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Conserved domains on  [gi|1017443439|emb|SAC36490|]
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GrpE [Enterobacter asburiae]

Protein Classification

nucleotide exchange factor GrpE( domain architecture ID 10793376)

nucleotide exchange factor GrpE functions as a nucleotide exchange factor for DnaK and participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may also function as a thermosensor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10325 PRK10325
heat shock protein GrpE; Provisional
 1-197 2.88e-126

heat shock protein GrpE; Provisional


:

Pssm-ID: 182379 [Multi-domain]  Cd Length: 197  Bit Score: 353.98  E-value: 2.88e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   1 MSSKEQKTPEGQAPEEIITEQHDEVEAVEPDASAEQVDPRDEKIANLEAQLVEAQNRERDGVLRIKAEMENLRRRTEQDV 80
Cdd:PRK10325    1 MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMV 160
Cdd:PRK10325   81 EKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV 160

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1017443439 161 ESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAKAKA 197
Cdd:PRK10325  161 ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA 197
 
Name Accession Description Interval E-value
PRK10325 PRK10325
heat shock protein GrpE; Provisional
 1-197 2.88e-126

heat shock protein GrpE; Provisional


Pssm-ID: 182379 [Multi-domain]  Cd Length: 197  Bit Score: 353.98  E-value: 2.88e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   1 MSSKEQKTPEGQAPEEIITEQHDEVEAVEPDASAEQVDPRDEKIANLEAQLVEAQNRERDGVLRIKAEMENLRRRTEQDV 80
Cdd:PRK10325    1 MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMV 160
Cdd:PRK10325   81 EKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV 160

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1017443439 161 ESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAKAKA 197
Cdd:PRK10325  161 ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA 197
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 45-195 4.42e-58

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 179.19  E-value: 4.42e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  45 ANLEAQLVEAQNRerdgVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPDNAAMIEGIE 124
Cdd:COG0576     2 EELEAELAELKDR----LLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAAEE-DEDVKSLLEGVE 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1017443439 125 LTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAKA 195
Cdd:COG0576    77 MTLKQLLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVLRPAMVVVAKG 147
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 59-192 6.94e-56

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 173.08  E-value: 6.94e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  59 RDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPDNAAMIEGIELTLKSMLDVVRKFG 138
Cdd:cd00446     4 KDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPK-EEELKNLLEGVEMTLKQLLKVLEKHG 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1017443439 139 VEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTV 192
Cdd:cd00446    83 VEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVLRPAMVVV 136
GrpE pfam01025
GrpE;
34-194 1.24e-48

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 155.84  E-value: 1.24e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  34 AEQVDPRDEKIANLEAQLVEAQNRerdgVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRALEVAdKAN 113
Cdd:pfam01025  10 TDEIESLEEEIEELEKKIEELKEK----LLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNSA-PEN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439 114 PDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVA 193
Cdd:pfam01025  85 EDVKSLLEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVLRPAMVVVS 164


                  .
gi 1017443439 194 K 194
Cdd:pfam01025 165 K 165
 
Name Accession Description Interval E-value
PRK10325 PRK10325
heat shock protein GrpE; Provisional
 1-197 2.88e-126

heat shock protein GrpE; Provisional


Pssm-ID: 182379 [Multi-domain]  Cd Length: 197  Bit Score: 353.98  E-value: 2.88e-126
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   1 MSSKEQKTPEGQAPEEIITEQHDEVEAVEPDASAEQVDPRDEKIANLEAQLVEAQNRERDGVLRIKAEMENLRRRTEQDV 80
Cdd:PRK10325    1 MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMV 160
Cdd:PRK10325   81 EKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV 160

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1017443439 161 ESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAKAKA 197
Cdd:PRK10325  161 ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA 197
PRK14150 PRK14150
heat shock protein GrpE; Provisional
 1-194 1.82e-92

heat shock protein GrpE; Provisional


Pssm-ID: 184539 [Multi-domain]  Cd Length: 193  Bit Score: 267.94  E-value: 1.82e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   1 MSSKEQKTPEGQAPEEIITEQHDEVEAVEPDAsAEQVDPRDEKIANLEAQLVEAQNRERDGVLRIKAEMENLRRRTEQDV 80
Cdd:PRK14150    1 MSNEEQKTPQEQVSEEIEAEVEQQEEADEAEL-EDELDEADARIAELEAQLAEAQAEERDSVLRARAEVENIRRRAEQDV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMV 160
Cdd:PRK14150   80 EKAHKFALEKFANELLPVIDNLERALQAADKENEALKALIEGVELTLKSLLDTVAKFGVEVVGPVGEPFNPEVHQAISMQ 159

