|
Name |
Accession |
Description |
Interval |
E-value |
| PBP1_ABC_LIVBP-like |
cd06342 |
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ... |
27-358 |
1.83e-145 |
|
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.
Pssm-ID: 380565 [Multi-domain] Cd Length: 334 Bit Score: 415.00 E-value: 1.83e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVADGVKFVVGHFNSGVSIP 106
Cdd:cd06342 2 IGVAGPLTGPNAALGQDIRNGAELAVDEINAKGGGLGFKIELVAQDDACDPAQAVAAAQKLVADGVVAVIGHYNSGAAIA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 107 ASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSMNE 186
Cdd:cd06342 82 AAPIYAEAGIPMISPSATNPKLTEQGYKNFFRVVGTDDQQGPAAADYAAKTLKAKRVAVIHDGTAYGKGLADAFKKALKA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 187 AGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVDGT 266
Cdd:cd06342 162 LGGTVVGREGITPGTTDFSALLTKIKAANPDAVYFGGYYPEAGLLLRQLREAGLKAPFMGGDGIVSPDFIKAAGDAAEGV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 267 LMTFAPDP-RKSPAAKDLVEKFRAAGF-EPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKaKGPFKTAIGELGFDE 344
Cdd:cd06342 242 YATTPGAPpEKLPAAKAFLKAYKAKFGePPGAYAAYAYDAAQVLLAAIEKAGSTDRAAVAAALR-ATDFDGVTGTISFDA 320
|
330
....*....|....
gi 1550354570 345 KGDITRPDYVMYTW 358
Cdd:cd06342 321 KGDLTGPAFTVYQV 334
|
|
| PRK15404 |
PRK15404 |
high-affinity branched-chain amino acid ABC transporter substrate-binding protein; |
1-361 |
1.41e-136 |
|
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
Pssm-ID: 237959 [Multi-domain] Cd Length: 369 Bit Score: 394.00 E-value: 1.41e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 1 MKKSLLSAVALTAMVAFSGTAWAD-ILVGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQ 79
Cdd:PRK15404 1 MKSKGKTLLAGCIALALSHAALADdIKIAIVGPMSGPVAQYGDMEFTGARQAIEDINAKGGIKGDKLEGVEYDDACDPKQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 80 GVSVAQKFVADGVKFVVGHFNSGVSIPASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFK 159
Cdd:PRK15404 81 AVAVANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLIFRTIGLDSDQGPTAAKYILEKVK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 160 DAKVAVIHDKTPYGQGLADETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQG 239
Cdd:PRK15404 161 PKRIAVLHDKQQYGEGLARSVKDGLKKAGANVVFFEGITAGDKDFSALIAKLKKENVDFVYYGGYHPEMGQILRQAREAG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 240 LKATMMSGDGIVSNELASIAGDAVDGTLMTFAPDPRKSPAAKDLVEKFRAAGFEPE-AYTLYAYAALQVIAEGAKAAGNT 318
Cdd:PRK15404 241 LKTQFMGPEGVGNKSLSNIAGPASEGMLVTLPKRYDQDPANKAIVDAFKAKKQDPSgPFVWTTYAAVQSLAAGINRAGSD 320
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1550354570 319 DPQAVAEAIKAkGPFKTAIGELGFDEKGDITRPDYVMYTWKKG 361
Cdd:PRK15404 321 DPAKVAKYLKA-NTFDTVIGPLSWDEKGDLKGFEFGVFEWHAD 362
|
|
| PBP1_ABC_HAAT-like |
cd06349 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-366 |
6.57e-88 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380572 [Multi-domain] Cd Length: 338 Bit Score: 268.67 E-value: 6.57e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVAD-GVKFVVGHFNSGVSI 105
Cdd:cd06349 2 IGVSGPLTGDNAEYGQQFKNGVELAVDEINAAGGVNGRKLELVVYDDQGDPKEAVNIAQKFVSDdKVVAVIGDFSSSCSM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWnTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd06349 82 AAAPIYEEAGLVQISPTASHPDFTKGGDY-VFRNSPTQAVEAPFLADYAVKKLGAKKIAIIYLNTDWGVSAADAFKKAAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVDG 265
Cdd:cd06349 161 ALGGEIVATEAYLPGTKDFSAQITKIKNANPDAIYLAAYYNDAALIAKQARQLGWDVQIFGSSSLYSPEFIELAGDAAEG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 266 TLMT---FAPDPRksPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGnTDPQAVAEAIKAKGPFKTAIGELG 341
Cdd:cd06349 241 VYLSspfFPESPD--PEVKEFVKAYKAKyGEDPDDFAARAYDAVNILAEAIEKAG-TDREAIRDALANIKDFSGLTGTIT 317
|
330 340
....*....|....*....|....*
gi 1550354570 342 FDEKGDITRPdyvmYTWKKGDDGKF 366
Cdd:cd06349 318 FDENGDVLKS----LTILVVKDGKF 338
|
|
| LivK |
COG0683 |
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ... |
23-370 |
6.10e-87 |
|
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];
Pssm-ID: 440447 [Multi-domain] Cd Length: 314 Bit Score: 265.26 E-value: 6.10e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 23 ADILVGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNS 101
Cdd:COG0683 2 DPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAAGGVLGRKIELVVEDDASDPDTAVAAARKLIDqDKVDAIVGPLSS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 102 GVSIPASEIYAENGILQVTPASTNPQFTER-GLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADET 180
Cdd:COG0683 82 GVALAVAPVAEEAGVPLISPSATAPALTGPeCSPYVFRTAPSDAQQAEALADYLAKKLGAKKVALLYDDYAYGQGLAAAF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 181 KKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMmsgdgivsnelasiag 260
Cdd:COG0683 162 KAALKAAGGEVVGEEYYPPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKGPL---------------- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 261 davdgtlmtfapdprkspaAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKaKGPFKTAIGE 339
Cdd:COG0683 226 -------------------NKAFVKAYKAKyGREPSSYAAAGYDAALLLAEAIEKAGSTDREAVRDALE-GLKFDGVTGP 285
|
330 340 350
....*....|....*....|....*....|.
gi 1550354570 340 LGFDEKGDITRPdYVMYTWKKgdDGKFSYFQ 370
Cdd:COG0683 286 ITFDPDGQGVQP-VYIVQVKA--DGKFVVVE 313
|
|
| PBP1_ABC_LivK_ligand_binding-like |
cd06347 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-355 |
1.73e-83 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380570 [Multi-domain] Cd Length: 334 Bit Score: 257.09 E-value: 1.73e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd06347 2 IGVIGPLTGEAAAYGQPALNGAELAVDEINAAGGILGKKIELIVYDNKSDPTEAANAAQKLIDeDKVVAIIGPVTSSIAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWNtFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKT-PYGQGLADETKKSM 184
Cdd:cd06347 82 AAAPIAQKAKIPMITPSATNPLVTKGGDYI-FRACFTDPFQGAALAKFAYEELGAKKAAVLYDVSsDYSKGLAKAFKEAF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 185 NEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVD 264
Cdd:cd06347 161 EKLGGEIVAEETYTSGDTDFSAQLTKIKAANPDVIFLPGYYEEAALIIKQARELGITAPILGGDGWDSPELLELGGDAVE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 265 GTLMT--FAPDPrKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKAKGPFKTAIGELG 341
Cdd:cd06347 241 GVYFTthFSPDD-PSPEVQEFVKAYKAKyGEPPNAFAALGYDAVMLLADAIKRAGSTDPEAIRDALAKTKDFEGVTGTIT 319
|
330
....*....|....
gi 1550354570 342 FDEKGDITRPDYVM 355
Cdd:cd06347 320 FDPNGNPIKPAVIL 333
|
|
| PBP1_ABC_transporter_LIVBP-like |
cd06268 |
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ... |
27-309 |
5.89e-76 |
|
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.
Pssm-ID: 380492 [Multi-domain] Cd Length: 298 Bit Score: 236.84 E-value: 5.89e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd06268 2 IGVVVPLTGPYADYGEEILRGVALAVEEINAAGGINGRKLELVIADDQGDPETAVAVARKLVDdDKVLAVVGHYSSSVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd06268 82 AAAPIYQEAGIPLISPGSTAPELTEGGGPYVFRTVPSDAMQAAALADYLAKKLKGKKVAILYDDYDYGKSLADAFKKALK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVDG 265
Cdd:cd06268 162 ALGGEIVAEEDFPLGTTDFSAQLTKIKAAGPDVLFLAGYGADAANALKQARELGLKLPILGGDGLYSPELLKLGGEAAEG 241
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1550354570 266 TLMT--FAPDPRKSPAAKDLVEKFRAAGFEPEAYTLYAYAALQVIA 309
Cdd:cd06268 242 VVVAvpWHPDSPDPPKQAFVKAYKKKYGGPPSWRAATAYDATQALA 287
|
|
| PBP1_ABC_HAAT-like |
cd06344 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
24-356 |
1.27e-72 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380567 [Multi-domain] Cd Length: 332 Bit Score: 229.42 E-value: 1.27e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 24 DILVGVGGPLtgpnAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVAD-GVKFVVGHFNSG 102
Cdd:cd06344 1 DIVIGVAWPF----APDGDLFLEGVELAVEEINAAGGVLGRKIRLVEYDDEASVDKGLAIAQRFADNpDVVAVIGHRSSY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 103 VSIPASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAAN-FKdaKVAVIHDKTPYGQGLADETK 181
Cdd:cd06344 77 VAIPASIIYERAGLLMLSPGATAPKLTQHGFKYIFRNIPSDEDIARQLARYAARQgYK--RIVIYYDDDSYGKGLANAFE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 182 KSMNEAGVTEALYEGINTGDKDFSALIAKMKQAG-VSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAG 260
Cdd:cd06344 155 EEARELGITIVDRRSYSSDEEDFRRLLSKWKALDfFDAIFLAGSMPEGAEFIKQARELGIKVPIIGGDGLDSPELIEIAG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 261 DAVDGT-LMTFAPDPRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKAKGPFKTAIG 338
Cdd:cd06344 235 KAAEGVvVATVFDPDDPRPEVRAFVEAFRKKyGREPDVWAAQGYDAVKLLAEAIEKAGSTVPAKIASALRFLENWEGVTG 314
|
330
....*....|....*...
gi 1550354570 339 ELGFDEKGDITRPDYVMY 356
Cdd:cd06344 315 TYSFDANGDVVGKAIYFK 332
|
|
| PBP1_ABC_ligand_binding-like |
cd19980 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-355 |
5.18e-71 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380635 [Multi-domain] Cd Length: 334 Bit Score: 225.18 E-value: 5.18e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd19980 2 IGVIAPLSGPVAALGQQVLNGAKLAVEEINAKGGVLGRKLELVVEDDKCPPAEGVAAAKKLITdDKVPAIIGAWCSSVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd19980 82 AVMPVAERAKVPLVVEISSAPKITEGGNPYVFRLNPTNSMLAKAFAKYLADKGKPKKVAFLAENDDYGRGAAEAFKKALK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVDG 265
Cdd:cd19980 162 AKGVKVVATEYFDQGQTDFTTQLTKLKAANPDAIFVVAETEDGALILKQARELGLKQQLVGTGGTTSPDLIKLAGDAAEG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 266 TLMTFAPDP-RKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKAKGPFKTAIGELGFD 343
Cdd:cd19980 242 VYGASIYAPtADNPANKAFVAAYKKKyGEPPDKFAALGYDAVMVIAEAIKKAGSTDPEKIRAAALKKVDYKGPGGTIKFD 321
|
330
....*....|..
