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Conserved domains on  [gi|1549734172|gb|RVK43228|]
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PQQ-dependent dehydrogenase, methanol/ethanol family [Sinorhizobium meliloti]

Protein Classification

methanol/ethanol family PQQ-dependent dehydrogenase( domain architecture ID 10178894)

methanol/ethanol family PQQ-dependent dehydrogenase similar to methanol dehydrogenase [cytochrome c] subunit 1 (also called large subunit alpha) that catalyzes the oxidation of primary alcohols including methanol

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PQQ_MDH cd10278
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ...
 36-599 0e+00

Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.


:

Pssm-ID: 199836 [Multi-domain]  Cd Length: 553  Bit Score: 989.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  36 WAIQTGDYANLRYSKLDQINKDNVGKLQVAWTFSTGVLRGHEGSPLVIGDLMYVHTPFPNTVYALDLSKDGQIVWKYEPK 115
Cdd:cd10278     1 WVMPGKDYANTRYSPLAQINKDNVKNLKVAWTFSTGVLRGHEGAPLVVGDTMYVVTPFPNNVYALDLNDPGKILWKYKPK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 116 QDPNVIPVMCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGISGGEFG 195
Cdd:cd10278    81 QDPSAVAVACCDVVNRGLAYADGKIFFNQLDGHLVALDAKTGKEVWKVKNGDPKVGETLTMAPLVVKDKVIVGISGGEFG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 196 VRGHVTAYSMADGKVLWRGYSMGPDSDTLIDPEKTTHLGKPVGKDSGLTTWEGDQWKIGGGTTWGWYSYDPEENLVYYGT 275
Cdd:cd10278   161 VRGYVTAYDLKTGKLVWRAYSTGPDKDVLIGPDFNPFNPHDGGKDLGLSTWPGDAWKIGGGTNWGWYSYDPKLNLVYYGT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 276 GNPSTWNPTQRPGDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDGKDRKLLTHFDRNGFGYTMDR 355
Cdd:cd10278   241 GNPGPWNPTQRPGDNKWSMTIFARDPDTGEAKWAYQMTPHDEWDYDGVNEMILVDQTVDGKKRKLLVHFDRNGFVYTLDR 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 356 VTGELLVAEKYDPTVNWaTEVVMdpksdKYGRPQVVAQYSTEQngeDTNTTGVCPAALGTKDQQPAAYSPKTELFYVPTN 435
Cdd:cd10278   321 TTGELLSAEKFDPVNNW-KGVDL-----KTGRPVKDPEKSTHM---DHNVTDICPSAMGGKDQQPSSYSPKTGLFYVPTN 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 436 HVCMDYEPFRVSYTAGQPYVGATLSMYPPKdsHGGMGNFIAWDNKEGKIKWSLPEPFSVWSGALATAGDVVFYGTLEGYL 515
Cdd:cd10278   392 HLCMDYEPFEVNYTAGQPYVGATLAMYPGP--GGHMGQFKAWDPVTGKTKWEIKERFPVWSGTLATAGGLVFYGTLDGWF 469

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 516 KAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGGWAGIGLAAGLTNPTEGLGAVGGYSALSNYTALGGTLT 595
Cdd:cd10278   470 KAVDAKTGKLLWKFKLPSGIIGNPITYKHDGKQYVAVLSGVGGWAGVGVAAGLRDPTAGLGAVGAFKDLPNYTQMGGTLY 549


                  ....
gi 1549734172 596 VFKL 599
Cdd:cd10278   550 VFSL 553
 
Name Accession Description Interval E-value
PQQ_MDH cd10278
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ...
 36-599 0e+00

Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.


Pssm-ID: 199836 [Multi-domain]  Cd Length: 553  Bit Score: 989.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  36 WAIQTGDYANLRYSKLDQINKDNVGKLQVAWTFSTGVLRGHEGSPLVIGDLMYVHTPFPNTVYALDLSKDGQIVWKYEPK 115
Cdd:cd10278     1 WVMPGKDYANTRYSPLAQINKDNVKNLKVAWTFSTGVLRGHEGAPLVVGDTMYVVTPFPNNVYALDLNDPGKILWKYKPK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 116 QDPNVIPVMCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGISGGEFG 195
Cdd:cd10278    81 QDPSAVAVACCDVVNRGLAYADGKIFFNQLDGHLVALDAKTGKEVWKVKNGDPKVGETLTMAPLVVKDKVIVGISGGEFG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 196 VRGHVTAYSMADGKVLWRGYSMGPDSDTLIDPEKTTHLGKPVGKDSGLTTWEGDQWKIGGGTTWGWYSYDPEENLVYYGT 275
Cdd:cd10278   161 VRGYVTAYDLKTGKLVWRAYSTGPDKDVLIGPDFNPFNPHDGGKDLGLSTWPGDAWKIGGGTNWGWYSYDPKLNLVYYGT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 276 GNPSTWNPTQRPGDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDGKDRKLLTHFDRNGFGYTMDR 355
Cdd:cd10278   241 GNPGPWNPTQRPGDNKWSMTIFARDPDTGEAKWAYQMTPHDEWDYDGVNEMILVDQTVDGKKRKLLVHFDRNGFVYTLDR 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 356 VTGELLVAEKYDPTVNWaTEVVMdpksdKYGRPQVVAQYSTEQngeDTNTTGVCPAALGTKDQQPAAYSPKTELFYVPTN 435
Cdd:cd10278   321 TTGELLSAEKFDPVNNW-KGVDL-----KTGRPVKDPEKSTHM---DHNVTDICPSAMGGKDQQPSSYSPKTGLFYVPTN 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 436 HVCMDYEPFRVSYTAGQPYVGATLSMYPPKdsHGGMGNFIAWDNKEGKIKWSLPEPFSVWSGALATAGDVVFYGTLEGYL 515
Cdd:cd10278   392 HLCMDYEPFEVNYTAGQPYVGATLAMYPGP--GGHMGQFKAWDPVTGKTKWEIKERFPVWSGTLATAGGLVFYGTLDGWF 469