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1017443439 161 ESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14150  160 ESEDHEPNTVMMVMQKGYTLNGRLLRPAMVMVSK 193
GrpE COG0576
Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein ...
 45-195 4.42e-58

Molecular chaperone GrpE (heat shock protein HSP-70) [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440341 [Multi-domain]  Cd Length: 147  Bit Score: 179.19  E-value: 4.42e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  45 ANLEAQLVEAQNRerdgVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPDNAAMIEGIE 124
Cdd:COG0576     2 EELEAELAELKDR----LLRLQAEFENYRKRTEREREEARKYALEKLAEDLLPVLDNLERALAAAEE-DEDVKSLLEGVE 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1017443439 125 LTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAKA 195
Cdd:COG0576    77 MTLKQLLDVLEKHGVEEIEPVGEPFDPNLHEAVSQVPSPDVEPGTVVEVLQKGYRLGDRVLRPAMVVVAKG 147
GrpE cd00446
nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70) ...
 59-192 6.94e-56

nucleotide exchange factor GrpE; GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. In bacteria, the DnaK-DnaJ-GrpE (KJE) chaperone system functions at the fulcrum of protein homeostasis. GrpE participates actively in response to heat shock by preventing aggregation of stress-denatured proteins; unfolded proteins initially bind to DnaJ, the J-domain ATPase-activating protein (Hsp40 family), whereupon DnaK hydrolyzes its bound ATP, resulting in a stable complex. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as Huntington's disease and ataxias.


Pssm-ID: 271355 [Multi-domain]  Cd Length: 136  Bit Score: 173.08  E-value: 6.94e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  59 RDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPDNAAMIEGIELTLKSMLDVVRKFG 138
Cdd:cd00446     4 KDKLLRAQAEFENYRKRTEKEKEEAKKYAIEKFAKDLLPVLDNLERALEAAPK-EEELKNLLEGVEMTLKQLLKVLEKHG 82

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1017443439 139 VEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTV 192
Cdd:cd00446    83 VEEIEPEGEKFDPNLHEAVMQVESPDKEPGTVVEVLQKGYKLHDRVLRPAMVVV 136
PRK14151 PRK14151
heat shock protein GrpE; Provisional
 23-195 5.32e-55

heat shock protein GrpE; Provisional


Pssm-ID: 172640 [Multi-domain]  Cd Length: 176  Bit Score: 172.65  E-value: 5.32e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  23 DEVEAVEPDASAEQVDPRDE---KIANLEAQLVEAQnrerDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVI 99
Cdd:PRK14151    5 QTLDLQAPEAAQAEAAAGDDltaRVQELEEQLAAAK----DQSLRAAADLQNVRRRAEQDVEKAHKFALEKFAGDLLPVV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439 100 DSLDRALEVADKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYT 179
Cdd:PRK14151   81 DSLERGLELSSADDEAIKPMREGVELTLKMFQDTLKRYQLEAVDPHGEPFNPEHHQAMAMQESADVEPNSVLKVFQKGYL 160

                         170
                  ....*....|....*.
gi 1017443439 180 LNGRTIRAAMVTVAKA 195
Cdd:PRK14151  161 LNGRLLRPAMVVVSKA 176
GrpE pfam01025
GrpE;
34-194 1.24e-48

GrpE;


Pssm-ID: 425996 [Multi-domain]  Cd Length: 165  Bit Score: 155.84  E-value: 1.24e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  34 AEQVDPRDEKIANLEAQLVEAQNRerdgVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRALEVAdKAN 113
Cdd:pfam01025  10 TDEIESLEEEIEELEKKIEELKEK----LLRALAEFENLRKRTEKEKEEAKKFAIEKFAKDLLPVIDNLERALNSA-PEN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439 114 PDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVA 193
Cdd:pfam01025  85 EDVKSLLEGVEMTLKQLLKILEKHGVEKIEPEGEPFDPNLHEAVSQVPSPEKPEGTVVEVLQKGYKLHDRVLRPAMVVVS 164