gi 1550354570 344 EKGDITRPDYVM 355
Cdd:cd19980 322 EKGQAHKNVVLV 333
|
|
| PBP1_ABC_ligand_binding-like |
cd06340 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
27-358 |
4.12e-70 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380563 [Multi-domain] Cd Length: 352 Bit Score: 223.59 E-value: 4.12e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGI---NGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSG 102
Cdd:cd06340 2 IGVLYPLSGPLALIGQEAKRGAELAVDEINAAGGIkslGGAKIELVVADTQSDPEVAASEAERLITqEGVVAIIGAYSSS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 103 VSIPASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYI-----AANFKDAKVAVIHDKTPYGQGLA 177
Cdd:cd06340 82 VTLAASQVAERYGVPFVTASAVADEITERGFKYVFRTAPTASQFAEDAVDFLkelakKKGKKIKKVAIIYEDSAFGTSVA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 178 DETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGL--KATMMSGDGIVSNEL 255
Cdd:cd06340 162 KGLKKAAKKAGLEVVLDEPYPAGATDLSSEVLKLKAAKPDVVFATSYTNDAILLLRTMKELGFkpKAIIGVGGGYSDPEF 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 256 ASIAGDAVDGTLMT--FAPD-PRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAV--AEAIKA 329
Cdd:cd06340 242 LKALGKDAEGVFSVvpWSPDlAKKKPGAKEVNERYKKKyGEDMTGHAARAYTAAWVLADALERAGSTDPEAIraAAALTL 321
|
330 340 350
....*....|....*....|....*....|.
gi 1550354570 330 KGPFKTAI--GELGFDEKGDITRPDYVMYTW 358
Cdd:cd06340 322 DIPEGLIMpgGGVKFDEKGQNVLARPVVVQW 352
|
|
| PBP1_ABC_ligand_binding-like |
cd19984 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-309 |
2.41e-68 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380639 [Multi-domain] Cd Length: 296 Bit Score: 217.09 E-value: 2.41e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd19984 2 IGVILPLTGDAASYGEDMKNGIELAVEEINAAGGINGKKIELIYEDSKCDPKKAVSAANKLINvDKVKAIIGGVCSSETL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWnTFRTCGRDDQQGAVAGAYIAANFKDaKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd19984 82 AIAPIAEQNKVVLISPGASSPEITKAGDY-IFRNYPSDAYQGKVLAEFAYNKLYK-KVAILYENNDYGVGLKDVFKKEFE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVDG 265
Cdd:cd19984 160 ELGGKIVASESFEQGETDFRTQLTKIKAANPDAIFLPGYPKEGGLILKQAKELGIKAPILGSDGFEDPELLEIAGEAAEG 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1550354570 266 TLMTF-APDPRKSPAAKDLVEKFRA-AGFEPEAYTLYAYAALQVIA 309
Cdd:cd19984 240 VIFTYpAFDDSSEKKQKFFFYRYKEkYGKEPDIYAALAYDAVMILA 285
|
|
| PBP1_ABC_HAAT-like |
cd19988 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-309 |
1.67e-67 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380643 [Multi-domain] Cd Length: 302 Bit Score: 215.22 E-value: 1.67e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd19988 2 IGVFGPLSGDAAPYGQAMLQGAELAVEEINAAGGILGIPIELVVEDDEGLPAASVSAAKKLIYqDKVWAIIGSINSSCTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd19988 82 AAIRVALKAGVPQINPGSSAPTITESGNPWVFRCTPDDRQQAYALVDYAFEKLKVTKIAVLYVNDDYGRGGIDAFKDAAK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVDG 265
Cdd:cd19988 162 KYGIEVVVEESYNRGDKDFSPQLEKIKDSGAQAIVMWGQYTEGALIAKQARELGLKQPLFGSDGLVTPKFIELAGDAAEG 241
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1550354570 266 TLMTFAPDPRK-SPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIA 309
Cdd:cd19988 242 AIATTPFLPDSdDPKVSAFVEKYKKRyGEEPDVFAAQAYDAMNILA 287
|
|
| PBP1_ABC_ligand_binding-like |
cd06335 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
27-361 |
2.54e-67 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380558 [Multi-domain] Cd Length: 348 Bit Score: 215.94 E-value: 2.54e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFV-ADGVKFVVGHFNSGVSI 105
Cdd:cd06335 2 IGVIGPLTGPSAELGESARRGVELAVEEINAAGGILGRKIELVERDDEANPTKAVQNAQELIdKEKVVAIIGPTNSGVAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFT---ERGLWNTFRTCGRDDQQGAVAGAYIAANFKDaKVAVIHDKTPYGQGLADETKK 182
Cdd:cd06335 82 ATIPILQEAKIPLIIPVATGTAITkppAKPRNYIFRVAASDTLQADFLVDYAVKKGFK-KIAILHDTTGYGQGGLKDVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 183 SMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDA 262
Cdd:cd06335 161 ALKKRGITPVATESFKIGDTDMTPQLLKAKDAGADVILVYGLGPDLAQILKAMEKLGWKVPLVGSWGLSMPNFIELAGPL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 263 VDGTLM--TFAPDPRkSPAAKDLVEKFRAAGFEPEAYTLY----AYAALQVIAEGAKAAGNTDPQAVAEAI-KAKGPF-- 333
Cdd:cd06335 241 AEGTIMtqTFIEDYL-TPRAKKFIDAYKKKYGTDRIPSPVsaaqGYDAVYLLAAAIKQAGSTDGKKIRAALeNLKGYVgg 319
|
330 340
....*....|....*....|....*....
gi 1550354570 334 -KTAIGELGFDEKGDITRPDYVMYTWKKG 361
Cdd:cd06335 320 vKTYNKPFSKTDHEALDVSMVVLGYWKDG 348
|
|
| PBP1_ABC_ligand_binding-like |
cd06346 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-357 |
6.45e-60 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380569 [Multi-domain] Cd Length: 314 Bit Score: 195.86 E-value: 6.45e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd06346 2 IGALLPLTGPLASLGPPMLAAAELAVEEINAAGGVLGKKVELVVEDSQTDPTAAVDAARKLVDvEGVPAIVGAASSGVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTE---RGLWntFRTCGRDDQQGAVAgAYIAANFKDAKVAVIHDKTPYGQGLADETKK 182
Cdd:cd06346 82 AVASVAVPNGVVQISPSSTSPALTTledKGYV--FRTAPSDALQGVVL-AQLAAERGFKKVAVIYVNNDYGQGLADAFKK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 183 SMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKAT-MMSGDGIVSNEL-ASIAG 260
Cdd:cd06346 159 AFEALGGTVTASVPYEPGQTSYRAELAQAAAGGPDALVLIGYPEDGATILREALELGLDFTpWIGTDGLKSDDLvEAAGA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 261 DAVDGTLMTfAPDPRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIA---EGakAAGNTDpqavaeaikakgpfkta 336
Cdd:cd06346 239 EALEGMLGT-APGSPGSPAYEAFAAAYKAEyGDDPGPFAANAYDAVMLLAlayEG--ASGPID----------------- 298
|
330 340
....*....|....*....|.
gi 1550354570 337 igelgFDEKGDITrPDYVMYT 357
Cdd:cd06346 299 -----FDENGDVA-GPYEIWK 313
|
|
| PBP1_ABC_ligand_binding-like |
cd06338 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
32-361 |
6.76e-59 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380561 [Multi-domain] Cd Length: 347 Bit Score: 194.34 E-value: 6.76e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 32 PLTGPNAAFGAQLQKGAEQAAEDINAAGGINGE----QIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSIP 106
Cdd:cd06338 7 SLTGPFAGEGKAQKRGYELWVEDVNAAGGVKGGgkkrPVELVYYDDQSDPATAVRLYEKLITeDKVDLLLGPYSSGLTLA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 107 ASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAAN-FKDAKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd06338 87 AAPVAEKYGIPMIAGGAASDSIFERGYKYVFGVLPPASDYAKGLLDLLAELgPKPKTVAIVYEDDPFGKEVAEGAREAAK 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSN-ELASIAGDAVD 264
Cdd:cd06338 167 KAGLEVVYDESYPPGTTDFSPLLTKVKAANPDILLVGGYPPDAITLVRQMKELGYNPKAFFLTVGPAFpAFREALGKDAE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 265 GTL--MTFAPDPRKS--PAAKDLVEKFRA-AGFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIkAKGPFKTAIGE 339
Cdd:cd06338 247 GVLgpSQWEPSLPYKvfPGAKEFVKAYKEkFGEEPSYHAAAAYAAGQVLQQAIEKAGSLDPEKVRDAL-ASLDFDTVYGP 325
|
330 340
....*....|....*....|..
gi 1550354570 340 LGFDEKGDITRPDYVMYTWKKG 361
Cdd:cd06338 326 IKFDETGLQIGKPMVVVQWQGG 347
|
|
| PBP1_ABC_HAAT-like |
cd19986 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-309 |
4.59e-56 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380641 [Multi-domain] Cd Length: 297 Bit Score: 185.52 E-value: 4.59e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 26 LVGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVADG-VKFVVGHFNSGVS 104
Cdd:cd19986 1 KIGVVAPLTGPAALNGEYQKNGAQLALEEINAAGGVLGRPLELVVEDDQGTNTGAVNAVNKLISDDkVVAVIGPHYSTQV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 105 IPASEIYAENGILQVTpASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSM 184
Cdd:cd19986 81 LAVSPLVKEAKIPVIT-GGTSPKLTEQGNPYMFRIRPSDSVSAKALAKYAVEELGAKKIAILYDNDDFGTGGADVVTAAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 185 NEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVD 264
Cdd:cd19986 160 KALGLEPVAVESYNTGDKDFTAQLLKLKNSGADVIIAWGHDAEAALIARQIRQLGLDVPVIGSSSFATPTVLLLAGEALE 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1550354570 265 GT--LMTFAPDPrKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIA 309
Cdd:cd19986 240 GIysVTDFVPSD-PDPKVQAFVKKYKAKyGEDPDLYSAWYYDAMYLLA 286
|
|
| PBP1_ABC_RPA1789-like |
cd06333 |
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ... |
27-327 |
1.35e-55 |
|
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380556 [Multi-domain] Cd Length: 342 Bit Score: 185.44 E-value: 1.35e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd06333 2 IGAILSLTGPAASLGIPERNAVELLVEQINAAGGINGRKLELIVYDDESDPTKAVTNARKLIEeDKVDAIIGPSTTGESL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWnTFRTCGRDDQQGAVAGAYIAANfKDAKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd06333 82 AVAPIAEEAKVPLISLAGAAAIVEPVRKW-VFKTPQSDSLVAEAILDYMKKK-GIKKVALLGDSDAYGQSGRAALKKLAP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVDG 265
Cdd:cd06333 160 EYGIEIVADERFARTDTDMTAQLTKIRAAKPDAVLVWASGPPAALVAKNLRQLGYKGPIYQSHGAANQDFIKLAGKAAEG 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1550354570 266 TLMTFAP----------DPRKsPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAI 327
Cdd:cd06333 240 VILPAGKllvadqlpdsDPQK-KVLLEFVKAYEAKyGEGPSTFAGHAYDALLLLVEAIEPAGGTDRAALRDAL 311
|
|
| Peripla_BP_6 |
pfam13458 |
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ... |
25-363 |
4.39e-55 |
|
Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.
