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Conserved domains on  [gi|1560390145|gb|RXA76190|]
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ABC transporter ATP-binding protein [Enterococcus hirae]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11438141)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates, similar to iron (ferric) import ATP-binding proteins

CATH:  3.40.50.300
Gene Ontology:  GO:0042626|GO:0140359|GO:0016887|GO:0005524
PubMed:  25750732|24638992|12370001
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 7-258 3.07e-130

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


:

Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 368.99  E-value: 3.07e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA 86
Cdd:COG1120     2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYVP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:COG1120    82 QEPPAPFGLTVRELVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQI 246
Cdd:COG1120   162 DEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELLEEVYGVEARV 241

                         250
                  ....*....|..
gi 1560390145 247 IELPETNKPVVL 258
Cdd:COG1120   242 IEDPVTGRPLVL 253
 
Name Accession Description Interval E-value
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 7-258 3.07e-130

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 368.99  E-value: 3.07e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA 86
Cdd:COG1120     2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYVP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:COG1120    82 QEPPAPFGLTVRELVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQI 246
Cdd:COG1120   162 DEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELLEEVYGVEARV 241

                         250
                  ....*....|..
gi 1560390145 247 IELPETNKPVVL 258
Cdd:COG1120   242 IEDPVTGRPLVL 253
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
5-255 1.80e-99

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 291.15  E-value: 1.80e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   5 TTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:PRK11231    1 MTLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:PRK11231   81 LPQHHLTPEGITVRELVAYGRSPWLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMsIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEA 244
Cdd:PRK11231  161 LLDEPTTYLDINHQVELMRLMRELNTQGKTVVTV-LHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTPGLLRTVFDVEA 239

                         250
                  ....*....|.
gi 1560390145 245 QIIELPETNKP 255
Cdd:PRK11231  240 EIHPEPVSGTP 250
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 8-225 1.11e-80

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 240.80  E-value: 1.11e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   8 EAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQ 87
Cdd:cd03214     1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVPQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 ssehplgmtveevvsygrypyqkffsglneedlhaiqwALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILD 167
Cdd:cd03214    81 --------------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLD 122

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 168 EPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03214   123 EPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 17-252 2.98e-49

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 163.78  E-value: 2.98e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  17 LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA---QKIALLAQSSEHPL 93
Cdd:TIGR04521  16 FEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKdlrKKVGLVFQFPEHQL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 -GMTVEEVVSYGryPyQKFfsGLNEEDLHA-IQWALEATQLT-KLKERELSSLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:TIGR04521  96 fEETVYKDIAFG--P-KNL--GLSEEEAEErVKEALELVGLDeEYLERSPFELSGGQMRRVAIAGVLAMEPEVLILDEPT 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 171 TFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVittswMREIYEIEAQIIELP 250
Cdd:TIGR04521 171 AGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREV-----FSDVDELEKIGLDVP 245


                  ..
gi 1560390145 251 ET 252
Cdd:TIGR04521 246 EI 247
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
15-208 1.98e-45

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 151.23  E-value: 1.98e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  15 GYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEistyspkmlaqKIALLAQSSEHP-- 92
Cdd:NF040873    1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGA-----------RVAYVPQRSEVPds 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  93 LGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:NF040873   70 LPLTVRDLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1560390145 173 LDPAHQLEILHLLKEInHIKQTTILMSIHDINHASR 208
Cdd:NF040873  150 LDAESRERIIALLAEE-HARGATVVVVTHDLELVRR 184
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 25-171 2.36e-35

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 123.91  E-value: 2.36e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPLGMTVEEVVSYG 104
Cdd:pfam00005   4 VSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENLRLG 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 105 RYPYQKFFSGLNEEdlhaIQWALEATQLTKLKEREL----SSLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:pfam00005  84 LLLKGLSKREKDAR----AEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
26-230 7.56e-17

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 80.17  E-value: 7.56e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKsftrLLP----VKEGKIIVDGSEIStySPK---MLAQKIALLAQSsehpLG---- 94
Cdd:NF033858   21 SLDIPAGCMVGLIGPDGVGKSSLLS----LIAgarkIQQGRVEVLGGDMA--DARhrrAVCPRIAYMPQG----LGknly 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 --MTVEEVVSygrypyqkFFS---GLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDE 168
Cdd:NF033858   91 ptLSVFENLD--------FFGrlfGQDAAERRRrIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDE 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 169 PTTFLDPAH-----QLeilhllkeINHIKQT----TILMSIHDINHASRFsDYLIGMKAGQIVVQGTPDEV 230
Cdd:NF033858  163 PTTGVDPLSrrqfwEL--------IDRIRAErpgmSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAEL 224
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
26-231 5.03e-12

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 65.53  E-value: 5.03e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKI-----IVDGSEISTyspkmlAQKIALLAQSsehplgmtveev 100
Cdd:NF033858  286 SFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAwlfgqPVDAGDIAT------RRRVGYMSQA------------ 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 vsygrypyqkfFSgLNEE-------DLHA-------------IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:NF033858  348 -----------FS-LYGEltvrqnlELHArlfhlpaaeiaarVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHK 415

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:NF033858  416 PELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIFISTHFMNEAER-CDRISLMHAGRVLASDTPAALV 485
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 32-205 6.09e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.53  E-value: 6.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   32 GKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIstyspkmlaqkiallaqssehplgmtveevvsygrypyqkf 111
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGED----------------------------------------- 40

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  112 fsglneedlhaIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEIL-----HLLK 186
Cdd:smart00382  41 -----------ILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLlleelRLLL 109

                          170
                   ....*....|....*....
gi 1560390145  187 EINHIKQTTILMSIHDINH 205
Cdd:smart00382 110 LLKSEKNLTVILTTNDEKD 128
GguA NF040905
sugar ABC transporter ATP-binding protein;
26-211 8.47e-08

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.87  E-value: 8.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP--VKEGKIIVDGSEISTYSPK--------MLAQKIALLaqssehPLgM 95
Cdd:NF040905   21 NLSVREGEIHALCGENGAGKSTLMKVLSGVYPhgSYEGEILFDGEVCRFKDIRdsealgivIIHQELALI------PY-L 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 TVEEVVsygrypyqkfFSGlNEedlHA----IQWA---LEATQLTK---LKER---ELSSLSGGQAQRVWIAMALAQEAD 162
Cdd:NF040905   94 SIAENI----------FLG-NE---RAkrgvIDWNetnRRARELLAkvgLDESpdtLVTDIGVGKQQLVEIAKALSKDVK 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 163 ILILDEPTTFL---DPAHQLEILHLLKEinhikQ--TTILMSiHDINHASRFSD 211
Cdd:NF040905  160 LLILDEPTAALneeDSAALLDLLLELKA-----QgiTSIIIS-HKLNEIRRVAD 207
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
127-249 1.36e-06

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 48.96  E-value: 1.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 127 LEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHA 206
Cdd:NF000106  129 LERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVR-DGATVLLTTQYMEEA 207

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1560390145 207 SRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQIIEL 249
Cdd:NF000106  208 EQLAHELTVIDRGRVIADGKVDELKTKVGGRTLQIRPAHAAEL 250
 
Name Accession Description Interval E-value
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 7-258 3.07e-130

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 368.99  E-value: 3.07e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA 86
Cdd:COG1120     2 LEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELARRIAYVP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:COG1120    82 QEPPAPFGLTVRELVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEPPLLLL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQI 246
Cdd:COG1120   162 DEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPEEVLTPELLEEVYGVEARV 241

                         250
                  ....*....|..
gi 1560390145 247 IELPETNKPVVL 258
Cdd:COG1120   242 IEDPVTGRPLVL 253
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
5-255 1.80e-99

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 291.15  E-value: 1.80e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   5 TTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:PRK11231    1 MTLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:PRK11231   81 LPQHHLTPEGITVRELVAYGRSPWLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMsIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEA 244
Cdd:PRK11231  161 LLDEPTTYLDINHQVELMRLMRELNTQGKTVVTV-LHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTPGLLRTVFDVEA 239

                         250
                  ....*....|.
gi 1560390145 245 QIIELPETNKP 255
Cdd:PRK11231  240 EIHPEPVSGTP 250
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
 7-261 2.44e-91

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 270.42  E-value: 2.44e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA 86
Cdd:COG4604     2 IEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAKRLAILR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYGRYPYQKffsG-LNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:COG4604    82 QENHINSRLTVRELVAFGRFPYSK---GrLTAEDREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQ 245
Cdd:COG4604   159 LDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEEIITPEVLSDIYDTDIE 238

                         250
                  ....*....|....*.
gi 1560390145 246 IIELPetNKPVVLSYD 261
Cdd:COG4604   239 VEEID--GKRICVYFR 252
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
12-258 2.01e-81

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 245.67  E-value: 2.01e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  12 ITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEH 91
Cdd:PRK10253   13 LTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATT 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  92 PLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:PRK10253   93 PGDITVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTT 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 172 FLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQIIELPE 251
Cdd:PRK10253  173 WLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPV 252


                  ....*..
gi 1560390145 252 TNKPVVL 258
Cdd:PRK10253  253 AGTPLVV 259
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 8-225 1.11e-80

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 240.80  E-value: 1.11e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   8 EAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQ 87
Cdd:cd03214     1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVPQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 ssehplgmtveevvsygrypyqkffsglneedlhaiqwALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILD 167
Cdd:cd03214    81 --------------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLD 122

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 168 EPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03214   123 EPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 5-258 2.60e-73

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 224.65  E-value: 2.60e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   5 TTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:PRK13548    1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSehPLG--MTVEEVVSYGRYPYqkffSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEAD 162
Cdd:PRK13548   81 LPQHS--SLSfpFTVEEVVAMGRAPH----GLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAQLWE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 163 ------ILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWM 236
Cdd:PRK13548  155 pdgpprWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADGTPAEVLTPETL 234

                         250       260
                  ....*....|....*....|..
gi 1560390145 237 REIYEIEAQIIELPETNKPVVL 258
Cdd:PRK13548  235 RRVYGADVLVQPHPETGAPLVL 256
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-248 3.70e-73

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 223.81  E-value: 3.70e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSeistySPKMLAQ 80
Cdd:COG1121     1 MMMMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGK-----PPRRARR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 KIALLAQSSEHPLG--MTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALA 158
Cdd:COG1121    76 RIGYVPQRAEVDWDfpITVRDVVLMGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 159 QEADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMkAGQIVVQGTPDEVITTSWMRE 238
Cdd:COG1121   156 QDPDLLLLDEPFAGVDAATEEALYELLRELRR-EGKTILVVTHDLGAVREYFDRVLLL-NRGLVAHGPPEEVLTPENLSR 233

                         250
                  ....*....|
gi 1560390145 239 IYEIEAQIIE 248
Cdd:COG1121   234 AYGGPVALLA 243
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
7-258 3.72e-72

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 221.91  E-value: 3.72e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA 86
Cdd:COG4559     2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELARRRAVLP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYGRYPYQkffsGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQ------- 159
Cdd:COG4559    82 QHSSLAFPFTVEEVVALGRAPHG----SSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAQlwepvdg 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 160 EADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREI 239
Cdd:COG4559   158 GPRWLFLDEPTSALDLAHQHAVLRLARQLAR-RGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPEEVLTDELLERV 236

                         250
                  ....*....|....*....
gi 1560390145 240 YEIEAQIIELPETNKPVVL 258
Cdd:COG4559   237 YGADLRVLAHPEGGCPQVL 255
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
25-260 1.10e-66

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 208.10  E-value: 1.10e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPLGMTVEEVVSYG 104
Cdd:PRK10575   30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPAAEGMTVRELVAIG 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 105 RYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHL 184
Cdd:PRK10575  110 RYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLAL 189

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 185 LKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQIIELPETNKPVVLSY 260
Cdd:PRK10575  190 VHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRGETLEQIYGIPMGILPHPAGAAPVSFVY 265
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 7-232 1.55e-64

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 201.41  E-value: 1.55e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLN-KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:COG1122     1 IELENLSFSYPGgTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRKVGLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPL-GMTVEEVVSYGryPYQkffSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADI 163
Cdd:COG1122    81 FQNPDDQLfAPTVEEDVAFG--PEN---LGLPREEIRErVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEV 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 164 LILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:COG1122   156 LVLDEPTAGLDPRGRRELLELLKRLNK-EGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFS 223
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 8-214 2.82e-64

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 200.07  E-value: 2.82e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   8 EAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseistYSPKMLAQKIALLAQ 87
Cdd:cd03235     1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFG-----KPLEKERKRIGYVPQ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 SSEHPLGM--TVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:cd03235    76 RRSIDRDFpiSVRDVVLMGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLL 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKEInHIKQTTILMSIHDINHASRFSDYLI 214
Cdd:cd03235   156 LDEPFAGVDPKTQEDIYELLREL-RREGMTILVVTHDLGLVLEYFDRVL 203
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 18-240 1.34e-56

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 181.61  E-value: 1.34e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQ---KIALLAQssEHPL- 93
Cdd:cd03256    13 GKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQlrrQIGMIFQ--QFNLi 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 -GMTVEEVVSYGRYPYQKFFSGL-----NEEDLHAIQwALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILD 167
Cdd:cd03256    91 eRLSVLENVLSGRLGRRSTWRSLfglfpKEEKQRALA-ALERVGLLDKAYQRADQLSGGQQQRVAIARALMQQPKLILAD 169

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 168 EPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEvITTSWMREIY 240
Cdd:cd03256   170 EPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAE-LTDEVLDEIY 241
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
7-231 5.72e-56

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 179.87  E-value: 5.72e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLaQKIALLA 86
Cdd:COG1131     1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVR-RRIGYVP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYgrypYQKFFsGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:COG1131    80 QEPALYPDLTVRENLRF----FARLY-GLPRKEARErIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLI 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:COG1131   155 LDEPTSGLDPEARRELWELLRELAA-EGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELK 219
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
 5-245 8.28e-56

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 179.87  E-value: 8.28e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   5 TTIEAVDITTGYLN-KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQ--- 80
Cdd:COG3638     1 PMLELRNLSKRYPGgTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRRlrr 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 KIALLAQssEHPL--GMTVEEVVSYGRYPY----QKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIA 154
Cdd:COG3638    81 RIGMIFQ--QFNLvpRLSVLTNVLAGRLGRtstwRSLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAIA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 155 MALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEViTTS 234
Cdd:COG3638   159 RALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAEL-TDA 237

                         250
                  ....*....|.
gi 1560390145 235 WMREIYEIEAQ 245
Cdd:COG3638   238 VLREIYGGEAE 248
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 8-220 5.22e-54

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 173.81  E-value: 5.22e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   8 EAVDITTGY--LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:cd03225     1 ELKNLSFSYpdGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGLV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPL-GMTVEEVVSYGRYPYqkffsGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADI 163
Cdd:cd03225    81 FQNPDDQFfGPTVEEEVAFGLENL-----GLPEEEIEErVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDI 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 164 LILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQ 220
Cdd:cd03225   156 LLLDEPTAGLDPAGRRELLELLKKLKA-EGKTIIIVTHDLDLLLELADRVIVLEDGK 211
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 6-271 6.98e-50

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 168.87  E-value: 6.98e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:PRK09536    3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAASRRVASV 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:PRK09536   83 PQDTSLSFEFDVRQVVEMGRTPHRSRFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQATPVLL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKEINHIKQTTIlMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQ 245
Cdd:PRK09536  163 LDEPTASLDINHQVRTLELVRRLVDDGKTAV-AAIHDLDLAARYCDELVLLADGRVRAAGPPADVLTADTLRAAFDARTA 241

                         250       260
                  ....*....|....*....|....*.
gi 1560390145 246 IIELPETNKPVVLSYDLINDRKEDEQ 271
Cdd:PRK09536  242 VGTDPATGAPTVTPLPDPDRTEAAAD 267
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 7-230 2.87e-49

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 162.35  E-value: 2.87e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK-----EGKIIVDGSEIST--YSPKMLA 79
Cdd:cd03260     1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIpgapdEGEVLLDGKDIYDldVDVLELR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  80 QKIALLAQSSeHPLGMTVEEVVSYGrypyQKFFSGLNEEDLHAI-QWALEATQLTKLKERELS--SLSGGQAQRVWIAMA 156
Cdd:cd03260    81 RRVGMVFQKP-NPFPGSIYDNVAYG----LRLHGIKLKEELDERvEEALRKAALWDEVKDRLHalGLSGGQQQRLCLARA 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 157 LAQEADILILDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:cd03260   156 LANEPEVLLLDEPTSALDPISTAKIEELIAELK--KEYTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 17-252 2.98e-49

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 163.78  E-value: 2.98e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  17 LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA---QKIALLAQSSEHPL 93
Cdd:TIGR04521  16 FEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKdlrKKVGLVFQFPEHQL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 -GMTVEEVVSYGryPyQKFfsGLNEEDLHA-IQWALEATQLT-KLKERELSSLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:TIGR04521  96 fEETVYKDIAFG--P-KNL--GLSEEEAEErVKEALELVGLDeEYLERSPFELSGGQMRRVAIAGVLAMEPEVLILDEPT 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 171 TFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVittswMREIYEIEAQIIELP 250
Cdd:TIGR04521 171 AGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREV-----FSDVDELEKIGLDVP 245


                  ..
gi 1560390145 251 ET 252
Cdd:TIGR04521 246 EI 247
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 1-232 8.96e-49

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 168.54  E-value: 8.96e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK---EGKIIVDGSEISTYSPKM 77
Cdd:COG1123     1 MTPLLEVRDLSVRYPGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  78 LAQKIALLAQSSEHPL-GMTVEEVVSYGRypyqkFFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAM 155
Cdd:COG1123    81 RGRRIGMVFQDPMTQLnPVTVGDQIAEAL-----ENLGLSRAEARArVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAM 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 156 ALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:COG1123   156 ALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILA 232
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
 18-240 1.05e-48

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 161.31  E-value: 1.05e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK---MLAQKIALLAQssEHPL- 93
Cdd:TIGR02315  14 GKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKklrKLRRRIGMIFQ--HYNLi 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 -GMTVEEVVSYGRYPYQKFFSGL-----NEEDLHAIQwALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILD 167
Cdd:TIGR02315  92 eRLTVLENVLHGRLGYKPTWRSLlgrfsEEDKERALS-ALERVGLADKAYQRADQLSGGQQQRVAIARALAQQPDLILAD 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 168 EPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEvITTSWMREIY 240
Cdd:TIGR02315 171 EPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSE-LDDEVLRHIY 242
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 7-232 2.44e-48

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 167.39  E-value: 2.44e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNK-----QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP---KML 78
Cdd:COG1123   261 LEVRNLSKRYPVRgkggvRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRrslREL 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  79 AQKIALLAQSSEHPL--GMTVEEVVSYGrypyQKFFSGLNEEDLHA-IQWALEATQL-TKLKERELSSLSGGQAQRVWIA 154
Cdd:COG1123   341 RRRVQMVFQDPYSSLnpRMTVGDIIAEP----LRLHGLLSRAERRErVAELLERVGLpPDLADRYPHELSGGQRQRVAIA 416

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 155 MALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:COG1123   417 RALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFA 494
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 2-225 3.88e-48

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 159.21  E-value: 3.88e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   2 KNLTtieaVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA-- 79
Cdd:cd03257     5 KNLS----VSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKir 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  80 -QKIALLAQ---SSEHPLgMTVEEVVsygRYPYQKFFSGLNEEdlhaiqwALEATQLTKLKERELSS---------LSGG 146
Cdd:cd03257    81 rKEIQMVFQdpmSSLNPR-MTIGEQI---AEPLRIHGKLSKKE-------ARKEAVLLLLVGVGLPEevlnrypheLSGG 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 147 QAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03257   150 QRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 7-252 7.13e-48

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 159.90  E-value: 7.13e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLN--KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseISTYSPKML---AQK 81
Cdd:TIGR04520   1 IEVENVSFSYPEseKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDG--LDTLDEENLweiRKK 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IALLAQSSEHPL-GMTVEEVVSYG----RYPYqkffsglnEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMA 156
Cdd:TIGR04520  79 VGMVFQNPDNQFvGATVEDDVAFGlenlGVPR--------EEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGV 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 157 LAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVIT-TSW 235
Cdd:TIGR04520 151 LAMRPDIIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAVL-ADRVIVMNKGKIVAEGTPREIFSqVEL 229

                         250       260
                  ....*....|....*....|....*...
gi 1560390145 236 MREI-----------YEIEAQIIELPET 252
Cdd:TIGR04520 230 LKEIgldvpfitelaKALKKRGIPLPPD 257
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
 32-249 4.02e-47

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 157.31  E-value: 4.02e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  32 GKVTSLIGPNGSGKSTLLKSFTRLLPvKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPLGMTVEEVVSYGRYPyqkf 111
Cdd:COG4138    22 GELIHLIGPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDWSAAELARHRAYLSQQQSPPFAMPVFQYLALHQPA---- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 112 fSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQ-------EADILILDEPTTFLDPAHQLEILHL 184
Cdd:COG4138    97 -GASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwptinpEGQLLLLDEPMNSLDVAQQAALDRL 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 185 LKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQIIEL 249
Cdd:COG4138   176 LRELCQ-QGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVMTPENLSEVFGVKFRRLEV 239
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
15-208 1.98e-45

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 151.23  E-value: 1.98e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  15 GYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEistyspkmlaqKIALLAQSSEHP-- 92
Cdd:NF040873    1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGA-----------RVAYVPQRSEVPds 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  93 LGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:NF040873   70 LPLTVRDLVAMGRWARRGLWRRLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTG 149

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1560390145 173 LDPAHQLEILHLLKEInHIKQTTILMSIHDINHASR 208
Cdd:NF040873  150 LDAESRERIIALLAEE-HARGATVVVVTHDLELVRR 184
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 7-230 3.35e-45

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 152.26  E-value: 3.35e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDIT----TGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKI 82
Cdd:COG1124     2 LEVRNLSvsygQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRRRV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  83 ALLAQ---SSEHPLgMTVEEVVSYgryPYQKFFSGLNEEDLHAiqwALEATQLTK-LKERELSSLSGGQAQRVWIAMALA 158
Cdd:COG1124    82 QMVFQdpyASLHPR-HTVDRILAE---PLRIHGLPDREERIAE---LLEQVGLPPsFLDRYPHQLSGGQRQRVAIARALI 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 159 QEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:COG1124   155 LEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADL 226
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 7-233 2.62e-44

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 149.74  E-value: 2.62e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK---MLAQKIA 83
Cdd:COG1127     6 IEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKelyELRRRIG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  84 LLAQ-----SSehplgMTVEEVVSYG-RYpyqkfFSGLNEEDLHAI-QWALEATQLTKLKERELSSLSGGQAQRVWIAMA 156
Cdd:COG1127    86 MLFQggalfDS-----LTVFENVAFPlRE-----HTDLSEAEIRELvLEKLELVGLPGAADKMPSELSGGMRKRVALARA 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 157 LAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITT 233
Cdd:COG1127   156 LALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLAS 232
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 7-230 6.05e-44

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 148.35  E-value: 6.05e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQK-IALL 85
Cdd:cd03224     1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAgIGYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPLGMTVEEVVSYGRYPYQKffsglneedlHAIQWALEA--TQLTKLKERELS---SLSGGQAQRVWIAMALAQE 160
Cdd:cd03224    81 PEGRRIFPELTVEENLLLGAYARRR----------AKRKARLERvyELFPRLKERRKQlagTLSGGEQQMLAIARALMSR 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:cd03224   151 PKLLLLDEPSEGLAPKIVEEIFEAIRELRD-EGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAEL 219
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 7-242 6.89e-44

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 148.85  E-value: 6.89e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGsEISTYSPKMLAQKIALLA 86
Cdd:COG4555     2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDG-EDVRKEPREARRQIGVLP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEvvsygrypYQKFFSGLN----EEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEAD 162
Cdd:COG4555    81 DERGLYDRLTVRE--------NIRYFAELYglfdEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPK 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 163 ILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEI 242
Cdd:COG4555   153 VLLLDEPTNGLDVMARRLLREILRALKK-EGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEENLEDA 231
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
7-221 1.38e-43

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 146.88  E-value: 1.38e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA 86
Cdd:COG4619     1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEWRRQVAYVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSeHPLGMTVEEVVsygRYPYQKFFSGLNEEDLHAiqwALEATQLTK-LKERELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:COG4619    81 QEP-ALWGGTVRDNL---PFPFQLRERKFDRERALE---LLERLGLPPdILDKPVERLSGGERQRLALIRALLLQPDVLL 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQI 221
Cdd:COG4619   154 LDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
26-229 4.06e-43

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 146.44  E-value: 4.06e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPkmlAQ-KIALLAQssEHPL--GMTVEEVVS 102
Cdd:COG3840    19 DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPP---AErPVSMLFQ--ENNLfpHLTVAQNIG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 103 YGRYPYQKffsgLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEIL 182
Cdd:COG3840    94 LGLRPGLK----LTAEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKRPILLLDEPFSALDPALRQEML 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1560390145 183 HLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:COG3840   170 DLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAA 216
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 7-221 1.47e-42

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 144.55  E-value: 1.47e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDIT----TGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA--- 79
Cdd:cd03255     1 IELKNLSktygGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAafr 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  80 -QKIALLAQSseHPL--GMTVEEVVSYGrypyqKFFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAM 155
Cdd:cd03255    81 rRHIGFVFQS--FNLlpDLTALENVELP-----LLLAGVPKKERRErAEELLERVGLGDRLNHYPSELSGGQQQRVAIAR 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 156 ALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFsDYLIGMKAGQI 221
Cdd:cd03255   154 ALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAEYA-DRIIELRDGKI 218
hmuV PRK13547
heme ABC transporter ATP-binding protein;
21-258 1.52e-41

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 143.81  E-value: 1.52e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK--------EGKIIVDGSEISTYSPKMLAQKIALLAQSSEHP 92
Cdd:PRK13547   16 ILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNGEPLAAIDAPRLARLRAVLPQAAQPA 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  93 LGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQ---------EADI 163
Cdd:PRK13547   96 FAFSAREIVLLGRYPHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLAQlwpphdaaqPPRY 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 164 LILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIE 243
Cdd:PRK13547  176 LLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPADVLTPAHIARCYGFA 255

                         250
                  ....*....|....*
gi 1560390145 244 AQIIELPETNKPVVL 258
Cdd:PRK13547  256 VRLVDAGDGVPPVIV 270
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 7-233 2.88e-41

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 141.87  E-value: 2.88e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK---MLAQKIA 83
Cdd:cd03261     1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAelyRLRRRMG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  84 LLAQSSEHPLGMTVEEVVSYGRYPYqkffSGLNEEDLHAIqwALEATQLTKLKEREL---SSLSGGQAQRVWIAMALAQE 160
Cdd:cd03261    81 MLFQSGALFDSLTVFENVAFPLREH----TRLSEEEIREI--VLEKLEAVGLRGAEDlypAELSGGMKKRVALARALALD 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITT 233
Cdd:cd03261   155 PELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRAS 227
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 6-229 2.35e-40

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 146.44  E-value: 2.35e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLN-KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:COG4988   336 SIELEDVSFSYPGgRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRRQIAW 415

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSeHPLGMTVEEVVSYGRypyqkffsglNEEDLHAIQWALEATQL------------TKLKERElSSLSGGQAQRVW 152
Cdd:COG4988   416 VPQNP-YLFAGTIRENLRLGR----------PDASDEELEAALEAAGLdefvaalpdgldTPLGEGG-RGLSGGQAQRLA 483

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDInHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:COG4988   484 LARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLA--KGRTVILITHRL-ALLAQADRILVLDDGRIVEQGTHEE 557
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 26-232 4.50e-40

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 138.72  E-value: 4.50e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA--------QKIALLAqssehplGMTV 97
Cdd:cd03219    20 SFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIArlgigrtfQIPRLFP-------ELTV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  98 EEVV------SYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:cd03219    93 LENVmvaaqaRTGSGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAA 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 172 FLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:cd03219   173 GLNPEETEELAELIRELRE-RGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRN 232
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 6-234 6.65e-40

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 145.29  E-value: 6.65e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLN--KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIA 83
Cdd:COG4987   333 SLELEDVSFRYPGagRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRRIA 412

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  84 LLAQSSeHPLGMTVEEVVSYGRypyqkffSGLNEEDLHAiqwALEATQLTKLKEREL-----------SSLSGGQAQRVW 152
Cdd:COG4987   413 VVPQRP-HLFDTTLRENLRLAR-------PDATDEELWA---ALERVGLGDWLAALPdgldtwlgeggRRLSGGERRRLA 481

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAHQLEILHLLKEinHIKQTTILMSIHDINHASRFsDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:COG4987   482 LARALLRDAPILLLDEPTEGLDAATEQALLADLLE--ALAGRTVLLITHRLAGLERM-DRILVLEDGRIVEQGTHEELLA 558


                  ..
gi 1560390145 233 TS 234
Cdd:COG4987   559 QN 560
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 7-221 7.32e-40

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 136.37  E-value: 7.32e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLaQKIALLA 86
Cdd:cd03230     1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVK-RRIGYLP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYgrypyqkffsglneedlhaiqwaleatqltklkerelsslSGGQAQRVWIAMALAQEADILIL 166
Cdd:cd03230    80 EEPSLYENLTVRENLKL----------------------------------------SGGMKQRLALAQALLHDPELLIL 119

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQI 221
Cdd:cd03230   120 DEPTSGLDPESRREFWELLRELKK-EGKTILLSSHILEEAERLCDRVAILNNGRI 173
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 8-220 9.90e-40

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 135.45  E-value: 9.90e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   8 EAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQ 87
Cdd:cd00267     1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIGYVPQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 ssehplgmtveevvsygrypyqkffsglneedlhaiqwaleatqltklkerelssLSGGQAQRVWIAMALAQEADILILD 167
Cdd:cd00267    81 -------------------------------------------------------LSGGQRQRVALARALLLNPDLLLLD 105

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 168 EPTTFLDPAHQLEILHLLKEInHIKQTTILMSIHDINHASRFSDYLIGMKAGQ 220
Cdd:cd00267   106 EPTSGLDPASRERLLELLREL-AEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 7-233 5.66e-39

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 136.28  E-value: 5.66e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLN-KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:cd03295     1 IEFENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRRKIGYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSsehpLG----MTVEE----VVSYGRYPYQKffsglneedlhAIQWALEATQLTKLKEREL-----SSLSGGQAQRVW 152
Cdd:cd03295    81 IQQ----IGlfphMTVEEnialVPKLLKWPKEK-----------IRERADELLALVGLDPAEFadrypHELSGGQQQRVG 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 153 IAMALAQEADILILDEPTTFLDP----AHQLEILHLLKEINHikqtTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPD 228
Cdd:cd03295   146 VARALAADPPLLLMDEPFGALDPitrdQLQEEFKRLQQELGK----TIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPD 221


                  ....*
gi 1560390145 229 EVITT 233
Cdd:cd03295   222 EILRS 226
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 7-220 5.34e-38