                  .
gi 1017443439 194 K 194
Cdd:pfam01025 165 K 165
PRK14139 PRK14139
heat shock protein GrpE; Provisional
 5-196 2.97e-47

heat shock protein GrpE; Provisional


Pssm-ID: 237621 [Multi-domain]  Cd Length: 185  Bit Score: 153.21  E-value: 2.97e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   5 EQKTPEGQAPEeiiTEQHDEVEAVEPDASAEQVDPrdekIANLEAQLVEAQNRER---DGVLRIKAEMENLRRRTEQDVE 81
Cdd:PRK14139    2 ENTQQNPSEQE---AEEAGAAAQAAAAAAAAAEDA----APALEAELAEAEAKAAelqDSFLRAKAETENVRRRAQEDVA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  82 KAHKFALEKFVNELLPVIDSLDRALevADKaNPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVE 161
Cdd:PRK14139   75 KAHKFAIESFAESLLPVKDSLEAAL--ADE-SGDLEKLREGVELTLKQLTSAFEKGRVVEINPVGEKFDPHQHQAISMVP 151

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1017443439 162 SEEvEAGKVLGVMQKGYTLNGRTIRAAMVTVAKAK 196
Cdd:PRK14139  152 AEQ-EPNTVVAVLQKGYTIADRVLRPALVTVAAPK 185
PRK14140 PRK14140
heat shock protein GrpE; Provisional
 1-194 7.81e-42

heat shock protein GrpE; Provisional


Pssm-ID: 237622 [Multi-domain]  Cd Length: 191  Bit Score: 139.36  E-value: 7.81e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   1 MSSKEQKT--PEGQAPEEIITEQHDEVEAVEPDASAEQVDPRDEKIANLEAQLVEAQNRErdgvLRIKAEMENLRRRTEQ 78
Cdd:PRK14140    1 MEEKNEQVeeEVEETEVEEAVEDEVEEETVEEESEAELLDEEQAKIAELEAKLDELEERY----LRLQADFENYKRRIQK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  79 DVEKAHKFALEKFVNELLPVIDSLDRALEVADKaNPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIA 158
Cdd:PRK14140   77 ENEAAEKYRAQSLASDLLPALDNFERALQIEAD-DEQTKSLLKGVEMVHRQLLEALKKEGVEVIEAVGEQFDPNLHQAVM 155

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1017443439 159 MVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14140  156 QDEDEDFESNEVVEELQKGYKLKDRVIRPSMVKVNQ 191
PRK14144 PRK14144
heat shock protein GrpE; Provisional
 20-194 6.16e-38

heat shock protein GrpE; Provisional


Pssm-ID: 184535 [Multi-domain]  Cd Length: 199  Bit Score: 129.84  E-value: 6.16e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  20 EQHDEVEAVEPDASAEQVDPRDE---------KIANLEAQLVEAQNRERDG---VLRIKAEMENLRRRTEQDVEKAHKFA 87
Cdd:PRK14144   14 DEHKEEHKVENEILEEETDEESQhqepalghpSYTALEEQLTLAEQKAHENwekSVRALAELENVRRRMEREVANAHKYG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  88 LEKFVNELLPVIDSLDRALEVADKAnpDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEA 167
Cdd:PRK14144   94 VEKLISALLPVVDSLEQALQLADKN--SDPSMHEGLELTMKLFLDALQKFDVEQIDPLGQTFDPQQHEAMSMQPAPGAPP 171

                         170       180
                  ....*....|....*....|....*..
gi 1017443439 168 GKVLGVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14144  172 NSVITVFQKGYKLSDRVIRPARVIVST 198
PRK14148 PRK14148
heat shock protein GrpE; Provisional
 2-194 1.38e-34

heat shock protein GrpE; Provisional


Pssm-ID: 172637 [Multi-domain]  Cd Length: 195  Bit Score: 121.01  E-value: 1.38e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   2 SSKEQKTPEGQAPEEIITEQHDEVEAVEPDASAEQVDPRDEKIANLEaqlvEAQNRERDGVLRIKAEMENLRRRTEQDVE 81
Cdd:PRK14148    7 SNVEDKSLDIETAAQVETAQESASGALEELSVEEQLERAKDTIKELE----DSCDQFKDEALRAKAEMENIRKRAERDVS 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  82 KAHKFALEKFVNELLPVIDSLDRALEVADKANpDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVE 161
Cdd:PRK14148   83 NARKFGIEKFAKELLPVIDSIEQALKHEVKLE-EAIAMKEGIELTAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIP 161

