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Conserved domains on  [gi|1570010338|gb|RYP11495|]
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hypothetical protein DL764_000018 [Monosporascus ibericus]

Protein Classification

RCC1-like domain-containing protein( domain architecture ID 20422823)

RCC1 (regulator of chromosome condensation)-like (RLD) domain-containing protein harbors a versatile domain which may perform many different functions, including guanine nucleotide exchange on small GTP-binding proteins, enzyme inhibition or interaction with proteins and lipids

Gene Ontology:  GO:0005085|GO:0007165
PubMed:  18442486

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 164-560 1.95e-54

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 187.49  E-value: 1.95e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 164 VQVACGGMHVGALTKDNKIYTWGVNDDRALGRDTTWDgglrdisaedtddeddddsglnplESTPGEISqnhfsPGDVFS 243
Cdd:COG5184     1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTD------------------------RSTPVRVP-----GLSNVV 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 244 QVAATDSASFALTTDGRVYGWGtfRGSDGVIGfNLQTRVQPTPVEIPGLKSITKLACGSNHVVALDMYGKVYTFGSGGQY 323
Cdd:COG5184    52 AVAAGGDHTCALKADGTVWCWG--NNSYGQLG-DGTTTDRTTPVKVPGLTGVVAVAAGYYHSCALKSDGTVWCWGDNSSG 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 324 QLGRKATTRHEG---TKAGLRPeccykfsskmhAVDISAGSYHSFFIDNHGEVWGWGLNNYSQTGhnDGTGQDDAMvlmP 400
Cdd:COG5184   129 QLGDGTTTNRLTpvqVDAGLSG-----------VVAIAAGGYHTCALKSDGTVWCWGANSYGQLG--DGTTTDRPT---P 192

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 401 RPIDSLSGrkISQIVGGEHHTVACTEDGELLTWGRIDGHQVGqrvdeyneDNTVFDENkrprilvAPTPIPGVH-ATSVA 479
Cdd:COG5184   193 VQVGGLSG--VVAVAAGGDHSCALKSDGTVWCWGSNSSGQLG--------DGTTTDRA-------TPVQVAGLTgVVAIA 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 480 AGTDTSFAIDEAGKVYSWGFSANYQTGQGTGDDIEVPTLIDNTAvrdrKIVWAGAGGQYSILAAESGKA---GQN--GQV 554
Cdd:COG5184   256 AGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLS----GVVAVAAGSSHTCALLTDGTVwcwGDNayGQL 331


                  ....*.
gi 1570010338 555 nghGNG 560
Cdd:COG5184   332 ---GDG 334
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
120-176 1.85e-05

Regulator of chromosome condensation (RCC1) repeat;


:

Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 42.12  E-value: 1.85e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1570010338 120 DIFVFGEGSSGELGLGSKKyDGKKPIDVKRPRINHnldsdkvgVVQVACGGMHVGAL 176
Cdd:pfam00415   3 RVYTWGRNDYGQLGLGTTE-NVLVPQKVEGLSGNK--------VVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 164-560 1.95e-54

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 187.49  E-value: 1.95e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 164 VQVACGGMHVGALTKDNKIYTWGVNDDRALGRDTTWDgglrdisaedtddeddddsglnplESTPGEISqnhfsPGDVFS 243
Cdd:COG5184     1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTD------------------------RSTPVRVP-----GLSNVV 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 244 QVAATDSASFALTTDGRVYGWGtfRGSDGVIGfNLQTRVQPTPVEIPGLKSITKLACGSNHVVALDMYGKVYTFGSGGQY 323
Cdd:COG5184    52 AVAAGGDHTCALKADGTVWCWG--NNSYGQLG-DGTTTDRTTPVKVPGLTGVVAVAAGYYHSCALKSDGTVWCWGDNSSG 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 324 QLGRKATTRHEG---TKAGLRPeccykfsskmhAVDISAGSYHSFFIDNHGEVWGWGLNNYSQTGhnDGTGQDDAMvlmP 400
Cdd:COG5184   129 QLGDGTTTNRLTpvqVDAGLSG-----------VVAIAAGGYHTCALKSDGTVWCWGANSYGQLG--DGTTTDRPT---P 192

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 401 RPIDSLSGrkISQIVGGEHHTVACTEDGELLTWGRIDGHQVGqrvdeyneDNTVFDENkrprilvAPTPIPGVH-ATSVA 479
Cdd:COG5184   193 VQVGGLSG--VVAVAAGGDHSCALKSDGTVWCWGSNSSGQLG--------DGTTTDRA-------TPVQVAGLTgVVAIA 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 480 AGTDTSFAIDEAGKVYSWGFSANYQTGQGTGDDIEVPTLIDNTAvrdrKIVWAGAGGQYSILAAESGKA---GQN--GQV 554
Cdd:COG5184   256 AGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLS----GVVAVAAGSSHTCALLTDGTVwcwGDNayGQL 331