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 131.54  E-value: 5.34e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA--QKIAL 84
Cdd:cd03229     1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPlrRRIGM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHPLGMTVEEVVSYGrypyqkffsglneedlhaiqwaleatqltklkerelssLSGGQAQRVWIAMALAQEADIL 164
Cdd:cd03229    81 VFQDFALFPHLTVLENIALG--------------------------------------LSGGQQQRVALARALAMDPDVL 122

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQ 220
Cdd:cd03229   123 LLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 11-240 9.18e-38

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 132.80  E-value: 9.18e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  11 DITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQK-IALLAQss 89
Cdd:COG0410     8 NLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLgIGYVPE-- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  90 ehplG------MTVEE---VVSYGRypyqkffsglneEDLHAIQWALEA--TQLTKLKERELS---SLSGGQAQRVWIAM 155
Cdd:COG0410    86 ----GrrifpsLTVEEnllLGAYAR------------RDRAEVRADLERvyELFPRLKERRRQragTLSGGEQQMLAIGR 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 156 ALAQEADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSW 235
Cdd:COG0410   150 ALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNR-EGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAELLADPE 228


                  ....*
gi 1560390145 236 MREIY 240
Cdd:COG0410   229 VREAY 233
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 7-225 1.01e-37

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 131.93  E-value: 1.01e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGkVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYsPKMLAQKIALLA 86
Cdd:cd03264     1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQ-PQKLRRRIGYLP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYgrypyQKFFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:cd03264    79 QEFGVYPNFTVREFLDY-----IAWLKGIPSKEVKArVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILI 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03264   154 VDEPTAGLDPEERIRFRNLLSELG--EDRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
cbiO TIGR01166
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...
 20-206 1.77e-37

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130234 [Multi-domain]  Cd Length: 190  Bit Score: 130.62  E-value: 1.77e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  20 QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStYSPKMLA---QKIALLAQSSEHPL-GM 95
Cdd:TIGR01166   6 EVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLD-YSRKGLLerrQRVGLVFQDPDDQLfAA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 TVEEVVSYGryPYQKffsGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:TIGR01166  85 DVDQDVAFG--PLNL---GLSEAEVERrVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLD 159

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1560390145 175 PAHQLEILHLLKEINHiKQTTILMSIHDINHA 206
Cdd:TIGR01166 160 PAGREQMLAILRRLRA-EGMTVVISTHDVDLA 190
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 20-232 1.88e-37

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 134.41  E-value: 1.88e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  20 QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP---VKEGKIIVDGSEISTYSPKMLAQ----KIALLAQ---SS 89
Cdd:COG0444    19 KAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPppgITSGEILFDGEDLLKLSEKELRKirgrEIQMIFQdpmTS 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  90 EHPLgMTVEEVVsygRYPYQKFFsGLNEEDLH--AIQwALEATQLTKLKEReLSS----LSGGQAQRVWIAMALAQEADI 163
Cdd:COG0444    99 LNPV-MTVGDQI---AEPLRIHG-GLSKAEARerAIE-LLERVGLPDPERR-LDRypheLSGGMRQRVMIARALALEPKL 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 164 LILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:COG0444   172 LIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFE 240
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 7-231 2.56e-37

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 139.20  E-value: 2.56e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGY--LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:COG2274   474 IELENVSFRYpgDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLRRQIGV 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSeHPLGMTVEEVVSYGRypyqkffSGLNEEDlhaIQWALEATQL------------TKLKERElSSLSGGQAQRVW 152
Cdd:COG2274   554 VLQDV-FLFSGTIRENITLGD-------PDATDEE---IIEAARLAGLhdfiealpmgydTVVGEGG-SNLSGGQRQRLA 621

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSiHD---INHAsrfsDYLIGMKAGQIVVQGTPDE 229
Cdd:COG2274   622 IARALLRNPRILILDEATSALDAETEAIILENLRRLLK-GRTVIIIA-HRlstIRLA----DRIIVLDKGRIVEDGTHEE 695


                  ..
gi 1560390145 230 VI 231
Cdd:COG2274   696 LL 697
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-222 2.58e-37

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 131.32  E-value: 2.58e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLttIEAVDIT----TGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK 76
Cdd:COG1136     1 MSPL--LELRNLTksygTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSER 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  77 MLA----QKIALLAQSseHPL--GMTVEEVVSYGRYpyqkfFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQ 149
Cdd:COG1136    79 ELArlrrRHIGFVFQF--FNLlpELTALENVALPLL-----LAGVSRKERRErARELLERVGLGDRLDHRPSQLSGGQQQ 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 150 RVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFsDYLIGMKAGQIV 222
Cdd:COG1136   152 RVAIARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAARA-DRVIRLRDGRIV 223
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 20-230 3.59e-37

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 131.70  E-value: 3.59e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  20 QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA--------QKIALLAqsseh 91
Cdd:COG0411    18 VAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIArlgiartfQNPRLFP----- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  92 plGMTVEEVVSYGRYPYQK--FFSGL--------NEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:COG0411    93 --ELTVLENVLVAAHARLGrgLLAALlrlprarrEEREARErAEELLERVGLADRADEPAGNLSYGQQRRLEIARALATE 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMsI-HDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:COG0411   171 PKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILL-IeHDMDLVMGLADRIVVLDFGRVIAEGTPAEV 240
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 7-222 1.12e-36

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 129.18  E-value: 1.12e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-----MLAQK 81
Cdd:cd03259     1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPErrnigMVFQD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IALLAqsseHplgMTVEEVVSYGRYPyqkffSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:cd03259    81 YALFP----H---LTVAENIAFGLKL-----RGVPKAEIRArVRELLELVGLEGLLNRYPHELSGGQQQRVALARALARE 148

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIV 222
Cdd:cd03259   149 PSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIV 210
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 7-230 1.81e-36

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 132.53  E-value: 1.81e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLksftRLL----PVKEGKIIVDGSEISTYSP-----KM 77
Cdd:COG3842     6 LELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLL----RMIagfeTPDSGRILLDGRDVTGLPPekrnvGM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  78 LAQKIALLAqsseHplgMTVEEVVSYG-RypyqkfFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAM 155
Cdd:COG3842    82 VFQDYALFP----H---LTVAENVAFGlR------MRGVPKAEIRArVAELLELVGLEGLADRYPHQLSGGQQQRVALAR 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 156 ALAQEADILILDEPTTFLDPAH----QLEILHLLKEINhikqTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:COG3842   149 ALAPEPRVLLLDEPLSALDAKLreemREELRRLQRELG----ITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEI 223
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 7-233 2.02e-36

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 129.77  E-value: 2.02e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTR---LLP-VK-EGKIIVDGSEIstYSPKM---- 77
Cdd:COG1117    12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRmndLIPgARvEGEILLDGEDI--YDPDVdvve 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  78 LAQKIALLAQSSeHPLGMTVEEVVSYG-RYpyqkffSGL-NEEDLHAI-QWALEATQL-----TKLKERELsSLSGGQAQ 149
Cdd:COG1117    90 LRRRVGMVFQKP-NPFPKSIYDNVAYGlRL------HGIkSKSELDEIvEESLRKAALwdevkDRLKKSAL-GLSGGQQQ 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 150 RVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:COG1117   162 RLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELK--KDYTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQ 239


                  ....
gi 1560390145 230 VITT 233
Cdd:COG1117   240 IFTN 243
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 7-232 3.25e-36

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 129.81  E-value: 3.25e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLN-KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStYSPKMLA---QKI 82
Cdd:PRK13639    2 LETRDLKYSYPDgTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIK-YDKKSLLevrKTV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  83 ALLAQSSEHPL-GMTVEEVVSYGryPYQKffsGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:PRK13639   81 GIVFQNPDDQLfAPTVEEDVAFG--PLNL---GLSKEEVEKrVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMK 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:PRK13639  156 PEIIVLDEPTSGLDPMGASQIMKLLYDLNK-EGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFS 226
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 7-227 3.29e-36

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 129.86  E-value: 3.29e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLN-KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:PRK13647    5 IEVEDLHFRYKDgTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVGLV 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPL-GMTVEEVVSYGryPYQKFFSGlnEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:PRK13647   85 FQDPDDQVfSSTVWDDVAFG--PVNMGLDK--DEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVI 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTP 227
Cdd:PRK13647  161 VLDEPMAYLDPRGQETLMEILDRLHN-QGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDK 222
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 26-254 3.35e-36

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 130.14  E-value: 3.35e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP----KMLAQKIALLAQSSEHPL-GMTVEEV 100
Cdd:PRK13634   27 NVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKnkklKPLRKKVGIVFQFPEHQLfEETVEKD 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYGryPyQKFfsGLNEEDlhAIQWALEATQLTKLKERELS----SLSGGQAQRVWIAMALAQEADILILDEPTTFLDPA 176
Cdd:PRK13634  107 ICFG--P-MNF--GVSEED--AKQKAREMIELVGLPEELLArspfELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPK 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 177 HQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVittswMREIYEIEAQIIELPETNK 254
Cdd:PRK13634  180 GRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREI-----FADPDELEAIGLDLPETVK 252
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 6-230 4.29e-36

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 131.42  E-value: 4.29e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPkmlAQ--KIA 83
Cdd:COG1118     2 SIEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFTNLP---PRerRVG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  84 LLAQsseHPL---GMTVEEVVSYG---RYPyqkffsglNEEDLHAI--QWaLEATQLTKLKERELSSLSGGQAQRVWIAM 155
Cdd:COG1118    79 FVFQ---HYAlfpHMTVAENIAFGlrvRPP--------SKAEIRARveEL-LELVQLEGLADRYPSQLSGGQRQRVALAR 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 156 ALAQEADILILDEPttF--LDpAH---QLEIL--HLLKEINHikqTTILMSiHDINHASRFSDYLIGMKAGQIVVQGTPD 228
Cdd:COG1118   147 ALAVEPEVLLLDEP--FgaLD-AKvrkELRRWlrRLHDELGG---TTVFVT-HDQEEALELADRVVVMNQGRIEQVGTPD 219


                  ..
gi 1560390145 229 EV 230
Cdd:COG1118   220 EV 221
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 32-249 8.41e-36

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 128.13  E-value: 8.41e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  32 GKVTSLIGPNGSGKSTLLKSFTRLLPvKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPLGMTVeevvsygrYPYQKF 111
Cdd:PRK03695   22 GEILHLVGPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEAWSAAELARHRAYLSQQQTPPFAMPV--------FQYLTL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 112 F--SGLNEEDL-HAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQ-------EADILILDEPTTFLDPAHQLEI 181
Cdd:PRK03695   93 HqpDKTRTEAVaSALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQvwpdinpAGQLLLLDEPMNSLDVAQQAAL 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 182 LHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQIIEL 249
Cdd:PRK03695  173 DRLLSELCQ-QGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDEVLTPENLAQVFGVNFRRLDV 239
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 7-232 1.17e-35

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 127.42  E-value: 1.17e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIsTYSPKMLA---QKIA 83
Cdd:COG1126     2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDL-TDSKKDINklrRKVG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  84 LLAQSSE---HplgMTVEEVVSYGrypyQKFFSGLNEEDLHAIqwALEatQLTK--LKEREL---SSLSGGQAQRVWIAM 155
Cdd:COG1126    81 MVFQQFNlfpH---LTVLENVTLA----PIKVKKMSKAEAEER--AME--LLERvgLADKADaypAQLSGGQQQRVAIAR 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 156 ALAQEADILILDEPTTFLDPahQL--EILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:COG1126   150 ALAMEPKVMLFDEPTSALDP--ELvgEVLDVMRDLAK-EGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFE 225
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 7-232 1.29e-35

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 128.18  E-value: 1.29e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLN--KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:PRK13632    8 IKVENVSFSYPNseNNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIRKKIGI 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHP-LGMTVEEVVSYG----RYPYQKFFSGLNEedlhaiqwALEATQLTKLKERELSSLSGGQAQRVWIAMALAQ 159
Cdd:PRK13632   88 IFQNPDNQfIGATVEDDIAFGlenkKVPPKKMKDIIDD--------LAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLAL 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 160 EADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:PRK13632  160 NPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAIL-ADKVIVFSEGKLIAQGKPKEILN 231
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
1-230 1.42e-35

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 128.21  E-value: 1.42e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQ 80
Cdd:PRK13635    2 KEEIIRVEHISFRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 KIALLAQSSEHP-LGMTVEEVVSYG-------RypyqkffsglnEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVW 152
Cdd:PRK13635   82 QVGMVFQNPDNQfVGATVQDDVAFGlenigvpR-----------EEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVA 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK13635  151 IAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEI 227
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
18-245 1.73e-35

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 133.37  E-value: 1.73e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQssEHPL-GMT 96
Cdd:COG1132   352 DRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQIGVVPQ--DTFLfSGT 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  97 VEEVVSYGRypyqkffsglNEEDLHAIQWALEATQL------------TKLKERElSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:COG1132   430 IRENIRYGR----------PDATDEEVEEAAKAAQAhefiealpdgydTVVGERG-VNLSGGQRQRIAIARALLKDPPIL 498

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEInhIKQTTILMsihdINHasRFS-----DYLIGMKAGQIVVQGTPDEVITTS-WMRE 238
Cdd:COG1132   499 ILDEATSALDTETEALIQEALERL--MKGRTTIV----IAH--RLStirnaDRILVLDDGRIVEQGTHEELLARGgLYAR 570


                  ....*..
gi 1560390145 239 IYEIEAQ 245
Cdd:COG1132   571 LYRLQFG 577
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 25-171 2.36e-35

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 123.91  E-value: 2.36e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPLGMTVEEVVSYG 104
Cdd:pfam00005   4 VSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDPQLFPRLTVRENLRLG 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 105 RYPYQKFFSGLNEEdlhaIQWALEATQLTKLKEREL----SSLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:pfam00005  84 LLLKGLSKREKDAR----AEEALEKLGLGDLADRPVgerpGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
cbiO PRK13637
energy-coupling factor transporter ATPase;
19-230 7.71e-35

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 126.70  E-value: 7.71e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKM--LAQKIALLAQSSEHPL-GM 95
Cdd:PRK13637   20 KKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKLsdIRKKVGLVFQYPEYQLfEE 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 TVEEVVSYGryPYQKffsGLNEEDLHA-IQWALEATQLT--KLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:PRK13637  100 TIEKDIAFG--PINL---GLSEEEIENrVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAG 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 173 LDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK13637  175 LDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREV 232
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 18-220 1.45e-34

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 122.49  E-value: 1.45e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSeHPLGMTV 97
Cdd:cd03228    14 PKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKNIAYVPQDP-FLFSGTI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  98 EEVVsygrypyqkffsglneedlhaiqwaleatqltklkerelssLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAH 177
Cdd:cd03228    93 RENI-----------------------------------------LSGGQRQRIAIARALLRDPPILILDEATSALDPET 131

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1560390145 178 QLEILHLLKEInhIKQTTILMSIHDINHASRFsDYLIGMKAGQ 220
Cdd:cd03228   132 EALILEALRAL--AKGKTVIVIAHRLSTIRDA-DRIIVLDDGR 171
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 7-221 1.92e-34

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 123.41  E-value: 1.92e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKM--LAQKIAL 84
Cdd:cd03262     1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNIneLRQKVGM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSS---EHplgMTVEEVVSYGrypyQKFFSGLNEEDlhAIQWALEATQLTKLKERELS---SLSGGQAQRVWIAMALA 158
Cdd:cd03262    81 VFQQFnlfPH---LTVLENITLA----PIKVKGMSKAE--AEERALELLEKVGLADKADAypaQLSGGQQQRVAIARALA 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 159 QEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQI 221
Cdd:cd03262   152 MNPKVMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVT-HEMGFAREVADRVIFMDDGRI 213
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 19-229 2.25e-34

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 123.38  E-value: 2.25e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTySPKMLAQKIALLAQSSEHPLGMTVE 98
Cdd:cd03263    15 KPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRT-DRKAARQSLGYCPQFDALFDELTVR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  99 EVVsygrypyqKFFS---GLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:cd03263    94 EHL--------RFYArlkGLPKSEIKEeVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLD 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 175 PAHQLEILHLLKEInhIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:cd03263   166 PASRRAIWDLILEV--RKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQE 218
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 7-232 4.22e-34

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 123.87  E-value: 4.22e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLL-----PVKEGKIIVDGSEISTYSPKMLAQK 81
Cdd:PRK14247    4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLIelypeARVSGEVYLDGQDIFKMDVIELRRR 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IALLAQSSEHPLGMTVEEVVSYGryPYQKFFSGLNEEDLHAIQWALEATQL-TKLKER---ELSSLSGGQAQRVWIAMAL 157
Cdd:PRK14247   84 VQMVFQIPNPIPNLSIFENVALG--LKLNRLVKSKKELQERVRWALEKAQLwDEVKDRldaPAGKLSGGQQQRLCIARAL 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 158 AQEADILILDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:PRK14247  162 AFQPEVLLADEPTANLDPENTAKIESLFLELK--KDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFT 234
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 8-222 5.44e-34

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 121.98  E-value: 5.44e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   8 EAVDITTGY-LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStysPKMLAQKIALLA 86
Cdd:cd03226     1 RIENISFSYkKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIK---AKERRKSIGYVM 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGM-TVEEVVSYGrypyqkffSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:cd03226    78 QDVDYQLFTdSVREELLLG--------LKELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLI 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKEINHIKqTTILMSIHDINHASRFSDYLIGMKAGQIV 222
Cdd:cd03226   150 FDEPTSGLDYKNMERVGELIRELAAQG-KAVIVITHDYEFLAKVCDRVLLLANGAIV 205
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 25-230 1.07e-33

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 123.42  E-value: 1.07e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStYSPK---MLAQKIALLAQSSEHPL-GMTVEEV 100
Cdd:PRK13636   25 ININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPID-YSRKglmKLRESVGMVFQDPDNQLfSASVYQD 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYGRYPYQkffsgLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQL 179
Cdd:PRK13636  104 VSFGAVNLK-----LPEDEVRKrVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVS 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 180 EILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK13636  179 EIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEV 229
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 2-232 1.52e-33

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 127.49  E-value: 1.52e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   2 KNLTtieaVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKS-TLLkSFTRLLP----VKEGKIIVDGSEISTYSPK 76
Cdd:COG4172    10 EDLS----VAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvTAL-SILRLLPdpaaHPSGSILFDGQDLLGLSER 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  77 MLAQ----KIALLAQ---SSEHPLgMTVE----EVVSYGRypyqkffsGLNEEDlhAIQWALEATQLTKLK--ERELSS- 142
Cdd:COG4172    85 ELRRirgnRIAMIFQepmTSLNPL-HTIGkqiaEVLRLHR--------GLSGAA--ARARALELLERVGIPdpERRLDAy 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 143 ---LSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAG 219
Cdd:COG4172   154 phqLSGGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQG 233

                         250
                  ....*....|...
gi 1560390145 220 QIVVQGTPDEVIT 232
Cdd:COG4172   234 EIVEQGPTAELFA 246
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 7-229 3.84e-33

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 120.55  E-value: 3.84e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTySPKMLAQKIALLA 86
Cdd:cd03265     1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVR-EPREVRRRIGIVF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMT-VEEVVSYGR-YPYQkffsglNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:cd03265    80 QDLSVDDELTgWENLYIHARlYGVP------GAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVL 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:cd03265   154 FLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEE 218
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
7-234 4.19e-33

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 120.97  E-value: 4.19e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseISTYSPK---------- 76
Cdd:PRK09493    2 IEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDG--LKVNDPKvderlirqea 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  77 -MLAQKIALLAQssehplgMTVEEVVSYGryPYQkfFSGLNEEDLHAIQWALeatqLTK--LKERE---LSSLSGGQAQR 150
Cdd:PRK09493   80 gMVFQQFYLFPH-------LTALENVMFG--PLR--VRGASKEEAEKQAREL----LAKvgLAERAhhyPSELSGGQQQR 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 151 VWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK09493  145 VAIARALAVKPKLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVT-HEIGFAEKVASRLIFIDKGRIAEDGDPQVL 223


                  ....
gi 1560390145 231 ITTS 234
Cdd:PRK09493  224 IKNP 227
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 6-230 4.80e-33

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 122.14  E-value: 4.80e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIsTYSPKmlaQKIALL 85
Cdd:COG4152     1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPL-DPEDR---RRIGYL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 aqssehP------LGMTVEEVVSY-GRypyqkfFSGLNEEDLH--AIQWaLEATQLTKLKERELSSLSGGQAQRVWIAMA 156
Cdd:COG4152    77 ------PeerglyPKMKVGEQLVYlAR------LKGLSKAEAKrrADEW-LERLGLGDRANKKVEELSKGNQQKVQLIAA 143

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 157 LAQEADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:COG4152   144 LLHDPELLILDEPFSGLDPVNVELLKDVIRELAA-KGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEI 216
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 25-230 5.94e-33

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 121.40  E-value: 5.94e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHP-LGMTVEEVVSY 103
Cdd:PRK13648   28 VSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKHIGIVFQNPDNQfVGSIVKYDVAF 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 104 G----RYPYQKFFSGLNEedlhaiqwALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQL 179
Cdd:PRK13648  108 GlenhAVPYDEMHRRVSE--------ALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQ 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 180 EILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK13648  180 NLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEI 229
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
7-222 1.64e-32

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 118.62  E-value: 1.64e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQ-VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA---QKI 82
Cdd:COG2884     2 IRFENVSKRYPGGReALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPylrRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  83 ALLAQssEHPL--GMTVEEVVSYgryPYQkfFSGLNEEDLHA-IQWALEATQLTKlKEREL-SSLSGGQAQRVWIAMALA 158
Cdd:COG2884    82 GVVFQ--DFRLlpDRTVYENVAL---PLR--VTGKSRKEIRRrVREVLDLVGLSD-KAKALpHELSGGEQQRVAIARALV 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 159 QEADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIV 222
Cdd:COG2884   154 NRPELLLADEPTGNLDPETSWEIMELLEEINR-RGTTVLIATHDLELVDRMPKRVLELEDGRLV 216
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 7-225 1.84e-32

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 118.15  E-value: 1.84e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIsTYSPKmlaQKIALLA 86
Cdd:cd03269     1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPL-DIAAR---NRIGYLP 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSY-GRypyqkfFSGLNEED-LHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:cd03269    77 EERGLYPKMKVIDQLVYlAQ------LKGLKKEEaRRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELL 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 165 ILDEPTTFLDPAHQleiLHLLKEINHIKQ--TTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03269   151 ILDEPFSGLDPVNV---ELLKDVIRELARagKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 26-225 2.04e-32

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 118.36  E-value: 2.04e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP-----KMLAQKIALLAQssehplgMTVEEV 100
Cdd:cd03298    18 DLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPadrpvSMLFQENNLFAH-------LTVEQN 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYGRYPYQKffsgLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLE 180
Cdd:cd03298    91 VGLGLSPGLK----LTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAE 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1560390145 181 ILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03298   167 MLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
cbiO PRK13650
energy-coupling factor transporter ATPase;
1-229 4.86e-32

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 119.07  E-value: 4.86e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLttIEAVDITTGYLNKQ---VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKM 77
Cdd:PRK13650    1 MSNI--IEVKNLTFKYKEDQekyTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  78 LAQKIALLAQSSEHP-LGMTVEEVVSYGR----YPYQKFFSGLNEedlhaiqwALEATQLTKLKERELSSLSGGQAQRVW 152
Cdd:PRK13650   79 IRHKIGMVFQNPDNQfVGATVEDDVAFGLenkgIPHEEMKERVNE--------ALELVGMQDFKEREPARLSGGQKQRVA 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASrFSDYLIGMKAGQIVVQGTPDE 229
Cdd:PRK13650  151 IAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEVA-LSDRVLVMKNGQVESTSTPRE 226
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 26-233 6.38e-32

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 118.51  E-value: 6.38e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-----------MLAQKIALLAQssehplg 94
Cdd:cd03294    44 SLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKelrelrrkkisMVFQSFALLPH------- 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 MTVEEVVSYGRYpyqkfFSGLNEEDLH--AIQwALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:cd03294   117 RTVLENVAFGLE-----VQGVPRAEREerAAE-ALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSA 190

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 173 LDP----AHQLEILHLLKEInhikQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITT 233
Cdd:cd03294   191 LDPlirrEMQDELLRLQAEL----QKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTN 251
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 7-248 7.03e-32

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 117.88  E-value: 7.03e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGK-IIVDGSEISTYSPKMLAQKIALL 85
Cdd:COG1119     4 LELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNdVRLFGERRGGEDVWELRKRIGLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQS--SEHPLGMTVEEVV------SYGRYPYqkffsgLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMAL 157
Cdd:COG1119    84 SPAlqLRFPRDETVLDVVlsgffdSIGLYRE------PTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARAL 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 158 AQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHD-------INHAsrfsdylIGMKAGQIVVQGTPDEV 230
Cdd:COG1119   158 VKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHveeippgITHV-------LLLKDGRVVAAGPKEEV 230

                         250
                  ....*....|....*...
gi 1560390145 231 ITTSWMREIYEIEAQIIE 248
Cdd:COG1119   231 LTSENLSEAFGLPVEVER 248
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 7-202 7.06e-32

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 116.42  E-value: 7.06e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTySPKMLAQKIALLA 86
Cdd:COG4133     3 LEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRD-AREDYRRRLAYLG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEvvsygrypYQKFFSGLNEEDLHAIQW--ALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:COG4133    82 HADGLKPELTVRE--------NLRFWAALYGLRADREAIdeALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLW 153

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEinHIKQ-TTILMSIHD 202
Cdd:COG4133   154 LLDEPFTALDAAGVALLAELIAA--HLARgGAVLLTTHQ 190
cbiO PRK13640
energy-coupling factor transporter ATPase;
3-230 1.00e-31

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 118.36  E-value: 1.00e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   3 NLTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLL---PVKEGKIIVDGSEISTYSPKMLA 79
Cdd:PRK13640    4 NIVEFKHVSFTYPDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLlpdDNPNSKITVDGITLTAKTVWDIR 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  80 QKIALLAQSSEHP-LGMTVEEVVSYG----RYPYQKFfsglneedLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIA 154
Cdd:PRK13640   84 EKVGIVFQNPDNQfVGATVGDDVAFGlenrAVPRPEM--------IKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIA 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 155 MALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK13640  156 GILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEANM-ADQVLVLDDGKLLAQGSPVEI 230
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 5-230 2.41e-31

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 118.64  E-value: 2.41e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   5 TTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-----MLA 79
Cdd:COG3839     2 ASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKdrniaMVF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  80 QKIALLaqssEHplgMTVEEVVSYG-RypyqkfFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMAL 157
Cdd:COG3839    82 QSYALY----PH---MTVYENIAFPlK------LRKVPKAEIDRrVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRAL 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 158 AQEADILILDEPTTFLDPA--HQL--EILHLLKEINhikqTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:COG3839   149 VREPKVFLLDEPLSNLDAKlrVEMraEIKRLHRRLG----TTTIYVTHDQVEAMTLADRIAVMNDGRIQQVGTPEEL 221
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
6-234 7.92e-31

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 115.75  E-value: 7.92e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQV-IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStyspKMLAQK-IA 83
Cdd:PRK15056    6 GIVVNDVTVTWRNGHTaLRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTR----QALQKNlVA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  84 LLAQSSE--HPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEA 161
Cdd:PRK15056   82 YVPQSEEvdWSFPVLVEDVVMMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQG 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 162 DILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIgMKAGQIVVQGTPDEVITTS 234
Cdd:PRK15056  162 QVILLDEPFTGVDVKTEARIISLLRELRD-EGKTMLVSTHNLGSVTEFCDYTV-MVKGTVLASGPTETTFTAE 232
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
 8-233 9.36e-31

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 114.54  E-value: 9.36e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   8 EAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQK-IALLA 86
Cdd:TIGR03410   2 EVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERARAgIAYVP 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSE-HPLgMTVEEVVSYGrypyqkfFSGLNEEDLHAIQWALEA-TQLTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:TIGR03410  82 QGREiFPR-LTVEENLLTG-------LAALPRRSRKIPDEIYELfPVLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLL 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITT 233
Cdd:TIGR03410 154 LLDEPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDELDED 222
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 7-230 1.08e-30

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 114.94  E-value: 1.08e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK-----EGKIIVDGSEIstYSPKM---- 77
Cdd:PRK14267    5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNeearvEGEVRLFGRNI--YSPDVdpie 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  78 LAQKIALLAQSSEHPLGMTVEEVVSYGrYPYQKFFSGLNEEDlHAIQWALEATQL-TKLKER---ELSSLSGGQAQRVWI 153
Cdd:PRK14267   83 VRREVGMVFQYPNPFPHLTIYDNVAIG-VKLNGLVKSKKELD-ERVEWALKKAALwDEVKDRlndYPSNLSGGQRQRLVI 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 154 AMALAQEADILILDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK14267  161 ARALAMKPKILLMDEPTANIDPVGTAKIEELLFELK--KEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKV 235
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 7-232 3.25e-30

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 114.13  E-value: 3.25e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYL-NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:PRK13652    4 IETRDLCYSYSgSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPL-GMTVEEVVSYGryPYQKffsGLNEEDL-HAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADI 163
Cdd:PRK13652   84 FQNPDDQIfSPTVEQDIAFG--PINL---GLDEETVaHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQV 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 164 LILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:PRK13652  159 LVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFL 227
cbiO PRK13642
energy-coupling factor transporter ATPase;
25-234 1.20e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 112.88  E-value: 1.20e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHP-LGMTVEEVVSY 103
Cdd:PRK13642   26 VSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRRKIGMVFQNPDNQfVGATVEDDVAF 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 104 GRYPyqkffSGL-NEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEIL 182
Cdd:PRK13642  106 GMEN-----QGIpREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIM 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 183 HLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVITTS 234
Cdd:PRK13642  181 RVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATS 231
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 6-230 1.26e-29

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 111.66  E-value: 1.26e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-----MLAQ 80
Cdd:cd03296     2 SIEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQernvgFVFQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 KIALLaqssEHplgMTVEEVVSYGrYPYQKFFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQ 159
Cdd:cd03296    82 HYALF----RH---MTVFDNVAFG-LRVKPRSERPPEAEIRAkVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAV 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 160 EADILILDEPTTFLDPAHQLEILHLLKEINH-IKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:cd03296   154 EPKVLLLDEPFGALDAKVRKELRRWLRRLHDeLHVTTVFVT-HDQEEALEVADRVVVMNKGRIEQVGTPDEV 224
cbiO PRK13649
energy-coupling factor transporter ATPase;
25-230 2.05e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 112.15  E-value: 2.05e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP----KMLAQKIALLAQSSEHPL-GMTVEE 99
Cdd:PRK13649   26 VNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKnkdiKQIRKKVGLVFQFPESQLfEETVLK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 VVSYGRypyQKFfsGLNEEDlhAIQWALEATQLT----KLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDP 175
Cdd:PRK13649  106 DVAFGP---QNF--GVSQEE--AEALAREKLALVgiseSLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDP 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 176 AHQLEILHLLKEInHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK13649  179 KGRKELMTLFKKL-HQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDI 232
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 5-212 2.53e-29