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1017443439 162 SEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14148  162 NPEFEDNTIFDVFQKGYMLNGRIVRAAKVVIVK 194
PRK14158 PRK14158
heat shock protein GrpE; Provisional
 12-194 3.77e-34

heat shock protein GrpE; Provisional


Pssm-ID: 172646 [Multi-domain]  Cd Length: 194  Bit Score: 120.04  E-value: 3.77e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  12 QAPEEIITEQHDEVEAVEPDASAEQVDPRDEKIANLEAQLV--EAQNRER-DGVLRIKAEMENLRRRTEQDVEKAHKFAL 88
Cdd:PRK14158   10 QIAEALKAKAAKEAEAAQGKPEAAQPVAAADRIKELEEALAakEAEAAANwDKYLRERADLENYRKRVQKEKEELLKYGN 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  89 EKFVNELLPVIDSLDRALEVADKANPdnAAMIEGIELTLKSMLDVVRKFGVEVI-ADTDVPLDPNVHQAIAMVESEEVEA 167
Cdd:PRK14158   90 ESLILEILPAVDNMERALDHADEESM--SAIIEGIRMTLSMLLSTLKKFGVTPVeAEKGTPFDPAYHQAMCQVESAEQEP 167

                         170       180
                  ....*....|....*....|....*..
gi 1017443439 168 GKVLGVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14158  168 NTVVAVFQKGYLLNERLLRPAMVSVAT 194
PRK14147 PRK14147
heat shock protein GrpE; Provisional
 18-194 4.82e-34

heat shock protein GrpE; Provisional


Pssm-ID: 237625 [Multi-domain]  Cd Length: 172  Bit Score: 118.90  E-value: 4.82e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  18 ITEQHDEVEAVEPDASAEQVDPRDEKIANLEAQLVEAqnreRDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLP 97
Cdd:PRK14147    1 MNQDHPEFDSEDLAQNPPETDPLKAEVESLRSEIALV----KADALRERADLENQRKRIARDVEQARKFANEKLLGELLP 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  98 VIDSLDRALEVAdkaNPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKG 177
Cdd:PRK14147   77 VFDSLDAGLTAA---GTEPSPLRDGLELTYKQLLKVAADNGLTLLDPVGQPFNPEHHQAISQGEAEGVAPGHVVQVFQKG 153

                         170
                  ....*....|....*..
gi 1017443439 178 YTLNGRTIRAAMVTVAK 194
Cdd:PRK14147  154 YLLNERLLRPALVVVAK 170
PRK14141 PRK14141
heat shock protein GrpE; Provisional
 3-197 1.68e-33

heat shock protein GrpE; Provisional


Pssm-ID: 172630  Cd Length: 209  Bit Score: 118.62  E-value: 1.68e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   3 SKEQKTPEGQAPEEIiteqhDEVEAVEPDASAEQVDPRDEKIANLEAQLVEAqnreRDGVLRIKAEMENLRRRTEQDVEK 82
Cdd:PRK14141    4 EKNKNGNPADAARDA-----NNPVDREAKPYEMEDDPEPDPLEALKAENAEL----KDRMLRLAAEMENLRKRTQRDVAD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  83 AHKFALEKFVNELLPVIDSLDRAL-----EVADKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAI 157
Cdd:PRK14141   75 ARAYGIAGFARDMLSVSDNLRRALdaipaEARAAADAGLKALIEGVEMTERAMLNALERHGVKKLDPEGQKFDPNFHQAM 154

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1017443439 158 AMVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAKAKA 197
Cdd:PRK14141  155 FEVPNPDVPNNTVVQVVQAGYTIGERVLRPAMVGVAKGGP 194
PRK14149 PRK14149
heat shock protein GrpE; Provisional
 1-194 2.69e-32

heat shock protein GrpE; Provisional


Pssm-ID: 184538 [Multi-domain]  Cd Length: 191  Bit Score: 114.97  E-value: 2.69e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   1 MSSKEQKTPEGQAPEEIitEQHDEVEAVEPDASAEQVDPRDEKIANLEAQLVEAqnreRDGVLRIKAEMENLRRRTEQDV 80
Cdd:PRK14149    4 EHNQEHDHLSQKEPESE--EKACACKEQQGEEKQEASEKEGEIKEDFELKYKEM----HEKYLRVHADFENVKKRLERDK 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  81 EKAHKFALEKFVNELLPVIDSLDRALEVAdKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIAdTDVPLDPNVHQAIAMV 160
Cdd:PRK14149   78 SMALEYAYEKIALDLLPVIDALLGALKSA-AEVDKESALTKGLELTMEKLHEVLARHGIEGIE-CLEEFDPNFHNAIMQV 155

