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Conserved domains on  [gi|1556558126|gb|RWQ77688|]
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ABC transporter permease [Bacillus cereus]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-305 8.01e-118

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 341.66  E-value: 8.01e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126   1 MGRYVLKRFVYMALTLFLITTLTFFLMKLLPGSPLKNQ--EKLSPAQKEIILEKYGLNDPVPVQYARYLGNLAKGDLGVS 78
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALlgPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  79 FQYdNRPVTDMIVDRIGPSAQLGLQAIILGTFIGLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVGVKL 158
Cdd:COG0601    81 FVY-GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 159 GWFPVA--------FWKGPEFTVMPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPV 230
Cdd:COG0601   160 GWLPVSgrvspwedFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPV 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1556558126 231 VTILGPMVAALITGTLVIEQIYAVPGLGEQFVKSITLNDYTVIMGTTIFYSAIFILVIFIVDILYGIIDPRIRLA 305
Cdd:COG0601   240 VTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-305 8.01e-118

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 341.66  E-value: 8.01e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126   1 MGRYVLKRFVYMALTLFLITTLTFFLMKLLPGSPLKNQ--EKLSPAQKEIILEKYGLNDPVPVQYARYLGNLAKGDLGVS 78
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALlgPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  79 FQYdNRPVTDMIVDRIGPSAQLGLQAIILGTFIGLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVGVKL 158
Cdd:COG0601    81 FVY-GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 159 GWFPVA--------FWKGPEFTVMPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPV 230
Cdd:COG0601   160 GWLPVSgrvspwedFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPV 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1556558126 231 VTILGPMVAALITGTLVIEQIYAVPGLGEQFVKSITLNDYTVIMGTTIFYSAIFILVIFIVDILYGIIDPRIRLA 305
Cdd:COG0601   240 VTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-303 2.96e-82

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 250.75  E-value: 2.96e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126   1 MGRYVLKRFVYMALTLFLITTLTFFLMKLLPGSPLKNQEKLSPAQKEIILEKYGLNDPVPVQYARYLGNLAKGDLGVSFQ 80
Cdd:PRK09471    1 MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  81 YDNRPVTDMIVDRIGPSAQLGLQAIILGTFIGLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVGVKLGW 160
Cdd:PRK09471   81 YKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLHW 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 161 FPVAFWKG--PEFTVMPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILGPMV 238
Cdd:PRK09471  161 LPGGGWNGgaLKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAF 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1556558126 239 AALITGTLVIEQIYAVPGLGEQFVKSITLNDYTVIMGTTIFYSAIFILVIFIVDILYGIIDPRIR 303
Cdd:PRK09471  241 VGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 112-303 1.19e-27

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 105.84  E-value: 1.19e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 112 GLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYfvgvklgwfpVAFWKGPEFTVMPTIALSMGVIATIARFS 191
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVV----------IAILSILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 192 RAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILGPMVAALITGTLVIEQIYAVPGLGEQFVKSITLNDYT 271
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1556558126 272 VIMGTTIFYSAIFILVIFIVDILYGIIDPRIR 303
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 94-293 6.38e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 77.32  E-value: 6.38e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  94 IGPSAQLGLQAIILGTFIGLILGIVAAlRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVGVKLGWFPVAFWkgpeftV 173
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILA-RKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL------G 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 174 MPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILGPMVAALITGTLVIEQIYA 253
Cdd:cd06261    74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1556558126 254 VPGLGeqfVKSITLNDYTVIMGTTIFYSAIFILVIFIVDI 293
Cdd:cd06261   154 GEAPG---PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-305 8.01e-118

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 341.66  E-value: 8.01e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126   1 MGRYVLKRFVYMALTLFLITTLTFFLMKLLPGSPLKNQ--EKLSPAQKEIILEKYGLNDPVPVQYARYLGNLAKGDLGVS 78
Cdd:COG0601     1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALlgPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  79 FQYdNRPVTDMIVDRIGPSAQLGLQAIILGTFIGLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVGVKL 158
Cdd:COG0601    81 FVY-GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 159 GWFPVA--------FWKGPEFTVMPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPV 230
Cdd:COG0601   160 GWLPVSgrvspwedFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPV 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1556558126 231 VTILGPMVAALITGTLVIEQIYAVPGLGEQFVKSITLNDYTVIMGTTIFYSAIFILVIFIVDILYGIIDPRIRLA 305
Cdd:COG0601   240 VTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-303 2.96e-82