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 111.41  E-value: 2.53e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   5 TTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTR---LLPV--KEGKIIVDGSEI--STYSPKM 77
Cdd:PRK14243    9 TVLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRlndLIPGfrVEGKVTFHGKNLyaPDVDPVE 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  78 LAQKIALLAQSSeHPLGMTVEEVVSYGRY--PYQKFFSGLNEEDLHaiQWALEATQLTKLKERELSsLSGGQAQRVWIAM 155
Cdd:PRK14243   89 VRRRIGMVFQKP-NPFPKSIYDNIAYGARinGYKGDMDELVERSLR--QAALWDEVKDKLKQSGLS-LSGGQQQRLCIAR 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 156 ALAQEADILILDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRFSDY 212
Cdd:PRK14243  165 AIAVQPEVILMDEPCSALDPISTLRIEELMHELK--EQYTIIIVTHNMQQAARVSDM 219
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 7-222 4.85e-29

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 109.48  E-value: 4.85e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQ----VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK--MLAQ 80
Cdd:cd03293     1 LEVRNVSKTYGGGGgavtALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPDrgYVFQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 KIALLaqssehPLgMTVEEVVSYGRypyqKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:cd03293    81 QDALL------PW-LTVLDNVALGL----ELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVD 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 161 ADILILDEPTTFLDpAHQLEILH-LLKEINHIKQTTILMSIHDINHASRFSDYLIGMKA--GQIV 222
Cdd:cd03293   150 PDVLLLDEPFSALD-ALTREQLQeELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLSArpGRIV 213
cbiO PRK13641
energy-coupling factor transporter ATPase;
17-240 5.24e-29

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 111.46  E-value: 5.24e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  17 LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDG----SEISTYSPKMLAQKIALLAQSSEHP 92
Cdd:PRK13641   18 MEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGyhitPETGNKNLKKLRKKVSLVFQFPEAQ 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  93 L-GMTVEEVVSYGryPYQKFFSGlNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:PRK13641   98 LfENTVLKDVEFG--PKNFGFSE-DEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAA 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 172 FLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTS-WMREIY 240
Cdd:PRK13641  175 GLDPEGRKEMMQLFKDYQKAGHTVILVT-HNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKeWLKKHY 243
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 7-230 5.57e-29

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 109.63  E-value: 5.57e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP-----KMLAQK 81
Cdd:cd03300     1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPhkrpvNTVFQN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IALLAQssehplgMTVEEVVSYGRYpyqkfFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:cd03300    81 YALFPH-------LTVFENIAFGLR-----LKKLPKAEIKErVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNE 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:cd03300   149 PKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEI 218
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 6-185 7.88e-29

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 114.38  E-value: 7.88e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQ-VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:TIGR02868 334 TLELRDLSAGYPGAPpVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSV 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSeHPLGMTVEEVVSYGRypyqkffSGLNEEDLhaiQWALEATQL------------TKLKERElSSLSGGQAQRVW 152
Cdd:TIGR02868 414 CAQDA-HLFDTTVRENLRLAR-------PDATDEEL---WAALERVGLadwlralpdgldTVLGEGG-ARLSGGERQRLA 481

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAHQLEILHLL 185
Cdd:TIGR02868 482 LARALLADAPILLLDEPTEHLDAETADELLEDL 514
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 7-231 1.04e-28

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 109.24  E-value: 1.04e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQ--VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:cd03251     1 VEFKNVTFRYPGDGppVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLRRQIGL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSeHPLGMTVEEVVSYGRypyqkffSGLNEEDLHAIQWALEATQL---------TKLKERElSSLSGGQAQRVWIAM 155
Cdd:cd03251    81 VSQDV-FLFNDTVAENIAYGR-------PGATREEVEEAARAANAHEFimelpegydTVIGERG-VKLSGGQRQRIAIAR 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 156 ALAQEADILILDEPTTFLDP----AHQLEILHLLKEinhikQTTILMsihdinhASRFS-----DYLIGMKAGQIVVQGT 226
Cdd:cd03251   152 ALLKDPPILILDEATSALDTeserLVQAALERLMKN-----RTTFVI-------AHRLStienaDRIVVLEDGKIVERGT 219


                  ....*
gi 1560390145 227 PDEVI 231
Cdd:cd03251   220 HEELL 224
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 7-231 2.03e-28

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 108.44  E-value: 2.03e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNK----QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKML---A 79
Cdd:cd03258     2 IELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELrkaR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  80 QKIALLAQ-----SSEhplgmTVEEVVSYgryPYQKffsgLNEEDLHAIQWALEATQLTKLKERE---LSSLSGGQAQRV 151
Cdd:cd03258    82 RRIGMIFQhfnllSSR-----TVFENVAL---PLEI----AGVPKAEIEERVLELLELVGLEDKAdayPAQLSGGQKQRV 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 152 WIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:cd03258   150 GIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVF 229
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 19-222 3.01e-28

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 108.64  E-value: 3.01e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK--MLAQKIALLaqssehPLgMT 96
Cdd:COG1116    24 VTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPDrgVVFQEPALL------PW-LT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  97 VEEVVSYGrypyQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPttF--LD 174
Cdd:COG1116    97 VLDNVALG----LELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLLMDEP--FgaLD 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 175 P---AH-QLEILHLLKEinhiKQTTILMSIHDINHASRFSDYLIGMKA--GQIV 222
Cdd:COG1116   171 AltrERlQDELLRLWQE----TGKTVLFVTHDVDEAVFLADRVVVLSArpGRIV 220
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
2-231 3.47e-28

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 110.31  E-value: 3.47e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   2 KNLTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSpKMLAQK 81
Cdd:PRK13536   37 MSTVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARA-RLARAR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IALLAQSSEHPLGMTVEE-VVSYGRYpyqkffSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQ 159
Cdd:PRK13536  116 IGVVPQFDNLDLEFTVREnLLVFGRY------FGMSTREIEAvIPSLLEFARLESKADARVSDLSGGMKRRLTLARALIN 189

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 160 EADILILDEPTTFLDPAHQLEILHLLKEInHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:PRK13536  190 DPQLLILDEPTTGLDPHARHLIWERLRSL-LARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALI 260
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 7-231 3.60e-28

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 107.70  E-value: 3.60e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGY-LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:cd03253     1 IEFENVTFAYdPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRRAIGVV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSehPL-GMTVEEVVSYGRypyqkfFSGLNEE--------DLHAIQWALEATQLTKLKERELsSLSGGQAQRVWIAMA 156
Cdd:cd03253    81 PQDT--VLfNDTIGYNIRYGR------PDATDEEvieaakaaQIHDKIMRFPDGYDTIVGERGL-KLSGGEKQRVAIARA 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 157 LAQEADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMS--IHDINHAsrfsDYLIGMKAGQIVVQGTPDEVI 231
Cdd:cd03253   152 ILKNPPILLLDEATSALDTHTEREIQAALRDVSK-GRTTIVIAhrLSTIVNA----DKIIVLKDGRIVERGTHEELL 223
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
18-249 3.84e-28

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 108.64  E-value: 3.84e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseISTYSPKML---AQKIALLAQSSEHPLG 94
Cdd:PRK13633   22 EKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDG--LDTSDEENLwdiRNKAGMVFQNPDNQIV 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 MT-VEEVVSYGryPYQKffsGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:PRK13633  100 ATiVEEDVAFG--PENL---GIPPEEIRErVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAM 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 173 LDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVIT-TSWMREIYEIEAQIIEL 249
Cdd:PRK13633  175 LDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIFKeVEMMKKIGLDVPQVTEL 251
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 20-231 4.18e-28

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 107.63  E-value: 4.18e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  20 QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSsehP--LGMTV 97
Cdd:cd03249    17 PILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQIGLVSQE---PvlFDGTI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  98 EEVVSYGRypyqkfFSGLNEEDLHAIQWALEATQLTKLKER---EL----SSLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:cd03249    94 AENIRYGK------PDATDEEVEEAAKKANIHDFIMSLPDGydtLVgergSQLSGGQKQRIAIARALLRNPKILLLDEAT 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 171 TFLDPAHQLEILHLLKEInhIKQTTILMSIHDInHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:cd03249   168 SALDAESEKLVQEALDRA--MKGRTTIVIAHRL-STIRNADLIAVLQNGQVVEQGTHDELM 225
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
 25-229 7.03e-28

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 108.63  E-value: 7.03e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIsTYSPKMLAQKIALLAQSSEHPLGMTVEE-VVSY 103
Cdd:TIGR01188  12 VNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDV-VREPRKVRRSIGIVPQYASVDEDLTGREnLEMM 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 104 GRypyqkfFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEIL 182
Cdd:TIGR01188  91 GR------LYGLPKDEAEErAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTRRAIW 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1560390145 183 HLLKEINHIKqTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:TIGR01188 165 DYIRALKEEG-VTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEE 210
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 7-240 9.87e-28

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 106.47  E-value: 9.87e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQK-IALL 85
Cdd:cd03218     1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLgIGYL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPLGMTVEE---VVSYGRYPyqkffsgLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEAD 162
Cdd:cd03218    81 PQEASIFRKLTVEEnilAVLEIRGL-------SKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPK 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 163 ILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSD--YLIGmkAGQIVVQGTPDEVITTSWMREIY 240
Cdd:cd03218   154 FLLLDEPFAGVDPIAVQDIQKIIKILKD-RGIGVLITDHNVRETLSITDraYIIY--EGKVLAEGTPEEIAANELVRKVY 230
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 7-225 9.98e-28

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 106.30  E-value: 9.98e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNK----QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTySPKMLAQKI 82
Cdd:cd03266     2 ITADALTKRFRDVkktvQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVK-EPAEARRRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  83 ALLAQSSEHPLGMTVEEVVSY-GRypyqkfFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:cd03266    81 GFVSDSTGLYDRLTARENLEYfAG------LYGLKGDELTArLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHD 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 161 ADILILDEPTTFLD---PAHQLEILHLLKEinhiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03266   155 PPVLLLDEPTTGLDvmaTRALREFIRQLRA----LGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 7-225 2.99e-27

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 104.61  E-value: 2.99e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKmlAQKIALLA 86
Cdd:cd03268     1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEA--LRRIGALI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYGRYPYqkffsGLNEEDlhaIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:cd03268    79 EAPGFYPNLTARENLRLLARLL-----GIRKKR---IDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLIL 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 167 DEPTTFLDPAHQLEILHLLkeINHIKQ-TTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03268   151 DEPTNGLDPDGIKELRELI--LSLRDQgITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
3-230 3.27e-27

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 106.00  E-value: 3.27e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   3 NLTTIEAVDITTGylNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQ-- 80
Cdd:PRK11831    6 NLVDMRGVSFTRG--NRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTvr 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 -KIALLAQSSEHPLGMTVEEVVSYgryPYQKFfSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALA 158
Cdd:PRK11831   84 kRMSMLFQSGALFTDMNVFDNVAY---PLREH-TQLPAPLLHStVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 159 QEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK11831  160 LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
6-230 4.68e-27

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 107.48  E-value: 4.68e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-----MLAQ 80
Cdd:PRK10851    2 SIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARdrkvgFVFQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 KIALLaqssEHplgMTVEEVVSYG--RYPYQKffsglnEEDLHAIQWA----LEATQLTKLKERELSSLSGGQAQRVWIA 154
Cdd:PRK10851   82 HYALF----RH---MTVFDNIAFGltVLPRRE------RPNAAAIKAKvtqlLEMVQLAHLADRYPAQLSGGQKQRVALA 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 155 MALAQEADILILDEPTTFLDPAHQLEILHLLKEI-NHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK10851  149 RALAVEPQILLLDEPFGALDAQVRKELRRWLRQLhEELKFTSVFVT-HDQEEAMEVADRVVVMSQGNIEQAGTPDQV 224
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
26-232 6.08e-27

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 104.28  E-value: 6.08e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP-----KMLAQKIALLAqsseHplgMTVEEV 100
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPsrrpvSMLFQENNLFS----H---LTVAQN 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYGRYPYQKffsgLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLE 180
Cdd:PRK10771   92 IGLGLNPGLK----LNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQE 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 181 ILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:PRK10771  168 MLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDELLS 219
cbiO PRK13644
energy-coupling factor transporter ATPase;
22-254 1.08e-26

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 104.68  E-value: 1.08e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKI-ALLAQSSEHP-LGMTVEE 99
Cdd:PRK13644   18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIRKLvGIVFQNPETQfVGRTVEE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 VVSYGryPYQKFFSGLneEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQL 179
Cdd:PRK13644   98 DLAFG--PENLCLPPI--EIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDPDSGI 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 180 EILHLLKEInHIKQTTILMSIHDINHAsRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQIIELPETNK 254
Cdd:PRK13644  174 AVLERIKKL-HEKGKTIVYITHNLEEL-HDADRIIVMDRGKIVLEGEPENVLSDVSLQTLGLTPPSLIELAENLK 246
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 21-216 1.56e-26

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 107.76  E-value: 1.56e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQsseHPLGM--TVE 98
Cdd:TIGR02857 337 ALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQIAWVPQ---HPFLFagTIA 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  99 EVVSYGRypyqkffsglNEEDLHAIQWALEATQL------------TKLKERElSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:TIGR02857 414 ENIRLAR----------PDASDAEIREALERAGLdefvaalpqgldTPIGEGG-AGLSGGQAQRLALARAFLRDAPLLLL 482

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 167 DEPTTFLDPAHQLEIlhlLKEINHIKQT-TILMSIHDINHASRfSDYLIGM 216
Cdd:TIGR02857 483 DEPTAHLDAETEAEV---LEALRALAQGrTVLLVTHRLALAAL-ADRIVVL 529
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 19-223 1.70e-26

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 104.01  E-value: 1.70e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSsehPL----- 93
Cdd:COG1101    19 KRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAKYIGRVFQD---PMmgtap 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 GMTVEE--VVSYGRYPYQKFFSGLNEEDLHAIQWALEATQL---TKLKEReLSSLSGGQAQRVWIAMALAQEADILILDE 168
Cdd:COG1101    96 SMTIEEnlALAYRRGKRRGLRRGLTKKRRELFRELLATLGLgleNRLDTK-VGLLSGGQRQALSLLMATLTKPKLLLLDE 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 169 PTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVV 223
Cdd:COG1101   175 HTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRIIL 229
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 11-211 3.59e-26

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 102.93  E-value: 3.59e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  11 DITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTR---LLP--VKEGKIIVDGSEIstYSPKM----LAQK 81
Cdd:PRK14239   10 DLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRmndLNPevTITGSIVYNGHNI--YSPRTdtvdLRKE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IALLAQSSeHPLGMTVEEVVSYGRYpyqkfFSGLNEEDL--HAIQWALEATQL-TKLKERELSS---LSGGQAQRVWIAM 155
Cdd:PRK14239   88 IGMVFQQP-NPFPMSIYENVVYGLR-----LKGIKDKQVldEAVEKSLKGASIwDEVKDRLHDSalgLSGGQQQRVCIAR 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 156 ALAQEADILILDEPTTFLDP--AHQLE-ILHLLKeinhiKQTTILMSIHDINHASRFSD 211
Cdd:PRK14239  162 VLATSPKIILLDEPTSALDPisAGKIEeTLLGLK-----DDYTMLLVTRSMQQASRISD 215
potA TIGR01187
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...
 37-241 4.29e-26

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 162242 [Multi-domain]  Cd Length: 325  Bit Score: 104.11  E-value: 4.29e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  37 LIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-----MLAQKIALLAQssehplgMTVEEVVSYGrypyQKF 111
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVTNVPPHlrhinMVFQSYALFPH-------MTVEENVAFG----LKM 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 112 FSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHI 191
Cdd:TIGR01187  70 RKVPRAEIKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQ 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1560390145 192 KQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPdevittswmREIYE 241
Cdd:TIGR01187 150 LGITFVFVTHDQEEAMTMSDRIAIMRKGKIAQIGTP---------EEIYE 190
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 7-225 6.90e-26

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 100.08  E-value: 6.90e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYL--NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSpKMLAQKIAL 84
Cdd:cd03247     1 LSINNVSFSYPeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLE-KALSSLISV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSsehplgmtveevvsygryPYqkFFSGlneedlhaiqwaleaTQLTKLKERelssLSGGQAQRVWIAMALAQEADIL 164
Cdd:cd03247    80 LNQR------------------PY--LFDT---------------TLRNNLGRR----FSGGERQRLALARILLQDAPIV 120

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEinHIKQTTILMSIHDINHASRFsDYLIGMKAGQIVVQG 225
Cdd:cd03247   121 LLDEPTVGLDPITERQLLSLIFE--VLKDKTLIWITHHLTGIEHM-DKILFLENGKIIMQG 178
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 19-225 8.74e-26

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 101.19  E-value: 8.74e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP---VKEGKIIVDGSEIStysPKMLAQKIALLAQSSEHPLGM 95
Cdd:cd03234    20 ARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEgggTTSGQILFNGQPRK---PDQFQKCVAYVRQDDILLPGL 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 TVEEVVSY-----GRYPYQKFFSGLNEEDLhaiqwALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:cd03234    97 TVRETLTYtailrLPRKSSDAIRKKRVEDV-----LLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPT 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 171 TFLDPAHQLEILHLLKEINHiKQTTILMSIH----DInhaSRFSDYLIGMKAGQIVVQG 225
Cdd:cd03234   172 SGLDSFTALNLVSTLSQLAR-RNRIVILTIHqprsDL---FRLFDRILLLSSGEIVYSG 226
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 2-233 1.63e-25

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 101.27  E-value: 1.63e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   2 KNLTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVkEGKIIVDGsEISTYSPKMLAQK 81
Cdd:PRK14258    3 KLIPAIKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNEL-ESEVRVEG-RVEFFNQNIYERR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IAL----LAQSSEHP----LGMTVEEVVSYGrypyQKFFSGLNEEDLHAI-QWALEATQL-----TKLKERELSsLSGGQ 147
Cdd:PRK14258   81 VNLnrlrRQVSMVHPkpnlFPMSVYDNVAYG----VKIVGWRPKLEIDDIvESALKDADLwdeikHKIHKSALD-LSGGQ 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 148 AQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKA-----GQIV 222
Cdd:PRK14258  156 QQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLV 235

                         250
                  ....*....|.
gi 1560390145 223 VQGTPDEVITT 233
Cdd:PRK14258  236 EFGLTKKIFNS 246
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 7-222 1.89e-25

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 100.02  E-value: 1.89e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-----MLAQK 81
Cdd:cd03301     1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKdrdiaMVFQN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IALlaqsseHPlGMTVEEVVSYGrypyQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEA 161
Cdd:cd03301    81 YAL------YP-HMTVYDNIAFG----LKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREP 149

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 162 DILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIV 222
Cdd:cd03301   150 KVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQIQ 210
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 31-225 2.00e-25

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 100.06  E-value: 2.00e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  31 EGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDG-----SEISTYSPKMlAQKIALLAQSSEHPLGMTVEEVVSYGr 105
Cdd:cd03297    22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGtvlfdSRKKINLPPQ-QRKIGLVFQQYALFPHLNVRENLAFG- 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 106 ypyQKFFSglNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLL 185
Cdd:cd03297   100 ---LKRKR--NREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPEL 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1560390145 186 KEI-NHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03297   175 KQIkKNLNIPVIFVT-HDLSEAEYLADRIVVMEDGRLQYIG 214
cbiO PRK13646
energy-coupling factor transporter ATPase;
19-262 2.22e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 101.39  E-value: 2.22e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP----KMLAQKIALLAQSSEHPLG 94
Cdd:PRK13646   20 HQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKdkyiRPVRKRIGMVFQFPESQLF 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 M-TVEEVVSYGRypyQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFL 173
Cdd:PRK13646  100 EdTVEREIIFGP---KNFKMNLDEVKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAGL 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 174 DPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVittswMREIYEIEAQIIELPETn 253
Cdd:PRK13646  177 DPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKEL-----FKDKKKLADWHIGLPEI- 250


                  ....*....
gi 1560390145 254 kpVVLSYDL 262
Cdd:PRK13646  251 --VQLQYDF 257
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 7-222 2.25e-25

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 98.27  E-value: 2.25e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-MLAQKIAll 85
Cdd:cd03216     1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRdARRAGIA-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 aqssehplgmTVeevvsygrypYQkffsglneedlhaiqwaleatqltklkerelssLSGGQAQRVWIAMALAQEADILI 165
Cdd:cd03216    79 ----------MV----------YQ---------------------------------LSVGERQMVEIARALARNARLLI 105

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 166 LDEPTTFLDPAhqlEILHLLKEINHIKQ--TTILMSIHDINHASRFSDYLIGMKAGQIV 222
Cdd:cd03216   106 LDEPTAALTPA---EVERLFKVIRRLRAqgVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
type_I_sec_LssB TIGR03375
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ...
 7-232 2.49e-25

type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274550 [Multi-domain]  Cd Length: 694  Bit Score: 104.95  E-value: 2.49e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQ--VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:TIGR03375 464 IEFRNVSFAYPGQEtpALDNVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLLDGVDIRQIDPADLRRNIGY 543

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHPLGmTVEEVVSYGRyPYqkffsgLNEEDlhaIQWALEATQLTKLKERELS-----------SLSGGQAQRVWI 153
Cdd:TIGR03375 544 VPQDPRLFYG-TLRDNIALGA-PY------ADDEE---ILRAAELAGVTEFVRRHPDgldmqigergrSLSGGQRQAVAL 612

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 154 AMALAQEADILILDEPTTFLDPAHQLEILHLLKEInhIKQTTILMSIHdinhasRFS-----DYLIGMKAGQIVVQGTPD 228
Cdd:TIGR03375 613 ARALLRDPPILLLDEPTSAMDNRSEERFKDRLKRW--LAGKTLVLVTH------RTSlldlvDRIIVMDNGRIVADGPKD 684


                  ....
gi 1560390145 229 EVIT 232
Cdd:TIGR03375 685 QVLE 688
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 26-231 2.50e-25

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 100.10  E-value: 2.50e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMlaQKIALLAQssEHPL--GMTVEEVVSY 103
Cdd:cd03299    19 SLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEK--RDISYVPQ--NYALfpHMTVYKNIAY 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 104 G----RYPYQKFfsglnEEDLHAIQwalEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQL 179
Cdd:cd03299    95 GlkkrKVDKKEI-----ERKVLEIA---EMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKE 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 180 EILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:cd03299   167 KLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVF 218
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 8-231 4.98e-25

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 103.64  E-value: 4.98e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   8 EAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQ 87
Cdd:TIGR02203 334 RNVTFRYPGRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLRRQVALVSQ 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 SSeHPLGMTVEEVVSYGRypyqkffsgLNEEDLHAIQWALEATQLTKLKER-----------ELSSLSGGQAQRVWIAMA 156
Cdd:TIGR02203 414 DV-VLFNDTIANNIAYGR---------TEQADRAEIERALAAAYAQDFVDKlplgldtpigeNGVLLSGGQRQRLAIARA 483

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 157 LAQEADILILDEPTTFLDPAHQLEILHLLKEInhIKQTTILMSIH---DINHAsrfsDYLIGMKAGQIVVQGTPDEVI 231
Cdd:TIGR02203 484 LLKDAPILILDEATSALDNESERLVQAALERL--MQGRTTLVIAHrlsTIEKA----DRIVVMDDGRIVERGTHNELL 555
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 18-231 5.52e-25

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 99.22  E-value: 5.52e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSeHPLGMTV 97
Cdd:cd03254    15 KKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSMIGVVLQDT-FLFSGTI 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  98 EEVVSYGRypyqkffSGLNEEDLHAIQWALEATQL---------TKLKERElSSLSGGQAQRVWIAMALAQEADILILDE 168
Cdd:cd03254    94 MENIRLGR-------PNATDEEVIEAAKEAGAHDFimklpngydTVLGENG-GNLSQGERQLLAIARAMLRDPKILILDE 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 169 PTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINhASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:cd03254   166 ATSNIDTETEKLIQEALEKLM--KGRTSIIIAHRLS-TIKNADKILVLDDGKIIEEGTHDELL 225
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 11-221 7.50e-25

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 98.70  E-value: 7.50e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  11 DITTGYLNK---QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQ 87
Cdd:cd03248    16 NVTFAYPTRpdtLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHSKVSLVGQ 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 ssEHPL-GMTVEEVVSYG--RYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERElSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:cd03248    96 --EPVLfARSLQDNIAYGlqSCSFECVKEAAQKAHAHSFISELASGYDTEVGEKG-SQLSGGQKQRVAIARALIRNPQVL 172

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRfSDYLIGMKAGQI 221
Cdd:cd03248   173 ILDEATSALDAESEQQVQQALYDWP--ERRTVLVIAHRLSTVER-ADQILVLDGGRI 226
cbiO PRK13643
energy-coupling factor transporter ATPase;
25-230 9.10e-25

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 100.19  E-value: 9.10e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP----KMLAQKIALLAQSSEHPL-GMTVEE 99
Cdd:PRK13643   25 IDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKqkeiKPVRKKVGVVFQFPESQLfEETVLK 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 VVSYGRypyQKFfsGLNEEDLHAIQW-ALEATQLTK-LKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAH 177
Cdd:PRK13643  105 DVAFGP---QNF--GIPKEKAEKIAAeKLEMVGLADeFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKA 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 178 QLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK13643  180 RIEMMQLFESIHQSGQTVVLVT-HLMDDVADYADYVYLLEKGHIISCGTPSDV 231
thiQ TIGR01277
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...
 16-225 1.14e-24

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]


Pssm-ID: 130344 [Multi-domain]  Cd Length: 213  Bit Score: 98.01  E-value: 1.14e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  16 YLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP-----KMLAQKIALLAQsse 90
Cdd:TIGR01277   8 YEYEHLPMEFDLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPyqrpvSMLFQENNLFAH--- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  91 hplgMTVEEVVSYGRYPYQKffsgLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:TIGR01277  85 ----LTVRQNIGLGLHPGLK----LNAEQQEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPF 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 171 TFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:TIGR01277 157 SALDPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIKVVS 211
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
26-232 1.14e-24

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 100.54  E-value: 1.14e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA---QKI-------ALLAQSsehplgm 95
Cdd:COG1135    25 SLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRaarRKIgmifqhfNLLSSR------- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 TVEEVVSYgryPYQkfFSGLNEEDLHAIqwALEATQLTKLKERE---LSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:COG1135    98 TVAENVAL---PLE--IAGVPKAEIRKR--VAELLELVGLSDKAdayPSQLSGGQKQRVGIARALANNPKVLLCDEATSA 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 173 LDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:COG1135   171 LDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFA 230
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 7-202 1.17e-24

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 97.86  E-value: 1.17e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQV-IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK---MLAQKI 82
Cdd:cd03292     1 IEFINVTKTYPNGTAaLDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRaipYLRRKI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  83 ALLAQSSEHPLGMTVEEVVSYGRYPYQKFFSGLNEEdlhaIQWALEATQLtKLKERELSS-LSGGQAQRVWIAMALAQEA 161
Cdd:cd03292    81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKR----VPAALELVGL-SHKHRALPAeLSGGEQQRVAIARAIVNSP 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1560390145 162 DILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHD 202
Cdd:cd03292   156 TILIADEPTGNLDPDTTWEIMNLLKKINK-AGTTVVVATHA 195
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 18-232 1.75e-24

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 102.49  E-value: 1.75e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQsseHPLGM-- 95
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHRQVALVGQ---EPVLFsg 569

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 TVEEVVSYG--RYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERElSSLSGGQAQRVWIAMALAQEADILILDEPTTFL 173
Cdd:TIGR00958 570 SVRENIAYGltDTPDEEIMAAAKAANAHDFIMEFPNGYDTEVGEKG-SQLSGGQKQRIAIARALVRKPRVLILDEATSAL 648

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 174 DpahqLEILHLLKEINHIKQTTILMSIHDInHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:TIGR00958 649 D----AECEQLLQESRSRASRTVLLIAHRL-STVERADQILVLKKGSVVEMGTHKQLME 702
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 26-251 2.06e-24

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 99.88  E-value: 2.06e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA---QKIALLAQ-----SSEhplgmTV 97
Cdd:PRK11153   25 SLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRkarRQIGMIFQhfnllSSR-----TV 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  98 EEVVSYgryPYQkfFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPA 176
Cdd:PRK11153  100 FDNVAL---PLE--LAGTPKAEIKArVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPKVLLCDEATSALDPA 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 177 HQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT---TSWMRE-IYEIEAQiiELPE 251
Cdd:PRK11153  175 TTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFShpkHPLTREfIQSTLHL--DLPE 251
L_ocin_972_ABC TIGR03608
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...
 10-202 2.68e-24

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]


Pssm-ID: 188353 [Multi-domain]  Cd Length: 206  Bit Score: 96.92  E-value: 2.68e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  10 VDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK----MLAQKIALL 85
Cdd:TIGR03608   2 KNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKkaskFRREKLGYL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSsehpLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:TIGR03608  82 FQN----FALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLIL 157

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHD 202
Cdd:TIGR03608 158 ADEPTGSLDPKNRDEVLDLLLELND-EGKTIIIVTHD 193
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
16-230 3.36e-24

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 98.16  E-value: 3.36e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  16 YLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA--QKIALLAQSSEHPL 93
Cdd:PRK13638   11 YQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGLLAlrQQVATVFQDPEQQI 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 GMTveEVVSYGRYPYQKFfsGLNEEDL-HAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:PRK13638   91 FYT--DIDSDIAFSLRNL--GVPEAEItRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAG 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 173 LDPAHQLEILHLLKEI----NHikqttILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK13638  167 LDPAGRTQMIAIIRRIvaqgNH-----VIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEV 223
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 7-232 4.88e-24

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 101.05  E-value: 4.88e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQ--VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:PRK11160  339 LTLNNVSFTYPDQPqpVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQAISV 418

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSsehplgmtveevvsygryPYqkFFSG------------LNEEDLHAIqwaLEATQLTKLKERE--LSS-------- 142
Cdd:PRK11160  419 VSQR------------------VH--LFSAtlrdnlllaapnASDEALIEV---LQQVGLEKLLEDDkgLNAwlgeggrq 475

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 143 LSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEinHIKQTTILMSIHDINHASRFsDYLIGMKAGQIV 222
Cdd:PRK11160  476 LSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAE--HAQNKTVLMITHRLTGLEQF-DRICVMDNGQII 552

                         250
                  ....*....|
gi 1560390145 223 VQGTPDEVIT 232
Cdd:PRK11160  553 EQGTHQELLA 562
cbiO PRK13645
energy-coupling factor transporter ATPase;
20-243 7.50e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 97.39  E-value: 7.50e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  20 QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKM-----LAQKIALLAQSSEHPLG 94
Cdd:PRK13645   25 KALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPANLKKIkevkrLRKEIGLVFQFPEYQLF 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 M-TVEEVVSYGryPYQkffsgLNEEDLHAIQWALEATQLTKLKE----RELSSLSGGQAQRVWIAMALAQEADILILDEP 169
Cdd:PRK13645  105 QeTIEKDIAFG--PVN-----LGENKQEAYKKVPELLKLVQLPEdyvkRSPFELSGGQKRRVALAGIIAMDGNTLVLDEP 177