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1017443439 161 ESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14149  156 KSEEKENGKIVQVLQQGYKYKGRVLRPAMVSIAK 189
PRK14155 PRK14155
heat shock protein GrpE; Provisional
 26-193 2.02e-27

heat shock protein GrpE; Provisional


Pssm-ID: 237627 [Multi-domain]  Cd Length: 208  Bit Score: 102.74  E-value: 2.02e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  26 EAVEPDASAEQVDPRDEKIANLEAQLVEAqnreRDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRA 105
Cdd:PRK14155    4 EQTPAEDGPFEADDAAQEIEALKAEVAAL----KDQALRYAAEAENTKRRAEREMNDARAYAIQKFARDLLGAADNLGRA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439 106 LEVA--DKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTD-VPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNG 182
Cdd:PRK14155   80 TAASpkDSADPAVKNFIIGVEMTEKELLGAFERNGLKKIDPAKgDKFDPHLHQAMMEQPSTEVAAGGVLQVMQAGYELMG 159

                         170
                  ....*....|.
gi 1017443439 183 RTIRAAMVTVA 193
Cdd:PRK14155  160 RLVRPAMVAVA 170
PRK14154 PRK14154
heat shock protein GrpE; Provisional
 1-193 3.57e-25

heat shock protein GrpE; Provisional


Pssm-ID: 237626 [Multi-domain]  Cd Length: 208  Bit Score: 97.19  E-value: 3.57e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   1 MSSKEQKTPEGQAPE--EIITEQHDEVEAVEPDASAEQVDPRD----EKIANLEAQLVEAQNR---ERDGVLRIKAEMEN 71
Cdd:PRK14154    5 MSSKNNPESETKAKNkwEKVMEAEEEQEEGGGDGSQEMEPHREglefPSREKLEGQLTRMERKvdeYKTQYLRAQAEMDN 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  72 LRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRALEVADKANPDNAAMIEGIELTLKSMLDVVRKFGVEVI-ADTDVPLD 150
Cdd:PRK14154   85 LRKRIEREKADIIKFGSKQLITDLLPVADSLIHGLESPASEDPQVKSMRDGMSLTLDLLHNTLAKHGVQVInPNPGDPFD 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1017443439 151 PNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVA 193
Cdd:PRK14154  165 PALHEAMSVQAVPDAKPDTIIQVLQKGYQLNGRVLRAARVIVA 207
PRK14153 PRK14153
heat shock protein GrpE; Provisional
 29-194 6.73e-25

heat shock protein GrpE; Provisional


Pssm-ID: 184540 [Multi-domain]  Cd Length: 194  Bit Score: 96.06  E-value: 6.73e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  29 EPDASAEQVDPRDEKIANLEAQLVEAQNRE-RDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRALE 107
Cdd:PRK14153   22 SAEEAEELKEEPEDSTADSETEKCREEIESlKEQLFRLAAEFDNFRKRTAREMEENRKFVLEQVLLDLLEVTDNFERALE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439 108 VADKANpDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGRTIRA 187
Cdd:PRK14153  102 SARTAE-DMNSIVEGIEMVSKQFFSILEKYGLERIECEGEEFDPHRHEAMMHVETSEVPDNTIVDVCKPGYALNSKVIRP 180


                  ....*..
gi 1017443439 188 AMVTVAK 194
Cdd:PRK14153  181 AMVSVAR 187
PRK14159 PRK14159
heat shock protein GrpE; Provisional
 18-194 1.86e-23

heat shock protein GrpE; Provisional


Pssm-ID: 172647 [Multi-domain]  Cd Length: 176  Bit Score: 91.67  E-value: 1.86e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  18 ITEQHDEVEAVEPDASAEQVDPRDEKIANLEAQLVEAQNRE-RDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELL 96
Cdd:PRK14159    1 MSEQKQEFENENAENSEHLQDENLQNIEDVEQNKLQKDYDElKDKYMRANAEFENIKKRMEKEKLSAMAYANESFAKDLL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  97 PVIDSLDRALEVadKANPDNAAMI-EGIELTLKSMLDVVRKFGVEVIaDTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQ 175
Cdd:PRK14159   81 DVLDALEAAVNV--ECHDEISLKIkEGVQNTLDLFLKKLEKHGVALI-KEEKEFDPNLHEAMFHVDSENHQSGEVVQVLQ 157

