVA-GAEHMAELEAHWEVLRAMDTGASRLSGEQAREMVPALRPEQVLGAVYEPDAADMDVHAIHQGYLRGM 165
Cdd:COG0665    82 cdFRRTGVLYLArTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARAA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 166 RRAGGRLVCDAGVTAIERVGERWR-VEAGGSVYEAPVVLNAAGAWVDTIARMAGVpPLGIEPRRRSAFIFAPPEGQsvAH 244
Cdd:COG0665   162 RAAGVRIREGTPVTGLEREGGRVTgVRTERGTVRADAVVLAAGAWSARLLPMLGL-RLPLRPVRGYVLVTEPLPDL--PL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 245 WPMVFgaDEGWYIKPDA--GMLLGspANADPVEPQDVQPEEMDIAIAMHRIEEATTLSIRRPTRTWAGLRSFVPDGDLVG 322
Cdd:COG0665   239 RPVLD--DTGVYLRPTAdgRLLVG--GTAEPAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPII 314

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1538531800 323 GFEPGMPGFFWVAAQGGYGIQTSAAMGEACAALARGLPLPERIASFGL 370
Cdd:COG0665   315 GRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSP 362
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
11-370 1.11e-65

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 212.84  E-value: 1.11e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  11 ADFLVIGGGIAGASVAHWLAPH-ARVILLEREsQPGYHSTGRSAALFMESYGTAQVRALTMASRAFLEHPPEGFSEHPL- 88
Cdd:COG0665     3 ADVVVIGGGIAGLSTAYHLARRgLDVTVLERG-RPGSGASGRNAGQLRPGLAALADRALVRLAREALDLWRELAAELGId 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  89 --LTPRGAMMVA-GAEHMAELEAHWEVLRAMDTGASRLSGEQAREMVPALRPEQVLGAVYEPDAADMDVHAIHQGYLRGM 165
Cdd:COG0665    82 cdFRRTGVLYLArTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARAA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 166 RRAGGRLVCDAGVTAIERVGERWR-VEAGGSVYEAPVVLNAAGAWVDTIARMAGVpPLGIEPRRRSAFIFAPPEGQsvAH 244
Cdd:COG0665   162 RAAGVRIREGTPVTGLEREGGRVTgVRTERGTVRADAVVLAAGAWSARLLPMLGL-RLPLRPVRGYVLVTEPLPDL--PL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 245 WPMVFgaDEGWYIKPDA--GMLLGspANADPVEPQDVQPEEMDIAIAMHRIEEATTLSIRRPTRTWAGLRSFVPDGDLVG 322
Cdd:COG0665   239 RPVLD--DTGVYLRPTAdgRLLVG--GTAEPAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPII 314

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1538531800 323 GFEPGMPGFFWVAAQGGYGIQTSAAMGEACAALARGLPLPERIASFGL 370
Cdd:COG0665   315 GRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSP 362
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 12-355 4.60e-53

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 179.13  E-value: 4.60e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  12 DFLVIGGGIAGASVAHWLA-PHARVILLERESQPGYHSTGRSAALFM---ESYGTAQVRALTMASRAFLEHPPEGFSEHP 87
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELArRGLSVTLLERGDDPGSGASGRNAGLIHpglRYLEPSELARLALEALDLWEELEEELGIDC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  88 LLTPRGAMMVAGAEHMAELEAHWEVLRAMDTGASRLSGEQAREMVPALRPeqVLGAVYEPDAADMDVHAIHQGYLRGMRR 167
Cdd:pfam01266  81 GFRRCGVLVLARDEEEEALEKLLAALRRLGVPAELLDAEELRELEPLLPG--LRGGLFYPDGGHVDPARLLRALARAAEA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 168 AGGRLVCDAGVTAIERVGERWRVEAGGsvyEAPVVLNAAGAWVDtIARMAGVPPLgIEPRRRSAFIFAP-PEGQSVAHWP 246
Cdd:pfam01266 159 LGVRIIEGTEVTGIEEEGGVWGVVTTG---EADAVVNAAGAWAD-LLALPGLRLP-VRPVRGQVLVLEPlPEALLILPVP 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 247 MVFGADEGWYIKPDAG--MLLGSPANADPVEPQDVQPEEMDIAiamhrIEEATTL--SIRRPTRTWAGLRSFvPDGDLVG 322
Cdd:pfam01266 234 ITVDPGRGVYLRPRADgrLLLGGTDEEDGFDDPTPDPEEIEEL-----LEAARRLfpALADIERAWAGLRPL-PDGLPII 307