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 170 TTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIE 243
Cdd:PRK13645  178 TGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSNQELLTKIEID 251
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 6-231 8.62e-24

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 96.40  E-value: 8.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:cd03252     2 TFEHVRFRYKPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRRQVGVV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHpLGMTVEEVVSYGR--YPYQKFFSGLNEEDLHAIQWALEATQLTKLKERElSSLSGGQAQRVWIAMALAQEADI 163
Cdd:cd03252    82 LQENVL-FNRSIRDNIALADpgMSMERVIEAAKLAGAHDFISELPEGYDTIVGEQG-AGLSGGQRQRIAIARALIHNPRI 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 164 LILDEPTTFLDPAHQLEILHLLKEInhIKQTTILMSIHDINhASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:cd03252   160 LIFDEATSALDYESEHAIMRNMHDI--CAGRTVIIIAHRLS-TVKNADRIIVMEKGRIVEQGSHDELL 224
FtsE TIGR02673
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...
 26-220 1.72e-23

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]


Pssm-ID: 131721 [Multi-domain]  Cd Length: 214  Bit Score: 94.62  E-value: 1.72e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA---QKIALLAQSSEHPLGMTVEEVVS 102
Cdd:TIGR02673  22 SLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLPllrRRIGVVFQDFRLLPDRTVYENVA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 103 YgryPYQkfFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEI 181
Cdd:TIGR02673 102 L---PLE--VRGKKEREIQRrVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLADEPTGNLDPDLSERI 176

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1560390145 182 LHLLKEInHIKQTTILMSIHDINHASRFSDYLIGMKAGQ 220
Cdd:TIGR02673 177 LDLLKRL-NKRGTTVIVATHDLSLVDRVAHRVIILDDGR 214
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-241 2.07e-23

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 97.71  E-value: 2.07e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK---- 76
Cdd:PRK09452    9 SSLSPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAEnrhv 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  77 -MLAQKIALLAqsseHplgMTVEEVVSYG----RYPYQKFFSGLNEedlhaiqwALEATQLTKLKERELSSLSGGQAQRV 151
Cdd:PRK09452   89 nTVFQSYALFP----H---MTVFENVAFGlrmqKTPAAEITPRVME--------ALRMVQLEEFAQRKPHQLSGGQQQRV 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 152 WIAMALAQEADILILDEPTTFLD----PAHQLEILHLLKEINhikqTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTP 227
Cdd:PRK09452  154 AIARAVVNKPKVLLLDESLSALDyklrKQMQNELKALQRKLG----ITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTP 229

                         250
                  ....*....|....
gi 1560390145 228 devittswmREIYE 241
Cdd:PRK09452  230 ---------REIYE 234
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
1-229 2.16e-23

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 97.48  E-value: 2.16e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK---- 76
Cdd:PRK11432    1 MTQKNFVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQqrdi 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  77 -MLAQKIALLAQssehplgMTVEEVVSYGrypyQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAM 155
Cdd:PRK11432   81 cMVFQSYALFPH-------MSLGENVGYG----LKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALAR 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 156 ALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:PRK11432  150 ALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQE 223
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 7-231 3.41e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 95.92  E-value: 3.41e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNK-----QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIV---------DGSEIST 72
Cdd:PRK13651    3 IKVKNIVKIFNKKlptelKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWifkdeknkkKTKEKEK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  73 YSPKMLAQK---------------IALLAQSSEHPL-GMTVEEVVSYGRYPYqkffsGLNEEDlhAIQWALEATQLTKLK 136
Cdd:PRK13651   83 VLEKLVIQKtrfkkikkikeirrrVGVVFQFAEYQLfEQTIEKDIIFGPVSM-----GVSKEE--AKKRAAKYIELVGLD 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 137 ERELS----SLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEInHIKQTTILMSIHDINHASRFSDY 212
Cdd:PRK13651  156 ESYLQrspfELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNL-NKQGKTIILVTHDLDNVLEWTKR 234

                         250
                  ....*....|....*....
gi 1560390145 213 LIGMKAGQIVVQGTPDEVI 231
Cdd:PRK13651  235 TIFFKDGKIIKDGDTYDIL 253
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 4-225 4.04e-23

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 94.82  E-value: 4.04e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   4 LTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPkmLAQKIA 83
Cdd:PRK11264    1 MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTARS--LSQQKG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  84 LLAQSSEHpLGMTVEevvSYGRYPYQKFFSGLNEEDL--------HAIQWALEATQLTKLKERELS---SLSGGQAQRVW 152
Cdd:PRK11264   79 LIRQLRQH-VGFVFQ---NFNLFPHRTVLENIIEGPVivkgepkeEATARARELLAKVGLAGKETSyprRLSGGQQQRVA 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:PRK11264  155 IARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVT-HEMSFARDVADRAIFMDQGRIVEQG 226
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
5-230 4.78e-23

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 94.65  E-value: 4.78e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   5 TTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-------- 76
Cdd:PRK10619    4 NKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKdgqlkvad 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  77 -----MLAQKIALLAQSSEHPLGMTVEEVVSYGryPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRV 151
Cdd:PRK10619   84 knqlrLLRTRLTMVFQHFNLWSHMTVLENVMEA--PIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQRV 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 152 WIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK10619  162 SIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVT-HEMGFARHVSSHVIFLHQGKIEEEGAPEQL 239
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
5-226 5.24e-23

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 94.69  E-value: 5.24e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   5 TTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP----------------VKEGKIIVDGS 68
Cdd:PRK09984    3 TIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITgdksagshiellgrtvQREGRLARDIR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  69 EiSTYSPKMLAQKIALLAQssehplgMTVEEVV---SYGRYPYQK----FFSGLNEEdlHAIQwALEATQLTKLKERELS 141
Cdd:PRK09984   83 K-SRANTGYIFQQFNLVNR-------LSVLENVligALGSTPFWRtcfsWFTREQKQ--RALQ-ALTRVGMVHFAHQRVS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 142 SLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQI 221
Cdd:PRK09984  152 TLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHV 231


                  ....*
gi 1560390145 222 VVQGT 226
Cdd:PRK09984  232 FYDGS 236
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
22-231 5.51e-23

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 97.03  E-value: 5.51e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQ----KIALLAQSSEHPLGMTV 97
Cdd:PRK10070   44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREvrrkKIAMVFQSFALMPHMTV 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  98 EEVVSYGrypyQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAH 177
Cdd:PRK10070  124 LDNTAFG----MELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLI 199

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 178 QLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:PRK10070  200 RTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEIL 253
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 16-225 5.77e-23

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 93.94  E-value: 5.77e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  16 YLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEH---- 91
Cdd:cd03267    31 YREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKFLRRIGVVFGQKTQLwwdl 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  92 PLGMTVEEVVSYGRYPYQKFFSGLNEedlhaiqwALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:cd03267   111 PVIDSFYLLAAIYDLPPARFKKRLDE--------LSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTI 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 172 FLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03267   183 GLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 11-174 5.83e-23

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 97.44  E-value: 5.83e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  11 DITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEistyspkmlaqKIALLAQSSE 90
Cdd:COG0488     3 NLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGL-----------RIGYLPQEPP 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  91 HPLGMTVEEVVSYGRYPYQKFFSGLNE---------EDLHAIQ-----------WALEA---TQLTKLK------ERELS 141
Cdd:COG0488    72 LDDDLTVLDTVLDGDAELRALEAELEEleaklaepdEDLERLAelqeefealggWEAEAraeEILSGLGfpeedlDRPVS 151

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1560390145 142 SLSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:COG0488   152 ELSGGWRRRVALARALLSEPDLLLLDEPTNHLD 184
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 18-233 6.49e-23

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 94.34  E-value: 6.49e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVD------GSEISTYSPKMLAQKIALLAQSSEH 91
Cdd:PRK14246   22 DKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDgkvlyfGKDIFQIDAIKLRKEVGMVFQQPNP 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  92 PLGMTVEEVVSygrYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSS----LSGGQAQRVWIAMALAQEADILILD 167
Cdd:PRK14246  102 FPHLSIYDNIA---YPLKSHGIKEKREIKKIVEECLRKVGLWKEVYDRLNSpasqLSGGQQQRLTIARALALKPKVLLMD 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 168 EPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITT 233
Cdd:PRK14246  179 EPTSMIDIVNSQAIEKLITELK--NEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTS 242
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
7-231 7.61e-23

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 97.40  E-value: 7.61e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQV--IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:PRK11176  342 IEFRNVTFTYPGKEVpaLRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASLRNQVAL 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSeHPLGMTVEEVVSYGRypyQKFFSglNEEDLHAIQWALEATQLTKLKE-------RELSSLSGGQAQRVWIAMAL 157
Cdd:PRK11176  422 VSQNV-HLFNDTIANNIAYAR---TEQYS--REQIEEAARMAYAMDFINKMDNgldtvigENGVLLSGGQRQRIAIARAL 495

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 158 AQEADILILDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:PRK11176  496 LRDSPILILDEATSALDTESERAIQAALDELQ--KNRTSLVIAHRLSTIEK-ADEILVVEDGEIVERGTHAELL 566
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 31-230 7.74e-23

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 93.90  E-value: 7.74e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  31 EGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA--------QKIALLAQssehplgMTVEE--V 100
Cdd:PRK11300   30 EQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIArmgvvrtfQHVRLFRE-------MTVIEnlL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYGRYPYQKFFSGL---------NEEDL-HAIQWaLEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:PRK11300  103 VAQHQQLKTGLFSGLlktpafrraESEALdRAATW-LERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPA 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 171 TFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK11300  182 AGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEI 241
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
7-230 9.29e-23

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 96.06  E-value: 9.29e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP-----KMLAQK 81
Cdd:PRK11607   20 LEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPyqrpiNMMFQS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IALLAQssehplgMTVEEVVSYG----RYPYQKFFSGLNEedlhaiqwALEATQLTKLKERELSSLSGGQAQRVWIAMAL 157
Cdd:PRK11607  100 YALFPH-------MTVEQNIAFGlkqdKLPKAEIASRVNE--------MLGLVHMQEFAKRKPHQLSGGQRQRVALARSL 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 158 AQEADILILDEPTTFLDPA----HQLEILHLLKEINhikqTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK11607  165 AKRPKLLLLDEPMGALDKKlrdrMQLEVVDILERVG----VTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
6-226 9.73e-23

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 93.54  E-value: 9.73e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStYSPKMLAQKIALL 85
Cdd:COG4161     2 SIQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFD-FSQKPSEKAIRLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSsehpLGMTVEEvvsYGRYPYQKFFSGLNEEDL--------HAIQWA---LEATQLTKLKERELSSLSGGQAQRVWIA 154
Cdd:COG4161    81 RQK----VGMVFQQ---YNLWPHLTVMENLIEAPCkvlglskeQAREKAmklLARLRLTDKADRFPLHLSGGQQQRVAIA 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 155 MALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGT 226
Cdd:COG4161   154 RALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVT-HEVEFARKVASQVVYMEKGRIIEQGD 224
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
2-233 1.10e-22

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 94.97  E-value: 1.10e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   2 KNLTtieaVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP----VKEGKIIVDGSEISTYSP-- 75
Cdd:COG4170     7 RNLT----IEIDTPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKdnwhVTADRFRWNGIDLLKLSPre 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  76 --KMLAQKIALLAQ---SSEHP---LGMTVEEVVSYGRYPyQKFFSGLNEEDLHAIQWaleatqLTK--LKERE--LSS- 142
Cdd:COG4170    83 rrKIIGREIAMIFQepsSCLDPsakIGDQLIEAIPSWTFK-GKWWQRFKWRKKRAIEL------LHRvgIKDHKdiMNSy 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 143 ---LSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAG 219
Cdd:COG4170   156 pheLTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCG 235

                         250
                  ....*....|....
gi 1560390145 220 QIVVQGTPDEVITT 233
Cdd:COG4170   236 QTVESGPTEQILKS 249
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
7-249 1.25e-22

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 94.49  E-value: 1.25e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMlAQKIALLA 86
Cdd:PRK13537    8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHA-RQRVGVVP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTV-EEVVSYGRYpyqkffSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:PRK13537   87 QFDNLDPDFTVrENLLVFGRY------FGLSAAAARAlVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEInHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTswmreiyEIEA 244
Cdd:PRK13537  161 VLDEPTTGLDPQARHLMWERLRSL-LARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHALIES-------EIGC 232


                  ....*
gi 1560390145 245 QIIEL 249
Cdd:PRK13537  233 DVIEI 237
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 6-229 1.48e-22

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 96.45  E-value: 1.48e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVD-ITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVkEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:PRK11174  349 TIEAEDlEILSPDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPY-QGSLKINGIELRELDPESWRKHLSW 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHPLGmTVEEVVSYGRypyqkffSGLNEEDLHAiqwALEATQL------------TKLKERElSSLSGGQAQRVW 152
Cdd:PRK11174  428 VGQNPQLPHG-TLRDNVLLGN-------PDASDEQLQQ---ALENAWVseflpllpqgldTPIGDQA-AGLSVGQAQRLA 495

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 153 IAMALAQEADILILDEPTTFLDpAH--QLeILHLLKEINHiKQTTiLMSIHDINHASRFSDYLIgMKAGQIVVQGTPDE 229
Cdd:PRK11174  496 LARALLQPCQLLLLDEPTASLD-AHseQL-VMQALNAASR-RQTT-LMVTHQLEDLAQWDQIWV-MQDGQIVQQGDYAE 569
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 21-265 1.82e-22

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 94.15  E-value: 1.82e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKI----IVDGSEISTYSP------------KMLAQKIAL 84
Cdd:PRK13631   41 ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdIYIGDKKNNHELitnpyskkiknfKELRRRVSM 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHPL-GMTVEEVVSYGRYPYqkffsGLNEEDLHAiqwaLEATQLTKLK------ERELSSLSGGQAQRVWIAMAL 157
Cdd:PRK13631  121 VFQFPEYQLfKDTIEKDIMFGPVAL-----GVKKSEAKK----LAKFYLNKMGlddsylERSPFGLSGGQKRRVAIAGIL 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 158 AQEADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTswmR 237
Cdd:PRK13631  192 AIQPEILIFDEPTAGLDPKGEHEMMQLILDAKA-NNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTPYEIFTD---Q 267

                         250       260
                  ....*....|....*....|....*...
gi 1560390145 238 EIYEIEAqiIELPetnkPVVlsyDLIND 265
Cdd:PRK13631  268 HIINSTS--IQVP----RVI---QVIND 286
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 19-224 2.38e-22

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 92.95  E-value: 2.38e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP---KMLAQKIALLAQSSEHPLG- 94
Cdd:TIGR02769  24 APVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRkqrRAFRRDVQLVFQDSPSAVNp 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 -MTVEEVVsygRYPYQKFFSGLNEEDLHAIQWALEATQL-TKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:TIGR02769 104 rMTVRQII---GEPLRHLTSLDESEQKARIAELLDMVGLrSEDADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVSN 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 173 LDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQ 224
Cdd:TIGR02769 181 LDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIVEE 232
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 29-232 3.36e-22

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 94.01  E-value: 3.36e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  29 IPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseistyspKML---AQKIALLAqsseH--PLG--------- 94
Cdd:COG4148    22 LPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGG--------EVLqdsARGIFLPP----HrrRIGyvfqearlf 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 --MTVEEVVSYGRypyqKF-FSGLNEEDLHAIqwaLEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:COG4148    90 phLSVRGNLLYGR----KRaPRAERRISFDEV---VELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLA 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 172 FLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:COG4148   163 ALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLAEVLS 223
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 26-230 4.58e-22

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 95.14  E-value: 4.58e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPvKEGKIIVDGSEISTYSPKmlaqkiALLAQSSE------HPLG----- 94
Cdd:COG4172   306 SLTLRRGETLGLVGESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGLSRR------ALRPLRRRmqvvfqDPFGslspr 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 MTVEEVVSYGRYPYQKffsGLNEEDLHA-IQWALEATQLTK-LKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:COG4172   379 MTVGQIIAEGLRVHGP---GLSAAERRArVAEALEEVGLDPaARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSA 455

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 173 LDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:COG4172   456 LDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQV 513
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 7-199 4.75e-22

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 89.97  E-value: 4.75e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA 86
Cdd:cd03246     3 VENVSFRYPGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDHVGYLP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEhplgmtveevvsygrypyqkFFSGLNEEDLhaiqwaleatqltklkerelssLSGGQAQRVWIAMALAQEADILIL 166
Cdd:cd03246    83 QDDE--------------------LFSGSIAENI----------------------LSGGQRQRLGLARALYGNPRILVL 120

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKQTTILMS 199
Cdd:cd03246   121 DEPNSHLDVEGERALNQAIAALKAAGATRIVIA 153
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 19-227 5.50e-22

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 95.47  E-value: 5.50e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTySPKMLAQKIALLAQSSEHPLGMTVE 98
Cdd:TIGR01257  943 RPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIET-NLDAVRQSLGMCPQHNILFHHLTVA 1021

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   99 EVVSYgrypYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQ 178
Cdd:TIGR01257 1022 EHILF----YAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSR 1097

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1560390145  179 LEILHLLkeINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTP 227
Cdd:TIGR01257 1098 RSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 7-233 5.69e-22

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 92.08  E-value: 5.69e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPV-----KEGKIIVDGSEISTYSPKM-LAQ 80
Cdd:PRK14271   22 MAAVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKvsgyrYSGDVLLGGRSIFNYRDVLeFRR 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 KIALLAQSSeHPLGMTVEEVVSYGRYPYQ----KFFSGLNEEDLHAIQ-WALEATQLTKLKERelssLSGGQAQRVWIAM 155
Cdd:PRK14271  102 RVGMLFQRP-NPFPMSIMDNVLAGVRAHKlvprKEFRGVAQARLTEVGlWDAVKDRLSDSPFR----LSGGQQQLLCLAR 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 156 ALAQEADILILDEPTTFLDPAHQLEILHLLKEInhIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITT 233
Cdd:PRK14271  177 TLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSL--ADRLTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSS 252
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 29-214 6.40e-22

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 91.32  E-value: 6.40e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  29 IPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStYSPkmlaQKIallaqSSEHPlgMTVEEvvsygrypy 108
Cdd:cd03237    22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS-YKP----QYI-----KADYE--GTVRD--------- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 109 qkFFSGLNEEDLHAIQWALEAT---QLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLL 185
Cdd:cd03237    81 --LLSSITKDFYTHPYFKTEIAkplQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVI 158

                         170       180
                  ....*....|....*....|....*....
gi 1560390145 186 KEINHIKQTTILMSIHDINHASRFSDYLI 214
Cdd:cd03237   159 RRFAENNEKTAFVVEHDIIMIDYLADRLI 187
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 1-230 7.26e-22

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 91.33  E-value: 7.26e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLTTIEAVDITTGylNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPkmlaQ 80
Cdd:PRK09544    1 MTSLVSLENVSVSFG--QRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGYVP----Q 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 KIALLAQssehpLGMTVEEvvsygrypYQKFFSGLNEEDlhaIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:PRK09544   75 KLYLDTT-----LPLTVNR--------FLRLRPGTKKED---ILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNR 138

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKaGQIVVQGTPDEV 230
Cdd:PRK09544  139 PQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLN-HHICCSGTPEVV 207
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 6-228 7.74e-22

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 91.23  E-value: 7.74e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStYSPKMLAQKIALL 85
Cdd:PRK11124    2 SIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFD-FSKTPSDKAIREL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSsehpLGMTVEEvvsYGRYPYQKFF----------SGLNEEDlhAIQWA---LEATQLTKLKERELSSLSGGQAQRVW 152
Cdd:PRK11124   81 RRN----VGMVFQQ---YNLWPHLTVQqnlieapcrvLGLSKDQ--ALARAeklLERLRLKPYADRFPLHLSGGQQQRVA 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAHQLEILHLLKEinhIKQTTILMSI--HDINHASRFSDYLIGMKAGQIVVQGTPD 228
Cdd:PRK11124  152 IARALMMEPQVLLFDEPTAALDPEITAQIVSIIRE---LAETGITQVIvtHEVEVARKTASRVVYMENGHIVEQGDAS 226
galliderm_ABC TIGR03740
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ...
 7-229 1.20e-21

gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.


Pssm-ID: 163452 [Multi-domain]  Cd Length: 223  Bit Score: 90.15  E-value: 1.20e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEistYSPKMLaqkialla 86
Cdd:TIGR03740   1 LETKNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHP---WTRKDL-------- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 qsseHPLGMTVEEVVSYGRYPYQ---KFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADI 163
Cdd:TIGR03740  70 ----HKIGSLIESPPLYENLTARenlKVHTTLLGLPDSRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKL 145

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 164 LILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:TIGR03740 146 LILDEPTNGLDPIGIQELRELIRSFPE-QGITVILSSHILSEVQQLADHIGIISEGVLGYQGKINK 210
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 21-225 1.22e-21

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 89.96  E-value: 1.22e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPLGmTVEEV 100
Cdd:cd03245    19 ALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIGYVPQDVTLFYG-TLRDN 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYGRyPYQKffsglNEEDLHAIQWAlEATQLTKLK----ERELS----SLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:cd03245    98 ITLGA-PLAD-----DERILRAAELA-GVTDFVNKHpnglDLQIGergrGLSGGQRQAVALARALLNDPPILLLDEPTSA 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 173 LDPAHQLEILHLLKEInhIKQTTILMSIHdinhasRFS-----DYLIGMKAGQIVVQG 225
Cdd:cd03245   171 MDMNSEERLKERLRQL--LGDKTLIIITH------RPSlldlvDRIIVMDSGRIVADG 220
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 21-227 1.27e-21

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 89.86  E-value: 1.27e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQssehplgmtvEEV 100
Cdd:cd03244    19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSRISIIPQ----------DPV 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VsygrypyqkfFSG--------LNEEDLHAIQWALEATQL------------TKLKERElSSLSGGQAQRVWIAMALAQE 160
Cdd:cd03244    89 L----------FSGtirsnldpFGEYSDEELWQALERVGLkefveslpggldTVVEEGG-ENLSVGQRQLLCLARALLRK 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEinHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTP 227
Cdd:cd03244   158 SKILVLDEATASVDPETDALIQKTIRE--AFKDCTVLTIAHRLDTIID-SDRILVLDKGRVVEFDSP 221
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
7-259 1.60e-21

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 93.16  E-value: 1.60e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK--------ML 78
Cdd:COG1129     5 LEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRdaqaagiaII 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  79 AQKIALLAQssehplgMTVEEVVSYGRYPYQKFFsgLNEEDLHAiqwalEATQ-LTKLK-----ERELSSLSGGQAQRVW 152
Cdd:COG1129    85 HQELNLVPN-------LSVAENIFLGREPRRGGL--IDWRAMRR-----RARElLARLGldidpDTPVGDLSVAQQQLVE 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAhqlEILHLLKEINHIKQ--TTILMSIHDINHASRFSDYLIGMKAGQIVVQG----- 225
Cdd:COG1129   151 IARALSRDARVLILDEPTASLTER---EVERLFRIIRRLKAqgVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGpvael 227

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1560390145 226 TPDEVITtsWM--ReiyEIEAQIIELPETNKPVVLS 259
Cdd:COG1129   228 TEDELVR--LMvgR---ELEDLFPKRAAAPGEVVLE 258
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 4-240 2.64e-21

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 89.57  E-value: 2.64e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   4 LTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStyspkmlaqkIA 83
Cdd:PRK10895    1 MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDIS----------LL 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  84 LLAQSSEHPLGMTVEEVVSYGRYP-YQKFFSGLN-EEDLHAIQWALEATQL------TKLKERELSSLSGGQAQRVWIAM 155
Cdd:PRK10895   71 PLHARARRGIGYLPQEASIFRRLSvYDNLMAVLQiRDDLSAEQREDRANELmeefhiEHLRDSMGQSLSGGERRRVEIAR 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 156 ALAQEADILILDEPTTFLDPahqLEILHLLKEINHIKQT--TILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITT 233
Cdd:PRK10895  151 ALAANPKFILLDEPFAGVDP---ISVIDIKRIIEHLRDSglGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQD 227


                  ....*..
gi 1560390145 234 SWMREIY 240
Cdd:PRK10895  228 EHVKRVY 234
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 6-240 3.63e-21

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 89.32  E-value: 3.63e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQK-IAL 84
Cdd:COG1137     3 TLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRARLgIGY 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQssEHPL--GMTVEE----VVSYGRYPYQKffsglNEEDLHAIqwaLEATQLTKLKERELSSLSGGQAQRVWIAMALA 158
Cdd:COG1137    83 LPQ--EASIfrKLTVEDnilaVLELRKLSKKE-----REERLEEL---LEEFGITHLRKSKAYSLSGGERRRVEIARALA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 159 QEADILILDEPTTFLDPAHQLEILHLlkeINHIKQTTI--LMSIHD-------INHAsrfsdYLIgmKAGQIVVQGTPDE 229
Cdd:COG1137   153 TNPKFILLDEPFAGVDPIAVADIQKI---IRHLKERGIgvLITDHNvretlgiCDRA-----YII--SEGKVLAEGTPEE 222

                         250
                  ....*....|.
gi 1560390145 230 VITTSWMREIY 240
Cdd:COG1137   223 ILNNPLVRKVY 233
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 19-233 8.72e-21

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 91.31  E-value: 8.72e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK-----EGKIIVDGSEISTYSPKMLAQ----KIALLAQ-- 87
Cdd:PRK15134   22 RTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPpvvypSGDIRFHGESLLHASEQTLRGvrgnKIAMIFQep 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 -SSEHPLgMTVE----EVVSYGRypyqkffsGLNEEDLHA-IQWALEATQLTKLKEReLS----SLSGGQAQRVWIAMAL 157
Cdd:PRK15134  102 mVSLNPL-HTLEkqlyEVLSLHR--------GMRREAARGeILNCLDRVGIRQAAKR-LTdyphQLSGGERQRVMIAMAL 171

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 158 AQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITT 233
Cdd:PRK15134  172 LTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSA 247
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
 6-232 1.25e-20

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 90.87  E-value: 1.25e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:TIGR01842 318 SVENVTIVPPGGKKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKHIGYL 397

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPLGMTVEEVVSYGRYP-YQKFFSGLNEEDLHAIQWALEATQLTKLKERElSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:TIGR01842 398 PQDVELFPGTVAENIARFGENAdPEKIIEAAKLAGVHELILRLPDGYDTVIGPGG-ATLSGGQRQRIALARALYGDPKLV 476

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINhASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:TIGR01842 477 VLDEPNSNLDEEGEQALANAIKALKARGITVVVIT-HRPS-LLGCVDKILVLQDGRIARFGERDEVLA 542
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 7-231 1.33e-20

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 90.95  E-value: 1.33e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGY-LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALL 85
Cdd:TIGR01193 474 IVINDVSYSYgYGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLRQFINYL 553

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPLGMTVEEVVSYGRypyqkffSGLNEEDLHA------IQWALEATQL---TKLKErELSSLSGGQAQRVWIAMA 156
Cdd:TIGR01193 554 PQEPYIFSGSILENLLLGAK-------ENVSQDEIWAaceiaeIKDDIENMPLgyqTELSE-EGSSISGGQKQRIALARA 625

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 157 LAQEADILILDEPTTFLDPAHQLEILHLLKEINHikqTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:TIGR01193 626 LLTDSKVLILDESTSNLDTITEKKIVNNLLNLQD---KTIIFVAHRLSVAKQ-SDKIIVLDHGKIIEQGSHDELL 696
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 2-225 3.87e-20

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 85.30  E-value: 3.87e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   2 KNLTTieAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFT--RLLPVKEGKIIVDGSEIStysPKMLA 79
Cdd:cd03213     7 RNLTV--TVKSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAgrRTGLGVSGEVLINGRPLD---KRSFR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  80 QKIALLAQSSEHPLGMTVEEVVSYgrypyqkffsglneedlHAiqwaleatqltklkerELSSLSGGQAQRVWIAMALAQ 159
Cdd:cd03213    82 KIIGYVPQDDILHPTLTVRETLMF-----------------AA----------------KLRGLSGGERKRVSIALELVS 128

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 160 EADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINhASRFS--DYLIGMKAGQIVVQG 225
Cdd:cd03213   129 NPSLLFLDEPTSGLDSSSALQVMSLLRRLAD-TGRTIICSIHQPS-SEIFElfDKLLLLSQGRVIYFG 194
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 24-261 6.85e-20

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 87.47  E-value: 6.85e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  24 KMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKML----AQKIALLAQSSEHPLGMTVEE 99
Cdd:TIGR02142  15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGIFlppeKRRIGYVFQEARLFPHLSVRG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 VVSYGRypyqKFFSGlneeDLHAIQWA--LEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAH 177
Cdd:TIGR02142  95 NLRYGM----KRARP----SERRISFErvIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPR 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 178 QLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQIIelpetNKPVV 257
Cdd:TIGR02142 167 KYEILPYLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASPDLPWLAREDQGSL-----IEGVV 241


                  ....
gi 1560390145 258 LSYD 261
Cdd:TIGR02142 242 AEHD 245
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 26-229 8.79e-20

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 88.34  E-value: 8.79e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSsehplgmTV------EE 99
Cdd:COG5265   378 SFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASLRAAIGIVPQD-------TVlfndtiAY 450

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 VVSYGRyPyqkffsGLNEEDLHAiqwALEATQL------------TKLKERELsSLSGGQAQRVWIAMALAQEADILILD 167
Cdd:COG5265   451 NIAYGR-P------DASEEEVEA---AARAAQIhdfieslpdgydTRVGERGL-KLSGGEKQRVAIARTLLKNPPILIFD 519

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 168 EPTTFLDPAHQLEILHLLKEI--NHikqTTILmsihdINHasRFS-----DYLIGMKAGQIVVQGTPDE 229
Cdd:COG5265   520 EATSALDSRTERAIQAALREVarGR---TTLV-----IAH--RLStivdaDEILVLEAGRIVERGTHAE 578
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
19-222 9.74e-20

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 85.89  E-value: 9.74e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYS---PKMLAQKIALLAQSSehpLGM 95
Cdd:PRK10419   25 QTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNraqRKAFRRDIQMVFQDS---ISA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 -----TVEEVVsygRYPYQKFFSgLNEED-LHAIQWALEATQLT-KLKERELSSLSGGQAQRVWIAMALAQEADILILDE 168
Cdd:PRK10419  102 vnprkTVREII---REPLRHLLS-LDKAErLARASEMLRAVDLDdSVLDKRPPQLSGGQLQRVCLARALAVEPKLLILDE 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 169 PTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIV 222
Cdd:PRK10419  178 AVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIV 231
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
12-240 1.30e-19

