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Conserved domains on  [gi|1546372268|gb|RUR40019|]
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ketose 1,6-bisphosphate aldolase [Citrobacter portucalensis]

Protein Classification

triose-phosphate isomerase; tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like( domain architecture ID 10792823)

triose-phosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate| tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like (DUS1L) catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
1-285 0e+00

ketose 1,6-bisphosphate aldolase;


:

Pssm-ID: 180701  Cd Length: 286  Bit Score: 572.47  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLN 80
Cdd:PRK06801    1 MALISLANGLAHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLESLVEAVKFEAARHDIPVVLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  81 LDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGHADESLFTDPMM 160
Cdd:PRK06801   81 LDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEADSAKFTDPQL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 161 ARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAA 240
Cdd:PRK06801  161 ARDFVDRTGIDALAVAIGNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDADFRRAIELGIHKINFYTGMSQAA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1546372268 241 LSAVETRMANRQPLYDEFAELLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:PRK06801  241 LAAVEQRMTHRHAIYDEFAELLLGIEEAISDTVAQQMRIFGSAGQ 285
 
Name Accession Description Interval E-value
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
1-285 0e+00

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 572.47  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLN 80
Cdd:PRK06801    1 MALISLANGLAHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLESLVEAVKFEAARHDIPVVLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  81 LDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGHADESLFTDPMM 160
Cdd:PRK06801   81 LDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEADSAKFTDPQL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 161 ARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAA 240
Cdd:PRK06801  161 ARDFVDRTGIDALAVAIGNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDADFRRAIELGIHKINFYTGMSQAA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1546372268 241 LSAVETRMANRQPLYDEFAELLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:PRK06801  241 LAAVEQRMTHRHAIYDEFAELLLGIEEAISDTVAQQMRIFGSAGQ 285
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 2-285 1.88e-131

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 374.04  E-value: 1.88e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   2 PLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLNL 81
Cdd:COG0191     1 MLVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLEYLAAMVRAAAEEASVPVALHL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  82 DHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGaLYGHADESLFTDPMMA 161
Cdd:COG0191    81 DHGASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDG-VDVDDAEALYTDPEEA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 162 RDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAAL 241
Cdd:COG0191   160 AEFVEETGVDALAVAIGTVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFT 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1546372268 242 SAVETRMANRQPLYDeFAELLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:COG0191   240 AAVREYLAENPDKYD-PRKYLKPAREAMKEVVKEKIRLFGSAGK 282
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 8-284 1.22e-128

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 366.47  E-value: 1.22e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   8 DGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLNLDHGLHF 87
Cdd:cd00947     3 ELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAGLELLVAMVKAAAERASVPVALHLDHGSSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  88 ESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGAlygHADESLFTDPMMARDFVDR 167
Cdd:cd00947    83 ELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGV---VGDEGLLTDPEEAEEFVEE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 168 TGIDALAVAIGNAHGKYKG-EPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAALSAVET 246
Cdd:cd00947   160 TGVDALAVAIGTSHGAYKGgEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALRE 239

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1546372268 247 RMANRQPLYDeFAELLLGIEEAITDTVSEQMRIFGSAG 284
Cdd:cd00947   240 YLAENPKEFD-PRKYLAPAIEAVKEVVKHKMELFGSAG 276
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
4-285 1.75e-122

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 350.94  E-value: 1.75e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   4 ISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKY--ISLDSLVEAVKFEAARHDIPVVLNL 81
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKyaGGAEALAALVRAAAEAAGVPVALHL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  82 DHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGAlygHADESLFTDPMMA 161
Cdd:pfam01116  81 DHGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGV---VVDEKLYTDPEEA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 162 RDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAAL 241
Cdd:pfam01116 158 AEFVEATGVDALAVAIGNVHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFT 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1546372268 242 SAVETRMANRQPLydefaELLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:pfam01116 238 AAVREYPPNKDPR-----KYLRPAEEAMKEVVKEKIRLFGSAGK 276
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 1-285 3.28e-92

