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Conserved domains on  [gi|1032797910|emb|SAL89101|]
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MHC class I antigen, partial [Homo sapiens]

Protein Classification

HLA class I histocompatibility antigen alpha chain family protein( domain architecture ID 10444360)

HLA class I histocompatibility antigen alpha chain family protein similar to Mus musculus H-2 class I histocompatibility antigen, Q9 alpha chain, which is involved in the presentation of foreign antigens to the immune system

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MHC_I pfam00129
Class I Histocompatibility antigen, domains alpha 1 and 2;
1-178 1.53e-120

Class I Histocompatibility antigen, domains alpha 1 and 2;


:

Pssm-ID: 395078  Cd Length: 179  Bit Score: 337.83  E-value: 1.53e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032797910   1 SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPAYWDRETQISKTNTQTYRESLRNL 80
Cdd:pfam00129   2 SHSLRYFYTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDAANPRMEPRAPWIEQEGPEYWERETQIAKGNEQIFRENLRTL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032797910  81 RGYYNQSEAGSHTLQRMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAREAEQWRAYLE 160
Cdd:pfam00129  82 LGYYNQSEGGSHTLQWMYGCDVGPDGRLLRGYEQFAYDGKDYIALNEDLRSWTAADPAAQITKRKWEAAGEAERQRAYLE 161

                         170
                  ....*....|....*...
gi 1032797910 161 GLCVEWLRRYLENGKETL 178
Cdd:pfam00129 162 GECVEWLRRYLENGKETL 179
 
Name Accession Description Interval E-value
MHC_I pfam00129
Class I Histocompatibility antigen, domains alpha 1 and 2;
1-178 1.53e-120

Class I Histocompatibility antigen, domains alpha 1 and 2;


Pssm-ID: 395078  Cd Length: 179  Bit Score: 337.83  E-value: 1.53e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032797910   1 SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPAYWDRETQISKTNTQTYRESLRNL 80
Cdd:pfam00129   2 SHSLRYFYTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDAANPRMEPRAPWIEQEGPEYWERETQIAKGNEQIFRENLRTL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032797910  81 RGYYNQSEAGSHTLQRMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAREAEQWRAYLE 160
Cdd:pfam00129  82 LGYYNQSEGGSHTLQWMYGCDVGPDGRLLRGYEQFAYDGKDYIALNEDLRSWTAADPAAQITKRKWEAAGEAERQRAYLE 161

                         170
                  ....*....|....*...
gi 1032797910 161 GLCVEWLRRYLENGKETL 178
Cdd:pfam00129 162 GECVEWLRRYLENGKETL 179
 
Name Accession Description Interval E-value
MHC_I pfam00129
Class I Histocompatibility antigen, domains alpha 1 and 2;
1-178 1.53e-120

Class I Histocompatibility antigen, domains alpha 1 and 2;


Pssm-ID: 395078  Cd Length: 179  Bit Score: 337.83  E-value: 1.53e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032797910   1 SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAPWIEQEGPAYWDRETQISKTNTQTYRESLRNL 80
Cdd:pfam00129   2 SHSLRYFYTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDAANPRMEPRAPWIEQEGPEYWERETQIAKGNEQIFRENLRTL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1032797910  81 RGYYNQSEAGSHTLQRMYGCDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAAREAEQWRAYLE 160
Cdd:pfam00129  82 LGYYNQSEGGSHTLQWMYGCDVGPDGRLLRGYEQFAYDGKDYIALNEDLRSWTAADPAAQITKRKWEAAGEAERQRAYLE 161

                         170
                  ....*....|....*...
gi 1032797910 161 GLCVEWLRRYLENGKETL 178
Cdd:pfam00129 162 GECVEWLRRYLENGKETL 179
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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