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 84.93  E-value: 1.30e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  12 ITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTY-SPKMLAQKIALLAQSSE 90
Cdd:PRK11614   11 VSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWqTAKIMREAVAIVPEGRR 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  91 HPLGMTVEEVVSYGrypyqKFFSGlNEEDLHAIQWALEAtqLTKLKERELS---SLSGGQAQRVWIAMALAQEADILILD 167
Cdd:PRK11614   91 VFSRMTVEENLAMG-----GFFAE-RDQFQERIKWVYEL--FPRLHERRIQragTMSGGEQQMLAIGRALMSQPRLLLLD 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 168 EPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIY 240
Cdd:PRK11614  163 EPSLGLAPIIIQQIFDTIEQLRE-QGMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLANEAVRSAY 234
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 18-233 1.63e-19

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 87.84  E-value: 1.63e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPvKEGKIIVDGSEISTYSPK-MLA--QKIALLAQ---SSEH 91
Cdd:PRK15134  298 HNVVVKNISFTLRPGETLGLVGESGSGKSTTGLALLRLIN-SQGEIWFDGQPLHNLNRRqLLPvrHRIQVVFQdpnSSLN 376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  92 PLgMTVEEVVSYGRYPYQKFFSGLNEEDlHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:PRK15134  377 PR-LNVLQIIEEGLRVHQPTLSAAQREQ-QVIAVMEEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTS 454

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 172 FLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVITT 233
Cdd:PRK15134  455 SLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAA 516
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 18-231 1.94e-19

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 87.50  E-value: 1.94e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEhpL--Gm 95
Cdd:COG4618   344 KRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREELGRHIGYLPQDVE--LfdG- 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 TVEEVVSygRYPyqkffsglnEEDLHAIqwaLEATQL---------------TKLKEReLSSLSGGQAQRVWIAMALAQE 160
Cdd:COG4618   421 TIAENIA--RFG---------DADPEKV---VAAAKLagvhemilrlpdgydTRIGEG-GARLSGGQRQRIGLARALYGD 485

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 161 ADILILDEPTTFLDPA-HQleilHLLKEINHIKQ---TTILMSiHD---INHAsrfsDYLIGMKAGQIVVQGTPDEVI 231
Cdd:COG4618   486 PRLVVLDEPNSNLDDEgEA----ALAAAIRALKArgaTVVVIT-HRpslLAAV----DKLLVLRDGRVQAFGPRDEVL 554
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 28-227 2.38e-19

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 87.15  E-value: 2.38e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  28 KIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDgSEIStYSPKMLAQKIallaqssehplGMTVEEVVSygRYP 107
Cdd:COG1245   362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDED-LKIS-YKPQYISPDY-----------DGTVEEFLR--SAN 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 108 YQKFFSGLNEEDLhaiqwaLEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKE 187
Cdd:COG1245   427 TDDFGSSYYKTEI------IKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRR 500

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1560390145 188 INHIKQTTILMSIHDInhasrfsdYLIGMKAGQIVV-QGTP 227
Cdd:COG1245   501 FAENRGKTAMVVDHDI--------YLIDYISDRLMVfEGEP 533
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
6-231 2.68e-19

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 86.94  E-value: 2.68e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNK-QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:PRK13657  334 AVEFDDVSFSYDNSrQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRRNIAV 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSehplGM---TVEEVVSYGRypyqkffSGLNEEDLHAiqwALEATQLTKLKEREL-----------SSLSGGQAQR 150
Cdd:PRK13657  414 VFQDA----GLfnrSIEDNIRVGR-------PDATDEEMRA---AAERAQAHDFIERKPdgydtvvgergRQLSGGERQR 479

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 151 VWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILmsihdinhASRFS-----DYLIGMKAGQIVVQG 225
Cdd:PRK13657  480 LAIARALLKDPPILILDEATSALDVETEAKVKAALDELMKGRTTFII--------AHRLStvrnaDRILVFDNGRVVESG 551


                  ....*.
gi 1560390145 226 TPDEVI 231
Cdd:PRK13657  552 SFDELV 557
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
19-222 3.60e-19

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 84.14  E-value: 3.60e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK--MLAQKIALLaqssehPLgMT 96
Cdd:COG4525    20 QPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGADrgVVFQKDALL------PW-LN 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  97 VEEVVSYG-RypyqkfFSGLNEEDLHAIqwALEATQLTKLK---ERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:COG4525    93 VLDNVAFGlR------LRGVPKAERRAR--AEELLALVGLAdfaRRRIWQLSGGMRQRVGIARALAADPRFLLMDEPFGA 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 173 LDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKA--GQIV 222
Cdd:COG4525   165 LDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVMSPgpGRIV 216
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 26-230 4.56e-19

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 86.23  E-value: 4.56e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKM-LAQKIALLAQsseHPL---GMTVEEVV 101
Cdd:COG3845    25 SLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRDaIALGIGMVHQ---HFMlvpNLTVAENI 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 102 SYGRYPYQKFFSGLNEedlhAIQWALEATQLTKLK---ERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAhq 178
Cdd:COG3845   102 VLGLEPTKGGRLDRKA----ARARIRELSERYGLDvdpDAKVEDLSVGEQQRVEILKALYRGARILILDEPTAVLTPQ-- 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 179 lEILHLLKEINHIKQ--TTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:COG3845   176 -EADELFEILRRLAAegKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAET 228
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
6-230 6.71e-19

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 83.31  E-value: 6.71e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTY----------SP 75
Cdd:COG4598     8 ALEVRDLHKSFGDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKpdrdgelvpaDR 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  76 KMLAQ---KIALLAQSS---EHplgMTVEEVVSYGryPYQKFfsGLNEEDlhAIQWA---LEATQLTKLKERELSSLSGG 146
Cdd:COG4598    88 RQLQRirtRLGMVFQSFnlwSH---MTVLENVIEA--PVHVL--GRPKAE--AIERAealLAKVGLADKRDAYPAHLSGG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 147 QAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGT 226
Cdd:COG4598   159 QQQRAAIARALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEEGRTMLVVT-HEMGFARDVSSHVVFLHQGRIEEQGP 237


                  ....
gi 1560390145 227 PDEV 230
Cdd:COG4598   238 PAEV 241
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 18-201 1.35e-18

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 81.46  E-value: 1.35e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKmlaqkiallaqSSEHPLG--- 94
Cdd:PRK13539   14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVA-----------EACHYLGhrn 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 -----MTVEEVVSygrypyqkFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEP 169
Cdd:PRK13539   83 amkpaLTVAENLE--------FWAAFLGGEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEP 154

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1560390145 170 TTFLDPAHQLEILHLLKEinHIKQ-TTILMSIH 201
Cdd:PRK13539  155 TAALDAAAVALFAELIRA--HLAQgGIVIAATH 185
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 7-187 1.36e-18

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 84.73  E-value: 1.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVdGSEIstyspkmlaqKIALLA 86
Cdd:COG0488   316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV----------KIGYFD 384

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEH-PLGMTVEEVVSYGRypyqkffSGLNEEDLHAIqwaLEA------TQLTKLKerelsSLSGGQAQRVWIAMALAQ 159
Cdd:COG0488   385 QHQEElDPDKTVLDELRDGA-------PGGTEQEVRGY---LGRflfsgdDAFKPVG-----VLSGGEKARLALAKLLLS 449

                         170       180
                  ....*....|....*....|....*...
gi 1560390145 160 EADILILDEPTTFLDpahqLEILHLLKE 187
Cdd:COG0488   450 PPNVLLLDEPTNHLD----IETLEALEE 473
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 26-220 1.38e-18

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 81.36  E-value: 1.38e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSeistyspkmlaqkIALLAQSSEHpLGMTVEEVVSYGr 105
Cdd:cd03250    25 NLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS-------------IAYVSQEPWI-QNGTIRENILFG- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 106 YPYqkffsglNEEDLHAiqwALEATQLTK----LKERELS-------SLSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:cd03250    90 KPF-------DEERYEK---VIKACALEPdleiLPDGDLTeigekgiNLSGGQKQRISLARAVYSDADIYLLDDPLSAVD 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 175 P---AHQLE--ILHLLKeinhiKQTTILMSIHDINHASRFsDYLIGMKAGQ 220
Cdd:cd03250   160 AhvgRHIFEncILGLLL-----NNKTRILVTHQLQLLPHA-DQIVVLDNGR 204
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 22-225 1.63e-18

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 82.44  E-value: 1.63e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP----VKEGKIIVDGSEISTYSPKmlAQKIALLAQ---SSEHPL- 93
Cdd:PRK10418   19 VHGVSLTLQRGRVLALVGGSGSGKSLTCAAALGILPagvrQTAGRVLLDGKPVAPCALR--GRKIATIMQnprSAFNPLh 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 GMT---VEEVVSYGRYPyqkffsglneeDLHAIQWALEATQLTKlKERELSS----LSGGQAQRVWIAMALAQEADILIL 166
Cdd:PRK10418   97 TMHthaRETCLALGKPA-----------DDATLTAALEAVGLEN-AARVLKLypfeMSGGMLQRMMIALALLCEAPFIIA 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:PRK10418  165 DEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQG 223
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
6-226 2.19e-18

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 84.38  E-value: 2.19e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLN-KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:PRK10790  340 RIDIDNVSFAYRDdNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQGVAM 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSsehP--LGMTVEEVVSYGRypyqkffsGLNEEDLhaiqW-ALEATQLTKLKeRELS------------SLSGGQAQ 149
Cdd:PRK10790  420 VQQD---PvvLADTFLANVTLGR--------DISEEQV----WqALETVQLAELA-RSLPdglytplgeqgnNLSVGQKQ 483

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 150 RVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHdinhasRFS-----DYLIGMKAGQIVVQ 224
Cdd:PRK10790  484 LLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVR--EHTTLVVIAH------RLStiveaDTILVLHRGQAVEQ 555


                  ..
gi 1560390145 225 GT 226
Cdd:PRK10790  556 GT 557
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 22-219 4.59e-18

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 80.59  E-value: 4.59e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP-KMLA-QKIALLA-QSSEHPLGMTVE 98
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPdRMVVfQNYSLLPwLTVRENIALAVD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  99 EVVSYGRYPYQKffsglneedlHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQ 178
Cdd:TIGR01184  81 RVLPDLSKSERR----------AIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTR 150

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1560390145 179 LEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAG 219
Cdd:TIGR01184 151 GNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
 26-230 6.14e-18

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 81.70  E-value: 6.14e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP---KMLAQKIALLAQ---SSEHPlGMTVEE 99
Cdd:COG4608    38 SFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGrelRPLRRRMQMVFQdpyASLNP-RMTVGD 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 VVS-------------------------------YGRYPYQkffsglneedlhaiqwaleatqltklkerelssLSGGQA 148
Cdd:COG4608   117 IIAeplrihglaskaerrervaellelvglrpehADRYPHE---------------------------------FSGGQR 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 149 QRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPD 228
Cdd:COG4608   164 QRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPRD 243


                  ..
gi 1560390145 229 EV 230
Cdd:COG4608   244 EL 245
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
29-227 1.24e-17

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 82.16  E-value: 1.24e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  29 IPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDgSEIStYSPkmlaQKIallaqSSEHPlgMTVEEVVSYgrypy 108
Cdd:PRK13409  362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE-LKIS-YKP----QYI-----KPDYD--GTVEDLLRS----- 423

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 109 qkffsglNEEDLHAIQWALEAT---QLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLL 185
Cdd:PRK13409  424 -------ITDDLGSSYYKSEIIkplQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAI 496

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1560390145 186 KEINHIKQTTILMSIHDInhasrfsdYLIGMKAGQIVV-QGTP 227
Cdd:PRK13409  497 RRIAEEREATALVVDHDI--------YMIDYISDRLMVfEGEP 531
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 19-225 1.78e-17

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 78.73  E-value: 1.78e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseistyspkmlaqKIALL--AQSSEHPlGMT 96
Cdd:cd03220    35 FWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRG-------------RVSSLlgLGGGFNP-ELT 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  97 VEE-VVSYGRypyqkfFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:cd03220   101 GREnIYLNGR------LLGLSRKEIDEkIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALEPDILLIDEVLAVGD 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 175 PAHQLEILHLLKEInhIKQ-TTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:cd03220   175 AAFQEKCQRRLREL--LKQgKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
18-257 1.93e-17

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 81.68  E-value: 1.93e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQS----SEhpl 93
Cdd:PRK10789  327 DHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVSQTpflfSD--- 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 gmTVEEVVSYGRyPyqkffSGLNEEDLHAIQWA--------LEATQLTKLKERELSsLSGGQAQRVWIAMALAQEADILI 165
Cdd:PRK10789  404 --TVANNIALGR-P-----DATQQEIEHVARLAsvhddilrLPQGYDTEVGERGVM-LSGGQKQRISIARALLLNAEILI 474

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKEINhiKQTTILMSIHDINHASRFSDYLIgMKAGQIVVQGTPDEVITTS-WMREIY---E 241
Cdd:PRK10789  475 LDDALSAVDGRTEHQILHNLRQWG--EGRTVIISAHRLSALTEASEILV-MQHGHIAQRGNHDQLAQQSgWYRDMYryqQ 551

                         250
                  ....*....|....*.
gi 1560390145 242 IEAQIIELPETNKPVV 257
Cdd:PRK10789  552 LEAALDDAPEIREEAV 567
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
1-233 2.50e-17

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 80.23  E-value: 2.50e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLTtieaVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRL----LPVKEGKIIVDGSEISTYSP- 75
Cdd:PRK15093    6 IRNLT----IEFKTSDGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVtkdnWRVTADRMRFDDIDLLRLSPr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  76 ---KMLAQKIALLAQSSEHPL------GMTVEEVV---SY-GRYpYQKFfsglneedlhaiQW----ALEATQLTKLKER 138
Cdd:PRK15093   82 errKLVGHNVSMIFQEPQSCLdpservGRQLMQNIpgwTYkGRW-WQRF------------GWrkrrAIELLHRVGIKDH 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 139 E--LSS----LSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDY 212
Cdd:PRK15093  149 KdaMRSfpyeLTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADK 228

                         250       260
                  ....*....|....*....|.
gi 1560390145 213 LIGMKAGQIVVQGTPDEVITT 233
Cdd:PRK15093  229 INVLYCGQTVETAPSKELVTT 249
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 21-201 2.92e-17

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 77.78  E-value: 2.92e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKmLAQKIALLAQSSEHPLGMTVEEV 100
Cdd:TIGR01189  15 LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDE-PHENILYLGHLPGLKPELSALEN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYgrypYQKFFSGlneEDLhAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLE 180
Cdd:TIGR01189  94 LHF----WAAIHGG---AQR-TIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVAL 165

                         170       180
                  ....*....|....*....|..
gi 1560390145 181 ILHLLKEinHI-KQTTILMSIH 201
Cdd:TIGR01189 166 LAGLLRA--HLaRGGIVLLTTH 185
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 6-229 3.02e-17

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 77.91  E-value: 3.02e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGylNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK---EGKIIVDGSEISTYSPkmLAQKI 82
Cdd:COG4136     3 SLENLTITLG--GRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRLTALPA--EQRRI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  83 ALLAQSS---EHplgMTVEEVVSYGRYPyqkffsGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALA 158
Cdd:COG4136    79 GILFQDDllfPH---LSVGENLAFALPP------TIGRAQRRArVEQALEEAGLAGFADRDPATLSGGQRARVALLRALL 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 159 QEADILILDEPTTFLDPAHQLEILHLLKEinHIKQTTI--LMSIHDINHASrfsdyligmKAGQIVVQGTPDE 229
Cdd:COG4136   150 AEPRALLLDEPFSKLDAALRAQFREFVFE--QIRQRGIpaLLVTHDEEDAP---------AAGRVLDLGNWQH 211
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 31-213 4.12e-17

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 78.56  E-value: 4.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  31 EGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKI--------IVD---GSEISTYSPKMLAQKIallaqssehplgmtveE 99
Cdd:cd03236    25 EGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFddppdwdeILDefrGSELQNYFTKLLEGDV----------------K 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 VVSYGRYPYQ--KFFSGLNEE------DLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:cd03236    89 VIVKPQYVDLipKAVKGKVGEllkkkdERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSS 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1560390145 172 FLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYL 213
Cdd:cd03236   169 YLDIKQRLNAARLIRELAEDDNYVLVVE-HDLAVLDYLSDYI 209
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
12-222 5.70e-17

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 77.61  E-value: 5.70e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  12 ITTGYLN-KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK---MLAQKIALLAQ 87
Cdd:PRK10908    7 VSKAYLGgRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNRevpFLRRQIGMIFQ 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 ssEHPLGMtveEVVSYGRYPYQKFFSGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:PRK10908   87 --DHHLLM---DRTVYDNVAIPLIIAGASGDDIRRrVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLA 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKqTTILMSIHDINHASRFSDYLIGMKAGQIV 222
Cdd:PRK10908  162 DEPTGNLDDALSEGILRLFEEFNRVG-VTVLMATHDIGLISRRSYRMLTLSDGHLH 216
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
26-230 7.56e-17

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 80.17  E-value: 7.56e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKsftrLLP----VKEGKIIVDGSEIStySPK---MLAQKIALLAQSsehpLG---- 94
Cdd:NF033858   21 SLDIPAGCMVGLIGPDGVGKSSLLS----LIAgarkIQQGRVEVLGGDMA--DARhrrAVCPRIAYMPQG----LGknly 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 --MTVEEVVSygrypyqkFFS---GLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDE 168
Cdd:NF033858   91 ptLSVFENLD--------FFGrlfGQDAAERRRrIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDE 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 169 PTTFLDPAH-----QLeilhllkeINHIKQT----TILMSIHDINHASRFsDYLIGMKAGQIVVQGTPDEV 230
Cdd:NF033858  163 PTTGVDPLSrrqfwEL--------IDRIRAErpgmSVLVATAYMEEAERF-DWLVAMDAGRVLATGTPAEL 224
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
6-230 7.80e-17

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 79.12  E-value: 7.80e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNK-QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-----MLA 79
Cdd:PRK11650    3 GLKLQAVRKSYDGKtQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPAdrdiaMVF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  80 QKIALLAqsseHplgMTVEEVVSYG---RypyqkffsGLNEEDLHA-IQWALEATQLTKLKERELSSLSGGQAQRVwiAM 155
Cdd:PRK11650   83 QNYALYP----H---MSVRENMAYGlkiR--------GMPKAEIEErVAEAARILELEPLLDRKPRELSGGQRQRV--AM 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 156 --ALAQEADILILDEPTTFLDP----AHQLEILHLLKEINhikqTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:PRK11650  146 grAIVREPAVFLFDEPLSNLDAklrvQMRLEIQRLHRRLK----TTSLYVTHDQVEAMTLADRVVVMNGGVAEQIGTPVE 221


                  .
gi 1560390145 230 V 230
Cdd:PRK11650  222 V 222
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
15-226 2.19e-16

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 76.01  E-value: 2.19e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  15 GYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLA----QKIALLAQSSE 90
Cdd:PRK11629   18 GSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAelrnQKLGFIYQFHH 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  91 HPLGMTVEEVVSY-----GRYPYQkffsglneedlhAIQWALE---ATQLTKLKERELSSLSGGQAQRVWIAMALAQEAD 162
Cdd:PRK11629   98 LLPDFTALENVAMplligKKKPAE------------INSRALEmlaAVGLEHRANHRPSELSGGERQRVAIARALVNNPR 165

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 163 ILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLiGMKAGQIVVQGT 226
Cdd:PRK11629  166 LVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQL-EMRDGRLTAELS 228
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 19-231 2.62e-16

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 75.89  E-value: 2.62e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSeIStyspkmlaqkiALLA-QSSEHP----- 92
Cdd:COG1134    39 FWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGR-VS-----------ALLElGAGFHPeltgr 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  93 ---------LGMTVEEVvsygrypYQKF-----FSGLnEEDLHaiqwaleatqlTKLKerelsSLSGGQAQRVWIAMALA 158
Cdd:COG1134   107 eniylngrlLGLSRKEI-------DEKFdeiveFAEL-GDFID-----------QPVK-----TYSSGMRARLAFAVATA 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 159 QEADILILDEPTTFLDPAHQLEILHLLKEInhIKQ-TTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:COG1134   163 VDPDILLVDEVLAVGDAAFQKKCLARIREL--RESgRTVIFVSHSMGAVRRLCDRAIWLEKGRLVMDGDPEEVI 234
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 7-214 2.63e-16

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 73.64  E-value: 2.63e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEistyspkmlaqKIALLA 86
Cdd:cd03221     1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTV-----------KIGYFE 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QssehplgmtveevvsygrypyqkffsglneedlhaiqwaleatqltklkerelssLSGGQAQRVWIAMALAQEADILIL 166
Cdd:cd03221    70 Q-------------------------------------------------------LSGGEKMRLALAKLLLENPNLLLL 94

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1560390145 167 DEPTTFLDPAHqleILHLLKEINHIKQTTILMSiHDINHASRFSDYLI 214
Cdd:cd03221    95 DEPTNHLDLES---IEALEEALKEYPGTVILVS-HDRYFLDQVATKII 138
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 19-232 5.76e-16

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 77.46  E-value: 5.76e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFT----RLLPVKEGKIIVDGseistYSP-KMLAQKIALLAQSSE--- 90
Cdd:TIGR00956   74 FDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIAsntdGFHIGVEGVITYDG-----ITPeEIKKHYRGDVVYNAEtdv 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   91 HPLGMTVEEVVSYG---RYPyQKFFSGLNEE-------DLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:TIGR00956  149 HFPHLTVGETLDFAarcKTP-QNRPDGVSREeyakhiaDVYMATYGLSHTRNTKVGNDFVRGVSGGERKRVSIAEASLGG 227

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145  161 ADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINH-ASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:TIGR00956  228 AKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQCSQdAYELFDKVIVLYEGYQIYFGPADKAKQ 300
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 7-176 9.11e-16

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 73.68  E-value: 9.11e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKmLAQKIALLA 86
Cdd:cd03231     1 LEADELTCERDGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDS-IARGLLYLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVsygrypyqKFFSGLNEEDlhAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:cd03231    80 HAPGIKTTLSVLENL--------RFWHADHSDE--QVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWIL 149

                         170
                  ....*....|
gi 1560390145 167 DEPTTFLDPA 176
Cdd:cd03231   150 DEPTTALDKA 159
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
21-229 9.26e-16

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 76.22  E-value: 9.26e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  21 VIEK-MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-----MLAQKIALLAQssehplg 94
Cdd:PRK11000   17 VISKdINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAergvgMVFQSYALYPH------- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 MTVEEVVSYGrypyQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:PRK11000   90 LSVAENMSFG----LKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLD 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 175 PA----HQLEILHLLKEInhikQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:PRK11000  166 AAlrvqMRIEISRLHKRL----GRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLE 220
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 20-227 9.82e-16

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 73.60  E-value: 9.82e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  20 QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPLGMTVEE 99
Cdd:cd03369    22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTIIPQDPTLFSGTIRSN 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 VVSYGRYPYQKFFSGLneedlhaiqwaleatqltKLKERELsSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQL 179
Cdd:cd03369   102 LDPFDEYSDEEIYGAL------------------RVSEGGL-NLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDA 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1560390145 180 EILHLLKEinHIKQTTILMSIHDINHASRFsDYLIGMKAGQIVVQGTP 227
Cdd:cd03369   163 LIQKTIRE--EFTNSTILTIAHRLRTIIDY-DKILVMDAGEVKEYDHP 207
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 2-206 1.41e-15

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 73.59  E-value: 1.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   2 KNLTTIEAVDITTGylNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQK 81
Cdd:PRK10247    5 SPLLQLQNVGYLAG--DAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  82 IALLAQSsehP--LGMTVEEVVSygrYPYQ---------KFFSGLneedlhaIQWALEATQLTKlkerELSSLSGGQAQR 150
Cdd:PRK10247   83 VSYCAQT---PtlFGDTVYDNLI---FPWQirnqqpdpaIFLDDL-------ERFALPDTILTK----NIAELSGGEKQR 145

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 151 VWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHD---INHA 206
Cdd:PRK10247  146 ISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDkdeINHA 204
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
 10-219 1.44e-15

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 73.52  E-value: 1.44e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  10 VDITTGYL----NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGS-EISTYSPKMLAQKIAL 84
Cdd:cd03290     1 VQVTNGYFswgsGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKnESEPSFEATRSRNRYS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHP--LGMTVEEVVSYGR-YPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSsLSGGQAQRVWIAMALAQEA 161
Cdd:cd03290    81 VAYAAQKPwlLNATVEENITFGSpFNKQRYKAVTDACSLQPDIDLLPFGDQTEIGERGIN-LSGGQRQRICVARALYQNT 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 162 DILILDEPTTFLD---PAHQLE--ILHLLKEinhiKQTTILMSIHDINHASRfSDYLIGMKAG 219
Cdd:cd03290   160 NIVFLDDPFSALDihlSDHLMQegILKFLQD----DKRTLVLVTHKLQYLPH-ADWIIAMKDG 217
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 26-222 1.46e-15

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 73.62  E-value: 1.46e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAqkiALLAQS------SEHPLG-MTVE 98
Cdd:COG4181    32 SLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARA---RLRARHvgfvfqSFQLLPtLTAL 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  99 EVVsygrypyqkffsGLNEE---DLHAIQWALEATQLTKLKEREL---SSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:COG4181   109 ENV------------MLPLElagRRDARARARALLERVGLGHRLDhypAQLSGGEQQRVALARAFATEPAILFADEPTGN 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1560390145 173 LDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIV 222
Cdd:COG4181   177 LDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRAGRLV 225
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 22-230 1.89e-15

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 74.78  E-value: 1.89e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP----VKEGKIIVDGSEISTYSPK----MLAQKIALLAQ---SSE 90
Cdd:PRK11022   23 VDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDypgrVMAEKLEFNGQDLQRISEKerrnLVGAEVAMIFQdpmTSL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  91 HP---LGMTVEEVVsygrypyqKFFSGLNEEDLHaiQWALEATQLTKLKERELS------SLSGGQAQRVWIAMALAQEA 161
Cdd:PRK11022  103 NPcytVGFQIMEAI--------KVHQGGNKKTRR--QRAIDLLNQVGIPDPASRldvyphQLSGGMSQRVMIAMAIACRP 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 162 DILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK11022  173 KLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDI 241
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
7-239 2.12e-15

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 75.59  E-value: 2.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQ-KIALL 85
Cdd:PRK09700    6 ISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQlGIGII 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPLGMTVEEVVSYGRYPYQKFFsGLNEEDLHAI-QWALEATQLTKLK---ERELSSLSGGQAQRVWIAMALAQEA 161
Cdd:PRK09700   86 YQELSVIDELTVLENLYIGRHLTKKVC-GVNIIDWREMrVRAAMMLLRVGLKvdlDEKVANLSISHKQMLEIAKTLMLDA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 162 DILILDEPTTFLDpahQLEILHLLKEINHIKQ--TTILMSIHDINHASRFSDYLIGMKAGQIVVQG-----TPDEVITTS 234
Cdd:PRK09700  165 KVIIMDEPTSSLT---NKEVDYLFLIMNQLRKegTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGmvsdvSNDDIVRLM 241


                  ....*
gi 1560390145 235 WMREI 239
Cdd:PRK09700  242 VGREL 246
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 19-229 2.36e-15

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 75.47  E-value: 2.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP---VKEGKIIVDGSEIStySPKMlaQKIALLAQSSEHPLGM 95
Cdd:TIGR00955  38 KHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPkgvKGSGSVLLNGMPID--AKEM--RAISAYVQQDDLFIPT 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 -TVEEVVSY------GRYPYQKffsglneEDLHAIQWALEATQLTKLK------ERELSSLSGGQAQRVWIAMALAQEAD 162
Cdd:TIGR00955 114 lTVREHLMFqahlrmPRRVTKK-------EKRERVDEVLQALGLRKCAntrigvPGRVKGLSGGERKRLAFASELLTDPP 186

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 163 ILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHD-INHASRFSDYLIGMKAGQIVVQGTPDE 229
Cdd:TIGR00955 187 LLFCDEPTSGLDSFMAYSVVQVLKGLAQ-KGKTIICTIHQpSSELFELFDKIILMAEGRVAYLGSPDQ 253
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 28-230 2.44e-15

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 74.38  E-value: 2.44e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  28 KIPEGKVTS---------------LIGPNGSGKSTLLKSFTRLLpVKEGKI----IVDGSEISTYSPKML----AQKIAL 84
Cdd:PRK09473   23 STPDGDVTAvndlnfslragetlgIVGESGSGKSQTAFALMGLL-AANGRIggsaTFNGREILNLPEKELnklrAEQISM 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQ---SSEHP---LGMTVEEVVS-YGRYPYQKFFsglnEED---LHAIQWAlEATQLTKLKERELSslsGGQAQRVWIA 154
Cdd:PRK09473  102 IFQdpmTSLNPymrVGEQLMEVLMlHKGMSKAEAF----EESvrmLDAVKMP-EARKRMKMYPHEFS---GGMRQRVMIA 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 155 MALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK09473  174 MALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDV 249
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 6-197 2.61e-15

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 75.23  E-value: 2.61e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGylNKQV-IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVdgseistysPKmlAQKIAL 84
Cdd:COG4178   364 ALEDLTLRTP--DGRPlLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIAR---------PA--GARVLF 430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHPLGmTVEEVVSYgryPYQKffSGLNEEDLHAiqwALEATQLTKLKEReLSS-------LSGGQAQRVWIAMAL 157
Cdd:COG4178   431 LPQRPYLPLG-TLREALLY---PATA--EAFSDAELRE---ALEAVGLGHLAER-LDEeadwdqvLSLGEQQRLAFARLL 500

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1560390145 158 AQEADILILDEPTTFLDPAHQLEILHLLKEinHIKQTTIL 197
Cdd:COG4178   501 LHKPDWLFLDEATSALDEENEAALYQLLRE--ELPGTTVI 538
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 7-254 6.15e-15

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 74.07  E-value: 6.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSF--TRLLPVKEGKII-------------------- 64
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLrgMDQYEPTSGRIIyhvalcekcgyverpskvge 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  65 -------------VDGSEISTYSPKMLAQKIALLAQSSehpLGMTVEEVVsygrypYQKFFSGLNE---EDLHAIQWALE 128
Cdd:TIGR03269  81 pcpvcggtlepeeVDFWNLSDKLRRRIRKRIAIMLQRT---FALYGDDTV------LDNVLEALEEigyEGKEAVGRAVD 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 129 ATQLTKLKEREL---SSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPaHQLEILH-LLKEINHIKQTTILMSIHDIN 204
Cdd:TIGR03269 152 LIEMVQLSHRIThiaRDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDP-QTAKLVHnALEEAVKASGISMVLTSHWPE 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 205 HASRFSDYLIGMKAGQIVVQGTPDEVITTsWMR--------EIYEIEAQIIELPETNK 254
Cdd:TIGR03269 231 VIEDLSDKAIWLENGEIKEEGTPDEVVAV-FMEgvsevekeCEVEVGEPIIKVRNVSK 287
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 26-230 8.50e-15