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1538531800 323 GfEPGMPGFFWVAAQGGYGIQTSAAMGEACAAL 355
Cdd:pfam01266 308 G-RPGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
12-221 1.67e-21

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 94.89  E-value: 1.67e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  12 DFLVIGGGIAGASVAHWLA---PHARVILLERESQPGYHSTGRS-----AALFME------SYGTAQVRALtmasRAFLE 77
Cdd:PRK11728    4 DFVIIGGGIVGLSTAMQLQeryPGARIAVLEKESGPARHQTGHNsgvihAGVYYTpgslkaRFCRRGNEAT----KAFCD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  78 hppegfsEHPLLTPR-GAMMVA-GAEHMAELEAHWEvlRAMDTG--ASRLSGEQAREMVPALRPeqvLGAVYEPDAADMD 153
Cdd:PRK11728   80 -------QHGIPYEEcGKLLVAtSELELERMEALYE--RARANGieVERLDAEELREREPNIRG---LGAIFVPSTGIVD 147

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1538531800 154 VHAIHQGYLRGMRRAGGRLVCDAGVTAIERVGERWRVEAGGSVYEAPVVLNAAGAWVDTIARMAGVPP 221
Cdd:PRK11728  148 YRAVAEAMAELIQARGGEIRLGAEVTALDEHANGVVVRTTQGEYEARTLINCAGLMSDRLAKMAGLEP 215
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 12-378 1.26e-06

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 49.83  E-value: 1.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  12 DFLVIGGGIAGASVAHWLAPHA-RVILLERESQPgyHSTGRS-------AALFMESYGTaqvralTMASRAF-LEHPPEG 82
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGkKTLLLEQFDLP--HSRGSShgqsriiRKAYPEDFYT------PMMLECYqLWAQLEK 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  83 FSEHPLLTPRGaMMVAGAEHMAELEAHWEVLRAMDTGASRLSGEQAREMVPALR-PEQVLGaVYEPDA----ADMDVHAi 157
Cdd:TIGR01377  74 EAGTKLHRQTG-LLLLGPKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRvPRNEVG-LLDPNGgvlyAEKALRA- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 158 hqgyLRGMRRAGGRLVCD-AGVTAIERVGERWRVEAGGSVYEAPVVLNAAGAWVDTIARMAGVpPLGIEPRRRSAFIFAP 236
Cdd:TIGR01377 151 ----LQELAEAHGATVRDgTKVVEIEPTELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGI-EIPLQPLRINVCYWRE 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 237 PEGQS---VAHWP--MVFGADEGWYIKPD---AGMLLGSPANADPVEPQDVQPEE----MDIAIAMHRIEEATTLSIRRP 304
Cdd:TIGR01377 226 KEPGSygvSQAFPcfLVLGLNPHIYGLPSfeyPGLMKVYYHHGQQIDPDERDCPFgadiEDVQILRKFVRDHLPGLNGEP 305

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1538531800 305 TRTWAGLRSFVPDGDLVGGFEPGMPGFFWVAAQGGYGIQTSAAMGEACAALARGLPLPERIASFGLTAEMLGPQ 378
Cdd:TIGR01377 306 KKGEVCMYTNTPDEHFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFALKKK 379
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
11-370 1.11e-65

