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Conserved domains on  [gi|1541775983|gb|RTP15838|]
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iron ABC transporter permease [Enterobacter roggenkampii]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 40-343 1.52e-73

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 229.96  E-value: 1.52e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  40 GLTHGSLPIPASAIGRALFSPETlTAETRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAA 119
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGPDG-DPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 120 VLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALAR---DISRPRFILIGIGVSWAFAAAMGVFMTTADVRDVQTAMLWL 196
Cdd:COG0609    80 AVLAIVLGGGLSALGLPLAAFLGALLAALLVYLLARrggGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 197 AGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGL 276
Cdd:COG0609   160 MGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1541775983 277 IAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLPLQLPAGIVISLIGGPFFLLLLWQRR 343
Cdd:COG0609   240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 40-343 1.52e-73

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 229.96  E-value: 1.52e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  40 GLTHGSLPIPASAIGRALFSPETlTAETRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAA 119
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGPDG-DPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 120 VLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALAR---DISRPRFILIGIGVSWAFAAAMGVFMTTADVRDVQTAMLWL 196
Cdd:COG0609    80 AVLAIVLGGGLSALGLPLAAFLGALLAALLVYLLARrggGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 197 AGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGL 276
Cdd:COG0609   160 MGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1541775983 277 IAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLPLQLPAGIVISLIGGPFFLLLLWQRR 343
Cdd:COG0609   240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 34-341 2.53e-59

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 193.51  E-value: 2.53e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  34 LGLLGFGLTHGSLPIPASAIGRALFSPETLTAetRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGLADPGLIGVK 113
Cdd:pfam01032   3 LLLILLSLFIGAVKISPSDVFSALLGGDDSLA--ALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 114 EGCSAAVLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALAR---DISRPRFILIGIGVSWAFAAAMGVFMTTADVRDVQ 190
Cdd:pfam01032  81 SGAALGAVLAILLGGSLSLFALPLAAFIGALLAALLVYFLSRgrgGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 191 TAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTATCVSCVGS 270
Cdd:pfam01032 161 SILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGP 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1541775983 271 IGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLPLQLPAGIVISLIGGPFFLLLLWQ 341
Cdd:pfam01032 241 IGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-343 2.08e-46

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 166.94  E-value: 2.08e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983   1 MNRAGLRAIRVGRLSALVRPKALACLSLFALMALGLLGFGLTHGSLPIPASAIGRALFSpetltaetryVVMDIRLPRLL 80
Cdd:PRK10577  333 RSAQSAPAMSAGDRVAARRRRVLAWLLALGLLLLLALVVALSFGRDAHGWNWLSGQLLD----------ALLPLRLPRLL 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  81 MAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAAVLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALAR--DIS 158
Cdd:PRK10577  403 AALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALILLLARrgGFA 482

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 159 RPRFILIGIGVSWAFAAAMGVFMTTADVRdVQTAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQA 238
Cdd:PRK10577  483 PERLLLTGIALSALFTALIQLLLASGDPR-AAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDT 561

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 239 AAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLP 318
Cdd:PRK10577  562 ARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFP 641

                         330       340
                  ....*....|....*....|....*
gi 1541775983 319 LQLPAGIVISLIGGPFFLLLLWQRR 343
Cdd:PRK10577  642 YQIPAGLLAALIGAPYFLWLLRRSR 666
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 79-339 2.17e-33

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 124.21  E-value: 2.17e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  79 LLMAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAAVLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALARDIS 158
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 159 RPRFILIGIGVSW-AFAAAMGVFMTTADVRDVQTAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQ 237
Cdd:cd06550    81 LSPSKLILIGIVLsAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDED 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 238 AAAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLaFL 317
Cdd:cd06550   161 LAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRT-LL 239

                         250       260
                  ....*....|....*....|..
gi 1541775983 318 PLQLPAGIVISLIGGPFFLLLL 339
Cdd:cd06550   240 PSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 40-343 1.52e-73

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 229.96  E-value: 1.52e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  40 GLTHGSLPIPASAIGRALFSPETlTAETRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAA 119
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGPDG-DPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 120 VLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALAR---DISRPRFILIGIGVSWAFAAAMGVFMTTADVRDVQTAMLWL 196
Cdd:COG0609    80 AVLAIVLGGGLSALGLPLAAFLGALLAALLVYLLARrggGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 197 AGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGL 276
Cdd:COG0609   160 MGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1541775983 277 IAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLPLQLPAGIVISLIGGPFFLLLLWQRR 343
Cdd:COG0609   240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 1-345 2.11e-67