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 274.58  E-value: 3.28e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYIS-LDSLVEAVK--FEAARHDIPV 77
Cdd:TIGR00167   1 MMLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAgLGAISAMVKamSEAYPYGVPV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  78 VLNLDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGAlyGHADES-LFT 156
Cdd:TIGR00167  81 ALHLDHGASEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVEAELGTLGGEEDGV--SVADESaLYT 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 157 DPMMARDFVDRTGIDALAVAIGNAHGKYKGEP-LLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTG 235
Cdd:TIGR00167 159 DPEEAKEFVKLTGVDSLAAAIGNVHGVYKGEPkGLDFERLEEIQKYVNLPLVLHGGSGIPDEEIKKAISLGVVKVNIDTE 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1546372268 236 MSQAALSAVETRMANRQPLYDEFAELLLGiEEAITDTVSEQMRIFGSAGR 285
Cdd:TIGR00167 239 LQIAFAAAVRNYYAENKDYYDPRVWLRPG-EKAMKEVVLEKIKLFGSANK 287
 
Name Accession Description Interval E-value
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
1-285 0e+00

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 572.47  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLN 80
Cdd:PRK06801    1 MALISLANGLAHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLESLVEAVKFEAARHDIPVVLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  81 LDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGHADESLFTDPMM 160
Cdd:PRK06801   81 LDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEADSAKFTDPQL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 161 ARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAA 240
Cdd:PRK06801  161 ARDFVDRTGIDALAVAIGNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDADFRRAIELGIHKINFYTGMSQAA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1546372268 241 LSAVETRMANRQPLYDEFAELLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:PRK06801  241 LAAVEQRMTHRHAIYDEFAELLLGIEEAISDTVAQQMRIFGSAGQ 285
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 2-285 1.88e-131

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 374.04  E-value: 1.88e-131
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   2 PLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLNL 81
Cdd:COG0191     1 MLVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLEYLAAMVRAAAEEASVPVALHL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  82 DHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGaLYGHADESLFTDPMMA 161
Cdd:COG0191    81 DHGASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDG-VDVDDAEALYTDPEEA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 162 RDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAAL 241
Cdd:COG0191   160 AEFVEETGVDALAVAIGTVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFT 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1546372268 242 SAVETRMANRQPLYDeFAELLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:COG0191   240 AAVREYLAENPDKYD-PRKYLKPAREAMKEVVKEKIRLFGSAGK 282
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 8-284 1.22e-128

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 366.47  E-value: 1.22e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   8 DGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLNLDHGLHF 87
Cdd:cd00947     3 ELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAGLELLVAMVKAAAERASVPVALHLDHGSSF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  88 ESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGAlygHADESLFTDPMMARDFVDR 167
Cdd:cd00947    83 ELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGV---VGDEGLLTDPEEAEEFVEE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 168 TGIDALAVAIGNAHGKYKG-EPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAALSAVET 246
Cdd:cd00947   160 TGVDALAVAIGTSHGAYKGgEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALRE 239

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1546372268 247 RMANRQPLYDeFAELLLGIEEAITDTVSEQMRIFGSAG 284
Cdd:cd00947   240 YLAENPKEFD-PRKYLAPAIEAVKEVVKHKMELFGSAG 276
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
4-285 1.75e-122

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 350.94  E-value: 1.75e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   4 ISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKY--ISLDSLVEAVKFEAARHDIPVVLNL 81
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKyaGGAEALAALVRAAAEAAGVPVALHL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  82 DHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGAlygHADESLFTDPMMA 161
Cdd:pfam01116  81 DHGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGV---VVDEKLYTDPEEA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 162 RDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAAL 241
Cdd:pfam01116 158 AEFVEATGVDALAVAIGNVHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFT 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1546372268 242 SAVETRMANRQPLydefaELLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:pfam01116 238 AAVREYPPNKDPR-----KYLRPAEEAMKEVVKEKIRLFGSAGK 276
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
1-286 1.02e-99