                         170
                  ....*....|....*....
gi 1017443439 176 KGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14159  158 KGYKIADRVIRPTKVSVAK 176
PRK14162 PRK14162
heat shock protein GrpE; Provisional
 3-194 1.27e-21

heat shock protein GrpE; Provisional


Pssm-ID: 237631 [Multi-domain]  Cd Length: 194  Bit Score: 87.20  E-value: 1.27e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   3 SKEQKTPEGQAPEEIITEQHDEveAVEPDASAEQVDPRDEKIANLEAQLVEAQNRER---DGVLRIKAEMENLRRRTEQD 79
Cdd:PRK14162    2 SKEEFPSEKDLPQEETTDEAPK--KEAKEAPKEEDQEKQNPVEDLEKEIADLKAKNKdleDKYLRSQAEIQNMQNRYAKE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  80 VEKAHKFALEKFVNELLPVIDSLDRALEVadKANPDNAAMIE-GIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIA 158
Cdd:PRK14162   80 RAQLIKYESQSLAKDVLPAMDNLERALAV--KADDEAAKQLKkGVQMTLDHLVKALKDHGVTEIKADGEKFDPTLHQAVQ 157

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1017443439 159 MVESEEVE-AGKVLGVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14162  158 TVAAENDDqKDHVVQVLQKGYQYKDRTLRPAMVVVAQ 194
PRK14160 PRK14160
heat shock protein GrpE; Provisional
 1-194 2.11e-21

heat shock protein GrpE; Provisional


Pssm-ID: 237629 [Multi-domain]  Cd Length: 211  Bit Score: 87.12  E-value: 2.11e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   1 MSSKEQKTPEGQAPEEIITEQHDEVEAVEPDASAEQVDPRDEKiANLEAQLVEAQNRerdgVLRIKAEMENLRRRTEQDV 80
Cdd:PRK14160   28 KGKEEDLEFEEIEKEEIIEDSEESNEVKIEELKDENNKLKEEN-KKLENELEALKDR----LLRTVAEYDNYRKRTAKEK 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  81 EKAHKFALEKFVNELLPVIDSLDRALEVADKANPdnaaMIEGIELTLKSMLDVVRKFGVEVIaDTDVPLDPNVHQAIAMV 160
Cdd:PRK14160  103 EGIYSDACEDVLKELLPVLDNLERAAAVEGSVED----LKKGIEMTVKQFKTSLEKLGVEEI-STEGEFDPNLHNAVMHV 177

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1017443439 161 ESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14160  178 EDENYGENEIVEVFQKGYKRGDKVIRYSMVKVAN 211
PRK14145 PRK14145
heat shock protein GrpE; Provisional
 23-194 4.51e-21

heat shock protein GrpE; Provisional


Pssm-ID: 184536 [Multi-domain]  Cd Length: 196  Bit Score: 86.13  E-value: 4.51e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  23 DEVEAVEPDASAEQVDPRDEKIANLEAQLVEAQNReRDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSL 102
Cdd:PRK14145   30 EDEQAQQNQPQQQTVDEIEELKQKLQQKEVEAQEY-LDIAQRLKAEFENYRKRTEKEKSEMVEYGKEQVILELLPVMDNF 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439 103 DRALEvadkANPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNG 182
Cdd:PRK14145  109 ERALA----SSGDYNSLKEGIELIYRQFKKILDKFGVKEIEAEGQIFDPYKHHAVMQEEVEGKQPNEIIEVFQKGYYLKD 184

                         170
                  ....*....|..
gi 1017443439 183 RTIRAAMVTVAK 194
Cdd:PRK14145  185 KVIRPSLVKVAK 196
PRK14143 PRK14143
heat shock protein GrpE; Provisional
 2-196 5.84e-21

heat shock protein GrpE; Provisional


Pssm-ID: 237624 [Multi-domain]  Cd Length: 238  Bit Score: 86.71  E-value: 5.84e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   2 SSKEQKTPEGQAPEEIITEQHDEVEAVEPDASAEQVDPRDEKIANLEAQL--VEAQNRERDG-VLRIKAEMENLRRRTEQ 78
Cdd:PRK14143   27 SSEEVTEQEAELTNPEGDAAEAESSPDSGSAASETAADNAARLAQLEQELesLKQELEELNSqYMRIAADFDNFRKRTSR 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  79 DVEKAHKFALEKFVNELLPVIDSLDRALEVADKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIA 158
Cdd:PRK14143  107 EQEDLRLQLKCNTLSEILPVVDNFERARQQLKPEGEEAQALHRSYQGLYKQLVDVLKRLGVSPMRVVGQEFDPNLHEAVL 186