Pssm-ID: 433225 [Multi-domain] Cd Length: 342 Bit Score: 184.40 E-value: 4.39e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 25 ILVGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGV 103
Cdd:pfam13458 2 IKIGVLTPLSGPYASSGKSSRAGARAAIEEINAAGGVNGRKIELVVADDQGDPDVAAAAARRLVDqDGVDAIVGGVSSAV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 104 SIPASEIYAENGILQVTPASTNPQFTERglwNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKS 183
Cdd:pfam13458 82 ALAVAEVLAKKGVPVIGPAALTGEKCSP---YVFSLGPTYSAQATALGRYLAKELGGKKVALIGADYAFGRALAAAAKAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 184 MNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVS--NELASIAGD 261
Cdd:pfam13458 159 AKAAGGEVVGEVRYPLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDAKGIKLVGLGGdePDLKALGGD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 262 AVDGTLMT--FAPDPRkSPAAKDLVEKFRAA--GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKAkGPFKTAI 337
Cdd:pfam13458 239 AAEGVYATvpFFPDLD-NPATRAFVAAFAAKygEAPPTQFAAGGYIAADLLLAALEAAGSPTREAVIAALRA-LPYDGPF 316
|
330 340
....*....|....*....|....*.
gi 1550354570 338 GELGFDEKGDITRPDYVMYTWKKGDD 363
Cdd:pfam13458 317 GPVGFRAEDHQAVHCMYLVQVKADGK 342
|
|
| PBP1_ABC_ligand_binding-like |
cd06345 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-358 |
1.03e-53 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380568 [Multi-domain] Cd Length: 356 Bit Score: 180.92 E-value: 1.03e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTgpnAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd06345 2 IGVLGPLS---APAGEAMERGAELAVEEINAAGGILGRKVELVVADTQGKPEDGVAAAERLITeDKVDAIVGGFRSEVVL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWN------TFRTCGRDDQQGAVAGAYIAANFKDA----KVAVIHDKTPYGQG 175
Cdd:cd06345 79 AAMEVAAEYKVPFIVTGAASPAITKKVKKDyekykyVFRVGPNNSYLGATVAEFLKDLLVEKlgfkKVAILAEDAAWGRG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 176 LADETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNEL 255
Cdd:cd06345 159 IAEALKKLLPEAGLEVVGVERFPTGTTDFTPILSKIKASGADVIVTIFSGPGGILLVKQWAELGVPAPLVGINVPAQDPE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 256 A-SIAGDAVDGTLM--TFAPDPRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKaKG 331
Cdd:cd06345 239 FwENTGGAGEYEITlaFAAPKAKVTPKTKPFVDAYKKKyGEAPNYTAYTAYDAIYILAEAIERAGSTDPDALVKALE-KT 317
|
330 340 350
....*....|....*....|....*....|..
gi 1550354570 332 PFKTAIGELGFDEKGDIT-----RPDYVMYTW 358
Cdd:cd06345 318 DYEGVRGRIKFDKKDEYPhdvkyGPGYVTGLI 349
|
|
| PBP1_ABC_HAAT-like |
cd06348 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-355 |
2.08e-53 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380571 [Multi-domain] Cd Length: 342 Bit Score: 179.74 E-value: 2.08e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd06348 2 IGVALSLTGPGALYGQSQKNGAQLAVEEINAAGGVGGVKIELIVEDTAGDPEQAINAFQKLINqDKVLAILGPTLSSEAF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWnTFRTCGRDDQqgaVAGAYIAANFKDA---KVAVIhdktpYGQglADETKK 182
Cdd:cd06348 82 AADPIAQQAKVPVVGISNTAPGITDIGPY-IFRNSLPEDK---VIPPTVKAAKKKYgikKVAVL-----YDQ--DDAFTV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 183 S--------MNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNE 254
Cdd:cd06348 151 SgtkvfpaaLKKNGVEVLDTETFQTGDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPD 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 255 LASIAGDAVDGTLMTFAPDP-RKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAG-NTDPQAVAEA---IK 328
Cdd:cd06348 231 LIKLAGKAAEGVIVGSAWSPdNPDPKNQAFVAAYKEKyGKEPDQFAAQAYDAAYILAEAIKKAGsTTDRADLRDAlarIL 310
|
330 340
....*....|....*....|....*..
gi 1550354570 329 AKGPFKTAIGELGFDEKGDITRPDYVM 355
Cdd:cd06348 311 IAKDFEGPLGPFSFDADRDGIQPPVVL 337
|
|
| PBP1_ABC_ligand_binding-like |
cd06343 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
25-316 |
7.85e-52 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.
Pssm-ID: 380566 [Multi-domain] Cd Length: 355 Bit Score: 176.22 E-value: 7.85e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 25 ILVGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFV-ADGVKFVVGHFNSGV 103
Cdd:cd06343 7 IKIGTSLPLSGPAAAYGKPVRAGAAAYFDEVNAAGGINGRKIELIVEDDGYDPARAVAAVRKLVeQDKVFAIVGGLGTPT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 104 SIPASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKS 183
Cdd:cd06343 87 NLAVRPYLNEAGVPQLFPATGASALSPPPKPYTFGVQPSYEDEGRILADYIVETLPAAKVAVLYQNDDFGKDGLEGLKEA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 184 MNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVS-NELASIAGDA 262
Cdd:cd06343 167 LKAYGLEVVAEETYEPGDTDFSSQVLKLKAAGADVVVLGTLPKEAAAALKEAAKLGWKPTFLGSSVSADpTTLAKAGGDA 246
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 1550354570 263 VDGTLMT-FAPDP--RKSPAAKDLVEKFRAA--GFEPEAYTLYAYAALQVIAEGAKAAG 316
Cdd:cd06343 247 AEGVYSAsYLKDPtdADDPAVKEFREAYKKYfpDDPPNAYALYGYAAAQVFVEALKRAG 305
|
|
| PBP1_ABC_ligand_binding-like |
cd19982 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
27-309 |
9.48e-52 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380637 [Multi-domain] Cd Length: 302 Bit Score: 174.39 E-value: 9.48e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd19982 2 IGAILSLTGPFAPFGEMFKNGYEMALEEINAAGGIKGKKLELVIEDDQSKPQTALAAAEKLVSqDKVPLIVGGYSSGITL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd19982 82 PVAAVAERQKIPLLVPTAADDDITKPGYKYVFRLNPPASIYAKALFDFFKELVKPKTIAILYENTAFGTSVAKAARRFAK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGD--GIVSNELASIAGDAV 263
Cdd:cd19982 162 KRGIEVVADESYDKGATDFKPLLNKVKAANPDVVYMVSYLNDAILLMRQAKELGLNPKLFAGGgaGFTIPEFLKQAGPLA 241
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1550354570 264 DGTLMT--FAPDPrKSPAAKDLVEKFRA-AGFEPEAYTLYAYAALQVIA 309
Cdd:cd19982 242 EYVVTAtlWSPDV-KYPGAKEFYEKYKAkYGVEPSYHEAEAYAALYVAA 289
|
|
| PBP1_ABC_HAAT-like |
cd19981 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-309 |
3.79e-50 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380636 [Multi-domain] Cd Length: 297 Bit Score: 170.16 E-value: 3.79e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFV-ADGVKFVVGHFNSGVSI 105
Cdd:cd19981 2 IGFFAPLTGPAAADGKSALHGAELAVEQINAAGGINGKKVELVVYDDQASPKQAVNIAQKLIeQDKVVAVVSGSYSGPTR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWnTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd19981 82 AAAPIFQEAKVPMVSAYAVHPDITKAGDY-VFRVAFLGPVQGRAGAEYAVKDLGAKKVAILTIDNDFGKSLAAGFKEEAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAG---VTEALYEginTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDA 262
Cdd:cd19981 161 KLGaeiVSEYAYA---LGDRDFRPILTKIKSANPDAIYASGYYAEAAPIVKQARELGIKVPIIGQEGYDSPKFIEIAGSA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1550354570 263 VDGTLMTFAPD-PRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIA 309
Cdd:cd19981 238 AEGVIITTSLNrDSDRPITQKFIKEYRKRyGIDPDMVAASTYDAVMVLA 286
|
|
| PBP1_As_SBP-like |
cd06330 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
27-346 |
4.18e-49 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.
Pssm-ID: 380553 [Multi-domain] Cd Length: 342 Bit Score: 168.51 E-value: 4.18e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd06330 2 IGVITPLSGAAAVYGEPARNGAELAVEEINAAGGILGRKIELVVRDDKGKPDEAVRAARELVLqEGVDFLIGTISSGVAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLW-NTFRTCGRDDQQGAVAGAYIAANFKDAK-VAVIHDKTPYGQGLADETKKS 183
Cdd:cd06330 82 AVAPVAEELKVLFIATDAATDRLTEENFNpYVFRTSPNTYMDAVAAALYAAKKPPDVKrWAGIGPDYEYGRDSWAAFKAA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 184 MNEAG----VTEALYEGINTGdkDFSALIAKMKQAGVSIVY---YGGlhteaGLI--MRQMKDQGL--KATMMSGDGIVS 252
Cdd:cd06330 162 LKKLKpdveVVGELWPKLGAT--DYTAYITALLAAKPDGVFsslWGG-----DLVtfVKQAKPYGLfdKTKVVSGLGGGS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 253 NELASIAGDAVDGTLMT-----FAPDprkSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEA 326
Cdd:cd06330 235 EVLQALGKEMPEGLIGGgrypfGWPD---TPLNKAFVEAYRAKyGEYPTYWAYEAYAAVMALKAAIEKAGSTDTDKVIAA 311
|
330 340
....*....|....*....|
gi 1550354570 327 IKAKGpFKTAIGELGFDEKG 346
Cdd:cd06330 312 LEGLT-FDTPGGKITIRAED 330
|
|
| PBP1_ABC_ligand_binding-like |
cd06336 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
27-343 |
6.00e-48 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380559 [Multi-domain] Cd Length: 345 Bit Score: 165.48 E-value: 6.00e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGI--NGE--QIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNS 101
Cdd:cd06336 2 IGFLGPLSGPAAAWGLPMLRGLELAADEINAAGGIkvGGKkyKVEVVSYDDKYTPAEAVAAARRLVSqDGVKFIFGPGGS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 102 GVSIPASEIYAENGILQVTPASTNPqFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETK 181
Cdd:cd06336 82 AIAAAVQPVTERNKVLLLTAAFSDP-ILGPDNPLLFRIPPTPYEYAPPFIKWLKKNGPIKTVALIAPNDATGKDWAAAFV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 182 KSMNEAG---VTEALYEginTGDKDFSALIAKMKQAGVSIVYYGGL-HTEAGLIMRQMKDQGLKATMMSGDGIVSNE-LA 256
Cdd:cd06336 161 AAWKAAGgevVAEEFYD---RGTTDFYPVLTKILALKPDALDLGGSsPGPAGLIIKQARELGFKGPFVSEGGAKADEiLK 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 257 SIAGDAVDGTLMTFA--PDPRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKAK-GP 332
Cdd:cd06336 238 EVGGEAAEGFIGVLPadDDPIASPGAKAFVERYKKKyGEPPNSESALFYDAAYILVKAMEKAGTVDDTKKIRAALAMlSP 317
|
330
....*....|.