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 516 KAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGGWAGIGLAAGLTNPTEGLGAVGGYSALSNYTALGGTLT 595
Cdd:cd10278   470 KAVDAKTGKLLWKFKLPSGIIGNPITYKHDGKQYVAVLSGVGGWAGVGVAAGLRDPTAGLGAVGAFKDLPNYTQMGGTLY 549


                  ....
gi 1549734172 596 VFKL 599
Cdd:cd10278   550 VFSL 553
PQQ_enz_alc_DH TIGR03075
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic ...
 16-558 0e+00

PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Genes in this family often are found adjacent to the PQQ biosynthesis genes themselves. An unusual, strained disulfide bond between adjacent Cys residues contributes to PQQ-binding, as does a Trp residue that is part of a PQQ enzyme repeat (see pfam01011). Characterized members include the dehydrogenase subunit of a membrane-anchored, three subunit alcohol (ethanol) dehydrogenase of Gluconobacter suboxydans, a homodimeric ethanol dehydrogenase in Pseudomonas aeruginosa, and the large subunit of an alpha2/beta2 heterotetrameric methanol dehydrogenase in Methylobacterium extorquens.


Pssm-ID: 274419 [Multi-domain]  Cd Length: 527  Bit Score: 871.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  16 GAQVAFANDELQKLIDDPNQWAIQTGDYANLRYSKLDQINKDNVGKLQVAWTFSTGVLRGHEGSPLVIGDLMYVHTPFPN 95
Cdd:TIGR03075   1 AAAAAVTNEDLLNDAKDPSDWLTYGGGYAGQRYSPLDQINTDNVKKLQPAWTFSLGKQRGQESQPLVVDGVMYVTTSYSR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  96 tVYALDlSKDGQIVWKYEPKQDPNVIPVMCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNT 175
Cdd:TIGR03075  81 -VYALD-AKTGKILWKYDPKLPDDIIPVMCCDVVNRGAALYDGKVFFGTLDARLVALDAKTGKVVWSKKNGDYKKGYTIT 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 176 ATVMPVKDKILVGISGGEFGVRGHVTAYSMADGKVLWRGYSMGPDSDTLidpEKTthlGKPVGKDSGLTTWEGDQWKIGG 255
Cdd:TIGR03075 159 AAPLVVKGKVITGISGGEFGVRGYVTAYDAKTGKLVWRRYTVPGDMGYL---KKT---GKPVGGDPGAKTWPGDAWKTGG 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 256 GTTWGWYSYDPEENLVYYGTGNPSTWNPTQRPGDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDG 335
Cdd:TIGR03075 233 GATWGTGSYDPETNLIYFGTGNPAPWNSHLRPGDNLYTSSIVARDPDTGKIKWHYQTTPHDEWDYDGVNEMILFDLKKDG 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 336 KDRKLLTHFDRNGFGYTMDRVTGELLVAEKYDPTVNWATEVVMDPksdkyGRPQVVAQYSTEQnGEDTNTTGVCPAALGT 415
Cdd:TIGR03075 313 KPRKLLAHADRNGFFYVLDRTNGKLLSAEPFVDKVNWATGVDLKT-----GRPIEVPEARSTD-GKKGKPVEVCPGFLGG 386

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 416 KDQQPAAYSPKTELFYVPTNHVCMDYEPFRVSYTAGQPYVGATLSMYPPKDSHggMGNFIAWDNKEGKIKWSLPEPFSVW 495
Cdd:TIGR03075 387 KNWQPMAYSPKTGLFYVPANHVCMDYWPEKVSYKKGAAYLGAGFTIKPPPDDH--IGSLIAWDPITGKIVWEHKEDFPLW 464

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1549734172 496 SGALATAGDVVFYGTLEGYLKAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGG 558
Cdd:TIGR03075 465 GGVLATAGDLVFTGTLEGYFKAFDAKTGEELWKFKTGSGIVGPPVTYEQDGKQYVAVLSGWGG 527
Gcd COG4993
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
32-600 0e+00

Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];


Pssm-ID: 444017 [Multi-domain]  Cd Length: 515  Bit Score: 748.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  32 DPNQWAIQTGDYANLRYSKLDQINKDNVGKLQVAWTFSTGVL--RGHEGSPLVIGDLMYVHTPFpNTVYALDLsKDGQIV 109
Cdd:COG4993     1 DPGDWLAYGGDYAGQRYSPLDQINPDNVKKLKVAWTFSTGDLpeRGHEATPLVVDGVLYVCTPH-NRVFALDA-ATGKEL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 110 WKYEPKQDPNVipvMCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGI 189
Cdd:COG4993    79 WRYDPKLPDDA---ACCDVVNRGVAYYDGRIFLGTLDGRLVALDAKTGKVCWDVKVGDPKKGYTITSAPLVVKDKVIVGG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 190 SGGEFGVRGHVTAYSMADGKVLWRGYSmGPDSdtlidpektthlgkpvgKDSGLTTWE-GDQWKIGGGTTWGWYSYDPEE 268
Cdd:COG4993   156 SGGEFGPRGVVRAYDARTGKLVWRFDT-IPDP-----------------GEPGAETWPpGDTWKRGGGNVWGTMSYDPEL 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 269 NLVYYGTGNPST-WNPTQRPGDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDGKDRKLLTHFDRN 347
Cdd:COG4993   218 GLVYLPTGNPAPdWNGGQRPGDNLYSSSIVALDADTGELKWHYQTVPHDLWDYDGPNEPILVDLPVDGKTRKALVQATKN 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 348 GFGYTMDRVTGELLVAEKYDPTVNWATEVVMDPKSdkygrPQVVAqysteqNGEDTNTTGVCPAALGTKDQQPAAYSPKT 427
Cdd:COG4993   298 GFIYVLDRETGEPLVTQPFVKPPNWATEIDMWGAT-----PIQTP------PSLDGKTTLICPGALGGKNWGPAAYDPET 366

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 428 ELFYVPTNHVCMDYEPFRVSYTAGQPYVGATLSMYPPKDSHggMGNFIAWDNKEGKIKWSLPEPFSVWSGALATAGDVVF 507
Cdd:COG4993   367 GLLYVPANELCMDYELVPREYQAGAPYLGATLTMYPCPAPP--WGTLTAIDLNTGKIVWQVPLGFPNWGGPLATAGGLVF 444