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1017443439 159 MVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVAKAK 196
Cdd:PRK14143  187 REPSDEHPEDVVLEELQRGYHLGGRVLRHAMVKVSMGP 224
PRK14163 PRK14163
heat shock protein GrpE; Provisional
 9-196 2.45e-18

heat shock protein GrpE; Provisional


Pssm-ID: 184546 [Multi-domain]  Cd Length: 214  Bit Score: 79.40  E-value: 2.45e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   9 PEGQAPEEIITEQHDEveavEPDASAEQVDPRDEKIANLEaQLVEAQNRERDGVLRIKAEMENLRRRTEQDVEKAHKFAL 88
Cdd:PRK14163   15 PSGATPDDAEPKAASE----EGAAPAGDAAATAGLTAQLD-QVRTALGERTADLQRLQAEYQNYRRRVERDRVTVKEIAV 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  89 EKFVNELLPVIDSLDRALEvadkanpdNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAG 168
Cdd:PRK14163   90 ANLLSELLPVLDDVGRARE--------HGELVGGFKSVAESLETTVAKLGLQQFGKEGEPFDPTIHEALMHSYAPDVTET 161

                         170       180
                  ....*....|....*....|....*...
gi 1017443439 169 KVLGVMQKGYTLNGRTIRAAMVTVAKAK 196
Cdd:PRK14163  162 TCVAILQPGYRIGERTIRPARVAVAEPQ 189
PRK14161 PRK14161
heat shock protein GrpE; Provisional
 26-194 6.18e-17

heat shock protein GrpE; Provisional


Pssm-ID: 237630 [Multi-domain]  Cd Length: 178  Bit Score: 74.63  E-value: 6.18e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  26 EAVEPDASAEQVDPRDEKIANLEAQLVEAQnrerDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRA 105
Cdd:PRK14161   10 EQTINDIAEEIVETANPEITALKAEIEELK----DKLIRTTAEIDNTRKRLEKARDEAKDYAIATFAKELLNVSDNLSRA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439 106 LE-VADKANPDNAAMIEGIELTLKSMLDVVRKFGVEVIA-DTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGR 183
Cdd:PRK14161   86 LAhKPANSDVEVTNIIAGVQMTKDELDKVFHKHHIEEIKpEIGSMFDYNLHNAISQIEHPDHAPNSIITLMQSGYKIRDR 165

                         170
                  ....*....|.
gi 1017443439 184 TIRAAMVTVAK 194
Cdd:PRK14161  166 LLRPATVQVVK 176
PRK14164 PRK14164
heat shock protein GrpE; Provisional
 6-193 8.11e-17

heat shock protein GrpE; Provisional


Pssm-ID: 237632 [Multi-domain]  Cd Length: 218  Bit Score: 75.22  E-value: 8.11e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   6 QKTPEGQAPEEIITEQHDEVEAVEPDASAEQVDPRDEKIAnlEAQLVEAQNRERDGVL-RIKAEMENLRRRTEQDVEKAH 84
Cdd:PRK14164   38 QGVPEDDPFGDAVEGEIDPDLEADLEDLLDDVDPELADDG--EASTVEAQLAERTEDLqRVTAEYANYRRRTERERQAII 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  85 KFALEKFVNELLPVIDSLDRALEVADkanpdnaaMIEGielTLKSMLD----VVRKFGVEVIADTDVPLDPNVHQAIAMV 160
Cdd:PRK14164  116 ETAKAGVATDLLPILDDLDLAEQHGD--------LNEG---PLKAFSDkltnVLAGLKVEKFGEEGDAFDPEIHEAVQDL 184

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1017443439 161 ESEEVeagKVLG-VMQKGYTLNGRTIRAAMVTVA 193
Cdd:PRK14164  185 SSGDE---KVLGtVLRKGYRMGDRVLRTAMVIIA 215
PRK14146 PRK14146
heat shock protein GrpE; Provisional
 5-197 5.47e-15

heat shock protein GrpE; Provisional


Pssm-ID: 172635 [Multi-domain]  Cd Length: 215  Bit Score: 70.15  E-value: 5.47e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   5 EQKTPEGQAPEEIITEQHDEVEAVEPDASAEQVDPRDEKIANLEAQLVEAQNReRDGVLRIKAEMENLRRRTEQDVEKAH 84
Cdd:PRK14146   21 QSQTLEESKLENMNSEESQTITEETQEQAVEGAETETSLQKELDNAKKEIESL-KDSWARERAEFQNFKRRSAQEFVSIR 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  85 KFALEKFVNELLPVIDSLDRALEVADKAnPDNAAMIEGIELTLKSMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEE 164
Cdd:PRK14146  100 KEAVKSLVSGFLNPIDNLERVGATQNQS-EELKPFVEGVKMILKEFYSVLEKSNVIRFDPKGEPFDPMSMEALSSEEGDQ 178