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 212.84  E-value: 1.11e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  11 ADFLVIGGGIAGASVAHWLAPH-ARVILLEREsQPGYHSTGRSAALFMESYGTAQVRALTMASRAFLEHPPEGFSEHPL- 88
Cdd:COG0665     3 ADVVVIGGGIAGLSTAYHLARRgLDVTVLERG-RPGSGASGRNAGQLRPGLAALADRALVRLAREALDLWRELAAELGId 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  89 --LTPRGAMMVA-GAEHMAELEAHWEVLRAMDTGASRLSGEQAREMVPALRPEQVLGAVYEPDAADMDVHAIHQGYLRGM 165
Cdd:COG0665    82 cdFRRTGVLYLArTEAELAALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARAA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 166 RRAGGRLVCDAGVTAIERVGERWR-VEAGGSVYEAPVVLNAAGAWVDTIARMAGVpPLGIEPRRRSAFIFAPPEGQsvAH 244
Cdd:COG0665   162 RAAGVRIREGTPVTGLEREGGRVTgVRTERGTVRADAVVLAAGAWSARLLPMLGL-RLPLRPVRGYVLVTEPLPDL--PL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 245 WPMVFgaDEGWYIKPDA--GMLLGspANADPVEPQDVQPEEMDIAIAMHRIEEATTLSIRRPTRTWAGLRSFVPDGDLVG 322
Cdd:COG0665   239 RPVLD--DTGVYLRPTAdgRLLVG--GTAEPAGFDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPII 314

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 1538531800 323 GFEPGMPGFFWVAAQGGYGIQTSAAMGEACAALARGLPLPERIASFGL 370
Cdd:COG0665   315 GRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSP 362
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 12-355 4.60e-53

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 179.13  E-value: 4.60e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  12 DFLVIGGGIAGASVAHWLA-PHARVILLERESQPGYHSTGRSAALFM---ESYGTAQVRALTMASRAFLEHPPEGFSEHP 87
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELArRGLSVTLLERGDDPGSGASGRNAGLIHpglRYLEPSELARLALEALDLWEELEEELGIDC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  88 LLTPRGAMMVAGAEHMAELEAHWEVLRAMDTGASRLSGEQAREMVPALRPeqVLGAVYEPDAADMDVHAIHQGYLRGMRR 167
Cdd:pfam01266  81 GFRRCGVLVLARDEEEEALEKLLAALRRLGVPAELLDAEELRELEPLLPG--LRGGLFYPDGGHVDPARLLRALARAAEA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 168 AGGRLVCDAGVTAIERVGERWRVEAGGsvyEAPVVLNAAGAWVDtIARMAGVPPLgIEPRRRSAFIFAP-PEGQSVAHWP 246
Cdd:pfam01266 159 LGVRIIEGTEVTGIEEEGGVWGVVTTG---EADAVVNAAGAWAD-LLALPGLRLP-VRPVRGQVLVLEPlPEALLILPVP 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 247 MVFGADEGWYIKPDAG--MLLGSPANADPVEPQDVQPEEMDIAiamhrIEEATTL--SIRRPTRTWAGLRSFvPDGDLVG 322
Cdd:pfam01266 234 ITVDPGRGVYLRPRADgrLLLGGTDEEDGFDDPTPDPEEIEEL-----LEAARRLfpALADIERAWAGLRPL-PDGLPII 307

                         330       340       350
                  ....*....|....*....|....*....|...
gi 1538531800 323 GfEPGMPGFFWVAAQGGYGIQTSAAMGEACAAL 355
Cdd:pfam01266 308 G-RPGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
12-237 3.33e-34

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 131.04  E-value: 3.33e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  12 DFLVIGGGIAGASVAHWLA--PHARVILLERESQPGYHSTGRSAAL----FMESYGTAQVRALTMASRAFLEhppegFS- 84
Cdd:COG0579     6 DVVIIGAGIVGLALARELSryEDLKVLVLEKEDDVAQESSGNNSGVihagLYYTPGSLKARLCVEGNELFYE-----LCr 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  85 EHPL-LTPRGAMMVA-GAEHMAELEAHWEVLRAMD-TGASRLSGEQAREMVPALRPEqVLGAVYEPDAADMDVHAIHQGY 161
Cdd:COG0579    81 ELGIpFKRCGKLVVAtGEEEVAFLEKLYERGKANGvPGLEILDREELRELEPLLSDE-GVAALYSPSTGIVDPGALTRAL 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1538531800 162 LRGMRRAGGRLVCDAGVTAIERVGERWRVEAGGSVYEAPVVLNAAGAWVDTIARMAGV-PPLGIEPRRRSAFIFAPP 237
Cdd:COG0579   160 AENAEANGVELLLNTEVTGIEREGDGWEVTTNGGTIRARFVINAAGLYADRLAQMAGIgKDFGIFPVKGEYLVLDKP 236
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
12-221 1.67e-21