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 293.56  E-value: 1.02e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLN 80
Cdd:PRK12857    1 MMLVTVAELLKKAEKGGYAVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKYAGIEYISAMVRTAAEKASVPVALH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  81 LDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGAlygHADE--SLFTDP 158
Cdd:PRK12857   81 LDHGTDFEQVMKCIRNGFTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAELGKIGGTEDDI---TVDEreAAMTDP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 159 MMARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQ 238
Cdd:PRK12857  158 EEARRFVEETGVDALAIAIGTAHGPYKGEPKLDFDRLAKIKELVNIPIVLHGSSGVPDEAIRKAISLGVRKVNIDTNIRE 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1546372268 239 AALSAVETRMANRQPLYDEfAELLLGIEEAITDTVSEQMRIFGSAGRV 286
Cdd:PRK12857  238 AFVARLREVLEKNPDEIDP-RKILGPAREAAKEVIREKIRLFGSAGKA 284
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 1-285 3.28e-92

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 274.58  E-value: 3.28e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYIS-LDSLVEAVK--FEAARHDIPV 77
Cdd:TIGR00167   1 MMLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAgLGAISAMVKamSEAYPYGVPV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  78 VLNLDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGAlyGHADES-LFT 156
Cdd:TIGR00167  81 ALHLDHGASEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVEAELGTLGGEEDGV--SVADESaLYT 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 157 DPMMARDFVDRTGIDALAVAIGNAHGKYKGEP-LLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTG 235
Cdd:TIGR00167 159 DPEEAKEFVKLTGVDSLAAAIGNVHGVYKGEPkGLDFERLEEIQKYVNLPLVLHGGSGIPDEEIKKAISLGVVKVNIDTE 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1546372268 236 MSQAALSAVETRMANRQPLYDEFAELLLGiEEAITDTVSEQMRIFGSAGR 285
Cdd:TIGR00167 239 LQIAFAAAVRNYYAENKDYYDPRVWLRPG-EKAMKEVVLEKIKLFGSANK 287
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 3-285 3.58e-92

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 274.24  E-value: 3.58e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   3 LISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYIS-LDSLVEAVKFEAARH-DIPVVLN 80
Cdd:TIGR01859   1 LVNGKEILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYMGgYKMAVAMVKTLIERMsIVPVALH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  81 LDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALyghADESLFTDPMM 160
Cdd:TIGR01859  81 LDHGSSYESCIKAIKAGFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGIEDGVD---EKEAELADPDE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 161 ARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAA 240
Cdd:TIGR01859 158 AEQFVKETGVDYLAAAIGTSHGKYKGEPGLDFERLKEIKELTNIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAF 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1546372268 241 LSAVETRMANRQPLYDEFAELLLGIeEAITDTVSEQMRIFGSAGR 285
Cdd:TIGR01859 238 TAAIRKVLTEKKDEYDPRKILGPAR-EAIKETVKEKMRLFGSAGK 281
PRK06806 PRK06806
class II aldolase;
1-285 1.65e-85

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 257.38  E-value: 1.65e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDsLVEAVKFEAARH-DIPVVL 79
Cdd:PRK06806    1 MPLVQMKELLKKANQENYGVGAFSVANMEMVMGAIKAAEELNSPIILQIAEVRLNHSPLH-LIGPLMVAAAKQaKVPVAV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  80 NLDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGAlygHADESLFTDPM 159
Cdd:PRK06806   80 HFDHGMTFEKIKEALEIGFTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGS---EDIEMLLTSTT 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 160 MARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQA 239
Cdd:PRK06806  157 EAKRFAEETDVDALAVAIGNAHGMYNGDPNLRFDRLQEINDVVHIPLVLHGGSGISPEDFKKCIQHGIRKINVATATFNS 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1546372268 240 ALSAVEtRMANRQPLYDEFAeLLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:PRK06806  237 VITAVN-NLVLNTPYSDYFT-YHQDVIKAAYENVKKHMQIFGSENK 280
PRK08185 PRK08185
hypothetical protein; Provisional
 8-286 2.81e-85