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 72.82  E-value: 8.50e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQK---IALLAQSsehPLG-----MTV 97
Cdd:PRK15079   41 TLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVrsdIQMIFQD---PLAslnprMTI 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  98 EEVVSYgryPYQKFFSGLNEEDLHAIQWA--LEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDP 175
Cdd:PRK15079  118 GEIIAE---PLRTYHPKLSRQEVKDRVKAmmLKVGLLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDV 194

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 176 AHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK15079  195 SIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEV 249
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
16-206 1.78e-14

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 71.27  E-value: 1.78e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  16 YLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK--MLAQKIALLAQSSehpl 93
Cdd:PRK11248   11 YGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAErgVVFQNEGLLPWRN---- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 gmtVEEVVSYGRYpyqkfFSGL-NEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:PRK11248   87 ---VQDNVAFGLQ-----LAGVeKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGA 158

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1560390145 173 LDPAHQLEILHLLKEINHIKQTTILMSIHDINHA 206
Cdd:PRK11248  159 LDAFTREQMQTLLLKLWQETGKQVLLITHDIEEA 192
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 7-174 2.50e-14

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 72.28  E-value: 2.50e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVdGSEIstyspkmlaqKIALLA 86
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETV----------KLAYVD 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEH--PlGMTVEEVVSYG-------------RYPYQKF-FSGlneedlhaiqwaleATQLTKLKErelssLSGGQAQR 150
Cdd:TIGR03719 392 QSRDAldP-NKTVWEEISGGldiiklgkreipsRAYVGRFnFKG--------------SDQQKKVGQ-----LSGGERNR 451

                         170       180
                  ....*....|....*....|....
gi 1560390145 151 VWIAMALAQEADILILDEPTTFLD 174
Cdd:TIGR03719 452 VHLAKTLKSGGNVLLLDEPTNDLD 475
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
31-174 6.39e-14

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 71.38  E-value: 6.39e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  31 EGKVTSLIGPNGSGKSTLLKSFT-RLLP-----VKEGKI--IVD---GSEISTYSPKM------LAQKIALLAQSSEHPL 93
Cdd:PRK13409   98 EGKVTGILGPNGIGKTTAVKILSgELIPnlgdyEEEPSWdeVLKrfrGTELQNYFKKLyngeikVVHKPQYVDLIPKVFK 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  94 GmTVEEVVSygRYPYQKFFSGLNEEdlhaiqwaLEatqLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFL 173
Cdd:PRK13409  178 G-KVRELLK--KVDERGKLDEVVER--------LG---LENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYL 243


                  .
gi 1560390145 174 D 174
Cdd:PRK13409  244 D 244
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 31-174 6.69e-14

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 70.97  E-value: 6.69e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  31 EGKVTSLIGPNGSGKSTLLKSFTRLL---------PVKEGKII--VDGSEISTYSPKMLAQKIallaqssehplgmtveE 99
Cdd:COG1245    98 KGKVTGILGPNGIGKSTALKILSGELkpnlgdydeEPSWDEVLkrFRGTELQDYFKKLANGEI----------------K 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 VVSYGRYPYQ--KFFSGlNEEDLhaiqwaLEATQ-------------LTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:COG1245   162 VAHKPQYVDLipKVFKG-TVREL------LEKVDergkldelaeklgLENILDRDISELSGGELQRVAIAAALLRDADFY 234

                         170
                  ....*....|
gi 1560390145 165 ILDEPTTFLD 174
Cdd:COG1245   235 FFDEPSSYLD 244
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
12-242 8.48e-14

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 70.71  E-value: 8.48e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  12 ITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-MLAQKIALLAQSSE 90
Cdd:PRK11288   10 IGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTaALAAGVAIIYQELH 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  91 HPLGMTVEEVVSYGRYPYQkfFSGLNEEDLhaIQWALEatQLTKLKER-----ELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:PRK11288   90 LVPEMTVAENLYLGQLPHK--GGIVNRRLL--NYEARE--QLEHLGVDidpdtPLKYLSIGQRQMVEIAKALARNARVIA 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 166 LDEPTTFLDpahQLEILHLLKEINHIKQ--TTILMSIHDINHASRFSDYLIGMKAGQIV-----VQGTP-DEVITTSWMR 237
Cdd:PRK11288  164 FDEPTSSLS---AREIEQLFRVIRELRAegRVILYVSHRMEEIFALCDAITVFKDGRYVatfddMAQVDrDQLVQAMVGR 240


                  ....*
gi 1560390145 238 EIYEI 242
Cdd:PRK11288  241 EIGDI 245
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 1-239 9.69e-14

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 70.73  E-value: 9.69e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLT----TIEAVDittgylnkqvieKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK--EGKIIVDGSEISTYS 74
Cdd:PRK13549    8 MKNITktfgGVKALD------------NVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGtyEGEIIFEGEELQASN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  75 PKMLAQK-IALLAQSSEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWaLEATQLTKLKERELSSLSGGQAQRVWI 153
Cdd:PRK13549   76 IRDTERAgIAIIHQELALVKELSVLENIFLGNEITPGGIMDYDAMYLRAQKL-LAQLKLDINPATPVGNLGLGQQQLVEI 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 154 AMALAQEADILILDEPTTFLDPAhqlEILHLLKEINHIKQ---TTILMSiHDINHASRFSDYLIGMKAGQIV-----VQG 225
Cdd:PRK13549  155 AKALNKQARLLILDEPTASLTES---ETAVLLDIIRDLKAhgiACIYIS-HKLNEVKAISDTICVIRDGRHIgtrpaAGM 230

                         250
                  ....*....|....
gi 1560390145 226 TPDEVITTSWMREI 239
Cdd:PRK13549  231 TEDDIITMMVGREL 244
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 14-225 1.45e-13

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 70.27  E-value: 1.45e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  14 TGYLNK-----QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP---KMLAQKIALL 85
Cdd:PRK10261  327 SGLLNRvtrevHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPgklQALRRDIQFI 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSS------EHPLGMTVEEvvsygryPYQKFFSGLNEEDLHAIQWALEATQLtkLKE---RELSSLSGGQAQRVWIAMA 156
Cdd:PRK10261  407 FQDPyasldpRQTVGDSIME-------PLRVHGLLPGKAAAARVAWLLERVGL--LPEhawRYPHEFSGGQRQRICIARA 477

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 157 LAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQG 225
Cdd:PRK10261  478 LALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 22-231 2.17e-13

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 69.45  E-value: 2.17e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKII-------VDGSEISTYSPKMLAQKIALLAQSsehplg 94
Cdd:TIGR03269 300 VDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNvrvgdewVDMTKPGPDGRGRAKRYIGILHQE------ 373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 mtveevvsYGRYPYQKFFSGLNEE------DLHAIQWA---LEATQLTKLKEREL-----SSLSGGQAQRVWIAMALAQE 160
Cdd:TIGR03269 374 --------YDLYPHRTVLDNLTEAiglelpDELARMKAvitLKMVGFDEEKAEEIldkypDELSEGERHRVALAQVLIKE 445

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILH-LLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:TIGR03269 446 PRIVILDEPTGTMDPITKVDVTHsILKAREEMEQTFIIVS-HDMDFVLDVCDRAALMRDGKIVKIGDPEEIV 516
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 18-225 2.38e-13

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 66.90  E-value: 2.38e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK---EGKIIVDGSEISTYSPKMLAQkIALLAQSSEHPLG 94
Cdd:cd03233    19 KIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEKYPGE-IIYVSEEDVHFPT 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 MTVEEVVSygrypyqkfFSglneedlhaiqwaleatqlTKLKERE-LSSLSGGQAQRVWIAMALAQEADILILDEPTTFL 173
Cdd:cd03233    98 LTVRETLD---------FA-------------------LRCKGNEfVRGISGGERKRVSIAEALVSRASVLCWDNSTRGL 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 174 DPAHQLEILHLLKEINHIKQTTILMSIH----DINHAsrFsDYLIGMKAGQIVVQG 225
Cdd:cd03233   150 DSSTALEILKCIRTMADVLKTTTFVSLYqasdEIYDL--F-DKVLVLYEGRQIYYG 202
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 22-193 2.42e-13

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 69.37  E-value: 2.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-MLAQKIALLAQSSEHPLGMTVEEV 100
Cdd:PRK10982   14 LDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKeALENGISMVHQELNLVLQRSVMDN 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYGRYPYQKFFSGLNE--EDLHAIQWALEATQLTKLKereLSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDpahQ 178
Cdd:PRK10982   94 MWLGRYPTKGMFVDQDKmyRDTKAIFDELDIDIDPRAK---VATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLT---E 167

                         170
                  ....*....|....*
gi 1560390145 179 LEILHLLKEINHIKQ 193
Cdd:PRK10982  168 KEVNHLFTIIRKLKE 182
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 20-230 3.45e-13

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 69.11  E-value: 3.45e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  20 QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGS----------EISTYSPKML----AQKIALL 85
Cdd:PRK10261   30 AAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMllrrrsrqviELSEQSAAQMrhvrGADMAMI 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQ---SSEHPLgMTVEEVVSYGRYPYQkffsGLN-EEDLHAIQWALEATQLTKLKE---RELSSLSGGQAQRVWIAMALA 158
Cdd:PRK10261  110 FQepmTSLNPV-FTVGEQIAESIRLHQ----GASrEEAMVEAKRMLDQVRIPEAQTilsRYPHQLSGGMRQRVMIAMALS 184

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 159 QEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK10261  185 CRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQI 256
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 11-221 5.28e-13

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 67.01  E-value: 5.28e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  11 DITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLksftRLLPvkegkiivdGSEISTySPKMLAQKiALLAQSSE 90
Cdd:PRK11247   17 AVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLL----RLLA---------GLETPS-AGELLAGT-APLAEARE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  91 HPLGMTVEEVVsygrYPYQKFFS----GLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:PRK11247   82 DTRLMFQDARL----LPWKKVIDnvglGLKGQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLL 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQI 221
Cdd:PRK11247  158 DEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
PTZ00243 PTZ00243
ABC transporter; Provisional
 19-234 6.48e-13

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 68.65  E-value: 6.48e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSeistyspkmlaqkIALLAQSSeHPLGMTVE 98
Cdd:PTZ00243   673 KVLLRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAERS-------------IAYVPQQA-WIMNATVR 738

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   99 EVVSygrypyqkFFSGLNEEDLH-AIQWA-LEA--TQLTKLKERELS----SLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:PTZ00243   739 GNIL--------FFDEEDAARLAdAVRVSqLEAdlAQLGGGLETEIGekgvNLSGGQKARVSLARAVYANRDVYLLDDPL 810

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145  171 TFLDpAHQLEilHLLKE--INHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVITTS 234
Cdd:PTZ00243   811 SALD-AHVGE--RVVEEcfLGALAGKTRVLATHQVHVVPR-ADYVVALGDGRVEFSGSSADFMRTS 872
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 138-231 8.99e-13

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 68.12  E-value: 8.99e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 138 RELSSLSGGQAQRVWIAMALAQEAD---ILILDEPTT---FLDPAHQLEILHLLKEINHikqtTILMSIHDInHASRFSD 211
Cdd:TIGR00630 825 QPATTLSGGEAQRIKLAKELSKRSTgrtLYILDEPTTglhFDDIKKLLEVLQRLVDKGN----TVVVIEHNL-DVIKTAD 899

                          90       100
                  ....*....|....*....|....*.
gi 1560390145 212 YLI------GMKAGQIVVQGTPDEVI 231
Cdd:TIGR00630 900 YIIdlgpegGDGGGTVVASGTPEEVA 925
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 7-174 9.54e-13

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 67.84  E-value: 9.54e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVdGSEIstyspkmlaqKIALLA 86
Cdd:PRK11819  325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETV----------KLAYVD 393

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEH--PlGMTVEEVVSYG-------------RYPYQKF-FSGlneedlhaiqwaleATQLTKLKErelssLSGGQAQR 150
Cdd:PRK11819  394 QSRDAldP-NKTVWEEISGGldiikvgnreipsRAYVGRFnFKG--------------GDQQKKVGV-----LSGGERNR 453

                         170       180
                  ....*....|....*....|....
gi 1560390145 151 VWIAMALAQEADILILDEPTTFLD 174
Cdd:PRK11819  454 LHLAKTLKQGGNVLLLDEPTNDLD 477
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
 26-227 1.05e-12

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 66.10  E-value: 1.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLL-----KSFTRLLPVKEGK----------------IIVDGSEI--------STYS-- 74
Cdd:cd03271    15 DVDIPLGVLTCVTGVSGSGKSSLIndtlyPALARRLHLKKEQpgnhdrieglehidkvIVIDQSPIgrtprsnpATYTgv 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  75 ------------------PKMLAqkIALLAQSSEHPLGMTVEEVVsygrypyqKFFsgLNEEDLHAIQWALEATQLTKLK 136
Cdd:cd03271    95 fdeirelfcevckgkrynRETLE--VRYKGKSIADVLDMTVEEAL--------EFF--ENIPKIARKLQTLCDVGLGYIK 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 137 -ERELSSLSGGQAQRVWIAMALAQEAD---ILILDEPTT---FLDPAHQLEILHLLKEINHikqtTILMSIHDInHASRF 209
Cdd:cd03271   163 lGQPATTLSGGEAQRIKLAKELSKRSTgktLYILDEPTTglhFHDVKKLLEVLQRLVDKGN----TVVVIEHNL-DVIKC 237

                         250       260
                  ....*....|....*....|....
gi 1560390145 210 SDYLI------GMKAGQIVVQGTP 227
Cdd:cd03271   238 ADWIIdlgpegGDGGGQVVASGTP 261
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 12-239 1.42e-12

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 67.16  E-value: 1.42e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  12 ITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP--VKEGKIIVDGSEISTYSPKMLAQK-IALLAQS 88
Cdd:TIGR02633   7 IVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPhgTWDGEIYWSGSPLKASNIRDTERAgIVIIHQE 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  89 SEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKE-RELSSLSGGQAQRVWIAMALAQEADILILD 167
Cdd:TIGR02633  87 LTLVPELSVAENIFLGNEITLPGGRMAYNAMYLRAKNLLRELQLDADNVtRPVGDYGGGQQQLVEIAKALNKQARLLILD 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1560390145 168 EPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQG-----TPDEVITTSWMREI 239
Cdd:TIGR02633 167 EPSSSLTEKETEILLDIIRDLKAHGVACVYIS-HKLNEVKAVCDTICVIRDGQHVATKdmstmSEDDIITMMVGREI 242
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 26-187 1.43e-12

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 64.38  E-value: 1.43e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP-KMLAQKIALLAQS-SEHPL--GMTVEEVV 101
Cdd:cd03215    20 SFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPrDAIRAGIAYVPEDrKREGLvlDLSVAENI 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 102 SYGRYpyqkffsglneedlhaiqwaleatqltklkerelssLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEI 181
Cdd:cd03215   100 ALSSL------------------------------------LSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEI 143


                  ....*.
gi 1560390145 182 LHLLKE 187
Cdd:cd03215   144 YRLIRE 149
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 18-241 1.53e-12

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 64.86  E-value: 1.53e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLK------SFTrllpVKEGKIIVDGSEISTYSPKMLAQK-IALLAQSSE 90
Cdd:cd03217    12 GKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKtimghpKYE----VTEGEILFKGEDITDLPPEERARLgIFLAFQYPP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  91 HPLGMTVEEvvsygrypyqkFFSGLNEedlhaiqwaleatqltklkerelsSLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:cd03217    88 EIPGVKNAD-----------FLRYVNE------------------------GFSGGEKKRNEILQLLLLEPDLAILDEPD 132

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 171 TFLDpahqLEILHLL-KEINHIKQ--TTILMsihdINHASRFSDYLIG-----MKAGQIVVQGTPDEVittswmREIYE 241
Cdd:cd03217   133 SGLD----IDALRLVaEVINKLREegKSVLI----ITHYQRLLDYIKPdrvhvLYDGRIVKSGDKELA------LEIEK 197
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
20-235 2.54e-12

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 66.67  E-value: 2.54e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  20 QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQkiallaQSSEHpLGMTvee 99
Cdd:PRK10535   22 EVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQ------LRREH-FGFI--- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 100 vvsYGRYPYQKFFSGLNEEDLHAIQWALEATQ--------LTKL--KER---ELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:PRK10535   92 ---FQRYHLLSHLTAAQNVEVPAVYAGLERKQrllraqelLQRLglEDRveyQPSQLSGGQQQRVSIARALMNGGQVILA 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRfSDYLIGMKAGQIV----------VQGTPDEVITT--S 234
Cdd:PRK10535  169 DEPTGALDSHSGEEVMAILHQLRDRGHTVIIVT-HDPQVAAQ-AERVIEIRDGEIVrnppaqekvnVAGGTEPVVNTasG 246


                  .
gi 1560390145 235 W 235
Cdd:PRK10535  247 W 247
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 5-204 2.91e-12

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 65.49  E-value: 2.91e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   5 TTIEAVDittgylnkqvieKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseistYSP----KMLAQ 80
Cdd:COG4586    33 REVEAVD------------DISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLG-----YVPfkrrKEFAR 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  81 KIAL-LAQSSE----HPLGMTVE---EVvsYgRYPYQKFFSGLNE--EDLhaiqwaleatQLTKLKERELSSLSGGQAQR 150
Cdd:COG4586    96 RIGVvFGQRSQlwwdLPAIDSFRllkAI--Y-RIPDAEYKKRLDElvELL----------DLGELLDTPVRQLSLGQRMR 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 151 VWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDIN 204
Cdd:COG4586   163 CELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMD 216
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 26-221 3.25e-12

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 66.15  E-value: 3.25e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseistyspkmlaqkiallaqssehplgmtvEEVVSYGR 105
Cdd:PRK10522  343 NLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDG------------------------------KPVTAEQP 392

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 106 YPYQKFFS----------------GLNEEDLHAIQWaLEATQL---TKLKERELS--SLSGGQAQRVWIAMALAQEADIL 164
Cdd:PRK10522  393 EDYRKLFSavftdfhlfdqllgpeGKPANPALVEKW-LERLKMahkLELEDGRISnlKLSKGQKKRLALLLALAEERDIL 471

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 165 ILDEPTTFLDPAHQ----LEILHLLKEINHikqtTILMSIHDiNHASRFSDYLIGMKAGQI 221
Cdd:PRK10522  472 LLDEWAADQDPHFRrefyQVLLPLLQEMGK----TIFAISHD-DHYFIHADRLLEMRNGQL 527
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
93-231 3.42e-12

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 66.20  E-value: 3.42e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  93 LGMTVEEVVsygrypyqKFFsglneEDLHAIQWALEATQ---LTKLKereL----SSLSGGQAQRVWIAMALAQEAD--- 162
Cdd:COG0178   786 LDMTVEEAL--------EFF-----ENIPKIARKLQTLQdvgLGYIK---LgqpaTTLSGGEAQRVKLASELSKRSTgkt 849

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 163 ILILDEPTT---FLDPAHQLEILHLLKE-------INH----IKQttilmsihdinhasrfSDYLI------GMKAGQIV 222
Cdd:COG0178   850 LYILDEPTTglhFHDIRKLLEVLHRLVDkgntvvvIEHnldvIKT----------------ADWIIdlgpegGDGGGEIV 913


                  ....*....
gi 1560390145 223 VQGTPDEVI 231
Cdd:COG0178   914 AEGTPEEVA 922
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
26-231 5.03e-12

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 65.53  E-value: 5.03e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKI-----IVDGSEISTyspkmlAQKIALLAQSsehplgmtveev 100
Cdd:NF033858  286 SFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAwlfgqPVDAGDIAT------RRRVGYMSQA------------ 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 vsygrypyqkfFSgLNEE-------DLHA-------------IQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQE 160
Cdd:NF033858  348 -----------FS-LYGEltvrqnlELHArlfhlpaaeiaarVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHK 415

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:NF033858  416 PELLILDEPTSGVDPVARDMFWRLLIELSREDGVTIFISTHFMNEAER-CDRISLMHAGRVLASDTPAALV 485
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 32-192 7.62e-12

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 65.02  E-value: 7.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  32 GKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK--------MLAQKIALLAQssehplgMTVEEVVSY 103
Cdd:PRK10762   30 GRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKssqeagigIIHQELNLIPQ-------LTIAENIFL 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 104 GRYPYQKFfsglneedlHAIQWA---LEATQ-LTKLK-----ERELSSLSGGQAQRVWIAMALAQEADILILDEPTtflD 174
Cdd:PRK10762  103 GREFVNRF---------GRIDWKkmyAEADKlLARLNlrfssDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPT---D 170

                         170
                  ....*....|....*...
gi 1560390145 175 PAHQLEILHLLKEINHIK 192
Cdd:PRK10762  171 ALTDTETESLFRVIRELK 188
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 18-228 1.02e-11

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 63.16  E-value: 1.02e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSftrLL-----PVKEGKIIVDGSEISTYSPKMLAQK-IALLAQsseH 91
Cdd:COG0396    12 GKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKV---LMghpkyEVTSGSILLDGEDILELSPDERARAgIFLAFQ---Y 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  92 PL---GMTVEEVVsygRYPYQKffsgLNEEDLHAIQW---ALEATQLTKLKE----REL-SSLSGGQAQRVWIAMALAQE 160
Cdd:COG0396    86 PVeipGVSVSNFL---RTALNA----RRGEELSAREFlklLKEKMKELGLDEdfldRYVnEGFSGGEKKRNEILQMLLLE 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 161 ADILILDEPTTFLDpahqLEILHLLKE-INHI--KQTTILMsihdINHASRFSDYL-----IGMKAGQIVVQGTPD 228
Cdd:COG0396   159 PKLAILDETDSGLD----IDALRIVAEgVNKLrsPDRGILI----ITHYQRILDYIkpdfvHVLVDGRIVKSGGKE 226
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 25-231 1.07e-11

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 64.97  E-value: 1.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSeiSTYSPKMlaqkiALLAQSSehplgmtVEEVVSYG 104
Cdd:TIGR00957  657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS--VAYVPQQ-----AWIQNDS-------LRENILFG 722

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  105 RYPYQKFFSGLNEE-----DLHAiqwaLEATQLTKLKERELSsLSGGQAQRVWIAMALAQEADILILDEPTTFLDP---A 176
Cdd:TIGR00957  723 KALNEKYYQQVLEAcallpDLEI----LPSGDRTEIGEKGVN-LSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAhvgK 797

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145  177 HQLEilHLLKEINHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:TIGR00957  798 HIFE--HVIGPEGVLKNKTRILVTHGISYLPQ-VDVIIVMSGGKISEMGSYQELL 849
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 6-187 1.35e-11

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 61.40  E-value: 1.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGyLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEistyspkmlaqKIALL 85
Cdd:cd03223     2 ELENLSLATP-DGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEGE-----------DLLFL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  86 AQSSEHPLGmTVEEVVSygrYPYQKffsglneedlhaiqwaleatqltklkerelsSLSGGQAQRVWIAMALAQEADILI 165
Cdd:cd03223    70 PQRPYLPLG-TLREQLI---YPWDD-------------------------------VLSGGEQQRLAFARLLLHKPKFVF 114

                         170       180
                  ....*....|....*....|..
gi 1560390145 166 LDEPTTFLDPAHQLEILHLLKE 187
Cdd:cd03223   115 LDEATSALDEESEDRLYQLLKE 136
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 32-201 1.64e-11

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 61.88  E-value: 1.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  32 GKVTSLIGPNGSGKSTLLK--SFTRLLPVKEGKIIVDGSEIstysPKMLAQKIALLAQSSEHPLGMTVEEVVSygrypyq 109
Cdd:cd03232    33 GTLTALMGESGAGKTTLLDvlAGRKTAGVITGEILINGRPL----DKNFQRSTGYVEQQDVHSPNLTVREALR------- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 110 kfFSGLneedlhaiqwaleatqltklkereLSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEIN 189
Cdd:cd03232   102 --FSAL------------------------LRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKLA 155

                         170
                  ....*....|..
gi 1560390145 190 HIKQtTILMSIH 201
Cdd:cd03232   156 DSGQ-AILCTIH 166
PLN03232 PLN03232
ABC transporter C family member; Provisional
 21-232 2.08e-11

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 63.84  E-value: 2.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSehplgMTVEEV 100
Cdd:PLN03232  1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRVLSIIPQSP-----VLFSGT 1325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  101 VSYGRYPyqkfFSGLNEEDLhaiqW-ALEATQLTKLKER-------ELS----SLSGGQAQRVWIAMALAQEADILILDE 168
Cdd:PLN03232  1326 VRFNIDP----FSEHNDADL----WeALERAHIKDVIDRnpfgldaEVSeggeNFSVGQRQLLSLARALLRRSKILVLDE 1397

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145  169 PTTFLDPAHQLEILHLLKEinHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:PLN03232  1398 ATASVDVRTDSLIQRTIRE--EFKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLS 1458
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 32-230 2.21e-11

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 62.25  E-value: 2.21e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  32 GKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIV---DGSEISTYSpkMLAQKIALLAQSS-----EHP---LGMTVEev 100
Cdd:PRK11701   32 GEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYrmrDGQLRDLYA--LSEAERRRLLRTEwgfvhQHPrdgLRMQVS-- 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 vsygrypyqkffSGLN-EEDLHAIQW----ALEATQLTKLKEREL---------SSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:PRK11701  108 ------------AGGNiGERLMAVGArhygDIRATAGDWLERVEIdaariddlpTTFSGGMQQRLQIARNLVTHPRLVFM 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK11701  176 DEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLTDQV 239
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 22-221 2.99e-11

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 63.10  E-value: 2.99e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-MLAQKIALLAQSSEHP---LGMTV 97
Cdd:PRK10762  268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQdGLANGIVYISEDRKRDglvLGMSV 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  98 EEVVSYGRYPYQKFFSG-LNEEDLHaiQWALEATQLTKLK----ERELSSLSGGQAQRVWIAMALAQEADILILDEPTTF 172
Cdd:PRK10762  348 KENMSLTALRYFSRAGGsLKHADEQ--QAVSDFIRLFNIKtpsmEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRG 425

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 173 LDPAHQLEILHLlkeINHIKQ---TTILMSiHDINHASRFSDYLIGMKAGQI 221
Cdd:PRK10762  426 VDVGAKKEIYQL---INQFKAeglSIILVS-SEMPEVLGMSDRILVMHEGRI 473
3a01203 TIGR00954
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...
 21-189 3.25e-11

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 273360 [Multi-domain]  Cd Length: 659  Bit Score: 63.23  E-value: 3.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSeistyspkmlaQKIALLAQSSEHPLGmTVEEV 100
Cdd:TIGR00954 467 LIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAK-----------GKLFYVPQRPYMTLG-TLRDQ 534

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYGRYPYQKFFSGLNEEDLHAIqwaLEATQLTKLKERELS---------SLSGGQAQRVWIAMALAQEADILILDEPTT 171
Cdd:TIGR00954 535 IIYPDSSEDMKRRGLSDKDLEQI---LDNVQLTHILEREGGwsavqdwmdVLSGGEKQRIAMARLFYHKPQFAILDECTS 611

                         170
                  ....*....|....*...
gi 1560390145 172 FLDPAHQLEILHLLKEIN 189
Cdd:TIGR00954 612 AVSVDVEGYMYRLCREFG 629
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 32-208 3.70e-11

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 61.33  E-value: 3.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  32 GKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYS----PKMLAQKIALLAQSSehplgMTVEEVVSYGRYP 107
Cdd:PRK10584   36 GETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDeearAKLRAKHVGFVFQSF-----MLIPTLNALENVE 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 108 YQKFFSGlnEEDLHAIQWALEATQLTKLKEREL---SSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHL 184
Cdd:PRK10584  111 LPALLRG--ESSRQSRNGAKALLEQLGLGKRLDhlpAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADL 188

                         170       180
                  ....*....|....*....|....
gi 1560390145 185 LKEINHIKQTTILMSIHDINHASR 208
Cdd:PRK10584  189 LFSLNREHGTTLILVTHDLQLAAR 212
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
42-170 4.07e-11

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 62.73  E-value: 4.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  42 GSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPK-MLAQKIALLaqssehP---------LGMTVEEVVSYGRYPYQKF 111
Cdd:COG1129   288 GAGRTELARALFGADPADSGEIRLDGKPVRIRSPRdAIRAGIAYV------PedrkgeglvLDLSIRENITLASLDRLSR 361

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560390145 112 FSGLNEEDLHAIqwALEATQLTKLK----ERELSSLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:COG1129   362 GGLLDRRRERAL--AEEYIKRLRIKtpspEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPT 422
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 26-230 4.81e-11

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 61.90  E-value: 4.81e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP---KMLAQKIALLAQSsehPlgmtveevvs 102
Cdd:PRK11308   35 SFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPeaqKLLRQKIQIVFQN---P---------- 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 103 YGRY-PYQKFFSGLnEEDLhAIQWALEATQLtklKERELSSL-----------------SGGQAQRVWIAMALAQEADIL 164
Cdd:PRK11308  102 YGSLnPRKKVGQIL-EEPL-LINTSLSAAER---REKALAMMakvglrpehydryphmfSGGQRQRIAIARALMLDPDVV 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEV 230
Cdd:PRK11308  177 VADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQI 242
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 20-220 5.32e-11

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 60.91  E-value: 5.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  20 QVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSE----ISTYSPKmlaQKIALLaqssEHPLG- 94
Cdd:COG4778    25 PVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGgwvdLAQASPR---EILALR----RRTIGy 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 ----------MTVEEVVsygrypyqkffsglnEEDLHAIQWALEATQ------LTKL--KEReLSSL-----SGGQAQRV 151
Cdd:COG4778    98 vsqflrviprVSALDVV---------------AEPLLERGVDREEARararelLARLnlPER-LWDLppatfSGGEQQRV 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 152 WIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEinhIKQ--TTILMSIHDINHASRFSDYLIGMKAGQ 220
Cdd:COG4778   162 NIARGFIADPPLLLLDEPTASLDAANRAVVVELIEE---AKArgTAIIGIFHDEEVREAVADRVVDVTPFS 229
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 21-231 5.66e-11

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 62.66  E-value: 5.66e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPLGMTVEEV 100
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFKITIIPQDPVLFSGSLRMNL 1380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  101 VSYGRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKERElSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDpahqLE 180
Cdd:TIGR00957 1381 DPFSQYSDEEVWWALELAHLKTFVSALPDKLDHECAEGG-ENLSVGQRQLVCLARALLRKTKILVLDEATAAVD----LE 1455

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1560390145  181 ILHLLKEI--NHIKQTTILMSIHDINHASRFSDYLIgMKAGQIVVQGTPDEVI 231
Cdd:TIGR00957 1456 TDNLIQSTirTQFEDCTVLTIAHRLNTIMDYTRVIV-LDKGEVAEFGAPSNLL 1507
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 26-225 9.11e-11