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 508 YGTLEGYLKAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGGWAGIGLaagltnpteglgavggysalsnY 587
Cdd:COG4993   445 IGTLDGYLRAFDAKTGKELWKFRLPSGGQATPMTYEVDGKQYVAVAAGGGGWLGLGL----------------------Y 502

                         570
                  ....*....|...
gi 1549734172 588 TALGGTLTVFKLP 600
Cdd:COG4993   503 TPQGDYLIAFALP 515
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 63-212 1.88e-12

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 67.04  E-value: 1.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  63 QVAWTFSTGVLRGheGSPLVIGDLMYVHTPFpNTVYALDLSkDGQIVWKYEPKQDPNVIPVMccdtvnrgvayADNKIFL 142
Cdd:pfam13360  14 AELWRVDLETGLG--GGVAVDGGRLFVATGG-GQLVALDAA-TGKLLWRQTLSGEVLGAPLV-----------AGGRVFV 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 143 HQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGISGGEfgvrghVTAYSMADGKVLW 212
Cdd:pfam13360  79 VAGDGSLIALDAADGRRLWSYQRSGEPLALRSSGSPAVVGDTVVAGFSSGK------LVALDPATGKVRW 142
PRK11138 PRK11138
outer membrane biogenesis protein BamB; Provisional
 63-213 5.84e-05

outer membrane biogenesis protein BamB; Provisional


Pssm-ID: 236857 [Multi-domain]  Cd Length: 394  Bit Score: 45.69  E-value: 5.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  63 QVAWTFSTGVLRGHEGS---PLVIGDLMYVHTPFpNTVYALDLsKDGQIVWKYEPKQDPNVIPVMCCDTVNRGVAYADNK 139
Cdd:PRK11138   45 TTVWSTSVGDGVGDYYSrlhPAVAYNKVYAADRA-GLVKALDA-DTGKEIWSVDLSEKDGWFSKNKSALLSGGVTVAGGK 122

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1549734172 140 IFLHQADTTVVALDAKTGKVIWSVKngdaTKGETNTAtvmPVKDKILVGISGGefgvRGHVTAYSMADGKVLWR 213
Cdd:PRK11138  123 VYIGSEKGQVYALNAEDGEVAWQTK----VAGEALSR---PVVSDGLVLVHTS----NGMLQALNESDGAVKWT 185
 
Name Accession Description Interval E-value
PQQ_MDH cd10278
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ...
 36-599 0e+00

Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.


Pssm-ID: 199836 [Multi-domain]  Cd Length: 553  Bit Score: 989.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  36 WAIQTGDYANLRYSKLDQINKDNVGKLQVAWTFSTGVLRGHEGSPLVIGDLMYVHTPFPNTVYALDLSKDGQIVWKYEPK 115
Cdd:cd10278     1 WVMPGKDYANTRYSPLAQINKDNVKNLKVAWTFSTGVLRGHEGAPLVVGDTMYVVTPFPNNVYALDLNDPGKILWKYKPK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 116 QDPNVIPVMCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGISGGEFG 195
Cdd:cd10278    81 QDPSAVAVACCDVVNRGLAYADGKIFFNQLDGHLVALDAKTGKEVWKVKNGDPKVGETLTMAPLVVKDKVIVGISGGEFG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 196 VRGHVTAYSMADGKVLWRGYSMGPDSDTLIDPEKTTHLGKPVGKDSGLTTWEGDQWKIGGGTTWGWYSYDPEENLVYYGT 275
Cdd:cd10278   161 VRGYVTAYDLKTGKLVWRAYSTGPDKDVLIGPDFNPFNPHDGGKDLGLSTWPGDAWKIGGGTNWGWYSYDPKLNLVYYGT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 276 GNPSTWNPTQRPGDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDGKDRKLLTHFDRNGFGYTMDR 355
Cdd:cd10278   241 GNPGPWNPTQRPGDNKWSMTIFARDPDTGEAKWAYQMTPHDEWDYDGVNEMILVDQTVDGKKRKLLVHFDRNGFVYTLDR 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 356 VTGELLVAEKYDPTVNWaTEVVMdpksdKYGRPQVVAQYSTEQngeDTNTTGVCPAALGTKDQQPAAYSPKTELFYVPTN 435
Cdd:cd10278   321 TTGELLSAEKFDPVNNW-KGVDL-----KTGRPVKDPEKSTHM---DHNVTDICPSAMGGKDQQPSSYSPKTGLFYVPTN 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 436 HVCMDYEPFRVSYTAGQPYVGATLSMYPPKdsHGGMGNFIAWDNKEGKIKWSLPEPFSVWSGALATAGDVVFYGTLEGYL 515
Cdd:cd10278   392 HLCMDYEPFEVNYTAGQPYVGATLAMYPGP--GGHMGQFKAWDPVTGKTKWEIKERFPVWSGTLATAGGLVFYGTLDGWF 469

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 516 KAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGGWAGIGLAAGLTNPTEGLGAVGGYSALSNYTALGGTLT 595
Cdd:cd10278   470 KAVDAKTGKLLWKFKLPSGIIGNPITYKHDGKQYVAVLSGVGGWAGVGVAAGLRDPTAGLGAVGAFKDLPNYTQMGGTLY 549


                  ....
gi 1549734172 596 VFKL 599
Cdd:cd10278   550 VFSL 553
PQQ_enz_alc_DH TIGR03075
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic ...
 16-558 0e+00

PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Genes in this family often are found adjacent to the PQQ biosynthesis genes themselves. An unusual, strained disulfide bond between adjacent Cys residues contributes to PQQ-binding, as does a Trp residue that is part of a PQQ enzyme repeat (see pfam01011). Characterized members include the dehydrogenase subunit of a membrane-anchored, three subunit alcohol (ethanol) dehydrogenase of Gluconobacter suboxydans, a homodimeric ethanol dehydrogenase in Pseudomonas aeruginosa, and the large subunit of an alpha2/beta2 heterotetrameric methanol dehydrogenase in Methylobacterium extorquens.