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 94.89  E-value: 1.67e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  12 DFLVIGGGIAGASVAHWLA---PHARVILLERESQPGYHSTGRS-----AALFME------SYGTAQVRALtmasRAFLE 77
Cdd:PRK11728    4 DFVIIGGGIVGLSTAMQLQeryPGARIAVLEKESGPARHQTGHNsgvihAGVYYTpgslkaRFCRRGNEAT----KAFCD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  78 hppegfsEHPLLTPR-GAMMVA-GAEHMAELEAHWEvlRAMDTG--ASRLSGEQAREMVPALRPeqvLGAVYEPDAADMD 153
Cdd:PRK11728   80 -------QHGIPYEEcGKLLVAtSELELERMEALYE--RARANGieVERLDAEELREREPNIRG---LGAIFVPSTGIVD 147

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1538531800 154 VHAIHQGYLRGMRRAGGRLVCDAGVTAIERVGERWRVEAGGSVYEAPVVLNAAGAWVDTIARMAGVPP 221
Cdd:PRK11728  148 YRAVAEAMAELIQARGGEIRLGAEVTALDEHANGVVVRTTQGEYEARTLINCAGLMSDRLAKMAGLEP 215
solA PRK11259
N-methyl-L-tryptophan oxidase;
123-370 2.62e-10

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 61.39  E-value: 2.62e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 123 LSGEQAREMVPALRPEQVLGAVYEPDAADMDVHAIHQGYLRGMRRAGGRLVCDAGVTAIERVGERWRVEAGGSVYEAPVV 202
Cdd:PRK11259  117 LDAAEIRRRFPQFRLPDGYIALFEPDGGFLRPELAIKAHLRLAREAGAELLFNEPVTAIEADGDGVTVTTADGTYEAKKL 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 203 LNAAGAWVDTIARMAGVPplgIEPRRRSAFIFAPPEGQS-VAHWPmVFGADEgwyikPDAGMLLGSPANADPvepqdvqp 281
Cdd:PRK11259  197 VVSAGAWVKDLLPPLELP---LTPVRQVLAWFQADGRYSePNRFP-AFIWEV-----PDGDQYYGFPAENGP-------- 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 282 eemDIAIAMHR-IEEATTLSIRRPTRTWAG----LRSFV---------------------PDGDLVGGFEPGMPGFFWVA 335
Cdd:PRK11259  260 ---GLKIGKHNgGQEITSPDERDRFVTVAEdgaeLRPFLrnylpgvgpclrgaactytntPDEHFIIDTLPGHPNVLVAS 336

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 1538531800 336 AQGGYGIQTSAAMGEACAALARGLPLPERIASFGL 370
Cdd:PRK11259  337 GCSGHGFKFASVLGEILADLAQDGTSDFDLSPFSL 371
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 5-220 3.97e-07

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 52.16  E-value: 3.97e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800   5 TAEPVVADFLVIGGGIAGASVAHWLAPH-ARVILLERESQPGYHSTG-RSAALF--MESYGTAQVR----ALTMASRAF- 75
Cdd:PRK01747  255 PGSPKARDAAIIGGGIAGAALALALARRgWQVTLYEADEAPAQGASGnRQGALYplLSKDDNALSRffraAFLFARRFYd 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  76 -LEHPPEGFSEHP---LLTPRGAMMVAGAEHMAELEAHWEVLRAMDTgasrlsgEQAREMVPALRPEqvlGAVYEPDAAD 151
Cdd:PRK01747  335 aLPAAGVAFDHDWcgvLQLAWDEKSAEKIAKMLALGLPAELARALDA-------EEAEELAGLPVPC---GGIFYPQGGW 404