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 256.96  E-value: 2.81e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   8 DGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISlDSLVEAVKFEAARHDIPVVLNLDHGLHF 87
Cdd:PRK08185    3 ELLKVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNELDFLG-DNFFAYVRERAKRSPVPFVIHLDHGATI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  88 ESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVgGDEGGALYGHADESLFTDPMMARDFVDR 167
Cdd:PRK08185   82 EDVMRAIRCGFTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELGTI-GNTGTSIEGGVSEIIYTDPEQAEDFVSR 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 168 TGIDALAVAIGNAHGKYK--GEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAALSAVE 245
Cdd:PRK08185  161 TGVDTLAVAIGTAHGIYPkdKKPELQMDLLKEINERVDIPLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAFFKKVR 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1546372268 246 TRMANRQPLYDEFAeLLLGIEEAITDTVSEQMRIFGSAGRV 286
Cdd:PRK08185  241 EILSDNPSLYEPNQ-IYPSAIEAAKEVVRHKMDLFNSTGKA 280
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 1-286 5.88e-85

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 256.21  E-value: 5.88e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLN 80
Cdd:PRK09195    1 MYLVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAAELHSPVIIAGTPGTFSYAGTEYLLAIVSAAAKQYHHPLALH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  81 LDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGHADeSLFTDPMM 160
Cdd:PRK09195   81 LDHHEKFDDIAQKVRSGVRSVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLGGQEDDLQVDEAD-ALYTDPAQ 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 161 ARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAA 240
Cdd:PRK09195  160 AREFVEATGIDSLAVAIGTAHGMYKGEPKLDFDRLENIRQWVNIPLVLHGASGLPTKDIQQTIKLGICKVNVATELKIAF 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1546372268 241 LSAVETRMaNRQPLYDEFAELLLGIEEAITDTVSEQMRIFGSAGRV 286
Cdd:PRK09195  240 SQALKNYL-TEHPEANDPRHYLQPAKSAMKDVVSKVIADCGCEGKA 284
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
1-286 9.79e-83

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 250.38  E-value: 9.79e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLN 80
Cdd:PRK12737    1 MYIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSYAGTDYIVAIAEVAARKYNIPLALH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  81 LDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGHADeSLFTDPMM 160
Cdd:PRK12737   81 LDHHEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVDEKD-AMYTNPDA 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 161 ARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAA 240
Cdd:PRK12737  160 AAEFVERTGIDSLAVAIGTAHGLYKGEPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKIAF 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1546372268 241 LSAVETRMANRQPLYDEFAELLLGiEEAITDTVSEQMRIFGSAGRV 286
Cdd:PRK12737  240 SDAVKKYFYENPKANDPRKYMTPG-KAAMKEVVREKIKVCGSEGKL 284
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 1-285 3.34e-77

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 236.42  E-value: 3.34e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYIS-LDSLVEAVkfEAARHD----I 75
Cdd:PRK08610    1 MPLVSMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSgFYTVVKMV--EGLMHDlnitI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  76 PVVLNLDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALyghADESLF 155
Cdd:PRK08610   79 PVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVV---ADGIIY 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 156 TDPMMARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTG 235
Cdd:PRK08610  156 ADPKECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTE 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 1546372268 236 MSQAALSAVETRMANRQPLYDEfAELLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:PRK08610  236 NQIASAKAVRDVLNNDKEVYDP-RKYLGPAREAIKETVKGKIKEFGTSNR 284
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 1-285 8.12e-74