Pssm-ID: 274419 [Multi-domain]  Cd Length: 527  Bit Score: 871.23  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  16 GAQVAFANDELQKLIDDPNQWAIQTGDYANLRYSKLDQINKDNVGKLQVAWTFSTGVLRGHEGSPLVIGDLMYVHTPFPN 95
Cdd:TIGR03075   1 AAAAAVTNEDLLNDAKDPSDWLTYGGGYAGQRYSPLDQINTDNVKKLQPAWTFSLGKQRGQESQPLVVDGVMYVTTSYSR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  96 tVYALDlSKDGQIVWKYEPKQDPNVIPVMCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNT 175
Cdd:TIGR03075  81 -VYALD-AKTGKILWKYDPKLPDDIIPVMCCDVVNRGAALYDGKVFFGTLDARLVALDAKTGKVVWSKKNGDYKKGYTIT 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 176 ATVMPVKDKILVGISGGEFGVRGHVTAYSMADGKVLWRGYSMGPDSDTLidpEKTthlGKPVGKDSGLTTWEGDQWKIGG 255
Cdd:TIGR03075 159 AAPLVVKGKVITGISGGEFGVRGYVTAYDAKTGKLVWRRYTVPGDMGYL---KKT---GKPVGGDPGAKTWPGDAWKTGG 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 256 GTTWGWYSYDPEENLVYYGTGNPSTWNPTQRPGDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDG 335
Cdd:TIGR03075 233 GATWGTGSYDPETNLIYFGTGNPAPWNSHLRPGDNLYTSSIVARDPDTGKIKWHYQTTPHDEWDYDGVNEMILFDLKKDG 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 336 KDRKLLTHFDRNGFGYTMDRVTGELLVAEKYDPTVNWATEVVMDPksdkyGRPQVVAQYSTEQnGEDTNTTGVCPAALGT 415
Cdd:TIGR03075 313 KPRKLLAHADRNGFFYVLDRTNGKLLSAEPFVDKVNWATGVDLKT-----GRPIEVPEARSTD-GKKGKPVEVCPGFLGG 386

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 416 KDQQPAAYSPKTELFYVPTNHVCMDYEPFRVSYTAGQPYVGATLSMYPPKDSHggMGNFIAWDNKEGKIKWSLPEPFSVW 495
Cdd:TIGR03075 387 KNWQPMAYSPKTGLFYVPANHVCMDYWPEKVSYKKGAAYLGAGFTIKPPPDDH--IGSLIAWDPITGKIVWEHKEDFPLW 464

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1549734172 496 SGALATAGDVVFYGTLEGYLKAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGG 558
Cdd:TIGR03075 465 GGVLATAGDLVFTGTLEGYFKAFDAKTGEELWKFKTGSGIVGPPVTYEQDGKQYVAVLSGWGG 527
Gcd COG4993
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
32-600 0e+00

Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];


Pssm-ID: 444017 [Multi-domain]  Cd Length: 515  Bit Score: 748.91  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  32 DPNQWAIQTGDYANLRYSKLDQINKDNVGKLQVAWTFSTGVL--RGHEGSPLVIGDLMYVHTPFpNTVYALDLsKDGQIV 109
Cdd:COG4993     1 DPGDWLAYGGDYAGQRYSPLDQINPDNVKKLKVAWTFSTGDLpeRGHEATPLVVDGVLYVCTPH-NRVFALDA-ATGKEL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 110 WKYEPKQDPNVipvMCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGI 189
Cdd:COG4993    79 WRYDPKLPDDA---ACCDVVNRGVAYYDGRIFLGTLDGRLVALDAKTGKVCWDVKVGDPKKGYTITSAPLVVKDKVIVGG 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 190 SGGEFGVRGHVTAYSMADGKVLWRGYSmGPDSdtlidpektthlgkpvgKDSGLTTWE-GDQWKIGGGTTWGWYSYDPEE 268
Cdd:COG4993   156 SGGEFGPRGVVRAYDARTGKLVWRFDT-IPDP-----------------GEPGAETWPpGDTWKRGGGNVWGTMSYDPEL 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 269 NLVYYGTGNPST-WNPTQRPGDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDGKDRKLLTHFDRN 347
Cdd:COG4993   218 GLVYLPTGNPAPdWNGGQRPGDNLYSSSIVALDADTGELKWHYQTVPHDLWDYDGPNEPILVDLPVDGKTRKALVQATKN 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 348 GFGYTMDRVTGELLVAEKYDPTVNWATEVVMDPKSdkygrPQVVAqysteqNGEDTNTTGVCPAALGTKDQQPAAYSPKT 427
Cdd:COG4993   298 GFIYVLDRETGEPLVTQPFVKPPNWATEIDMWGAT-----PIQTP------PSLDGKTTLICPGALGGKNWGPAAYDPET 366

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 428 ELFYVPTNHVCMDYEPFRVSYTAGQPYVGATLSMYPPKDSHggMGNFIAWDNKEGKIKWSLPEPFSVWSGALATAGDVVF 507
Cdd:COG4993   367 GLLYVPANELCMDYELVPREYQAGAPYLGATLTMYPCPAPP--WGTLTAIDLNTGKIVWQVPLGFPNWGGPLATAGGLVF 444

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 508 YGTLEGYLKAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGGWAGIGLaagltnpteglgavggysalsnY 587
Cdd:COG4993   445 IGTLDGYLRAFDAKTGKELWKFRLPSGGQATPMTYEVDGKQYVAVAAGGGGWLGLGL----------------------Y 502

                         570
                  ....*....|...
gi 1549734172 588 TALGGTLTVFKLP 600
Cdd:COG4993   503 TPQGDYLIAFALP 515
PQQ_ADH_I cd10277
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ...
 32-599 0e+00

Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.