gi 1550354570 333 FKTAIGELGFD 343
Cdd:cd06336 318 DETLFGKLKWG 328
|
|
| PBP1_ABC_HAAT-like |
cd19985 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
27-354 |
5.87e-46 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380640 [Multi-domain] Cd Length: 321 Bit Score: 159.75 E-value: 5.87e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVADGVKFVVGHFNSGVSIP 106
Cdd:cd19985 2 IAVVGPMSGKSASKGKSMLRGAELYIDQINAAGGINGKKVKLDVFDDQNDPDAARKAAQIIVSDKALAVIGHYYSSASIA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 107 ASEIYAENGILQVTPASTNPQFTErglWNT--FRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSM 184
Cdd:cd19985 82 AGKIYKKAGIPAITPSATADAVTR---DNPwyFRVIFNDSLQGRFLANYAKKVLKKDKVSIIYEEDSYGKSLASVFEATA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 185 NEAGVTEALYEGINTGDKDFSALIAKM----KQAG--VSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDgivsnelaSI 258
Cdd:cd19985 159 RALGLKVLKKWSFDTDSSQLDQNLDQIvdelKKAPdePGVIFLATHADEGAKLIKKLRDAGLKAPIIGPD--------SL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 259 AGDAvdgtlmtFAPDPRKSPAAKDlvekfraagfEPEAYT--LYAYAAL---------QVIAEGAKAAGNTDPQAVA--- 324
Cdd:cd19985 231 ASES-------FAQGFAEYPEEKE----------EPGYYTdgIYATSPFifdianekaQKFRDTYQKRYGEEPSWIAafa 293
|
330 340 350
....*....|....*....|....*....|.
gi 1550354570 325 -EAIKAkgpfktAIGELGFDEKGDITRPDYV 354
Cdd:cd19985 294 yDAAML------AIGNIYFDSNGDAVKPVAI 318
|
|
| PBP1_ABC_transporter_GPCR_C-like |
cd04509 |
Family C of G-protein coupled receptors and their close homologs, the type 1 ... |
30-269 |
6.41e-37 |
|
Family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems; This CD includes members of the family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems. The family C GPCR includes glutamate/glycine-gated ion channels such as the NMDA receptor, G-protein-coupled receptors, metabotropic glutamate, GABA-B, calcium sensing, pheromone receptors, and atrial natriuretic peptide-guanylate cyclase receptors. The glutamate receptors that form cation-selective ion channels, iGluR, can be classified into three different subgroups according to their binding-affinity for the agonists NMDA (N-methyl-D-asparate), AMPA (alpha-amino-3-dihydro-5-methyl-3-oxo-4-isoxazolepropionic acid), and kainate. L-glutamate is a major neurotransmitter in the brain of vertebrates and acts through either mGluRs or iGluRs. mGluRs subunits possess seven transmembrane segments and a large N-terminal extracellular domain. ABC-type leucine-isoleucine-valine binding protein (LIVBP) is a bacterial periplasmic binding protein that has homology with the amino-terminal domain of the glutamate-receptor ion channels (iGluRs). The extracellular regions of iGluRs are made of two PBP-like domains in tandem, a LIVBP-like domain that constitutes the N terminus (included in this model) followed by a domain related to lysine-arginine-ornithine-binding protein (LAOBP) that belongs to the type 2 periplasmic binding fold protein superfamily. The uncharacterized periplasmic components of various ABC-type transport systems are also included in this family.
Pssm-ID: 380490 Cd Length: 306 Bit Score: 135.51 E-value: 6.41e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 30 GGPLTGPNAAFGAQLQKGAEQAAEDINAAG-GINGEQIKVVLGDDVSDPKQGVSVAQKFVAD------------------ 90
Cdd:cd04509 15 GVPCGDIVAQYGIQRFEAMEQALDDINADPnLLPNNTLGIVIYDDCCDPKQALEQSNKFVNDliqkdtsdvrctngeppv 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 91 -----GVKFVVGHFNSGVSIPASEIYAENGILQVTPASTNPQFTERGLWNTF-RTCGRDDQQGAVAGAYIAAnFKDAKVA 164
Cdd:cd04509 95 fvkpeGIKGVIGHLCSSVTIPVSNILELFGIPQITYAATAPELSDDRGYQLFlRVVPLDSDQAPAMADIVKE-KVWQYVS 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 165 VIHDKTPYGQGLADETKKSMNEAGVTEALYEGI--NTGDKDFSALIAKMKQAGVS-IVYYGGLHTEAGLIMRQMKDQGL- 240
Cdd:cd04509 174 IVHDEGQYGEGGARAFQDGLKKGGLCIAFSDGItaGEKTKDFDRLVARLKKENNIrFVVYFGYHPEMGQILRAARRAGLv 253
|
250 260 270
....*....|....*....|....*....|.
gi 1550354570 241 -KATMMSGDGIVS-NELASIAGDAVDGTLMT 269
Cdd:cd04509 254 gKFQFMGSDGWANvSLSLNIAEESAEGLITI 284
|
|
| PBP1_SBP-like |
cd19989 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
27-309 |
2.25e-34 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380644 [Multi-domain] Cd Length: 299 Bit Score: 128.55 E-value: 2.25e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd19989 2 IGVLTPLSGPYAALGEEARRGAQLAVEEINAAGGILGRPVELVVEDTEGKPATAVQKARKLVEqDGVDFLTGAVSSAVAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTP-ASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDaKVAVIHDKTPYGQGLADETKKSM 184
Cdd:cd19989 82 AVAPKAAELKVPYLVTvAADDELTGENCNRYTFRVNTSDRMIARALAPWLAENGGK-KWYIVYADYAWGQSSAEAFKEAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 185 NEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGL--KATMMSGDGIVSNELASIAGDA 262
Cdd:cd19989 161 EELGGEVVGTLFAPLGTTDFSSYITQISDSGADGLLLALAGSDAVNFLKQAGQFGLgkKYKIVGGILSIEPLALPALGDA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1550354570 263 VDGTLMT----FAPDprkSPAAKDLVEKFRAAGFEPEAYTLY-AYAALQVIA 309
Cdd:cd19989 241 AEGVYGGvrypPTLD---TPANRAFVEAYEKEYGEAPDNFAGeAYEAMQALA 289
|
|
| PBP1_AmiC-like |
cd06331 |
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ... |
27-328 |
3.68e-32 |
|
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380554 [Multi-domain] Cd Length: 333 Bit Score: 123.48 E-value: 3.68e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFV-ADGVKFVVGHFNSGVSI 105
Cdd:cd06331 2 IGLLTPLSGPASVYGRAIANGAELAVEEINAAGGVLGRPVELVVEDDASDPATAVAAARRLIqQDKVDAIVGPITSATRN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWNTfrtcG-RDDQQGAVAGAYIAANFKdAKVAVIHDKTPYGQGLADETKKSM 184
Cdd:cd06331 82 AVAPVAERAKVPLLYPTFYEGGECSPYLFCF----GeVPNQQLDPLIPWLMEEYG-KKFYLIGSDYVWPRTMNDAARRVI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 185 NEAG---VTEALYEginTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATM-MSGDGIVSNELASIAG 260
Cdd:cd06331 157 EAHGgevVGEEYLP---LGTTDFSSVIEKIKASGADVVLSTLVGADAVTFLKQFAAAGLRRKVrIAALLFDENTLAGLGA 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1550354570 261 DAVDGTLMT---FAPDPRksPAAKDLVEKFRAAgFEPEAYTLY-----AYAALQVIAEGAKAAGNTDPQAVAEAIK 328
Cdd:cd06331 234 EAAEGIYSVlsyFQSLDT--PENKAFVAAYRKK-FGEDAPPITslseaAYEAVHLYAAAVEKAGSTDPEAVIAALP 306
|
|
| PBP1_SBP-like |
cd06329 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
32-327 |
5.59e-31 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380552 [Multi-domain] Cd Length: 343 Bit Score: 120.46 E-value: 5.59e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 32 PLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVADGVKFVVGHFNSGVS---IPAS 108
Cdd:cd06329 7 PLSGPFASVGEIYLKGLQFAIEEINAGGGLLGRKIELVPFDNKGSPQEALIQLKKAIDQGIRFVLQGNSSAVAgalIDAI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 109 EIYAE----NGILQVTPASTNPQFTER--GLWnTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKK 182
Cdd:cd06329 87 EKHNQrnpdKRVLFLNYGAEAPELTGAkcSFW-HFRFDANADMKMAALADYMKKDGSIKKVYLINQDYSFGRDVAAAAKK 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 183 SMNEAG-----VTEALYEGINTgdKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATM----MSGDGIVSN 253
Cdd:cd06329 166 NLKKKRpdieiVGEDLHPLGKV--KDFSPYIAKIKASGADTVITGNWGNDLTLLMKAARDSGLKAPFytyyADGPGAPAA 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1550354570 254 elasiAGDAVDGTL---MTFAPDPrKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAI 327
Cdd:cd06329 244 -----IGEAGVGRLvavAYWHPNP-KTPELEKFAEAFRAKyGRYPDFNIGRTYMGVEMLAAAIKKAGSTDPEKVAKAL 315
|
|
| PBP1_aromatic_compounds-like |
cd06332 |
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ... |
27-354 |
1.38e-30 |
|
type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.