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 215.37  E-value: 2.11e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983   1 MNRAGLRAIRVGRLSALVRPKALACLSLFALMALGLLGFGLTHGSLPIPASAIGRALFSPETltAETRYVVMDIRLPRLL 80
Cdd:COG4779     1 MSATSTRVLRVGRVSLRLRRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGD--PGASFVVLELRLPRAL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  81 MAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAAVLLLIFQFPAlSLAWRPLVGMAGGLLTALLVIALA--RDIS 158
Cdd:COG4779    79 AALLVGAALGLSGAIFQSLTRNPLASPDIIGITAGASAGAVAAIVVLGG-SGLAVALGALAGGLATALLVYLLAwrGGVS 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 159 RPRFILIGIGVSWAFAAAMGVFMTTADVRDVQTAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQA 238
Cdd:COG4779   158 GYRLILVGIGVSAMLTAVNSYLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDT 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 239 AAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGLIAPHMARLLLRGGQTALLtGSAVLGALLVLLADNVGRLAFLP 318
Cdd:COG4779   238 AAALGVRVERTRLLLLLVAVALAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLL-PSALVGALLLLAADLVAQHLLAP 316

                         330       340
                  ....*....|....*....|....*..
gi 1541775983 319 LQLPAGIVISLIGGPFFLLLLWQRRDR 345
Cdd:COG4779   317 VQLPVGVVTGALGGPYLLWLLIRENRR 343
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 34-341 2.53e-59

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 193.51  E-value: 2.53e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  34 LGLLGFGLTHGSLPIPASAIGRALFSPETLTAetRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGLADPGLIGVK 113
Cdd:pfam01032   3 LLLILLSLFIGAVKISPSDVFSALLGGDDSLA--ALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 114 EGCSAAVLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALAR---DISRPRFILIGIGVSWAFAAAMGVFMTTADVRDVQ 190
Cdd:pfam01032  81 SGAALGAVLAILLGGSLSLFALPLAAFIGALLAALLVYFLSRgrgGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQ 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 191 TAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTATCVSCVGS 270
Cdd:pfam01032 161 SILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGP 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1541775983 271 IGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLPLQLPAGIVISLIGGPFFLLLLWQ 341
Cdd:pfam01032 241 IGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
1-343 2.08e-46

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 166.94  E-value: 2.08e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983   1 MNRAGLRAIRVGRLSALVRPKALACLSLFALMALGLLGFGLTHGSLPIPASAIGRALFSpetltaetryVVMDIRLPRLL 80
Cdd:PRK10577  333 RSAQSAPAMSAGDRVAARRRRVLAWLLALGLLLLLALVVALSFGRDAHGWNWLSGQLLD----------ALLPLRLPRLL 402

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  81 MAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAAVLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALAR--DIS 158
Cdd:PRK10577  403 AALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALILLLARrgGFA 482

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 159 RPRFILIGIGVSWAFAAAMGVFMTTADVRdVQTAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQA 238
Cdd:PRK10577  483 PERLLLTGIALSALFTALIQLLLASGDPR-AAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDT 561

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 239 AAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLP 318
Cdd:PRK10577  562 ARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFP 641

                         330       340
                  ....*....|....*....|....*
gi 1541775983 319 LQLPAGIVISLIGGPFFLLLLWQRR 343
Cdd:PRK10577  642 YQIPAGLLAALIGAPYFLWLLRRSR 666
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
31-343 3.39e-43

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 151.74  E-value: 3.39e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  31 LMALGLLGFGLTHGSLPIPASAIGRALFSPEtltaETRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGLADPGLI 110
Cdd:PRK09777   11 LALAGCALLSLRMGVIPLPWRALLTDWQAGD----EHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDIL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 111 GVKEGCSAAVLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALARDISRPRFILIGIGVSWAFAAAMGVFMTTADVrDVQ 190
Cdd:PRK09777   87 GVNHAASLASVGALLLFPSLPVMWLPLLAFIGGMAGLILLKMLAGTHQPMKLALTGVALSALWASLTDYLMLSRPQ-DIN 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 191 TAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTATCVSCVGS 270
Cdd:PRK09777  166 NALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGP 245

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1541775983 271 IGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLPLQLPAGIVISLIGGPFFLLLLWQRR 343
Cdd:PRK09777  246 ISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLLVRMR 318
btuC PRK09535
cobalamin ABC transporter permease BtuC;
34-342 2.94e-37