Pssm-ID: 199835 [Multi-domain]  Cd Length: 529  Bit Score: 534.18  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  32 DPNQWAIQTGDYANLRYSKLDQINKDNVGKLQVAWTFSTGVL-RGHEGSPLVIGDLMYVHTPFpNTVYALDlSKDGQIVW 110
Cdd:cd10277     7 ETGNWLTYGRGYNGQRYSPLKQINTDNVKNLVPAWSFSFGGKqRGQESQPIVNDGVMYVTTSY-NRVFAID-AKTGKELW 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 111 KYEPKQDPNVIPvmCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGIS 190
Cdd:cd10277    85 KYKHRLPEDIRP--CCDVVNRGVALYGDKVYFGTLDAHLVALDAKTGKVVWKKKVADYKAGYSMTLAPLVVKGKVIVGVS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 191 GGEFGVRGHVTAYSMADGKVLWRGYSM-GPdsdtlidpektthlGKPVGKDsgltTWEGDQWKIGGGTTWGWYSYDPEEN 269
Cdd:cd10277   163 GGEFGVRGFIAALDAETGKEVWRTYTVpGP--------------GEPGSTD----TWPGDAWKTGGGATWLTGTYDPETN 224

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 270 LVYYGTGNPSTWNPTQRPGDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDGKDRKLLTHFDRNGF 349
Cdd:cd10277   225 LLYWGVGNPAPWNGDLRPGDNLYTSSVLALDPDTGKIKWHYQYTPNDTWDYDGVNEPVLFDYTKNGKPVKALVHADRNGF 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 350 GYTMDRVTGELLVAEKYDPTVNWATevvMDPKSdkyGRPqvvaQYSTEQNGEDTNTTG-VCPAALGTKDQQPAAYSPKTE 428
Cdd:cd10277   305 FYVLDRTNGKLIWATPFVKKITWAS---IDLKT---GRP----IYDEDKVPPKKGKTVdFCPSFLGGKNWPPMAYSPDTG 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 429 LFYVPTNHVCMDYEPFRVSYTAGQPYVGATLSMYPPKDSHggMGNFIAWDNKEGKIKWSLPEPFSVWSGALATAGDVVFY 508
Cdd:cd10277   375 LFYVPANHWCMDLTGEPVSYKKGAAYLGAGFTIKPPFEDH--IGELQAIDPTTGKKVWEHKTPLPLWGGVLTTAGGLVFT 452

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 509 GTLEGYLKAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGGWAGIglaagltnpteglgaVGGYSALSNYT 588
Cdd:cd10277   453 GTPDGYFRAFDAKTGKELWEFQTGSGIIGPPVTWEVDGKQYVAVLSGWGGAAPL---------------WGGDMAKLLKN 517

                         570
                  ....*....|..
gi 1549734172 589 A-LGGTLTVFKL 599
Cdd:cd10277   518 VpQGGSLWVFAL 529
PQQ_ADH_II cd10279
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ...
 35-599 1.18e-148

PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.


Pssm-ID: 199837 [Multi-domain]  Cd Length: 549  Bit Score: 440.16  E-value: 1.18e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  35 QWAIQTGDYANLRYSKLDQINKDNVGKLQVAWTFSTGVLRGHEGSPLVIGDLMYVHTPFpNTVYALDLsKDGQIVWKYEP 114
Cdd:cd10279     2 NWLSYGRDYDEQRFSPLTQINRSNVGQLGLAWYFDLDTNRGQEATPLVVDGVMYVSGPW-SVVYALDA-RTGKLLWQYDP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 115 KQDPNVIPVMCCDTVNRGVAYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGISGGEF 194
Cdd:cd10279    80 EVDRESGRKACCDVVNRGVAVWDGKVFVGTLDGRLIALDAKTGKEVWSVDTIDPRKPYTITGAPRVAKGKVVIGNGGAEF 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 195 GVRGHVTAYSMADGKVLWRGYSMgPDsdtliDPEKTthLGKPVGKDSGLTTWEGDQWKIG-GGTTWGWYSYDPEENLVYY 273
Cdd:cd10279   160 GVRGYVSAYDAETGKLVWRFYTV-PG-----NPAKP--FEHASLEAAAATWWTGEWWRTGgGGTVWDSITYDPELDLLYI 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 274 GTGNPSTWNPTQRP---GDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDGKDRKLLTHFDRNGFG 350
Cdd:cd10279   232 GTGNGSPWNRKVRSpggGDNLFLSSIVALDADTGRYKWHYQTTPGDTWDYTATQPIILADLEIDGKPRKVLMHAPKNGFF 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 351 YTMDRVTGELLVAEKYDPtVNWATEVvmDPKSdkyGRPQVVAQYSTEQNGEDtnttgVCPAALGTKDQQPAAYSPKTELF 430
Cdd:cd10279   312 YVLDRATGKLLSAEPFVP-VNWATGI--DLKT---GRPIENPEARYTKGPKL-----VFPGPLGAHNWHPMSYNPDTGLV 380

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 431 YVPTNHVCMDY--EPFRVSYTAGQPYVGATLSMYPPKDSHGGM------GNFIAWDNKEGKIKWSLPEPFSVWSGALATA 502
Cdd:cd10279   381 YIPAQEIPAVYedDPGDFGYNPLGWNTGITPDATPPPAAAKRAlrkatrGRLVAWDPVTQKAAWRVEHPGPWNGGVLATA 460

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 503 GDVVFYGTLEGYLKAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGGwagiglaagltnpteGLGAVGGYS 582
Cdd:cd10279   461 GNLVFQGTADGELAAYDARTGEKLWSFDTGSGIVAAPMTYSVDGEQYVAVLAGWGG---------------AGALSGGPP 525

                         570
                  ....*....|....*..
gi 1549734172 583 ALSNYTALGGTLTVFKL 599
Cdd:cd10279   526 GAAGKVQNPGRLLVFKL 542
PQQ_DH_like cd00216
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases ...
 56-598 2.28e-135

PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases with pyrroloquinoline quinone (PQQ) as a cofactor, such as ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller, and the family also includes distantly related proteins which are not enzymatically active and do not bind PQQ.