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 250.75  E-value: 2.96e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126   1 MGRYVLKRFVYMALTLFLITTLTFFLMKLLPGSPLKNQEKLSPAQKEIILEKYGLNDPVPVQYARYLGNLAKGDLGVSFQ 80
Cdd:PRK09471    1 MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  81 YDNRPVTDMIVDRIGPSAQLGLQAIILGTFIGLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVGVKLGW 160
Cdd:PRK09471   81 YKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLHW 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 161 FPVAFWKG--PEFTVMPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILGPMV 238
Cdd:PRK09471  161 LPGGGWNGgaLKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAF 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1556558126 239 AALITGTLVIEQIYAVPGLGEQFVKSITLNDYTVIMGTTIFYSAIFILVIFIVDILYGIIDPRIR 303
Cdd:PRK09471  241 VGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-303 1.31e-66

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 210.73  E-value: 1.31e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126   1 MGRYVLKRFVYMALTLFLITTLTFFLMKLLPGSP--LKNQEKLSPAQKEIILEKYGLNDPVPVQYARYLGNLAKGDLGVS 78
Cdd:PRK15081    1 MLNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDParLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  79 FQyDNRPVTDMIVDRIGPSAQLGLQAIILGTFIGLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVGVKL 158
Cdd:PRK15081   81 MV-SRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVEL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 159 GWFPVAFWKGPEFTVMPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILGPMV 238
Cdd:PRK15081  160 GWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQF 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1556558126 239 AALITGTLVIEQIYAVPGLGEQFVKSITLNDYTVIMGTTIFYSAIFILVIFIVDILYGIIDPRIR 303
Cdd:PRK15081  240 GFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-307 3.96e-56

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 184.13  E-value: 3.96e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126   1 MGRYVLKRFVYMALTLFLITTLTFFLMKLLPGSPLKNQEKLS-----PAQKEIILEKYGLNDPVPVQYARYLGNLAKGDL 75
Cdd:PRK10352    1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSnlpptPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  76 GVSFQyDNRPVTDMIVDRIGPSAQLGLQAIILGTFIGLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVG 155
Cdd:PRK10352   81 GISFA-TQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 156 VKLGWFPVAFWKGPEFTVMPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILG 235
Cdd:PRK10352  160 VYLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVG 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1556558126 236 PMVAALITGTLVIEQIYAVPGLGEQFVKSITLNDYTVIMGTTIFYSAIFILVIFIVDILYGIIDPRIRLAGG 307
Cdd:PRK10352  240 MHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEG 311
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
29-303 1.68e-46

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 159.98  E-value: 1.68e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  29 LLPGSP---LKNQEKLSPAQKEIILEKYGLNDPVPVQYARYLGNLAKGDLGVSFQyDNRPVTDMIVDRIGPSAQLGLQAI 105
Cdd:PRK10914   29 MIPGDPvmiMAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISLK-SRIPVWDEFVPRFKATLELGVCAM 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 106 ILGTFIGLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVGVKLGWFPVA--------------------- 164
Cdd:PRK10914  108 IFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSgrvsdmvflddsnpltgfmli 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 165 ---FWKGP-------EFTVMPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTIL 234
Cdd:PRK10914  188 dtaIWGEDgnfidavAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVI 267

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1556558126 235 GPMVAALITGTLVIEQIYAVPGLGEQFVKSITLNDYTVIMGTTIFYSAIFILVIFIVDILYGIIDPRIR 303
Cdd:PRK10914  268 GLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIR 336
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 41-306 2.19e-28

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 112.15  E-value: 2.19e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  41 LSPAQKEIILEKYGLNDPVPVQYARYLGNLAKGDLGVSFqYDNRPVTDMIVDRIGPSAQLGLQAIILGTFIGLILGIVAA 120
Cdd:PRK15133   81 LDPEVIAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSL-FRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKA 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 121 LRNNTWVDYSATVISVLGMSVPSFVFAALLQYFV--GVKLGWFPVAFWKGPEFT---------------VMPTIALSMGV 183
Cdd:PRK15133  160 VRNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFagGSYFDLFPLRGLVSANFDslpwyqkitdylwhiTLPVLATVIGG 239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 184 IATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVT-ILGPMVAALITGTLVIEQIYAVPGLGEQFV 262
Cdd:PRK15133  240 FAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAgFPATFISMFFTGSLLIEVMFSLNGLGLLGY 319

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1556558126 263 KSITLNDYTVIMGTTIFYSAIFILVIFIVDILYGIIDPRIRLAG 306
Cdd:PRK15133  320 EATVSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRIDFEG 363
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 112-303 1.19e-27