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 227.63  E-value: 8.12e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYIS-LDSLVEAVK--FEAARHDIPV 77
Cdd:PRK07709    1 MPLVSMKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHMTgFKTVVAMVKalIEEMNITVPV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  78 VLNLDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALyghADESLFTD 157
Cdd:PRK07709   81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVI---AEGVIYAD 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 158 PMMARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMS 237
Cdd:PRK07709  158 PAECKHLVEATGIDCLAPALGSVHGPYKGEPNLGFAEMEQVRDFTGVPLVLHGGTGIPTADIEKAISLGTSKINVNTENQ 237

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1546372268 238 QAALSAVETRMANRQPLYDEFAELLLGiEEAITDTVSEQMRIFGSAGR 285
Cdd:PRK07709  238 IEFTKAVREVLNKDQEVYDPRKFIGPG-RDAIKATVIGKIREFGSNGK 284
gatY PRK07998
class II aldolase;
1-282 9.25e-70

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 217.32  E-value: 9.25e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLN 80
Cdd:PRK07998    1 MPLVNGRILLDRIQEKHVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  81 LDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALyghADESLFTDPMM 160
Cdd:PRK07998   81 LDHGKTFEDVKQAVRAGFTSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAILGKEDDHV---SEADCKTEPEK 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 161 ARDFVDRTGIDALAVAIGNAHGKYKgEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAA 240
Cdd:PRK07998  158 VKDFVERTGCDMLAVSIGNVHGLED-IPRIDIPLLKRIAEVSPVPLVIHGGSGIPPEILRSFVNYKVAKVNIASDLRKAF 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1546372268 241 LSAVETRMANRQPLYDeFAELLLGIEEAITDTVSEQMRIFGS 282
Cdd:PRK07998  237 ITTVGKAYVNNHNEAN-LARVMAKAKQAVEEDVYSKIKMMNS 277
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
3-286 5.53e-69

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 215.99  E-value: 5.53e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   3 LISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARH-DIPVVLNL 81
Cdd:PRK05835    2 LVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYpHIPVALHL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  82 DHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGHADeSLFTDPMMA 161
Cdd:PRK05835   82 DHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKD-AVLVNPKEA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 162 RDFVDRTGIDALAVAIGNAHG--KYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDD----------DFKRAIGL---- 225
Cdd:PRK05835  161 EQFVKESQVDYLAPAIGTSHGafKFKGEPKLDFERLQEVKRLTNIPLVLHGASAIPDDvrksyldaggDLKGSKGVpfef 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1546372268 226 -------GIHKINFYTGMSQAALSAVEtRMANRQPLYDEFAELLLGIEEAITDTVSEQMRIFGSAGRV 286
Cdd:PRK05835  241 lqesvkgGINKVNTDTDLRIAFIAEVR-KVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI 307
tag_bisphos_ald TIGR01858
class II aldolase, tagatose bisphosphate family; This model describes tagatose-1, ...
 3-285 2.12e-68

class II aldolase, tagatose bisphosphate family; This model describes tagatose-1,6-bisphosphate aldolases, and perhaps other closely related class II aldolases. This tetrameric, Zn2+-dependent enzyme is related to the class II fructose bisphosphate aldolase; fructose 1,6-bisphosphate and tagatose 1,6 bisphosphate differ only in chirality at C4.


Pssm-ID: 130917  Cd Length: 282  Bit Score: 213.57  E-value: 2.12e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   3 LISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLNLD 82
Cdd:TIGR01858   1 IVSTKYMLQDAQAGGYAVPAFNIHNLETIQAVVETAAEMRSPVILAGTPGTFKHAGTEYIVALCSAASTTYNMPLALHLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  83 HGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGaLYGHADESLFTDPMMAR 162
Cdd:TIGR01858  81 HHESLDDIRQKVHAGVRSAMIDGSHFPFAQNVKLVKEVVDFCHRQDCSVEAELGRLGGVEDD-LSVDEEDALYTDPQEAK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 163 DFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAALS 242
Cdd:TIGR01858 160 EFVEATGVDSLAVAIGTAHGLYKKTPKLDFDRLAEIREVVDVPLVLHGASDVPDEDVRRTIELGICKVNVATELKIAFSG 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1546372268 243 AVETRMANRQPLYDEFAELLLGiEEAITDTVSEQMRIFGSAGR 285
Cdd:TIGR01858 240 AVKAYFAENPQANDPRYYMRPG-KDAMKKVVRNKINVCGSAGR 281
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
1-286 4.72e-61