Pssm-ID: 199833 [Multi-domain]  Cd Length: 434  Bit Score: 401.99  E-value: 2.28e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  56 KDNVGKLQVAWTFSTGV--LRGHEGSPLVIGDLMYVHTPFpNTVYALDLsKDGQIVWKYEPKQDPNVIpVMCCDTVNRGV 133
Cdd:cd00216     1 ADNVFQLTPAWSFSTGDggNRGSELTPIVVDGVMYATTSF-SRVFALDA-DDGKEIWSYDPALKDGWF-EACCDLVNRGV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 134 AYADNKIFLHQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGISGGEFGVRGHVTAYSMADGKVLWR 213
Cdd:cd00216    78 AVWGGKVYIGVLDGRVYALNAETGKVAWKVKNADVLGGYTATSAPVVVDGLVIIGSSGDEFGVRGYLTAYDVATGEEKWR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 214 GYSMGPDSDTLIDpektthlGKPVGKDSGLTTWEGDQWKIGGGTTWGWYSYDPEENLVYYGTGNPSTWNPT--QRPGDNR 291
Cdd:cd00216   158 FYLVMPDPNLLPG-------KDSTVTDRNTPTGDEHTWTSGGGTGWSSAAYDAELNLIYVGGGNPTPWNWGgnRTPGDNL 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 292 WSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEMILTEQQIDGKDRKLLTHFDRNGFGYTMDRVTGELLVAEKYDPTvn 371
Cdd:cd00216   231 YTSSIVAVNADTGEMKWQYQTTPHDAWDYDGDNTPVLADIKVKGKKVKVLFAPAKNGNFYVLDRRNGELVSARPLVPD-- 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 372 watevvmdpksdkygrpqvvaqysteqngedtnttgvcpaalgtkdqqpaAYSPKTELFYVPTNhvcmdyepfrvsytag 451
Cdd:cd00216   309 --------------------------------------------------SYDPDRELFYVPAN---------------- 322

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 452 qpyvgatlsmyppkdshggmGNFIAWDNKEGKIKWSLPEPFSVWSGALATAGDVVFYGTLEGYLKAVDAATGKELYRFKT 531
Cdd:cd00216   323 --------------------GRIMALDPVTGVVVWEKSELHPLLGGPLSTAGNLVFVGTSDGYLKAYNADTGEKLWQQKV 382

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1549734172 532 PSGVIGNVMTYAREGKQYVAVLSGVGGWAGIGlaagltnpteglgavGGYSALSNYTALGGTLTVFK 598
Cdd:cd00216   383 PSGFQAEPVTYEVDGEQYVLIQAGGGGAFPLW---------------GGMADLTRGTQMGGTVVVYK 434
PQQ_mGDH cd10280
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes ...
 41-561 1.04e-71

Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes belongs to the dehydrogenase family with pyrroloquinoline quinone (PQQ) as cofactor, and is the only subfamily that is bound to the membrane. Glucose dehydrogenase converts D-glucose to D-glucono-1,5-lactone in a reaction that is coupled with the respiratory chain in the periplasmic oxidation of sugars and alcohols in gram-negative bacteria. Ubiquinone functions as the electron acceptor. The alignment model contains an 8-bladed beta-propeller.


Pssm-ID: 199838 [Multi-domain]  Cd Length: 616  Bit Score: 242.10  E-value: 1.04e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  41 GDYANLRYSKLDQINKDNVGKLQVAWTFSTGVLRGH-------EGSPLVIGDLMYVHTPFpNTVYALDLSKdGQIVWKYE 113
Cdd:cd10280     6 GDPGGTRYSPLDQITPDNVGKLKVAWTYHTGDLPGPdgnegtfEATPLKVGGTLYLCTPH-NRVIALDAAT-GKELWRFD 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 114 PKQDPNVIPVMccdTVNRGVAY---------ADNKIFLHQADTTVVALDAKTGKVIWS----------VKNGDATKGE-T 173
Cdd:cd10280    84 PKAGADAAPGH---QTCRGVSYwedgaaaaaCARRIFFGTGDARLIALDARTGKPCPDfgdngvvdlrEGLGRVKPGFyS 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 174 NTATVMPVKDKILVGISGGEF----GVRGHVTAYSMADGKVLWrgysmgpdsdtlidpekTTHLGKPVGkDSGLTTweGD 249
Cdd:cd10280   161 STSPPTVYGDLVIVGSAVADNqavdAPSGVIRAFDVRTGKLVW-----------------AFDTIPPPG-EAGPDT--AG 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 250 QWK-IGGGTTWGWYSYDPEENLVYYGTGNPST--WNpTQRPGDNRWSMTIFARDVDTGMAKWLYQMTPHDEWDYDGVNEM 326
Cdd:cd10280   221 AWYtRGGPNVWAGMSADEKLGLVYLPTGSATPdfYG-GDRPGDNLFANSLVALDAATGKRRWHFQTVHHDLWDYDLPAQP 299

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 327 ILTEQQIDGKDRKLLTHFDRNGFGYTMDRVTGELLVA-------------EKYDPT-------VNWATEVVMDpkSDKYG 386
Cdd:cd10280   300 TLVDVPRDGKTVPAVAQPTKQGFVFVLDRRTGKPLWPveerpvpqgdvpgERTSPTqpfptlpPPFARQGLTE--DDMWG 377

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 387 R-P----QVVAQYSTEQNG-----EDTNTTGVCPAALGTKDQQPAAYSPKTELFYVPTNHVCM--------DYEPFRVSY 448
Cdd:cd10280   378 AtPfdqlACRIQFRSLRYEglftpPSLDGTLIFPGNDGGANWGGAAVDPERGILYVNSNRLPFviqlvpraPGDPAGVAG 457

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 449 TAGQPYVGATLSMYPPKDSHGGMGNFI----------------AWDNKEGKIKWS-------------LPEPFSVWS--- 496
Cdd:cd10280   458 GGEGGGGGGGPSPQAGTPYGVGRGRFLsplglpcqappwgtltAIDLNTGKILWQvplgtvpdlgpkgIPLPIPTGTpnl 537

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1549734172 497 -GALATAGDVVFYG-TLEGYLKAVDAATGKELYRFKTPSGVIGNVMTYAREGKQYVAVLSGVGGWAG 561
Cdd:cd10280   538 gGPVVTAGGLVFIAaTQDNYLRAFDKATGKELWEARLPAGGQATPMTYEVDGKQYVVIAAGGHGSLG 604
BamB_YfgL cd10276
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ...
 61-220 2.51e-13

Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.