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 60.35  E-value: 9.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTL----------------LKSFTRLLPVKEGKIIVDgsEISTYSPKM-LAQKiaLLAQS 88
Cdd:cd03270    15 DVDIPRNKLVVITGVSGSGKSSLafdtiyaegqrryvesLSAYARQFLGQMDKPDVD--SIEGLSPAIaIDQK--TTSRN 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  89 SEHPLGmTVEEVVSYGRYPYQKffSGLNEEDLHAIQWALEATQLtklkERELSSLSGGQAQRVWIAMALAQEAD--ILIL 166
Cdd:cd03270    91 PRSTVG-TVTEIYDYLRLLFAR--VGIRERLGFLVDVGLGYLTL----SRSAPTLSGGEAQRIRLATQIGSGLTgvLYVL 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHD---INHAsrfsDYLI------GMKAGQIVVQG 225
Cdd:cd03270   164 DEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVE-HDedtIRAA----DHVIdigpgaGVHGGEIVAQG 226
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 1-226 9.33e-11

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 60.43  E-value: 9.33e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   1 MKNLTTIEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLK------SFTrllpVKEGKIIVDGSEISTYS 74
Cdd:CHL00131    2 NKNKPILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKviaghpAYK----ILEGDILFKGESILDLE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  75 PKMLAQKIALLAqsSEHPL---GMTVEEVVSYGRYPYQKfFSGLNEED-LHAIQWALEATQLTKLKERELS-----SLSG 145
Cdd:CHL00131   78 PEERAHLGIFLA--FQYPIeipGVSNADFLRLAYNSKRK-FQGLPELDpLEFLEIINEKLKLVGMDPSFLSrnvneGFSG 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 146 GQAQRVWI-AMALAqEADILILDEPTTFLDpAHQLEILHllKEINHIKQTTilMSIHDINHASRFSDYLIG-----MKAG 219
Cdd:CHL00131  155 GEKKRNEIlQMALL-DSELAILDETDSGLD-IDALKIIA--EGINKLMTSE--NSIILITHYQRLLDYIKPdyvhvMQNG 228


                  ....*..
gi 1560390145 220 QIVVQGT 226
Cdd:CHL00131  229 KIIKTGD 235
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 1-192 1.13e-10

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 61.97  E-value: 1.13e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145    1 MKNLTTIEAVDITTGYLNKQVIE---KMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIV-DGSEISTYSPK 76
Cdd:PTZ00265   377 LKDIKKIQFKNVRFHYDTRKDVEiykDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIInDSHNLKDINLK 456

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   77 MLAQKIALLAQSsehPL--GMTVEEVVSYGRYPYQKF--------------FSGLNEE---------DLHAIQWALEATQ 131
Cdd:PTZ00265   457 WWRSKIGVVSQD---PLlfSNSIKNNIKYSLYSLKDLealsnyynedgndsQENKNKRnscrakcagDLNDMSNTTDSNE 533

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  132 LTKLKER-----------------------------------ELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDpa 176
Cdd:PTZ00265   534 LIEMRKNyqtikdsevvdvskkvlihdfvsalpdkyetlvgsNASKLSGGQKQRISIARAIIRNPKILILDEATSSLD-- 611

                          250
                   ....*....|....*.
gi 1560390145  177 HQLEILhLLKEINHIK 192
Cdd:PTZ00265   612 NKSEYL-VQKTINNLK 626
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 25-221 1.32e-10

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 61.22  E-value: 1.32e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKM-LAQKIALLA---QSS----EHPLGMT 96
Cdd:PRK15439  282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQrLARGLVYLPedrQSSglylDAPLAWN 361

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  97 VEEVVsYGRYPyqkFFsglneedlhaIQWALEATQLTKL----------KERELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:PRK15439  362 VCALT-HNRRG---FW----------IKPARENAVLERYrralnikfnhAEQAARTLSGGNQQKVLIAKCLEASPQLLIV 427

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 167 DEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHASRFSDYLIGMKAGQI 221
Cdd:PRK15439  428 DEPTRGVDVSARNDIYQLIRSIAA-QNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
uvrA PRK00349
excinuclease ABC subunit UvrA;
143-230 2.39e-10

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 60.86  E-value: 2.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 143 LSGGQAQRVWIAMALAQEAD---ILILDEPTT---FLDPAHQLEILHLLKE-------INH----IKQttilmsihdinh 205
Cdd:PRK00349  831 LSGGEAQRVKLAKELSKRSTgktLYILDEPTTglhFEDIRKLLEVLHRLVDkgntvvvIEHnldvIKT------------ 898

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1560390145 206 asrfSDYLI------GMKAGQIVVQGTPDEV 230
Cdd:PRK00349  899 ----ADWIIdlgpegGDGGGEIVATGTPEEV 925
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 29-174 2.79e-10

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 60.35  E-value: 2.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  29 IPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEI--------------STYSpkMLAQKIALLAQSSE--HP 92
Cdd:PRK11147   26 IEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIvarlqqdpprnvegTVYD--FVAEGIEEQAEYLKryHD 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  93 LGMTVEEvvsygrYPYQKFFSGLNE--EDL-HAIQWALEA---TQLTKLK---ERELSSLSGGQAQRVWIAMALAQEADI 163
Cdd:PRK11147  104 ISHLVET------DPSEKNLNELAKlqEQLdHHNLWQLENrinEVLAQLGldpDAALSSLSGGWLRKAALGRALVSNPDV 177

                         170
                  ....*....|.
gi 1560390145 164 LILDEPTTFLD 174
Cdd:PRK11147  178 LLLDEPTNHLD 188
PLN03232 PLN03232
ABC transporter C family member; Provisional
 7-179 3.50e-10

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 60.37  E-value: 3.50e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145    7 IEAVDITTGY------LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFT-RLLPVKEGKIIVDGSeiSTYSPKMla 79
Cdd:PLN03232   612 APAISIKNGYfswdskTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLgELSHAETSSVVIRGS--VAYVPQV-- 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   80 qkiallaqssEHPLGMTVEEVVSYG-RYPYQKFFSGLneeDLHAIQWALE---ATQLTKLKERELSsLSGGQAQRVWIAM 155
Cdd:PLN03232   688 ----------SWIFNATVRENILFGsDFESERYWRAI---DVTALQHDLDllpGRDLTEIGERGVN-ISGGQKQRVSMAR 753

                          170       180
                   ....*....|....*....|....*.
gi 1560390145  156 ALAQEADILILDEPTTFLDP--AHQL 179
Cdd:PLN03232   754 AVYSNSDIYIFDDPLSALDAhvAHQV 779
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 7-232 4.47e-10

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 60.04  E-value: 4.47e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145    7 IEAVDITTGYL---NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK------------------------ 59
Cdd:PTZ00265  1166 IEIMDVNFRYIsrpNVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLLMRFYDLKndhhivfknehtndmtneqdyqgd 1245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   60 ------------------------------EGKIIVDGSEISTYSPKMLAQKIALLAQsseHPL--GMTVEEVVSYGRyp 107
Cdd:PTZ00265  1246 eeqnvgmknvnefsltkeggsgedstvfknSGKILLDGVDICDYNLKDLRNLFSIVSQ---EPMlfNMSIYENIKFGK-- 1320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  108 yqkffSGLNEEDL-HAIQWALEATQLTKLKERELS-------SLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQL 179
Cdd:PTZ00265  1321 -----EDATREDVkRACKFAAIDEFIESLPNKYDTnvgpygkSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEK 1395

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145  180 EILHLLKEINHIKQTTILMSIHDINHASRfSDYLIGM----KAGQIV-VQGTPDEVIT 232
Cdd:PTZ00265  1396 LIEKTIVDIKDKADKTIITIAHRIASIKR-SDKIVVFnnpdRTGSFVqAHGTHEELLS 1452
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
 29-227 5.11e-10

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 57.20  E-value: 5.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  29 IPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStYSPkmlaQKIallaqssehplgmtveevvsygrypy 108
Cdd:cd03222    22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITPV-YKP----QYI-------------------------- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 109 qkffsglneedlhaiqwaleatqltklkerelsSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEI 188
Cdd:cd03222    71 ---------------------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRL 117

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1560390145 189 NHIKQTTILMSIHDINHASRFSDYLigmkagqIVVQGTP 227
Cdd:cd03222   118 SEEGKKTALVVEHDLAVLDYLSDRI-------HVFEGEP 149
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 22-225 7.41e-10

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 56.56  E-value: 7.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLksFTRLLPVKEGKIIvdgSEISTYSPkmlaQKIALLAQSSehplgmtveevv 101
Cdd:cd03238    11 LQNLDVSIPLNVLVVVTGVSGSGKSTLV--NEGLYASGKARLI---SFLPKFSR----NKLIFIDQLQ------------ 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 102 sygrypyqkffsglneedlhaiqwALEATQLTKLK-ERELSSLSGGQAQRVWIAMALAQEAD--ILILDEPTTFLdpaHQ 178
Cdd:cd03238    70 ------------------------FLIDVGLGYLTlGQKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGL---HQ 122

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 179 LEILHLLKEINHIKQ--TTILMSIHDINhASRFSDYLI------GMKAGQIVVQG 225
Cdd:cd03238   123 QDINQLLEVIKGLIDlgNTVILIEHNLD-VLSSADWIIdfgpgsGKSGGKVVFSG 176
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 11-203 7.76e-10

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 59.15  E-value: 7.76e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   11 DITTGYLN--KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVkEGKIIVDGSEISTYSPKMLAQKIALLAQS 88
Cdd:TIGR01271 1222 GLTAKYTEagRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLST-EGEIQIDGVSWNSVTLQTWRKAFGVIPQK 1300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   89 SEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIqwaLE--ATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILIL 166
Cdd:TIGR01271 1301 VFIFSGTFRKNLDPYEQWSDEEIWKVAEEVGLKSV---IEqfPDKLDFVLVDGGYVLSNGHKQLMCLARSILSKAKILLL 1377

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1560390145  167 DEPTTFLDPAHQLEILHLLKEinHIKQTTILMSIHDI 203
Cdd:TIGR01271 1378 DEPSAHLDPVTLQIIRKTLKQ--SFSNCTVILSEHRV 1412
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 22-226 8.97e-10

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 59.26  E-value: 8.97e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTyspkmlaqKIALLAQSSEH-PLGMTVEEV 100
Cdd:TIGR01257 1955 VDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILT--------NISDVHQNMGYcPQFDAIDDL 2026

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  101 VSyGR---YPYQKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAH 177
Cdd:TIGR01257 2027 LT-GRehlYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQA 2105

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1560390145  178 QLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGT 226
Cdd:TIGR01257 2106 RRMLWNTIVSIIREGRAVVLTS-HSMEECEALCTRLAIMVKGAFQCLGT 2153
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 26-222 1.34e-09

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 58.27  E-value: 1.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIStyspkmlaqkiallAQSSEHplgmtveevvsygr 105
Cdd:COG4615   352 DLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVT--------------ADNREA-------------- 403

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 106 ypYQKFFS-------------GLNEEDLHAI--QWaLEATQL---TKLKERELSS--LSGGQAQRVWIAMALAQEADILI 165
Cdd:COG4615   404 --YRQLFSavfsdfhlfdrllGLDGEADPARarEL-LERLELdhkVSVEDGRFSTtdLSQGQRKRLALLVALLEDRPILV 480

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 166 LDEPTtfldpAHQ---------LEILHLLKEINHikqtTILMSIHD---INHASRfsdyLIGMKAGQIV 222
Cdd:COG4615   481 FDEWA-----ADQdpefrrvfyTELLPELKARGK----TVIAISHDdryFDLADR----VLKMDYGKLV 536
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
132-237 1.80e-09

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 57.58  E-value: 1.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 132 LTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEIL----HLLKEINhikqTTILMSIHDINHAS 207
Cdd:PRK11144  118 IEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLpyleRLAREIN----IPILYVSHSLDEIL 193

                          90       100       110
                  ....*....|....*....|....*....|
gi 1560390145 208 RFSDYLIGMKAGQIVVQGTPDEVITTSWMR 237
Cdd:PRK11144  194 RLADRVVVLEQGKVKAFGPLEEVWASSAMR 223
sufC TIGR01978
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ...
 19-228 1.97e-09

FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 273907 [Multi-domain]  Cd Length: 243  Bit Score: 56.50  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFT--RLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA-QSSEHPLGM 95
Cdd:TIGR01978  13 KEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAghPSYEVTSGTILFKGQDLLELEPDERARAGLFLAfQYPEEIPGV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 TVEEVVsygRYPYQKFFSGLNEEDLHAIQWALEATQLTKLKE--RELSS------LSGGQAQRVWIAMALAQEADILILD 167
Cdd:TIGR01978  93 SNLEFL---RSALNARRSARGEEPLDLLDFEKLLKEKLALLDmdEEFLNrsvnegFSGGEKKRNEILQMALLEPKLAILD 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 168 EPTTFLDpAHQLEIlhLLKEINHIKQTTilMSIHDINHASRFSDYLIG-----MKAGQIVVQGTPD 228
Cdd:TIGR01978 170 EIDSGLD-IDALKI--VAEGINRLREPD--RSFLIITHYQRLLNYIKPdyvhvLLDGRIVKSGDVE 230
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 7-175 2.42e-09

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 56.12  E-value: 2.42e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA 86
Cdd:COG2401    31 LEAFGVELRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCVDVPDNQFGREASLIDAIGRKG 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEhplgmtVEEVVSYgrypyqkffSGLNEedlhAIQWaleatqLTKLKErelssLSGGQAQRVWIAMALAQEADILIL 166
Cdd:COG2401   111 DFKD------AVELLNA---------VGLSD----AVLW------LRRFKE-----LSTGQKFRFRLALLLAERPKLLVI 160


                  ....*....
gi 1560390145 167 DEPTTFLDP 175
Cdd:COG2401   161 DEFCSHLDR 169
PTZ00243 PTZ00243
ABC transporter; Provisional
 21-176 2.54e-09

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 57.87  E-value: 2.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPLGmTVEEV 100
Cdd:PTZ00243  1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLRELRRQFSMIPQDPVLFDG-TVRQN 1403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  101 VSygrypyqKFFSGLNEEdlhaiQWAleATQLTKLKERELSSLSG--------------GQAQRVWIAMALAQEADILIL 166
Cdd:PTZ00243  1404 VD-------PFLEASSAE-----VWA--ALELVGLRERVASESEGidsrvleggsnysvGQRQLMCMARALLKKGSGFIL 1469

                          170
                   ....*....|.
gi 1560390145  167 -DEPTTFLDPA 176
Cdd:PTZ00243  1470 mDEATANIDPA 1480
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 7-203 2.59e-09

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 56.40  E-value: 2.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLN--KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVkEGKIIVDGSEISTYSPKMLAQKIAL 84
Cdd:cd03289     3 MTVKDLTAKYTEggNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNT-EGDIQIDGVSWNSVPLQKWRKAFGV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEHPLGMTVEEVVSYGRYPYQKFFSGLNEEDLHAIQWALEAtQLTKLKERELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:cd03289    82 IPQKVFIFSGTFRKNLDPYGKWSDEEIWKVAEEVGLKSVIEQFPG-QLDFVLVDGGCVLSHGHKQLMCLARSVLSKAKIL 160

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEinHIKQTTILMSIHDI 203
Cdd:cd03289   161 LLDEPSAHLDPITYQVIRKTLKQ--AFADCTVILSEHRI 197
PLN03130 PLN03130
ABC transporter C family member; Provisional
 21-232 2.79e-09

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 57.44  E-value: 2.79e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   21 VIEKMSIKI-PEGKVtSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSehplgMTVEE 99
Cdd:PLN03130  1254 VLHGLSFEIsPSEKV-GIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKVLGIIPQAP-----VLFSG 1327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  100 VVSYGRYPyqkfFSGLNEEDLhaiqW-ALEATQLTKLKER-------ELS----SLSGGQAQRVWIAMALAQEADILILD 167
Cdd:PLN03130  1328 TVRFNLDP----FNEHNDADL----WeSLERAHLKDVIRRnslgldaEVSeageNFSVGQRQLLSLARALLRRSKILVLD 1399

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145  168 EPTTFLDPAHQLEILHLLKEinHIKQTTILMSIHDINHASRfSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:PLN03130  1400 EATAAVDVRTDALIQKTIRE--EFKSCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLLS 1461
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 7-232 3.05e-09

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 56.98  E-value: 3.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPkMLAQK--IAL 84
Cdd:PRK15439   12 LCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTP-AKAHQlgIYL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQsseHPL---GMTVEEVVSYG----RYPYQKFFSGLNEE----DLHAIQWALE-ATQltklkerelsslsggqaQRVW 152
Cdd:PRK15439   91 VPQ---EPLlfpNLSVKENILFGlpkrQASMQKMKQLLAALgcqlDLDSSAGSLEvADR-----------------QIVE 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 153 IAMALAQEADILILDEPTTFLDPAhqlEILHLLKEINHIKQTT--ILMSIHDINHASRFSDYLIGMKAGQIVVQG----- 225
Cdd:PRK15439  151 ILRGLMRDSRILILDEPTASLTPA---ETERLFSRIRELLAQGvgIVFISHKLPEIRQLADRISVMRDGTIALSGktadl 227


                  ....*..
gi 1560390145 226 TPDEVIT 232
Cdd:PRK15439  228 STDDIIQ 234
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
39-207 3.05e-09

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 55.58  E-value: 3.05e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  39 GPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKmLAQKIALLAqsseHPLG----MTVEEVVSYgrypYQKFFSG 114
Cdd:PRK13538   34 GPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDE-YHQDLLYLG----HQPGikteLTALENLRF----YQRLHGP 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 115 LNEEDLHAiqwALEATQLTKLKERELSSLSGGQAQRVwiamALA----QEADILILDEPTTFLDPAHQLEILHLLKEinH 190
Cdd:PRK13538  105 GDDEALWE---ALAQVGLAGFEDVPVRQLSAGQQRRV----ALArlwlTRAPLWILDEPFTAIDKQGVARLEALLAQ--H 175

                         170
                  ....*....|....*....
gi 1560390145 191 IKQ--TTILMSIHDINHAS 207
Cdd:PRK13538  176 AEQggMVILTTHQDLPVAS 194
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 21-181 3.69e-09

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 56.02  E-value: 3.69e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseistyspkmlaqKIALLAQSSEHPLGMTVEEV 100
Cdd:cd03291    52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSG-------------RISFSSQFSWIMPGTIKENI 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 ---VSYGRYPYQKFFSGLN-EEDLHAiqwaLEATQLTKLKERELSsLSGGQAQRVWIAMALAQEADILILDEPTTFLDPA 176
Cdd:cd03291   119 ifgVSYDEYRYKSVVKACQlEEDITK----FPEKDNTVLGEGGIT-LSGGQRARISLARAVYKDADLYLLDSPFGYLDVF 193


                  ....*
gi 1560390145 177 HQLEI 181
Cdd:cd03291   194 TEKEI 198
PLN03211 PLN03211
ABC transporter G-25; Provisional
 11-201 3.94e-09

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 56.81  E-value: 3.94e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  11 DITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK--EGKIIVDGSEIStyspKMLAQKIALLAQS 88
Cdd:PLN03211   73 DETRQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNnfTGTILANNRKPT----KQILKRTGFVTQD 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  89 SEHPLGMTVEEV---VSYGRYPYqkffSGLNEEDLHAIQWALEATQLTKLKERELSS-----LSGGQAQRVWIAMALAQE 160
Cdd:PLN03211  149 DILYPHLTVRETlvfCSLLRLPK----SLTKQEKILVAESVISELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLIN 224

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1560390145 161 ADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIH 201
Cdd:PLN03211  225 PSLLILDEPTSGLDATAAYRLVLTLGSLAQ-KGKTIVTSMH 264
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
14-231 4.36e-09

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 55.95  E-value: 4.36e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  14 TGYLNKQVIE---KMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSE 90
Cdd:PRK15112   18 TGWFRRQTVEavkPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSYRSQRIRMIFQDPS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  91 HPLGmtveevvsygryPYQKFFSGLN-----EEDLHAIqwALEATQLTKLKEREL---------SSLSGGQAQRVWIAMA 156
Cdd:PRK15112   98 TSLN------------PRQRISQILDfplrlNTDLEPE--QREKQIIETLRQVGLlpdhasyypHMLAPGQKQRLGLARA 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 157 LAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:PRK15112  164 LILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVL 238
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 32-205 6.09e-09

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 53.53  E-value: 6.09e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   32 GKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEIstyspkmlaqkiallaqssehplgmtveevvsygrypyqkf 111
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGED----------------------------------------- 40

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  112 fsglneedlhaIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEIL-----HLLK 186
Cdd:smart00382  41 -----------ILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLlleelRLLL 109

                          170
                   ....*....|....*....
gi 1560390145  187 EINHIKQTTILMSIHDINH 205
Cdd:smart00382 110 LLKSEKNLTVILTTNDEKD 128
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 21-254 9.21e-09

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 56.07  E-value: 9.21e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   21 VIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGseistyspkmlaqKIALLAQSSEHPLGMTVEEV 100
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSG-------------RISFSPQTSWIMPGTIKDNI 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  101 ---VSYGRYPYQKFFSGLN-EEDLhaiqwaleatqlTKLKERELS-------SLSGGQAQRVWIAMALAQEADILILDEP 169
Cdd:TIGR01271  508 ifgLSYDEYRYTSVIKACQlEEDI------------ALFPEKDKTvlgeggiTLSGGQRARISLARAVYKDADLYLLDSP 575

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  170 TTFLDPAHQLEILH--------------LLKEINHIKQTTILMSIHD------------INHASRFSDYLIGMKAGQIVV 223
Cdd:TIGR01271  576 FTHLDVVTEKEIFEsclcklmsnktrilVTSKLEHLKKADKILLLHEgvcyfygtfselQAKRPDFSSLLLGLEAFDNFS 655

                          250       260       270
                   ....*....|....*....|....*....|.
gi 1560390145  224 QGTPDEVITTSWMREIYEIEAQIIELPETNK 254
Cdd:TIGR01271  656 AERRNSILTETLRRVSIDGDSTVFSGPETIK 686
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 7-201 1.32e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 53.80  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEI----STYSpkmlaQKI 82
Cdd:PRK13540    2 LDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIkkdlCTYQ-----KQL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  83 ALLAQSSEHPLGMTVEEVVSYgrypyqkffsglneeDLHAIQWALEATQLTKLKERE------LSSLSGGQAQRVWIAMA 156
Cdd:PRK13540   77 CFVGHRSGINPYLTLRENCLY---------------DIHFSPGAVGITELCRLFSLEhlidypCGLLSSGQKRQVALLRL 141

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1560390145 157 LAQEADILILDEPTTFLDpahQLEILHLLKEIN-HIKQ-TTILMSIH 201
Cdd:PRK13540  142 WMSKAKLWLLDEPLVALD---ELSLLTIITKIQeHRAKgGAVLLTSH 185
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
6-199 1.44e-08

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 55.18  E-value: 1.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   6 TIEAVDITTGYLNKQViEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQK-IAL 84
Cdd:PRK09700  264 TVFEVRNVTSRDRKKV-RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDAVKKgMAY 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  85 LAQSSEH---------PLGMTVEEVVSYGRYpyqKFFSGLNEEDLHAiQWALEATQLTKLK----ERELSSLSGGQAQRV 151
Cdd:PRK09700  343 ITESRRDngffpnfsiAQNMAISRSLKDGGY---KGAMGLFHEVDEQ-RTAENQRELLALKchsvNQNITELSGGNQQKV 418

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1560390145 152 WIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMS 199
Cdd:PRK09700  419 LISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVS 466
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 18-174 1.98e-08

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 54.56  E-value: 1.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKsftrllpvkegkiIVDGSEiSTYSPKMLAQ---KIALLAQSSEHPLG 94
Cdd:TIGR03719  17 KKEILKDISLSFFPGAKIGVLGLNGAGKSTLLR-------------IMAGVD-KDFNGEARPQpgiKVGYLPQEPQLDPT 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 MTVEEVVSYGRYPYQKFFSGLNE---------EDLHA-------IQWALEATQLTKLkEREL----------------SS 142
Cdd:TIGR03719  83 KTVRENVEEGVAEIKDALDRFNEisakyaepdADFDKlaaeqaeLQEIIDAADAWDL-DSQLeiamdalrcppwdadvTK 161

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1560390145 143 LSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:TIGR03719 162 LSGGERRRVALCRLLLSKPDMLLLDEPTNHLD 193
PLN03140 PLN03140
ABC transporter G family member; Provisional
 29-232 2.89e-08

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 54.47  E-value: 2.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   29 IPEGKVTSLIGPNGSGKSTLLKSFT----RLLPVKeGKIIVDGSEISTYSPKMLAqkiALLAQSSEHPLGMTVEEVVSYG 104
Cdd:PLN03140   188 IKPSRMTLLLGPPSSGKTTLLLALAgkldPSLKVS-GEITYNGYRLNEFVPRKTS---AYISQNDVHVGVMTVKETLDFS 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  105 --------RYpyqKFFSGL------------NEEDLHAIQWALEATQL------------------TKLKERELSSLSGG 146
Cdd:PLN03140   264 arcqgvgtRY---DLLSELarrekdagifpeAEVDLFMKATAMEGVKSslitdytlkilgldickdTIVGDEMIRGISGG 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  147 QAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSIhdINHASR----FSDyLIGMKAGQIV 222
Cdd:PLN03140   341 QKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLMSL--LQPAPEtfdlFDD-IILLSEGQIV 417

                          250
                   ....*....|
gi 1560390145  223 VQGTPDEVIT 232
Cdd:PLN03140   418 YQGPRDHILE 427
ABC_Rad50 cd03240
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ...
 34-202 3.69e-08

ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.


Pssm-ID: 213207 [Multi-domain]  Cd Length: 204  Bit Score: 52.22  E-value: 3.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  34 VTSLIGPNGSGKSTLLK----SFTRLLPvkegkiivDGSEISTYSPKMlAQKIALLAQSSEHplgmtveevvsygrypyq 109
Cdd:cd03240    24 LTLIVGQNGAGKTTIIEalkyALTGELP--------PNSKGGAHDPKL-IREGEVRAQVKLA------------------ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 110 kfFSGLNEEDLHAIQW--ALEAT------QLTKLKERELSSLSGGQ------AQRVWIAMALAQEADILILDEPTTFLDP 175
Cdd:cd03240    77 --FENANGKKYTITRSlaILENVifchqgESNWPLLDMRGRCSGGEkvlaslIIRLALAETFGSNCGILALDEPTTNLDE 154

                         170       180
                  ....*....|....*....|....*...
gi 1560390145 176 AHQLEILH-LLKEINHIKQTTILMSIHD 202
Cdd:cd03240   155 ENIEESLAeIIEERKSQKNFQLIVITHD 182
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 26-211 5.22e-08

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 53.48  E-value: 5.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSSEHPL--------GMTV 97
Cdd:PRK10938   23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMlspgeddtGRTT 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  98 EEVVsygrypyqkffsglnEEDLHAIQWALE-ATQL--TKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:PRK10938  103 AEII---------------QDEVKDPARCEQlAQQFgiTALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLD 167

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1560390145 175 PAHQLEILHLLKEINHIKQTTILMSihdinhaSRFSD 211
Cdd:PRK10938  168 VASRQQLAELLASLHQSGITLVLVL-------NRFDE 197
GguA NF040905
sugar ABC transporter ATP-binding protein;
26-211 8.47e-08

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.87  E-value: 8.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP--VKEGKIIVDGSEISTYSPK--------MLAQKIALLaqssehPLgM 95
Cdd:NF040905   21 NLSVREGEIHALCGENGAGKSTLMKVLSGVYPhgSYEGEILFDGEVCRFKDIRdsealgivIIHQELALI------PY-L 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  96 TVEEVVsygrypyqkfFSGlNEedlHA----IQWA---LEATQLTK---LKER---ELSSLSGGQAQRVWIAMALAQEAD 162
Cdd:NF040905   94 SIAENI----------FLG-NE---RAkrgvIDWNetnRRARELLAkvgLDESpdtLVTDIGVGKQQLVEIAKALSKDVK 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1560390145 163 ILILDEPTTFL---DPAHQLEILHLLKEinhikQ--TTILMSiHDINHASRFSD 211
Cdd:NF040905  160 LLILDEPTAALneeDSAALLDLLLELKA-----QgiTSIIIS-HKLNEIRRVAD 207
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 94-231 1.02e-07

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 52.91  E-value: 1.02e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   94 GMTVEEVVSYGRYPYQKFFsgLNEEDLHAIQWALEATQLTKLK-ERELSSLSGGQAQRVWIAMAL---AQEADILILDEP 169
Cdd:PRK00635   762 GKNIADILEMTAYEAEKFF--LDEPSIHEKIHALCSLGLDYLPlGRPLSSLSGGEIQRLKLAYELlapSKKPTLYVLDEP 839

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145  170 TTFLDPAHQLEILHLLKEINHIKQTTILMSiHDInHASRFSDYLI------GMKAGQIVVQGTPDEVI 231
Cdd:PRK00635   840 TTGLHTHDIKALIYVLQSLTHQGHTVVIIE-HNM-HVVKVADYVLelgpegGNLGGYLLASCSPEELI 905
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
 19-231 1.74e-07

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 51.06  E-value: 1.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLAQSsehPLgmtve 98
Cdd:cd03288    34 KPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQD---PI----- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  99 evvsygrypyqkFFSG-----LNEEDLHAIQWALEATQLTKLKEReLSSLSG---------------GQAQRVWIAMALA 158
Cdd:cd03288   106 ------------LFSGsirfnLDPECKCTDDRLWEALEIAQLKNM-VKSLPGgldavvteggenfsvGQRQLFCLARAFV 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1560390145 159 QEADILILDEPTTFLDPAHQlEILHLLKEINHIKQTTILMS--IHDINHAsrfsDYLIGMKAGQIVVQGTPDEVI 231
Cdd:cd03288   173 RKSSILIMDEATASIDMATE-NILQKVVMTAFADRTVVTIAhrVSTILDA----DLVLVLSRGILVECDTPENLL 242
PLN03130 PLN03130
ABC transporter C family member; Provisional
 9-257 2.13e-07

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 51.66  E-value: 2.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145    9 AVDITTGYL------NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKS-FTRLLPVKEGKIIVDGSeistyspkmlaqk 81
Cdd:PLN03130   614 AISIKNGYFswdskaERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAmLGELPPRSDASVVIRGT------------- 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   82 IALLAQSSeHPLGMTVEEVVSYGRyPYQ--KFFSGLNEEDLHAIQWALEATQLTKLKERELSsLSGGQAQRVWIAMALAQ 159
Cdd:PLN03130   681 VAYVPQVS-WIFNATVRDNILFGS-PFDpeRYERAIDVTALQHDLDLLPGGDLTEIGERGVN-ISGGQKQRVSMARAVYS 757

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  160 EADILILDEPTTFLDpAH---QLEILHLLKEINHIKQTTILMSIHDINHAsrfsDYLIGMKAGQIVVQGTPDEVITTSW- 235
Cdd:PLN03130   758 NSDVYIFDDPLSALD-AHvgrQVFDKCIKDELRGKTRVLVTNQLHFLSQV----DRIILVHEGMIKEEGTYEELSNNGPl 832

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1560390145  236 ----------MREIYEIEAQIIELPETNKPVV 257
Cdd:PLN03130   833 fqklmenagkMEEYVEENGEEEDDQTSSKPVA 864
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 7-229 3.60e-07