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 137.19  E-value: 2.94e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  34 LGLLGFGLTHGSLPIPASAIGRALFSPET--LTAETRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGLADPGLIG 111
Cdd:PRK09535   52 VAVTTHGVPVLSVGLSLPAPDLEYASPFSfaVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIG 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 112 VKEGCSAAVLLLIFqFPALSLAWRPLVGMAGGLLTALLVIALARDISR-PRFILIGIGVS-WAFAAAMGVFMTTADVRDV 189
Cdd:PRK09535  132 VSSGAAVGAVAAIV-LPLAVPFGLQAAAFAGALVAAFGVYAIATENGRtPVATLLLAGVAvQTFLGAVISYLLLHSGESL 210

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 190 QTAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTATCVSCVG 269
Cdd:PRK09535  211 RRAVYWLMGHLHGSTWSDVEVALPVVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAG 290

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1541775983 270 SIGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAflPLQLPAGIVISLIGGPFFLLLLWQR 342
Cdd:PRK09535  291 VIGFVGLIVPHVMRLLVGPDHRILLPTSALAGASFLVATDTVARSG--PAEVPVGIVTAALGAPFFLYLLRTR 361
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
19-345 1.07e-35

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 136.89  E-value: 1.07e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  19 RPKALACLSLFALMALGLLGFGLTHGSLPIPASAIGRALFSPETLTAEtRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQT 98
Cdd:PRK10577    7 RRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLE-QLLLHYSRLPRLAIALLVGAALGLAGALLQQ 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  99 ITRNGLADPGLIGVKEGCSAAVLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALA--RDISRPRFILIGIGVSWAFAAA 176
Cdd:PRK10577   86 VLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASQLAAFAGGLLAAALVFALAggKRLSPLRLVLAGMVVSLYLGAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 177 MGVFMTTADVRdVQTAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLA 256
Cdd:PRK10577  166 TTLLLLFNEQY-LQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALAL 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 257 PVVLTATCVSCVGSIGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRL--AFLPLQLPAGIVISLIGGPF 334
Cdd:PRK10577  245 AVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLlaGVGGELLPTGAVTALIGAPL 324

                         330
                  ....*....|.
gi 1541775983 335 FLLLLWQRRDR 345
Cdd:PRK10577  325 LLWLLPRLRSA 335
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 25-344 1.59e-35

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 131.51  E-value: 1.59e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  25 CLSLFALMALGLLGFGLTHGSLPIPASAIgralfspetLTAETRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGL 104
Cdd:COG4139    14 WLLLLLLLLLLLFVLSLCAGEVWIPPTQW---------LSEAWQLFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 105 ADPGLIGVKEGCSAAVLLLIFQFPALSLAWRPLVG-MAGGLLTALLVIALARDI-SRPRFILIGIGVSWAFAAAMGVFMT 182
Cdd:COG4139    85 AEPGLLGISNGAGVGLVLVVLLGGGLLPPWLLSLAaIAGALLVTLLLLAFARRRlSNARLLLIGVALGIICSAIMTWAVY 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 183 TADVRDVQTAMLWLAGSLHAANWTLvGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTA 262
Cdd:COG4139   165 FSSSLDLRQLMYWMMGSFGGVDWRQ-LWLLLALLPVLLWLCLQGKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVG 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 263 TCVSCVGSIGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLPLQLPAGIVISLIGGPFFLLLLWQR 342
Cdd:COG4139   244 VSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLADIIARLALSSAELPIGVVTATLGAPVFIWLLLRR 323


                  ..
gi 1541775983 343 RD 344
Cdd:COG4139   324 RK 325
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 79-339 2.17e-33

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 124.21  E-value: 2.17e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  79 LLMAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAAVLLLIFQFPALSLAWRPLVGMAGGLLTALLVIALARDIS 158
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRGG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 159 RPRFILIGIGVSW-AFAAAMGVFMTTADVRDVQTAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQ 237
Cdd:cd06550    81 LSPSKLILIGIVLsAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDED 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 238 AAAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLaFL 317
Cdd:cd06550   161 LAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRT-LL 239

                         250       260
                  ....*....|....*....|..
gi 1541775983 318 PLQLPAGIVISLIGGPFFLLLL 339
Cdd:cd06550   240 PSELPVGPVTALLGAPYFLYLL 261
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
18-341 9.02e-32