Pssm-ID: 199834 [Multi-domain]  Cd Length: 358  Bit Score: 71.59  E-value: 2.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  61 KLQVAWTFSTG--VLRGHEGSPLVIGDLMYVHTPFpNTVYALDlSKDGQIVWKYEPKQDPNVIPvmccdtvnrGVAYADN 138
Cdd:cd10276    13 DPEVLWSKSVGngGMAGIDLTPVVAGDMVYAADAN-GQVSAFN-ATTGKIIWETSLSGKGFLGG---------TPAVGNG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 139 KIFLHQADTTVVALDAKTGKVIWsvkNGDATKGETNTATVMpVKDKILVGISGGEfgvrghVTAYSMADGKVLWRGYSMG 218
Cdd:cd10276    82 KIFVGTESGYLYALDAKDGSELW---RTEVSDSQLLSPPTY-ADGKIYVGTGDGR------LYYCNAETGKVVWNRTSTA 151


                  ..
gi 1549734172 219 PD 220
Cdd:cd10276   152 PE 153
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 63-212 1.88e-12

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 67.04  E-value: 1.88e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  63 QVAWTFSTGVLRGheGSPLVIGDLMYVHTPFpNTVYALDLSkDGQIVWKYEPKQDPNVIPVMccdtvnrgvayADNKIFL 142
Cdd:pfam13360  14 AELWRVDLETGLG--GGVAVDGGRLFVATGG-GQLVALDAA-TGKLLWRQTLSGEVLGAPLV-----------AGGRVFV 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 143 HQADTTVVALDAKTGKVIWSVKNGDATKGETNTATVMPVKDKILVGISGGEfgvrghVTAYSMADGKVLW 212
Cdd:pfam13360  79 VAGDGSLIALDAADGRRLWSYQRSGEPLALRSSGSPAVVGDTVVAGFSSGK------LVALDPATGKVRW 142
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 61-213 2.70e-11

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 65.61  E-value: 2.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  61 KLQVAWTFSTGVLRGHEGSPL---VIGDLMYVHTPFpNTVYALDLsKDGQIVWKYEPKQDpnvipvmccdtVNRGVAYAD 137
Cdd:COG1520    31 KVKQLWSASVGDGVGKGYSRLapaVAGDRVYAADAD-GRVAALDA-ATGKELWRVDLGEP-----------LSGGVGADG 97

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1549734172 138 NKIFLHQADTTVVALDAKTGKVIWSVKngdaTKGETNTAtvmPVkdkilvgISGGEFGVR---GHVTAYSMADGKVLWR 213
Cdd:COG1520    98 GLVVVGTEDGEVIALDADDGEELWRAR----LSSEVLAA---PA-------VAGGRVVVRtgdGRVYALDAATGERLWS 162
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 57-224 1.01e-09

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 60.72  E-value: 1.01e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  57 DNVGKLQVAWTFSTGVLRGHEGSPLVI---GDLMYVHTPFpNTVYALDLsKDGQIVWKYEPKQDpnvipvmccdtVNRGV 133
Cdd:TIGR03300  35 QPTVKVDQVWSASVGDGVGHYYLRLQPavaGGKVYAADAD-GTVAALDA-ETGKRLWRVDLDER-----------LSGGV 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 134 AYADNKIFLHQADTTVVALDAKTGKVIWSVKngdaTKGETNTATVmpVKDKILVGISGgefgvRGHVTAYSMADGKVLWR 213
Cdd:TIGR03300 102 GADGGLVFVGTEKGEVIALDAEDGKELWRAK----LSSEVLSPPL--VANGLVVVRTN-----DGRLTALDAATGERLWT 170

                         170
                  ....*....|.
gi 1549734172 214 gYSMGPDSDTL 224
Cdd:TIGR03300 171 -YSRVTPPLTL 180
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 78-212 2.48e-08

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 55.10  E-value: 2.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  78 GSPLVIGDLMYVHTPfPNTVYALDlSKDGQIVWKYEPKQDPNVIpvmccdTVNRGVAYADNKIFLHQADTTVVALDAKTG 157
Cdd:pfam13360  67 GAPLVAGGRVFVVAG-DGSLIALD-AADGRRLWSYQRSGEPLAL------RSSGSPAVVGDTVVAGFSSGKLVALDPATG 138

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1549734172 158 KVIWSVKNGdATKGETN-------TATVMPVKDKILVGisggefGVRGHVTAYSMADGKVLW 212
Cdd:pfam13360 139 KVRWEAPLA-APRGTNElerlvdiTGTPVVAGGRVFAS------AYQGRLVAFDAATGRRLW 193
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 96-213 6.27e-08

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 53.95  E-value: 6.27e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  96 TVYALDLsKDGQIVWKYEPKQDPNVipvmccdtvnrGVAYADNKIFLHQADTTVVALDAKTGKVIWSVkngdATKGETNT 175
Cdd:pfam13360   4 VVTALDA-ATGAELWRVDLETGLGG-----------GVAVDGGRLFVATGGGQLVALDAATGKLLWRQ----TLSGEVLG 67

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1549734172 176 ATVmpVKDKILVGISGGefgvrGHVTAYSMADGKVLWR 213
Cdd:pfam13360  68 APL--VAGGRVFVVAGD-----GSLIALDAADGRRLWS 98
PQQ pfam01011
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ...
 138-171 3.05e-06

PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.


Pssm-ID: 395799 [Multi-domain]  Cd Length: 36  Bit Score: 44.10  E-value: 3.05e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1549734172 138 NKIFLHQADTTVVALDAKTGKVIWSVKNGDATKG 171
Cdd:pfam01011   1 GTVYLGSDDGYLYALDAETGKVLWSFKTGGAVLS 34
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 78-188 7.71e-06

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 48.39  E-value: 7.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  78 GSPLVIGDLMYVhTPFPNTVYALDLSkDGQIVWKYEPkqdpnvipvmccdTVNRGVAYADNKIFLHQADTTVVALDAKTG 157
Cdd:TIGR03300 235 GDPVVDGGQVYA-VSYQGRVAALDLR-SGRVLWKRDA-------------SSYQGPAVDDNRLYVTDADGVVVALDRRSG 299

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1549734172 158 KVIWsvKNgDATKGETNTATVMpVKDKILVG 188
Cdd:TIGR03300 300 SELW--KN-DELKYRQLTAPAV-LGGYLVVG 326
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 469-536 2.17e-05