Pssm-ID: 380555 [Multi-domain] Cd Length: 336 Bit Score: 119.24 E-value: 1.38e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINaaGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd06332 2 IGLLAPLTGPFAALGEDMVRGFELALEEVG--GEVAGRKVELVVEDDAGDPDTAVTKARKLVEqDKVDVLIGPLSGDEGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLW-NTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKSM 184
Cdd:cd06332 80 AVAPYAKEPGVPFINPVAGADDLTQRAKApNFFRTSFTGSQWSAPLGDYAYKELGYKKVATIGSDYAFGYEQAAGFKRGF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 185 NEAG--VTEALYEGINTgdKDFSALIAKMKQAGVsIVYYGGLHTEAGLIMRQMKDQGLKATM-MSGDGIVSNELASIA-G 260
Cdd:cd06332 160 EAAGgeVVQEIWVPLGT--TDFSPYIAQIPSADD-AVFAFLGGADAVRFLKQYREFGLKDKIpLIGGGTTVDESVLPAmG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 261 DAVDGTL--MTFAPDpRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAA-GNTDPQAVAEAIKAKGPFKTA 336
Cdd:cd06332 237 DAALGIIsaSHYAEG-LDNPENKKFVAAYKKKfGKLPSLYAAGGYDGAQAILEALEAVgGDVSDKQALAAALRKVKFDSP 315
|
330
....*....|....*...
gi 1550354570 337 IGELGFDEKGDITRPDYV 354
Cdd:cd06332 316 RGPFSFDENRNPVQNVYI 333
|
|
| PBP1_ABC_HAAT-like |
cd19983 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
26-309 |
8.96e-29 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380638 [Multi-domain] Cd Length: 303 Bit Score: 113.45 E-value: 8.96e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 26 LVGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVADGVKFVVGHFNSGVSI 105
Cdd:cd19983 1 RIGFVGGLTGRYSDLGVQGRNGAQLAVEEINAAGGINGRPVELIIRDDQQDPEAAKAADRELIAGGVVAIIGHMTSAMTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWnTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKT--PYGQGLADETKKS 183
Cdd:cd19983 81 AVLPVINEAKVLMISPTVSTPELSGKDDY-FFRVTPTTRESAQALARYAYNRGGLRRVAVIYDLSnrAYSESWLDNFRSE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 184 MNEAGVTEALYEGINTG-DKDFSALIAKMKQAGVSIVYY--GGLHTeaGLIMRQMKDQGLKATMMSGDGIVSNELASIAG 260
Cdd:cd19983 160 FEALGGRIVAEIPFSSGaDVDFSDLARRLLASKPDGLLLvaSAVDT--AMLAQQIRKLGSKIPLFSSAWAATEELLELGG 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1550354570 261 DAVDGTLM--TFAPDPRkSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIA 309
Cdd:cd19983 238 KAVEGMLFsqAYDRNSS-NPRYLAFKEAYEERfGREPSFAAAYAYEAAMVLA 288
|
|
| PBP1_ABC_ligand_binding-like |
cd06326 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
25-333 |
2.25e-28 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380549 [Multi-domain] Cd Length: 339 Bit Score: 113.02 E-value: 2.25e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 25 ILVGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGV 103
Cdd:cd06326 1 IVIGQSAPLSGPLAELGREYLAGAKAYFDQVNAAGGINGRKIRLVTLDDGYDPARTVENTRQLIEqDKVVALFGYVGTAN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 104 SIPASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQgavaGAYIAANFKD---AKVAVIHDKTPYGQGLADET 180
Cdd:cd06326 81 VEAVLPLLEEAGVPLVGPLTGADSLREPGNPYVFHVRASYADE----VEKIVRHLATlglKRIAVVYQDDPFGKEGLAAA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 181 KKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAG 260
Cdd:cd06326 157 EAALAARGLEPVATAAVARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFIKALRAAGGAAQFYGLSVVGAAALAKALG 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1550354570 261 DAVDGTLMTFA-PDPR--KSPAAKDLVEKFRAAGFEPEAY-TLYAYAALQVIAEGAKAAG-NTDPQAVAEAIKAKGPF 333
Cdd:cd06326 237 DAARGVVVSQVvPNPWstTLPLVREYQAAMKAAGPKEPSYaSLEGYIAARVLVEALRRAGrNPTRESLVAALESLGRL 314
|
|
| PBP1_alkylbenzenes-like |
cd06360 |
type 1 periplasmic binding component of active transport systems predicted be involved in ... |
27-363 |
1.22e-25 |
|
type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Pssm-ID: 380583 [Multi-domain] Cd Length: 357 Bit Score: 105.84 E-value: 1.22e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDI-NAAGginGEQIKVVLGDDVSDPKQGVSVAQKFV-ADGVKFVVGHFNSGVS 104
Cdd:cd06360 2 IGVLLPLTGPLAVNGEDVRDGFELYFDEIgNQVA---GRKIELIVEDDEGKPDVGLTKARKLVeRDKVHVLAGIVSSAVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 105 IPASEIYAENGI-LQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKS 183
Cdd:cd06360 79 YAVRDYVVEQKIpLVISNAGAAPLTQELASPYIFRTSFSNGQYDAPFGQYAYEKLGYRRIAVMASDYAAGHEQAGAFART 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 184 MNEAG--VTEALYEGINTgdKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKAT--MMSGDGIVSNELASIA 259
Cdd:cd06360 159 FKQAGgkVVQEIYPPLGT--ADFAPYLARIQQDAADAVWAFFAGADAIRFVKQYDEYGLKGKlpLVGIGGLVDDAILPEQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 260 GDAVDGTLMTFAPDPR-KSPAAKDLVEKFRA-AGFEPEAYTLYAYAALQVIAEGAKAA-GNT-DPQAVAEAIKaKGPFKT 335
Cdd:cd06360 237 GDAALGIVSYLHYSAAlDTPENKAFVQAYRKkYGRDPGLYAEGGYVAARAIAEALEAVkGNVeDKEAFLEALR-KVRFEA 315
|
330 340
....*....|....*....|....*...
gi 1550354570 336 AIGELGFDEKGDITRPDYVMYTWKKGDD 363
Cdd:cd06360 316 PRGPFRFDPYQQAVVTTYIRRVEKVDGK 343
|
|
| PBP1_RPA0668_benzoate-like |
cd20014 |
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ... |
27-344 |
1.92e-25 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380667 [Multi-domain] Cd Length: 346 Bit Score: 105.01 E-value: 1.92e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINaaGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd20014 2 IGLLLPYSGVYAALGEDIRNGFQLYLDEHG--GKLGGRPIELVKEDDEADPDVALQKARKLIEqDKVDVLVGPVSSGVAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGI-LQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKdAKVAVIHDKTPYGQGLADETKKSM 184
Cdd:cd20014 80 AIRDVVEQAKVpLIVANAGANALTRAACSPYIFRTSFSNWQLGYALGKYAAENVG-KTVVTIASDYAAGREVVAGFKEGF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 185 NEAG--VTEALYEGINTgDKDFSALIAKMKQAGVSIVY--YGGlhTEAGLIMRQMKDQGLKATM-MSGDGIVSNE-LASI 258
Cdd:cd20014 159 EAAGgkVVGEIWTPLGT-TTDFSPYLTQIAASGPDAVYafFAG--ADAVRFVKQYAEFGLKGKIpLYGPGFLTDEdVLPA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 259 AGDAVDG--TLMTFAPDpRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEG-AKAAGNTDPQAVAEAIKAKGPFK 334
Cdd:cd20014 236 LGEAAEGiiTVLHYAPT-LDNPANRAFVAAYQAKyGRLPDVYAVQGYDAAQVIDAAlEAVGGDTSDKDILAAALELGSID 314
|
330
....*....|
gi 1550354570 335 TAIGELGFDE 344
Cdd:cd20014 315 SPRGPFRFDP 324
|
|
| ANF_receptor |
pfam01094 |
Receptor family ligand binding region; This family includes extracellular ligand binding ... |
43-359 |
5.78e-25 |
|
Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
Pssm-ID: 460062 [Multi-domain] Cd Length: 347 Bit Score: 104.00 E-value: 5.78e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 43 QLQKGAEQAAEDINAAGGIN-GEQIKVVLGDDVSDPKQGVSVAQKFVADGVKFVVGHFNSGVSIPASEIYAENGILQVTP 121
Cdd:pfam01094 1 LVLLAVRLAVEDINADPGLLpGTKLEYIILDTCCDPSLALAAALDLLKGEVVAIIGPSCSSVASAVASLANEWKVPLISY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 122 ASTNPQFTERGLWNTF-RTCGRDDQQGAVAGAyIAANFKDAKVAVIHDKTPYGQGLADETKKSMNEAGVT---EALYEGI 197
Cdd:pfam01094 81 GSTSPALSDLNRYPTFlRTTPSDTSQADAIVD-ILKHFGWKRVALIYSDDDYGESGLQALEDALRERGIRvayKAVIPPA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 198 NTGDKDFSALIAKMKQAGVSIVyyggLHTEAGL---IMRQMKDQGL---------KATMMSGDGIVSNELAsiagDAVDG 265
Cdd:pfam01094 160 QDDDEIARKLLKEVKSRARVIV----VCCSSETarrLLKAARELGMmgegyvwiaTDGLTTSLVILNPSTL----EAAGG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 266 TLmTFAPDPRKSPAAKDLVEKFRAAGF--------EPEAYTLYAYAALQVIAEGAKAAGNTDP--------------QAV 323
Cdd:pfam01094 232 VL-GFRLHPPDSPEFSEFFWEKLSDEKelyenlggLPVSYGALAYDAVYLLAHALHNLLRDDKpgracgalgpwnggQKL 310
|
330 340 350
....*....|....*....|....*....|....*.
gi 1550354570 324 AEAIKaKGPFKTAIGELGFDEKGDITRPDYVMYTWK 359
Cdd:pfam01094 311 LRYLK-NVNFTGLTGNVQFDENGDRINPDYDILNLN 345
|
|
| PBP1_SBP-like |
cd19987 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
27-328 |
1.64e-23 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380642 [Multi-domain] Cd Length: 353 Bit Score: 100.10 E-value: 1.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAG------------GINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVK 93
Cdd:cd19987 2 IGLNVPLSGPYAPQGEDQRRGFELAVDHLNNGGglvdkdsrlsgdGILGKKVELVTADTETKADTAVDNAKRLIEqDGAV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 94 FVVGHFNSGVSIPASEIYAENGILQVTPASTNPQFT-ERGLWNTFRTCGRDDQQGAVAGAYIAANF-KDAKVAVIHDKTP 171
Cdd:cd19987 82 MITGGSSSAVAVAAQKLAQKEGVLYFAGLSHSNDTTgKDCHRYGFRECFNAHMSAKALAPYLVEKFgKDRKYFYLTADYT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 172 YGQGLADETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSI---VYYGGlhtEAGLIMRQMKDQGLKATMmsgD 248
Cdd:cd19987 162 WGHSTEQSMREYTEAHGWKTVGNPATPLGETDFSAALLNAADSGADVlvlVLFGR---DMVNALKQAKQFGLLKKM---D 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 249 GIVSNELASIA----GDAVDGTLMTFAPDPR---KSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDP 320
Cdd:cd19987 236 IVVPLLTAFMAesvgPEIMEGVLGTVNWHWSlpdDYSYAFGKAEAFEKEyGAYPSQAAASAYVQVLQYAAAVERAGSFDP 315
|
....*...