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 195.25  E-value: 4.72e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLDSLVEAVKFEAARHDIPVVLN 80
Cdd:PRK12738    1 MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  81 LDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGaLYGHADESLFTDPMM 160
Cdd:PRK12738   81 LDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDD-MSVDAESAFLTDPQE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 161 ARDFVDRTGIDALAVAIGNAHGKYKGEPLLDFPRLDAIRQQAAIPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAA 240
Cdd:PRK12738  160 AKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAF 239

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1546372268 241 LSAVETRMANRQPLYDEFAELLLGIeEAITDTVSEQMRIFGSAGRV 286
Cdd:PRK12738  240 AGAVKAWFAENPQGNDPRYYMRVGM-DAMKEVVRNKINVCGSANRI 284
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
1-284 1.42e-54

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 180.15  E-value: 1.42e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKY---ISLDSLVEAVkFEAARHdIPV 77
Cdd:PRK09196    1 MALISLRQLLDHAAEHGYGVPAFNVNNLEQVQAIMEAADETDSPVILQASAGARKYagePFLRHLILAA-VEEYPH-IPV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  78 VLNLDHGLHFESVVRALRLGFSSVMFDGSTLE-------YEENIRQTREVVKMCHAVGVSVEAELGAVGGDE---GGALY 147
Cdd:PRK09196   79 VMHQDHGNSPATCQRAIQLGFTSVMMDGSLKAdgktpasYEYNVDVTRKVVEMAHACGVSVEGELGCLGSLEtgmGGEED 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 148 GHADE------SLFTDPMMARDFVDRTGIDALAVAIGNAHGKYK------GEpLLDFPRLDAIrqQAAIP---LVLHGGS 212
Cdd:PRK09196  159 GHGAEgklshdQLLTDPEEAADFVKKTQVDALAIAIGTSHGAYKftrkptGD-VLAIDRIKEI--HARLPnthLVMHGSS 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 213 ---------------------GISDDDFKRAIGLGIHKINFYTGMSQAALSAVETRMANRQPLYDEfAELLLGIEEAITD 271
Cdd:PRK09196  236 svpqelldiineyggdmpetyGVPVEEIQEGIKHGVRKVNIDTDLRLAMTGAIRRFLAENPSEFDP-RKYLKPAMEAMKK 314

                         330
                  ....*....|...
gi 1546372268 272 TVSEQMRIFGSAG 284
Cdd:PRK09196  315 ICKARYEAFGTAG 327
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
1-285 3.72e-52

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 173.81  E-value: 3.72e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKY---ISLDSLVEAVkfeAARH-DIP 76
Cdd:PRK13399    1 MALITLRQLLDHAAENGYGVPAFNVNNMEQILAIMEAAEATDSPVILQASRGARKYagdAMLRHMVLAA---AEMYpDIP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  77 VVLNLDHGLHFESVVRALRLGFSSVMFDGSTLE-------YEENIRQTREVVKMCHAVGVSVEAELGAVGGDE---GGAL 146
Cdd:PRK13399   78 ICLHQDHGNSPATCQSAIRSGFTSVMMDGSLLAdgktpasYDYNVDVTRRVTEMAHAVGVSVEGELGCLGSLEtgeAGEE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 147 YGHADES------LFTDPMMARDFVDRTGIDALAVAIGNAHGKYK--GEPLLDFPRLDAIRQ-QAAIP---LVLHGGS-- 212
Cdd:PRK13399  158 DGVGAEGklshdqMLTDPDQAVDFVQRTGVDALAIAIGTSHGAYKftRKPDGDILAIDRIEEiHARLPnthLVMHGSSsv 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 213 -------------------GISDDDFKRAIGLGIHKINFYTGMSQAALSAVETRMANRQPLYDEFAELLLGIEEAiTDTV 273
Cdd:PRK13399  238 pqelqeiinayggkmketyGVPVEEIQRGIKHGVRKVNIDTDIRLAMTGAIRKVLAEHPSEFDPRKALKPAMKAM-TALC 316