                  ....*.
gi 1570010338 555 nghGNG 560
Cdd:COG5184   332 ---GDG 334
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
371-423 3.60e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 49.82  E-value: 3.60e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1570010338 371 GEVWGWGLNNYSQTGHndGTGQDdamVLMPRPIDSLSGRKISQIVGGEHHTVA 423
Cdd:pfam00415   2 GRVYTWGRNDYGQLGL--GTTEN---VLVPQKVEGLSGNKVVQVACGGDHTVA 49
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
120-176 1.85e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 42.12  E-value: 1.85e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1570010338 120 DIFVFGEGSSGELGLGSKKyDGKKPIDVKRPRINHnldsdkvgVVQVACGGMHVGAL 176
Cdd:pfam00415   3 RVYTWGRNDYGQLGLGTTE-NVLVPQKVEGLSGNK--------VVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 164-560 1.95e-54

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 187.49  E-value: 1.95e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 164 VQVACGGMHVGALTKDNKIYTWGVNDDRALGRDTTWDgglrdisaedtddeddddsglnplESTPGEISqnhfsPGDVFS 243
Cdd:COG5184     1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTD------------------------RSTPVRVP-----GLSNVV 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 244 QVAATDSASFALTTDGRVYGWGtfRGSDGVIGfNLQTRVQPTPVEIPGLKSITKLACGSNHVVALDMYGKVYTFGSGGQY 323
Cdd:COG5184    52 AVAAGGDHTCALKADGTVWCWG--NNSYGQLG-DGTTTDRTTPVKVPGLTGVVAVAAGYYHSCALKSDGTVWCWGDNSSG 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 324 QLGRKATTRHEG---TKAGLRPeccykfsskmhAVDISAGSYHSFFIDNHGEVWGWGLNNYSQTGhnDGTGQDDAMvlmP 400
Cdd:COG5184   129 QLGDGTTTNRLTpvqVDAGLSG-----------VVAIAAGGYHTCALKSDGTVWCWGANSYGQLG--DGTTTDRPT---P 192

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 401 RPIDSLSGrkISQIVGGEHHTVACTEDGELLTWGRIDGHQVGqrvdeyneDNTVFDENkrprilvAPTPIPGVH-ATSVA 479
Cdd:COG5184   193 VQVGGLSG--VVAVAAGGDHSCALKSDGTVWCWGSNSSGQLG--------DGTTTDRA-------TPVQVAGLTgVVAIA 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 480 AGTDTSFAIDEAGKVYSWGFSANYQTGQGTGDDIEVPTLIDNTAvrdrKIVWAGAGGQYSILAAESGKA---GQN--GQV 554
Cdd:COG5184   256 AGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLS----GVVAVAAGSSHTCALLTDGTVwcwGDNayGQL 331


                  ....*.
gi 1570010338 555 nghGNG 560
Cdd:COG5184   332 ---GDG 334
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 125-517 8.98e-54

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 185.95  E-value: 8.98e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 125 GEGSSGELGLGSKkYDGKKPIDVkrprinhnldSDKVGVVQVACGGMHVGALTKDNKIYTWGVNDDRALGRDTTWDgglr 204
Cdd:COG5184    23 GDNSYGQLGDGTT-TDRSTPVRV----------PGLSNVVAVAAGGDHTCALKADGTVWCWGNNSYGQLGDGTTTD---- 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 205 disaedtddeddddsglnplESTPGEISqnhfsPGDVFSQVAATDSASFALTTDGRVYGWGtfRGSDGVIGfNLQTRVQP 284
Cdd:COG5184    88 --------------------RTTPVKVP-----GLTGVVAVAAGYYHSCALKSDGTVWCWG--DNSSGQLG-DGTTTNRL 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 285 TPVEI-PGLKSITKLACGSNHVVALDMYGKVYTFGSGGQYQLGRKATTRHegtkagLRPEccyKFSSKMHAVDISAGSYH 363
Cdd:COG5184   140 TPVQVdAGLSGVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDR------PTPV---QVGGLSGVVAVAAGGDH 210

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 364 SFFIDNHGEVWGWGLNNYSQTGhnDGTGQDDAMvlmPRPIDSLSGrkISQIVGGEHHTVACTEDGELLTWGRIDGHQVGq 443
Cdd:COG5184   211 SCALKSDGTVWCWGSNSSGQLG--DGTTTDRAT---PVQVAGLTG--VVAIAAGGSHTCALKSDGTVWCWGDNSYGQLG- 282