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1538531800 152 MDVHAIHQGYLrgmRRAGGRLVCDAG--VTAIERVGERWRVEAGGSV-YEAPVVLNAAGAWVDTIARMAGVP 220
Cdd:PRK01747  405 LCPAELCRALL---ALAGQQLTIHFGheVARLEREDDGWQLDFAGGTlASAPVVVLANGHDAARFAQTAHLP 473
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 12-378 1.26e-06

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 49.83  E-value: 1.26e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  12 DFLVIGGGIAGASVAHWLAPHA-RVILLERESQPgyHSTGRS-------AALFMESYGTaqvralTMASRAF-LEHPPEG 82
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGkKTLLLEQFDLP--HSRGSShgqsriiRKAYPEDFYT------PMMLECYqLWAQLEK 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  83 FSEHPLLTPRGaMMVAGAEHMAELEAHWEVLRAMDTGASRLSGEQAREMVPALR-PEQVLGaVYEPDA----ADMDVHAi 157
Cdd:TIGR01377  74 EAGTKLHRQTG-LLLLGPKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRvPRNEVG-LLDPNGgvlyAEKALRA- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 158 hqgyLRGMRRAGGRLVCD-AGVTAIERVGERWRVEAGGSVYEAPVVLNAAGAWVDTIARMAGVpPLGIEPRRRSAFIFAP 236
Cdd:TIGR01377 151 ----LQELAEAHGATVRDgTKVVEIEPTELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGI-EIPLQPLRINVCYWRE 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 237 PEGQS---VAHWP--MVFGADEGWYIKPD---AGMLLGSPANADPVEPQDVQPEE----MDIAIAMHRIEEATTLSIRRP 304
Cdd:TIGR01377 226 KEPGSygvSQAFPcfLVLGLNPHIYGLPSfeyPGLMKVYYHHGQQIDPDERDCPFgadiEDVQILRKFVRDHLPGLNGEP 305

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1538531800 305 TRTWAGLRSFVPDGDLVGGFEPGMPGFFWVAAQGGYGIQTSAAMGEACAALARGLPLPERIASFGLTAEMLGPQ 378
Cdd:TIGR01377 306 KKGEVCMYTNTPDEHFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFALKKK 379
GlpA COG0578
Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate ...
 122-221 1.30e-06

Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Glycerol-3-phosphate dehydrogenase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 440343 [Multi-domain]  Cd Length: 501  Bit Score: 50.13  E-value: 1.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 122 RLSGEQAREMVPALRPEQVLGAVYEPDAAdMD----VHAIhqgyLRGMRRAGGRLVCDAGVTAIERVGER-WRVEA---- 192
Cdd:COG0578   104 RLSRAEALALAPLLRPDGLRGGFEYYDAQ-VDdarlVLEL----ARTAAERGAVVLNYTRVTGLLRDGGRvWGVTVrdrl 178

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1538531800 193 GGSVYE--APVVLNAAGAWVDTIARMAGVPP 221
Cdd:COG0578   179 TGEEFTvrARVVVNATGPWVDELRALDGPKA 209
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
15-48 8.02e-05

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 44.34  E-value: 8.02e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1538531800  15 VIGGGIAGASVAHWLAPHARVILLERESQPGYHS 48
Cdd:COG2907     8 VIGSGISGLTAAWLLSRRHDVTLFEANDRLGGHT 41
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 12-233 1.22e-04

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 43.77  E-value: 1.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  12 DFLVIGGGIAGASVAHWLAPH-ARVILLERESQPGYHStgrsaalfmesygtaQVRALTMASRAFLEHppegfsehpllt 90
Cdd:COG0654     5 DVLIVGGGPAGLALALALARAgIRVTVVERAPPPRPDG---------------RGIALSPRSLELLRR------------ 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  91 pRGAmmvagAEHMAELEAHWEVLRAMDTGASRlsgeqaremvpalrpeqVLGAVYEPDAADMDVHAIHQGYLRGM----- 165
Cdd:COG0654    58 -LGL-----WDRLLARGAPIRGIRVRDGSDGR-----------------VLARFDAAETGLPAGLVVPRADLERAlleaa 114