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1017443439 165 VEAGKVLGVMQKGYTL----NGRTIRAAMVTVAKAKA 197
Cdd:PRK14146  179 YSEETVIDVYQAGYYYkeneDKFTLRPARVRIGKPKS 215
PRK14156 PRK14156
heat shock protein GrpE; Provisional
 15-194 7.20e-14

heat shock protein GrpE; Provisional


Pssm-ID: 237628 [Multi-domain]  Cd Length: 177  Bit Score: 66.39  E-value: 7.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  15 EEIITEQHDE-VEAVEPDASAEQVDPRDEKIANLEAQLVEAQNRErDGVLRIKAEMENLRRRTEQDVEKAHKFALEKFVN 93
Cdd:PRK14156    3 EEIKNEEVEEeVEATETEETVEEVVEETPEKSELELANERADEFE-NKYLRAHAEMQNIQRRANEERQQLQRYRSQDLAK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  94 ELLPVIDSLDRALEVADKANPdnaaMIEGIELTLKSMLDVVRKFGVEVIADTDvpLDPNVHQAIAMVES-EEVEAGKVLG 172
Cdd:PRK14156   82 AILPSLDNLERALAVEGLTDD----VKKGLEMVQESLIQALKEEGVEEVAVDS--FDHNLHMAVQTLPAdDEHPADSIAQ 155

                         170       180
                  ....*....|....*....|..
gi 1017443439 173 VMQKGYTLNGRTIRAAMVTVAK 194
Cdd:PRK14156  156 VFQKGYKLHERLLRPAMVVVYN 177
PRK14157 PRK14157
heat shock protein GrpE; Provisional
 49-193 1.90e-09

heat shock protein GrpE; Provisional


Pssm-ID: 184543 [Multi-domain]  Cd Length: 227  Bit Score: 55.35  E-value: 1.90e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  49 AQLVEAQNRERdgvlrikAEMENLRRRTEQDVEKAHKFALEKFVNELLPVIDSLDRALEvadkanpdNAAMIEGIELTLK 128
Cdd:PRK14157   94 AEYLEALQRER-------AEFINYRNRTQKEQDRFRQHGIIDVLTALLPALDDIDRIRE--------HSEMDDSFKAVAA 158

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1017443439 129 SMLDVVRKFGVEVIADTDVPLDPNVHQAIAMVESEEVEAGKVLGVMQKGYTLNGRTIRAAMVTVA 193
Cdd:PRK14157  159 KIDKAFEKFGVEKFGEKGEDFDPTKHDAILHKPDPDAEKETVDTVVEAGYRIGDRVIRAARVVVA 223
PRK14142 PRK14142
heat shock protein GrpE; Provisional
 9-192 5.82e-07

heat shock protein GrpE; Provisional


Pssm-ID: 237623  Cd Length: 223  Bit Score: 48.07  E-value: 5.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439   9 PEGQAPEEI-------ITEQHDEVEAVEPD-----ASAEQVDPRDEKIANLEAQLveaqnrerdgvLRIKAEMENLRRRT 76
Cdd:PRK14142    2 PDGNSGEQVtvtdkrrIDPETGEVRHVPPGdmpggTAAADAAHTEDKVAELTADL-----------QRVQADFANYRKRA 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1017443439  77 EQDVEKAHKFALEKFVNELLPVIDSLDRALEVADKANPDNAAMIEGIELTLKSMLDVVrkFGVEviadtDVPLDPNVHQA 156
Cdd:PRK14142   71 LRDQQAAADRAKASVVSQLLGVLDDLERARKHGDLESGPLKSVADKLDSALTGLGLVA--FGAE-----GEDFDPVLHEA 143

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1017443439 157 IAMvESEEVEAGK-VLG-VMQKGYTLNGRTIRAAMVTV 192
Cdd:PRK14142  144 VQH-EGDGGQGSKpVIGtVMRQGYQLGEQVLRHALVGV 180
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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