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1570010338 444 rvdeyneDNTVFDENkrprilvAPTPIPGV-HATSVAAGTDTSFAIDEAGKVYSWGFSANYQTGQGTGDDIEVPT 517
Cdd:COG5184   283 -------DGTTTDRS-------TPVKVPGLsGVVAVAAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTTDRSTPV 343
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 296-561 4.94e-30

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 120.85  E-value: 4.94e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 296 TKLACGSNHVVALDMYGKVYTFGSGGQYQLGRKATTRHegtkagLRPEccyKFSSKMHAVDISAGSYHSFFIDNHGEVWG 375
Cdd:COG5184     1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDR------STPV---RVPGLSNVVAVAAGGDHTCALKADGTVWC 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 376 WGLNNYSQTGhnDGTGQDdamVLMPRPIDSLSGrkISQIVGGEHHTVACTEDGELLTWGRIDGHQVGqrvdeyneDNTVF 455
Cdd:COG5184    72 WGNNSYGQLG--DGTTTD---RTTPVKVPGLTG--VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLG--------DGTTT 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1570010338 456 DENkrprilvAPTPIP--GVHATSVAAGTDTSFAIDEAGKVYSWGFSANYQTGQGTGDDIEVPTLIDN-TAVRDrkivwA 532
Cdd:COG5184   137 NRL-------TPVQVDagLSGVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGlSGVVA-----V 204

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1570010338 533 GAGGQYSILAAESGK-----AGQNGQVnghGNGG 561
Cdd:COG5184   205 AAGGDHSCALKSDGTvwcwgSNSSGQL---GDGT 235
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
371-423 3.60e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 49.82  E-value: 3.60e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1570010338 371 GEVWGWGLNNYSQTGHndGTGQDdamVLMPRPIDSLSGRKISQIVGGEHHTVA 423
Cdd:pfam00415   2 GRVYTWGRNDYGQLGL--GTTEN---VLVPQKVEGLSGNKVVQVACGGDHTVA 49
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
258-308 8.37e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 48.67  E-value: 8.37e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1570010338 258 DGRVYGWGtfRGSDGVIGF-NLQTRVQPTPVEIPGLKSITKLACGSNHVVAL 308
Cdd:pfam00415   1 DGRVYTWG--RNDYGQLGLgTTENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
355-383 1.19e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 47.80  E-value: 1.19e-07
                          10        20
                  ....*....|....*....|....*....
gi 1570010338 355 VDISAGSYHSFFIDNHGEVWGWGLNNYSQ 383
Cdd:pfam13540   2 VSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
492-541 1.29e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 45.20  E-value: 1.29e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1570010338 492 GKVYSWGFSANYQTGQGTGDDIEVPTLIdnTAVRDRKIVWAGAGGQYSIL 541
Cdd:pfam00415   2 GRVYTWGRNDYGQLGLGTTENVLVPQKV--EGLSGNKVVQVACGGDHTVA 49
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
120-176 1.85e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 42.12  E-value: 1.85e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1570010338 120 DIFVFGEGSSGELGLGSKKyDGKKPIDVKRPRINHnldsdkvgVVQVACGGMHVGAL 176
Cdd:pfam00415   3 RVYTWGRNDYGQLGLGTTE-NVLVPQKVEGLSGNK--------VVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
312-367 2.93e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 41.35  E-value: 2.93e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1570010338 312 GKVYTFGSGGQYQLGRKATTRHegtkagLRPeCCYKFSSKMHAVDISAGSYHSFFI 367
Cdd:pfam00415   2 GRVYTWGRNDYGQLGLGTTENV------LVP-QKVEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
163-190 1.86e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 35.86  E-value: 1.86e-03
                          10        20
                  ....*....|....*....|....*...
gi 1570010338 163 VVQVACGGMHVGALTKDNKIYTWGVNDD 190
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSY 28
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
411-435 2.01e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 35.86  E-value: 2.01e-03
                          10        20
                  ....*....|....*....|....*
gi 1570010338 411 ISQIVGGEHHTVACTEDGELLTWGR 435
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGD 25
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
242-265 2.07e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 35.86  E-value: 2.07e-03
                          10        20
                  ....*....|....*....|....
gi 1570010338 242 FSQVAATDSASFALTTDGRVYGWG 265
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWG 24
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
295-324 8.12e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 33.94  E-value: 8.12e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1570010338 295 ITKLACGSNHVVALDMYGKVYTFGSGGQYQ 324
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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