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 121.74  E-value: 9.02e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  18 VRPKALACLSLFALMALGLLGFGLTHGSLPIPASAIGRALF--SPETLTAetryVVMDIRLPRLLMAVLCGAMLGMAGAA 95
Cdd:PRK10440    4 VSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMgdAPRSMTM----VVTEWRLPRVLMALLIGAALGVSGAI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  96 MQTITRNGLADPGLIGVKEGCSAAVLLLIFQFPAlSLAWRPLVGMAGGLLTALLVIALA--RDISRPRFILIGIGVSWAF 173
Cdd:PRK10440   80 FQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQ-DLTAIALAAMAGGIVTSLLVWLLAwrNGIDTFRLIIIGIGVRAML 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 174 AAAMGVFMTTADVRDVQTAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLR 253
Cdd:PRK10440  159 VAFNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 254 VLAPVVLTATCVSCVGSIGFVGLIAPHMARLLLRGGQTALLTgSAVLGALLVLLADNVGRLAFLPLQLPAGIVISLIGGP 333
Cdd:PRK10440  239 MLVAVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQ-AALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGI 317


                  ....*...
gi 1541775983 334 FFLLLLWQ 341
Cdd:PRK10440  318 YLIVLLIQ 325
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
45-343 1.25e-31

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 120.96  E-value: 1.25e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  45 SLPIPASAIGRALFsPETLTAETRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAAVLLLI 124
Cdd:PRK11228   22 AIPISAADALNALL-PGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTS 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 125 FQFPALSLAWR-PLVGMAGGLLTALLVIALARDIS----RPRFILIGIGVSWAFAAAMGVFMTTADVRdVQTAMLWLAGS 199
Cdd:PRK11228  101 ALSPTPFAGYSlAFIAACGGGLSWLLVMTAGGGWRhthdRNRLILAGIALSALCMALTRITLLLAEDH-AYGIFYWLAGG 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 200 LHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGLIAP 279
Cdd:PRK11228  180 VSHARWQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVP 259

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1541775983 280 HMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLAFLPLQLPAGIVISLIGGPFFLLLLWQRR 343
Cdd:PRK11228  260 HLARFWIGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLARRRG 323
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 63-345 5.09e-31

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 119.68  E-value: 5.09e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  63 LTAETRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQTITRNGLADPGLIGVKEGCSAAVLLLIFQFPALSLAWR-PLVGMA 141
Cdd:PRK03784   46 LSPRGELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWAlSLCAIA 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 142 GGLLTALLVIALAR--DISRPRFILIGIGVSWAFAAAMGVFMTTADVRDVQTAMLWLAGSLHAANWTLvGLAALWAAPAF 219
Cdd:PRK03784  126 GALLITLILLRFARrhRLSTSRLLLAGVALGIICSALMTWAVYFSTSLDLRQLMYWMMGGFGGVDWRQ-SWLMLALLPVL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 220 ALLLFTARAADVALLGNQAAAGLGVRTTRLALLRVLAPVVLTATCVSCVGSIGFVGLIAPHMARLLLRGGQTALLTGSAV 299
Cdd:PRK03784  205 IWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCAL 284

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1541775983 300 LGALLVLLADNVGRLAFLPLQLPAGIVISLIGGPFFLLLLWQRRDR 345
Cdd:PRK03784  285 AGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHRA 330
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
18-343 4.23e-27

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 109.03  E-value: 4.23e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  18 VRPKALACLSLFALMALGLlgfGLTHGSLPIPASAIGRALFSpeTLTAETRYVVMDIRLPRLLMAVLCGAMLGMAGAAMQ 97
Cdd:PRK10441    8 TRAIAVPGLLLLLIIATAL---SLLIGAKSLPASVVLEALSG--TCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983  98 TITRNGLADPGLIGVKEGCSAAVLLLIFQFPALSLAWRPLVGMAGGLLTALLVI----ALARDISRPRFILIGIGVSWAF 173
Cdd:PRK10441   83 TLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAftgsQGGGQLSPVRLTLAGVALAAVL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 174 -AAAMGVFMTTADVRDvqTAMLWLAGSLHAANWTLVGLAALWAAPAFALLLFTARAADVALLGNQAAAGLGVRTTRLALL 252
Cdd:PRK10441  163 eGLTSGIALLNPDVYD--QLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLI 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1541775983 253 RVLAPVVLTATCVSCVGSIGFVGLIAPHMARLLLRGGQTALLTGSAVLGALLVLLADNVGRLaFLPLQLPAGIVISLIGG 332
Cdd:PRK10441  241 GLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRL-LVPGELRVSVVSAFIGA 319

                         330
                  ....*....|.
gi 1541775983 333 PFFLLLLWQRR 343
Cdd:PRK10441  320 PVLIFLVRRKT 330
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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