gi 1550354570 321 QAVAEAIK 328
Cdd:cd19987 316 PAVIRALE 323
|
|
| PBP1_SBP-like |
cd06328 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
27-326 |
3.19e-23 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380551 [Multi-domain] Cd Length: 336 Bit Score: 98.91 E-value: 3.19e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEdiNAAGG---INGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSG 102
Cdd:cd06328 2 IGVITSLTGPLAAYGKQTERGFELGLE--YATDGtmeVDGRKIEVIVKDDQGDPDTAKAAATELIGdDGVDILVGTVSSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 103 VSIPASEIYAENG-ILQVTPASTnPQFTERGlWN--TFRTcGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADE 179
Cdd:cd06328 80 VALALAPVAEQNKkILIVGPAAA-DSITGEN-WNkyTFRT-SRNSWQDAIAGAKALADPLGKSVAFLAQDYAFGQDGVAA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 180 TKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAG---VSIVYYGglhTEAGLIMRQMKDQGLKATMMSGDGIVSNELA 256
Cdd:cd06328 157 FKKALEAKGGKIVGEELVPVTTTDFTPYLQRILDAKpdvLFVAWAG---TGALTLWQQLADQGVLDDIKVVTGGPDIATL 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1550354570 257 SIAGDAVDGT--LMTFAPDPRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEG-AKAAGNTDPQAVAEA 326
Cdd:cd06328 234 AALGDALPGIegLTYYYYGLPKNPVNDWLVKAHKERyNAPPDLFTAGGFAAAQAVVRAlEKAGGDTDVEKLIAA 307
|
|
| PBP1_ABC_ligand_binding-like |
cd19979 |
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ... |
33-337 |
4.09e-21 |
|
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380634 [Multi-domain] Cd Length: 350 Bit Score: 93.06 E-value: 4.09e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 33 LTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVADG-VKFVVGHFNSGVSIPASEIY 111
Cdd:cd19979 8 LSGGSAASGEAIKRGIQLAIDEINAAGGLLGRKLELVAKDHRGNPARGVDNLREFAADPdVLAVFGGLHSPVLLAELDFI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 112 AENGILQVTPASTNPQFTERGL---WnTFRTCGRDDQQGAV-AGAYIAANFKdaKVAVIHDKTPYGQGLADETKKSMNEA 187
Cdd:cd19979 88 HELKIPYLVPWAAATPITRNGYspnY-IFRLSVDDSLAGPFlVEYALKKGCK--RPALLLENTGWGRSNLKAMTKALAKK 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 188 GVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSN---ELASIAGDAVD 264
Cdd:cd19979 165 GLQPVGVEWFNWGDTDAKPQLRALKAAGADAILLVANAPEGAAIVKALAALPERLPIISHWGITGGdfpELPREALSKID 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 265 GTLM--TFAPDPRKSPAAKDLVEKFRAAGFEPE--------AYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKAKGPFK 334
Cdd:cd19979 245 LRFIqtFSFFDANQSPRGKQVLARYKRRYPVEDpesdipapVGFAHAYDLTHLLALAIEQAGSTDRAAVRAALELLPPHE 324
|
...
gi 1550354570 335 TAI 337
Cdd:cd19979 325 GLI 327
|
|
| PBP1_ABC_ligand_binding-like |
cd06341 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
27-316 |
1.58e-20 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380564 [Multi-domain] Cd Length: 340 Bit Score: 91.21 E-value: 1.58e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVADGVKFVVGHFNSGVSIP 106
Cdd:cd06341 2 IGLIYPDTGPGAASFSAARAGAEARFGLANAAGGINGRKVEYVWCDDQSDPATNLQAARQLVEDEKVFALVGSSSAASGS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 107 ASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQgaVAGAYIAANfKDAKVAVIHDKTPYG-QGLADETKKSMN 185
Cdd:cd06341 82 ANDYLAQAGIPVVGGAGVSVWCFRNMFSNFFSLGGGGSTT--TYGQYAAAL-GGTKAAVVVTDIPAAsQQLAQQLAASLR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAGDAVDG 265
Cdd:cd06341 159 AAGVEVVGTAPYAAAAPDYTAVAQAAKAAGADAVVGVLDPDVAARVLKAARAQGLDLKVALSPSGYDPSVLAAYGAALAG 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1550354570 266 TL--MTFAPDPRKSPAAKDlvekFRAA--GFEPE------AYTLYAYAALQVIAEGAKAAG 316
Cdd:cd06341 239 VSvaSTFLPFEADTPAVKA----YRAAmaKYAPElqdplqQFALSGYIAADLFVRGLEAAG 295
|
|
| PBP1_ABC_ligand_binding-like |
cd06334 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
27-351 |
1.72e-19 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380557 [Multi-domain] Cd Length: 360 Bit Score: 88.45 E-value: 1.72e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHfNSGVSI 105
Cdd:cd06334 2 IGLLTDLTGPTADVGKPYAQGVRDYLNYVNEEGGINGVKIELEECDTGYKVPRAVACYKRLKAqDGVVAILGW-GTGDTE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILqVTPASTNPQFTERGL---WNtFRTCGRDDQQGAVAGAYIAANF----KDAKVAVIHDKTPYGQglad 178
Cdd:cd06334 81 ALAPRVAKDKIP-YISASYGRSLADDGKvfpYN-FFVGATYSSQARALLKYIAQEWggklKGPKVAFVYHDSPFGR---- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 179 ETKKSMNEA----GVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNE 254
Cdd:cd06334 155 EPIPALKAYakelGFEVVAEQVPSPGALDATAQWLRIRRAGPDYVIIQGTGGSVAVIIKDAKRLGLKTKFIGNIWGGDED 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 255 LASIAGDAVDGTL-MTFAPDPRKSPAAKDLVEKFRAAG--FEPEA----YTLYAYAALQVIAEGAKAAGNTDPQAVAEAI 327
Cdd:cd06334 235 LIKLAGDAAEGYVgVSPFAFGTDDPPGKEIVEEVAKKGkgDGPEEvgtvYYNRGWATAMLAVEAIRRADKAGGGTGLGNK 314
|
330 340
....*....|....*....|....
gi 1550354570 328 KAKGPFKtaigeLGFDEKGDITRP 351
Cdd:cd06334 315 LKAGLER-----LKDFDLGGLAPP 333
|
|
| PBP1_amide_urea_BP-like |
cd06356 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
33-333 |
9.06e-19 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the type 1 periplasmic-binding proteins that are predicted to have a function similar to that of an active transport system for short chain amides and/or urea in bacteria and Archaea, by sequence comparison and phylogenetic analysis.
Pssm-ID: 380579 [Multi-domain] Cd Length: 334 Bit Score: 86.20 E-value: 9.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 33 LTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSIPASEIY 111
Cdd:cd06356 8 LSGGLNIYGKPMVHAMKLAVEEINAAGGLLGRQIELVAYDTQSDMQKYTQYAQQLILrDKVDVVFGGITSASREAIRPIL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 112 AENGILQVTPAstnpqFTERGLW--NTFRTCGRDDQQGAVAGAYIAANFkDAKVAVIHDKTPYGQGLADETKKSMNEAGV 189
Cdd:cd06356 88 RRNKILYFYNT-----QYEGGVCdkNTFCTGSTPEQQVSPLIEWAIKKY-GKKVYIIAADYNFGQISADWVKKYAKKNGG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 190 TEALYEGINTGDKDFSALIAKMKQAGVSIVYY---GGLHTEaglIMRQMKDQGLKAT--MMSGDGIVSNE---LASIAGD 261
Cdd:cd06356 162 EVVGEEFFPLDVTDFGPTIQKIQAAKPDFVVSllvGGNHIS---FYRQWAAAGLKKKipIVSTVFGAGNEhkvLSPPELE 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1550354570 262 AVDGTLMTFAPDPrkSPAAKDLVEKFRAA-GFEPEAYTL--YAYAALQVIAEGAKAAGNTDPQAVAEAIKAKGPF 333
Cdd:cd06356 239 GMYVSYSYFEELD--TPANKAFVAKWRAKyGDEPYINQEavGVYNAVYLWAEAVEKAGSTEREAVIAALESGISF 311
|
|
| PBP1_ABC_ligand_binding-like |
cd19978 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
25-317 |
3.00e-18 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380633 [Multi-domain] Cd Length: 341 Bit Score: 84.55 E-value: 3.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 25 ILVGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFV-ADGVKFVVGHFNSGV 103
Cdd:cd19978 1 IRLGMSAALSGPAAELGNEMKRGIEAAFNEVNAQGGVNGRKIKLIALDDGYEPDRTVKNTKKLIeEDKVFALIGYVGTPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 104 SIPASEIYAENGILQVTPASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQGLADETKKS 183
Cdd:cd19978 81 ALAALPLANEKKIPLFGPFTGAEFLRTPFLPYVFNLRASYADETEALVDYLVKTLGPKRIAIFYQNDAFGLAGLEGAKKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 184 MNEAG---VTEALYEginTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIVSNELASIAG 260
Cdd:cd19978 161 LKKRGltpVAEGSYT---RNTLDVEEALAKILKAKPEAIILVGTYAPAAEFIRLARAAGLNPLFANVSFVGSEALALELG 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1550354570 261 DAVDGTLMTFA-PDPRKSPAakDLVEKFRAA------GFEPEAYTLYAYAALQVIAEGAKAAGN 317
Cdd:cd19978 238 DYGEGVIVSQVvPDPNDSSL--PIVKEYREAmkkygpNAPPDFVSLEGYLAARLLVEALKKAGP 299
|
|
| PBP1_SBP-like |
cd20378 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
27-327 |
4.04e-17 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380668 [Multi-domain] Cd Length: 357 Bit Score: 81.62 E-value: 4.04e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEdinAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSGVSI 105
Cdd:cd20378 2 LGGLVSMSGAFAAAGKLADRGMRLAVE---EYGGALGRPLKYITRDTEGKPGTGVRKVQEAIAqDGARFFIGGTLSSVAL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTPASTNPQFTERGLWNTFR------TCGRddqqgAVAGAYIAANFKDAKVAVIHDKTPYGQGLADE 179
Cdd:cd20378 79 AVSEEAEKAGGVYITSGGADEITGSRCNRSTFRwsvptyGAIR-----QTVRPVIKAMPKAKRWYTITPQYVFGESLLKN 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 180 TKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAG---VSIVYYGGLHTEAgliMRQMKDQGLKATMMS----GDGIvs 252
Cdd:cd20378 154 AKEVLKEKGIEHVGNSYHSLGEREFSGYLTKAMAARpdvLLILNFGSQAVDA---LRQAVSFGLKRKMKIlvawSSGL-- 228
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1550354570 253 NELASIAGDAVDGTLMTFAPDPR-KSPAAKDLVEKFRAAGFEPEAYTL-YAYAALQVIAEGAKAAGNTDPQAVAEAI 327
Cdd:cd20378 229 DQFQELGPDICEGVYFGAQYWHDvDTPANKALVKVYQAKFKETPSYALaAGYACTRMLLDAIDKAGSTDPAAVIKAL 305
|
|
| PBP1_Nba-like |
cd06359 |
type 1 periplasmic binding component of active transport systems predicted to be involved in ... |
27-343 |
1.15e-16 |
|
type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.