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1538531800 166 RRAGGRLVCDAGVTAIERVGERWRVE-AGGSVYEAPVVLNAAGAWvDTIARMAGVPPLGIEPRRRSAFI 233
Cdd:COG0654   115 RALGVELRFGTEVTGLEQDADGVTVTlADGRTLRADLVVGADGAR-SAVRRLLGIGFTGRDYPQRALWA 182
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 7-38 2.54e-04

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 42.79  E-value: 2.54e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1538531800   7 EPVVADFLVIGGGIAGASVAHWLAPHARVILL 38
Cdd:COG0029     1 ERLKTDVLVIGSGIAGLSAALKLAERGRVTLL 32
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 12-221 3.39e-04

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 42.51  E-value: 3.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  12 DFLVIGGGIAGASVAHWLA-PHARVILLERESQPG----------------YHStgrsaalFMESYGTAQ--VRALTMAS 72
Cdd:COG1232     3 RVAVIGGGIAGLTAAYRLAkAGHEVTVLEASDRVGglirtvevdgfridrgPHS-------FLTRDPEVLelLRELGLGD 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800  73 RafLEHPPEG----FSE---HPLltPRGAMMVAGAEHMAEleahWEVLRA-MDTGASRLSGEQA------------REMV 132
Cdd:COG1232    76 E--LVWPNTRksyiYYGgklHPL--PQGPLALLRSPLLSL----AGKLRAlLELLAPRRPPGEDeslaefvrrrfgREVY 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 133 PAL-RPeqVLGAVYEPDAADMDVHAI----------HQGYLRGMRRA-----------------------------GGRL 172
Cdd:COG1232   148 ERLvEP--LLEGVYAGDPDELSADWAfprlkrleleHGSLIKGALALrkgakagevfgylrgglgtlvealaealeAGEI 225

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1538531800 173 VCDAGVTAIERVGERWRVEAG-GSVYEAPVVLNAAGAWVdTIARMAGVPP 221
Cdd:COG1232   226 RLGTRVTAIEREGGGWRVTTSdGETIEADAVVSATPAPA-LARLLAPLPP 274
glpA PRK11101
anaerobic glycerol-3-phosphate dehydrogenase subunit A;
114-217 5.72e-04

anaerobic glycerol-3-phosphate dehydrogenase subunit A;


Pssm-ID: 236847 [Multi-domain]  Cd Length: 546  Bit Score: 41.93  E-value: 5.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1538531800 114 RAMDTGASRLSGEQAREMVPALRPEqVLGAVYEPD---------AADMdVHAIHQG-------YLRGMRRAGGRLVcdaG 177
Cdd:PRK11101  110 EEAGIEAEAIDPQQALILEPAVNPA-LIGAVKVPDgtvdpfrltAANM-LDAKEHGaqiltyhEVTGLIREGDTVC---G 184

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1538531800 178 VTAIE-RVGERWRVEAggsvyeaPVVLNAAGAWVDTIARMA 217
Cdd:PRK11101  185 VRVRDhLTGETQEIHA-------PVVVNAAGIWGQHIAEYA 218
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 13-45 7.86e-03

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 38.29  E-value: 7.86e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1538531800  13 FLVIGGGIAGASVAHWL---APHARVILLERESQPG 45
Cdd:PRK11883    3 VAIIGGGITGLSAAYRLhkkGPDADITLLEASDRLG 38
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 12-46 8.65e-03

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 37.68  E-value: 8.65e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1538531800  12 DFLVIGGGIAGASVAHWLA-PHARVILLERESQPGY 46
Cdd:TIGR02032   2 DVVVVGAGPAGASAAYRLAdKGLRVLLLEKKSFPRY 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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