                         330
                  ....*....|..
gi 1546372268 274 SEQMRIFGSAGR 285
Cdd:PRK13399  317 KQRFEAFGTAGQ 328
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 1-285 9.37e-50

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 166.21  E-value: 9.37e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYIS--------LDSLVEAVKFEaar 72
Cdd:PRK07315    1 MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGgykvcknlIENLVESMGIT--- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  73 hdIPVVLNLDHGlHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGaLYGHADE 152
Cdd:PRK07315   78 --VPVAIHLDHG-HYEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDG-IIGKGEL 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 153 SLFTDpmmARDFVDrTGIDALAVAIGNAHGKY----KGeplLDFPRLDAIRQQ-AAIPLVLHGGSGISDDDFKRAIGLGI 227
Cdd:PRK07315  154 APIED---AKAMVE-TGIDFLAAGIGNIHGPYpenwEG---LDLDHLEKLTEAvPGFPIVLHGGSGIPDDQIQEAIKLGV 226

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1546372268 228 HKINFYT----GMSQAALSAVETRMAN-----RQPLYDEFAELLLGIeEAITDTVSEQMRIFGSAGR 285
Cdd:PRK07315  227 AKVNVNTecqiAFANATRKFARDYEANeaeydKKKLFDPRKFLAPGV-KAIQASVEERIDVFGSANK 292
PLN02858 PLN02858
fructose-bisphosphate aldolase
 5-285 1.90e-49

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 175.43  E-value: 1.90e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268    5 SLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLdSLVEAVKFEAARHDIPVVLNLDHG 84
Cdd:PLN02858  1101 STKELLLNAEKGGYAVGAFNVYNLEGIEAVVAAAEAEKSPAILQVHPGALKQGGI-PLVSCCIAAAEQASVPITVHFDHG 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   85 LHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGaLYGHADESLFTDPMMARDF 164
Cdd:PLN02858  1180 TSKHELLEALELGFDSVMVDGSHLSFTENISYTKSISSLAHSKGLMVEAELGRLSGTEDG-LTVEEYEAKLTDVDQAKEF 1258

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  165 VDRTGIDALAVAIGNAHGKY-KGEPLLDFPRLDAIRQQAA---IPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAA 240
Cdd:PLN02858  1259 IDETGIDALAVCIGNVHGKYpASGPNLRLDLLKELRALSSkkgVLLVLHGASGLPESLIKECIENGVRKFNVNTEVRTAY 1338

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 1546372268  241 LSAVetrmanRQPLYDEFAELLLGIEEAITDTVSEQMRIFGSAGR 285
Cdd:PLN02858  1339 MEAL------SSPKKTDLIDVMSAAKEAMKAVVAEKLRLFGSAGK 1377
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
3-244 2.89e-42

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 147.57  E-value: 2.89e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   3 LISLADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYIS---LDSLVE-AVKF-EAARHDIPV 77
Cdd:PRK07084    9 LVNTREMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVSKGARKYANatlLRYMAQgAVEYaKELGCPIPI 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  78 VLNLDHGLHFESVVRALRLGFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGGDEGGAlygHADESLFTD 157
Cdd:PRK07084   89 VLHLDHGDSFELCKDCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEV---SAEHHTYTQ 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 158 PMMARDFVDRTGIDALAVAIGNAHGKYK---GE--PLLDFPRLDAIRQQ-AAIPLVLHGGSGISDD----------DFKR 221
Cdd:PRK07084  166 PEEVEDFVKKTGVDSLAISIGTSHGAYKfkpGQcpPPLRFDILEEIEKRiPGFPIVLHGSSSVPQEyvktineyggKLKD 245