Pssm-ID: 380582 [Multi-domain] Cd Length: 333 Bit Score: 79.99 E-value: 1.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINaaGGINGEQIKVVLGDDVSDPKQGVSVAQKFV-ADGVKFVVGHFNSGVSI 105
Cdd:cd06359 2 IGFITTLSGPAAVLGQDMRDGFNLALEQLG--GKLGGLPVEVVVEDDQLKPDVAKQAAERLIeRDKVDFVTGIIFSNVML 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASEIYAENGILQVTP-ASTNPQFTERGLWNTFRTCGRDDQQGAVAGAYiaANFKDAK-VAVIHDKTPYGQGLADETKKS 183
Cdd:cd06359 80 AVVKPVVDSKVFYISAnAGPSDLAGKGCNPNFFVTSWQNDQLHEAAGKY--ANDKGYKrVYLLAPNYQAGKDALAGFKRT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 184 MnEAGVTEALYEGIntGDKDFSALIAKMKQAGVSIVYY---GGLhteaGL-IMRQMKDQGLKATM-MSGDGIVSNE-LAS 257
Cdd:cd06359 158 Y-KGEVVGEIYTPL--GQLDFSAELAQIRAAKPDAVFAfypGGM----GVnFVKQYAQAGLKKKIpLYTVGTLDDEdLLP 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 258 IAGDAVDGTLMT--FAPDpRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGN--TDPQAVAEAIKaKGP 332
Cdd:cd06359 231 AMGDAALGVLSVsqWSPD-LDNPENKRFVAAFRKKyGRPPSNYAAQGYDAALLIDAAVKAVGGdlSDKDALRAALR-KAD 308
|
330
....*....|.
gi 1550354570 333 FKTAIGELGFD 343
Cdd:cd06359 309 FKSVRGAFRFN 319
|
|
| PBP1_ABC_ligand_binding-like |
cd06337 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
27-343 |
1.33e-14 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380560 [Multi-domain] Cd Length: 354 Bit Score: 74.26 E-value: 1.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQ---IKVVLGDDVSDPKQGVSVAQKFV-ADGVKFVVGHFNSG 102
Cdd:cd06337 2 IGRVSPLTGPLAAFGEADPWVLEQIREAFADGGIKVGGKkypVEIVVRDSQSDPNRAGEAARDLIlRDKVDLMLASGTPD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 103 VSIPASEIYAENGilqVTPASTN----PQFTERG--LWNTFRTC-----GRDDqqgaVAGAYIAAnFKDA----KVAVIH 167
Cdd:cd06337 82 TVNPVADQCEANG---VPCISTDapwqAWFFGRGgdPAKGFKWTfhffwGLED----IAANFLGM-WDQVptnkVVGLLW 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 168 DKTPYGQGLADETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMS- 246
Cdd:cd06337 154 PNDPDGTAFADAFLGLPAAAGYTLVDPGRFPPGTDDFSSIINAFKKAGVEIVTGVMIPPDFATFWRQAAQQGFKPKVVTi 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 247 GDGIVSNELASIAGDAVDG--TLMTFAPD-PRKSP----AAKDLVEKFRAAGFEPEAYTL-YAYAALQVIAEGAKAAGNT 318
Cdd:cd06337 234 GKALLFPSAVAALGDLGDGlsTEVWWSPAhPFKSSltgqTAAELADAYEKATGKQWTQPLgYAHALFEVAVDALKRAGSP 313
|
330 340
....*....|....*....|....*
gi 1550354570 319 DPQAVAEAIKAKGPfKTAIGELGFD 343
Cdd:cd06337 314 DDEAVRAALADTDL-DTIVGPVDFT 337
|
|
| PBP1_YraM_LppC_lipoprotein-like |
cd06339 |
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ... |
27-350 |
4.10e-14 |
|
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).
Pssm-ID: 380562 [Multi-domain] Cd Length: 331 Bit Score: 72.30 E-value: 4.10e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDinaaggINGEQIKVVLGDDvSDPKQGVSVAQKFVADGVKFVVGHFNSGVSIP 106
Cdd:cd06339 2 IALLLPLSGPYAAAGQAIRDGIELALFD------AGGSRPELRVYDT-GGPEGAAAAYQQAVAEGADLIIGPLLKSSVAA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 107 ASEIYAENGILQVTPASTNPQFTERGLW-NTFrtcgRDDQQGAVAGAYIAANFKDaKVAVIHDKTPYGQGLADETKKSMN 185
Cdd:cd06339 75 LAAAAQALGVPVLALNNDESATAGPGLFqFGL----SPEDEARQAARYAVQQGLR-RFAVLAPDNAYGQRVANAFREAWQ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 186 EAGVTEALYEGINTGDKDFSALIAKMKQAGVSI----------------------VYYGGLHTEAGLIMRQMKDQGL-KA 242
Cdd:cd06339 150 ALGGTVVAVESYDPDETDFSAAIRRLLGVDQSEarirqlgellefeprrrqdfdaIFLPAGPEQARLIAPQLAFYGAgDV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 243 TMMSGDGIVSNELASIAGDAVDGtlMTFA-PDPRKSPAAkdLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDP 320
Cdd:cd06339 230 PLLGTSLWYSGKLNLLRDPDLNG--AWFAdPPWLLSPRA--FPLRYRLAyGWPPPRLAALGYDAYRLAARLARLGGGLTP 305
|
330 340 350
....*....|....*....|....*....|
gi 1550354570 321 QAvaeaikakgPFKTAIGELGFDEKGDITR 350
Cdd:cd06339 306 GA---------GFSGLTGLLRLDPDGRIER 326
|
|
| PBP1_RPA0985_benzoate-like |
cd20013 |
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the ... |
27-330 |
9.91e-12 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0985 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0985 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380666 [Multi-domain] Cd Length: 356 Bit Score: 65.35 E-value: 9.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQ-AAEDINAAGGIngeQIKVVLGDDV-SDPKQGVSVAQKF-VADGVKFVVGHFNSGV 103
Cdd:cd20013 2 VGVIGPFSGPFADYGKQFDRGIDLyLKLHGDKVGGR---KVEVIYRDDGgPNPAVAKRLAQELiVRDKVQILIGFGFTPN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 104 SIPASEIYAENGILQVTPASTNPQFTERGLWNTfRTCGRDDQQGAVAGAYIAAN-FKDAKVAVIhDKTPyGQGLADETKK 182
Cdd:cd20013 79 ALAVAPVATEAKTPTVIMNAATSSITRKSPYFV-RTSFTMWQVAYPMGKWAAKNgIKKAYTAVA-DYAP-GHDAETAFKK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 183 SMNEAG--VTEALYEGINTgdKDFSALIAKMKQAGVSIVYY---GGLHTEAglIMRQMKDQGLKAT----MMSGDGIVSN 253
Cdd:cd20013 156 AFEAAGgkIVGSIRVPLAT--PDFAPFMQRIKDAKPDAVFVfvpAGAPSIG--FLKAYAERGLKEAgiklLGTGDATDDD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 254 ELASIaGDAVDGTL--MTFAPDpRKSPAAKDLVEKFRAAG---FEPEAYTLYAYAALQVIAEGAKA-AGNTDPQAVAEAI 327
Cdd:cd20013 232 DLPAM-GDAALGLItaGHYSAA-LDSPENKAFVAAYQKAYgpdARPDFMAVAAYDGMALIYKMIKAtGGKFDGDKAMAAV 309
|
...
gi 1550354570 328 KAK 330
Cdd:cd20013 310 KGL 312
|
|
| PBP1_AmiC |
cd06357 |
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ... |
27-345 |
5.97e-11 |
|
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.
Pssm-ID: 380580 [Multi-domain] Cd Length: 357 Bit Score: 62.98 E-value: 5.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSgvsi 105
Cdd:cd06357 2 VGLLFSQTGVTAIIEQSMLNGALLAIEEINAAGGVNGRPIEPVVYDPASDPDRYRELAERLLLeDGVRHIFGCYTS---- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 pAS------EIYAENGILqVTPAS-----TNPqfterglwNTFRTCGRDDQQGAVAGAYIAANFKdAKVAVIHDKTPYGQ 174
Cdd:cd06357 78 -ASrkavlpVVERHNALL-WYPTPyegfeYSP--------NVIYTGAVPNQHLLPLARYLLAHFG-KRVFLVGSNYVYPW 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 175 GLADETKKSMNEAG--VTEALYEGIntGDKDFSALIAKMKQAGVSIVYygglhteAGLI-------MRQMKDQGLKATMM 245
Cdd:cd06357 147 ESNRVARELIEASGgeVVGERYVPL--GDTDFAEIIEEIKSLKPDVVF-------STLVgdsiyafYRAYAEAGLDPADM 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 246 SgdgIVS-----NELASIAGDAVDGTLmTFAP--DPRKSPAAKDLVEKFRAAGFEPEAYTLY---AYAALQVIAEGAKAA 315
Cdd:cd06357 218 P---IASlttseAEVAAIGAEAAAGHY-TSAPyfQSIDTPENRAFVEAYRARFGDDAVTSAVaeaAYFQVHLLARAIERA 293
|
330 340 350
....*....|....*....|....*....|
gi 1550354570 316 GNTDPQAVAEAIKaKGPFKTAIGELGFDEK 345
Cdd:cd06357 294 GSDDPEAIRAALY-GQEFDAPQGPVRIDPD 322
|
|
| PBP1_GPCR_family_C-like |
cd06350 |
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory ... |
95-241 |
6.06e-11 |
|
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate; categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (m; Ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate and are categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs). The metabotropic glutamate receptors (mGluR) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. The mGluRs are coupled to G proteins and are thus distinct from the iGluRs which internally contain ligand-gated ion channels. The mGluR structure is divided into three regions: the extracellular region, the seven-spanning transmembrane region and the cytoplasmic region. The extracellular region is further divided into the ligand-binding domain (LBD) and the cysteine-rich domain. The LBD has sequence similarity to the LIVBP, which is a bacterial periplasmic protein (PBP), as well as to the extracellular region of both iGluR and the gamma-aminobutyric acid (GABA)b receptor. iGluRs are divided into three main subtypes based on pharmacological profile: NMDA, AMPA, and kainate receptors. All family C GPCRs have a large extracellular N terminus that contain a domain with homology to bacterial periplasmic amino acid-binding proteins.