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 46.85  E-value: 2.17e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 469 GGMGNFIAWDNKEGKIKW--SLPEPFSvwsGALATAGDVVFYGTLEGYLKAVDAATGKELYRFKTPSGVI 536
Cdd:TIGR03300  72 DADGTVAALDAETGKRLWrvDLDERLS---GGVGADGGLVFVGTEKGEVIALDAEDGKELWRAKLSSEVL 138
PRK11138 PRK11138
outer membrane biogenesis protein BamB; Provisional
 63-213 5.84e-05

outer membrane biogenesis protein BamB; Provisional


Pssm-ID: 236857 [Multi-domain]  Cd Length: 394  Bit Score: 45.69  E-value: 5.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  63 QVAWTFSTGVLRGHEGS---PLVIGDLMYVHTPFpNTVYALDLsKDGQIVWKYEPKQDPNVIPVMCCDTVNRGVAYADNK 139
Cdd:PRK11138   45 TTVWSTSVGDGVGDYYSrlhPAVAYNKVYAADRA-GLVKALDA-DTGKEIWSVDLSEKDGWFSKNKSALLSGGVTVAGGK 122

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1549734172 140 IFLHQADTTVVALDAKTGKVIWSVKngdaTKGETNTAtvmPVKDKILVGISGGefgvRGHVTAYSMADGKVLWR 213
Cdd:PRK11138  123 VYIGSEKGQVYALNAEDGEVAWQTK----VAGEALSR---PVVSDGLVLVHTS----NGMLQALNESDGAVKWT 185
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 79-213 1.03e-04

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 44.80  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  79 SPLVIGDLMYVHTpFPNTVYALDlSKDGQIVWKYEpkqdpNVIPVMccdTVnRG---VAYADNKIFLHQADTTVVALDAK 155
Cdd:COG1520   132 APAVAGGRVVVRT-GDGRVYALD-AATGERLWSYQ-----RPVPAL---TL-RGtssPVIVGGAVLVGFANGKLVALDLA 200

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1549734172 156 TGKVIWSVKNGDAtKGET-----NTATVMPVkdkilvgISGGE-FGV--RGHVTAYSMADGKVLWR 213
Cdd:COG1520   201 NGQPLWEQRVAQP-RGRTelerlVDVDGTPV-------VDGGVvYAVayQGRLAALDLRSGRVLWS 258
PQQ pfam01011
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ...
 504-535 1.16e-04

PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.


Pssm-ID: 395799 [Multi-domain]  Cd Length: 36  Bit Score: 39.48  E-value: 1.16e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1549734172 504 DVVFYGTLEGYLKAVDAATGKELYRFKTPSGV 535
Cdd:pfam01011   1 GTVYLGSDDGYLYALDAETGKVLWSFKTGGAV 32
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 78-213 1.91e-04

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 44.03  E-value: 1.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172  78 GSPLVIGDLMYVHTpFPNTVYALDLSkDGQIVWKYEpkqdpnvipvmccDTVNRGVAYADNKIFLHQADTTVVALDAKTG 157
Cdd:COG1520   227 GTPVVDGGVVYAVA-YQGRLAALDLR-SGRVLWSRD-------------LSSYTGLAVDGNNLYVTDDDGRVWALDRRNG 291

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1549734172 158 KVIWsvKNgDATKGETNTATVmPVKDKILVGisggefGVRGHVTAYSMADGKVLWR 213
Cdd:COG1520   292 AELW--KQ-DALLYRGLTAPV-VLGDYVVVG------DFEGYLHWLSRDDGSLVAR 337
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 145-213 2.69e-04

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 42.78  E-value: 2.69e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1549734172 145 ADTTVVALDAKTGKVIWSVKNGDATKGEtntatvMPVKDKILVGISGGefgvrGHVTAYSMADGKVLWR 213
Cdd:pfam13360   1 ADGVVTALDAATGAELWRVDLETGLGGG------VAVDGGRLFVATGG-----GQLVALDAATGKLLWR 58
BamB_YfgL cd10276
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ...
 472-550 2.84e-04

Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.


Pssm-ID: 199834 [Multi-domain]  Cd Length: 358  Bit Score: 43.47  E-value: 2.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 472 GNFIAWDNKEGKIKWS--LPEPfSVWSGALATAGDVVFYGTLEGYLKAVDAATGKELYRFKTPSGVIGNVMTYArEGKQY 549
Cdd:cd10276    48 GQVSAFNATTGKIIWEtsLSGK-GFLGGTPAVGNGKIFVGTESGYLYALDAKDGSELWRTEVSDSQLLSPPTYA-DGKIY 125


                  .
gi 1549734172 550 V 550
Cdd:cd10276   126 V 126
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 472-536 5.86e-04

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 42.49  E-value: 5.86e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1549734172 472 GNFIAWDNKEGKIKWS--LPEPFSvwsGALATAGDVVFYGTLEGYLKAVDAATGKELYRFKTPSGVI 536
Cdd:COG1520    67 GRVAALDAATGKELWRvdLGEPLS---GGVGADGGLVVVGTEDGEVIALDADDGEELWRARLSSEVL 130
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 470-558 7.65e-04

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 41.23  E-value: 7.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 470 GMGNFIAWDNKEGKIKWSLpEPFSVWSGALATAGDVVFYGTLEGYLKAVDAATGKELYRFKTPSGVIGNV-----MTYAR 544
Cdd:pfam13360   1 ADGVVTALDAATGAELWRV-DLETGLGGGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAPlvaggRVFVV 79

                          90
                  ....*....|....
gi 1549734172 545 EGKQYVAVLSGVGG 558
Cdd:pfam13360  80 AGDGSLIALDAADG 93
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 469-555 9.71e-03

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 38.15  E-value: 9.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1549734172 469 GGMGNFIAWDNKEGKIKWS--LPEPFSvwsGALATAGDVVFYGTLEGYLKAVDAATGKELYRFKTPSG---VIGNVMTYA 543
Cdd:pfam13360  40 TGGGQLVALDAATGKLLWRqtLSGEVL---GAPLVAGGRVFVVAGDGSLIALDAADGRRLWSYQRSGEplaLRSSGSPAV 116

                          90
                  ....*....|..
gi 1549734172 544 REGKQYVAVLSG 555
Cdd:pfam13360 117 VGDTVVAGFSSG 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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