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 50.66  E-value: 3.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKiiVDGSEIStyspkmlaqKIALLA 86
Cdd:PRK15064  320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGT--VKWSENA---------NIGYYA 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEH--PLGMTVEEVVSYGRYPyqkffsGLNEEDLHAIQWALEATQLTKLKerELSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:PRK15064  389 QDHAYdfENDLTLFDWMSQWRQE------GDDEQAVRGTLGRLLFSQDDIKK--SVKVLSGGEKGRMLFGKLMMQKPNVL 460

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1560390145 165 ILDEPTTFLDpAHQLEILHLLKEinHIKQTTILMSiHDINHASRFSDYLIGMKAGQIV-VQGTPDE 229
Cdd:PRK15064  461 VMDEPTNHMD-MESIESLNMALE--KYEGTLIFVS-HDREFVSSLATRIIEITPDGVVdFSGTYEE 522
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 8-202 6.70e-07

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 49.95  E-value: 6.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   8 EAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVdGSEIstyspkmlaqKIALLAQ 87
Cdd:PRK11147  321 EMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHC-GTKL----------EVAYFDQ 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 SSEH--PlGMTVEEVVSYGRypyQKFFsgLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILI 165
Cdd:PRK11147  390 HRAEldP-EKTVMDNLAEGK---QEVM--VNGRPRHVLGYLQDFLFHPKRAMTPVKALSGGERNRLLLARLFLKPSNLLI 463

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1560390145 166 LDEPTTFLDpahqLEILHLLKEINHIKQTTILMSIHD 202
Cdd:PRK11147  464 LDEPTNDLD----VETLELLEELLDSYQGTVLLVSHD 496
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 26-217 1.31e-06

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 47.35  E-value: 1.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSftrllpvkegkIIVdgseistyspkmlaqkIALLAQSSEHPLGMTVEEVVSygr 105
Cdd:cd03227    15 DVTFGEGSLTIITGPNGSGKSTILDA-----------IGL----------------ALGGAQSATRRRSGVKAGCIV--- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 106 yPYQKffsglneedLHAIQwaleatqltklkerELSSLSGGQAQRVWIAMALA----QEADILILDEPTTFLDPAHQLEI 181
Cdd:cd03227    65 -AAVS---------AELIF--------------TRLQLSGGEKELSALALILAlaslKPRPLYILDEIDRGLDPRDGQAL 120

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1560390145 182 LHLLKEinHIKQTTILMSIHDINHASRFSDYLIGMK 217
Cdd:cd03227   121 AEAILE--HLVKGAQVIVITHLPELAELADKLIHIK 154
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
127-249 1.36e-06

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 48.96  E-value: 1.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 127 LEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIHDINHA 206
Cdd:NF000106  129 LERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVR-DGATVLLTTQYMEEA 207

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1560390145 207 SRFSDYLIGMKAGQIVVQGTPDEVITTSWMREIYEIEAQIIEL 249
Cdd:NF000106  208 EQLAHELTVIDRGRVIADGKVDELKTKVGGRTLQIRPAHAAEL 250
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 42-170 1.37e-06

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 48.87  E-value: 1.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  42 GSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSP-KMLAQKIALLaqsSEHPLG------MTVEE---VVSYGRYPYQKF 111
Cdd:COG3845   294 GNGQSELAEALAGLRPPASGSIRLDGEDITGLSPrERRRLGVAYI---PEDRLGrglvpdMSVAEnliLGRYRRPPFSRG 370

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1560390145 112 FSglneedlhaIQWALEATQLTKLKER----------ELSSLSGGQAQRVWIAMALAQEADILILDEPT 170
Cdd:COG3845   371 GF---------LDRKAIRAFAEELIEEfdvrtpgpdtPARSLSGGNQQKVILARELSRDPKLLIAAQPT 430
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
137-231 1.62e-06

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 48.87  E-value: 1.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 137 ERELSSLSGGQAQRVWIAMAL-AQEADIL-ILDEPTTFLdpaHQ------LEILHLLKEI-NhikqtTILMSIHD---IN 204
Cdd:COG0178   480 DRSAGTLSGGEAQRIRLATQIgSGLVGVLyVLDEPSIGL---HQrdndrlIETLKRLRDLgN-----TVIVVEHDedtIR 551

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1560390145 205 HAsrfsDYLI------GMKAGQIVVQGTPDEVI 231
Cdd:COG0178   552 AA----DYIIdigpgaGEHGGEVVAQGTPEEIL 580
PLN03073 PLN03073
ABC transporter F family; Provisional
 36-202 2.16e-06

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 48.70  E-value: 2.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  36 SLIGPNGSGKSTLLKSFTRLLPVKEGKIIvdgseistYSPKMlaqKIALLAQSSEHPLGMTVEEVVSYGRypyqkFFSGL 115
Cdd:PLN03073  539 AMVGPNGIGKSTILKLISGELQPSSGTVF--------RSAKV---RMAVFSQHHVDGLDLSSNPLLYMMR-----CFPGV 602

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 116 NEEDLHAIQWALEATqlTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDpahqLEILHLLKEINHIKQTT 195
Cdd:PLN03073  603 PEQKLRAHLGSFGVT--GNLALQPMYTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD----LDAVEALIQGLVLFQGG 676


                  ....*..
gi 1560390145 196 ILMSIHD 202
Cdd:PLN03073  677 VLMVSHD 683
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 137-230 2.58e-06

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 48.47  E-value: 2.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 137 ERELSSLSGGQAQRVWIAMALAQE--ADILILDEPTTFLdpaHQLEILHLLKEINHIKQ--TTILMSIHD---INHASRF 209
Cdd:TIGR00630 483 SRAAGTLSGGEAQRIRLATQIGSGltGVLYVLDEPSIGL---HQRDNRRLINTLKRLRDlgNTLIVVEHDedtIRAADYV 559

                          90       100
                  ....*....|....*....|....*
gi 1560390145 210 SDylIGMKA----GQIVVQGTPDEV 230
Cdd:TIGR00630 560 ID--IGPGAgehgGEVVASGTPEEI 582
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 22-185 2.86e-06

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 47.90  E-value: 2.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVK-EGKIIVDGSEISTYSPkmlaqkiallAQSSEHPLGMTVEEV 100
Cdd:TIGR02633 276 VDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVDIRNP----------AQAIRAGIAMVPEDR 345

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 101 VSYGRYPYQ-----------KFFSGLNEEDLHAIQWAL-EATQLTKLKERE----LSSLSGGQAQRVWIAMALAQEADIL 164
Cdd:TIGR02633 346 KRHGIVPILgvgknitlsvlKSFCFKMRIDAAAELQIIgSAIQRLKVKTASpflpIGRLSGGNQQKAVLAKMLLTNPRVL 425

                         170       180
                  ....*....|....*....|.
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLL 185
Cdd:TIGR02633 426 ILDEPTRGVDVGAKYEIYKLI 446
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 18-185 4.30e-06

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 47.62  E-value: 4.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  18 NKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLP-VKEGKIIVDGSEISTYSP-KMLAQKIALLAQSSEH---- 91
Cdd:PRK13549  274 HIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPgRWEGEIFIDGKPVKIRNPqQAIAQGIAMVPEDRKRdgiv 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  92 PLgMTVEE---VVSYGRYpyqKFFSGLNEE-DLHAIQwalEATQLTKLK----ERELSSLSGGQAQRVWIAMALAQEADI 163
Cdd:PRK13549  354 PV-MGVGKnitLAALDRF---TGGSRIDDAaELKTIL---ESIQRLKVKtaspELAIARLSGGNQQKAVLAKCLLLNPKI 426

                         170       180
                  ....*....|....*....|..
gi 1560390145 164 LILDEPTTFLDPAHQLEILHLL 185
Cdd:PRK13549  427 LILDEPTRGIDVGAKYEIYKLI 448
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 17-199 5.66e-06

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 47.03  E-value: 5.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  17 LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKmlaqkiallaQSSEHPLGMT 96
Cdd:PRK10982  259 LRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNAN----------EAINHGFALV 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  97 VEEVVSYGRYP---------------YQKFFSGLNEEDLHA-IQWALEATQL-TKLKERELSSLSGGQAQRVWIAMALAQ 159
Cdd:PRK10982  329 TEERRSTGIYAyldigfnslisnirnYKNKVGLLDNSRMKSdTQWVIDSMRVkTPGHRTQIGSLSGGNQQKVIIGRWLLT 408

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1560390145 160 EADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMS 199
Cdd:PRK10982  409 QPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIIS 448
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 32-201 6.55e-06

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 47.41  E-value: 6.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   32 GKVTSLIGPNGSGKSTLLKSftrLLPVKEGKIIVDGSEISTYSP--KMLAQKIALLAQSSEHPLGMTVEEVVSYGRYPYQ 109
Cdd:TIGR00956  789 GTLTALMGASGAGKTTLLNV---LAERVTTGVITGGDRLVNGRPldSSFQRSIGYVQQQDLHLPTSTVRESLRFSAYLRQ 865

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  110 KFFSGLNEEDLHaIQWALEATQLTKLKEREL----SSLSGGQAQRVWIAMALAQEADILI-LDEPTTFLDPAHQLEILHL 184
Cdd:TIGR00956  866 PKSVSKSEKMEY-VEEVIKLLEMESYADAVVgvpgEGLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLDSQTAWSICKL 944

                          170
                   ....*....|....*..
gi 1560390145  185 LKEINHIKQtTILMSIH 201
Cdd:TIGR00956  945 MRKLADHGQ-AILCTIH 960
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 29-202 6.78e-06

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 47.09  E-value: 6.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  29 IPEGKVTSLIGPNGSGKSTLLKsftrLLpvkEGKIIVDGSEIStyspkmLAQKIALLAQSSEHP-LGMTVEEVVSYGRYP 107
Cdd:PRK10636   24 INPGQKVGLVGKNGCGKSTLLA----LL---KNEISADGGSYT------FPGNWQLAWVNQETPaLPQPALEYVIDGDRE 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 108 YQKFFSGLN----EEDLHAIQ-----------WALEATQLTKLK---------ERELSSLSGGQAQRVWIAMALAQEADI 163
Cdd:PRK10636   91 YRQLEAQLHdaneRNDGHAIAtihgkldaidaWTIRSRAASLLHglgfsneqlERPVSDFSGGWRMRLNLAQALICRSDL 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1560390145 164 LILDEPTTFLDpahqLE-ILHLLKEINHIKQTTILMSiHD 202
Cdd:PRK10636  171 LLLDEPTNHLD----LDaVIWLEKWLKSYQGTLILIS-HD 205
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 37-174 6.88e-06

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 47.04  E-value: 6.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  37 LIGPNGSGKSTLLKSFTRLLPVKEGKIIVdgseistySPKMlaqKIALLAQssEHPL--GMTVEEVVSYG---------R 105
Cdd:PRK11819   38 VLGLNGAGKSTLLRIMAGVDKEFEGEARP--------APGI---KVGYLPQ--EPQLdpEKTVRENVEEGvaevkaaldR 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 106 YP--YQKF------FSGLNEE--DLHAIQWALEATQL-TKL-----------KERELSSLSGGQAQRVWIAMALAQEADI 163
Cdd:PRK11819  105 FNeiYAAYaepdadFDALAAEqgELQEIIDAADAWDLdSQLeiamdalrcppWDAKVTKLSGGERRRVALCRLLLEKPDM 184

                         170
                  ....*....|.
gi 1560390145 164 LILDEPTTFLD 174
Cdd:PRK11819  185 LLLDEPTNHLD 195
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 19-174 7.75e-06

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 45.94  E-value: 7.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  19 KQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFT--RLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA---------Q 87
Cdd:PRK09580   14 KAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAgrEDYEVTGGTVEFKGKDLLELSPEDRAGEGIFMAfqypveipgV 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  88 SSEHPLGMTVEEVVSY-GRYPYQKF-FSGLNEEDLHAIQwaLEATQLTklkeRELS-SLSGGQAQRVWIAMALAQEADIL 164
Cdd:PRK09580   94 SNQFFLQTALNAVRSYrGQEPLDRFdFQDLMEEKIALLK--MPEDLLT----RSVNvGFSGGEKKRNDILQMAVLEPELC 167

                         170
                  ....*....|
gi 1560390145 165 ILDEPTTFLD 174
Cdd:PRK09580  168 ILDESDSGLD 177
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 111-251 1.05e-05

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 46.75  E-value: 1.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  111 FFSGLNEEDLhAIQWALEA--TQLTKL---------KERELSSLSGGQAQRVWIAMALAQE--ADILILDEPTTFLDPAH 177
Cdd:PRK00635   435 FLSQLPSKSL-SIEEVLQGlkSRLSILidlglpyltPERALATLSGGEQERTALAKHLGAEliGITYILDEPSIGLHPQD 513

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  178 QLEILHLLKEINHiKQTTILMSIHD---INHASRFSDylIGMKA----GQIVVQGTPDEVITTS-WMREIYEIEAQIIEL 249
Cdd:PRK00635   514 THKLINVIKKLRD-QGNTVLLVEHDeqmISLADRIID--IGPGAgifgGEVLFNGSPREFLAKSdSLTAKYLRQELTIPI 590


                   ..
gi 1560390145  250 PE 251
Cdd:PRK00635   591 PE 592
PLN03140 PLN03140
ABC transporter G family member; Provisional
 32-246 1.19e-05

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 46.38  E-value: 1.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   32 GKVTSLIGPNGSGKSTLLKSftrLLPVKEGKIIVDGSEISTYSPKM--LAQKIALLAQSSEHPLGMTVEEVVSYG---RY 106
Cdd:PLN03140   906 GVLTALMGVSGAGKTTLMDV---LAGRKTGGYIEGDIRISGFPKKQetFARISGYCEQNDIHSPQVTVRESLIYSaflRL 982

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  107 PyqKFFSglNEEDLHAIQWALEATQLTKLKER-----ELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDpAHQLEI 181
Cdd:PLN03140   983 P--KEVS--KEEKMMFVDEVMELVELDNLKDAivglpGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLD-ARAAAI 1057

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  182 lhLLKEINHIKQT--TILMSIH----DINHAsrFSDYLIGMKAGQIVVQGT---------------------PDEVITTS 234
Cdd:PLN03140  1058 --VMRTVRNTVDTgrTVVCTIHqpsiDIFEA--FDELLLMKRGGQVIYSGPlgrnshkiieyfeaipgvpkiKEKYNPAT 1133

                          250
                   ....*....|..
gi 1560390145  235 WMREIYEIEAQI 246
Cdd:PLN03140  1134 WMLEVSSLAAEV 1145
AAA_29 pfam13555
P-loop containing region of AAA domain;
15-56 1.90e-05

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 41.43  E-value: 1.90e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1560390145  15 GYLNKQVIEkmsikIPEGKVTSLIGPNGSGKSTLLKSFTRLL 56
Cdd:pfam13555  10 GTFDGHTIP-----IDPRGNTLLTGPSGSGKSTLLDAIQTLL 46
COG4938 COG4938
Predicted ATPase [General function prediction only];
22-230 2.86e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443965 [Multi-domain]  Cd Length: 277  Bit Score: 44.57  E-value: 2.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIpeGKVTSLIGPNGSGKSTLLKSFT-------------RLLPVKEGKIIVDGSEISTYSPKMLAQkiaLLAQS 88
Cdd:COG4938    12 FKEAELEL--KPLTLLIGPNGSGKSTLIQALLlllqsnfiylpaeRSGPARLYPSLVRELSDLGSRGEYTAD---FLAEL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  89 SEHPLGMTVEEVVSYGRYPY-QKFFSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMAL---AQEADIL 164
Cdd:COG4938    87 ENLEILDDKSKELLEQVEEWlEKIFPGKVEVDASSDLVRLVFRPSGNGKRIPLSNVGSGVSELLPILLALlsaAKPGSLL 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 165 ILDEPTTFLDPAHQLEILHLLKEI-NHIKQttILMSIHdinhasrfSDYLI-----GMKAGQIVvqgTPDEV 230
Cdd:COG4938   167 IIEEPEAHLHPKAQSALAELLAELaNSGVQ--VIIETH--------SDYILnglrnLIKEGKLL---DPDDV 225
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 25-232 4.34e-05

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 44.50  E-value: 4.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  25 MSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEistyspkmlaqkiALLAQSSEHPLGMTVEEVVSyg 104
Cdd:PRK13545   43 ISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSA-------------ALIAISSGLNGQLTGIENIE-- 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 105 rypYQKFFSGLNEEDLHAI-QWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDpahQLEILH 183
Cdd:PRK13545  108 ---LKGLMMGLTKEKIKEIiPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGD---QTFTKK 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 184 LLKEINHIKQT--TILMSIHDINHASRFSDYLIGMKAGQIVVQGTPDEVIT 232
Cdd:PRK13545  182 CLDKMNEFKEQgkTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIKEVVD 232
PLN03073 PLN03073
ABC transporter F family; Provisional
 7-174 5.52e-05

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 44.08  E-value: 5.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGylNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFT-----------RLLPVKEGkiiVDGSEISTYS- 74
Cdd:PLN03073  180 MENFSISVG--GRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMAmhaidgipkncQILHVEQE---VVGDDTTALQc 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  75 --------PKMLAQKIALLAQ--------------------SSEHPLGMTVEEVvsYGRYPYQKFFSGlnEEDLHAIQWA 126
Cdd:PLN03073  255 vlntdierTQLLEEEAQLVAQqrelefetetgkgkgankdgVDKDAVSQRLEEI--YKRLELIDAYTA--EARAASILAG 330

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1560390145 127 LEATqlTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:PLN03073  331 LSFT--PEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLD 376
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 34-227 9.01e-05

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 43.15  E-value: 9.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  34 VTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYSPKMLAQKIALLA--QSSEHPLGMTVEEVVSYgrypyqKF 111
Cdd:pfam13304   1 INVLIGPNGSGKSNLLEALRFLADFDALVIGLTDERSRNGGIGGIPSLLNGIDpkEPIEFEISEFLEDGVRY------RY 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 112 FSGLNEEDLHAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHI 191
Cdd:pfam13304  75 GLDLEREDVEEKLSSKPTLLEKRLLLREDSEEREPKFPPEAEELRLGLDVEERIELSLSELSDLISGLLLLSIISPLSFL 154

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1560390145 192 KQTTILMSIHDINHASRFSDYLIGMKAGQIVVQGTP 227
Cdd:pfam13304 155 LLLDEGLLLEDWAVLDLAADLALFPDLKELLQRLVR 190
ABC_sbcCD cd03279
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ...
 14-189 1.17e-04

ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.


Pssm-ID: 213246 [Multi-domain]  Cd Length: 213  Bit Score: 42.26  E-value: 1.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  14 TGYLNKQVIEKMSIkipEGKVTSLI-GPNGSGKSTLLKSFTRLLpvkEGKIIVDGSEISTYSpkmlaqkialLAQSSEHP 92
Cdd:cd03279    12 GPFREEQVIDFTGL---DNNGLFLIcGPTGAGKSTILDAITYAL---YGKTPRYGRQENLRS----------VFAPGEDT 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  93 LGMTVEEVVSYGRYPYQKFFsGLNEEDLhaIQWA-LEATQLTKLKERELSSLSGGQAQRVWIAMALA-----QEA----- 161
Cdd:cd03279    76 AEVSFTFQLGGKKYRVERSR-GLDYDQF--TRIVlLPQGEFDRFLARPVSTLSGGETFLASLSLALAlsevlQNRggarl 152

                         170       180
                  ....*....|....*....|....*...
gi 1560390145 162 DILILDEPTTFLDPAHQLEILHLLKEIN 189
Cdd:cd03279   153 EALFIDEGFGTLDPEALEAVATALELIR 180
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
34-191 1.35e-04

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 41.92  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  34 VTSLIGPNGSGKSTLLKSFTRLLpvkEGKIIVDGSEIStyspkmlaqkiALLAQSSEHplgMTVEEVVSYGRYPY----- 108
Cdd:COG0419    25 LNLIVGPNGAGKSTILEAIRYAL---YGKARSRSKLRS-----------DLINVGSEE---ASVELEFEHGGKRYrierr 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 109 ---------------QKFFSGL--------NEEDLHAIQWALE-----ATQLTKLKERELS---------SLSGGQAqrv 151
Cdd:COG0419    88 qgefaefleakpserKEALKRLlgleiyeeLKERLKELEEALEsaleeLAELQKLKQEILAqlsgldpieTLSGGER--- 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1560390145 152 wIAMALAQEADiLILDepTTFLDPAHQLEILHLLKEINHI 191
Cdd:COG0419   165 -LRLALADLLS-LILD--FGSLDEERLERLLDALEELAII 200
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
136-174 1.50e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 1.50e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1560390145 136 KERELSSLSGGQ------AQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:PRK03918  782 KERPLTFLSGGErialglAFRLALSLYLAGNIPLLILDEPTPFLD 826
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
 22-201 1.67e-04

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 42.30  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGkVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIV--DGSEISTYSP---------KMLAQKI--ALLAQS 88
Cdd:COG3593    14 IKDLSIELSDD-LTVLVGENNSGKSSILEALRLLLGPSSSRKFDeeDFYLGDDPDLpeieieltfGSLLSRLlrLLLKEE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  89 SEHPLGMTVEEVvsygRYPYQKFFSGLNEE---------DLHAIQWALEATQLTKL-----------KERELSSLSGGQA 148
Cdd:COG3593    93 DKEELEEALEEL----NEELKEALKALNELlseylkellDGLDLELELSLDELEDLlkslslriedgKELPLDRLGSGFQ 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560390145 149 QrvWIAMALAQ---------EADILILDEPTTFLDPAHQLEILHLLKEINHiKQTTILMSIH 201
Cdd:COG3593   169 R--LILLALLSalaelkrapANPILLIEEPEAHLHPQAQRRLLKLLKELSE-KPNQVIITTH 227
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 17-174 1.98e-04

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 41.40  E-value: 1.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  17 LNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEISTYsPKMLAQKIAllaqsseHPLGMT 96
Cdd:PRK13541   11 IEQKNLFDLSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNI-AKPYCTYIG-------HNLGLK 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1560390145  97 VEEVVSYGRYPYQKFFSGLNeedlhAIQWALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLD 174
Cdd:PRK13541   83 LEMTVFENLKFWSEIYNSAE-----TLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLS 155
uvrA PRK00349
excinuclease ABC subunit UvrA;
137-231 2.17e-04

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 42.37  E-value: 2.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 137 ERELSSLSGGQAQRVWIAmalAQeadI---L-----ILDEPTTFLdpaHQ------LEILHLLKEI-NhikqtTILMSIH 201
Cdd:PRK00349  484 SRSAGTLSGGEAQRIRLA---TQ---IgsgLtgvlyVLDEPSIGL---HQrdndrlIETLKHLRDLgN-----TLIVVEH 549

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1560390145 202 D---INHAsrfsDYL--IGMKAG----QIVVQGTPDEVI 231
Cdd:PRK00349  550 DedtIRAA----DYIvdIGPGAGvhggEVVASGTPEEIM 584
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
143-232 2.27e-04

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 42.21  E-value: 2.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 143 LSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLEILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIV 222
Cdd:PRK11288  397 LSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVS-SDLPEVLGVADRIVVMREGRIA 475

                          90
                  ....*....|....*
gi 1560390145 223 -----VQGTPDEVIT 232
Cdd:PRK11288  476 gelarEQATERQALS 490
COG4637 COG4637
Predicted ATPase [General function prediction only];
4-56 3.34e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443675 [Multi-domain]  Cd Length: 371  Bit Score: 41.45  E-value: 3.34e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1560390145   4 LTTIEAvditTGYLNkqvIEKMSIKIpeGKVTSLIGPNGSGKSTLLKSFtRLL 56
Cdd:COG4637     2 ITRIRI----KNFKS---LRDLELPL--GPLTVLIGANGSGKSNLLDAL-RFL 44
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 7-175 4.34e-04

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 41.15  E-value: 4.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKsftrllpvkegkiIVDGSEISTYSPKM--------- 77
Cdd:PRK10938  261 IVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLS-------------LITGDHPQGYSNDLtlfgrrrgs 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  78 ------LAQKIALLAQS--SEHPLGMTVEEVVSYGrypyqkFFS--GL-----NEEDLHAIQWaLEATQLTK-LKERELS 141
Cdd:PRK10938  328 getiwdIKKHIGYVSSSlhLDYRVSTSVRNVILSG------FFDsiGIyqavsDRQQKLAQQW-LDILGIDKrTADAPFH 400

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1560390145 142 SLSGGQAQRVWIAMALAQEADILILDEPTTFLDP 175
Cdd:PRK10938  401 SLSWGQQRLALIVRALVKHPTLLILDEPLQGLDP 434
COG3950 COG3950
Predicted ATP-binding protein involved in virulence [General function prediction only];
22-201 5.02e-04

Predicted ATP-binding protein involved in virulence [General function prediction only];


Pssm-ID: 443150 [Multi-domain]  Cd Length: 276  Bit Score: 40.75  E-value: 5.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEG-KVTSLIGPNGSGKSTLLKSFTRLLPVKEGKII-VDGSEISTYSPKMLAQKIALLAQSS-----EHPLG 94
Cdd:COG3950    14 FEDLEIDFDNPpRLTVLVGENGSGKTTLLEAIALALSGLLSRLDdVKFRKLLIRNGEFGDSAKLILYYGTsrlllDGPLK 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  95 MTVEEVVSYG------------RYPYQKFFSGLNE--EDLHAIQWALEATQLTKLK------------------------ 136
Cdd:COG3950    94 KLERLKEEYFsrldgydslldeDSNLREFLEWLREylEDLENKLSDELDEKLEAVRealnkllpdfkdiridrdpgrlvi 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 137 ------ERELSSLSGGQAQRV----WIAMALAQEAD----------ILILDEPTTFLDPAHQLEILHLLKEInhIKQTTI 196
Cdd:COG3950   174 ldkngeELPLNQLSDGERSLLalvgDLARRLAELNPalenplegegIVLIDEIDLHLHPKWQRRILPDLRKI--FPNIQF 251


                  ....*
gi 1560390145 197 LMSIH 201
Cdd:COG3950   252 IVTTH 256
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 7-202 1.49e-03

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 39.49  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145   7 IEAVDITTGYLNKQVIEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGSEistyspkmlaqKIALLA 86
Cdd:PRK15064    2 LSTANITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNE-----------RLGKLR 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  87 QSSEHPLGMTVEEVVSYGrypYQKFFSGLNEEDlhAIQWALEATQLTKLKEREL-------------------------- 140
Cdd:PRK15064   71 QDQFAFEEFTVLDTVIMG---HTELWEVKQERD--RIYALPEMSEEDGMKVADLevkfaemdgytaearagelllgvgip 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 141 --------SSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAhqlEILHLLKEINHIKQTTILMSiHD 202
Cdd:PRK15064  146 eeqhyglmSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDIN---TIRWLEDVLNERNSTMIIIS-HD 211
ABC_SMC_barmotin cd03278
ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a ...
 23-46 4.00e-03

ATP-binding cassette domain of barmotin, a member of the SMC protein family; Barmotin is a tight junction-associated protein expressed in rat epithelial cells which is thought to have an important regulatory role in tight junction barrier function. Barmotin belongs to the SMC protein family. SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).


Pssm-ID: 213245 [Multi-domain]  Cd Length: 197  Bit Score: 37.44  E-value: 4.00e-03
                          10        20
                  ....*....|....*....|....
gi 1560390145  23 EKMSIKIPEGkVTSLIGPNGSGKS 46
Cdd:cd03278    14 DKTTIPFPPG-LTAIVGPNGSGKS 36
PulE-GspE-like cd01129
PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II ...
 20-64 4.70e-03

PulE-GspE family; PulE and General secretory pathway protein GspE are ATPases of the type II secretory pathway, the main terminal branch of the general secretory pathway (GSP). PulE is a cytoplasmic protein of the GSP, which contains an ATP binding site and a tetracysteine motif. This subgroup also includes PilB, a type IV pilus assembly ATPase, DotB, an ATPase of the type IVb secretion system, also known as the dot/icm system, Escherichia coli IncI plasmid-encoded conjugative transfer ATPase TraJ, and HofB.


Pssm-ID: 410873 [Multi-domain]  Cd Length: 159  Bit Score: 36.69  E-value: 4.70e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1560390145  20 QVIEKMsIKIPEGKVtsLI-GPNGSGKSTLLKSFTRLLPVKEGKII 64
Cdd:cd01129     1 ARLRRL-IKRPHGLI--LVtGPTGSGKTTTLYAMLRELNGPERNII 43
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
22-231 5.59e-03

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 37.49  E-value: 5.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145  22 IEKMSIKIPEGKVTSLIGPNGSGKSTLLKSFTRLLPVKEGKIIVDGsEISTyspkmlaqkIALLAQSSEHPLGMTVEEvv 101
Cdd:PRK13546   40 LDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG-EVSV---------IAISAGLSGQLTGIENIE-- 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560390145 102 sygrypYQKFFSGLNEEDLHAIQ-WALEATQLTKLKERELSSLSGGQAQRVWIAMALAQEADILILDEPTTFLDPAHQLE 180
Cdd:PRK13546  108 ------FKMLCMGFKRKEIKAMTpKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQK 181

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1560390145 181 ILHLLKEINHIKQTTILMSiHDINHASRFSDYLIGMKAGQIVVQGTPDEVI 231
Cdd:PRK13546  182 CLDKIYEFKEQNKTIFFVS-HNLGQVRQFCTKIAWIEGGKLKDYGELDDVL 231
ABC_MutS_homologs cd03243
ATP-binding cassette domain of MutS homologs; The MutS protein initiates DNA mismatch repair ...
 26-52 7.56e-03

ATP-binding cassette domain of MutS homologs; The MutS protein initiates DNA mismatch repair by recognizing mispaired and unpaired bases embedded in duplex DNA and activating endo- and exonucleases to remove the mismatch. Members of the MutS family also possess a conserved ATPase activity that belongs to the ATP binding cassette (ABC) superfamily. MutS homologs (MSH) have been identified in most prokaryotic and all eukaryotic organisms examined. Prokaryotes have two homologs (MutS1 and MutS2), whereas seven MSH proteins (MSH1 to MSH7) have been identified in eukaryotes. The homodimer MutS1 and heterodimers MSH2-MSH3 and MSH2-MSH6 are primarily involved in mitotic mismatch repair, whereas MSH4-MSH5 is involved in resolution of Holliday junctions during meiosis. All members of the MutS family contain the highly conserved Walker A/B ATPase domain, and many share a common mechanism of action. MutS1, MSH2-MSH3, MSH2-MSH6, and MSH4-MSH5 dimerize to form sliding clamps, and recognition of specific DNA structures or lesions results in ADP/ATP exchange.


Pssm-ID: 213210 [Multi-domain]  Cd Length: 202  Bit Score: 36.84  E-value: 7.56e-03
                          10        20
                  ....*....|....*....|....*..
gi 1560390145  26 SIKIPEGKVTSLIGPNGSGKSTLLKSF 52
Cdd:cd03243    23 DINLGSGRLLLITGPNMGGKSTYLRSI 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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