                         250       260
                  ....*....|....*....|...
gi 1546372268 222 AIGLGIHKinfytgMSQAALSAV 244
Cdd:PRK07084  246 AIGIPEEQ------LRKAAKSAV 262
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 13-244 5.42e-40

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 142.25  E-value: 5.42e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  13 AREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEV-HFKYIS---------------LDSLVEAVKFEAARHDIP 76
Cdd:cd00453     8 AKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGgASFIAGkgvksdvpqgaailgAISGAHHVHQMAEHYGVP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  77 VVLNLDH----------------GLHFESVVRALrlgFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAELGAVGG 140
Cdd:cd00453    88 VILHTDHcakkllpwidglldagEKHFAATGKPL---FSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELGCTGG 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 141 DEGGALYGHADES-LFTDPMMARDFVDRTG----IDALAVAIGNAHGKYK-GEPLLDFPRLDAIRQ---------QAAIP 205
Cdd:cd00453   165 EEDGVDNSHMDASaLYTQPEDVDYAYTELSkispRFTIAASFGNVHGVYKkGNVVLTPTILRDSQEyvskkhnlpHNSLN 244

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 1546372268 206 LVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAALSAV 244
Cdd:cd00453   245 FVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGV 283
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 6-250 3.51e-24

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 99.75  E-value: 3.51e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   6 LADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYI------------SLDSLVEAVKF--EAA 71
Cdd:cd00946     4 VLKLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYagkglknekqkaSIAGAIAAAHHvrSMA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  72 RH-DIPVVLNLDH----------GL------HFESVVRALrlgFSSVMFDGSTLEYEENIRQTREVVKMCHAVGVSVEAE 134
Cdd:cd00946    84 EHyGVPVVLHTDHcakkllpwfdGLleadeeYFKQHGEPL---FSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEME 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 135 LGAVGGDEGGALYGHAD-ESLFTDPmmaRDFVDrtGIDAL---------AVAIGNAHGKYKG-----EPLLDFPRLDAIR 199
Cdd:cd00946   161 IGITGGEEDGVDNSGVDnAELYTQP---EDVWY--VYEALskispnfsiAAAFGNVHGVYKPgnvklQPEILGEHQDYVR 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1546372268 200 QQAA------IPLVLHGGSGISDDDFKRAIGLGIHKINFYTGMSQAALSAVETRMAN 250
Cdd:cd00946   236 EKLGladdkpLYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLK 292
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 1-231 1.36e-23

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 98.33  E-value: 1.36e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268   1 MPLIS---LADGLAHAREHRYALGAFNVLDSHFLRALFAAAKQERSPFIINI----AEvhF---KYISLDSLVEAV---- 66
Cdd:PRK09197    1 PGVATgedYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFsnggAA--FiagKGVKDDGQGAAVlgai 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268  67 ---KFE---AARHDIPVVLNLDH----------GL------HFESVVRALrlgFSSVMFDGSTLEYEENIRQTREVVKMC 124
Cdd:PRK09197   79 agaKHVhevAEHYGVPVILHTDHcakkllpwidGLldagekHFAAGGKPL---FSSHMIDLSEEPLEENIEICSKYLERM 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1546372268 125 HAVGVSVEAELGAVGGDEGGALYGHAD-ESLFTDPmmarDFVDRTgIDAL---------AVAIGNAHGKYK-GEPLLDFP 193
Cdd:PRK09197  156 AKAGMTLEIELGVTGGEEDGVDNSHEDnSKLYTQP----EDVLYA-YEALgkisgrftiAASFGNVHGVYKpGNVKLRPE 230

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1546372268 194 RLDAIRQQAA---------IPLVLHGGSGISDDDFKRAIGLGIHKIN 231
Cdd:PRK09197  231 ILKDSQEYVSkkfglpakpFDFVFHGGSGSTLEEIREAVSYGVVKMN 277
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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