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 105.84  E-value: 1.19e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 112 GLILGIVAALRNNTWVDYSATVISVLGMSVPSFVFAALLQYfvgvklgwfpVAFWKGPEFTVMPTIALSMGVIATIARFS 191
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVV----------IAILSILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 192 RAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILGPMVAALITGTLVIEQIYAVPGLGEQFVKSITLNDYT 271
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1556558126 272 VIMGTTIFYSAIFILVIFIVDILYGIIDPRIR 303
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
PRK15110 PRK15110
peptide ABC transporter permease SapB;
63-300 4.47e-26

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 105.16  E-value: 4.47e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  63 YARYLGNLAKGDLGVSfQYDNRPVTDMIVDRIGPSAQLGLQAIILGTFIGLILGIVAALRNNTWVDYSATVISVLGMSVP 142
Cdd:PRK15110   44 WVFWFNGLLHWDFGVS-SINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIP 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 143 SFVFAALLQYFVGVKLGWFPVA-------------------FWKGPE------------FTVMPTIALSMGVIATIARFS 191
Cdd:PRK15110  123 VFWLALLLTLFFSLTLGWLPVSgrfdllyevkpvtgfalidAWLSDSpwrdemimsairHMILPVITLAVAPTTEVIRLM 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 192 RAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILGPMVAALITGTLVIEQIYAVPGLGEQFVKSITLNDYT 271
Cdd:PRK15110  203 RISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYA 282

                         250       260
                  ....*....|....*....|....*....
gi 1556558126 272 VIMGTTIFYSAIFILVIFIVDILYGIIDP 300
Cdd:PRK15110  283 AISAGVMVVGSLVIIVNVLSDILGAMANP 311
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 94-293 6.38e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 77.32  E-value: 6.38e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  94 IGPSAQLGLQAIILGTFIGLILGIVAAlRNNTWVDYSATVISVLGMSVPSFVFAALLQYFVGVKLGWFPVAFWkgpeftV 173
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILA-RKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL------G 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 174 MPTIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILGPMVAALITGTLVIEQIYA 253
Cdd:cd06261    74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1556558126 254 VPGLGeqfVKSITLNDYTVIMGTTIFYSAIFILVIFIVDI 293
Cdd:cd06261   154 GEAPG---PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 97-242 7.60e-12

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 64.36  E-value: 7.60e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  97 SAQLGLQAIILGTFIGLILGIVAALRNNtWVDysaTVISVLG---MSVPSFVFAALLQYFVGVklGWFPVAfwkgpeftv 173
Cdd:COG1173    81 SLLVGLLAVLIALVIGVLLGLLAGYFGG-WVD---AVLMRLVdvlLAFPSLLLAIALVAVLGP--GLLNVI--------- 145

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1556558126 174 mptIALSMGVIATIARFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNALIPVVTILGPMVAALI 242
Cdd:COG1173   146 ---LALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAI 211
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 96-300 1.08e-06

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 49.60  E-value: 1.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126  96 PSAQ--LGLQA--------IILGTFIGLILGIVAALRNntwvdysatviSVLGmsvpsfVFAALLQYFVGVKL---GWFP 162
Cdd:PRK15021  117 PSRQnwLGTDAnggdvlarILYGTRISVLFGLMLTLCS-----------SVMG------VLAGALQGYYGGKVdlwGQRF 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 163 VAFWKG---------------PEFTVMPTIALSMGVIATIArFSRAELIEVMQADYILTAKAKGISQGVIIVKHALRNAL 227
Cdd:PRK15021  180 IEVWSGmptlfliillssvvqPNFWWLLAITVLFGWMSLVG-VVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAM 258

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126 228 IPVVTILGPMVAALITGTLVIEQI-----YAVPGLGEQFVKSITlNDYTVIMGTTIFYS-AIFI-LVIFIVDILYGIIDP 300
Cdd:PRK15021  259 VATLTFLPFILCSSITTLTSLDFLgfglpLGSPSLGELLLQGKN-NLQAPWLGITAFLSvAILLsLLIFIGEAVRDAFDP 337
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 1-93 4.86e-05

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 41.82  E-value: 4.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1556558126   1 MGRYVLKRFVYMALTLFLITTLTFFLMKLLPGSP--LKNQEKLSPAQKEIILEKYGLNDPVPVQYARYLGNLAKGD---- 74
Cdd:pfam19300   1 MLRFLVRRTLGAVVILLIISAVTFFLFYAIPRDParLACGKNCTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGRdfga 80

                          90       100
                  ....*....|....*....|....*..
gi 1556558126  75 --------LGVSFQyDNRPVTDMIVDR 93
Cdd:pfam19300  81 vghcpapcLGYSFA-NNEPVWDTIMDR 106
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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