Pssm-ID: 380573 Cd Length: 350 Bit Score: 63.08 E-value: 6.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 95 VVGHFNSGVSIPASEIYAENGILQVTPASTNPQFTERGLWNTF-RTCGRDDQQgAVAGAYIAANFKDAKVAVIHDKTPYG 173
Cdd:cd06350 98 VIGAASSSVSIAVANLLGLFKIPQISYASTSPELSDKIRYPYFlRTVPSDTLQ-AKAIADLLKHFNWNYVSTVYSDDDYG 176
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1550354570 174 QGLADETKKSMNEAGVTEALYEGI--NTGDKDFSALIAKMKQAGVS--IVYYGGLHtEAGLIMRQMKDQGLK 241
Cdd:cd06350 177 RSGIEAFEREAKERGICIAQTIVIpeNSTEDEIKRIIDKLKSSPNAkvVVLFLTES-DARELLKEAKRRNLT 247
|
|
| PBP1_SBP-like |
cd06327 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
33-329 |
1.66e-10 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380550 [Multi-domain] Cd Length: 336 Bit Score: 61.43 E-value: 1.66e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 33 LTGPNAAFGAQLqkgaeqAAEDinAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFV-ADGVKFVVGHFNSGVSIPASEIY 111
Cdd:cd06327 15 LSGPGSVEAAKM------AVED--FGGKVLGRPIEVVSADHQNKPDVASAIAREWYdRDGVDAIVDVPNSAVALAVQKLA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 112 AENGILQVTPASTNPQFTERG--------LWNTFrtcgrddQQGAVAGAYIAANFKDaKVAVIHDKTPYGQGLADETKKS 183
Cdd:cd06327 87 KEKKKIAIVTGAGSSDLTGKAcspygvhwAYDTY-------ALARGTVKALVKQGGK-SWFFITADYAFGHSLEADATAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 184 MNEAG---VTEALYEgINTGdkDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMS--GDGIVSNELASI 258
Cdd:cd06327 159 VKAAGgkvVGSVRHP-LGTT--DFSSFLLQAQASGADVIALANAGADLVNAVKQAREFGLTDGGQKlaALLLFITDIHAL 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1550354570 259 AGDAVDGTLMTFAPDPRKSPAAKDLVEKFRAA-GFEPEAYTLYAYAALQVIAEGAKAAGNTDPQAVAEAIKA 329
Cdd:cd06327 236 GLDAAQGLYLTTAFYWDRDDATRAWAKRFFARtGKMPTMLQAGVYSAVLHYLKAVKAAGTDDADAVVAKMRE 307
|
|
| PBP1_FmdD-like |
cd06355 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
27-328 |
6.17e-10 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380578 [Multi-domain] Cd Length: 347 Bit Score: 59.90 E-value: 6.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQK-FVADGVKFVVGHFNSG--- 102
Cdd:cd06355 2 VGILHSLSGTMAISERPLVDATLLAIDEINAAGGLLGRKIEPVIEDGASDWPTFAEKAEKlITQDKVAVIFGCWTSAsrk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 103 -VsIPASEiyAENGILqvtpasTNPQFTErGLW---NTFRTCGRDDQQGAVAGAYIAANFKDaKVAVIHDKTPYGQGLAD 178
Cdd:cd06355 82 aV-LPVIE--KYNGLL------FYPVQYE-GLEqspNIVYTGATPNQQILPAIDWLLENLGK-RFFLVGSDYVFPRTANK 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 179 ETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVY--YGGLHTEAglIMRQMKDQGLKAT---MMSgdgiVS- 252
Cdd:cd06355 151 IIRDQLKALGGEVVGEEYVPLGGTDFDAIVAKIKAFKPDVIVntLNGDSNIA--FFKQLAAAGITASdlpVLS----FSv 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 253 --NELASIAGDAVDGTLMTFAPDPR-KSPAAKDLVEKFRAAgFEPEAYT----LYAYAALQVIAEGAKAAGNTDPQAVAE 325
Cdd:cd06355 225 seAELRAIGPEELAGHYAAWNYFQSlDTPENQAFVEAFKAK-YGADRVTsdpmEAAYLGVYLWAQAVEKAGSFDPDAVRA 303
|
...
gi 1550354570 326 AIK 328
Cdd:cd06355 304 ALK 306
|
|
| Peripla_BP_5 |
pfam13433 |
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ... |
25-328 |
5.04e-09 |
|
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins.
Pssm-ID: 463875 [Multi-domain] Cd Length: 363 Bit Score: 57.22 E-value: 5.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 25 ILVGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVA-DGVKFVVGHFNSgv 103
Cdd:pfam13433 1 IKVGVLHSLTGTMAISERSLKDATLMAIEEINAAGGVLGRKIEPVVVDPASDWPLFAEKARKLIDqDKVRVVFGCWTS-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 104 sipaseiyaengilqVTPASTNPQFTERG--LW------------NTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDK 169
Cdd:pfam13433 79 ---------------ASRKAVLPVFERHNglLFypvqyegfessrNIFYTGAAPNQQAIPAVDYLLSELGKRFFLVGSDY 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 170 T-PYgqgladETKKSMNEA----GVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATM 244
Cdd:pfam13433 144 VyPR------TTNRILRAYlkakGGEVVGERYLPLGSSDWQSIVAKIKAAGPDVVFSTINGDSNVAFYRALRAAGITAED 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 245 MSgdgIVS-----NELASIAGDAVDGTLMT---FAPDPrkSPAAKDLVEKFRAAgFEPEAYT----LYAYAALQVIAEGA 312
Cdd:pfam13433 218 IP---VMSfsvaeEELAGMGPEPLVGHLAAwnyFQSLD--TPENKAFVAAFKAR-YGDDRVTndpmEAAYIGVHLWAQAV 291
|
330
....*....|....*.
gi 1550354570 313 KAAGNTDPQAVAEAIK 328
Cdd:pfam13433 292 EKAGTDDPDAVRQAML 307
|
|
| PBP1_NHase |
cd06358 |
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively ... |
27-327 |
3.74e-08 |
|
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides; This group includes the type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides, which are subsequently converted by amidases to yield free carboxylic acids and ammonia. NHases from bacteria and fungi have been purified and characterized. In Rhodococcus sp., the nitrile hydratase operon consists of six genes encoding NHase regulator 2, NHase regulator 1, amidase, NHase alpha subunit, NHase beta subunit, and NHase activator. The operon produces a constitutive hydratase that has a broad substrate spectrum: aliphatic and aromatic nitriles, mononitriles and dinitriles, hydroxynitriles and amino-nitriles, and a constitutive amidase of equally low substrate specificity. NHases are metalloenzymes containing either cobalt or iron, and therefore can be classified into two subgroups: ferric NHases and cobalt NHases.
Pssm-ID: 380581 [Multi-domain] Cd Length: 333 Bit Score: 54.52 E-value: 3.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 27 VGVGGPLTGPNAAFGAQLQKGAEQAAEDINAAGGINGEQIKVVLGDDVSDPKQGVSVAQKFVADG-VKFVVGHFNSGVSI 105
Cdd:cd06358 2 IGLLIPLSGPAGLWGPSCEACAELAAAEINAAGGILGREVELVLIDAGGPPAEVAAAARRLVDDGaVDAIVGMHTSAVRQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 106 PASE--------IYAengilqvtpastnPQFT--ERGLWnTFRTCGRDDQQGAVAGAYIAANFKDAKVAVIHDKTPYGQG 175
Cdd:cd06358 82 ALANavggrvpyVYT-------------PLYEggERTPG-VYAIGETPEEQLRPALRWLADERRVRRWFLVGNDYVWPRA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 176 LADETKKSMNEAGVTEALYEGINTGDKDFSALIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGLKATMMSGDGIV-SNE 254
Cdd:cd06358 148 SHAAARRYIARLGGEVVGERFVPLGEDDFERVLARIRASRPDAVLISLVGQDAVDFNRAFAAAGLAGRILRLSPAIdENV 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 255 LASIAGDAVDGtLMTFAP--DPRKSPAAKDLVEKFRAAgFEPEAYTLYAYA-----ALQVIAEGAKAAGNTDPQAVAEAI 327
Cdd:cd06358 228 LLAIGADATEN-LYSASGyfASLRTAANLAFLERYHAA-FGDRAPPLNALGescyeGVHFLAALARRAGSLDVRALAAAA 305
|
|
| PBP1_GABAb_receptor |
cd06366 |
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for ... |
29-240 |
5.07e-08 |
|
ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA); Ligand-binding domain of GABAb receptors, which are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380589 [Multi-domain] Cd Length: 404 Bit Score: 54.17 E-value: 5.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 29 VGG--PLTGPNAAF-GAQLQKGAEQAAEDINAAGGI-NGEQIKVVLGDDVSDPKQGVSVAQKFVADGVKFVV--GHFNSG 102
Cdd:cd06366 2 IGGlfPLSGSKGWWgGAGILPAAEMALEHINNRSDIlPGYNLELIWNDTQCDPGLGLKALYDLLYTPPPKVMllGPGCSS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 103 VSIPASEIYAENGILQVTPASTNPQFTERGLW-NTFRTCGRDDQQGAvagAYIA--ANFKDAKVAVIHDKTPYGQGLADE 179
Cdd:cd06366 82 VTEPVAEASKYWNLVQLSYAATSPALSDRKRYpYFFRTVPSDTAFNP---ARIAllKHFGWKRVATIYQNDEVFSSTAED 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1550354570 180 TKKSMNEAGVTEALYEGINTGDKDFSalIAKMKQAGVSIVYYGGLHTEAGLIMRQMKDQGL 240
Cdd:cd06366 159 LEELLEEANITIVATESFSSEDPTDQ--LENLKEKDARIIIGLFYEDAARKVFCEAYKLGM 217
|
|
| PBP1_mGluR |
cd06362 |
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of ... |
87-254 |
8.57e-07 |
|
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of the metabotropic glutamate receptors (mGluR), which are members of the family C of G-protein-coupled receptors that transduce extracellular signals into G-protein activation and ultimately into cellular responses. mGluRs bind to glutamate and function as an excitatory neurotransmitter; they are involved in learning, memory, anxiety, and the perception of pain. Eight subtypes of mGluRs have been cloned so far, and are classified into three groups according to their sequence similarities, transduction mechanisms, and pharmacological profiles. Group I is composed of mGlu1R and mGlu5R that both stimulate PLC hydrolysis. Group II includes mGlu2R and mGlu3R, which inhibit adenylyl cyclase, as do mGlu4R, mGlu6R, mGlu7R, and mGlu8R, which form group III.
Pssm-ID: 380585 [Multi-domain] Cd Length: 460 Bit Score: 50.75 E-value: 8.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 87 FVADGVKFVVGHFNSGVSIPASEIYAENGILQVTPASTNPQFTERGLWNTF-RTCGRDDQQgAVAGAYIAANFKDAKVAV 165
Cdd:cd06362 103 FQFYDVVGVIGAESSSVSIQVANLLRLFKIPQISYASTSDELSDKERYPYFlRTVPSDSFQ-AKAIVDILLHFNWTYVSV 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1550354570 166 IHDKTPYGQGLADETKKSMNEAGVTEALYEGINT--GDKDFSALIAKMKQ---AGVSIVYYGGLHTEAglIMRQMKDQGL 240
Cdd:cd06362 182 VYSEGSYGEEGYKAFKKLARKAGICIAESERISQdsDEKDYDDVIQKLLQkknARVVVLFADQEDIRG--LLRAAKRLGA 259
|
170
....*....|....*.
gi 1550354570 241 --KATMMSGDGIVSNE 254
Cdd:cd06362 260 sgRFIWLGSDGWGTNI 275
|
|
| |
